C. Fraser

Jaideep P. Sundaram, Christopher R. Hauser, Samuel V. Angiuoli, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Human, mouse, and rat genome large-scale rearrangements: stability versus speciation.

A. Delcher, R. Strausberg, Shaying Zhao, 2004, Genome research.

The Value of Complete Microbial Genome Sequencing (You Get What You Pay For)

S. Salzberg, C. Fraser, K. Nelson, 2002, Journal of bacteriology.

Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana

Eugen C. Buehler, B. Haas, S. Salzberg, 1999, Nature.

Genome Sequence of Theileria parva, a Bovine Pathogen That Transforms Lymphocytes

Jonathan E. Allen, Samuel V. Angiuoli, Bernard B. Suh, 2005, Science.

Mutations of two P/WS homologues in hereditary nonpolyposis colon cancer

R. Fleischmann, M. Adams, J. Venter, 1994, Nature.

An integrated 4249 marker FISH/RH map of the canine genome

G. Mahairas, E. Kirkness, C. Fraser, 2004, BMC Genomics.

Facilitating genome navigation: survey sequencing and dense radiation-hybrid gene mapping

K. Lindblad-Toh, E. Kirkness, T. Derrien, 2005, Nature Reviews Genetics.

Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440.

O. White, M. Pop, J. Peterson, 2002, Environmental microbiology.

Genome Stability of Lyme Disease Spirochetes: Comparative Genomics of Borrelia burgdorferi Plasmids

D. Radune, C. Fraser, J. Weidman, 2012, PloS one.

The Genome of the Basidiomycetous Yeast and Human Pathogen Cryptococcus neoformans

Jonathan E. Allen, Ronald W. Davis, Bernard B. Suh, 2005, Science.

Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

William H. Majoros, M. J. García, B. Haas, 2005, Nature.

Unsuspected diversity among marine aerobic anoxygenic phototrophs

E. Delong, C. Fraser, J. Eisen, 2002, Nature.

Insights on Evolution of Virulence and Resistance from the Complete Genome Analysis of an Early Methicillin-Resistant Staphylococcus aureus Strain and a Biofilm-Producing Methicillin-Resistant Staphylococcus epidermidis Strain

Samuel V. Angiuoli, Katherine H. Kang, C. Fraser, 2005, Journal of bacteriology.

Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii

Jonathan E. Allen, Samuel V. Angiuoli, Bernard B. Suh, 2002, Nature.

The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria

S. Salzberg, O. White, D. Radune, 2003, Nature.

The genome of the protist parasite Entamoeba histolytica

Bernard B. Suh, B. Barrell, M. Pop, 2005, Nature.

Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39.

S. Salzberg, O. White, J. Peterson, 2000, Nucleic acids research.

Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC): examining the role of niche-specific genes in the evolution of the Chlamydiaceae.

S. Salzberg, O. White, J. Peterson, 2003, Nucleic acids research.

Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana

Paul Shinn, Andre Marziali, William C. Nierman, 2000, Nature.

Cellular and Infection Microbiology Comparative Genomics and Stx Phage Characterization of Lee-negative Shiga Toxin-producing Escherichia Coli

C. Fraser, D. Rasko, J. Sahl, 2022 .

Refining the pathovar paradigm via phylogenomics of the attaching and effacing Escherichia coli

David A Rasko, Jason W Sahl, C. Fraser, 2013, Proceedings of the National Academy of Sciences.

Standardized Metadata for Human Pathogen/Vector Genomic Sequences

Brett E. Pickett, Richard H. Scheuermann, Lynn M. Schriml, 2014, PloS one.

Genomic Encyclopedia of Bacteria and Archaea: Sequencing a Myriad of Type Strains

Rick Stevens, Folker Meyer, Victor Markowitz, 2014, PLoS biology.

Phylogenetic discovery bias in Bacillus anthracis using single-nucleotide polymorphisms from whole-genome sequencing.

Paul Keim, Talima Pearson, Jacques Ravel, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Strain-Specific Single-Nucleotide Polymorphism Assays for the Bacillus anthracis Ames Strain

W. Ryan Easterday, Paul Keim, Talima Pearson, 2006, Journal of Clinical Microbiology.

The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1.

