J. Leza

J. Leza, B. García-Bueno, J. Madrigal, 2017, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

Dysregulated peripheral endocannabinoid system signaling is associated with cognitive deficits in first-episode psychosis.

J. Leza, P. Sáiz, A. Lobo, 2016, Journal of psychiatric research.

Inflammatory activation and cholinergic anti-inflammatory system in eating disorders

J. Leza, M. Dı́az-Marsá, J. Carrasco, 2013, Brain, Behavior, and Immunity.

The effects of physical and psychological stress on the gastro-intestinal tract: lessons from animal models.

J. Leza, L. Menchen, J. Caso, 2008, Current molecular medicine.

Corticosterone basal levels and vulnerability to LPS-induced neuroinflammation in the rat brain

J. Leza, B. García-Bueno, J. L. Madrigal, 2010, Brain Research.

Regulatory role of the cannabinoid CB2 receptor in stress‐induced neuroinflammation in mice

J. Leza, J. Manzanares, B. García-Bueno, 2014, British journal of pharmacology.

Regulatory Role of Cannabinoid Receptor 1 in Stress-Induced Excitotoxicity and Neuroinflammation

J. Leza, J. Manzanares, B. García-Bueno, 2011, Neuropsychopharmacology.

Stress-induced increase in extracellular sucrose space in rats is mediated by nitric oxide

I. Lizasoain, J. Leza, P. Lorenzo, 2002, Brain Research.

In Vitro Ischemic Tolerance Involves Upregulation of Glutamate Transport Partly Mediated by the TACE/ADAM17-Tumor Necrosis Factor-α Pathway

O. Hurtado, I. Lizasoain, A. Cárdenas, 2004, The Journal of Neuroscience.

Risperidone administered during adolescence induced metabolic, anatomical and inflammatory/oxidative changes in adult brain: A PET and MRI study in the maternal immune stimulation animal model

J. Leza, M. Desco, D. García-García, 2019, European Neuropsychopharmacology.

CIBERSAM: Ten years of collaborative translational research in mental disorders

L. Fañanás, J. Ayuso-Mateos, J. Leza, 2019, Revista de Psiquiatría y Salud Mental (English Edition).

CIBERSAM: Ten years of collaborative translational research in mental disorders.

L. Fañanás, J. Ayuso-Mateos, J. Leza, 2019, Revista de psiquiatria y salud mental.

Inflammation in schizophrenia: A question of balance

Celso Arango, Miguel Bernardo, J. Leza, 2015, Neuroscience & Biobehavioral Reviews.

Cardiovascular Risk in Early Psychosis: Relationship with Inflammation and Clinical Features 6 Months after Diagnosis

J. Leza, J. Bobes, A. Lobo, 2017, The international journal of neuropsychopharmacology.

Paliperidone reverts Toll-like receptor 3 signaling pathway activation and cognitive deficits in a maternal immune activation mouse model of schizophrenia

J. Leza, B. García-Bueno, J. Madrigal, 2017, Neuropharmacology.

The Atypical Antipsychotic Paliperidone Regulates Endogenous Antioxidant/Anti-Inflammatory Pathways in Rat Models of Acute and Chronic Restraint Stress

J. Leza, B. García-Bueno, J. Madrigal, 2016, Neurotherapeutics.

Expression and Function of Tumour Necrosis Factor-α-Converting Enzyme in the Central Nervous System

O. Hurtado, I. Lizasoain, A. Cárdenas, 2003, Neurosignals.

Expression and function of tumour necrosis factor-alpha-converting enzyme in the central nervous system.

O. Hurtado, I. Lizasoain, A. Cárdenas, 2003, Neuro-Signals.

Toll-like 4 receptor inhibitor TAK-242 decreases neuroinflammation in rat brain frontal cortex after stress

J. Leza, B. García-Bueno, J. Madrigal, 2014, Journal of Neuroinflammation.

Alcohol binge disrupts the rat intestinal barrier: the partial protective role of oleoylethanolamide

J. Leza, B. García-Bueno, A. del Pozo, 2018, British journal of pharmacology.

Immune–Inflammatory Biomarkers Predict Cognition and Social Functioning in Patients With Type 2 Diabetes Mellitus, Major Depressive Disorder, Bipolar Disorder, and Schizophrenia: A 1-Year Follow-Up Study

J. Leza, R. Tabarés-Seisdedos, E. Vieta, 2022, Frontiers in Neurology.

Neuroplasticity and inflammatory alterations in the nucleus accumbens are corrected after risperidone treatment in a schizophrenia-related developmental model in rats

J. Leza, J. Madrigal, D. Martín-Hernández, 2021, Schizophrenia Research.

Dysfunction of Inflammatory Pathways and Their Relationship With Psychological Factors in Adult Female Patients With Eating Disorders

J. Leza, M. Dı́az-Marsá, J. Carrasco, 2022, Frontiers in Pharmacology.

Early responses to deep brain stimulation in depression are modulated by anti-inflammatory drugs

J. Leza, D. Puigdemont, V. Pérez, 2014, Molecular Psychiatry.

Discrimination between Alzheimer's Disease and Late Onset Bipolar Disorder Using Multivariate Analysis.

Manuel Graña, Darya Chyzhyk, Borja Ayerdi, 2015 .

