S. Benner

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Exhaustive matching of the entire protein sequence database.

G. Gonnet, M. Cohen, S. Benner, 1992, Science.

Patterns of divergence in homologous proteins as indicators of tertiary and quaternary structure.

S. Benner, 1989, Advances in enzyme regulation.

Predicting the conformation of proteins from sequences. Progress and future progress

S. Benner, 1995, Journal of molecular recognition : JMR.

Empirical and structural models for insertions and deletions in the divergent evolution of proteins.

G. Gonnet, M. Cohen, S. Benner, 1993, Journal of molecular biology.

Functional inferences from reconstructed evolutionary biology involving rectified databases--an evolutionarily grounded approach to functional genomics.

S. Benner, S. Govindarajan, S. G. Chamberlin, 2000, Research in microbiology.

Patterns of divergence in homologous proteins as indicators of secondary and tertiary structure: a prediction of the structure of the catalytic domain of protein kinases.

S. Benner, D. Gerloff, 1991, Advances in enzyme regulation.

Synthetic biology

S. Benner, A. M. Sismour, 2018, Springer Singapore.

Total synthesis and cloning of a gene coding for the ribonuclease S protein.

S. Benner, K. Nambiar, J. Stackhouse, 1984, Science.

An analysis of simultaneous variation in protein structures.

G. Chelvanayagam, G. Gonnet, S. Benner, 1997, Protein engineering.

The challenges of sequencing by synthesis

G. Church, T. Harris, D. Schwartz, 2009, Nature Biotechnology.

Amino acid substitution during functionally constrained divergent evolution of protein sequences.

S A Benner, G. Gonnet, M. Cohen, 1994, Protein engineering.

Multiplexed kit based on Luminex technology and achievements in synthetic biology discriminates Zika, chikungunya, and dengue viruses in mosquitoes

Kevin M. Bradley, S. Benner, K. Bradley, 2019, BMC Infectious Diseases.

Optimization of cationic (Q)-paper for detection of arboviruses in infected mosquitoes.

S. Benner, N. Burkett-Cadena, K. Wiggins, 2018, Journal of virological methods.

Detection of Mosquito-borne Arboviruses by Twenty TwoMultiplexed xMAP Luminex Arrays Panel

S. Benner, B. Alto, L. Glushakova, 2018 .

Detection of chikungunya viral RNA in mosquito bodies on cationic (Q) paper based on innovations in synthetic biology.

S. Benner, B. Alto, L. Glushakova, 2017, Journal of virological methods.

Is there a common chemical model for life in the universe?

S. Benner, M. Carrigan, A. Ricardo, 2004, Current Opinion in Chemical Biology.

Signatures of a shadow biosphere.

Carol E. Cleland, S. Benner, C. McKay, 2009, Astrobiology.

Hachimoji DNA and RNA: A genetic system with eight building blocks

Adam J. Meyer, Nicole A. Leal, S. Benner, 2019, Science.

Borate, Silicate, and Molybdate Control of Prebiotic Carbohydrate Synthesis

S. Benner, M. Carrigan, H. Kim, 2010 .

Mars Extant Life: What's Next? Conference Report

M. S. Bell, L. Matthies, R. Wiens, 2020, Astrobiology.

The missing organic molecules on Mars.

L. N. Matveeva, S. Benner, K. G. Devine, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Inferring the palaeoenvironment of ancient bacteria on the basis of resurrected proteins

S. Benner, E. Gaucher, J. Thomson, 2003, Nature.

Resurrecting ancestral alcohol dehydrogenases from yeast

S. Benner, E. Gaucher, J. Aris, 2005, Nature Genetics.

Directed evolution of polymerases to accept nucleotides with nonstandard hydrogen bond patterns.

Nicole A. Leal, S. Benner, E. Gaucher, 2013, Biochemistry.

High-throughput multiplexed xMAP Luminex array panel for detection of twenty two medically important mosquito-borne arboviruses based on innovations in synthetic biology.

Kevin M. Bradley, S. Benner, K. Bradley, 2015, Journal of virological methods.

Reconstructing the evolutionary history of the artiodactyl ribonuclease superfamily

Steven A. Benner, S. Benner, J. Stackhouse, 1995, Nature.

Hominids adapted to metabolize ethanol long before human-directed fermentation

S. Benner, M. Carrigan, T. Hurley, 2014, Proceedings of the National Academy of Sciences.

Prebiotic Chemistry that Could Not Not Have Happened

S. Benner, Hyo-Joong Kim, Elisa Biondi, 2019, Life.

Analysis of amino acid substitution during divergent evolution: the 400 by 400 dipeptide substitution matrix.

S A Benner, G. Gonnet, M. Cohen, 1994, Biochemical and biophysical research communications.

Predicting the conformation of proteins from sequences. Progress and future progress.

S A Benner, G. Gonnet, M. Cohen, 1994, Advances in enzyme regulation.

Empirical analysis of protein insertions and deletions determining parameters for the correct placement of gaps in protein sequence alignments.

Steven A Benner, S. Benner, M. Chang, 2004, Journal of molecular biology.

The Adaptive Evolution Database (TAED)

David A Liberles, Steven A Benner, S. Benner, 2001, Genome Biology.

Synthetic biology: Act natural

Steven A. Benner, S. Benner, 2003, Nature.

PCR amplification of DNA containing non-standard base pairs by variants of reverse transcriptase from Human Immunodeficiency Virus-1.

Stephen H Hughes, Stefan Lutz, Steven A Benner, 2004, Nucleic acids research.

Synthetic biology A

S. Benner, A. M. Sismour, Michael Sismour, 2005 .

Building better polymerases: Engineering the replication of expanded genetic alphabets

S. Benner, N. Richards, M. Georgiadis, 2020, The Journal of Biological Chemistry.

Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide

S. Benner, I. Singh, M. Georgiadis, 2018, Nucleic acids research.

Biological phosphorylation of an Unnatural Base Pair (UBP) using a Drosophila melanogaster deoxynucleoside kinase (DmdNK) mutant

Y. Zhang, S. Benner, S. Lutz, 2017, PloS one.

Expanded Genetic Alphabets: Managing Nucleotides That Lack Tautomeric, Protonated, or Deprotonated Versions Complementary to Natural Nucleotides.

S. Benner, M. Kim, R. Shaw, 2017, ACS synthetic biology.

A Single Deoxynucleoside Kinase Variant from Drosophila melanogaster Synthesizes Monophosphates of Nucleosides That Are Components of an Expanded Genetic System.

S. Benner, Myong-Sang Kim, Patricia Moussatche, 2017, ACS synthetic biology.

Alternative Watson-Crick Synthetic Genetic Systems.

S. Benner, Patricia Moussatche, S. Hoshika, 2016, Cold Spring Harbor perspectives in biology.

Assays To Detect the Formation of Triphosphates of Unnatural Nucleotides: Application to Escherichia coli Nucleoside Diphosphate Kinase.

S. Benner, Myong-Sang Kim, S. Hoshika, 2016, ACS synthetic biology.

Analysis of transitions at two-fold redundant sites in mammalian genomes. Transition redundant approach-to-equilibrium (TREx) distance metrics

S. Benner, S. G. Chamberlin, D. Liberles, 2006, BMC Evolutionary Biology.

Molecular paleoscience: systems biology from the past.

S. Benner, E. Gaucher, S. Sassi, 2007, Advances in enzymology and related areas of molecular biology.

Understanding Nucleic Acids Using Synthetic Chemistry.

S. Benner, 2005 .

Rearrangement of a geometrically restricted triepoxide to the first topologically nonplanar molecule: a reaction path elucidated by using oxygen isotope effects on carbon-13 chemical shifts

Steven A. Benner, Howard E. Simmons, John E. Maggio, 1981 .