David A Rasko, Jacques Ravel, Ole Andreas Økstad, 2004, Nucleic acids research.

Continuous Particle Separation Through Deterministic Lateral Displacement

Michael T. Laub, Harley H. McAdams, Lucy Shapiro, 2004 .

The complete genome sequence of the Arabidopsis and tomato pathogen Pseudomonas syringae pv. tomato DC3000

Jia Liu, Alan Collmer, C Robin Buell, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Metaproteomics reveals persistent and phylum-redundant metabolic functional stability in adult human gut microbiomes of Crohn’s remission patients despite temporal variations in microbial taxa, genomes, and proteomes

Brandi L Cantarel, Alison R Erickson, Janet K Jansson, 2019, Microbiome.

The complete genome sequence of the Arabidopsis and tomato pathogen Pseudomonas syringae pv . tomato DC 3000

Ian T. Paulsen, C. Robin Buell, Alan Collmer, 2003 .

Mutation of a mutL homolog in hereditary colon cancer.

R. Fleischmann, M. Adams, J. Venter, 1994, Science.

All things great and small.

C. Fraser, 2004, Trends in microbiology.

The Genome Sequence of the Malaria Mosquito Anopheles gambiae

Jian Wang, Eugene W. Myers, Andrew G. Clark, 2002, Science.

Comparative Genome Sequencing for Discovery of Novel Polymorphisms in Bacillus anthracis

Mihai Pop, Steven L Salzberg, Paul Keim, 2002, Science.

In vitro mutagenesis and the search for structure-function relationships among G protein-coupled receptors.

C. Fraser, T. Savarese, C M Fraser, 1992, The Biochemical journal.

Transcriptional Attenuation Controls Macrolide Inducible Efflux and Resistance in Streptococcus pneumoniae and in Other Gram-Positive Bacteria Containing mef/mel(msr(D)) Elements

C. Fraser, H. Tettelin, S. Daugherty, 2015, PloS one.

Chapter 2 Adrenergic and muscarinic cholinergic receptors

C. Fraser, N. H. Lee, 1997 .

Genomic Loci of the Porphyromonas gingivalis Insertion Element IS1126

R. Fleischmann, C. Fraser, F. Dewhirst, 1999, Infection and Immunity.

Genetic Analysis and Attribution of Microbial Forensics Evidence

C. Fraser, R. Chakraborty, B. Budowle, 2005, Critical reviews in microbiology.

Non-classical receptive field mediates switch in a sensory neuron ’ s frequency tuning

S. Salzberg, O. White, D. Radune, 2022 .

Pulmonary Nontuberculous Mycobacterial Infection. A Multisystem, Multigenic Disease.

Andrew J. Oler, C. Fraser, H. Tettelin, 2015, American journal of respiratory and critical care medicine.

Genomics and future biological weapons: the need for preventive action by the biomedical community

Claire M. Fraser, C. Fraser, M. Dando, 2001, Nature Genetics.

The complexity of simplicity

Scott N Peterson, C. Fraser, S. Peterson, 2001, Genome Biology.

Comparison of the genome of the oral pathogen Treponema denticola with other spirochete genomes.

G. Weinstock, E. Sodergren, J. Malek, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Microbial genome sequencing

Jonathan A. Eisen, Steven L. Salzberg, Claire M. Fraser, 2000, Nature.

The Small‐Intestinal Sodium‐Glucose Cotransporter(s) a

J. Venter, C. Fraser, G. Semenza, 1985, Annals of the New York Academy of Sciences.

Molecular size of the canine and human brain D2 dopamine receptor as determined by radiation inactivation.

J. Venter, C. Fraser, P. Seeman, 1983, Molecular pharmacology.

A strong promoter element is located between alternative exons of a gene encoding the human gamma-aminobutyric acid-type A receptor beta 3 subunit (GABRB3).

E. Kirkness, C. Fraser, 1993, The Journal of biological chemistry.

Cloning and expression of adrenergic and muscarinic cholinergic receptor genes.

