N. Brown

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Nucleotide sequence of bacteriophage phi X174 DNA.

F. Sanger, A. Coulson, B. Barrell, 1977, Nature.

Nucleotide sequence of bacteriophage φX174 DNA

F. Sanger, A. Coulson, B. Barrell, 1977, Nature.

Whole cell- and protein-based biosensors for the detection of bioavailable heavy metals in environmental samples

J. Lloyd, N. Brown, P. Corbisier, 1999 .

Bacterial metal-resistance proteins and their use in biosensors for the detection of bioavailable heavy metals.

J. Lloyd, N. Brown, E. Csöregi, 2000, Journal of inorganic biochemistry.

Molecular Microbiology

N. Brown, Christopher M Thomas, W. Busby, 1998, NATO ASI Series.

Investigation of sequence homology in a group of type-II restriction/modification isoschizomers.

N. Brown, R. Mullings, S. Bennett, 1988, Gene.

ZntR is a Zn(II)‐responsive MerR‐like transcriptional regulator of zntA in Escherichia coli

N. Brown, J. Hobman, B. Lawley, 1999, Molecular microbiology.

The MerR family of transcriptional regulators.

N. Brown, J. Hobman, S. Kidd, 2003, FEMS microbiology reviews.

The Escherichia coli Copper-responsivecopA Promoter Is Activated by Gold*

N. Brown, Jivko V. Stoyanov, 2003, The Journal of Biological Chemistry.

Biosensors for detection of mercury in contaminated soils.

Jaco Vangronsveld, Philippe Corbisier, Suzanne Leth, 2004, Environmental pollution.

The nucleotide sequence of bacteriophage phiX174.

T Friedmann, F. Sanger, A. Coulson, 1978, Journal of molecular biology.

Mercuric reductase structural genes from plasmid R100 and transposon Tn501: functional domains of the enzyme.

N. Brown, S. Silver, T. K. Misra, 1985, Gene.

MerF is a mercury transport protein: different structures but a common mechanism for mercuric ion transporters?

C. Leang, N. Brown, J. Hobman, 2000, FEBS letters.

Bacterial resistance to mercury — reductio ad absurdum?

N. Brown, 1985 .

Mercuric ion-resistance operons of plasmid R100 and transposon Tn501: the beginning of the operon including the regulatory region and the first two structural genes.

N. Brown, S. Silver, T. K. Misra, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Bacterial transport of and resistance to copper

N. Brown, S. Silver, B. T. Lee, 1994 .

Chromate reduction by Microbacterium liquefaciens immobilised in polyvinyl alcohol

N. Brown, L. Macaskie, P. Pattanapipitpaisal, 2004, Biotechnology Letters.

Chromate reduction and 16S rRNA identification of bacteria isolated from a Cr(VI)-contaminated site

N. Brown, L. Macaskie, P. Pattanapipitpaisal, 2001, Applied Microbiology and Biotechnology.

The nndeotide seqnence of tbe tnpA gene completes tbe sequence of the Pscudomonas transposon Tn50i

N. Brown, J. Winnie, D. Fritzinger, 2005 .

Induction of bacterial mercury- and copper-responsive promoters: Functional differences between inducible systems and implications for their use in gene-fusions for in vivo metal biosensors

N. Brown, J. Parkhill, D. Rouch, 1995, Journal of Industrial Microbiology.

Mercury Resistance Determinants Related to Tn21, Tn1696, and Tn5053 in Enterobacteria from the Preantibiotic Era

N. Brown, J. Hobman, S. Kidd, 2003, Antimicrobial Agents and Chemotherapy.

Cloning and Functional Analysis of thepbr Lead Resistance Determinant of Ralstonia metallidurans CH34

N. Brown, D. Lelie, B. Borremans, 2001, Journal of bacteriology.

Type II restriction endonucleases from Helicobacter pylori include an enzyme with a novel recognition sequence.

N. Brown, C. Penn, K. Jakeman, 1999, FEMS microbiology letters.

Accumulation and intracellular fate of tellurite in tellurite-resistant Escherichia coli: a model for the mechanism of resistance.

N. Brown, J. Hobman, A. Osborn, 1994, FEMS microbiology letters.

Generation of vector-insensitive dig-labeled probes from large cosmid library inserts using PCR.

N. Brown, J. Stephen, Julia M. Lodge, 1999, BioTechniques.

Horizontal spread of mer operons among gram-positive bacteria in natural environments.