Recognition of a non-standard base pair by thermostable DNA polymerases.

S. Benner, M. Lutz, J. Horlacher, 1998, Bioorganic & medicinal chemistry letters.

Synthesis of RNA containing inosine: analysis of the sequence requirements for the 5' splice site of the Tetrahymena group I intron.

S. Benner, A. Rich, R. Green, 1991, Nucleic acids research.

Evolution, language and analogy in functional genomics.

S. Benner, E. Gaucher, 2001, Trends in genetics : TIG.

When Did Life Likely Emerge on Earth in an RNA‐First Process?

S. Benner, T. Carell, S. Mojzsis, 2019, ChemSystemsChem.

Hydroxymethanesulfonate from Volcanic Sulfur Dioxide: A “Mineral” Reservoir for Formaldehyde and Other Simple Carbohydrates in Prebiotic Chemistry

S. Benner, Hyo-Joong Kim, D. C. McLendon, 2019, Astrobiology.

Molybdenum(VI)-Catalyzed Rearrangement of Prebiotic Carbohydrates in Formamide, a Candidate Prebiotic Solvent.

S. Benner, Hyo-Joong Kim, E. Ziegler, 2018, Astrobiology.

1 Setting the Stage: The History, Chemistry, and Geobiology behind RNA

S. Benner, M. Carrigan, A. Ricardo, 2006 .

Protein Structure Prediction

S. Benner, J. Rozzell, D. L. Geroff, 1996, Science.

Protein Structure Prediction

S. Benner, J. Rozzell, D. L. Geroff, 1996, Science.

Solubility of polyethers in hydrocarbons at low temperatures. A model for potential genetic backbones on warm titans.

S. Benner, F. J. Opalko, Christopher McLendon, 2015, Astrobiology.

Application of DETECTER, an evolutionary genomic tool to analyze genetic variation, to the cystic fibrosis gene family

S. Benner, E. Gaucher, Danny W De Kee, 2006, BMC Genomics.

Recognition of 2'-deoxyisoguanosine triphosphate by HIV-1 reverse transcriptase and mammalian cellular DNA polymerases.

S. Benner, M. Lutz, J. Horlacher, 1998, Bioorganic & medicinal chemistry letters.

Restriction enzymes cleave DNA immobilized on micron-sized diamond crystallites

S. Benner, Ozlem Yaren, 2015 .

Post-genomic science: converting primary structure into physiological function.

S. Benner, D. Schreiber, N. Trabesinger, 1998, Advances in enzyme regulation.

Lessons from comparative physiology: could uric acid represent a physiologic alarm signal gone awry in western society?

S. Benner, T. Nakagawa, Richard J. Johnson, 2008, Journal of Comparative Physiology B.

Tautomeric equilibria of isoguanine and related purine analogs

S. Benner, K. Khare, Robert W. Molt, 2017, Nucleosides, nucleotides & nucleic acids.

Synthesis of a monocharged peptide nucleic acid (PNA) analog and its recognition as substrate by DNA polymerases.

S. Benner, G. Breipohl, M. Lutz, 1999, Nucleosides & nucleotides.

Determination of the Absolute Configuration of Dimethyl (2S,3S)-2-Allyl-3-hydroxyglutarate: A Chiral Building Block for Preparing Branched-Chain Nucleoside Analogues

S. Benner, B. Schweizer, B. Herradón, 1993 .

pH-Independent Triple Helix Formation by an Oligonucleotide Containing a Pyrazine Donor-Donor-Acceptor Base

S. Benner, Ulrike von Krosigk, 1995 .

Agnostic Life Finder (ALF) for Large-Scale Screening of Martian Life During In Situ Refueling.

S. Benner, J. Špaček, 2022, Astrobiology.

A review: synthesis of aryl C-glycosides via the heck coupling reaction.

S. Benner, Kevin W. Wellington, 2007, Nucleosides, nucleotides & nucleic acids.

Incorporation of Multiple Sequential Pseudothymidines by DNA Polymerases and Their Impact on DNA Duplex Structure

S. Benner, Daniel Hutter, S. Hoshika, 2008, Nucleosides, nucleotides & nucleic acids.

Combining enzymatic and chemical steps in the synthesis of biochemically valuable compounds: isotopically chiral methyl acetate

S. Benner, J. Rozzell, 1983 .

Natural progression

S. Benner, 2001, Nature.

Nucleoside analogs to manage sequence divergence in nucleic acid amplification and SNP detection

Kevin M. Bradley, S. Benner, Myong-Sang Kim, 2018, Nucleic acids research.

A mechanistic basis for the stereoselectivity of enzymic transfer of hydrogen from nicotinamide cofactors

S. Benner, K. Nambiar, D. M. Stauffer, 1983 .

Stereochemical imperative in enzymic decarboxylations. Stereochemical course of the decarboxylation catalyzed by acetoacetate decarboxylase

S. Benner, J. Rozzell, 1984 .

Prebiotic plausibility and networks of paradox-resolving independent models

S. Benner, 2018, Nature Communications.

Ribonucleosides for an Artificially Expanded Genetic Information System

Nicole A. Leal, S. Benner, S. Hoshika, 2014, The Journal of organic chemistry.

Multiplexed Genetic Analysis Using an Expanded Genetic Alphabet

Eric B. Roesch, S. Benner, R. Laessig, 2004, Clinical chemistry.

PCR ampliﬁcation of DNA containing non-standard base pairs by variants of reverse transcriptase from Human Immunodeﬁciency Virus-1

S. Benner, P. Boyer, S. Hughes, 2022 .

Conversion strategy using an expanded genetic alphabet to assay nucleic acids.

Kevin M. Bradley, Nicole A. Leal, S. Benner, 2013, Analytical chemistry.

In vitro evolution of ribonucleases from expanded genetic alphabets

Kevin M. Bradley, S. Benner, S. Hoshika, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Water: Constraining Biological Chemistry and the Origin of Life

S. Benner, 2010 .

Fluorinated oil-surfactant mixtures with the density of water: Artificial cells for synthetic biology

S. Benner, Roberto Laos, 2021, bioRxiv.

Artificial genetic systems: self-avoiding DNA in PCR and multiplexed PCR.

Nicole A. Leal, S. Benner, S. Hoshika, 2010, Angewandte Chemie.

Immunosuppressive activity of angiogenin in comparison with bovine seminal ribonuclease and pancreatic ribonuclease.

S. Benner, J. Matoušek, J. Říha, 1995, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Visualizing "Alternative Isoinformational Engineered" DNA in A- and B-Forms at High Resolution.

S. Benner, M. Georgiadis, S. Hoshika, 2022, Journal of the American Chemical Society.

Polymerase Interactions with Wobble Mismatches in Synthetic Genetic Systems and Their Evolutionary Implications.

S. Benner, D. Gerloff, S. Hoshika, 2016, Biochemistry.

Frank Henry Westheimer. 15 January 1912—14 April 2007

S. Benner, E. J. Corey, 2018, BIOGRAPHICAL MEMOIRS OF FELLOWS OF THE ROYAL SOCIETY.

New Insights into Boron Essentiality in Humans and Animals

S. Benner, G. Mogoșanu, L. Bejenaru, 2022, International journal of molecular sciences.

Autonomous assembly of synthetic oligonucleotides built from an expanded DNA alphabet. Total synthesis of a gene encoding kanamycin resistance

Kevin M. Bradley, S. Benner, Daniel Hutter, 2014, Beilstein journal of organic chemistry.

Probing minor groove recognition contacts by DNA polymerases and reverse transcriptases using 3-deaza-2'-deoxyadenosine.

C. Hendrickson, S. Benner, K. G. Devine, 2004, Nucleic acids research.

Transcription, reverse transcription, and analysis of RNA containing artificial genetic components.