A. Kerlavage, J. Venter, C. Fraser, 1988, Advances in experimental medicine and biology.

Muscarinic cholinergic receptor structure: molecular biological support for subtypes

A. Kerlavage, J. Venter, C. Fraser, 1987 .

Autoantibodies to beta 2-adrenergic receptors: a possible cause of adrenergic hyporesponsiveness in allergic rhinitis and asthma

J. Venter, C. Fraser, L. Harrison, 1980, Science.

Monoclonal antibodies to beta-adrenergic receptors: use in purification and molecular characterization of beta receptors.

J. Venter, C. Fraser, 1980, Proceedings of the National Academy of Sciences of the United States of America.

The synthesis of beta-adrenergic receptors in cultured human lung cells: induction by glucocorticoids.

J. Venter, C. Fraser, C. Fraser, 1980, Biochemical and biophysical research communications.

Autonomic abnormalities and autoantibodies to beta-adrenergic receptors.

J. Venter, C. Fraser, Kaliner Ml, 1981, The New England journal of medicine.

Primordial origin and diversification of plasmids in Lyme disease agent bacteria

C. Fraser, E. Mongodin, S. Casjens, 2018, BMC Genomics.

Genomic insights into the Ixodes scapularis tick vector of Lyme disease

Gloria I. Giraldo-Calderón, Daniel R. Caffrey, Shelby L. Bidwell, 2016, Nature Communications.

Site-directed mutagenesis of N-linked glycosylation sites on the gamma-aminobutyric acid type A receptor alpha 1 subunit.

E. Kirkness, C. Fraser, A. Buller, 1994, Molecular pharmacology.

Molecular mechanisms of probiotic prevention of antibiotic-associated diarrhea.

C. Fraser, M. Marco, D. Merenstein, 2020, Current opinion in biotechnology.

Genomics at the genus scale.

C. Fraser, J. Ravel, 2005, Trends in microbiology.

Atopy, autonomic function and beta-adrenergic receptor autoantibodies.

J. Venter, C. Fraser, L. Harrison, 1982, Ciba Foundation symposium.

New Muscarinic Agonists with Special Emphasis on AF102B

C. Fraser, D. Gurwitz, A. Fisher, 1991 .

New signaling pathways govern the host response to C. albicans infection in various niches

Anup Mahurkar, C. Fraser, J. Ravel, 2015, Genome research.

Differential Response of the Cynomolgus Macaque Gut Microbiota to Shigella Infection

C. Fraser, D. Rasko, Zhenqiu Liu, 2013, PloS one.

Impact of Oral Typhoid Vaccination on the Human Gut Microbiota and Correlations with S. Typhi-Specific Immunological Responses

C. Fraser, D. Rasko, E. Drábek, 2013, PloS one.

Strains used in whole organism Plasmodium falciparum vaccine trials differ in genome structure, sequence, and immunogenic potential

James B. Munro, Zalak V. Shah, Joana C. Silva, 2020, Genome medicine.

Strains used in whole organism Plasmodium falciparum vaccine trials differ in genome structure, sequence, and immunogenic potential

James B. Munro, Zalak V. Shah, Joana C. Silva, 2019, Genome Medicine.

Transcriptional dysregulation in developing trigeminal sensory neurons in the LgDel mouse model of DiGeorge 22q11.2 deletion syndrome

C. Fraser, A. LaMantia, A. Horvath, 2020, Human molecular genetics.

Phylogenomic Identification of Regulatory Sequences in Bacteria: an Analysis of Statistical Power and an Application to Borrelia burgdorferi Sensu Lato

Che L. Martin, Pedro E. Pagan, C. Fraser, 2015, mBio.

Functional Dynamics of the Gut Microbiome in Elderly People during Probiotic Consumption

C. Fraser, J. Ravel, J. Crabtree, 2015, mBio.

Structural analysis of purified beta‐adrenergic receptors

A. Kerlavage, J. Venter, C. Fraser, 1987, Proteins.

Genetic mapping of the beta 1 GABA receptor gene to human chromosome 4, using a tetranucleotide repeat polymorphism.

E. Kirkness, S. O’Brien, C. Fraser, 1991, American journal of human genetics.

The genome sequence of the anaerobic, sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough

Rekha Seshadri, Kevin Tran, Gerrit Voordouw, 2004, Nature Biotechnology.

