H. Khorana

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Bacteriorhodopsin, a membrane protein that uses light to translocate protons.

H. Khorana, 1988, The Journal of biological chemistry.

Transmembrane protein structure: spin labeling of bacteriorhodopsin mutants.

H. Khorana, C. Altenbach, W. Hubbell, 1990, Science.

Studies on polynucleotides. XCVI. Repair replications of short synthetic DNA's as catalyzed by DNA polymerases.

H. Khorana, I. Molineux, E. Ohtsuka, 1971, Journal of molecular biology.

Studies on Polynucleotides. XXIV.1 The Stepwise Synthesis of Specific Deoxyribopolynucleotides (4).2 Protected Derivatives of Deoxyribonucleosides and New Syntheses of Deoxyribonucleoside-3″ Phosphates3

H. Khorana, G. Weimann, H. Schaller, 1963 .

Structure and function in rhodopsin: Asymmetric reconstitution of rhodopsin in liposomes

H. Khorana, L. Niu, Jong-Myoung Kim, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Escherichia coli tyrosine transfer ribonucleic acid genes. Nucleotide sequences of their promoters and of the regions adjoining C-C-A ends.

R. Contreras, H. Khorana, A. Landy, 1976, The Journal of biological chemistry.

Requirement of Rigid-Body Motion of Transmembrane Helices for Light Activation of Rhodopsin

H. Khorana, C. Altenbach, W. Hubbell, 1996, Science.

Orientation of retinal in bovine rhodopsin determined by cross-linking using a photoactivatable analog of 11-cis-retinal.

H. Khorana, H G Khorana, T A Nakayama, 1990, The Journal of biological chemistry.

Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: a site-directed spin-labeling study.

H. Khorana, C. Altenbach, W. Hubbell, 1996, Biochemistry.

Structure and function in rhodopsin: mapping light-dependent changes in distance between residue 65 in helix TM1 and residues in the sequence 306-319 at the cytoplasmic end of helix TM7 and in helix H8.

J. Klein-Seetharaman, H. Khorana, C. Altenbach, 2001, Biochemistry.

Structure and function in rhodopsin: High-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line

Roland Contreras, Nico Callewaert, Philip J. Reeves, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Opsin stability and folding: modulation by phospholipid bicelles.

H Gobind Khorana, H. Khorana, B. Wallace, 2007, Journal of molecular biology.

Structure and function in rhodopsin: the role of asparagine-linked glycosylation.

S. Kaushal, H. Khorana, K. Ridge, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Opsin is present as dimers in COS1 cells: identification of amino acids at the dimeric interface.

H. Khorana, P. Reeves, U. RajBhandary, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Phospholipids Containing Photoactivable Groups in Studies of Biological Membranes *

H. Khorana, B. Erni, R. Radhakrishnan, 1980, Annals of the New York Academy of Sciences.

Assembly of functional rhodopsin requires a disulfide bond between cysteine residues 110 and 187.

H. Khorana, S. Karnik, S. Karnik, 1990, The Journal of biological chemistry.

NMR spectroscopy in studies of light-induced structural changes in mammalian rhodopsin: applicability of solution (19)F NMR.

J. Klein-Seetharaman, H. Khorana, P. Reeves, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Structure-function studies on bacteriorhodopsin. I. Expression of the bacterio-opsin gene in Escherichia coli.

H. Khorana, N. Hackett, K. Kimura, 1987, The Journal of biological chemistry.

Expression of a synthetic bovine rhodopsin gene in monkey kidney cells.

H. Khorana, D. Oprian, R. Molday, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Structure of the interhelical loops and carboxyl terminus of bacteriorhodopsin by X-ray diffraction using site-directed heavy-atom labeling.

H. Khorana, M. P. Heyn, R. Mollaaghababa, 1998, Biochemistry.

Cysteine residues 110 and 187 are essential for the formation of correct structure in bovine rhodopsin.

H. Khorana, T. Sakmar, S. Karnik, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Structure and function in rhodopsin: replacement by alanine of cysteine residues 110 and 187, components of a conserved disulfide bond in rhodopsin, affects the light-activated metarhodopsin II state.

H. Khorana, F. Davidson, P. Loewen, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Carbodiimides. VIII.1 Observations on the Reactions of Carbodiimides with Acids and Some New Applications in the Synthesis of Phosphoric Acid Esters

J. G. Moffatt, H. Khorana, Michael Smith, 1958 .

Single-cysteine substitution mutants at amino acid positions 306-321 in rhodopsin, the sequence between the cytoplasmic end of helix VII and the palmitoylation sites: sulfhydryl reactivity and transducin activation reveal a tertiary structure.

J. Klein-Seetharaman, H. Khorana, C. Altenbach, 1999, Biochemistry.

The Roles of Transmembrane Domain Helix-III during Rhodopsin Photoactivation

H. Khorana, W. Ou, Jong-Myoung Kim, 2011, PloS one.

Studies on Polynucleotides. XXXIV.1 The Specific Synthesis of C3'-C5'-Linked Ribooligonucleotides.2 New Protected Derivatives of Ribonucleosides and Ribonucleoside 3'-Phosphates. Further Syntheses of Diribonucleoside Phosphates3

H. Khorana, R. Lohrmann, 1964 .

Light-driven activation of beta 2-adrenergic receptor signaling by a chimeric rhodopsin containing the beta 2-adrenergic receptor cytoplasmic loops.

Pere Garriga, H Gobind Khorana, H. Khorana, 2005, Biochemistry.

Nucleotide sequence in the promoter region of the Escherichia coli tyrosine tRNA gene.

H. Khorana, T. Sekiya, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Protonation state of Asp (Glu)-85 regulates the purple-to-blue transition in bacteriorhodopsin mutants Arg-82----Ala and Asp-85----Glu: the blue form is inactive in proton translocation.

H. Khorana, T. Marti, H G Khorana, 1990, Proceedings of the National Academy of Sciences of the United States of America.

High-pressure liquid chromatography in polynucleotide synthesis.

H. Khorana, E. Brown, H. Fritz, 1978, Biochemistry.

Total synthesis of a tyrosine suppressor transfer RNA gene. XVII. Transcription, in vitro, of the synthetic gene and processing of the primary transcript to transfer RNA.

R. Contreras, H. Khorana, T. Sekiya, 1979, The Journal of biological chemistry.

Pyrophosphorylation of ribose 5-phosphate in the enzymatic synthesis of 5-phosphorylribose 1-pyrophosphate.

H. Khorana, A. Kornberg, J. F. Fernandes, 1958, The Journal of biological chemistry.

Vibrational spectroscopy of bacteriorhodopsin mutants. Evidence that Thr-46 and Thr-89 form part of a transient network of hydrogen bonds.

H. Khorana, T. Marti, K. Rothschild, 1992, The Journal of biological chemistry.

Total synthesis of a gene for bovine rhodopsin.

H. Khorana, D. Oprian, S. Karnik, 1986, Proceedings of the National Academy of Sciences of the United States of America.

387. Peptides. Part III. Selective degradation from the carboxyl end. The use of carbodi-imides

H. Khorana, 1952 .

Cyclic Phosphates. IV.1 Ribonucleoside-3',5' Cyclic Phosphates. A General Method of Synthesis and Some Properties

H. Khorana, G. Drummond, Michael Smith, 1961 .

Structure and function in rhodopsin: high level expression of a synthetic bovine opsin gene and its mutants in stable mammalian cell lines.

H. Khorana, R. Thurmond, P. Reeves, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Studies on Polynucleotides. XIV.1 Specific Synthesis of the C3"-C5" Interribonucleotide Linkage. Syntheses of Uridylyl-(3"5")-Uridine and Uridylyl-(3"5")-Adenosine2

H. Khorana, I. Goldberg, M. Smith, 1962 .

Studies on Polynucleotides. IX.1 Experiments on the Polymerization of Mononucleotides. Certain Protected Derivatives of Deoxycytidine-5' Phosphate and the Synthesis of Deoxycytidine Polynucleotides2

H. Khorana, A. Turner, J. P. Vizsolyi, 1961 .

Nucleoside Polyphosphates. XI.1 An Improved General Method for the Synthesis of Nucleotide Coenzymes. Syntheses of Uridine-5', Cytidine-5' and Guanosine-5' Diphosphate Derivatives

J. G. Moffatt, H. Khorana, S. Roseman, 1961 .

Nucleoside Polyphosphates. X.1 The Synthesis and Some Reactions of Nucleoside-5' Phosphoromorpholidates and Related Compounds. Improved Methods for the Preparation of Nucleoside-5' Polyphosphates1

J. G. Moffatt, H. Khorana, 1961 .

Nucleoside Polyphosphates. VIII.1 New and Improved Syntheses of Uridine Diphosphate Glucose and Flavin Adenine Dinucleotide Using Nucleoside-5' Phosphoramidates2

J. G. Moffatt, H. Khorana, 1958 .

A transposable element from Halobacterium halobium which inactivates the bacteriorhodopsin gene.

H. Khorana, S. DasSarma, M. Simsek, 1982, Proceedings of the National Academy of Sciences of the United States of America.

The role of the retinylidene Schiff base counterion in rhodopsin in determining wavelength absorbance and Schiff base pKa.

H. Khorana, T. Sakmar, R. Franke, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Studies on polynucleotides: XCVII. Opposing orientations and location of the suIII+ gene in the transducing coliphages φ80psuIII+ and φ80suIII+suIII−

H. Khorana, W. Szybalski, R. Miller, 1971 .

Specific amino acid substitutions in bacterioopsin: Replacement of a restriction fragment in the structural gene by synthetic DNA fragments containing altered codons.

H. Khorana, N. Hackett, K. Lo, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Carbodiimides. Part V.1 A Novel Synthesis of Adenosine Di- and Triphosphate and P1,P2-Diadenosine-5'-pyrophosphate

H. Khorana, 1954 .

Time-resolved site-directed spin-labeling studies of bacteriorhodopsin: loop-specific conformational changes in M.

H. Khorana, H. Steinhoff, W. Hubbell, 2000, Biochemistry.

Studies on polynucleotides. IV. Enzymic degradation; the stepwise action of venom phosphodiesterase on deoxyribo-oligonucleotides.

W. E. Razzell, H. Khorana, 1959, The Journal of biological chemistry.

The amino acid sequence of a glutamic acid-rich protein from bovine retina as deduced from the cDNA sequence.

H. Khorana, Y. Sugimoto, A. Ichikawa, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 1. General introduction.

M. Caruthers, H. Khorana, A. Kumar, 1976, The Journal of biological chemistry.

NMR spectroscopy of phosphorylated wild-type rhodopsin: mobility of the phosphorylated C-terminus of rhodopsin in the dark and upon light activation.