Astrocyte-Derived MCP-1 Mediates Neuroprotective Effects of Noradrenaline

J. Leza, S. Kalinin, D. Feinstein, 2009, The Journal of Neuroscience.

Cerebrospinal fluid and plasma concentrations of nitric oxide metabolites are increased in dementia with Lewy bodies

I. Lizasoain, J. Leza, M. A. Moro, 2002, Neuroscience Letters.

Dual effects of noradrenaline on astroglial production of chemokines and pro-inflammatory mediators

J. Leza, Ara E. Hinojosa, B. García-Bueno, 2013, Journal of Neuroinflammation.

The relationship between prepulse inhibition and general psychopathology in patients with schizophrenia treated with long-acting risperidone

J. Leza, G. Rubio, J. Borrell, 2009, Schizophrenia Research.

CCL2 Inhibition of Pro-Resolving Mediators Potentiates Neuroinflammation in Astrocytes

J. Leza, B. García-Bueno, J. L. Madrigal, 2022, International journal of molecular sciences.

Sphk2 deletion is involved in structural abnormalities and Th17 response but does not aggravate colon inflammation induced by sub-chronic stress

J. Leza, C. Ulecia-Morón, B. García-Bueno, 2022, Scientific reports.

Immature rat brain slices exposed to oxygen–glucose deprivation as an in vitro model of neonatal hypoxic–ischemic encephalopathy

I. Lizasoain, J. Leza, P. Lorenzo, 2005, Journal of Neuroscience Methods.

Systemic Administration of Oleoylethanolamide Protects from Neuroinflammation and Anhedonia Induced by LPS in Rats

J. Leza, F. Rodríguez de Fonseca, B. García-Bueno, 2015, The international journal of neuropsychopharmacology.

TNF–α converting enzyme (TACE) protein expression in different clinical subtypes of multiple sclerosis

I. Lizasoain, J. Leza, M. A. Moro, 2006, Journal of Neurology.

The Influence of Oxytocin and Prolactin During a First Episode of Psychosis: The Implication of Sex Differences, Clinical Features, and Cognitive Performance

J. Leza, M. Parellada, M. Bernardo, 2022, The international journal of neuropsychopharmacology.

Depressive-like States Heighten the Aversion to Painful Stimuli in a Rat Model of Comorbid Chronic Pain and Depression

J. Leza, J. Micó, E. Berrocoso, 2012, Anesthesiology.

Toll-like receptor 4 agonist and antagonist lipopolysaccharides modify innate immune response in rat brain circumventricular organs

J. Leza, B. García-Bueno, J. Madrigal, 2020, Journal of Neuroinflammation.

Severe mental illness and European COVID-19 vaccination strategies

M. Leboyer, J. Leza, J. Beezhold, 2021, The Lancet Psychiatry.

Upregulation of TACE/ADAM17 after Ischemic Preconditioning is Involved in Brain Tolerance

I. Lizasoain, A. Cárdenas, J. Leza, 2002, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

TACE/ADAM17–TNF-α Pathway in Rat Cortical Cultures after Exposure to Oxygen–Glucose Deprivation or Glutamate

O. Hurtado, I. Lizasoain, J. Leza, 2002, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Restraint stress increases neuroinflammation independently of amyloid β levels in amyloid precursor protein/PS1 transgenic mice

J. Leza, M. Heneka, M. Kummer, 2011, Journal of neurochemistry.

Expression and Functionality Study of 9 Toll-Like Receptors in 33 Drug-Naïve Non-Affective First Episode Psychosis Individuals: A 3-Month Study

J. Leza, B. Crespo-Facorro, R. Ayesa-Arriola, 2020, International journal of molecular sciences.

Noradrenaline in Alzheimer’s Disease: A New Potential Therapeutic Target

J. Leza, C. Dello Russo, B. García-Bueno, 2022, International journal of molecular sciences.

Reduced glucocorticoid receptor expression in blood mononuclear cells of patients with borderline personality disorder

J. Leza, M. Dı́az-Marsá, J. Carrasco, 2022, Frontiers in Psychiatry.

The effects of mango leaf extract during adolescence and adulthood in a rat model of schizophrenia

J. Leza, M. Desco, M. T. Fernandez-Ponce, 2022, Frontiers in Pharmacology.

TNFR1 Upregulation Mediates Tolerance after Brain Ischemic Preconditioning

O. Hurtado, A. Cárdenas, J. Leza, 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Neuroprotective effects of DETA-NONOate, a nitric oxide donor, on hydrogen peroxide-induced neurotoxicity in cortical neurones

J. Leza, P. Lorenzo, M. A. Moro, 1999, Neuropharmacology.

Endogenous cannabinoid system regulates intestinal barrier function in vivo through cannabinoid type 1 receptor activation.

J. Leza, J. Manzanares, B. García-Bueno, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Anti-inflammatory effects of Mangifera indica L. extract in a model of colitis.

J. Leza, B. García-Bueno, J. L. Madrigal, 2010, World journal of gastroenterology.

Noradrenaline induces CX3CL1 production and release by neurons

J. Leza, B. García-Bueno, J. L. Madrigal, 2017, Neuropharmacology.

The relationship between negative symptoms, social cognition, and social functioning in patients with first episode psychosis.