Steven A Benner, Shuichi Hoshika, Nicole A. Leal, 2015, ACS synthetic biology.

Artificially expanded genetic information system: a new base pair with an alternative hydrogen bonding pattern

Steven A. Benner, Zunyi Yang, Daniel Hutter, 2006, Nucleic acids research.

The use of thymidine analogs to improve the replication of an extra DNA base pair: a synthetic biological system

Steven A. Benner, S. Benner, A. M. Sismour, 2005, Nucleic acids research.

Understanding nucleic acids using synthetic chemistry.

Steven A Benner, S. Benner, 2004, Accounts of chemical research.

Recognition by viral and cellular DNA polymerases of nucleosides bearing bases with nonstandard hydrogen bonding patterns.

S. Benner, U. Hübscher, M. Hottiger, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Enzymatic recognition of the base pair between isocytidine and isoguanosine.

S A Benner, S. Benner, S. Moroney, 1993, Biochemistry.

Enzymatic incorporation of a new base pair into DNA and RNA extends the genetic alphabet

Steven A. Benner, S. Benner, J. Piccirilli, 1990, Nature.

Differential discrimination of DNA polymerase for variants of the non-standard nucleobase pair between xanthosine and 2,4-diaminopyrimidine, two components of an expanded genetic alphabet.

S. Benner, U. Hübscher, M. Hottiger, 1996, Nucleic acids research.

A Direct Route to 3‐(D‐Ribofuranosyl)pyridine Nucleosides

S. Benner, J. Piccirilli, L. Macpherson, 1991 .

Expanding the genetic alphabet: non-epimerizing nucleoside with the pyDDA hydrogen-bonding pattern.

S. Benner, Daniel Hutter, 2003, The Journal of organic chemistry.

A Direct Route to 3‐(D‐Ribofuranosyl)pyridine Nucleosides.

S. Benner, J. Piccirilli, L. Macpherson, 1991 .

A Review: Synthesis of Aryl C-Glycosides Via the Heck Coupling Reaction

S. Benner, Kevin W. Wellington, 2006 .

Fluorescent charge-neutral analogue of xanthosine: synthesis of a 2'-deoxyribonucleoside bearing a 5-aza-7-deazaxanthine base.

S. Benner, P. Rao, 2001, The Journal of organic chemistry.

Thermophile from a Mesophilic Ancestor Experimental Evolution of a Facultative

Ian K. Blaby, S. Benner, S. G. Chamberlin, 2014 .

Experimental Evolution of a Facultative Thermophile from a Mesophilic Ancestor

Ian K. Blaby, Steven A. Benner, S. Benner, 2011, Applied and Environmental Microbiology.

The Donor-Acceptor-Acceptor Purine Analog: Transformation of 5-aza-7-deaza-1H-isoguanine (=4-aminoimidazo-[1,2-a]-1,3,5-triazin-2(1H)-one) to 2′-deoxy-5-aza-7-deaza-isoguanosine using purine nucleoside phosphorylase

S. Benner, J. Voegel, M. Altorfer, 1993 .

Artificially Expanded Genetic Information Systems for New Aptamer Technologies

S. Benner, Elisa Biondi, 2018, Biomedicines.

6 Did the RNA World Exploit an Expanded Genetic Alphabet

Steven A. Benner, Petra Burgstaller, S. Benner, 1999 .

Synthesis, Molecular Recognition, and Enzymology of Oligonucleotides Containing the Non‐standard Base Pair between 5‐Aza‐7‐deazaisoguanine and 6‐Amino‐3‐methylpyrazin‐2(1H)‐one, a Donor‐Acceptor‐Acceptor Purine Analog and an Acceptor‐Donor‐Donor Pyrimidine Analog

Steven A. Benner, Johannes J. Voegel, S. Benner, 1996 .

A New Molecular Encoding System

S. Benner, Ulrike von Krosigk, J. Horlacher, 1995 .

Donor-Acceptor-Acceptor Purine Analogue: Transformation of 5-Aza-7- deaza-1H-isoguanine (= 4-Aminoimidazo(1,2-a)-1,3,5-triazin-2(1H)-one) to 2′-Deoxy-5-aza-7-deaza-isoguanosine Using Purine Nucleoside Phosphorylase.

S. Benner, J. Voegel, M. Altorfer, 1993 .

Carbocyclic analogs of nucleosides via modified Mitsunobu reactions

S. Benner, T. Jenny, N. Previsani, 1991 .

Diphenylphosphinodithioic acid: A reagent for the conversion of nitriles to thioamides

S. Benner, 1981 .

Mechanism of the reaction of diphenylphosphinodithioic acid with nitriles

S. Benner, 1981 .

Synthesis and Characterization of Non‐standard Nucleosides and Nucleotides Bearing the Acceptor‐Donor‐Donor Pyrimidine Analog 6‐Amino‐3‐methylpyrazin‐2(1H)‐one

S. Benner, J. Voegel, 1996 .

Building blocks for oligonucleotide analogues with dimethylene sulfide, sulfoxide, and sulfone groups replacing phosphodiester linkages

S. Benner, Zhen Huang, K. C. Schneider, 1991 .

C-5 Modified Nucleosides: Direct Insertion of Alkynyl-Thio Functionality in Pyrimidines

S. Benner, Abhijit Roychowdhury, H. Held, 2003, Nucleosides, nucleotides & nucleic acids.

Nonstandard Hydrogen Bonding in Duplex Oligonucleotides. The Base Pair between an Acceptor-Donor-Donor Pyrimidine Analog and a Donor-Acceptor-Acceptor Purine Analog

S. Benner, J. Voegel, 1994 .

Synthesis and tautomeric equilibrium of 6-amino-5-benzyl-3-methylpyrazin-2-one. An acceptor-donor-donor nucleoside base analog

Steven A. Benner, Johannes J. Voegel, S. Benner, 1993 .

Natural selection, protein engineering, and the last riboorganism: rational model building in biochemistry.

S. Benner, J. Piccirilli, A. Ellington, 1987, Cold Spring Harbor symposia on quantitative biology.

A Convenient Synthesis of N,N′-dibenzyl-2,4-diaminopyrimidine-2′-deoxyribonucleoside and 1-Methyl-2′-Deoxypseudoisocytidine

S. Benner, Kevin W. Wellington, H. C. Ooi, 2009, Nucleosides, nucleotides & nucleic acids.

Oligonucleotide analogs with dimethylenesulfide, -sulfoxide, and -sulfone groups replacing phosphodiester linkages.

S. Benner, Z. Huang, K. C. Schneider, 1993, Methods in molecular biology.

Synthesis and biodistribution of a short nonionic oligonucleotide analogue in mouse with a potential to mimic peptides.

S. Benner, U. Boelsterli, B. Eschgfäller, 1998, Journal of medicinal chemistry.

Crystal Structures of Two Simple N-Substituted Dihydronicotinamides: Possible Implications for Stereoelectronic Arguments in Enzymology

P. Zbinden, S. Benner, J. Dunitz, 1988 .

Four step synthesis of a 5′-deoxy-5′-iodomethylthymidine

S. Benner, C. Richert, D. Baeschlin, 1996 .

Synthesis of 2′‐Deoxyisoguanosine 5′‐Triphosphate and 2′‐Deoxy‐5‐methylisocytidine 5′‐Triphosphate

S. Benner, J. T. Kodra, Jeong Ho Park, 1999 .

Labeled Nucleoside Triphosphates with Reversibly Terminating Aminoalkoxyl Groups

Steven A. Benner, Evan Guggenheim, Visa Visalakshi, 2010, Nucleosides, nucleotides & nucleic acids.

Catalysts, Anticatalysts, and Receptors for Unactivated Phosphate Diesters in Water.

