M. Komatsu

发表

In vitro Cas9-assisted editing of modular polyketide synthase genes to produce desired natural product derivatives

Junko Hashimoto, Haruo Ikeda, Mamoru Komatsu, 2020, Nature Communications.

Characterization of bafilomycin biosynthesis in Kitasatospora setae KM-6054 and comparative analysis of gene clusters in Actinomycetales microorganisms

M. Nishiyama, M. Komatsu, H. Ikeda, 2017, The Journal of Antibiotics.

Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism

Satoshi Omura, Takuma Uchiyama, Haruo Ikeda, 2010, Proceedings of the National Academy of Sciences.

Cloning of the conserved regulatory operon by its aerial mycelium-inducing activity in an amfR mutant of Streptomyces griseus.

M. Komatsu, T. Beppu, K. Ueda, 2003, Gene.

An unusual extender unit is incorporated into the modular polyketide synthase of scopranones biosynthesis.

J. Hashimoto, I. Kozone, M. Komatsu, 2019, Biochemistry.

High production of a class III lantipeptide AmfS in Streptomyces griseus

M. Komatsu, H. Ikeda, K. Ueda, 2017, Bioscience, biotechnology, and biochemistry.

Discovery of Gene Cluster for Mycosporine-Like Amino Acid Biosynthesis from Actinomycetales Microorganisms and Production of a Novel Mycosporine-Like Amino Acid by Heterologous Expression

M. Komatsu, H. Ikeda, Kiyoko T. Miyamoto, 2014, Applied and Environmental Microbiology.

Amino Acid by Heterologous Expression Production of a Novel Mycosporine-Like from Actinomycetales Microorganisms and Biosynthesis Mycosporine-Like Amino Acid Discovery of Gene Cluster for

M. Komatsu, H. Ikeda, Kiyoko T. Miyamoto, 2014 .

Pleiotropic Control of Secondary Metabolism and Morphological Development by KsbC, a Butyrolactone Autoregulator Receptor Homologue in Kitasatospora setae

J. Hashimoto, M. Komatsu, H. Ikeda, 2012, Applied and Environmental Microbiology.

Genome mining in Streptomyces avermitilis: cloning and characterization of SAV_76, the synthase for a new sesquiterpene, avermitilol.

M. Komatsu, H. Ikeda, D. Cane, 2010, Journal of the American Chemical Society.

Genome mining in Streptomyces avermitilis: A biochemical Baeyer-Villiger reaction and discovery of a new branch of the pentalenolactone family tree.

M. Komatsu, H. Ikeda, D. Cane, 2009, Biochemistry.

Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol

M. Komatsu, H. Ikeda, S. Ōmura, 2008, Proceedings of the National Academy of Sciences.

Terpene synthases are widely distributed in bacteria

M. Komatsu, H. Ikeda, K. Shin‐ya, 2014, Proceedings of the National Academy of Sciences.

Engineered Streptomyces avermitilis host for heterologous expression of biosynthetic gene cluster for secondary metabolites.

Junko Hashimoto, Satoshi Omura, Yuuki Yamada, 2013, ACS synthetic biology.

The autoregulator receptor homologue AvaR3 plays a regulatory role in antibiotic production, mycelial aggregation and colony development of Streptomyces avermitilis.

M. Komatsu, H. Ikeda, S. Kitani, 2011, Microbiology.

Neothioviridamide, a Polythioamide Compound Produced by Heterologous Expression of a Streptomyces sp. Cryptic RiPP Biosynthetic Gene Cluster.

J. Hashimoto, I. Kozone, N. Kagaya, 2018, Journal of natural products.

Applied Genetics and Molecular Biotechnology

Jun Ishikawa, Takashi Matsuo, Haruo Ikeda, 2022 .

Novel thioviridamide derivative—JBIR-140: heterologous expression of the gene cluster for thioviridamide biosynthesis

J. Hashimoto, I. Kozone, N. Kagaya, 2015, The Journal of Antibiotics.

Proteins encoded by the conservon of Streptomyces coelicolor A3(2) comprise a membrane‐associated heterocomplex that resembles eukaryotic G protein‐coupled regulatory system

M. Komatsu, T. Beppu, K. Ueda, 2006, Molecular microbiology.

Pentalenic acid is a shunt metabolite in the biosynthesis of the pentalenolactone family of metabolites: hydroxylation of 1-deoxypentalenic acid mediated by CYP105D7 (SAV_7469) of Streptomyces avermitilis

M. Komatsu, H. Ikeda, D. Cane, 2011, The Journal of Antibiotics.

Modifications to central carbon metabolism in an engineered Streptomyces host to enhance secondary metabolite production.

M. Komatsu, H. Ikeda, Shiori Doi, 2020, Journal of bioscience and bioengineering.

Characterization of a silent sesquiterpenoid biosynthetic pathway in Streptomyces avermitilis controlling epi‐isozizaene albaflavenone biosynthesis and isolation of a new oxidized epi‐isozizaene metabolite

M. Komatsu, H. Ikeda, D. Cane, 2011, Microbial biotechnology.

The site-specific recombination system of actinophage TG1.

M. Komatsu, H. Ikeda, Hideo Takahashi, 2009, FEMS microbiology letters.

Outbreaks of highly pathogenic avian influenza in zoo birds caused by HA clade 2.3.4.4 H5N6 subtype viruses in Japan in winter 2016.

M. Komatsu, Toshihiro Ito, H. Ozaki, 2020, Transboundary and emerging diseases.

Site-specific genome integration in alphaproteobacteria mediated by TG1 integrase

M. Komatsu, H. Ikeda, Hideo Takahashi, 2011, Applied Microbiology and Biotechnology.

In vitro characterization of the site-specific recombination system based on actinophage TG1 integrase

M. Komatsu, H. Ikeda, Hideo Takahashi, 2009, Molecular Genetics and Genomics.

Japanese Golden Eagle Conservation Science: Current Status and Future Needs

Des B. A. Thompson, M. Komatsu, R. Ogden, 2020, Japanese Journal of Zoo and Wildlife Medicine.

tRNA-Dependent Aminoacylation of an Amino Sugar Intermediate in the Biosynthesis of a Streptothricin-Related Antibiotic

J. Hashimoto, M. Komatsu, H. Ikeda, 2016, Applied and Environmental Microbiology.

Antibiotic Overproduction by rpsL and rsmG Mutants of Various Actinomycetes

Haruo Ikeda, Mamoru Komatsu, M. Komatsu, 2009, Applied and Environmental Microbiology.

Distribution and functional analysis of the phosphopantetheinyl transferase superfamily in Actinomycetales microorganisms

Satoshi Omura, Haruo Ikeda, Mamoru Komatsu, 2018, Proceedings of the National Academy of Sciences.

Antibiotic Overproduction by rpsL and rsmG Mutants of Various Actinomycetes

M. Komatsu, H. Ikeda, A. Kaji, 2009, Applied and Environmental Microbiology.