Lucía Albarracín García, J. Ayuso-Mateos, J. Leza, 2022, Journal of psychiatric research.

The increase in TNF-alpha levels is implicated in NF-kappaB activation and inducible nitric oxide synthase expression in brain cortex after immobilization stress.

O. Hurtado, J. Leza, P. Lorenzo, 2002, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.

Stress-induced oxidative changes in brain.

J. Leza, B. García-Bueno, J. L. Madrigal, 2006, CNS & neurological disorders drug targets.

Inducible nitric oxide synthase activity is expressed not only in inflamed but also in normal colonic mucosa in patients with ulcerative colitis: a potential prognostic marker.

J. Leza, P. Lorenzo, M. A. Moro, 2000 .

Oleoylethanolamide prevents neuroimmune HMGB1/TLR4/NF‐kB danger signaling in rat frontal cortex and depressive‐like behavior induced by ethanol binge administration

J. Leza, F. Pavón, F. Rodríguez de Fonseca, 2017, Addiction biology.

Mangiferin decreases inflammation and oxidative damage in rat brain after stress

J. Leza, B. García-Bueno, J. Madrigal, 2012, European Journal of Nutrition.

Inducible nitric oxide synthase activity is expressed not only in inflamed but also in normal colonic mucosa in patients with ulcerative colitis: a potential prognostic marker

J. Leza, P. Lorenzo, M. A. Moro, 2000, American Journal of Gastroenterology.

Changes induced by sodium cromoglycate on brain serotonin turnover in morphine dependent and abstinent mice

J. Leza, P. Lorenzo, O. San-Martin-Clark, 2005, Psychopharmacology.

Examining the immune signatures of SARS-CoV-2 infection in pregnancy and the impact on neurodevelopment: Protocol of the SIGNATURE longitudinal study

L. Fañanás, J. Leza, B. Crespo-Facorro, 2022, Frontiers in Pediatrics.

The gut-microbiota-brain axis in a Spanish population in the aftermath of the COVID-19 pandemic: microbiota composition linked to anxiety, trauma, and depression profiles

J. Leza, T. Palomo, S. Malan-Müller, 2023, Gut microbes.

Risperidone normalizes increased inflammatory parameters and restores anti-inflammatory pathways in a model of neuroinflammation.

J. Leza, C. Arango, M. Parellada, 2013, The international journal of neuropsychopharmacology.

Inflammatory and antioxidant pathway dysfunction in borderline personality disorder

J. Leza, J. Carrasco, José Villatoro, 2020, Psychiatry Research.

Chronic blockade of cannabinoid CB2 receptors induces anxiolytic‐like actions associated with alterations in GABAA receptors

J. Leza, J. Manzanares, B. García-Bueno, 2012, British journal of pharmacology.

Oxidative Stress and Inflammation in First-Episode Psychosis: A Systematic Review and Meta-analysis.

J. Leza, C. Arango, D. Fraguas, 2018, Schizophrenia bulletin.

Role of nitric oxide after brain ischaemia.

O. Hurtado, A. Cárdenas, J. Leza, 2004, Cell calcium.

Stress-induced neuroinflammation: mechanisms and new pharmacological targets.

J. Leza, C. Scavone, B. García-Bueno, 2008, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Chronic Stress Induces the Expression of Inducible Nitric Oxide Synthase in Rat Brain Cortex

J. Leza, P. Lorenzo, M. A. Moro, 2000, Journal of neurochemistry.

Morphine-induced changes in cerebral and cerebellar nitric oxide synthase activity.

J. Leza, P. Lorenzo, O. San-Martin-Clark, 1995, European journal of pharmacology.

Postnatal changes in the nitric oxide system of the rat cerebral cortex after hypoxia during delivery.

J. Leza, M. Peinado, J. López, 2003, Brain research. Developmental brain research.

Toll-like receptor 4 agonist and antagonist lipopolysaccharides modify innate immune response in rat brain circumventricular organs

J. Leza, B. García-Bueno, J. Madrigal, 2020, Journal of Neuroinflammation.

Lipid nanoparticles for antisense oligonucleotide gene interference into brain border-associated macrophages

J. Leza, A. Bortolozzi, M. Calero, 2022, Frontiers in Molecular Biosciences.

Microglial CX3CR1 production increases in Alzheimer's disease and is regulated by noradrenaline

J. Leza, D. Gómez-Garre, B. García-Bueno, 2020, Glia.

Induction of Cyclooxygenase-2 Accounts for Restraint Stress-Induced Oxidative Status in Rat Brain

J. Leza, P. Lorenzo, M. A. Moro, 2003, Neuropsychopharmacology.

Stress as a neuroinflammatory condition in brain: Damaging and protective mechanisms

J. Leza, B. García-Bueno, J. Caso, 2008, Neuroscience & Biobehavioral Reviews.

Involvement of IL-1β in acute stress-induced worsening of cerebral ischaemia in rats

Ignacio Lizasoain, Pedro Lorenzo, J. Leza, 2007, European Neuropsychopharmacology.