J. Klein-Seetharaman, H. Khorana, M. Sheves, 2004, Biochemistry.

Expression of the archaebacterial bacterio-opsin gene with and without signal sequences in Escherichia coli: the expressed proteins are located in the membrane but bind retinal poorly.

H. Khorana, S. Karnik, R. Molday, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Resonance Raman microprobe spectroscopy of rhodopsin mutants: effect of substitutions in the third transmembrane helix.

H. Khorana, R. Mathies, S. W. Lin, 1992, Biochemistry.

Synthesis of a gene for sensory rhodopsin I and its functional expression in Halobacterium halobium.

J. Spudich, H. Khorana, E. Spudich, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Expression of the bacterioopsin gene in Halobacterium halobium using a multicopy plasmid

H. Khorana, M. Krebs, M. P. Heyn, 1991, Proceedings of the National Academy of Sciences of the United States of America.

The Tyrosine tRNA Promoter

R. Contreras, H. Khorana, A. Landy, 1976 .

Dipolar assisted rotational resonance NMR of tryptophan and tyrosine in rhodopsin

H. Khorana, M. Sheves, Shobini Jayaraman, 2004, Journal of biomolecular NMR.

Magic angle spinning NMR of the protonated retinylidene Schiff base nitrogen in rhodopsin: expression of 15N-lysine- and 13C-glycine-labeled opsin in a stable cell line.

S. O. Smith, H. Khorana, P. Reeves, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Mapping light-dependent structural changes in the cytoplasmic loop connecting helices C and D in rhodopsin: a site-directed spin labeling study.

H. Khorana, W. Hubbell, K. Ridge, 1995, Biochemistry.

Structure and function in rhodopsin: the fate of opsin formed upon the decay of light-activated metarhodopsin II in vitro.

H. Khorana, T. Sakamoto, 1995, Proceedings of the National Academy of Sciences of the United States of America.

[94] Preparation of nucleotides and derivatives

H. Khorana, Michael Smith, 1963 .

The transmembrane domain of glycophorin A as studied by cross-linking using photoactivatable phospholipids.

H. Khorana, R. Radhakrishnan, R. Robson, 1982, Journal of Biological Chemistry.

Amino acid sequence of the membranous segment of rabbit liver cytochrome b5. Methodology for separation of hydrophobic peptides.

H. Khorana, G. Gerber, K. Nihei, 1980, The Journal of biological chemistry.

Signal sequence of human preproparathyroid hormone is inactive in yeast

M. Freeman, H. Khorana, A. Rich, 1987, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Thiols and the diazo group in photoaffinity labels.

H. Khorana, C. M. Gupta, Y. Takagaki, 1980, Biochemical and biophysical research communications.

Intermolecular crosslinking of fatty acyl chains in phospholipids: use of photoactivable carbene precursors.

H. Khorana, G. Gerber, R. Radhakrishnan, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Role of the intradiscal domain in rhodopsin assembly and function.

H. Khorana, R. Molday, T. Doi, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Glycerophospholipid synthesis: improved general method and new analogs containing photoactivable groups.

H. Khorana, R. Radhakrishnan, C. M. Gupta, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Delipidation of bacteriorhodopsin and reconstitution with exogenous phospholipid.

H. Khorana, H. Bayley, K. S. Huang, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Effects of tryptophan mutation on the deprotonation and reprotonation kinetics of the Schiff base during the photocycle of bacteriorhodopsin.

H. Khorana, M. El-Sayed, T. Marti, 1992, Biophysical journal.

Effects of individual genetic substitutions of arginine residues on the deprotonation and reprotonation kinetics of the Schiff base during the bacteriorhodopsin photocycle.

H. Khorana, M. El-Sayed, T. Marti, 1991, Biophysical journal.

Effect of genetic modification of tyrosine-185 on the proton pump and the blue-to-purple transition in bacteriorhodopsin.

H. Khorana, M. El-Sayed, T. Mogi, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Effects of amino acid substitutions in the F helix of bacteriorhodopsin. Low temperature ultraviolet/visible difference spectroscopy.

H. Khorana, P. Ahl, T. Mogi, 1988, The Journal of biological chemistry.

Studies on Polynucleotides. XX.1Amino Acid Acceptor Ribonucleic Acids (1). The Synthesis and Properties of 2″ (or 3″)-O-(DL-Phenylalanyl)-adenosine, 2″ (or 3″)-O-(DL-Phenylalanyl)-uridine and Related Compounds2

H. Khorana, D. Rammler, 1963 .

Studies on Polynucleotides. VIII.1Experiments on the Polymerization of Mononucleotides. Improved Preparation and Separation of Linear Thymidine Polynucleotides. Synthesis of Corresponding Members Terminated in Deoxycytidine Residues2

H. Khorana, J. P. Vizsolyi, 1961 .

Use of the lipophilic tert-butyldiphenylsilyl protecting group in synthesis and rapid separation of polynucleotides.

H. Khorana, H. Fritz, R. Jones, 1978, Biochemistry.

The nucleotide sequence adjoining the CCA end of an Escherichia coli tyrosine transfer ribonucleic acid gene.

H. Khorana, T. Sekiya, P. Loewen, 1974, The Journal of biological chemistry.

Studies on Polynucleotides CXVIII. A FURTHER STUDY OF RIBONUCLEOTIDE INCORPORATION INTO DEOXYRIBONUCLEIC ACID CHAINS BY DEOXYRIBONUCLEIC ACID POLYMERASE I OF ESCHERICHIA COLI

H. Khorana, P. Loewen, J. V. Sande, 1972 .

Studies on polynucleotides. LXVII. Initiation of protein synthesis in vitro as studied by using ribopolynucleotides with repeating nucleotide sequences as messengers.

H. Khorana, D. Söll, H. Ghosh, 1967, Journal of molecular biology.

Studies on polynucleotides. LVI. Further syntheses, in vitro of copolypeptides containing two amino acids in alternating sequence dependent upon DNA-like polymers containing two nucleotides in alternating sequence.

H. Khorana, S. Nishimura, D. S. Jones, 1966, Journal of molecular biology.

Structure and function in rhodopsin. Requirements of a specific structure for the intradiscal domain.

H. Khorana, A. Anukanth, 1994, The Journal of biological chemistry.

Studies on polynucleotides. LI. Syntheses of the 64 possible ribotrinucleotides derived from the four major ribomononucleotides.

H. Khorana, D. Söll, E. Ohtsuka, 1966, Journal of the American Chemical Society.

Studies on Polynucleotides. XXX.1 A Comparative Study of Reagents for the Synthesis of the C3′-C5′ Internucleotidic Linkage2

H. Khorana, T. Jacob, 1964 .

Studies on Polynucleotides. XVI.1 Specific Synthesis of the C3″-C5″ Interribonucleotidic Linkage. Examination of Routes Involving Protected Ribonucleosides and Ribonucleoside-3″ Phosphates. Syntheses of Uridylyl-(3″→5″)-adenosine, Uridylyl-(3″→5″)-cytidine, Adenylyl-(3″→5″)-adenosine and Related Com

H. Khorana, D. Rammler, 1962 .

Role of group-conserved residues in the helical core of β2-adrenergic receptor

H. Khorana, V. Hornak, M. Eilers, 2007, Proceedings of the National Academy of Sciences.

Consequences of amino acid insertions and/or deletions in transmembrane helix C of bacteriorhodopsin.

H. Khorana, M. P. Heyn, T. Marti, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Reversal of bacteriophage T4 induced polynucleotide kinase action.

H. Khorana, J. Van De Sande, K. Kleppe, 1973, Biochemistry.

Chemical synthesis of polynucleotides.

H. Khorana, K. Agarwal, A. Yamazaki, 1972, Angewandte Chemie.

THE TOTAL SYNTHESIS OF COENZYME A

J. G. Moffatt, H. Khorana, 1959 .

Structure of the lipopolysaccharide from an Escherichia coli heptose-less mutant. I. Chemical degradations and identification of products.

H. Khorana, J. Tang, M. R. Rosner, 1979, The Journal of biological chemistry.

A further study of misreading of codons induced by streptomycin and neomycin using ribopolynucleotides containing two nucleotides in alternating sequence as templates.

H. Khorana, D. S. Jones, J. Davies, 1966, Journal of molecular biology.

Identification of core amino acids stabilizing rhodopsin.

Judith Klein-Seetharaman, Ivet Bahar, H Gobind Khorana, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Rhodopsin structure, dynamics, and activation: a perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking.

H Gobind Khorana, H. Khorana, C. Altenbach, 2003, Advances in protein chemistry.

Expression and purification of rhodopsin and its mutants from stable mammalian cell lines: application to NMR studies.

S. O. Smith, J. Klein-Seetharaman, H. Khorana, 1999, Biochemical Society transactions.

Structure and function in rhodopsin: peptide sequences in the cytoplasmic loops of rhodopsin are intimately involved in interaction with rhodopsin kinase.

H. Khorana, R. Thurmond, P. Reeves, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Studies on Polynucleotides. LX.1 The Use of Preformed Dinucleotide Blocks in Stepwise Synthesis of Deoxyribopolynucleotides2

H. Khorana, H. Kossel, M. Moon, 1967 .

Studies on Polynucleotides. LII.1 The Use of 2,4,6-Triisopropylbenzenesulfonyl Chloride for the Synthesis of Internucleotide Bonds2

H. Khorana, R. Lohrmann, 1966 .

Rhodopsin kinase: expression in baculovirus-infected insect cells, and characterization of post-translational modifications.

H. Khorana, James Inglese, C. Bruel, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Structure and function in rhodopsin: expression of functional mammalian opsin in Saccharomyces cerevisiae.

H. Khorana, R. Mollaaghababa, C. Kaiser, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Nucleoside Polyphosphates. VII.1The Use of Phosphoramidic Acids in the Synthesis of Nucleoside-5' Pyrophosphates

H. Khorana, R. Chambers, 1958 .

Nucleoside Polyphosphates. VI.1 An Improved and General Method for the Synthesis of Ribo- and Deoxyribonucleoside 5'-Triphosphates

H. Khorana, Michael Smith, 1958 .

Studies on polynucleotides. 73. Synthesis in vitro of polypeptides containing repeating tetrapeptide sequences dependent upon DNA-like polymers containing repeating tetranucleotide sequences: direction of reading of messenger RNA.

H. Khorana, H. Kössel, A. R. Morgan, 1967, Journal of molecular biology.

Deoxyoligonucleotide synthesis using a new phosphate protecting group.

H. Khorana, M. Fridkin, K. Agarwal, 1973, Journal of the American Chemical Society.

Specificity of sRNA for recognition of codons as studied by the ribosomal binding technique.