S. Benner, H. Zepik, 1999, The Journal of organic chemistry.

Comment on “The Silicate-Mediated Formose Reaction: Bottom-Up Synthesis of Sugar Silicates”

S. Benner, Hyo-Joong Kim, 2010, Science.

Planetary organic chemistry and the origins of biomolecules.

Steven A Benner, S. Benner, A. Ricardo, 2010, Cold Spring Harbor perspectives in biology.

Desorption/ionization on porous silicon mass spectrometry studies on pentose-borate complexes.

S. Benner, J. Winefordner, A. Ricardo, 2005, Analytical chemistry.

Borate Minerals Stabilize Ribose

S A Benner, S. Benner, M. Carrigan, 2004, Science.

Synthesis and Enzymology of 2'-Deoxy-7-deazaisoguanosine Triphosphate and Its Complement: A Second Generation Pair in an Artificially Expanded Genetic Information System.

Kevin M. Bradley, Nicole A. Leal, S. Benner, 2016, ACS synthetic biology.

The stereoselectivity of alcohol dehydrogenases: A sterochemical imperative?

S. Benner, 1982, Experientia.

Phosphates, DNA, and the search for nonterrean life: a second generation model for genetic molecules.

Steven A Benner, Daniel Hutter, S. Benner, 2002, Bioorganic chemistry.

Four‐Step Synthesis of a 5′‐Deoxy‐5′‐iodomethylthymidine.

S. Benner, C. Richert, D. Baeschlin, 1996 .

Oligonucleotides containing flexible nucleoside analogs

S. Benner, K. C. Schneider, K. Schneider, 1990 .

Rethinking nucleic acids from their origins to their applications

S. Benner, 2023, Philosophical Transactions of the Royal Society B.

Crystal structures of ‘ALternative Isoinformational ENgineered’ DNA in B-form

S. Benner, M. Georgiadis, S. Hoshika, 2023, Philosophical Transactions of the Royal Society B.

The "strong" RNA world hypothesis: fifty years old.

Steven A Benner, Marc Neveu, S. Benner, 2013, Astrobiology.

Eliminating primer dimers and improving SNP detection using self-avoiding molecular recognition systems

Steven A. Benner, Zunyi Yang, Daniel Hutter, 2020, Biology methods & protocols.

Optical activity due to isotopic substitution. Vibrational circular dichroism and the absolute configurations of .alpha.-deuterated cyclohexanones

S. Benner, L. Nafie, P. Polavarapu, 1981 .

The case for a Martian origin for Earth life

Steven A. Benner, Hyo-Joong Kim, S. Benner, 2015, SPIE Optical Engineering + Applications.

The exhaustive genome comparison effort. A quarter-century later

Kevin M. Bradley, S. Benner, S. Chamberlain, 2014 .

The planetary biology of cytochrome P450 aromatases

S. Benner, D. Liberles, E. Gaucher, 2004, BMC Biology.

Stereochemical Profile of the Dehydrogenases of Drosophila melanogaster

S. Benner, R. Allemann, R. Hung, 1988 .

The potential and challenges of nanopore sequencing

D. Branton, D. Deamer, D. Deamer, 2008, Nature Biotechnology.

Synthesis of carbohydrates in mineral-guided prebiotic cycles.

S. Benner, M. Carrigan, A. Ricardo, 2011, Journal of the American Chemical Society.

Adsorption of RNA on mineral surfaces and mineral precipitates

S. Benner, Elisa Biondi, J. Kawai, 2017, Beilstein journal of organic chemistry.

Evolutionary Guidance and the Engineering of Enzymes

Scott R. Presnell, S. Benner, K. Nambiar, 1986 .

Stereospecificity in Enzymology: Its Place in Evolution

S. Benner, J. Piccirilli, A. Glasfeld, 2007 .

The stereospecificity of the ferrous-ion-dependent alcohol dehydrogenase from Zymomonas mobilis.

S. Benner, A. Glasfeld, 1989, European journal of biochemistry.

Interpreting the behavior of enzymes: purpose or pedigree?

S. Benner, A. Ellington, A. Ellington, 1988, CRC critical reviews in biochemistry.

A stereochemical imperative in dehydrogenases: new data and criteria for evaluating function-based theories in bioorganic chemistry

S. Benner, K. Nambiar, G. Chambers, 1985 .

Anomeric specificity of L-fucose dehydrogenase: a stereochemical imperative in aldopyranose dehydrogenases?

S. Benner, D. Berkowitz, 1987, Biochemistry.

Free energy differences between enzyme bound states.

S. Benner, A. Ellington, 1987, Journal of theoretical biology.

Reconstructing the Evolution of Proteins

S. Benner, 1988 .

The planetary biology of ascorbate and uric acid and their relationship with the epidemic of obesity and cardiovascular disease.

S. Benner, E. Gaucher, A. Angerhofer, 2008, Medical hypotheses.

Synthesis of Oligonucleotides Containing 2′‐Deoxyisoguanosine and 2′‐Deoxy‐5‐methylisocytidine Using Phosphoramidite Chemistry

S. Benner, J. Rozzell, J. T. Kodra, 1998 .

The resurrection of ribonucleases from mammals: from ecology to medicine

S. Benner, S. Sassi, 2007 .

7 – Evolutionary Reconstructions in the Ribonuclease Family

S. Benner, M. Haugg, J. Stackhouse, 1997 .

Pseudogenes in ribonuclease evolution: a source of new biomacromolecular function?

S. Benner, G. Frank, T. Jermann, 1996, FEBS letters.

Libraries for Receptor-Assisted Combinatorial Synthesis (RACS). The Olefin Metathesis Reaction

S. Benner, S. Audétat, T. Giger, 1998 .

Expression of bovine pancreatic ribonuclease A in Escherichia coli.

Scott R. Presnell, S. Benner, K. Nambiar, 1987, European journal of biochemistry.

The return of pancreatic ribonucleases.

S. Benner, R. Allemann, 1989, Trends in biochemical sciences.

Extracellular ‘communicator RNA’

S. Benner, 1988, FEBS letters.

Synthesis, structure and activity of artificial, rationally designed catalytic polypeptides

S. Benner, K. Johnsson, R. Allemann, 1993, Nature.

Simple one-pot synthesis of a 2'-tritium labeled C-deoxynucleoside.

S. Benner, S. Lutz, 1999, Bioorganic & medicinal chemistry letters.

A C-nucleotide base pair: methylpseudouridine-directed incorporation of formycin triphosphate into RNA catalyzed by T7 RNA polymerase.

S. Benner, J. Piccirilli, S. Moroney, 1991, Biochemistry.

A Biomimetic Biotechnological Process for Converting Starch to Fructose: Thermodynamic and Evolutionary Considerations in Applied Enzymology

Steven A. Benner, S. Benner, Aydin Moradian, 1992 .

N2-Isobutyryl-O6-[2-(p-Nitrophenyl)Ethyl]Guanine: A New Building Block for the Efficient Synthesis of Carbocyclic Guanosine Analogs

S. Benner, T. Jenny, K. C. Schneider, 1992 .

Carbocyclic analogs of nucleosides. Part 2.. Synthesis of 2′,3′‐dideoxy‐5′‐homonucleoside analogs

S. Benner, T. Jenny, J. Horlacher, 1992 .

Carbocyclic Analogs of Nucleosides. Part 4.† Preparation of enantiomerically pure analogs of purine nucleosides for the synthesis of sulfone-linked oligonucleotide analogs

S. Benner, T. Jenny, 1993 .

"Skinny" and "Fat" DNA: Two New Double Helices.

Nicole A. Leal, S. Benner, I. Singh, 2018, Journal of the American Chemical Society.

Synthesis and properties of 5-cyano-substituted nucleoside analog with a donor-donor-acceptor hydrogen-bonding pattern.