The Nonthiazolidinedione PPARγ Agonist L-796,449 Is Neuroprotective in Experimental Stroke

O. Hurtado, A. Cárdenas, Marta P Pereira, 2005, Journal of neuropathology and experimental neurology.

The prefrontal cortex as a target for atypical antipsychotics in schizophrenia, lessons of neurodevelopmental animal models

J. Leza, G. Flores, H. Tendilla-Beltrán, 2020, Progress in Neurobiology.

Risperidone Ameliorates Prefrontal Cortex Neural Atrophy and Oxidative/Nitrosative Stress in Brain and Peripheral Blood of Rats with Neonatal Ventral Hippocampus Lesion

J. Leza, D. Martín-Hernández, M. Tapia-Rodríguez, 2019, The Journal of Neuroscience.

Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression

J. Leza, B. García-Bueno, J. L. Madrigal, 2011, Journal of Neuroinflammation.

Gut microbiota, innate immune pathways, and inflammatory control mechanisms in patients with major depressive disorder

J. Leza, M. Carceller‐Sindreu, F. Sarramea, 2021, Translational Psychiatry.

Childhood trauma determines different clinical and biological manifestations in patients with eating disorders

J. Leza, M. Dı́az-Marsá, J. Carrasco, 2020, Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity.

Increased vulnerability to 6-hydroxydopamine lesion and reduced development of dyskinesias in mice lacking CB1 cannabinoid receptors

J. Leza, J. Manzanares, C. Ledent, 2011, Neurobiology of Aging.

Lipopolysaccharide enters the rat brain by a lipoprotein-mediated transport mechanism in physiological conditions

J. Leza, B. García-Bueno, J. Madrigal, 2017, Scientific Reports.

A Characterization of the Effects of Minocycline Treatment During Adolescence on Structural, Metabolic, and Oxidative Stress Parameters in a Maternal Immune Stimulation Model of Neurodevelopmental Brain Disorders

J. Leza, M. Desco, M. Soto-Montenegro, 2021, The international journal of neuropsychopharmacology.

Dual role of nitric oxide in adult neurogenesis

O. Hurtado, A. Cárdenas, J. Leza, 2005, Brain Research Reviews.

Chronic Mild Stress Alters Kynurenine Pathways Changing the Glutamate Neurotransmission in Frontal Cortex of Rats

J. Leza, B. García-Bueno, J. Madrigal, 2018, Molecular Neurobiology.

Glutathione Depletion, Lipid Peroxidation and Mitochondrial Dysfunction Are Induced by Chronic Stress in Rat Brain

J. Leza, P. Lorenzo, M. A. Moro, 2001, Neuropsychopharmacology.

Effects of trepelennamine on brain monoamine turnover in morphine dependent and abstinent mice

J. Leza, P. Lorenzo, O. San-Martin-Clark, 1996, Psychopharmacology.

Effects of antihistaminics on naloxone-induced withdrawal in morphine-dependent mice

J. Leza, P. Lorenzo, I. Lizasoaín, 2005, Psychopharmacology.

Effects of antihistaminics on locomotor activity in mice. Comparison with opiate and amphetamine-induced hyperactivity.

J. Leza, P. Lorenzo, I. Lizasoaín, 1991, General pharmacology.

Paliperidone Reversion of Maternal Immune Activation-Induced Changes on Brain Serotonin and Kynurenine Pathways

J. Leza, J. Meana, K. S. MacDowell, 2021, Frontiers in Pharmacology.

Buprenorphine: bell-shaped dose-response curve for its antagonist effects.

J. Leza, P. Lorenzo, I. Lizasoaín, 1991, General pharmacology.

N-(3-(aminomethyl)benzyl)acetamidine, an inducible nitric oxide synthase inhibitor, decreases colonic inflammation induced by trinitrobenzene sulphonic acid in rats.

J. Leza, P. Lorenzo, M. A. Moro, 2001, Life sciences.

Pro-/anti-inflammatory dysregulation in patients with first episode of psychosis: toward an integrative inflammatory hypothesis of schizophrenia.

J. Leza, P. Sáiz, G. Rubio, 2014, Schizophrenia bulletin.

Association Between Medication Adherence and Oxidative Stress in Patients With First-Episode Mania

J. Leza, A. González-Pinto, I. Zorrilla, 2019, Front. Psychiatry.

Behavioral, neurochemical and morphological changes induced by the overexpression of munc18-1a in brain of mice: relevance to schizophrenia

J. Leza, M. Desco, J. Pascau, 2013, Translational Psychiatry.

Corticosterone as a marker of susceptibility to oxidative/nitrosative cerebral damage after stress exposure in rats

J. Leza, B. García-Bueno, L. Menchen, 2007, Psychoneuroendocrinology.

Effects of electroconvulsive therapy in the systemic inflammatory balance of patients with severe mental disorder

J. Leza, E. Vieta, M. Bernardo, 2019, Psychiatry and clinical neurosciences.

Depletion of brain perivascular macrophages regulates acute restraint stress-induced neuroinflammation and oxidative/nitrosative stress in rat frontal cortex

J. Leza, B. García-Bueno, J. L. Madrigal, 2020, European Neuropsychopharmacology.

Building up careers in translational neuroscience and mental health research: Education and training in the Centre for Biomedical Research in Mental Health☆

L. Fañanás, J. Ayuso-Mateos, J. Leza, 2015 .

Building up careers in translational neuroscience and mental health research: Education and training in the Centre for Biomedical Research in Mental Health.