H. Khorana, D. Söll, E. Ohtsuka, 1966, Journal of molecular biology.

Methods for mutagenesis of the bacterioopsin gene.

H. Khorana, N. Hackett, M. Gilles-Gonzalez, 1986, Methods in enzymology.

Studies on Polynucleotides. XXVIII.1The Specific Synthesis of C3″-C5″-Linked Ribooligonucleotides (4).2The Stepwise Synthesis of Uridylyl-(3″ → 5″)-adenylyl-(3″ → 5″)-uridylyl-(3″ → 5″)-uridine3

H. Khorana, Y. Lapidot, 1963 .

The membrane-embedded segment of cytochrome b5 as studied by cross-linking with photoactivatable phospholipids. II. The nontransferable form.

H. Khorana, K. Wirtz, R. Radhakrishnan, 1983, The Journal of biological chemistry.

The membrane-embedded segment of cytochrome b5 as studied by cross-linking with photoactivatable phospholipids.

H. Khorana, R. Radhakrishnan, C. M. Gupta, 1983, The Journal of biological chemistry.

Studies on Polynucleotides. XXV.1 The Stepwise Synthesis of Specific Deoxyribopolynucleotides (5).1 Further Studies on the Synthesis of Internucleotide Bond by the Carbodiimide Method. The Synthesis of Suitably Protected Dinucleotides as Intermediates in the Synthesis of Higher Oligonucleotides3

H. Khorana, H. Schaller, 1963 .

(purple membrane/proton pump/oligonucleotide purification/site-sp4

H. Khorana, N. Hackett, Simon S. Jones, 2016 .

Total synthesis and expression of a gene for the alpha-subunit of bovine rod outer segment guanine nucleotide-binding protein (transducin).

H. Khorana, T. Sakmar, 1988, Nucleic acids research.

Studies on Polynucleotides. V.1 Stepwise Synthesis of Oligonucleotides. Syntheses of Thymidylyl-(5' → 3')-thymidylyl-(5' → 3')-thymidine and Deoxycytidylyl-(5' → 3')-deoxyadenylyl-(5' → 3')-thymidine2

H. Khorana, P. Gilham, 1959 .

Nucleoside Polyphosphates. III.1 Syntheses of Pyrimidine Nucleoside-2'(3'),5'-diphosphates

H. Khorana, R. H. Hall, 1955 .

Studies on polynucleotides. CII. The use of aromatic isocyanates for selective blocking of the terminal 3'-hydroxyl group in protected deoxyribooligonucleotides.

H. Khorana, K. Agarwal, 1972, Journal of the American Chemical Society.

Studies on polynucleotides

H. G. Khorana, H. Khorana, E. Ohtsuka, 1965 .

Rapid separation of synthetic oligonucleotide mixtures on aromatic cellulose derivatives.

H. Khorana, M. Fridkin, K. Agarwal, 1974, Methods in enzymology.

Use of trityl- and -naphthylcarbamoylcellulose derivatives in oligonucleotide synthesis.

H. Khorana, M. Fridkin, K. Agarwal, 1973, Biochemistry.

Studies on polynucleotides. 98. A convenient and general method for the preparation of protected dideoxyribonucleotides containing 5'-phosphate end groups.

H. Khorana, K. Agarwal, A. Yamazaki, 1971, Journal of the American Chemical Society.

Studies on Polynucleotides. I. A New and General Method for the Chemical Synthesis of the C5″-C3″ Internucleotidic Linkage. Syntheses of Deoxyribo-dinucleotides1

H. G. Khorana, H. Khorana, P. T. Gilham, 1958 .

Total Synthesis of the Gene for an Alanine Transfer Ribonucleic Acid from Yeast

K. L. Agarwal, H. G. Khorana, V. Sgaramella, 1970, Nature.

Studies on Polynucleotides. VII.1Approaches to the Marking of End Groups in Polynucleotide Chains: The Methylation of Phosphomonoester Groups2

H. Khorana, 1959 .

Studies on Polynucleotides. XI.1 Chemical Polymerization of Mononucleotides. The Synthesis and Characterization of Deoxyadenosine Polynucleotides2

H. Khorana, R. Ralph, 1961 .

The Synthesis of 9-α-D-Ribofuranosyladenine

H. Khorana, R. Wright, G. Tener, 1958 .

Phosphorylated Sugars. V.1 Syntheses of Arabinofuranose and Arabinopyranose 1-Phosphates

H. Khorana, R. Wright, 1958 .

Studies on Polynucleotides. XXIX.1The Specific Synthesis of C3″-C5″-Linked Ribooligonucleotides(5).2Homologous Adenine Oligonucleotides3

H. Khorana, Y. Lapidot, 1963 .

Phosphorylated Sugars. VI.1 Syntheses of α-D-Ribofuranose 1,5-Diphosphate and α-D-Ribofuranose 1-Pyrophosphate 5-Phosphate

H. Khorana, G. Tener, 1958 .

Phosphorylated Sugars. III. Syntheses of α-D-Ribofuranose 1-Phosphate

H. Khorana, R. Wright, G. Tener, 1957 .

Phosphorylated Sugars. I. A Synthesis of β-D-Ribofuranose 1-Phosphate

H. Khorana, R. Wright, 1956 .

Studies on Polynucleotides. XVIII.1 Experiments on the Polymerization of Mononucleotides. The Synthesis and Characterization of Deoxyguanosine Oligonucleotides2

H. Khorana, R. Ralph, H. Schaller, 1963 .

Mapping of contact sites in complex formation between transducin and light-activated rhodopsin by covalent crosslinking: Use of a photoactivatable reagent

H. Khorana, K Cai, H G Khorana, 2001, Proceedings of the National Academy of Sciences of the United States of America.

STUDIES ON POLYNUCLEOTIDES. CXLIII. A RAPID AND CONVENIENT METHOD FOR THE SYNTHESIS OF DEOXYRIBOOLIGONUCLEOTIDES CARRYING 5′-PHOSPHATE END GROUPS USING A NEW PROTECTING GROUP

H. Khorana, H. Fritz, D. Kleid, 1976 .

Changes in interhelical hydrogen bonding upon rhodopsin activation.

Markus Eilers, H Gobind Khorana, H. Khorana, 2005, Journal of molecular biology.

Synthesis of phospholipids containing photoactivatable carbene precursors in the headgroups and their crosslinking with membrane proteins.

H. Khorana, R. Radhakrishnan, Y. Takagaki, 1985, Biochimica et biophysica acta.

Immunological probes for bacteriorhodopsin. Identification of three distinct antigenic sites on the cytoplasmic surface.

H. Khorana, K. Kimura, T. Mason, 1982, The Journal of biological chemistry.

Structure and function in rhodopsin: effects of disulfide cross-links in the cytoplasmic face of rhodopsin on transducin activation and phosphorylation by rhodopsin kinase.

J. Klein-Seetharaman, H. Khorana, W. Hubbell, 1999, Biochemistry.

Structure and function in rhodopsin: rhodopsin mutants with a neutral amino acid at E134 have a partially activated conformation in the dark state.

H. Khorana, R. Thurmond, C. Altenbach, 1997, Proceedings of the National Academy of Sciences of the United States of America.

A rapid and efficient procedure for the purification of mitochondrial β-hydroxybutyrate dehydrogenase

H. Khorana, B. Burnett, 1985 .

Refolding of an integral membrane protein. Denaturation, renaturation, and reconstitution of intact bacteriorhodopsin and two proteolytic fragments.

H. Khorana, H. Bayley, E. London, 1981, The Journal of biological chemistry.

Synthesis of modified fatty acids and glycerophospholipid analogs.

H. Khorana, R. Radhakrishnan, Y. Takagaki, 1981, Methods in enzymology.

Purification and properties of a pyrimidine deoxyriboside phosphorylase from Escherichia coli.

W. E. Razzell, H. Khorana, 1958, Biochimica et biophysica acta.

Cyclic Phosphates. III. Some General Observations on the Formation and Properties of Five-, Six- and Seven-membered Cyclic Phosphate Esters

J. G. Moffatt, H. Khorana, R. Wright, 1957 .

Studies on polynucleotides. LXXII. Deoxyribooligonucleotide synthesis on a polymer support.

H. Khorana, H. Hayatsu, 1967, Journal of the American Chemical Society.

Deoxyribooligonucleotide Synthesis on a Polymer Support1

H. Khorana, H. Hayatsu, 1966 .

Structure and thermal stability of monomeric bacteriorhodopsin in mixed pospholipid/detergent micelles

H. Khorana, L. Stern, C. Brouillette, 1989, Proteins.

Nucleoside Polyphosphates. XII.1 The Total Synthesis of Coenzyme A2

J. G. Moffatt, H. Khorana, 1961 .

452. The chemistry of the melanins. Part I. The synthesis of 5 : 6-dihydroxyindole and related compounds

H. Khorana, R. Beer, K. Clarke, 1948 .

The bacteriorhodopsin gene.

H. Khorana, M. Simsek, J. Mccoy, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Chemical studies of biological membranes

H. Khorana, 1980 .

CXII. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining of the chemically synthesized polydeoxynucleotides to form the DNA duplex representing nucleotide sequence 1 to 20.

H. Khorana, V. Sgaramella, 1972, Journal of molecular biology.

Missense suppression of the tryptophan synthetase A-protein mutant A78.

H. Khorana, N. Gupta, 1966, Proceedings of the National Academy of Sciences of the United States of America.

Structure and function in rhodopsin: Mass spectrometric identification of the abnormal intradiscal disulfide bond in misfolded retinitis pigmentosa mutants

J. Klein-Seetharaman, H. Khorana, J Klein-Seetharaman, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Fatty acids containing photoactivable carbene precursors. Synthesis and photochemical properties of 3,3-bis(1,1-difluorohexyl)diazirine and 3-(1,1-difluorooctyl)-3H-diazirine

H. Khorana, B. Erni, 1980 .

Identification of the lipid-binding site of phosphatidylcholine-transfer protein with phosphatidylcholine analogs containing photoactivable carbene precursors.

H. Khorana, K. Wirtz, R. Radhakrishnan, 1983, European journal of biochemistry.

Partial primary structure of bacteriorhodopsin: sequencing methods for membrane proteins.

H. Khorana, G. Gerber, W. Herlihy, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Photoactivatable carbene-generating phospholipids: physical properties and use in detection of phase separations in lipid mixtures.

H. Khorana, R. Radhakrishnan, C. M. Gupta, 1981, Biochemistry.

CARBODIIMIDES: PART III. (A) A NEW METHOD FOR THE PREPARATION OF MIXED ESTERS OF PHOSPHORIC ACID. (B) SOME OBSERVATIONS ON THE BASE-CATALYZED ADDITION OF ALCOHOLS TO CARBODIIMIDES

H. Khorana, 1954 .

Light‐induced currents in Xenopus oocytes expressing bovine rhodopsin.