S. Benner, Hyo-Joong Kim, Fei Chen, 2012, The Journal of organic chemistry.

Challenging artificial genetic systems: thymidine analogs with 5-position sulfur functionality.

S. Benner, H. Held, 2002, Nucleic acids research.

Building blocks for oligonucleotide analogs with dimethylene-sulfide, -sulfoxide, and -sulfone groups replacing phosphodiester linkages

S. Benner, K. C. Schneider, 1990 .

2'-deoxycytidines carrying amino and thiol functionality: synthesis and incorporation by Vent (exo-) polymerase.

C. Hendrickson, S. Benner, Abhijit Roychowdhury, 2004, Organic letters.

Quantitative analysis of receptors for adenosine nucleotides obtained via in vitro selection from a library incorporating a cationic nucleotide analog.

M. Bowser, S. Benner, P. Burgstaller, 1999, Journal of the American Chemical Society.

Enzymatic incorporation of a new base pair into DNA and RNA

Steven A. Benner, S. Benner, S. Moroney, 1989 .

Prebiotic stereoselective synthesis of purine and noncanonical pyrimidine nucleotide from nucleobases and phosphorylated carbohydrates

S. Benner, Hyo-Joong Kim, 2017, Proceedings of the National Academy of Sciences.

Abiotic Synthesis of Nucleoside 5'-Triphosphates with Nickel Borate and Cyclic Trimetaphosphate (CTMP).

S. Benner, Hyo-Joong Kim, 2021, Astrobiology.

Distorting Duplex DNA by Dimethylenesulfone Substitution: A New Class of “Transition State Analog” Inhibitors for Restriction Enzymes

S. Benner, A. Pingoud, C. Wenz, 1998 .

Nucleobase pairing in expanded Watson-Crick-like genetic information systems.

Steven A Benner, S. Benner, C. Geyer, 2003, Structure.

An Aptamer-Nanotrain Assembled from 6-Letter DNA Delivers Doxorubicin Selectively to Liver Cancer Cells.

S. Benner, W. Tan, Sitao Xie, 2019, Angewandte Chemie.

The challenge of synthetic biology. Synthetic Darwinism and the aperiodic crystal structure.

S. Benner, N. Karalkar, 2018, Current opinion in chemical biology.

Amplification, mutation, and sequencing of a six-letter synthetic genetic system.

Steven A Benner, Fei Chen, Zunyi Yang, 2011, Journal of the American Chemical Society.

Selective protection and deprotection procedures for thiol and hydroxyl groups

S. Benner, Zhen Huang, 1993 .

The B12-dependent ribonucleotide reductase from the archaebacterium Thermoplasma acidophila: an evolutionary solution to the ribonucleotide reductase conundrum.

S. Benner, A. Tauer, 1997, Proceedings of the National Academy of Sciences of the United States of America.

The stereospecificity of oxaloacetate decarboxylase: a stereochemical imperative?

S. Benner, J. Piccirilli, J. Rozzell, 1987 .

Crystal Structure of a Dimethylene Sulfone-Linked Ribodinucleotide Analog

S. Benner, M. Egli, A. Roughton, 1995 .

Carbocyclic Analogues of Nucleosides. Part 2. Synthesis of 2′,3′- Dideoxy-5′-homonucleoside Analogues.

S. Benner, T. Jenny, J. Horlacher, 2010 .

2'-deoxy-1-methylpseudocytidine, a stable analog of 2'-deoxy-5-methylisocytidine.

Nicole A. Leal, S. Benner, Hyo-Joong Kim, 2009, Bioorganic & medicinal chemistry.

An in vitro screening technique for DNA polymerases that can incorporate modified nucleotides. Pseudo-thymidine as a substrate for thermostable polymerases

Stefan Lutz, Steven A. Benner, Petra Burgstaller, 1999, Nucleic Acids Res..

Synthetic Biology, Tinkering Biology, and Artificial Biology. What are We Learning?

Steven A Benner, Fei Chen, Zunyi Yang, 2011, Comptes rendus. Chimie.

Synthetic Biology, Tinkering Biology, and Artificial Biology: A Perspective from Chemistry

S. Benner, Zunyi Yang, Fei Chen, 2011 .

Tautomeric Equilibria of Nucleobases in the Hachimoji Expanded Genetic Alphabet.

S. Benner, N. Richards, T. Clark, 2020, Journal of chemical theory and computation.

Biophysics of Artificially Expanded Genetic Information Systems. Thermodynamics of DNA Duplexes Containing Matches and Mismatches Involving 2-Amino-3-nitropyridin-6-one (Z) and Imidazo[1,2-a]-1,3,5-triazin-4(8H)one (P).

S. Benner, J. Kahn, R. Peterson, 2017, ACS synthetic biology.

Modern metabolism as a palimpsest of the RNA world.

S A Benner, S. Benner, A. Ellington, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Nucleoside alpha-thiotriphosphates, polymerases and the exonuclease III analysis of oligonucleotides containing phosphorothioate linkages

S. Benner, A. M. Sismour, Zunyi Yang, 2007, Nucleic acids research.

Enzymatic incorporation of a third nucleobase pair

Steven A. Benner, Zunyi Yang, S. Benner, 2007, Nucleic acids research.

Structural basis for a six nucleotide genetic alphabet.

Steven A. Benner, Isha Singh, Shuichi Hoshika, 2015, Journal of the American Chemical Society.

DNA polymerases engineered by directed evolution to incorporate non-standard nucleotides

Steven A. Benner, S. Benner, J. Thomson, 2014, Front. Microbiol..

Redesigning Genetics

S. Benner, 2004, Science.

Reverse transphosphorylation by ribonuclease A needs an intact p2-binding site. Point mutations at Lys-7 and Arg-10 alter the catalytic properties of the enzyme.

M. V. Nogués, S. Benner, C. Schein, 1994, The Journal of biological chemistry.

Electrochemical Reduction and Oxidation of Eight Unnatural 2'-Deoxynucleosides at a Pyrolytic Graphite Electrode.

S. Benner, M. Fojta, Joseph Wang, 2020, Electrochimica acta.

Crystal structures of deprotonated nucleobases from an expanded DNA alphabet.

S. Benner, K. Abboud, Hyo Joong Kim, 2016, Acta crystallographica. Section C, Structural chemistry.

Expanded genetic alphabets in the polymerase chain reaction.

Fei Chen, Steven A Benner, Zunyi Yang, 2010, Angewandte Chemie.

Guanosine derivatives bearing an N2-3-imidazolepropionic acid

S. Benner, N. Heeb, 1994 .

Is there a common chemical model for life in the universe?

S. Benner, M. Carrigan, A. Ricardo, 2004, Current opinion in chemical biology.

Engineered DNA Polymerases

S. Benner, Roberto Laos, R. Shaw, 2014 .

Phylogenomic approaches to common problems encountered in the analysis of low copy repeats: The sulfotransferase 1A gene family example

S. Benner, M. E. Bradley, 2005, BMC Evolutionary Biology.

The ribonuclease from an extinct bovid ruminant

Scott R. Presnell, S. Benner, K. Nambiar, 1990, FEBS letters.

The Natural History of Class I Primate Alcohol Dehydrogenases Includes Gene Duplication, Gene Loss, and Gene Conversion

Steven A. Benner, Thomas D. Hurley, S. Benner, 2012, PloS one.

Interpretive proteomics--finding biological meaning in genome and proteome databases.

Steven A Benner, S. Benner, 2003, Advances in enzyme regulation.

Evolution and Structural Theory: The Frontier Between Chemistry and Biology

Steven A. Benner, S. Benner, A. Ellington, 1990 .

Evaluation Measures of Multiple Sequence Alignments

Gaston H. Gonnet, Steven A. Benner, Chantal Korostensky, 2000, J. Comput. Biol..