L. Fañanás, J. Ayuso-Mateos, J. Leza, 2015, Revista de psiquiatria y salud mental.

CCL2/MCP-1 modulation of microglial activation and proliferation

J. Leza, Ara E. Hinojosa, B. García-Bueno, 2011, Journal of Neuroinflammation.

Modulation of the antioxidant nuclear factor (erythroid 2-derived)-like 2 pathway by antidepressants in rats

J. Leza, B. García-Bueno, J. Madrigal, 2016, Neuropharmacology.

Expression of nitrotyrosine and oxidative consequences in the trabecular meshwork of patients with primary open-angle glaucoma.

J. Leza, B. García-Bueno, J. García-Feijóo, 2008, Investigative ophthalmology & visual science.

Peroxisome proliferator-activated receptor gamma activation decreases neuroinflammation in brain after stress in rats

J. Leza, P. Lorenzo, M. A. Moro, 2005, Biological Psychiatry.

The anti-inflammatory prostaglandin 15d-PGJ2 decreases oxidative/nitrosative mediators in brain after acute stress in rats

J. Leza, P. Lorenzo, M. A. Moro, 2005, Psychopharmacology.

Stress Increases Susceptibility to Oxidative/Nitrosative Mucosal Damage in an Experimental Model of Colitis in Rats

J. Leza, P. Lorenzo, M. A. Moro, 2004, Digestive Diseases and Sciences.

Relationship between cyclooxygenase‐2 and nitric oxide synthase‐2 in rat cortex after stress

J. Leza, P. Lorenzo, M. A. Moro, 2003, The European journal of neuroscience.

Birth Weight, Working Memory and Epigenetic Signatures in IGF2 and Related Genes: A MZ Twin Study

L. Fañanás, J. Leza, I. Nenadić, 2014, PloS one.

Comparison of the anti-inflammatory effect of aripiprazole and risperidone in 75 drug-naïve first episode psychosis individuals: A 3 months randomized study

J. Leza, B. Crespo-Facorro, M. López-Hoyos, 2018, Schizophrenia Research.

The role of tumor necrosis factor-alpha in stress-induced worsening of cerebral ischemia in rats

J. Leza, P. Lorenzo, M. A. Moro, 2006, Neuroscience.

The effects of stress on homeostasis in JCR-LA-cp rats: the role of nitric oxide.

J. Leza, M. Radomski, J. Russell, 1998, The Journal of pharmacology and experimental therapeutics.

Neuroprotection afforded by prior citicoline administration in experimental brain ischemia: effects on glutamate transport

O. Hurtado, V. Sánchez, A. Cárdenas, 2005, Neurobiology of Disease.

Plasma antioxidant capacity is reduced in Asperger syndrome.

J. Leza, C. Arango, M. Parellada, 2012, Journal of psychiatric research.

Toll-like 4 receptor inhibitor TAK-242 decreases neuroinflammation in rat brain frontal cortex after stress

J. Leza, B. García-Bueno, J. Madrigal, 2014, Journal of Neuroinflammation.

The role of BDNF and NGF plasma levels in first-episode schizophrenia: A longitudinal study

J. Leza, E. Pomarol-Clotet, M. Parellada, 2022, European Neuropsychopharmacology.

BDNF and NGF Signalling in Early Phases of Psychosis: Relationship With Inflammation and Response to Antipsychotics After 1 Year

J. Leza, P. Sáiz, A. Lobo, 2015, Schizophrenia bulletin.

Differential regulation of the TLR4 signalling pathway in post-mortem prefrontal cortex and cerebellum in chronic schizophrenia: Relationship with SP transcription factors

J. Leza, B. García-Bueno, K. S. MacDowell, 2017, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Evidence of activation of the Toll-like receptor-4 proinflammatory pathway in patients with schizophrenia.

Miguel Bernardo, Patricia Gassó, Amalia Lafuente, 2016, Journal of psychiatry & neuroscience : JPN.

The role of PPARgamma on restoration of colonic homeostasis after experimental stress-induced inflammation and dysfunction.

Ignacio Lizasoain, David Sevillano, Pedro Lorenzo, 2007, Gastroenterology.

TNF‐α accounts for short‐term persistence of oxidative status in rat brain after two weeks of repeated stress

J. Leza, P. Lorenzo, C. Scavone, 2004, The European journal of neuroscience.

Aspirin inhibits stress-induced increase in plasma glutamate, brain oxidative damage and ATP fall in rats

J. de Cristóbal, J. Leza, P. Lorenzo, 2002, Neuroreport.

The Increase in TNF-α Levels Is Implicated in NF-κB Activation and Inducible Nitric Oxide Synthase Expression in Brain Cortex after Immobilization Stress

O. Hurtado, J. Leza, P. Lorenzo, 2002, Neuropsychopharmacology.

Inducible nitric oxide synthase expression in brain cortex after acute restraint stress is regulated by nuclear factor κB‐mediated mechanisms

J. Leza, P. Lorenzo, L. Boscá, 2001, Journal of neurochemistry.

Stress induced by the socially evaluated cold-pressor test cause equivalent deficiencies of sensory gating in male subjects with schizophrenia and healthy controls

J. Leza, S. Moratti, M. Pérez-Nieto, 2015, Psychiatry Research.

Basal low antioxidant capacity correlates with cognitive deficits in early onset psychosis. A 2-year follow-up study