An Integrated Program in Microbial Genome Sequencing and Analysis

O. White, John Quackenbush, C. Fraser, 2005 .

Potential Influence of Staphylococcus aureus Clonal Complex 30 Genotype and Transcriptome on Hematogenous Infections

Jason R. Myers, C. Fraser, E. Mongodin, 2015, Open forum infectious diseases.

Monoclonal antibodies detect the conservation of muscarinic cholinergic receptor structure from Drosophila to human brain and detect possible structural homology with alpha 1-adrenergic receptors.

J. Venter, C. Fraser, B. Eddy, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Chapter 15 – Production of Monoclonal Antibodies to Integral Membrane Transport and Receptor Proteins and Their Use in Structural Elucidation

J. Venter, C. Fraser, B. Eddy, 1984 .

Changes in β1- and β2-adrenergic receptor mRNA levels in brown adipose tissue and heart of hypothyroid rats

C. Fraser, M. FitzGerald, J. Giacobino, 1991 .

Beta-3 adrenoceptor selectivity of the dioxolane dicarboxylate phenethanolamines.

C. Fraser, A. Strosberg, M. Dutia, 1994, The Journal of pharmacology and experimental therapeutics.

Genomics of Bacterial Pathogens

C. Fraser, K. Nelson, S. Gill, 2003 .

Complete genome sequence of Caulobacter crescentus

Ian T. Paulsen, William C. Nierman, J. Craig Venter, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Monoclonal A ntibodies to Integral Membrane Transport and Receptor Proteins Novel Reagents for Protein Purification

J. Venter, C. Fraser, G. Semenza, 1985 .

Biochemical Characterization of Brown Adipose Tissue β-Adrenergic Receptor

J. Venter, C. Fraser, P. Muzzin, 1988 .

Isolation of (a subunit of) the Na+/D‐glucose contransporter(s) of rabbit intestinal brush border membranes using monoclonal antibodies

C. Fraser, G. Semenza, J. Craig Venter, 1983, FEBS letters.

An adipose tissue-specific beta-adrenergic receptor. Molecular cloning and down-regulation in obesity.

J. Venter, C. Fraser, J. Gocayne, 1991, The Journal of biological chemistry.

Status of genome projects for nonpathogenic bacteria and archaea

C. Fraser, K. Nelson, I. Paulsen, 2000, Nature Biotechnology.

Autoantibodies to beta-adrenergic receptors and asthma.

J. Venter, C. Fraser, 1984, The Journal of allergy and clinical immunology.

Theileria parva candidate vaccine antigens recognized by immune bovine cytotoxic T lymphocytes.

N. J. Tonukari, C. Fraser, M. Gardner, 2006, Proceedings of the National Academy of Sciences of the United States of America.

The power in comparisons

C. Fraser, W. Nierman, 2004 .

New var reconstruction algorithm exposes high var sequence diversity in a single geographic location in Mali

Joana C. Silva, A. Delcher, O. Doumbo, 2017, Genome Medicine.

Non-pathogenic bacteria take center stage: a lesson in contrasts.

C. Fraser, G. Myers, 2004, Trends in microbiology.

Corrigendum: Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

William H. Majoros, M. J. García, B. Haas, 2006, Nature.

Defining the Phylogenomics of Shigella Species: a Pathway to Diagnostics

C. Fraser, M. Gilmour, D. Rasko, 2015, Journal of Clinical Microbiology.

Muscarinic acetylcholine receptor subtypes which selectively couple to phospholipase C: pharmacological and biochemical properties.

C. Fraser, M. Buck, 1990, Biochemical and biophysical research communications.

Continuous high density expression of human beta 2-adrenergic receptors in a mouse cell line previously lacking beta-receptors.

J. Venter, C. Fraser, F. Chung, 1987, The Journal of biological chemistry.

Alpha 1-adrenergic receptor structure.

J. Venter, C. Fraser, B. Eddy, 1984, Molecular pharmacology.

Monoclonal and anti-idiotypic antibodies as probes for receptor structure and function.

J. Venter, C. Fraser, J. Berzofsky, 1984, Federation proceedings.

Characterization of brain D2 dopamine receptors

J. Venter, C. Fraser, P. Seeman, 1985, Neurochemistry International.

The Structure and Evolution of Neurotransmitter Receptors (α- and β-Adrenergic, Dopaminergic and Muscarinic Cholinergic)

J. Venter, C. Fraser, 1984 .

Molecular size of the human platelet alpha 2-adrenergic receptor as determined by radiation inactivation.

