R. Wooster

发表

A census of human cancer genes

T. Hubbard, M. Stratton, N. Rahman, 2004, Nature Reviews Cancer.

Instability of short tandem repeats (microsatellites) in human cancers

M. Stratton, B. Ponder, R. Wooster, 1994, Nature Genetics.

High-resolution analysis of DNA copy number using oligonucleotide microarrays.

M. Shapero, Jing Huang, K. W. Jones, 2004, Genome research.

The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website

M. Stratton, P. Futreal, R. Wooster, 2004, British Journal of Cancer.

Mutations in the DLG3 gene cause nonsyndromic X-linked mental retardation.

J. Gécz, M. Stratton, P. Futreal, 2004, American journal of human genetics.

Cancer and genomics

E. Birney, J. Mullikin, M. Stratton, 2001, Nature.

Patterns of somatic mutation in human cancer genomes

E. Birney, A. Nicholson, M. Stratton, 2007, Nature.

Breast cancer genetics: What we know and what we need

R. Wooster, B. Weber, K. Nathanson, 2001, Nature Medicine.

Identification of the breast cancer susceptibility gene BRCA2

D. Bentley, A. Ashworth, S. Seal, 1995, Nature.

Mutations of the BRAF gene in human cancer

A. Nicholson, M. Stratton, P. Futreal, 2002, Nature.

A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation

Andrew Menzies, Sarah Edkins, Sara Widaa, 2009, Nature Genetics.

Fourth International Workshop on Human Chromosome 1 Mapping 1998, Sanger Centre, Cambridge, United Kingdom, June 25-27 1998: Report

R. Wooster, S. Gregory, J. Vance, 1998 .

Breast and ovarian cancer.

R. Wooster, B. Weber, 2003, The New England journal of medicine.

Statistical Analysis of Pathogenicity of Somatic Mutations in Cancer

M. Stratton, P. Futreal, R. Wooster, 2006, Genetics.

Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13.

S. Seal, R. Wooster, S. Neuhausen, 1994, Science.

Cancer nanomedicine: progress, challenges and opportunities

P. Kantoff, R. Wooster, O. Farokhzad, 2016, Nature Reviews Cancer.

Amplification and overexpression of E2F3 in human bladder cancer

R. Wooster, R. Huddart, C. Cooper, 2004, Oncogene.

A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer

Andrew D. Yates, Yvonne R Stephens, A. Nicholson, 2005, Nature Genetics.

Athletics: Momentous sprint at the 2156 Olympics?

Andrew D. Yates, Yvonne R Stephens, A. Nicholson, 2004, Nature.

Somatic mutations of the protein kinase gene family in human lung cancer.

Andrew D. Yates, Yvonne R Stephens, A. Nicholson, 2005, Cancer research.

COSMIC 2005

M. Stratton, P. Futreal, R. Wooster, 2006, British Journal of Cancer.

Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus

M. Stratton, P. Futreal, R. Wooster, 2006, Nature Genetics.

The cancer genome project

R. Wooster, 2002 .

Sequence-based cancer genomics: progress, lessons and opportunities

Richard Wooster, Robert L. Strausberg, R. Strausberg, 2003, Nature Reviews Genetics.

A survey of RNA editing in human brain.

Richard Wooster, Matthew Blow, Michael R Stratton, 2004, Genome research.

The DNA sequence and biological annotation of human chromosome 1

I. Dunham, C. Clee, D. R. Bentley, 2006, Nature.

BRAF and RAS mutations in human lung cancer and melanoma.

Richard Wooster, Helen Davies, Michael R Stratton, 2002, Cancer research.

The V617F JAK2 mutation is uncommon in cancers and in myeloid malignancies other than the classic myeloproliferative disorders.

M. Stratton, P. Futreal, R. Wooster, 2005, Blood.

M. Stratton, P. Futreal, R. Wooster, 2002, Cancer research.

Hereditary predisposition to breast cancer.

