J. Klawitter

发表

Structural identification of SAR-943 metabolites generated by human liver microsomes in vitro using mass spectrometry in combination with analysis of fragmentation patterns.

T. Strom, T. Shokati, J. Klawitter, 2011, Journal of mass spectrometry : JMS.

Bioequivalence between innovator and generic tacrolimus in liver and kidney transplant recipients: A randomized, crossover clinical trial

J. Klawitter, J. Klawitter, U. Christians, 2017, PLoS medicine.

Biomarkers in Transplantation—Proteomics and Metabolomics

J. Klawitter, J. Klawitter, U. Christians, 2016, Therapeutic drug monitoring.

Proteomics and metabolomics in renal transplantation‐quo vadis?

J. Klawitter, J. Klawitter, U. Christians, 2013, Transplant international : official journal of the European Society for Organ Transplantation.

The Role of Proteomics in the Study of Kidney Diseases and in the Development of Diagnostic Tools

J. Klawitter, J. Klawitter, U. Christians, 2011 .

Alterations in Oscillatory Behavior of Central Medial Thalamic Neurons Demonstrate a Key Role of CaV3.1 Isoform of T-Channels During Isoflurane-Induced Anesthesia.

J. Klawitter, Tamara Timic Stamenic, Simon Feseha, 2019, Cerebral cortex.

A high-performance liquid chromatography-tandem mass spectrometry-based targeted metabolomics kidney dysfunction marker panel in human urine.

J. Klawitter, J. Klawitter, U. Christians, 2015, Clinica chimica acta; international journal of clinical chemistry.

Proteo‐Metabolomic Strategies in the Future of Drug Development

J. Klawitter, J. Klawitter, U. Christians, 2012 .

CYCLOPHILIN D KNOCKOUT PROTECTS THE MOUSE KIDNEY AGAINST CYCLOSPORIN A-INDUCED OXIDATIVE STRESS.

J. Klawitter, J. Klawitter, U. Christians, 2019, American journal of physiology. Renal physiology.

Mycophenolate Mofetil Enhances the Negative Effects of Sirolimus and Tacrolimus on Rat Kidney Cell Metabolism

T. Shokati, J. Klawitter, J. Klawitter, 2014, PloS one.

Association of DJ-1/PTEN/AKT- and ASK1/p38-mediated cell signalling with ischaemic cardiomyopathy.

J. Klawitter, J. Klawitter, U. Christians, 2013, Cardiovascular research.

Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice.

J. Klawitter, U. Christians, K. Ravid, 2017, The Journal of clinical investigation.

Toxicodynamic effects of ciclosporin are reflected by metabolite profiles in the urine of healthy individuals after a single dose.

Uwe Christians, Jost Klawitter, Jelena Klawitter, 2010, British journal of clinical pharmacology.

Simultaneous Quantification of 17 Cannabinoids bY LC-MS-MS in Human Plasma.

J. Klawitter, J. Klawitter, U. Christians, 2021, Journal of analytical toxicology.

Everolimus and Sirolimus in Combination with Cyclosporine Have Different Effects on Renal Metabolism in the Rat

T. Shokati, J. Klawitter, J. Klawitter, 2012, PloS one.

Metabolic Profiles in Urine Reflect Nephrotoxicity of Sirolimus and Cyclosporine following Rat Kidney Transplantation

J. Klawitter, J. Klawitter, U. Christians, 2009, Nephron Experimental Nephrology.

Development and validation of an assay for the quantification of 11 nucleotides using LC/LC-electrospray ionization-MS.

J. Klawitter, J. Klawitter, U. Christians, 2007, Analytical biochemistry.

Endocannabinoid System in Polycystic Kidney Disease

J. Klawitter, J. Klawitter, U. Christians, 2022, American Journal of Nephrology.

Pharmacokinetics of cannabichromene in a medical cannabis product also containing cannabidiol and Δ9-tetrahydrocannabinol: a pilot study

J. Klawitter, U. Christians, M. Ware, 2021, European Journal of Clinical Pharmacology.

An Approach to Biomarker Discovery of Cannabis Use Utilizing Proteomic, Metabolomic, and Lipidomic Analyses.

J. Klawitter, U. Christians, C. Hopfer, 2020, Cannabis and cannabinoid research.

Depressed prostaglandins and leukotrienes in veterans with Gulf War illness

B. Golomb, J. Klawitter, J. Klawitter, 2019, Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.

N-Oleoyl dopamine induces IL-10 via central nervous system TRPV1 and improves endotoxemia and sepsis outcomes

J. Klawitter, K. Wilhelmsen, M. Schumacher, 2022, Journal of neuroinflammation.

Quantification of 15-F2t-isoprostane in human plasma and urine: results from enzyme-linked immunoassay and liquid chromatography/tandem mass spectrometry cannot be compared.