H. Khorana, E. Nasi, B. Knox, 1993, The Journal of physiology.

Vibrational spectroscopy of bacteriorhodopsin mutants: evidence for the interaction of proline-186 with the retinylidene chromophore.

H. Khorana, T. Marti, T. Mogi, 1990, Biochemistry.

Vibrational spectroscopy of bacteriorhodopsin mutants: chromophore isomerization perturbs tryptophan-86.

H. Khorana, T. Marti, T. Mogi, 1989, Biochemistry.

Aspartic acid-96 is the internal proton donor in the reprotonation of the Schiff base of bacteriorhodopsin.

H. Khorana, M. Lindau, M. Holz, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Vibrational spectroscopy of bacteriorhodopsin mutants: light-driven proton transport involves protonation changes of aspartic acid residues 85, 96, and 212.

H. Khorana, T. Marti, T. Mogi, 1988, Biochemistry.

Surface charge of bacteriorhodopsin detected with covalently bound pH indicators at selected extracellular and cytoplasmic sites.

H. Khorana, P. Scherrer, M. P. Heyn, 1994, Biochemistry.

Substitution of amino acids Asp-85, Asp-212, and Arg-82 in bacteriorhodopsin affects the proton release phase of the pump and the pK of the Schiff base.

H. Khorana, M. Holz, M. P. Heyn, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin.

H. Khorana, T. Sakmar, R. Franke, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Substitution of membrane-embedded aspartic acids in bacteriorhodopsin causes specific changes in different steps of the photochemical cycle.

H. Khorana, M. Duñach, P. Ahl, 1989, Biochemistry.

Replacement of aspartic acid-96 by asparagine in bacteriorhodopsin slows both the decay of the M intermediate and the associated proton movement.

H. Khorana, M. Holz, V. Skulachev, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Aspartic acid substitutions affect proton translocation by bacteriorhodopsin.

H. Khorana, T. Marti, T. Mogi, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Denaturation and renaturation of bacteriorhodopsin in detergents and lipid-detergent mixtures.

H. Khorana, E. London, H G Khorana, 1982, The Journal of biological chemistry.

Structure-function studies on bacteriorhodopsin. V. Effects of amino acid substitutions in the putative helix F.

H. Khorana, N. Hackett, L. Stern, 1987, The Journal of biological chemistry.

Evidence for Long Range Allosteric Interactions between the Extracellular and Cytoplasmic Parts of Bacteriorhodopsin from the Mutant R82A and Its Second Site Revertant R82A/G231C*

H. Khorana, M. P. Heyn, R. Mollaaghababa, 2000, The Journal of Biological Chemistry.

Proton transport by a bacteriorhodopsin mutant, aspartic acid-85-->asparagine, initiated in the unprotonated Schiff base state.

H. Khorana, M. Krebs, M. P. Heyn, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Rapid long-range proton diffusion along the surface of the purple membrane and delayed proton transfer into the bulk.

H. Khorana, P. Scherrer, M. P. Heyn, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Rhodopsin, photoreceptor of the rod cell. An emerging pattern for structure and function.

H. Khorana, 1992, The Journal of biological chemistry.

Mapping of the amino acids in membrane-embedded helices that interact with the retinal chromophore in bovine rhodopsin.

H. Khorana, H G Khorana, T A Nakayama, 1991, The Journal of biological chemistry.

The site of attachment of retinal in bacteriorhodopsin. A resonance Raman study.

T. Earnest, H. Khorana, H. Bayley, 1982, The Journal of biological chemistry.

Orientation of retinal in bacteriorhodopsin as studied by cross-linking using a photosensitive analog of retinal.

H. Khorana, H. Bayley, R. Radhakrishnan, 1982, The Journal of biological chemistry.

Light-driven proton translocation by bacteriorhodopsin reconstituted with the phenyl analog of retinal.

H. Khorana, H. Bayley, R. Radhakrishnan, 1981, The Journal of biological chemistry.

Mapping of the amino acids in the cytoplasmic loop connecting helices C and D in rhodopsin. Chemical reactivity in the dark state following single cysteine replacements.

H. Khorana, K. Ridge, C. Zhang, 1995, Biochemistry.

Structure and function in rhodopsin. Separation and characterization of the correctly folded and misfolded opsins produced on expression of an opsin mutant gene containing only the native intradiscal cysteine codons.

H. Khorana, Z. Lu, K. Ridge, 1995, Biochemistry.

Replacement of aspartic residues 85, 96, 115, or 212 affects the quantum yield and kinetics of proton release and uptake by bacteriorhodopsin.

H. Khorana, T. Marti, T. Mogi, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Vibrational spectroscopy of bacteriorhodopsin mutants: I. Tyrosine‐185 protonates and deprotonantes during the photocycle

H. Khorana, N. Hackett, T. Mogi, 1988, Proteins.

Bacteriorhodopsin mutants containing single tyrosine to phenylalanine substitutions are all active in proton translocation.

H. Khorana, N. Hackett, T. Mogi, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Effect of introducing different carboxylate-containing side chains at position 85 on chromophore formation and proton transport in bacteriorhodopsin.

H. Khorana, M. P. Heyn, H. Otto, 1992, Journal of Biological Chemistry.

Aspartic acid 85 in bacteriorhodopsin functions both as proton acceptor and negative counterion to the Schiff base.

H. Khorana, S. Subramaniam, D. A. Greenhalgh, 1992, The Journal of biological chemistry.

The retinylidene Schiff base counterion in bacteriorhodopsin.

H. Khorana, M. P. Heyn, T. Marti, 1991, The Journal of biological chemistry.

Structure-function studies on bacteriorhodopsin. X. Individual substitutions of arginine residues by glutamine affect chromophore formation, photocycle, and proton translocation.

H. Khorana, L. Stern, 1989, The Journal of biological chemistry.

A bacteriorhodopsin analog reconstituted with a nonisomerizable 13-trans retinal derivative displays light insensitivity.

H. Khorana, M. P. Heyn, T. Marti, 1992, The Journal of biological chemistry.

Studies on polynucleotides. III. Enzymic degradation; substrate specificity and properties of snake venom phosphodiesterase.

W. E. Razzell, H. Khorana, W E RAZZELL, 1959, The Journal of biological chemistry.

Replacement of leucine-93 by alanine or threonine slows down the decay of the N and O intermediates in the photocycle of bacteriorhodopsin: implications for proton uptake and 13-cis-retinal----all-trans-retinal reisomerization.

H. Khorana, K. Rothschild, S. Subramaniam, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Structure and function in bacteriorhodopsin: the effect of the interhelical loops on the protein folding kinetics.

H. Khorana, P. Booth, S. Allen, 2001, Journal of molecular biology.

Intermediates in the folding of the membrane protein bacteriorhodopsin

P. S. Kim, H. Khorana, P. Booth, 1995, Nature Structural Biology.

A single amino acid substitution in rhodopsin (lysine 248----leucine) prevents activation of transducin.

H. Khorana, D. Oprian, T. Sakmar, 1988, The Journal of biological chemistry.

Structure and function in rhodopsin: packing of the helices in the transmembrane domain and folding to a tertiary structure in the intradiscal domain are coupled.

H. Khorana, P. Garriga, J. Hwa, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Structure and function in rhodopsin: destabilization of rhodopsin by the binding of an antibody at the N-terminal segment provides support for involvement of the latter in an intradiscal tertiary structure.

H. Khorana, P. Reeves, K. Cha, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Expression of a bovine rhodopsin gene in Xenopus oocytes: demonstration of light-dependent ionic currents.

H. Khorana, D. Thompson, E. Nasi, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Combined solid state and solution NMR studies of α,ɛ-15N labeled bovine rhodopsin

Harald Schwalbe, Judith Klein-Seetharaman, Christian Richter, 2007 .

Carbodiimides. VII.1Tetra-p-nitrophenyl Pyrophosphate, a New Phosphorylating Agent

J. G. Moffatt, H. Khorana, 1957 .

SPECIFIC SYNTHESIS OF THE C5'-C3' INTER-RIBONUCLEOTIDE LINKAGE: THE SYNTHESIS OF URIDYLYL-(5' → 3')-URIDINE1,2

H. Khorana, Michael Smith, 1959 .

Substitution of amino acids in helix F of bacteriorhodopsin: effects on the photochemical cycle.

H. Khorana, P. Ahl, T. Mogi, 1989, Biochemistry.

Reconstitution of delipidated bacteriorhodopsin with endogenous polar lipids.

H. Khorana, C. Lind, B. Höjeberg, 1981, The Journal of biological chemistry.

[10] Delipidation, renaturation, and reconstitution of bacteriorhodopsin

H. Khorana, H. Bayley, E. London, 1982 .

Formation of the meta II photointermediate is accompanied by conformational changes in the cytoplasmic surface of rhodopsin.

H. Khorana, W. Hubbell, H G Khorana, 1993, Biochemistry.

Rhodopsin mutants that bind but fail to activate transducin.

H. Khorana, T. Sakmar, K. Hofmann, 1990, Science.

Structure and Function in Rhodopsin

H. Khorana, D. Farrens, G. Khorana, 1995, The Journal of Biological Chemistry.

Acetyl phosphatidylethanolamine in the reconstitution of ion pumps.

H. Khorana, E. Racker, A. Knowles, 1975, The Journal of biological chemistry.

Detection of a water molecule in the active-site of bacteriorhodopsin: hydrogen bonding changes during the primary photoreaction.

H. Khorana, T. Marti, H G Khorana, 1994, Biochemistry.

Site-directed isotope labelling and FTIR spectroscopy of bacteriorhodopsin

H. Khorana, T. Marti, U. RajBhandary, 1994, Nature Structural Biology.

The use of tryptophan mutants in identifying the 296 nm transient absorbing species during the photocycle of bacteriorhodopsin

H. Khorana, M. El-Sayed, T. Marti, 1991, FEBS letters.

Conserved amino acids in F‐helix of bacteriorhodopsin form part of a retinal binding pocket

H. Khorana, T. Mogi, L. Stern, 1989, FEBS letters.

Intramolecular charge transfer in the bacteriorhodopsin mutants Asp85-->Asn and Asp212-->Asn: effects of pH and anions.

H. Khorana, M. Krebs, M. P. Heyn, 1995, Biophysical journal.

Anion binding to the Schiff base of the bacteriorhodopsin mutants Asp-85----Asn/Asp-212----Asn and Arg-82----Gln/Asp-85----Asn/Asp-212----Asn.