M. Stratton, R. Wooster, Michael R. Stratton, 1996, Current opinion in genetics & development.

Genome-wide screening for complete genetic loss in prostate cancer by comparative hybridization onto cDNA microarrays

Colin Campbell, Sandra Edwards, Ian Giddings, 2003, Oncogene.

Materials and Methods with respect to the identification and sequencing of the BRCA2 cancer-suszeptilitaetsgens and its applications

Phillip Andrew Futreal, Richard Wooster, Alan Ashworth, 1996 .

Whole genome DNA copy number changes identified by high density oligonucleotide arrays

Keith W. Jones, Richard Wooster, Michael R Stratton, 2004, Human Genomics.

Mutations in ZDHHC9, which encodes a palmitoyltransferase of NRAS and HRAS, cause X-linked mental retardation associated with a Marfanoid habitus.

Andrew Menzies, Keiran Raine, Sarah Edkins, 2007, American journal of human genetics.

Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor.

Andrew Menzies, Keiran Raine, Sarah Edkins, 2007, American journal of human genetics.

Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution.

Andrew Menzies, Sarah Edkins, Richard Wooster, 2007, Genome research.

Kaposi's sarcoma-associated herpesvirus-infected primary effusion lymphoma has a plasma cell gene expression profile

Paul Kellam, Richard Wooster, Richard G. Jenner, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Genome-wide DNA copy number predictors of lapatinib sensitivity in tumor-derived cell lines

Joel Greshock, Richard Wooster, R. Wooster, 2008, Molecular Cancer Therapeutics.

Identification of the breast cancer susceptibility gene BRCA2

Julian Peto, Peter Devilee, Rosalind Eeles, 1996, Nature.

Identification of amplified and expressed genes in breast cancer by comparative hybridization onto microarrays of randomly selected cDNA clones

Colin Campbell, Sandra Edwards, Ian Giddings, 2002, Genes, chromosomes & cancer.

A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy.

Tracy T Batchelor, Richard Lugg, Andrew Menzies, 2006, Cancer research.

BRCA2 mutations in primary breast and ovarian cancers

Sheila Seal, Richard Wooster, Alan Ashworth, 1996, Nature Genetics.

Patterns of somatic mutation in human cancer genomes

E. Birney, A. Nicholson, M. Stratton, 2007, Nature.

Investigation of the molecular basis of the genetic deficiency of UDP-glucuronosyl-transferase in Crigler-Najjar syndrome

R. Wooster, B. Burchell, M. Coughtrie, 1991, Journal of Inherited Metabolic Disease.

Chromosomal assignment of human phenol and bilirubin UDP‐glucuronosyltransferase genes (UGT1A‐subfamily)

R. Wooster, S. Povey, B. Burchell, 1992, Annals of human genetics.

From chromosomes to genes: how to isolate cancer-predisposition genes

R. Wooster, 2003 .

A novel Gln358Glu mutation in ectodysplasin A associated with X‐linked dominant incisor hypodontia

T. Pemberton, P. Patel, M. Stratton, 2007, American journal of medical genetics. Part A.

Breast cancer susceptibility: a complex disease unravels.

M. Stratton, R. Wooster, M. Stratton, 1995, Trends in genetics : TIG.

The DNA sequence and biological annotation of human chromosome 1 (vol 441, pg 315, 2006)

R. Durbin, G. McVean, A. Coulson, 2006 .

Mutations in the RSK2(RPS6KA3) gene cause Coffin–Lowry syndrome and nonsyndromic X‐linked mental retardation

M. Stratton, R. Wooster, S. Edkins, 2006, Clinical genetics.

Introduction to gene structure and expression

R. Wooster, 1996 .

The BRAF gene is frequently mutated in malignant melanoma.

M. Stratton, P. Futreal, R. Wooster, 2004, Journal of drugs in dermatology : JDD.

DNA sequence analysis of known cancer genes in the NCI-60 cell lines.