J. Leza, J. Castro-Fornieles, I. Baeza, 2014, Schizophrenia Research.

Neuronal and inducible nitric oxide synthase and nitrotyrosine immunoreactivities in the cerebral cortex of the aging rat

J. Leza, M. Santacana, María Angeles Peinado, 1998, Microscopy research and technique.

Role of sodium cromoglycate on analgesia, locomotor activity and opiate withdrawal in mice

J. Leza, P. Lorenzo, I. Lizasoaín, 2005, Psychopharmacology.

Changes induced by sodium cromoglycate in brain catecholamine turnover in morphine dependent and abstinent mice

J. Leza, P. Lorenzo, J. Alba, 2005, Psychopharmacology.

Calcium channel blockers: effect on morphine-induced hypermotility

J. Leza, I. Lizasoaín, M. Martín, 2005, Psychopharmacology.

H1- and H2-histamine receptor blockers and opiate analgesia in mice.

J. Leza, P. Lorenzo, I. Lizasoaín, 1990, Methods and Findings in Experimental and Clinical Pharmacology.

Polymorphisms of the IL-1 gene complex are associated with alcohol dependence in Spanish Caucasians: data from an association study.

J. Leza, J. Bobes, P. Corcoran, 2009, Alcoholism, clinical and experimental research.

Influence of psychogenetics in opiate tolerance and abstinence in mice.

J. Leza, P. Lorenzo, M. Navarro, 1991, General pharmacology.

Correlation between brain nitric oxide synthase activity and opiate withdrawal

J. Leza, P. Lorenzo, M. A. Moro, 1996, Naunyn-Schmiedeberg's Archives of Pharmacology.

Up-regulation of neuronal NO synthase immunoreactivity in opiate dependence and withdrawal

J. Leza, P. Lorenzo, M. A. Moro, 2000, Psychopharmacology.

Inhibition of morphine withdrawal by lamotrigine: involvement of nitric oxide.

J. Leza, P. Lorenzo, M. A. Moro, 1996, European Journal of Pharmacology.

Cognition and psychopathology in first-episode psychosis: are they related to inflammation?

J. Leza, J. Bobes, A. Lobo, 2016, Psychological Medicine.

Antioxidant defense system and family environment in adolescents with family history of psychosis

J. Leza, C. Arango, I. Baeza, 2012, BMC Psychiatry.

Implication of Glutamate in the Expression of Inducible Nitric Oxide Synthase After Oxygen and Glucose Deprivation in Rat Forebrain Slices

O. Hurtado, A. Cárdenas, J. Leza, 2000, Journal of neurochemistry.

Is there a role for the nuclear receptor PPARγ in neuropsychiatric diseases?

J. Leza, B. García-Bueno, B. Perez-Nievas, 2010, The international journal of neuropsychopharmacology.

The Role of the Oral Microbiota Related to Periodontal Diseases in Anxiety, Mood and Trauma- and Stress-Related Disorders

Miguel Ángel Martínez, J. Leza, C. Lowry, 2022, Frontiers in Psychiatry.

Kynurenine pathway in post-mortem prefrontal cortex and cerebellum in schizophrenia: relationship with monoamines and symptomatology

J. Leza, J. Haro, A. Ormazabal, 2021, Journal of Neuroinflammation.

Differences in the regulation of inflammatory pathways in adolescent- and adult-onset first-episode psychosis

J. Leza, P. Sáiz, A. Lobo, 2019, European Child & Adolescent Psychiatry.

Activity of Inducible and Neuronal Nitric Oxide Synthases in Colonic Mucosa Predicts Progression of Ulcerative Colitis

J. Leza, P. Lorenzo, M. A. Moro, 2004, American Journal of Gastroenterology.

Inhibition of Glutamate Release via Recovery of ATP Levels Accounts for a Neuroprotective Effect of Aspirin in Rat Cortical Neurons Exposed to Oxygen-Glucose Deprivation

J. de Cristóbal, A. Cárdenas, J. Leza, 2002, Stroke.

Intracellular inflammatory and antioxidant pathways in postmortem frontal cortex of subjects with major depression: effect of antidepressants

J. Leza, B. García-Bueno, J. Madrigal, 2018, Journal of neuroinflammation.

Implication of TNF-alpha convertase (TACE/ADAM17) in inducible nitric oxide synthase expression and inflammation in an experimental model of colitis.

O. Hurtado, J. de Cristóbal, J. Leza, 2001, Cytokine.

Inflammatory dysregulation in women with an eating disorder: Relationships with altered emotional reactivity.

J. Leza, M. Graell, M. Dı́az-Marsá, 2021, The International journal of eating disorders.

Effects of Peroxisome Proliferator-Activated Receptor Gamma Agonists on Brain Glucose and Glutamate Transporters after Stress in Rats

J. Leza, P. Lorenzo, B. García-Bueno, 2007, Neuropsychopharmacology.

Inhibition of iNOS activity by 1400W decreases glutamate release and ameliorates stroke outcome after experimental ischemia

O. Hurtado, J. Leza, P. Lorenzo, 2005, Neurobiology of Disease.

Acute effects of a session of electroconvulsive therapy on brain-derived neurotrophic factor plasma levels.