T. Shokati, J. Klawitter, J. Klawitter, 2011, Rapid communications in mass spectrometry : RCM.

A neurosteroid analogue with T‐type calcium channel blocking properties is an effective hypnotic, but is not harmful to neonatal rat brain

J. Klawitter, V. Jevtovic-Todorovic, S. Todorovic, 2018, British journal of anaesthesia.

Ablation of Cyclophilin D Results in an Activation of FAK, Akt, and ERK Pathways in the Mouse Heart

J. Klawitter, J. Klawitter, U. Christians, 2017, Journal of cellular biochemistry.

Everolimus and sirolimus in transplantation-related but different

J. Klawitter, U. Christians, B. Nashan, 2015, Expert opinion on drug safety.

Effects of lovastatin treatment on the metabolic distributions in the Han:SPRD rat model of polycystic kidney disease

J. Klawitter, J. Klawitter, U. Christians, 2013, BMC Nephrology.

Using Population Pharmacokinetic Modeling to Estimate Exposure to Δ9-Tetrahydrocannabinol in an Observational Study of Cannabis Smokers in Colorado

J. Klawitter, U. Christians, K. Hutchison, 2021, Therapeutic drug monitoring.

Population pharmacokinetic modeling of plasma Δ9‐tetrahydrocannabinol and an active and inactive metabolite following controlled smoked cannabis administration

J. Klawitter, U. Christians, M. Huestis, 2019, British journal of clinical pharmacology.

Disposition of Oral Cannabidiol-Rich Cannabis Extracts in Children with Epilepsy

J. Klawitter, U. Christians, M. Wempe, 2020, Clinical Pharmacokinetics.

Bone marrow-derived cPLA2α contributes to renal fibrosis progression

J. Klawitter, J. Klawitter, Seth B. Furgeson, 2017, Journal of Lipid Research.

A Metabonomic and Proteomic Analysis of Changes in IMCD3 Cells Chronically Adapted to Hypertonicity

J. Klawitter, U. Christians, T. Berl, 2008, Nephron Physiology.

Low-salt diet and cyclosporine nephrotoxicity: changes in kidney cell metabolism.

J. Klawitter, J. Klawitter, U. Christians, 2012, Journal of proteome research.

Metabolic markers for differentiation between renal allograft rejection and immunosuppressant toxicity in rat urine

J. Klawitter, J. Klawitter, U. Christians, 2017, Metabolomics.

Fatty acid desaturation index in human plasma: comparison of different analytical methodologies for the evaluation of diet effects

T. Shokati, J. Klawitter, J. Klawitter, 2014, Analytical and Bioanalytical Chemistry.

Kynurenines in polycystic kidney disease

J. Klawitter, J. Klawitter, U. Christians, 2022, Journal of Nephrology.

Development and validation of a sensitive assay for the quantification of imatinib using LC/LC-MS/MS in human whole blood and cell culture.

Yan Ling Zhang, J. Klawitter, J. Klawitter, 2009, Biomedical chromatography : BMC.

Safety and Tolerability of Cannabidiol in Parkinson Disease: An Open Label, Dose-Escalation Study.

L. Seeberger, J. Klawitter, O. Klepitskaya, 2020, Cannabis and cannabinoid research.

Development and validation of an LC-MS/MS assay for the quantification of the trans-methylation pathway intermediates S-adenosylmethionine and S-adenosylhomocysteine in human plasma.

J. Klawitter, J. Klawitter, U. Christians, 2013, Clinica chimica acta; international journal of clinical chemistry.

Analysis of 14 endocannabinoids and endocannabinoid congeners in human plasma using column switching high-performance atmospheric pressure chemical ionization liquid chromatography–mass spectrometry

L. C. Bidwell, J. Klawitter, J. Klawitter, 2021, Analytical and Bioanalytical Chemistry.

An Atmospheric Pressure Chemical Ionization MS/MS Assay Using Online Extraction for the Analysis of 11 Cannabinoids and Metabolites in Human Plasma and Urine

J. Klawitter, J. Klawitter, U. Christians, 2017, Therapeutic drug monitoring.

Absence of equilibrative nucleoside transporter 1 in ENT1 knockout mice leads to altered nucleoside levels following hypoxic challenge.

J. Klawitter, G. Sweeney, D. Choi, 2011, Life sciences.

Surface Detection of THC Attributable to Vaporizer Use in the Indoor Environment

R. Bowler, J. Klawitter, U. Christians, 2019, Scientific Reports.

Detection of Cannabinoids by LC-MS-MS and ELISA in Breast Milk.