J. Weinstein, M. Stratton, R. Wooster, 2006 .

Expression of a human liver cDNA encoding a UDP‐glucuronosyltransferase catalysing the glucuronidation of hyodeoxycholic acid in cell culture

M. Jackson, R. Wooster, B. Burchell, 1989, FEBS letters.

RNA editing of human microRNAs

Anton J. Enright, Richard Wooster, Michael R Stratton, 2006, Genome Biology.

A survey of homozygous deletions in human cancer genomes.

E. Birney, M. Stratton, P. Futreal, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Sequence analysis of the protein kinase gene family in human testicular germ‐cell tumors of adolescents and adults

Richard Lugg, Andrew Menzies, Keiran Raine, 2006, Genes, chromosomes & cancer.

AutoCSA, an algorithm for high throughput DNA sequence variant detection in cancer genomes

Andrew M. Jenkinson, C. Greenman, Rebecca Shepherd, 2007, Bioinform..

The BRC repeats are conserved in mammalian BRCA2 proteins.

A. Ashworth, M. Stratton, R. Wooster, 1997, Human molecular genetics.

Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13.

D. Easton, S. Seal, R. Wooster, 1995, Oncogene.

Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation

J. Gécz, M. Stratton, P. Futreal, 2007, Nature Genetics.

Molecular classification of synovial sarcomas, leiomyosarcomas and malignant fibrous histiocytomas by gene expression profiling

R. Wooster, C. Fisher, J. Clark, 2003, British Journal of Cancer.

High-content analysis of cancer genome DNA alterations.

R. Wooster, R. Lucito, S. Powers, 2008, Current opinion in genetics & development.

Cancer risks in two large breast cancer families linked to BRCA2 on chromosome 13q12-13.

D E Goldgar, D. Easton, M. Stratton, 1997, American journal of human genetics.

A germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndrome

M. Stratton, B. Ponder, R. Wooster, 1992, Nature Genetics.

The physical maps for sequencing human chromosomes 1, 6, 9, 10, 13, 20 and X

P. Deloukas, R. Durbin, J. Sulston, 2001, Nature.

Gene expression microarray analysis in cancer biology, pharmacology, and drug development: progress and potential.

R. Wooster, P. Workman, R. Wooster, 2001, Biochemical pharmacology.

Cloning, chromosomal mapping and expression pattern of the mouse Brca2 gene.

A. Ashworth, M. Stratton, R. Wooster, 1997, Human molecular genetics.

Mutation analysis of 24 known cancer genes in the NCI-60 cell line set

Richard Lugg, Andrew Menzies, Michael R. Stratton, 2006, Molecular Cancer Therapeutics.

Catalogue, cause, complexity and cure; the many uses of cancer genome sequence.

R. Wooster, K. Bachman, 2010, Current Opinion in Genetics and Development.

A genome wide linkage search for breast cancer susceptibility genes

S. Seal, M. Stratton, N. Rahman, 2006, Genes, chromosomes & cancer.

A tale of two subunits: how the neomorphic R132H IDH1 mutation enhances production of αHG.

Joseph G Boyer, R. Wooster, K. Brown, 2011, Biochemistry.

Physical mapping of the CA6, ENO1, and SLC2A5 (GLUT5) genes and reassignment of SLC2A5 to 1p36.2

R. Wooster, J. Biegel, J. Maris, 1998, Cytogenetic and Genome Research.

Somatic mutations in human cancer: insights from resequencing the protein kinase gene family.

M. Stratton, P. Futreal, R. Wooster, 2005, Cold Spring Harbor symposia on quantitative biology.

Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q

M. King, S. Seal, M. Stratton, 1994, Nature Genetics.

Rapid detection of DNA sequence variants by conformation-sensitive capillary electrophoresis.

M. Stratton, R. Wooster, N. Collins, 2000, Genomics.

Screening for ESR mutations in breast and ovarian cancer patients

A. Børresen-Dale, M. Stratton, R. Wooster, 1997, Human mutation.

Familial cylindromatosis (turban tumour syndrome) gene localised to chromosome 16q12–q13: evidence for its role as a tumour suppressor gene

M. Stratton, R. Wooster, D. Easton, 1995, Nature Genetics.

Report of the fourth international workshop on human chromosome 1 mapping 1998

R. Wooster, S. Gregory, J. Vance, 1999, Cytogenetic and Genome Research.

Characterization and primary sequence of a human hepatic microsomal estriol UDPglucuronosyltransferase.