J. Venter, C. Fraser, D. U'prichard, 1983, Biochemical and biophysical research communications.

Autoantibodies and monoclonal antibodies in the purification and molecular characterization of neurotransmitter receptors

J. Venter, C. Fraser, B. Eddy, 1983, Journal of cellular biochemistry.

Molecular properties of the slow inward calcium channel. Molecular weight determinations by radiation inactivation and covalent affinity labeling.

J. Venter, C. Fraser, D. Triggle, 1983, The Journal of biological chemistry.

Detergent solubilization of mammalian cardiac and hepatic β-adrenergic receptors☆

J. Venter, C. Fraser, G. Ghai, 1979 .

Genome Sequences of Rhinovirus B Isolates from Wisconsin Pediatric Respiratory Studies

C. Fraser, S. Liggett, Naomi A. Sengamalay, 2014, Genome Announcements.

Genome Sequences of Rhinovirus C Isolates from Wisconsin Pediatric Respiratory Studies

C. Fraser, S. Liggett, Naomi A. Sengamalay, 2014, Genome Announcements.

Discrepancies between the affinities of binding and action of the novel beta-adrenergic agonist BRL 37344 in rat brown adipose tissue.

J. Venter, C. Fraser, J. Giacobino, 1988, Biochemical and biophysical research communications.

Monoclonal Antibodies to β-Adrenergic Receptors and Receptor Structure

C. Fraser, 1984 .

Adrenergic and Muscarinic Receptor Structure

J. Venter, C. Fraser, 1983 .

Genome Sequences of Rhinovirus A Isolates from Wisconsin Pediatric Respiratory Studies

C. Fraser, S. Liggett, Naomi A. Sengamalay, 2014, Genome Announcements.

Purification and molecular characterization of neurotransmitter receptors.

J. Venter, C. Fraser, B. Eddy, 1983, Progress in clinical and biological research.

Regulation of beta-adrenergic receptor density in the control of adrenergic responsiveness.

J. Venter, C. Fraser, 1980, Progress in clinical and biological research.

Genomic Insights into the Emerging Human Pathogen Mycobacterium massiliense

David R. Riley, C. Fraser, H. Tettelin, 2012, Journal of bacteriology.

Beta-adrenergic receptors. Relationship of primary structure, receptor function, and regulation.

J. Venter, C. Fraser, 1990, The American review of respiratory disease.

The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications

Saurabh Raghuvanshi, Joachim Messing, Rod A Wing, 2005, BMC Biology.

Whole-Genome Sequences of Bacteremia Isolates of Bordetella holmesii

C. Fraser, H. Tettelin, Thomas A. Hooven, 2017, Genome Announcements.

Publisher Correction: Enterotypes in the landscape of gut microbial community composition

F. Bushman, G. Weinstock, P. Bork, 2018, Nature Microbiology.

Mutation Screening of the TNFRSF11A Gene Encoding Receptor Activator of NFkB (RANK) in Familial and Sporadic Paget's Disease of Bone and Osteosarcoma

M. Adams, A. Sparks, J. Venter, 2001, Calcified Tissue International.

The β-Adrenergic receptor, autoantibodies, and allergy: How are they related?

J. Venter, C. Fraser, D. Robinson, 1986 .

Whole-Genome Draft Sequences of 26 Enterohemorrhagic Escherichia coli O157:H7 Strains

C. Fraser, T. Cebula, J. Ravel, 2013, Genome Announcements.

The evolution of synaptic and cognitive capacity: Insights from the nervous system transcriptome of Aplysia

E. Kandel, T. Abrams, C. Fraser, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Detection of Borrelia garinii in the USA

C. Fraser, E. Mongodin, S. Casjens, 2022, bioRxiv.

Chromosome 2 sequence of the human malaria parasite Plasmodium falciparum.

E V Koonin, S. Salzberg, M. Adams, 1998, Science.

Molecular comparison of alpha 1- and alpha 2-adrenergic receptors suggests that these proteins are structurally related "isoreceptors".

J. Venter, C. Fraser, S. Shreeve, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Structural flexibility in the Burkholderia mallei genome.