N. Brown, J. Tiedje, J. Hobman, 1998, Microbiology.

Copper-resistant enteric bacteria from United Kingdom and Australian piggeries

N. Brown, J. Williams, D. Rouch, 1993, Applied and environmental microbiology.

Copper-Resistant Enteric Bacteria fromUnitedKingdomand

N. Brown, D. Rouch, A. G. Morgan, 1993 .

Sequence and Analysis of a Plasmid-Encoded Mercury Resistance Operon from Mycobacterium marinum Identifies MerH, a New Mercuric Ion Transporter

N. Brown, J. Parkhill, G. Besra, 2008, Journal of bacteriology.

A new approach to the remediation of heavy metal liquid wastes via off‐gases produced by Klebsiella pneumoniae M426

N. Brown, L. Macaskie, N. J. Creamer, 2006, Biotechnology and bioengineering.

Isolation and characterization of the M.EaeI modification methylase.

N. Brown, D. Jacobs, 1986, The Biochemical journal.

Evidence for direct interactions between the mercuric ion transporter (MerT) and mercuric reductase (MerA) from the Tn501mer operon

N. Brown, J. Hobman, M. Schué, 2008, BioMetals.

Mercury transport and resistance.

C. Leang, N. Brown, J. Hobman, 2001, Biochemical Society transactions.

Chemical and Genetic Studies of Copper Resistance in E. coli

N. Brown, J. Bryson, T. O’Halloran, 1993 .

bacterial mercury-resistance genes.

N. Brown, J. Hobman, 1997, Metal ions in biological systems.

Overexpression of MerT, the mercuric ion transport protein of transposon Tn501, and genetic selection of mercury hypersensitivity mutations

N. Brown, J. Hobman, 1996, Molecular and General Genetics MGG.

Three restriction endonucleases from Anabaena flos-aquae.

N. Brown, P. Whitehead, P. R. Whitehead, 1985, Journal of general microbiology.

The role of cysteine residues in the transport of mercuric ions by the Tn501 MerT and MerP mercury‐resistance proteins

N. Brown, J. Hobman, A. Morby, 1995, Molecular microbiology.

Molecular genetics and transport analysis of the copper‐resistance determinant (pco) from Escherichia coli plasmid pRJ1004

N. Brown, J. Camakaris, D. Rouch, 1995, Molecular microbiology.

Copper resistance determinants in bacteria.

N. Brown, D. Rouch, B. Lee, 1992, Plasmid.

Copper-inducible transcriptional regulation at two promoters in the Escherichia coli copper resistance determinant pco.

N. Brown, D. Rouch, 1997, Microbiology.

A new approach for the recovery of precious metals from solution and from leachates derived from electronic scrap

N. Brown, L. Macaskie, N L Brown, 2007, Biotechnology and bioengineering.

DNA of Myxococcus phage MX-1. Pyrimidine isostichs and the recognition of a minor pyrimidine.

J. H. Parish, N. Brown, D. Morris, 1976, Biochimica et biophysica acta.

Stimulation of microbial sulphate reduction in a constructed wetland: microbiological and geochemical analysis.

J. Lloyd, N. Brown, D. Parry, 2004, Water research.

Biological and genetic characterization of TnphoA mutants of Salmonella typhimurium TML in the context of gastroenteritis

N. Brown, G. Dougan, J. Stephen, 1995, Infection and immunity.

Detection of Alloiococcus otitis in mixed bacterial populations from middle-ear effusions of patients with otitis media

A. Fraise, N. Brown, B. Lawley, 1999, The Lancet.

The nucleotide sequence of bacteriophage φX174

Bart Barrell, C. A. Hutchison, Alan Coulson, 1978 .

The Pco proteins are involved in periplasmic copper handling in Escherichia coli.

N. Brown, C. Rensing, G. Grass, 2002, Biochemical and biophysical research communications.

The nucleotide sequence of the mercuric resistance operons of plasmid R100 and transposon Tn501: further evidence for mer genes which enhance the activity of the mercuric ion detoxification system

N. Brown, J. Winnie, S. Silver, 2004, Molecular and General Genetics MGG.

Bacterial resistances to mercury and copper

N. Brown, J. Parkhill, J. Camakaris, 1991, Journal of cellular biochemistry.

Role of the merT and merP gene products of transposon Tn501 in the induction and expression of resistance to mercuric ions.

N. Brown, P. Lund, Nigel L. Brown, 1987, Gene.

Transcriptional regulation of the mercury-resistance genes of transposon Tn501.

N. Brown, P. Lund, S. Ford, 1986, Journal of general microbiology.

Cysteine coordination of Pb(II) is involved in the PbrR-dependent activation of the lead-resistance promoter, PpbrA, from Cupriavidus metallidurans CH34

N. Brown, J. Hobman, Jon L Hobman, 2012, BMC Microbiology.

11 DNA Sequencing

N. Brown, P. Lund, 1988 .

13 DNA Sequencing

N. Brown, 1984 .

A general method for defining restriction enzyme cleavage and recognition sites.