J. Klawitter, U. Christians, T. Henthorn, 2020, Journal of analytical toxicology.

Impact of Organ Preservation Using HTK for Graft Flush and Subsequent Storage in UW in Rat Kidney Transplantation

U. Neumann, J. Klawitter, U. Christians, 2006, European Surgical Research.

Mitochondrial cyclophilin D ablation is associated with the activation of Akt/p70S6K pathway in the mouse kidney

J. Klawitter, J. Klawitter, U. Christians, 2017, Scientific Reports.

Experimental Pediatric Arterial Ischemic Stroke Model Reveals Sex-specific Estrogen Signaling

J. Klawitter, J. Klawitter, R. Traystman, 2013, Stroke.

Effects of lovastatin on breast cancer cells: a proteo-metabonomic study

T. Shokati, J. Klawitter, J. Klawitter, 2010, Breast Cancer Research.

Organ-specific response to inhibition of mitochondrial metabolism by cyclosporine in the rat

J. Klawitter, N. Serkova, C. Niemann, 2003, Transplant international : official journal of the European Society for Organ Transplantation.

Association of immunosuppressant-induced protein changes in the rat kidney with changes in urine metabolite patterns: a proteo-metabonomic study.

Uwe Christians, Jost Klawitter, Jelena Klawitter, 2010, Journal of proteome research.

Δ9-Tetrahydrocannabinol Vapor Exposure Produces Conditioned Place Preference in Male and Female Rats.

J. Klawitter, U. Christians, E. Weerts, 2022, Cannabis and cannabinoid research.

Δ9-tetrahydrocannabinol (THC) vapor exposure produces conditioned place preference in male and female rats

J. Klawitter, U. Christians, E. Weerts, 2021, bioRxiv.

A high-throughput U-HPLC-MS/MS assay for the quantification of mycophenolic acid and its major metabolites mycophenolic acid glucuronide and mycophenolic acid acyl-glucuronide in human plasma and urine.

T. Shokati, J. Klawitter, J. Klawitter, 2012, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Investigating sex differences in acute intoxication and verbal memory errors after ad libitum cannabis concentrate use.

Jarrod M. Ellingson, J. Klawitter, K. Hutchison, 2021, Drug and alcohol dependence.

Association of Naturalistic Administration of Cannabis Flower and Concentrates With Intoxication and Impairment.

Jarrod M. Ellingson, L. C. Bidwell, J. Klawitter, 2020, JAMA psychiatry.

The Role of Metabolomics in the Study of Kidney Diseases and in the Development of Diagnostic Tools

J. Klawitter, J. Klawitter, U. Christians, 2017 .

Urine metabolites reflect time-dependent effects of cyclosporine and sirolimus on rat kidney function.

Uwe Christians, Jost Klawitter, Jelena Klawitter, 2009, Chemical research in toxicology.

Assessment of tacrolimus intrapatient variability in stable adherent transplant recipients: Establishing baseline values

J. Klawitter, U. Christians, A. Vinks, 2018, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice.

J. Klawitter, U. Christians, K. Ravid, 2012, The Journal of clinical investigation.

Biomarkers of immunosuppressive drug toxicity

J. Klawitter, U. Christians, V. Schmitz, 2005 .

Biomarkers of immunosuppressant organ toxicity after transplantation: status, concepts and misconceptions

Uwe Christians, Jost Klawitter, Jelena Klawitter, 2011, Expert opinion on drug metabolism & toxicology.

Bezielle (BZL101)‐induced oxidative stress damage followed by redistribution of metabolic fluxes in breast cancer cells: A combined proteomic and metabolomic study

J. Klawitter, J. Klawitter, U. Christians, 2011, International Journal of Cancer.

Endothelial dysfunction and oxidative stress in polycystic kidney disease.

Kaleab Z. Abebe, J. Klawitter, J. Klawitter, 2014, American journal of physiology. Renal physiology.

Temsirolimus metabolic pathways revisited

T. Shokati, J. Klawitter, J. Klawitter, 2020, Xenobiotica; the fate of foreign compounds in biological systems.

Toxicodynamic Therapeutic Drug Monitoring of Immunosuppressants: Promises, Reality, and Challenges

J. Klawitter, J. Klawitter, U. Christians, 2008, Therapeutic drug monitoring.

Pravastatin Therapy and Biomarker Changes in Children and Young Adults with Autosomal Dominant Polycystic Kidney Disease.

J. Klawitter, J. Klawitter, U. Christians, 2015, Clinical journal of the American Society of Nephrology : CJASN.

Metabolic reprogramming in a slowly developing orthologous model of polycystic kidney disease.