H. Khorana, M. P. Heyn, T. Marti, 1992, The Journal of biological chemistry.

Mechanism of light-dependent proton translocation by bacteriorhodopsin

H. Khorana, M. Krebs, 1993, Journal of bacteriology.

The reaction of hydroxylamine with bacteriorhodopsin studied with mutants that have altered photocycles: selective reactivity of different photointermediates.

H. Khorana, T. Marti, K. Rothschild, 1991, Proceedings of the National Academy of Sciences of the United States of America.

GTPase of bovine rod outer segments: the amino acid sequence of the alpha subunit as derived from the cDNA sequence.

H. Khorana, K. Yatsunami, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Designer short peptide surfactants stabilize G protein-coupled receptor bovine rhodopsin

H. Khorana, Shuguang Zhang, P. Reeves, 2006, Proceedings of the National Academy of Sciences.

Study on polynucleotideCV. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Chemical synthesis of an icosadeoxyribonucleotide corresponding to the nucleotide sequence 31 to 50

H. Khorana, H. Büchi, 1972 .

SYNTHESES OF DIDEOXYRIBONUCLEOTIDES

W. E. Razzell, H. G. Khorana, H. Khorana, 1957 .

The Selective Acetylation of Terminal Hydroxyl Groups in Deoxyribo-oligonucleotides

H. Khorana, A. Stuart, 1963 .

Phosphorylated Sugars. II. The Preparation of the Anomeric Methyl 5-O-Benzyl-D-ribofuranoside 2,3-Cyclic Carbonates and the Study of their Reactions with Hydrogen Bromide in Acetic Acid

H. Khorana, G. Tener, 1957 .

Carbodiimides. VI. The Reaction of Dicyclohexylcarbodiimide with Yeast Adenylic Acid. A New Method for the Preparation of Monoesters of Ribonucleoside 2'- and 3'-Phosphates

H. Khorana, C. Dekker, 1954 .

Cyclic Phosphates. II. Further Studies of Ribonucleoside 2':3'-Cyclic Phosphates1

H. Khorana, G. Tener, 1955 .

Studies on Polynucleotides. XII.1 Experiments on the Polymerization of Mononucleotides. A Comparison of Different Polymerizing Agents and a General Improvement in the Isolation of Synthetic Polynucleotides2

H. Khorana, R. Ralph, J. P. Vizsolyi, 1962 .

The Labelling of Phosphomonoester End Groups in Amino Acid Acceptor Ribonucleic Acids and its use in the Determination of Nucleotide Sequences

H. Khorana, R. Ralph, R. Young, 1962 .

Studies on Polynucleotides. XVII.1 On the Mechanism of Internucleotide Bond Synthesis by the Carbodiimide Method2

H. Khorana, G. Weimann, 1962 .

Studies on Polynucleotides. XIII.1Stepwise Synthesis of Deoxyribo-oligonucleotides. An Alternative General Approach and the Synthesis of Thymidine Di-, Tri- and Tetranucleotides Bearing 3"-Phosphomonoester End Groups2

H. Khorana, G. Weimann, 1962 .

Nucleoside Polyphosphates. IX.1 The Reversible Formation of Pyrophosphates from Monoesters of Phosphoric Acid by Reaction with Acetic Anhydride2

H. Khorana, J. P. Vizsolyi, 1959 .

Studies on Polynucleotides. II.1 The Synthesis and Characterization of Linear and Cyclic Thymidine Oligonucleotides2

H. Khorana, R. Markham, G. Tener, 1958 .

Studies on Polynucleotides. VI.1Experiments on the Chemical Polymerization of Mononucleotides. Oligonucleotides Derived from Thymidine-3' Phosphate2

H. Khorana, A. Turner, 1959 .

Studies on Polynucleotides. XXXI.1The Specific Synthesis of C3'-C5'-Linked Ribopolynucleotides (6).2A Further Study of the Synthesis of Uridine Polynucleotides3

H. Khorana, C. Coutsogeorgopoulos, 1964 .

CV. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Chemical synthesis of an icosadeoxyribonucleotide corresponding to the nucleotide sequence 31 to 50.

H. Khorana, H. Büchi, 1972, Journal of molecular biology.

STUDIES ON POLYNUCLEOTIDES. XXXVI. THE SPECIFIC SYNTHESIS OF C3'-C5'-LINKED RIBOOLIGONUCLEOTIDES. IX. THE SYNTHESIS OF RIBODINUCLEOTIDES BEARING 3'-PHOSPHOMONOESTER GROUPS.

H. Khorana, D. Soell, 1965, Journal of the American Chemical Society.

Studies on polynucleotides, lxviii the primary structure of yeast phenylalanine transfer RNA.

H. Khorana, U. RajBhandary, R. Faulkner, 1967, Proceedings of the National Academy of Sciences of the United States of America.

Nucleoside Polyphosphates. IV.1 A New Synthesis of Guanosine 5'-Phosphate

J. G. Moffatt, H. Khorana, R. Chambers, 1957 .

A SYNTHESIS OF α-D-RIBOFURANOSE-1-PHOSPHATE

H. Khorana, R. Wright, G. Tener, 1955 .

CIX. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of a dodecadeoxynucleotide and a decadeoxynucleotide corresponding to the nucleotide sequence 46 to 65.

H. Khorana, A. Kumar, K. Agarwal, 1972, Journal of Molecular Biology.

CX. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of three decadeoxynucleotides corresponding to the nucleotide sequence 51 to 70.

M. Caruthers, H. Khorana, J. Van De Sande, 1972, Journal of molecular biology.

CXI. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of a dodecadeoxynucleotide and a heptadeoxynucleotide corresponding to the nucleotide sequence 66 to 77.

M. Caruthers, H. Khorana, 1972, Journal of Molecular Biology.

Studies on Polynucleotides. LXVI.1 The Synthesis of Deoxyribopolynucleotides Containing Repeating Tetranucleotide Sequences (3). A Further Study of the Synthetic Approach Involving Condensation of Preformed Oligonucleotide Blocks2

H. Khorana, E. Ohtsuka, 1967 .

Studies on Polynucleotides. XXVI.1The Stepwise Synthesis of Specific Deoxyribopolynucleotides (6).2The Synthesis of Thymidylyl-(3″ → 5″)-deoxyadenylyl-(3″ → 5″)-thymidylyl-(3″ → 5″)-thymidylyl-(3″ → 5″)-thymidine and of Polynucleotides Containing Thymidine and Deoxyadenosine in Alternating Sequence3

H. Khorana, G. Weimann, H. Schaller, 1963 .

STUDIES ON POLYNUCLEOTIDES. 33. THE LABELING OF END GROUPS IN POLYNUCLEOTIDE CHAINS: THE SELECTIVE ACETYLATION OF TERMINAL HYDROXYL GROUPS IN DEOXYRIBOPOLYNUCLEOTIDES.

H. Khorana, A. Stuart, 1964, Journal of Biological Chemistry.

Studies on Polynucleotides. XXI.1 Amino Acid Acceptor Ribonucleic Acids (2). The Labeling of Terminal 5″-Phosphomonoester Groups and a Preliminary Investigation of Adjoining Nucleotide Sequences2

H. Khorana, R. Ralph, R. Young, 1963 .

Studies on polynucleotides. L. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: a new double-stranded DNA-like polymer containing repeating dinucleotide sequences.

H. Khorana, R. Wells, E. Ohtsuka, 1965, Journal of molecular biology.

STUDIES ON POLYNUCLEOTIDES. 23. ENZYMIC DEGRADATION. AN EXONUCLEASE FROM LACTOBACILLUS ACIDOPHILUS R26. B. STEPWISE DEGRADATION OF OLIGONUCLEOTIDES.

W. Fiers, H. Khorana, 1963, The Journal of biological chemistry.

Studies on polynucleotides. CXLIII. A rapid and convenient method for the synthesis of deoxyribooligonucleotides carrying 5'-phosphate end groups using a new protecting group.

H. Khorana, H. Fritz, D. Kleid, 1976, Journal of the American Chemical Society.

Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 5. Synthesis of the deoxyribopolynucleotide segments representing the nucleotide sequence 71-103.

M. Caruthers, H. Khorana, M. Fridkin, 1976, The Journal of biological chemistry.

CIII. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast

M. Caruthers, H. Khorana, N. Gupta, 1972 .

Studies of polynucleotides. XCII. The synthesis of a deoxyribododecanucleotide containing specific amino acid codons.

H. Khorana, A. Kumar, 1969, Journal of the American Chemical Society.

STUDIES ON POLYNUCLEOTIDES. XLVI. THE SYNTHESIS OF HEXANUCLEOTIDES CONTAINING THE REPEATING TRINUCLEOTIDE SEQUENCES DEOXYCYCTIDYLYL-(3'--5')-DEOXYADENYLYL-(3'--5')-DEOXYADENOSINE AND DEOXYGUANYLYL-(3'--5')-DEOXYADENYLYL-(3'--5')-DEOXYADENOSINE.

H. Khorana, S. Narang, T. Jacob, 1965, Journal of the American Chemical Society.

THE STEPWISE DEGRADATION OF THYMIDINE OLIGONUCLEOTIDES BY SNAKE VENOM AND SPLEEN PHOSPHODIESTERASES

W. E. Razzell, H. Khorana, 1958 .

Studies on polynucleotides. 53. Syntheses of trinucleotides containing adenylate and 2'-deoxyadenylate units and a study of their effect on the binding of lysyl soluble ribonucleic acid to ribosomes.

H. Khorana, S. Nishimura, M. Moon, 1966, Biochemistry.

STUDIES ON POLYNUCLEOTIDES. XXXVII. THE SYNTHESIS OF SPECIFIC DEOXYRIBOPOLYNUCLEOTIDES. FURTHER EXAMINATION OF THE APPROACH INVOLVING STEPWISE SYNTHESIS.

H. Khorana, T. Jacob, 1965, Journal of the American Chemical Society.

Studies on Polynucleotides. XIX.1 The Specific Synthesis of C3″-C5″ Inter-ribonucleotidic Linkage.2 A New Approach and its Use in the Synthesis of C3″-C5″-Linked Uridine Oligonucleotides3

H. Khorana, D. Rammler, Y. Lapidot, 1963 .

Nucleoside Polyphosphates. II.1 A Synthesis of Uridine-5'-di- and and -Triphosphate2a

H. Khorana, R. H. Hall, 1954 .

Studies on Polynucleotides. LXII.1 Deoxyribopolynucleotides Containing Repeating Trinucleotide Sequences (4).2 Preparation of Suitably Protected Deoxyribotrinucleotides3

H. Khorana, S. Narang, T. Jacob, 1967 .

Studies on Polynucleotides. LXV.1 The Synthesis of Deoxyribopolynucleotides Containing Repeating Tetranucleotide Sequences (2)2

H. Khorana, H. Kossel, H. Buchi, 1967 .

Studies on polynucleotides. 93. A further study of the synthesis of deoxyribopolynucleotides using preformed oligonucleotide blocks.