O. White, D. Radune, C. Fraser, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Primary structure of rat cardiac beta-adrenergic and muscarinic cholinergic receptors obtained by automated DNA sequence analysis: further evidence for a multigene family.

A. Kerlavage, J. Venter, C. Fraser, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Agonist-mediated destabilization of m1 muscarinic acetylcholine receptor mRNA. Elements involved in mRNA stability are localized in the 3'-untranslated region.

C. Fraser, J. Earle-Hughes, N. H. Lee, 1994, The Journal of biological chemistry.

Major Structural Differences and Novel Potential Virulence Mechanisms from the Genomes of Multiple Campylobacter Species

David A Rasko, Jacques Ravel, Michael C Schatz, 2005, PLoS biology.

aerobic anoxygenic phototrophs

E. Delong, C. Fraser, J. Eisen, 2002 .

Probiotics: achieving a better regulatory fit.

C. Fraser, J. Ravel, D. Hoffmann, 2014, Food and drug law journal.

Genomic Insights into Methanotrophy: The Complete Genome Sequence of Methylococcus capsulatus (Bath)

Katherine H. Kang, S. Salzberg, C. Fraser, 2004, PLoS biology.

Roll with the flow: microbial masters of redox chemistry.

C. Fraser, B. Methé, 2004, Trends in microbiology.

A novel lipothrixvirus, SIFV, of the extremely thermophilic crenarchaeon Sulfolobus.

C. Fraser, T. Utterback, H. Klenk, 2000, Virology.

Functional Selection of Vaccine Candidate Peptides from Staphylococcus aureus Whole-Genome Expression Libraries In Vitro

C. Fraser, J. Söllner, S. Gill, 2003, Infection and Immunity.

Genome Sequence of the PCE-Dechlorinating Bacterium Dehalococcoides ethenogenes

Katherine H. Kang, A. Phillippy, C. Fraser, 2005, Science.

Complete Genome Sequence of the Oral Pathogenic Bacterium Porphyromonas gingivalis Strain W83

Ian T. Paulsen, Jonathan A. Eisen, Daniel H. Haft, 2003, Journal of bacteriology.

Transposition Pathovars in Genes Involved in Virulence 1448 A Reveals Divergence among pv . phaseolicola Pseudomonas syringae Whole-Genome Sequence Analysis of

O. White, T. Creasy, C. Fraser, 2005 .

Evolution of neurotransmitter receptor systems

A. Kerlavage, J. Venter, C. Fraser, 1988, Progress in Neurobiology.

An integrated genomic and transcriptomic survey of mucormycosis-causing fungi

C. Fraser, D. Rasko, J. Crabtree, 2016, Nature Communications.

Annotated draft genome sequences of three species of Cryptosporidium: Cryptosporidium meleagridis isolate UKMEL1, C. baileyi isolate TAMU-09Q1 and C. hominis isolates TU502_2012 and UKH1

Marcus C. Chibucos, Jessica C. Kissinger, Joshua Orvis, 2016, Pathogens and disease.

Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae

Ian T. Paulsen, Jonathan A. Eisen, Scott Peterson, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Analysis of complete genome sequence and major surface antigens of Neorickettsia helminthoeca, causative agent of salmon poisoning disease

C. Fraser, S. Daugherty, Naomi A. Sengamalay, 2017, Microbial biotechnology.

Discrete activation of transduction pathways associated with acetylcholine m1 receptor by several muscarinic ligands.

C. Fraser, D. Gurwitz, A. Fisher, 1994, European journal of pharmacology.

Pharmacological characterization of the M1 muscarinic receptors expressed in murine fibroblast B82 cells.

J. Venter, C. Fraser, H. Yamamura, 1989, The Journal of pharmacology and experimental therapeutics.

Dynamics of the infant gut microbiota in the first 18 months of life: the impact of maternal HIV infection and breastfeeding

C. Fraser, N. Ndembi, M. Charurat, 2022, Microbiome.

The Oral Bacterial Communities of Children with Well-Controlled HIV Infection and without HIV Infection

C. Fraser, E. Mongodin, Cheron Jones, 2015, PloS one.

Hervé Tettelin pneumoniae Streptococcus Complete Genome Sequence of a Virulent Isolate of

Samuel V. Angiuoli, S. Salzberg, O. White, 2013 .