J. Klawitter, J. Klawitter, U. Christians, 2022, American journal of physiology. Renal physiology.

Associations between Prenatal and Postnatal Exposure to Cannabis with Cognition and Behavior at Age 5 Years: The Healthy Start Study

J. Klawitter, U. Christians, D. Dabelea, 2023, International journal of environmental research and public health.

Time-dependent effects of imatinib in human leukaemia cells: a kinetic NMR-profiling study

J. Klawitter, U. Christians, D. Leibfritz, 2009, British Journal of Cancer.

Amino acids in a targeted versus a non-targeted metabolomics LC-MS/MS assay. Are the results consistent?

Uwe Christians, Jacek Klepacki, Jost Klawitter, 2016, Clinical biochemistry.

Metabolic profiling in children and young adults with autosomal dominant polycystic kidney disease

J. Klawitter, J. Klawitter, U. Christians, 2021, Scientific Reports.

Metabolic characteristics of imatinib resistance in chronic myeloid leukaemia cells

J. Klawitter, J. Klawitter, U. Christians, 2009, British journal of pharmacology.

CD73-dependent generation of adenosine and endothelial Adora2b signaling attenuate diabetic nephropathy.

J. Klawitter, U. Christians, K. Ravid, 2014, Journal of the American Society of Nephrology : JASN.

H-NMR-based metabolic signatures of mild and severe ischemia/reperfusion injury in rat kidney transplants.

Jost Klawitter, J. Klawitter, N. Serkova, 2005, Kidney international.

Kynurenines in polycystic kidney disease

J. Klawitter, J. Klawitter, U. Christians, 2022, Journal of Nephrology.

Urinary Clearance of 11-Nor-9-Carboxy-Δ9 -Tetrahydrocannabinol (THCCOOH): A Detailed Pharmacokinetic Analysis.

J. Klawitter, U. Christians, M. Huestis, 2022, Drug Testing and Analysis.

Effects of cannabidiol in cannabis flower: Implications for harm reduction

J. Klawitter, K. Hutchison, A. Bryan, 2021, Addiction biology.

How unbiased is non-targeted metabolomics and is targeted pathway screening the solution?

J. Klawitter, J. Klawitter, U. Christians, 2011, Current pharmaceutical biotechnology.

Bioactive lipid mediators in polycystic kidney disease

Kaleab Z. Abebe, J. Klawitter, J. Klawitter, 2014, Journal of Lipid Research.

Metabolic markers for differentiation between renal allograft rejection and immunosuppressant toxicity in rat urine

J. Klawitter, J. Klawitter, U. Christians, 2017, Metabolomics.

Cognitive Safety Data from a Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Phase IIb Study of the Effects of a Cannabidiol and Δ9-Tetrahydrocannabinol Drug on Parkinson's Disease-Related Motor Symptoms.

Y. Liu, J. Klawitter, S. Sillau, 2023, Movement disorders : official journal of the Movement Disorder Society.

RESEARCH PAPER Metabolic characteristics of imatinib resistance in chronic myeloid leukaemia cells

J. Klawitter, J. Klawitter, U. Christians, 2009 .

Identifying biomarkers for asthma diagnosis using targeted metabolomics approaches.

William Checkley, Robert A Wise, Uwe Christians, 2016, Respiratory medicine.

Ablation of Cyclophilin D Results in an Activation of FAK, Akt, and ERK Pathways in the Mouse Heart

J. Klawitter, J. Klawitter, U. Christians, 2017, Journal of cellular biochemistry.

Bioactive lipid mediators in polycystic kidney disease

Kaleab Z. Abebe, J. Klawitter, J. Klawitter, 2014, Journal of Lipid Research.

Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice.

J. Klawitter, U. Christians, K. Ravid, 2012, The Journal of clinical investigation.

CD73-dependent generation of adenosine and endothelial Adora2b signaling attenuate diabetic nephropathy.

J. Klawitter, U. Christians, K. Ravid, 2014, Journal of the American Society of Nephrology : JASN.

Absence of equilibrative nucleoside transporter 1 in ENT1 knockout mice leads to altered nucleoside levels following hypoxic challenge.

J. Klawitter, G. Sweeney, D. Choi, 2011, Life sciences.

Structural Identification of Zotarolimus (ABT-578) Metabolites Generated by Human Liver Microsomes Using Ion-Trap and High-Resolution Time-of-Flight Mass Spectrometry in Combination with the Analysis of Fragmentation Patterns

T. Shokati, J. Klawitter, J. Klawitter, 2023, Metabolites.

Mass Spectrometry-Based Multiplexing for the Analysis of Biomarkers in Drug Development and Clinical Diagnostics- How Much is too Much?

Uwe Christians, Jacek Klepacki, Touraj Shokati, 2012, Microchemical journal : devoted to the application of microtechniques in all branches of science.

Sex differences in endocannabinoid tone in a pilot study of cannabis use disorder and acute cannabis abstinence

J. Klawitter, Cristina Sempio, A. McRae‐Clark, 2023, Addiction biology.