N. Brown, M. Smith, 1980, Methods in enzymology.

A primed‐synthesis method for ribosubstitution of DNA at a single site

N. Brown, 1978, FEBS letters.

The sequence of a region of bacteriophage phiX174 DNA coding for parts of genes A and B.

N. Brown, M. Smith, 1977, Journal of molecular biology.

DNA sequence at the C termini of the overlapping genes A and B in bacteriophage φX174

F. Sanger, A. Coulson, B. Barrell, 1977, Nature.

DNA sequence of a region of the φX174 genome coding for a ribosome binding site

N. Brown, Michael B. Smith, 1977, Nature.

The Mapping and sequence determination of the single site in φX174am3 replicative form DNA cleaved by restriction endonuclease Pst I

N. Brown, Michaelj . Smith, 1976, FEBS letters.

EaeI: a restriction endonuclease from Enterobacter aerogenes

N. Brown, P. R. Whitehead, 1983, FEBS letters.

AhaIII: A restriction endonuclease with a recognition sequence containing only A:T basepairs

N. Brown, P. R. Whitehead, Philip R. Whitehead, 1982, FEBS letters.

HgiAI: a restriction endonuclease from Herpetosiphon giganteus HP1023.

N. Brown, Michael McClelland, P. R. Whitehead, 1980, Gene.

Transposition in prokaryotes: transposon Tn501.

N. Brown, L. Evans, 1991, Research in microbiology.

Climate factors influencing bacterial count in background air samples

Alan M. Jones, N. Brown, R. Harrison, 2005, International journal of biometeorology.

A Design for Life: Prokaryotic Metal-binding MerR Family Regulators

N. Brown, J. Hobman, J. Wilkie, 2005, Biometals.

Nucleotide sequence of a gene from the Pseudomonas transposon Tn501 encoding mercuric reductase.

N. Brown, R. Pridmore, D. Fritzinger, 1983, Biochemistry.

A complex family of class-II restriction endonucleases, DsaI-VI, in Dactylococcopsis salina.

F. Laue, N. Brown, M. Jarsch, 1991, Gene.

Molecular characterization of the gor gene encoding glutathione reductase from Pseudomonas aeruginosa: determinants of substrate specificity among pyridine nucleotide‐disulphide oxidoreductases

N. Brown, D. Rouch, A. Perr, 1991, Molecular microbiology.

Two-Component Systems in the Regulation of Heavy Metal Resistance

N. Brown, D. Nies, 1998 .

Metal Regulation of Gene Expression in Bacterial Systems

N. Brown, J. Hobman, B. Lawley, 1998 .

Bacterial Response to Copper in the Environment: Copper Resistance in Escherichia coli as a Model System

N. Brown, J. Camakaris, A. Bergemann, 1990 .

RNA polymerase-DNA interactions in Streptomyces. In vitro studies of a S. lividans plasmid promoter with S. coelicolor RNA polymerase.

N. Brown, M. Buttner, Nigel L. Brown, 1985, Journal of molecular biology.

CueR (YbbI) of Escherichia coli is a MerR family regulator controlling expression of the copper exporter CopA

N. Brown, J. Hobman, Jivko V. Stoyanov, 2001, Molecular microbiology.

Cleavage specificity of the restriction endonuclease isolated from Haemophilus gallinarum (Hga I).

N. Brown, M. Smith, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Iterative selection from a Salmonella typhimurium cosmid library can lead to the isolation of an atypically small plasmid.

N. Brown, J. Stephen, Julia M. Lodge, 1999, FEMS microbiology letters.

DNA of Myxococcus bacteriophage MX-1: Macromolecular properties and restriction fragments

J. H. Parish, N. Brown, D. Morris, 1976, Archives of Microbiology.

Nucleotide sequences at the ends of the mercury resistance transposon, Tn501.

N. Brown, M. Richmond, J. Grinsted, 1980, Nucleic acids research.

A simple and rapid method for screening bacteria for type II restriction endonucleases: enzymes in Aphanothece halophytica

N. Brown, P. R. Whitehead, 1985, Archives of Microbiology.

Mechanisms of mercury bioremediation.

N. Brown, L. Macaskie, A. Essa, 2001, Biochemical Society transactions.

Reduction of Cr(VI) and Bioaccumulation of Chromium by Gram Positive and Gram Negative Microorganisms not Previously Exposed to CR-Stress

N. Brown, J. Hobman, N. Ahmed, 2002, Environmental technology.

A Tn21 terminal sequence within Tn501: complementation of tnpA gene function and transposon evolution

N. Brown, J. Grinsted, 2004, Molecular and General Genetics MGG.

Extrachromosomal DNA in chloramphenicol resistant myxococcus strains.