Strategies for whole microbial genome sequencing and analysis

R. Fleischmann, C. Fraser, C M Fraser, 1997, Electrophoresis.

The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium

Ingeborg Holt, Fan Yang, Jonathan A Eisen, 2002, Proceedings of the National Academy of Sciences of the United States of America.

A model for high-throughput automated DNA sequencing and analysis core facilities

J. Craig Venter, Mark D. Adams, Jenny M. Kelley, 1994, Nature.

Mouse BAC ends quality assessment and sequence analyses.

J. Malek, C. Fraser, T. Feldblyum, 2001, Genome research.

Molecular Characterization of Autonomic and Neuropeptide Receptors

C. Fraser, N. H. Lee, 2017 .

Molecular properties and regulation of G-protein-coupled receptors.

A. Kerlavage, C. Fraser, N. H. Lee, 1994, Progress in nucleic acid research and molecular biology.

Cloning, sequence analysis and chromosome localization of a Drosophila muscarinic acetylcholine receptor

J. Venter, C. Fraser, J. Gocayne, 1989, FEBS letters.

Molecular biology of adrenergic and muscarinic cholinergic receptors. A perspective.

A. Kerlavage, J. Venter, C. Fraser, 1989, Biochemical pharmacology.

Cloning and sequence analysis of the human brain beta-adrenergic receptor. Evolutionary relationship to rodent and avian beta-receptors and porcine muscarinic receptors.

A. Kerlavage, J. Venter, C. Fraser, 1987, FEBS letters.

Targeted enrichment outperforms other enrichment techniques and enables more multi-species RNA-Seq analyses

C. Fraser, J. Foster, D. Rasko, 2018, Scientific Reports.

Defining a healthy human gut microbiome: current concepts, future directions, and clinical applications.

F. Bäckhed, C. Fraser, B. Finlay, 2012, Cell host & microbe.

Intratumor genetic heterogeneity in squamous cell carcinoma of the oral cavity

C. Fraser, L. Tallon, J. Papadimitriou, 2019, Head & neck.

Building comparative maps using 1.5x sequence coverage: human chromosome 1p and the canine genome.

E. Kirkness, T. Derrien, C. Fraser, 2003, Cold Spring Harbor Symposia on Quantitative Biology.

Genome sequences of 65 Helicobacter pylori strains isolated from asymptomatic individuals and patients with gastric cancer, peptic ulcer disease, or gastritis.

C. Fraser, W. F. Fricke, S. Daugherty, 2013, Pathogens and disease.

Laboratory Strains Clinical and Mycobacterium tuberculosis Whole-Genome Comparison of

S. Salzberg, R. Fleischmann, O. White, 2002 .

Comparative genomics and understanding of microbial biology.

R. Fleischmann, C. Fraser, J. Eisen, 2000, Emerging infectious diseases.

Genome data: what do we learn?

J A Eisen, R. Fleischmann, C. Fraser, 2000, Current opinion in structural biology.

A genomics-based approach to biodefence preparedness

C. Fraser, 2004, Nature Reviews Genetics.

Genetic exchange and plasmid transfers in Borrelia burgdorferi sensu stricto revealed by three-way genome comparisons and multilocus sequence typing.

Steven E Schutzer, John J Dunn, Oliver Attie, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Non-classical receptive field mediates switch in a sensory neuron ’ s frequency tuning

S. Salzberg, O. White, D. Radune, 2022 .

Sequence of Plasmodium falciparum chromosomes 2, 10, 11 and 14

Jonathan E. Allen, Samuel V. Angiuoli, Bernard B. Suh, 2002, Nature.

Aligner optimization increases accuracy and decreases compute times in multi-species sequence data

Ricky S. Adkins, Joana C. Silva, C. Fraser, 2017, Microbial genomics.

Alanine scanning mutagenesis of conserved arginine/lysine-arginine/lysine-X-X-arginine/lysine G protein-activating motifs on m1 muscarinic acetylcholine receptors.

C. Fraser, N. Geoghagen, N. H. Lee, 1996, Molecular pharmacology.

Enterotypes in the landscape of gut microbial community composition

Falk Hildebrand, Peer Bork, Rob Knight, 2017, Nature Microbiology.