H. Khorana, J. Hachmann, 1969, Journal of the American Chemical Society.

Studies on Polynucleotides. XXVII.1 The Stepwise Synthesis of Specific Deoxyribopolynucleotides (7).1 The Synthesis of Polynucleotides Containing Deoxycytidine and Deoxyguanosine in Specific Sequences and of Homologous Deoxycytidine Polynucleotides Terminating in Thymidine3

H. Khorana, H. Schaller, 1963 .

Secondary Structure and Aggregation in Deoxyguanosine Oligonucleotides

H. Khorana, R. Ralph, W. Connors, 1962 .

The Stepwise Synthesis of Ribo-Oligonucleotides Containing C3″-C5″ Internucleotidic Linkages

H. Khorana, Y. Lapidot, 1963 .

STUDIES ON POLYNUCLEOTIDES. 43. THE SYNTHESIS OF DEOXRIBOPOLYNUCLEOTIDES CONTAINING REPEATING DINUCLEOTIDE SEQUENCES.

H. Khorana, E. Ohtsuka, M. Moon, 1965, Journal of the American Chemical Society.

Studies on polynucleotides. LXIX. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: DNA-like polymers containing repeating trinucleotide sequences.

H. Khorana, R. Wells, S. Narang, 1967, Journal of molecular biology.

Studies on polynucleotides. 48. The in vitro synthesis of a co-polypeptide containing two amino acids in alternating sequence dependent upon a DNA-like polymer containing two nucleotides in alternating sequence.

H. Khorana, S. Nishimura, D. S. Jones, 1965, Journal of molecular biology.

Studies on polynucleotides. 103. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast.

M. Caruthers, H. Khorana, N. Gupta, 1972, Journal of molecular biology.

Studies on polynucleotides. CXVII. Hybridization of polydeoxynucleotides with tyrosine transfer RNA sequences to the r-strand of phi80psu + 3 DNA.

M. Caruthers, H. Khorana, A. Kumar, 1972, Journal of molecular biology.

Studies on nucleic acids: Total synthesis of a biologically functional gene

H. Khorana, 1978 .

Physical characterization and simultaneous purification of bacteriophage T4 induced polynucleotide kinase, polynucleotide ligase, and deoxyribonucleic acid polymerase.

H. Khorana, J. Lillehaug, J. Van De Sande, 1973, Biochemistry.

On the heterogeneity of the deoxyribonucleic acid associated with crystalline yeast cytochrome b2.

H. Khorana, A. Kornberg, R. Kornberg, 1965, Biochimica et biophysica acta.

Structural studies on transmembrane proteins. 2. Spin labeling of bacteriorhodopsin mutants at unique cysteines.

H. Khorana, C. Altenbach, W. Hubbell, 1989, Biochemistry.

Phosphroylated Sugars. IV.1 The Synthesis of D-Xylose 3-Phosphate via 1,2-O-Isopropylidene-D-Xylofuranose-3,5-cyclic Phosphate

J. G. Moffatt, H. Khorana, 1957 .

465. Studies on phosphorylation. Part XI. The reaction between carbodi-imides and acid esters of phosphoric acid. A new method for the preparation of pyrophosphates

H. Khorana, A. R. Todd, 1953 .

Gene replacement in Halobacterium halobium and expression of bacteriorhodopsin mutants.

H. Khorana, M. Krebs, R. Mollaaghababa, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Bacterio-opsin mRNA in wild-type and bacterio-opsin-deficient Halobacterium halobium strains.

H. Khorana, S. DasSarma, U. L. Rajbhandary, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Polynucleotide ligase-catalyzed joining of deoxyribo-oligonucleotides on ribopolynucleotide templates and of ribo-oligonucleotides on deoxyribopolynucleotide templates.

H. Khorana, J. Van De Sande, K. Kleppe, 1970, Proceedings of the National Academy of Sciences of the United States of America.

Studies on polynucleotides. The linkage of deoxyribopolynucleotide templates to cellulose and its use in their replication.

H. Khorana, A. Panet, 1974, The Journal of biological chemistry.

Regeneration of the native bacteriorhodopsin structure from two chymotryptic fragments.

H. Khorana, E. London, M. Liao, 1983, The Journal of biological chemistry.

A Transposable Element from Halobacterium Halobium which Inactivates the Bacteriorhodopsin Gene

H. Khorana, S. DasSarma, M. Simsek, 1982 .

The synthesis and cloning of two tyrosine suppressor tRNA genes with altered promoter sequences.

H. Khorana, E. Brown, R. Dunn, 1981, The Journal of biological chemistry.

The structure of lipopolysaccharide from an Escherichia coli heptose-less mutant. III. Two fatty acyl amidases from Dictyostelium discoideum and their action on lipopolysaccharide derivatives.

H. Khorana, M. Rosner, R. Verret, 1979, The Journal of biological chemistry.

Hydrogen bonding interactions with the Schiff base of bacteriorhodopsin. Resonance Raman spectroscopy of the mutants D85N and D85A.

H. Khorana, T. Marti, K. Rothschild, 1993, The Journal of biological chemistry.

Regeneration of native bacteriorhodopsin structure from fragments.

H. Khorana, H G Khorana, K. S. Huang, 1984, The Journal of biological chemistry.

The site of attachment of retinal in bacteriorhodopsin. The epsilon-amino group in Lys-41 is not required for proton translocation.

H. Khorana, K. Biemann, C. M. Gupta, 1982, The Journal of biological chemistry.

Site of attachment of retinal in bacteriorhodopsin.

R Radhakrishnan, H. Khorana, H. Bayley, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Differential dynamics in the G protein-coupled receptor rhodopsin revealed by solution NMR.

J. Klein-Seetharaman, H. Schwalbe, H. Khorana, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Preparation of a circular bihelical deoxyribonucleic acid containing repeating dinucleotide sequences.

H. Khorana, V. Paetkau, 1971, Biochemistry.

Deoxyribonucleic acid synthesis in cell-free extracts. 3. Catalytic properties of deoxyribonucleic acid polymerase II.

H. Khorana, T. Kornberg, M. Gefter, 1972, The Journal of biological chemistry.

A collision gradient method to determine the immersion depth of nitroxides in lipid bilayers: application to spin-labeled mutants of bacteriorhodopsin.

H. Khorana, C. Altenbach, W. Hubbell, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Removal of the carboxyl-terminal peptide does not affect refolding or function of bacteriorhodopsin as a light-dependent proton pump.

H. Khorana, M. Liao, 1984, The Journal of biological chemistry.

SYNTHETIC DEOXYRIBO-OLIGONUCLEOTIDES AS TEMPLATES FOR THE DNA POLYMERASE OF ESCHERICHIA COLI: NEW DNA-LIKE L-POLYMERS CONTAINING REPEATING NUCLEOTIDE SEQUENCES.

H. Khorana, E. Ohtsuka, M. Moon, 1965, Proceedings of the National Academy of Sciences of the United States of America.

SYNTHETIC DEOXYRIBOPOLYNUCLEOTIDES AS TEMPLATES FOR RIBONUCLEIC ACID POLYMERASE: THE FORMATION AND CHARACTERIZATION OF A RIBOPOLYNUCLEOTIDE WITH A REPEATING TRINUCLEOTIDE SEQUENCE.

H. Khorana, S. Nishimura, T. Jacob, 1964, Proceedings of the National Academy of Sciences of the United States of America.

CARBODIIMIDES: PART IV. THE FISSION OF N,N′-DI-p-TOLYL-O-BENZYL AND-O-ALLYL PSEUDOUREA ETHERS IN THE PRESENCE OF ACIDS

H. Khorana, 1954 .

Studies on polynucleotides, LXXXIV. On the role of ribosomal subunits in protein synthesis.

H. Khorana, H. Ghosh, 1967, Proceedings of the National Academy of Sciences of the United States of America.

STUDIES ON POLYNUCLEOTIDES. XXII. ENZYMIC DEGRADATION. AN EXONUCLEASE FROM LACTOBACILLUS ACIDOPHILUS R26. A. PURIFICATION, PROPERTIES, AND SUBSTRATE SPECIFICITY.

W. Fiers, H. Khorana, 1963, The Journal of biological chemistry.

Structure and function in rhodopsin: A tetracycline-inducible system in stable mammalian cell lines for high-level expression of opsin mutants

Philip J. Reeves, H. Khorana, P. Reeves, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Structural features of the C-terminal domain of bovine rhodopsin: a site-directed spin-labeling study.

H. Khorana, C. Altenbach, W. Hubbell, 1999, Biochemistry.

Single-cysteine substitution mutants at amino acid positions 55-75, the sequence connecting the cytoplasmic ends of helices I and II in rhodopsin: reactivity of the sulfhydryl groups and their derivatives identifies a tertiary structure that changes upon light-activation.

J. Klein-Seetharaman, H. Khorana, C. Altenbach, 1999, Biochemistry.

Structural features and light-dependent changes in the sequence 59-75 connecting helices I and II in rhodopsin: a site-directed spin-labeling study.

J. Klein-Seetharaman, H. Khorana, C. Altenbach, 1999, Biochemistry.

Studies on Polynucleotides LXXVIII. YEAST PHENYLALANINE TRANSFER RIBONUCLEIC ACID: TERMINAL SEQUENCES

H. Khorana, U. RajBhandary, R. Hoskinson, 1968 .

Studies on polynucleotides. LXXIV. Direct translation in vitro of single-stranded DNA-like polymers with repeating nucleotide sequences in the presence of neomycin B.

H. Khorana, R. Wells, A. R. Morgan, 1967, Journal of molecular biology.

The structure of lipopolysaccharide from a heptose-less mutant of Escherichia coli K-12. II. The application of 31P NMR spectroscopy.

H. Khorana, A. Satterthwait, M. Rosner, 1979, The Journal of biological chemistry.

Mutagenesis Studies of Rhodopsin Phototransduction

H. Khorana, T. Sakmar, R. Franke, 1992 .

Rhodopsin kinase: expression in mammalian cells and a two-step purification.

H. Khorana, P. Reeves, E. Getmanova, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Studies on light transduction by bacteriorhodopsin and rhodopsin.

H. Khorana, R. Graham, M. Gilles-Gonzalez, 1988, Cold Spring Harbor symposia on quantitative biology.

Structure and function in rhodopsin: correct folding and misfolding in two point mutants in the intradiscal domain of rhodopsin identified in retinitis pigmentosa.

H. Khorana, P. Garriga, X. Liu, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Molecular Biology of Light Transduction by the Mammalian Photoreceptor, Rhodopsin

H. Khorana, H G Khorana, 2000, Journal of biomolecular structure & dynamics.

Structural origins of constitutive activation in rhodopsin: Role of the K296/E113 salt bridge.