M. Jackson, R. Wooster, M. Green, 1990, Archives of biochemistry and biophysics.

High throughput DNA sequence variant detection by conformation sensitive capillary electrophoresis and automated peak comparison.

M. Stratton, P. Futreal, R. Wooster, 2006, Genomics.

Mutations in the BRWD3 gene cause X-linked mental retardation associated with macrocephaly.

K. Friend, M. Shaw, J. Gécz, 2007, American journal of human genetics.

Microsatellite instability in human testicular germ cell tumours.

R. Wooster, A. Horwich, R. Huddart, 1995, British Journal of Cancer.

Absence of methylation of CpG dinucleotides within the promoter of the breast cancer susceptibility gene BRCA2 in normal tissues and in breast and ovarian cancers.

M. Stratton, R. Wooster, N. Collins, 1997, British Journal of Cancer.

Absence of linkage to the ataxia telangiectasia locus in familial breast cancer

B. Ponder, R. Wooster, D. Easton, 1993, Human Genetics.

The DNA sequence and biological annotation of human chromosome 1

I. Dunham, C. Clee, D. R. Bentley, 2006, Nature.

Heterozygosity for mutations in the ataxia telangiectasia gene is not a major cause of radiotherapy complications in breast cancer patients.

S. Seal, M. Stratton, N. Rahman, 1998, British Journal of Cancer.

Cloning and stable expression of a new member of the human liver phenol/bilirubin: UDP-glucuronosyltransferase cDNA family.

R. Wooster, B. Burchell, T. Ebner, 1991, The Biochemical journal.

Mutations in the gene encoding the Sigma 2 subunit of the adaptor protein 1 complex, AP1S2, cause X-linked mental retardation.

J. Gécz, M. Stratton, P. Futreal, 2006, American journal of human genetics.

The A-T gene does not make a major contribution to familial breast cancer

M. Stratton, B. Ponder, R. Wooster, 1993 .

Drug and xenobiotic glucuronidation catalysed by cloned human liver UDP-Glucuronosyltransferases stably expressed in tissue culture cell lines.

R. Wooster, B. Burchell, T. Ebner, 1993, Toxicology.

Report and abstracts of the third international workshop on human chromosome 1 mapping 1997.

T. Matise, R. Wooster, S. Gregory, 1997, Cytogenetics and cell genetics.

Sequencing analysis of BRAF mutations in human cancers.

M. Stratton, R. Wooster, A. Futreal, 2006, Methods in Enzymology.

Gene Expression Profiling after Radiation-Induced DNA Damage Is Strongly Predictive of BRCA1 Mutation Carrier Status

R. Wooster, R. Eeles, Z. Kote-Jarai, 2004, Clinical Cancer Research.

Cancer classification with DNA microarrays is less more?

R. Wooster, R Wooster, Richard Wooster, 2000, Trends in genetics : TIG.

Screening for ESR mutations in breast and ovarian cancer patients

A. Børresen-Dale, M. Stratton, R. Wooster, 1997, Human mutation.

Corrigendum: Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus

M. Stratton, P. Futreal, R. Wooster, 2011, Nature Genetics.

Mutations of the BRAF gene in human cancer

A. Nicholson, P. Futreal, R. Wooster, 2002, Nature.

Catalogue, cause, complexity and cure; the many uses of cancer genome sequence.

R. Wooster, K. Bachman, 2010, Current opinion in genetics & development.

Replacement of unfractionated heparin by low-molecular-weight heparin for postorthopedic surgery antithrombotic prophylaxis lowers the overall risk of symptomatic thrombosis because of a lower frequency of heparin-induced thrombocytopenia

P. Futreal, R. Wooster, P. Campbell, 2005 .