Probabilistic Ancestral Sequences and Multiple Alignments

Gaston H. Gonnet, Steven A. Benner, G. Gonnet, 1996, SWAT.

The crystal structure of eEF1A refines the functional predictions of an evolutionary analysis of rate changes among elongation factors.

M. Miyamoto, S. Benner, E. Gaucher, 2002, Molecular biology and evolution.

Evolutionary history of the uterine serpins.

S. Benner, D. Liberles, P. Hansen, 2000, The Journal of experimental zoology.

The evolution of seminal ribonuclease: pseudogene reactivation or multiple gene inactivation events?

Steven A Benner, Edward L Braun, S. Benner, 2007, Molecular biology and evolution.

Locked nucleic acid molecular beacons.

Weihong Tan, Chaoyong James Yang, Steven A Benner, 2005, Journal of the American Chemical Society.

Dynamic assembly of primers on nucleic acid templates

Nicole A. Leal, S. Benner, M. Sukeda, 2006, Nucleic acids research.

Fourier transform-ion cyclotron resonance mass spectrometric resolution, identification, and screening of non-covalent complexes of Hck Src homology 2 domain receptor and ligands from a 324-member peptide combinatorial library

S. Benner, Weiqun Li, A. Marshall, 2002, Journal of the American Society for Mass Spectrometry.

Predicting protein crystal structures.

S A Benner, D L Gerloff, S. Benner, 1994, Science.

Predicting the conformation of proteins man versus machine

S A Benner, D L Gerloff, S. Benner, 1993, FEBS letters.

Correct structure prediction?

Mark A. Cohen, Steven A. Benner, Dietlind Gerloff, 1992, Nature.

Predicting functional divergence in protein evolution by site-specific rate shifts.

Xun Gu, Steven A Benner, Eric A Gaucher, 2002, Trends in biochemical sciences.

Bona fide prediction of aspects of protein conformation. Assigning interior and surface residues from patterns of variation and conservation in homologous protein sequences.

S A Benner, D L Gerloff, M. Cohen, 1994, Journal of molecular biology.

The Adaptive Evolution Database (TAED)

David A Liberles, Steven A Benner, S. Benner, 2001, Genome Biology.

Evolutionary, mechanistic, and predictive analyses of the hydroxymethyldihydropterin pyrophosphokinase family of proteins.

F. Cohen, S. Benner, D. Gerloff, 1999, Biochemical and biophysical research communications.

Expanding the genetic lexicon: incorporating non-standard amino acids into proteins by ribosome-based synthesis.

S A Benner, S. Benner, 1994, Trends in biotechnology.

The nitrogenase MoFe protein

S A Benner, D L Gerloff, G. Gonnet, 1993, FEBS letters.

Predicting de novo the folded structure of proteins

Steven A. Benner, S. Benner, 1992, Current Biology.

Crystal structure of a hybrid between ribonuclease A and bovine seminal ribonuclease--the basic surface, at 2.0 A resolution.

S. Benner, J. Stackhouse, K. Acharya, 1999, European journal of biochemistry.

Affinity maturation of a portable Fab–RNA module for chaperone-assisted RNA crystallography

S. Benner, J. Piccirilli, Saurja DasGupta, 2018, Nucleic acids research.

Integrating protein structures and precomputed genealogies in the Magnum database: Examples with cellular retinoid binding proteins

Steven A. Benner, Michael E. Bradley, S. Benner, 2006, BMC Bioinformatics.

Detecting compensatory covariation signals in protein evolution using reconstructed ancestral sequences.

S A Benner, S. Benner, K. Fukami-Kobayashi, 2002, Journal of molecular biology.

Planetary Biology--Paleontological, Geological, and Molecular Histories of Life

S. Benner, E. Gaucher, J. Thomson, 2002, Science.

The past as the key to the present: Resurrection of ancient proteins from eosinophils

Steven A. Benner, S. Benner, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Computational and Interpretive Genomics

Steven A. Benner, S. Benner, 2002 .

Function-structure analysis of proteins using covarion-based evolutionary approaches: Elongation factors.

M M Miyamoto, S A Benner, M. Miyamoto, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Bona Fide Predictions of Protein Secondary Structure Using Transparent Analyses of Multiple Sequence Alignments.

Marcel Turcotte, Steven A. Benner, Gina Cannarozzi, 1997, Chemical reviews.

A predicted consensus structure for the N‐Terminal fragment of the heat shock protein HSP90 family

S A Benner, F E Cohen, M Turcotte, 1997, Proteins.

Computational biochemistry research at ETH

Gaston H. Gonnet, Steven A. Benner, G. Gonnet, 1991 .

Enzyme kinetics and molecular evolution

S. Benner, 1989 .

Evolutionary, structural and biochemical evidence for a new interaction site of the leptin obesity protein.

M. Miyamoto, S. Benner, E. Gaucher, 2003, Genetics.

Reconstructed evolutionary adaptive paths give polymerases accepting reversible terminators for sequencing and SNP detection

Fei Chen, Steven A Benner, Daniel Hutter, 2010, Proceedings of the National Academy of Sciences.

Developing new synthetic catalysts. How nature does it.

S. Benner, M. Haugg, S. Raillard, 1996, Acta chemica Scandinavica.

Point of sampling detection of Zika virus within a multiplexed kit capable of detecting dengue and chikungunya

Steven A. Benner, Zunyi Yang, Kevin M. Bradley, 2017, BMC Infectious Diseases.

Uniting Natural History with the Molecular Sciences. The Ultimate Multidisciplinarity.

S. Benner, 2017, Accounts of chemical research.

Unite Efforts and Conquer Mysteries of Artificial Genetics

S. Benner, 2000, Science.

Bona Fide Predictions of Protein Secondary Structure Using Transparent Analyses of Multiple Sequence Alignments

Marcel Turcotte, Dietlind L. Gerloff, Steven A. Benner, 1998 .

Origin of dimeric structure in the ribonuclease superfamily.

S. Benner, M. Haugg, S. Raillard, 1998, Biochemistry.

Origin of the catalytic activity of bovine seminal ribonuclease against double-stranded RNA.

S. Benner, M. Haugg, S. Raillard, 1998, Biochemistry.

The design of synthetic genes.

Scott R. Presnell, S. Benner, 1988, Nucleic acids research.

In vitro selection with artificial expanded genetic information systems

Weihong Tan, Steven A. Benner, Fahong Yu, 2013, Proceedings of the National Academy of Sciences.

2-Hydroxymethylboronate as a reagent to detect carbohydrates: application to the analysis of the formose reaction.

Steven A Benner, S. Benner, M. Carrigan, 2006, The Journal of organic chemistry.

A combinatorial distance-constraint approach to predicting protein tertiary models from known secondary structure.

G Chelvanayagam, L Knecht, T Jenny, 1998, Folding & design.

Predicted secondary and supersecondary structure for the serine–threonine‐specific protein phosphatase family

S. Benner, D. Gerloff, T. Jenny, 1995, Proteins.

Interferon‐γ activates the cleavage of double‐stranded RNA by bovine seminal ribonuclease

S. Benner, C. Schein, M. Haugg, 1990 .

Planetary systems biology.

Steven A Benner, S. Benner, A. Ricardo, 2005, Molecular cell.

Theodore E. Woodward award. The evolution of obesity: insights from the mid-Miocene.

S. Benner, P. Andrews, Richard J. Johnson, 2010, Transactions of the American Clinical and Climatological Association.

Structure prediction in a post-genomic environment: a secondary and tertiary structural model for the initiation factor 5A family.

F. Cohen, S. Benner, S. G. Chamberlin, 1998, Biochemical and biophysical research communications.

Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease.