H Gobind Khorana, H. Khorana, D. Oprian, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Studies on polynucleotides. CXVI. A further study of the T4 ligase-catalyzed joining of DNA at base-paired ends.

H. Khorana, H G Khorana, V Sogaramella, 1972, Journal of molecular biology.

Studies on polynucleotides, C. A novel joining reaction catalyzed by the T4-polynucleotide ligase.

H. Khorana, J. Van De Sande, V. Sgaramella, 1970, Proceedings of the National Academy of Sciences of the United States of America.

324. The chemistry of bacteria. Part I. The synthesis of hydroxyindoles

H. Khorana, R. Beer, K. Clarke, 1948 .

Rhodopsin kinase: two mAbs binding near the carboxyl terminus cause time-dependent inactivation.

H. Khorana, P. Reeves, L. Niu, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Interaction of cholesterol with photoactivable phospholipids in sonicated vesicles.

H. Khorana, G. Gerber, C. M. Gupta, 1981, Biochimica et biophysica acta.

Studies on polynucleotides. CXIX. Transcription of short double-stranded deoxyribonucleic acids of defined nucleotide sequences.

H. Khorana, R. Kleppe, 1972, Journal of Biological Chemistry.

Studies on polynucleotides. LXXXVII. The joining of short deoxyribopolynucleotides by DNA-joining enzymes.

H. Khorana, N. Gupta, E. Ohtsuka, 1968, Proceedings of the National Academy of Sciences of the United States of America.

Structure and function in rhodopsin: mapping light-dependent changes in distance between residue 316 in helix 8 and residues in the sequence 60-75, covering the cytoplasmic end of helices TM1 and TM2 and their connection loop CL1.

J. Klein-Seetharaman, H. Khorana, C. Altenbach, 2001, Biochemistry.

Mapping of contact sites in complex formation between light-activated rhodopsin and transducin by covalent crosslinking: Use of a chemically preactivated reagent

H. Khorana, K Cai, H G Khorana, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Studies on polynucleotides. CXX. On the transcription of a synthetic 29-unit long deoxyribopolynucleotide.

H. Khorana, J. Dahlberg, T. Terao, 1972, The Journal of biological chemistry.

Structure and Mechanism in G Protein-coupled Receptors

H. Khorana, P. Reeves, Jong-Myoung Kim, 2002 .

High-frequency spontaneous mutation in the bacterio-opsin gene in Halobacterium halobium is mediated by transposable elements.

H. Khorana, S. DasSarma, U. L. Rajbhandary, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Structure-function studies on bacteriorhodopsin. IV. Purification and renaturation of bacterio-opsin polypeptide expressed in Escherichia coli.

H. Khorana, L. Stern, B. Chao, 1987, The Journal of biological chemistry.

Hydrophobic amino acids in the retinal-binding pocket of bacteriorhodopsin.

S. Subramaniam, H. Khorana, D. Farrens, 1993, The Journal of biological chemistry.

IDENTIFICATION OF THE LIPID BINDING SITE OF THE PHOSPHATIDYLCHOLINE EXCHANGE PROTEIN WITH A PHOTOSENSITIVE NITRENE AND CARBENE PRECURSOR OF PHOSPHATIDYLCHOLINE

H. Khorana, K. Wirtz, R. Radhakrishnan, 1980, Annals of the New York Academy of Sciences.

Total synthesis of a tyrosine suppressor transfer RNA gene. XVI. Enzymatic joinings to form the total 207-base pair-long DNA.

R. Contreras, H. Khorana, E. Brown, 1979, The Journal of biological chemistry.

Total synthesis of a tyrosine suppressor transfer RNA gene. XIV. Chemical synthesis of oligonucleotide segments corresponding to the terminal regions.

H. Khorana, E. Brown, H. Fritz, 1979, Journal of Biological Chemistry.

Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 6. Synthesis of the deoxyribopolynucleotide segments corresponding to the nucleotide sequence 100-126.

M. Caruthers, H. Khorana, J. Van De Sande, 1976, Journal of Biological Chemistry.

Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 10. Enzymatic joining of chemically synthesized segments to form the DNA duplex corresponding to the nucleotide sequence 86-126.

M. Caruthers, H. Khorana, K. Kleppe, 1976, The Journal of biological chemistry.

Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 7. Enzymatic joining of the chemically synthesized segments to form a DNA duplex corresponding to the nucleotide sequence 1-26.

H. Khorana, T. Sekiya, T. Takeya, 1976, The Journal of biological chemistry.

Progress in the total synthesis of the gene for ala-tRNA.

M. Caruthers, H. Khorana, N. Gupta, 1968, Cold Spring Harbor symposia on quantitative biology.

The Synthesis of Deoxyribo-Polynucleotides Containing Specific Nucleotide Sequences

H. Khorana, G. Weimann, H. Schaller, 1963 .

136. Peptides. Part IV. Selective removal of the C-terminal residue as a thiohydantoin. The use of diphenyl phosphorisothiocyanatidate

H. Khorana, R. Stedman, G. Kenner, 1953 .

Sites of interaction in the complex between beta- and gamma-subunits of transducin.

H. Khorana, J. Bubis, 1990, The Journal of biological chemistry.

Vibrational spectroscopy of bacteriorhodopsin mutants. Evidence that ASP-96 deprotonates during the M----N transition.

H. Khorana, T. Marti, K. Rothschild, 1991, The Journal of biological chemistry.

Covalently bound pH-indicator dyes at selected extracellular or cytoplasmic sites in bacteriorhodopsin. 2. Rotational orientation of helices D and E and kinetic correlation between M formation and proton release in bacteriorhodopsin micelles.

H. Khorana, P. Scherrer, M. P. Heyn, 1994, Biochemistry.

Nucleotide sequence studies on yeast phenylalanine sRNA.

H. Khorana, U. RajBhandary, R. Faulkner, 1966, Cold Spring Harbor symposia on quantitative biology.

Structure and function in rhodopsin. Studies of the interaction between the rhodopsin cytoplasmic domain and transducin.

H. Khorana, R. Graham, T. Sakmar, 1992, The Journal of biological chemistry.

Magic angle spinning NMR of the protonated retinylidene Schiff base nitrogen in rhodopsin: Expression of 15 N-lysine- and 13 C-glycine-labeled opsin in a stable cell line (HEK293S cellsyG protein-coupled receptorysignal transductiony11-cis retinalyvisual pigment)

H. Khorana, P. Reeves, M. Eilers, 1999 .

Vibrational spectroscopy of bacteriorhodopsin mutants. Evidence for the interaction of aspartic acid 212 with tyrosine 185 and possible role in the proton pump mechanism.

H. Khorana, T. Marti, K. Rothschild, 1990, The Journal of biological chemistry.

A redirected proton pathway in the bacteriorhodopsin mutant Tyr-57-->Asp. Evidence for proton translocation without Schiff base deprotonation.

H. Khorana, Å. Nilsson, T. Marti, 1994, The Journal of biological chemistry.

Location of the Retinal Chromophore in the Activated State of Rhodopsin*

H. Khorana, V. Hornak, A. Hirshfeld, 2009, Journal of Biological Chemistry.

Structure and function in rhodopsin: kinetic studies of retinal binding to purified opsin mutants in defined phospholipid-detergent mixtures serve as probes of the retinal binding pocket.

H. Khorana, P. Reeves, H G Khorana, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Promoter-dependent transcription of tRNAITyr genes using DNA fragments produced by restriction enzymes.

R. Contreras, H. Khorana, A. Landy, 1975, Proceedings of the National Academy of Sciences of the United States of America.

Solution NMR spectroscopy of [α-15N]lysine-labeled rhodopsin: The single peak observed in both conventional and TROSY-type HSQC spectra is ascribed to Lys-339 in the carboxyl-terminal peptide sequence

J. Klein-Seetharaman, H. Schwalbe, H. Khorana, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Probing the dark state tertiary structure in the cytoplasmic domain of rhodopsin: proximities between amino acids deduced from spontaneous disulfide bond formation between Cys316 and engineered cysteines in cytoplasmic loop 1.

J. Klein-Seetharaman, H. Khorana, C. Altenbach, 2001, Biochemistry.

Probing the dark state tertiary structure in the cytoplasmic domain of rhodopsin: proximities between amino acids deduced from spontaneous disulfide bond formation between cysteine pairs engineered in cytoplasmic loops 1, 3, and 4.

J. Klein-Seetharaman, H. Khorana, C. Altenbach, 2001, Biochemistry.

Solution 19F nuclear Overhauser effects in structural studies of the cytoplasmic domain of mammalian rhodopsin

J. Klein-Seetharaman, H. Schwalbe, H. Khorana, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Structure and function in rhodopsin: further elucidation of the role of the intradiscal cysteines, Cys-110, -185, and -187, in rhodopsin folding and function.

J. Klein-Seetharaman, H. Khorana, P. Reeves, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Sites of intermolecular crosslinking of fatty acyl chains in phospholipids carrying a photoactivable carbene precursor.

H. Khorana, C. Costello, C. M. Gupta, 1979, Proceedings of the National Academy of Sciences of the United States of America.

CARBODIIMIDES: PART II. THE REACTION OF SULPHONIC ACIDS WITH CARBODIIMIDES. A NEW METHOD OF PREPARATION OF SULPHONIC ANHYDRIDES

H. Khorana, 1953 .

TOTAL SYNTHESIS OF A BACTERIAL GENE I: CHEMICAL SYNTHESIS OF OLIGONUCLEOTIDES AND USE OF HIGH-PRESSURE LIQUID CHROMATOGRAPHY

Roger A. Jones, H. Khorana, E. Brown, 1978 .

Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 12. Synthesis of a DNA duplex corresponding to a sequence of 23 nucleotide units adjoining the C-C-A end.

H. Khorana, D. Kleid, B. Ramamoorthy, 1976, Journal of Biological Chemistry.

Chemical synthesis and cloning of a tyrosine tRNA gene.

H. Khorana, E. Brown, M. Ryan, 1979, Methods in enzymology.

TOTAL SYNTHESIS OF A BACTERIAL GENE II: THE TOTAL DNA INCLUDING THE PROMOTER AND ITS TRANSCRIPTION

R. Contreras, H. Khorana, E. Brown, 1978 .

ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID, XVI. OLIGONUCLEOTIDES AS TEMPLATES AND THE MECHANISM OF THEIR REPLICATION.

H. Khorana, A. Kornberg, A KORNBERG, 1964, Proceedings of the National Academy of Sciences of the United States of America.

Covalently bound pH-indicator dyes at selected extracellular or cytoplasmic sites in bacteriorhodopsin. 1. Proton migration along the surface of bacteriorhodopsin micelles and its delayed transfer from surface to bulk.