J. Leza, M. Bernardo, M. Valentí, 2020, Revista de psiquiatria y salud mental.

Early versus late stage schizophrenia. What markers make the difference?

J. Leza, J. Bobes, L. D. L. Fuente-Tomás, 2018, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

Chronic immobilisation stress ameliorates clinical score and neuroinflammation in a MOG-induced EAE in Dark Agouti rats: mechanisms implicated

J. Leza, B. García-Bueno, J. L. Madrigal, 2010, Journal of Neuroinflammation.

Functionality and Neurocognition in Patients With Bipolar Disorder After a Physical-Exercise Program (FINEXT-BD Study): Protocol of a Randomized Interventionist Program

J. Leza, I. Gorostegi-Anduaga, S. Maldonado-Martín, 2020, Frontiers in Psychiatry.

Glucocorticoid receptor gene (NR3C1) methylation processes as mediators of early adversity in stress-related disorders causality: A critical review

L. Fañanás, J. Leza, H. Palma-Gudiel, 2015, Neuroscience & Biobehavioral Reviews.

Up-regulation of TNF-α convertase (TACE/ADAM17) after oxygen–glucose deprivation in rat forebrain slices

O. Hurtado, A. Cárdenas, J. Leza, 2001, Neuropharmacology.

Therapeutic antidepressant potential of a conjugated siRNA silencing the serotonin transporter after intranasal administration

J. Leza, A. Bortolozzi, F. Artigas, 2015, Molecular Psychiatry.

Comparison of the antinociceptive effects of ibuprofen arginate and ibuprofen in rat models of inflammatory and neuropathic pain.

J. Leza, J. Micó, E. Berrocoso, 2012, Life sciences.

Protective effect of N-(3-(aminomethyl)benzyl) acetamidine, an inducible nitric oxide synthase inhibitor, in brain slices exposed to oxygen-glucose deprivation.

A. Cárdenas, J. Leza, P. Lorenzo, 1998, European journal of pharmacology.

Cannabinoid/agonist WIN 55,212‐2 reduces cardiac ischaemia–reperfusion injury in Zucker diabetic fatty rats: role of CB2 receptors and iNOS/eNOS

J. Leza, R. Abalo, B. Perez-Nievas, 2011, Diabetes/metabolism research and reviews.

Neuronal death induced by SIN-1 in the presence of superoxide dismutase: protection by cyclic GMP

J. Leza, P. Lorenzo, M. A. Moro, 1998, Neuropharmacology.

Evolution of BDNF Full-Length/Truncated Receptor Ratio and Cognitive/General Functioning After a First Episode of Psychosis

J. Leza, A. Lobo, M. Parellada, 2019, Neuropsychiatry.

Preclinical animal models of mental illnesses to translate findings from the bench to the bedside: Molecular brain mechanisms and peripheral biomarkers associated to early life stress or immune challenges

J. Leza, C. Pariante, M. Riva, 2022, European Neuropsychopharmacology.

Group B Streptococcus and E. coli LPS‐induced NO‐dependent hyporesponsiveness to noradrenaline in isolated intrapulmonary arteries of neonatal piglets

J. Leza, J. Tamargo, F. Perez-Vizcaino, 1995, British journal of pharmacology.

Analysis of Molecular Networks in the Cerebellum in Chronic Schizophrenia: Modulation by Early Postnatal Life Stressors in Murine Models

J. Leza, B. García-Bueno, K. S. MacDowell, 2021, bioRxiv.

Colonic bacterial translocation as a possible factor in stress-worsening experimental stroke outcome.

O. Hurtado, Marta P Pereira, J. Leza, 2009, American journal of physiology. Regulatory, integrative and comparative physiology.

Inflammation biomarkers in suicide attempts and their relation to abuse, global functioning and cognition

J. Leza, P. Courtet, P. Sáiz, 2021, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

Oxidative/Nitrosative Brain Damage in Stress: Possible Target for Neuropsychopharmacological Drugs

A. Cárdenas, J. Leza, P. Lorenzo, 2004 .

Effect of subacute and chronic immobilisation stress on the outcome of permanent focal cerebral ischaemia in rats

A. Cárdenas, J. Leza, P. Lorenzo, 2003, Brain Research.

Neuroinflammation and depression

J. Leza, J. Madrigal, K. S. MacDowell, 2021 .

Pro-/Antiinflammatory Dysregulation in Early Psychosis: Results from a 1-Year Follow-Up Study

J. Leza, J. Bobes, P. Sáiz, 2014, The international journal of neuropsychopharmacology.

Nitric oxide synthase activity in human squamous cell carcinoma of the head and neck

J. Leza, P. Lorenzo, M. A. Moro, 1999, The Laryngoscope.

Cognitive impairment is related to oxidative stress and chemokine levels in first psychotic episodes

J. Leza, J. Sanjuán, A. González-Pinto, 2012, Schizophrenia Research.

The effect of excess weight on circulating inflammatory cytokines in drug-naïve first-episode psychosis individuals

J. Leza, B. Crespo-Facorro, M. López-Hoyos, 2018, Journal of Neuroinflammation.

Stress Increases the Negative Effects of Chronic Pain on Hippocampal Neurogenesis

J. Leza, J. Madrigal, J. Micó, 2015, Anesthesia and analgesia.

Toward Omics-Based, Systems Biomedicine, and Path and Drug Discovery Methodologies for Depression-Inflammation Research