Takahiko Nakagawa, Steven Benner, Duk-Hee Kang, 2007, The American journal of clinical nutrition.

Redesigning nucleic acids

S. Benner, J. Piccirilli, K. Nambiar, 1998, Pure and applied chemistry. Chimie pure et appliquee.

2 Reading the Palimpsest: Contemporary Biochemical Data and the RNA World

G. Gonnet, S. Benner, K. Johnsson, 1993 .

Setting the stage: the history, chemistry, and geobiology behind RNA.

Steven A Benner, Zunyi Yang, S. Benner, 2012, Cold Spring Harbor perspectives in biology.

Expanding the Genetic Alphabet: Pyrazine Nucleosides That Support a Donor ? Donor ? Acceptor Hydrogen‐Bonding Pattern

S. Benner, Ulrike von Krosigk, 2004 .

Novel Biopolymers Based on an Expanded Genetic Alphabet

S. Benner, 1999 .

Site‐directed mutagenesis of bovine pancreatic ribonuclease: Lysine‐41 and aspartate‐121

S. Benner, J. Stackhouse, P. Holliger, 1991, FEBS letters.

Catalysis: design versus selection.

S A Benner, S. Benner, 1993, Science.

Abiotic regioselective phosphorylation of adenosine with borate in formamide.

S. Benner, Daniel Hutter, Hyo-Joong Kim, 2015, Astrobiology.

Nearly Forty Years after Viking: Are We Ready for a New Life-Detection Mission?

S. Benner, V. Parro, J. Rummel, 2015, Astrobiology.

Quantitative analysis of a RNA-cleaving DNA catalyst obtained via in vitro selection.

S. Benner, M. Carrigan, A. Ricardo, 2004, Biochemistry.

The NASA Astrobiology Roadmap.

David Deamer, Steven A Benner, Paul G Falkowski, 2003, Astrobiology.

Evaporite Borate-Containing Mineral Ensembles Make Phosphate Available and Regiospecifically Phosphorylate Ribonucleosides: Borate as a Multifaceted Problem Solver in Prebiotic Chemistry.

S. Benner, Hyo-Joong Kim, T. Kakegawa, 2016, Angewandte Chemie.

Structural changes to ribonuclease A and their effects on biological activity.

S. Benner, R. Raines, M. Haugg, 1999, Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology.

A Direct Prebiotic Synthesis of Nicotinamide Nucleotide.

S. Benner, Hyo-Joong Kim, 2018, Chemistry.

Mineral-Organic Interactions in Prebiotic Synthesis

S. Benner, Hyo-Joong Kim, Elisa Biondi, 2018 .

Asphalt, water, and the prebiotic synthesis of ribose, ribonucleosides, and RNA.

S. Benner, M. Carrigan, Hyo-Joong Kim, 2012, Accounts of chemical research.

APredicted Consensus Structure for the N-Terminal Fragment of the Heat Shock Protein HSP 90 Family

F. Cohen, G. Gonnet, S. Benner, 1997 .

Models and standards of proof in cross-disciplinary science: the case of arsenic DNA.

Sara Seager, William Bains, Steven A Benner, 2013, Astrobiology.

Opal Adsorbs and Stabilizes RNA – A Hierarchy of Prebiotic Silica Minerals

S. Benner, Elisa Biondi, Layne Howell, 2016, Synlett.

Chemical Guidance in the Search for Past and Extant Life on Mars

Steven A. Benner, Elisa Biondi, Hyo-Joong Kim, 2020, 2009.00723.

A predicted consensus structure for the C terminus of the beta and gamma chains of fibrinogen

F. Cohen, S. Benner, D. Gerloff, 1997, Proteins.

The phospho‐β‐galactosidase and synaptotagmin predictions

Dietlind L. Gerloff, Steven A. Benner, G. Chelvanayagam, 1995 .

A predicted consensus structure for the protein kinase C2 homology (C2H) domain, the repeating unit of synaptotagmin

G Chelvanayagam, S A Benner, D L Gerloff, 1995, Proteins.

A consensus prediction of the secondary structure for the 6‐phospho‐β‐D‐galactosidase superfamily

S. Benner, D. Gerloff, 1995, Proteins.

A prediction of the secondary structure of the pleckstrin homology domain

S A Benner, S. Benner, T F Jenny, 1994, Proteins.

A secondary structure prediction of the hemorrhagic metalloprotease family.

S. Benner, L. Knecht, D. Gerloff, 1993, Biochemical and biophysical research communications.

Predicted secondary structure for the Src homology 3 domain.

S A Benner, M. Cohen, S. Benner, 1993, Journal of molecular biology.

Ultra-rapid detection of SARS-CoV-2 in public workspace environments

Kevin M. Bradley, O. Yaren, J. McCarter, 2020, medRxiv.

Defining life.

S. Benner, 2010, Astrobiology.

Confluence of Theory and Experiment Reveal the Catalytic Mechanism of the Varkud Satellite Ribozyme

Timothy J. Giese, S. Benner, D. York, 2019, Nature Chemistry.

DNA Structure Design Is Improved Using an Artificially Expanded Alphabet of Base Pairs Including Loop and Mismatch Thermodynamic Parameters

D. Mathews, S. Benner, J. Kahn, 2023, bioRxiv.

Oligodeoxyribonucleotide analogues with bridging dimethylene sulfide, sulfoxide, and sulfone groups. Toward a second-generation model of nucleic acid structure.

S. Benner, Zhen Huang, 2002, Journal of Organic Chemistry.

Nonionic Analogs of RNA with Dimethylene Sulfone Bridges

S. Benner, A. Roughton, C. Richert, 1996 .

Synthesis as a Route to Knowledge

S. Benner, 2013, Biological Theory.

Recombinase‐Based Isothermal Amplification of Nucleic Acids with Self‐Avoiding Molecular Recognition Systems (SAMRS)

Kevin M. Bradley, S. Benner, Daniel Hutter, 2014, Chembiochem : a European journal of chemical biology.

Self-Avoiding Molecular Recognition Systems (SAMRS).

Nicole A. Leal, S. Benner, S. Hoshika, 2008, Nucleic Acids Symposium Series.

A word in your protein

Gaston H. Gonnet, Steven A. Benner, G. Gonnet, 1993, Nature.

Deducing the Composition of Venus Cloud Particles with the Autofluorescence Nephelometer (AFN)

S. Benner, D. Baumgardner, P. Zmarzly, 2022, Aerospace.

Protein Structure Prediction

S A Benner, S. Benner, D L Geroff, 1996, Science.

Synthesis and Properties of Oligodeoxynucleotide Analogs with Bis(methylene) Sulfone Bridges

S. Benner, Jurgen G Schmidt, B. Eschgfäller, 2003 .

Evolution of functional six-nucleotide DNA.

Kevin M. Bradley, S. Benner, W. Tan, 2015, Journal of the American Chemical Society.

X-ray crystal structure of a dimethylene sulfone-bridged ribonucleotide dimer in a single-stranded state

Martin Egli, Steven A. Benner, Clemens Richert, 1995, Nucleic Acids Res..

Catalytic Synthesis of Polyribonucleic Acid on Prebiotic Rock Glasses

S. Benner, S. Mojzsis, Hyo-Joong Kim, 2022, Astrobiology.

A Strategy for Origins of Life Research

N. Packard, T. Ikegami, S. Benner, 2015, Astrobiology.

Synthesis of Pyrophosphates for In Vitro Selection of Catalytic RNA Molecules

S. Benner, Daniel Hutter, N. Karalkar, 2008, Nucleosides, nucleotides & nucleic acids.

Prebiotic glycosylation of uracil with electron-donating substituents.

S. Benner, Hyo-Joong Kim, 2015, Astrobiology.

The early days of paleogenetics: connecting molecules to the planet

S. Benner, 2007 .

Aesthetics in synthesis and synthetic biology.