H. Khorana, P. Scherrer, M. P. Heyn, 1994, Biochemistry.

Total synthesis of a tyrosine suppressor transfer RNA gene. XIII. Synthesis of deoxyribopolynucleotide segments corresponding to the nucleotide sequence -1 to -29 in the promoter region.

H. Khorana, E. Brown, M. Gait, 1979, The Journal of biological chemistry.

cDNA-derived amino acid sequence of the gamma subunit of GTPase from bovine rod outer segments.

H. Khorana, D. Oprian, K. Yatsunami, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Asp96 deprotonation and transmembrane alpha-helical structural changes in bacteriorhodopsin.

H. Khorana, T. Marti, K. Rothschild, 1993, Journal of Biological Chemistry.

Structure-function studies of bacteriorhodopsin XV. Effects of deletions in loops B-C and E-F on bacteriorhodopsin chromophore and structure.

H. Khorana, D. Engelman, M. Gilles‐Gonzalez, 1991, The Journal of biological chemistry.

Bacteriorhodopsin mutants containing single substitutions of serine or threonine residues are all active in proton translocation.

H. Khorana, M. P. Heyn, T. Marti, 1991, The Journal of biological chemistry.

Structure-function studies on bacteriorhodopsin. VIII. Substitutions of the membrane-embedded prolines 50, 91, and 186: the effects are determined by the substituting amino acids.

H. Khorana, T. Mogi, L. Stern, 1989, The Journal of biological chemistry.

Structure-function studies on bacteriorhodopsin. IX. Substitutions of tryptophan residues affect protein-retinal interactions in bacteriorhodopsin.

H. Khorana, T. Marti, T. Mogi, 1989, The Journal of biological chemistry.

Structure-Function Studies on Bacteriorhodopsin

Sadashiva S. Karnik, H. Khorana, S. Karnik, 1987 .

Magic angle spinning nuclear magnetic resonance of isotopically labeled rhodopsin.

H. Khorana, P. Reeves, M. Eilers, 2002, Methods in enzymology.

Site directed spin labeling studies of structure and dynamics in bacteriorhodopsin.

H. Khorana, H. Steinhoff, C. Altenbach, 1995, Biophysical chemistry.

Time-resolved detection of structural changes during the photocycle of spin-labeled bacteriorhodopsin.

H. Khorana, H. Steinhoff, K. Hideg, 1994, Science.

Incorporation of fatty acids containing photosensitive groups into phospholipids of Escherichia coli.

H. Khorana, G. R. Greenberg, P. Chakrabarti, 1976, Proceedings of the National Academy of Sciences of the United States of America.

CXV. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining to form the total DNA duplex.

M. Caruthers, H. Khorana, N. Gupta, 1972, Journal of molecular biology.

CXIV. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining of the chemically synthesized segments to form the DNA duplex corresponding to nucleotide sequence 46 to 77.

M. Caruthers, H. Khorana, J. Van De Sande, 1972, Journal of molecular biology.

Structure and function in rhodopsin: correct folding and misfolding in point mutants at and in proximity to the site of the retinitis pigmentosa mutation Leu-125-->Arg in the transmembrane helix C.

H. Khorana, P. Garriga, X. Liu, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Studies on polynucleotides, XLIX. Stimulation of the binding of aminoacyl-sRNA's to ribosomes by ribotrinucleotides and a survey of codon assignments for 20 amino acids.

H. Khorana, D. Söll, E. Ohtsuka, 1965, Proceedings of the National Academy of Sciences of the United States of America.

A Life in Science

H. Khorana, 2000, Science.

Structure and function in bacteriorhodopsin: the role of the interhelical loops in the folding and stability of bacteriorhodopsin.

H. Khorana, P. Booth, S. Allen, 2001, Journal of molecular biology.

Vibrational spectroscopy of bacteriorhodopsin mutants: light-driven proton transport involves protonation changes of aspartic acid residues 85, 96, and 212.

H. Khorana, T. Marti, T. Mogi, 1988, Biochemistry.

EFFECTS OF MUTAGENETIC SUBSTITUTION OF PROLINES ON THE RATE OF DEPROTONATION and REPROTONATION OF THE SCHIFF BASE DURING THE PHOTOCYCLE OF BACTERIORHODOPSIN

H. Khorana, M. El-Sayed, T. Marti, 1993, Photochemistry and photobiology.

FTIR difference spectroscopy of the bacteriorhodopsin mutant Tyr-185-->Phe: detection of a stable O-like species and characterization of its photocycle at low temperature.

H. Khorana, M. Krebs, K. Rothschild, 1993, Biochemistry.

Fourier transform Raman spectroscopy of the bacteriorhodopsin mutant Tyr-185-->Phe: formation of a stable O-like species during light adaptation and detection of its transient N-like photoproduct.

H. Khorana, M. Krebs, K. Rothschild, 1993, Biochemistry.

TIME‐RESOLVED FOURIER TRANSFORM INFRARED SPECTROSCOPY OF THE BACTERIORHODOPSIN MUTANT TYR‐185→E: ASP‐96 REPROTONATES DURING O FORMATION; ASP‐85 AND ASP‐212 DEPROTONATE DURING O DECAY

H. Khorana, M. Krebs, K. Rothschild, 1992, Photochemistry and photobiology.

Bacteriorhodopsin: partial sequence of mRNA provides amino acid sequence in the precursor region.

H. Khorana, E. Ohtsuka, M. Ikehara, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Total synthesis of a tyrosine suppressor tRNA gene. XV. Synthesis of the promoter region.

H. Khorana, E. Brown, T. Sekiya, 1979, The Journal of biological chemistry.

The synthesis and high‐level expression of a β2‐adrenergic receptor gene in a tetracycline‐inducible stable mammalian cell line

H. Khorana, P. Reeves, P. Chelikani, 2006, Protein science : a publication of the Protein Society.

Static and time-resolved absorption spectroscopy of the bacteriorhodopsin mutant Tyr-185-->Phe: evidence for an equilibrium between bR570 and an O-like species.

H. Khorana, M. Krebs, K. Rothschild, 1993, Biochemistry.

Structure and function in rhodopsin. 7. Point mutations associated with autosomal dominant retinitis pigmentosa.

S. Kaushal, H. Khorana, H. G. Khorana, 1994, Biochemistry.

sRNA specificity for codon recognition as studied by the ribosomal binding technique.

H. Khorana, D. Söll, D. S. Jones, 1966, Cold Spring Harbor symposia on quantitative biology.

The nucleotide sequence in the promoter region of the fene for an Escherichia coli tyrosine transfer ribonucleic acid.

H. Khorana, H. Ormondt, T. Sekiua, 1975, The Journal of biological chemistry.

Studies on polynucleotides. 118. A further study of ribonucleotide incorporation into deoxyribonucleic acid chains by deoxyribonucleic acid polymerase I of Escherichia coli.

H. Khorana, J. Van De Sande, P. Loewen, 1972, The Journal of biological chemistry.

Orientation of bacteriorhodopsin in Halobacterium halobium as studied by selective proteolysis.

H. Khorana, C. Gray, D. Wildenauer, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Structural studies on transmembrane proteins. 1. Model study using bacteriorhodopsin mutants containing single cysteine residues.

H. Khorana, S. Flitsch, 1989, Biochemistry.

Regeneration of native bacteriorhodopsin structure following acetylation of epsilon-amino groups of Lys-30, -40, and -41.

H. Khorana, D. Abercrombie, 1986, The Journal of biological chemistry.

Nucleotide Sequences at the Two Ends of the E. coli Tyrosine tRNA Genes and Studies on the Promoter

R. Contreras, H. Khorana, T. Sekiya, 1976 .

Combined solid state and solution NMR studies of alpha,epsilon-15N labeled bovine rhodopsin.

Harald Schwalbe, Judith Klein-Seetharaman, H Gobind Khorana, 2007, Journal of biomolecular NMR.

High-Level Expression, Single-Step Immunoaffinity Purification and Characterization of Human Tetraspanin Membrane Protein CD81

H. Khorana, Shuguang Zhang, P. Reeves, 2008, PloS one.

Specificity of sRNA for Recognition of Codons as Studied by the Ribosomal Binding Technique

H. Khorana, D. Söll, E. Ohtsuka, 1989 .

Structure and function in rhodopsin: topology of the C-terminal polypeptide chain in relation to the cytoplasmic loops.

H. Khorana, W. Hubbell, R. Langen, 1997, Proceedings of the National Academy of Sciences of the United States of America.

A new approach to the specific synthesis of the C3'-C5' inter-ribonucleotide linkage.

H. Khorana, D. Rammler, 1962, Biochemical and biophysical research communications.

STUDIES ON POLYNUCLEOTIDES.XLII. THE SYNTHESIS OF DEOXYRIBOPOLYNUCLEOTIDES CONTAINING REPEATING NUCLEOTIDE SEQUENCES. INTRODUCTION AND GENERAL CONSIDERATIONS.

H. Khorana, E. Ohtsuka, S. Narang, 1965, Journal of the American Chemical Society.

The preparation of lipid-depleted bacteriorhodopsin.

H. Khorana, D. Wildenauer, 1977, Biochimica et biophysica acta.

A new approach to the study of phospholipid-protein interactions in biological membranes. Synthesis of fatty acids and phospholipids containing photosensitive groups.

H. Khorana, P. Chakrabarti, G. Khorana, 1975, Biochemistry.

Structure-function studies on bacteriorhodopsin. III. Total synthesis of a gene for bacterio-opsin and its expression in Escherichia coli.

H. Khorana, S. Karnik, M. Nassal, 1987, Journal of Biological Chemistry.

Opsin stability and folding: the role of Cys185 and abnormal disulfide bond formation in the intradiscal domain.

H. Khorana, P. Booth, P. Reeves, 2007, Journal of molecular biology.

High-Level Expression , Single-Step Immunoaffinity Purification and Characterization of Human Tetraspanin Membrane Protein CD 81

H. Khorana, Shuguang Zhang, P. Reeves, 2008 .

Structure and function in rhodopsin. Cysteines 65 and 316 are in proximity in a rhodopsin mutant as indicated by disulfide formation and interactions between attached spin labels.

H. Khorana, C. Altenbach, D. Farrens, 1996, Biochemistry.

Studies on the light-transducing pigment bacteriorhodopsin.

H. Khorana, N. Hackett, D. S. Lee, 1983, Cold Spring Harbor symposia on quantitative biology.

113. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining of the chemically synthesized segments to form the DNA duplex corresponding to nucleotide sequence 17 to 50.

H. Khorana, N. Gupta, V. Sgaramella, 1972, Journal of molecular biology.