J. Leza, R. Balling, E. Glaab, 2016, Molecular Neurobiology.

Omega-3 fatty acids during adolescence prevent schizophrenia-related behavioural deficits: Neurophysiological evidences from the prenatal viral infection with PolyI:C

J. Leza, M. Desco, C. Arango, 2021, European Neuropsychopharmacology.

Bacterial translocation affects intracellular neuroinflammatory pathways in a depression-like model in rats

J. Leza, B. García-Bueno, J. Madrigal, 2016, Neuropharmacology.

Peripheral Endocannabinoid System Dysregulation in First-Episode Psychosis

J. Leza, P. Sáiz, A. Lobo, 2013, Neuropsychopharmacology.

Down‐Regulation of Neuronal Nitric Oxide Synthase by Nitric Oxide After Oxygen‐Glucose Deprivation in Rat Forebrain Slices

A. Cárdenas, J. Leza, P. Lorenzo, 1999, Journal of neurochemistry.

Activation of the cholinergic anti-inflammatory system in peripheral blood mononuclear cells from patients with borderline personality disorder.

J. Leza, M. Dı́az-Marsá, J. Carrasco, 2012, Journal of psychiatric research.

The anti-inflammatory prostaglandin 15d-PGJ2 and its nuclear receptor PPARgamma are decreased in schizophrenia

J. Hoenicka, J. Leza, G. Rubio, 2011, Schizophrenia Research.

How does neighbourhood socio-economic status affect the interrelationships between functioning dimensions in first episode of psychosis? A network analysis approach.

E. Baca-García, J. Leza, C. Arango, 2021, Health & place.

Fructose-1,6-bisphosphate inhibits the expression of inducible nitric oxide synthase caused by oxygen-glucose deprivation through the inhibition of glutamate release in rat forebrain slices

O. Hurtado, A. Cárdenas, J. Leza, 2000, Naunyn-Schmiedeberg's Archives of Pharmacology.

Use of brain slices in the study of pathogenic role of inducible nitric oxide synthase in cerebral ischemia-reperfusion.

A. Cárdenas, J. Leza, P. Lorenzo, 1999, General pharmacology.

Neuronal expression of inducible nitric oxide synthase after oxygen and glucose deprivation in rat forebrain slices

J. Leza, P. Lorenzo, L. Boscá, 1998, The European journal of neuroscience.

[Inflammatory/anti-inflammatory mechanisms in the brain following exposure to stress].

J. Leza, B. García-Bueno, 2008, Revista de neurología (Ed. impresa).

The effect of excess weight on circulating inflammatory cytokines in drug-naïve first-episode psychosis individuals

J. Leza, B. Crespo-Facorro, M. López-Hoyos, 2018, Journal of Neuroinflammation.

Mechanisms of the neuroprotective effect of aspirin after oxygen and glucose deprivation in rat forebrain slices

A. Cárdenas, J. Leza, P. Lorenzo, 2000, Neuropharmacology.

Alternative Method to Detect Neuronal Degeneration and Amyloid β Accumulation in Free-Floating Brain Sections With Fluoro-Jade

J. Leza, B. García-Bueno, J. L. Madrigal, 2018, ASN neuro.

COVID-19 una oportunidad única para explorar la relación entre la infección prenatal materna, el desarrollo cerebral y los trastornos neuropsiquiátricos en la descendencia

J. Leza, B. Crespo-Facorro, R. Ayesa-Arriola, 2021, Revista de psiquiatria y salud mental.

Dysfunction of inflammatory pathways in adolescent female patients with anorexia nervosa

J. Leza, M. Graell, J. Carrasco, 2020, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Neuroprotective effect of aspirin by inhibition of glutamate release after permanent focal cerebral ischaemia in rats

J. de Cristóbal, M. Colado, J. Leza, 2001, Journal of neurochemistry.

Reboxetine Treatment Reduces Neuroinflammation and Neurodegeneration in the 5xFAD Mouse Model of Alzheimer’s Disease: Role of CCL2

J. Leza, B. García-Bueno, J. L. Madrigal, 2019, Molecular Neurobiology.

Salivary secretory immunoglobulin A as a potential biomarker of psychosocial stress response during the first stages of life: A systematic review

L. Fañanás, J. Leza, H. Palma-Gudiel, 2023, Frontiers in Neuroendocrinology.

Chronic inflammation in hepatitis C patients is associated with increased perceived stress and abnormal connectivity between insula and basal ganglia

J. Leza, X. Forns, R. Navinés, 2018, European Neuropsychopharmacology.

Immune System and Brain/Intestinal Barrier Functions in Psychiatric Diseases: Is Sphingosine-1-Phosphate at the Helm?

J. Leza, B. García-Bueno, L. Menchen, 2023, International journal of molecular sciences.

Chronic immobilisation stress ameliorates clinical score and neuroinflammation in a MOG-induced EAE in Dark Agouti rats: mechanisms implicated

J. Leza, B. García-Bueno, B. Perez-Nievas, 2010, Journal of Neuroinflammation.

Discrimination between Alzheimer’s Disease and Late Onset Bipolar Disorder Using Multivariate Analysis

J. Leza, E. Echeburúa, A. González-Pinto, 2015, Front. Aging Neurosci..