S. Benner, 2012, Current opinion in chemical biology.

Design of a novel molecular beacon: modification of the stem with artificially genetic alphabet.

Weihong Tan, Steven A Benner, Zunyi Yang, 2008, Chemical communications.

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1.

Kevin M. Bradley, S. Benner, B. Alto, 2018, Journal of visualized experiments : JoVE.

Old Views of Ancient Events

S. Benner, 1999, Science.

Recognition of an expanded genetic alphabet by type-II restriction endonucleases and their application to analyze polymerase fidelity

Fei Chen, Steven A. Benner, Zunyi Yang, 2011, Nucleic acids research.

"Progenote" or "protogenote"?

S. Benner, A. Ellington, 1990, Science.

Ligand Guided Selection (LIGS) with Artificially Expanded Genetic Information Systems against TCR-CD3ε.

Steven Benner, Nicole Williams, Zunyi Yang, 2019, Biochemistry.

A Crystal Structure of a Functional RNA Molecule Containing an Artificial Nucleobase Pair.

Steven A Benner, Zunyi Yang, Shuichi Hoshika, 2015, Angewandte Chemie.

Synthesis, Molecular Recognition, and Enzymology of Oligonucleotides Containing the Non‐Standard Base Pair Between 5‐Aza‐7‐deazaisoguanine and 6‐Amino‐3‐methylpyrazin‐2(1H)‐one, a Donor‐Acceptor‐Acceptor Purine Analogue and an Acceptor‐Donor‐Donor Pyrimidine Analogue.

S. Benner, J. Voegel, 1997 .

Detecting respiratory viral RNA using expanded genetic alphabets and self-avoiding DNA

Kevin M. Bradley, S. Benner, L. Glushakova, 2015, Analytical Biochemistry.

Detecting Darwinism from Molecules in the Enceladus Plumes, Jupiter's Moons, and Other Planetary Water Lagoons

Steven A. Benner, S. Benner, 2017, Astrobiology.

Engineering yeast alcohol dehydrogenase. Replacing Trp54 by Leu broadens substrate specificity.

S. Benner, E. Weinhold, 1995, Protein engineering.

Life after the synthetic cell

Martin Fussenegger, Steen Rasmussen, Jim Collins, 2010, Nature.

Assessing Readability of an 8-Letter Expanded Deoxyribonucleic Acid Alphabet with Nanopores.

S. Benner, Christopher M Thomas, J. Gundlach, 2023, Journal of the American Chemical Society.

A norovirus detection architecture based on isothermal amplification and expanded genetic systems.

Kevin M. Bradley, S. Benner, Patricia Moussatche, 2016, Journal of virological methods.

Laboratory evolution of artificially expanded DNA gives redesignable aptamers that target the toxic form of anthrax protective antigen

Steven A. Benner, Elisa Biondi, Shuichi Hoshika, 2016, Nucleic acids research.

Aptamers against Cells Overexpressing Glypican 3 from Expanded Genetic Systems Combined with Cell Engineering and Laboratory Evolution.

Kevin M. Bradley, S. Benner, W. Tan, 2016, Angewandte Chemie.

Standard and AEGIS nicking molecular beacons detect amplicons from the Middle East respiratory syndrome coronavirus

Kevin M. Bradley, S. Benner, L. Glushakova, 2016, Journal of Virological Methods.

Dynamic transduction of energy and internal equilibria in enzymes: a reexamination of pyruvate kinase

S. Benner, K. Nambiar, J. Stackhouse, 1985 .

Helicase‐Dependent Isothermal Amplification of DNA and RNA by Using Self‐Avoiding Molecular Recognition Systems

Kevin M. Bradley, S. Benner, Daniel Hutter, 2015, Chembiochem : a European journal of chemical biology.

Nicotinamide Riboside, a Promising Vitamin B3 Derivative for Healthy Aging and Longevity: Current Research and Perspectives

S. Benner, G. Mogoșanu, L. Bejenaru, 2023, Molecules.

The last ribo-organism

S. Benner, A. Ellington, 1987, Nature.

Artificial genetic systems: exploiting the "aromaticity" formalism to improve the tautomeric ratio for isoguanosine derivatives.

Steven A Benner, Theodore A. Martinot, S. Benner, 2004, The Journal of organic chemistry.

Synthetic Biology Pathway to Nucleoside Triphosphates for Expanded Genetic Alphabets.

S. Benner, P. Marlière, M. Kim, 2023, ACS synthetic biology.

A hybrid of bovine pancreatic ribonuclease and human angiogenin: an external loop as a module controlling substrate specificity?

Scott R. Presnell, S. Benner, R. Allemann, 1991, Protein engineering.

The Nature of Life: Classical and Contemporary Perspectives from Philosophy and Science: Is there a common chemical model for life in the universe?

S. Benner, M. Carrigan, A. Ricardo, 2010 .

Unusual Hydrogen Bonding Patterns and the Role of the Backbone in Nucleic Acid Information Transfer

S. Benner, 2016, ACS central science.

An improved system for expressing pancreatic ribonuclease in Escherichia coli

S. Benner, G. McGeehan, 1989, FEBS letters.

The role of thrifty genes in the origin of alcoholism: A narrative review and hypothesis.

S. Benner, M. Lanaspa, R. Dudley, 2021, Alcoholism, clinical and experimental research.

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1.

Kevin M. Bradley, S. Benner, B. Alto, 2018, Journal of visualized experiments : JoVE.

Aptamers against Cells Overexpressing Glypican 3 from Expanded Genetic Systems Combined with Cell Engineering and Laboratory Evolution.

Kevin M. Bradley, S. Benner, W. Tan, 2016, Angewandte Chemie.

Experimental Evolution of a Facultative Thermophile from a Mesophilic Ancestor

Ian K. Blaby, S. Benner, V. de Crécy-Lagard, 2011, Applied and Environmental Microbiology.

Body temperature and the specific heat of water

S. Benner, J. Dunitz, 1986, Nature.

Synthesis as a Route to Knowledge

S. Benner, 2013 .

Synthetic Biology, Tinkering Biology, and Artificial Biology. What are We Learning?

S. Benner, Zunyi Yang, Fei Chen, 2011, Comptes rendus. Chimie.

A Direct Synthesis of Nucleoside Analogs Homologated at the 3′‐ and 5′‐Positions

S. Benner, Jurgen G Schmidt, Bernd Eschgfäller, 2003 .

Synthesis and Properties of Oligodeoxynucleotide Analogs with Bis(methylene) Sulfone Bridges

S. Benner, Jurgen G Schmidt, M. König, 2003 .

Building Blocks for Oligonucleotide Analogues with Dimethylene Sulfide, Sulfoxide, and Sulfone Group Replacing Phosphodiester Linkages.

S. Benner, Zhen Huang, K. Schneider, 1991 .

Aesthetics in synthesis and synthetic biology.

S. Benner, 2012, Current opinion in chemical biology.

S. Benner, J. Kahn, R. Peterson, 2017, ACS synthetic biology.

Recognition of Uncharged Polyamide-Linked Nucleic Acid Analogs by DNA Polymerases and Reverse Transcriptases

Gerhard Breipohl, Eugen Uhlmann, Steven A. Benner, 1997 .

Structure and Biophysics for a Six Letter DNA Alphabet that Includes Imidazo[1,2-a]-1,3,5-triazine-2(8H)-4(3H)-dione (X) and 2,4-Diaminopyrimidine (K).

S. Benner, I. Singh, M. Georgiadis, 2017, ACS synthetic biology.

Synthesis of carbohydrates in mineral-guided prebiotic cycles.

S. Benner, M. Carrigan, A. Ricardo, 2011, Journal of the American Chemical Society.