J. H. Parish, N. Brown, 1976, Journal of general microbiology.

Microbial Mercury Reduction

N. Brown, J. Hobman, Jon Wilson, 2000 .

Type II restriction endonucleases from Bacillus sphaericus

N. Brown, R. Mullings, L. Evans, 1986 .

Restriction-modification genes from bacterial genera which produce PstI isoschizomers

N. Brown, R. Mullings, 1986 .

DNA sequences of and complementation by the tnpR genes of Tn21, Tn501 and Tn1721

N. Brown, R. Schmitt, J. Altenbuchner, 2004, Molecular and General Genetics MGG.

A New Method for Mercury Removal

N. Brown, L. Macaskie, Ashraf M M Essa, 2005, Biotechnology Letters.

Transcriptional Organization of the czcHeavy-Metal Homeostasis Determinant from Alcaligenes eutrophus

N. Brown, G. Grass, D. Nies, 1999, Journal of bacteriology.

Zinc dependence of zinT (yodA) mutants and binding of zinc, cadmium and mercury by ZinT.

N. Brown, J. Hobman, Christopher J. Kershaw, 2007, Biochemical and biophysical research communications.

Transcriptional activation of MerR family promoters in Cupriavidus metallidurans CH34

N. Brown, J. Hobman, Christopher J. Kershaw, 2009, Antonie van Leeuwenhoek.

Detection of heavy metal ions at femtomolar levels using protein-based biosensors.

B Mattiasson, J. Lloyd, N. Brown, 1998, Analytical chemistry.

The expression profile of Escherichia coli K-12 in response to minimal, optimal and excess copper concentrations.

Chrystala Constantinidou, C. Constantinidou, N. Brown, 2005, Microbiology.

Heavy metal resistance genes and proteins in bacteria and their application.

J. Lloyd, N. Brown, E. Csöregi, 1998, Biochemical Society transactions.

Bacterial metal-responsive elements and their use in biosensors for monitoring of heavy metals

J. Lloyd, N. Brown, P. Corbisier, 2002 .

Site-specific insertion and deletion mutants in the mer promoter-operator region of Tn501; the nineteen base-pair spacer is essential for normal induction of the promoter by MerR.

N. Brown, J. Parkhill, Julian Parkhill, 1990, Nucleic acids research.

Regulation of transcription in Escherichia coli from the mer and merR promoters in the transposon Tn501.

N. Brown, P. Lund, 1989, Journal of molecular biology.

Identification of the merR gene of R100 by using mer-lac gene and operon fusions

N. Brown, T. Foster, 1985, Journal of bacteriology.

Mercury Tolerance of Thermophilic Bacillus sp. and Ureibacillus sp

N. Brown, L. Macaskie, K. J. Glendinning, 2005, Biotechnology Letters.

Construction of hybrid Tn501/Tn21 transposases in vivo: identification of a region of transposase conferring specificity of recognition of the 38‐bp terminal inverted repeats.

N. Brown, L. Evans, 1987, EMBO Journal.

The nucleotide sequence of the tnpA gene completes the sequence of the Pseudomonas transposon Tn501.

N. Brown, J. Winnie, R. Pridmore, 1985, Nucleic acids research.

Protein-Based Capacitive Biosensors: a New Tool for Structure-Activity Relationship Studies

N. Brown, E. Csöregi, A. Mortari, 2008 .

Chapter 9 – Mercury Resistance in Bacteria

N. Brown, P. Lund, N. Bhriain, 1989 .

Construction and characterization of a mercury‐independent MerR activator (MerRAC): transcriptional activation in the absence of Hg(II) is accompanied by DNA distortion.

N. Brown, J. Parkhill, A. Ansari, 1993, The EMBO journal.

Two promoters from the Streptomyces plasmid pIJ101 and their expression in Escherichia coli.

N. Brown, M. Buttner, 1987, Gene.

Selection and characterization of mercury-independent activation mutants of the Tn501 transcriptional regulator, MerR.

N. Brown, J. Parkhill, J. Hobman, 1998, Microbiology.

The evolution of mercuric reductase, and a redox transfer model for mercuric ion detoxification in bacteria

N. Brown, D. Goddette, 1984 .

ZccR--a MerR-like regulator from Bordetella pertussis which responds to zinc, cadmium, and cobalt.

N. Brown, S. Kidd, 2003, Biochemical and biophysical research communications.

Restriction endonucleases from Herpetosiphon giganteus: an example of the evolution of DNA recognition specificity?

N. Brown, D. Jacobs, P. R. Whitehead, 1986, Nucleic acids research.

Phage and defective phage of strains of Myxococcus

J. H. Parish, N. Brown, N. Stow, 1976, Archives of Microbiology.