Temporal Variability of Escherichia coli Diversity in the Gastrointestinal Tracts of Tanzanian Children with and without Exposure to Antibiotics

C. Fraser, D. Rasko, E. Silbergeld, 2018, mSphere.

Population dynamics of Escherichia coli in the gastrointestinal tracts of Tanzanian children

C. Fraser, D. Rasko, E. Silbergeld, 2018, bioRxiv.

Integrated Metagenomics/Metaproteomics Reveals Human Host-Microbiota Signatures of Crohn's Disease

Brandi L. Cantarel, Bernard Henrissat, Jeroen Raes, 2012, PloS one.

Role of Mobile DNA in the Evolution of Vancomycin-Resistant Enterococcus faecalis

T. D. Read, B. Dougherty, D. Radune, 2003, Science.

Establishing What Constitutes a Healthy Human Gut Microbiome: State of the Science, Regulatory Considerations, and Future Directions

Marie E. Latulippe, C. Huttenhower, C. Fraser, 2019, The Journal of nutrition.

Differences in the Platelet mRNA Landscape Portend Racial Disparities in Platelet Function and Suggest Novel Therapeutic Targets

C. Fraser, P. Friedman, A. Horvath, 2021, Clinical pharmacology and therapeutics.

Culture-Independent Evaluation of the Appendix and Rectum Microbiomes in Children with and without Appendicitis

C. Fraser, E. Mongodin, S. Zeichner, 2014, PloS one.

Radiation hybrid map, physical map, and low-pass genomic sequence of the canine prcd region on CFA9 and comparative mapping with the syntenic region on human chromosome 17.

J. Malek, C. Fraser, G. Acland, 2003, Genomics.

Toward a System of Microbial Forensics: from Sample Collection to Interpretation of Evidence

Bruce Budowle, Ranajit Chakraborty, Steven E Schutzer, 2005, Applied and Environmental Microbiology.

Enrichment of Gene-Coding Sequences in Maize by Genome Filtration

J Quackenbush, G. Pertea, J. Bennetzen, 2003, Science.

Molecular structure and evolution of adrenergic and cholinergic receptors

A. Kerlavage, J. Venter, C. Fraser, 1986, Proteins.

Genome-wide diversity and gene expression profiling of Babesia microti isolates identify polymorphic genes that mediate host-pathogen interactions

Olukemi O. Ifeonu, Joana C. Silva, Choukri Ben Mamoun, 2016, Scientific Reports.

Gut Microbiota in Multiple Sclerosis

A. Venkatesan, C. Fraser, J. Warrington, 2015, Journal of Investigative Medicine.

Anti-receptor antibodies in human disease.

J. Venter, C. Fraser, 1984, The Journal of allergy and clinical immunology.

Receptors on Airway Smooth Muscle

J. Venter, C. Fraser, J. Douglas, 1990 .

Attenuated Lassa Vaccine Candidate of an In Vivo and In Vitro Genetic Variation

C. Fraser, G. Myers, J. Carr, 2014 .

Genetic Variation In Vitro and In Vivo of an Attenuated Lassa Vaccine Candidate

C. Fraser, G. Myers, J. Carr, 2013, Journal of Virology.

Aerosol Mycobacterium tuberculosis Infection Causes Rapid Loss of Diversity in Gut Microbiota

Emiley Eloe-Fadrosh, William Bishai, Shashank Gupta, 2014, PloS one.

Comparative Analysis of Genome of Ehrlichia sp. HF, a Model Bacterium to Study Fatal Human Ehrlichiosis

C. Fraser, S. Daugherty, Naomi A. Sengamalay, 2021, BMC genomics.

Whole-Genome Analysis of Human Influenza A Virus Reveals Multiple Persistent Lineages and Reassortment among Recent H3N2 Viruses

Bryan T Grenfell, Yiming Bao, Steven L Salzberg, 2005, PLoS biology.

Cloning, localization, and permanent expression of a Drosophila octopamine receptor

J. Venter, C. Fraser, J. Gocayne, 1990, Neuron.

Erratum: The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus

C R Woese, G J Olsen, J Quackenbush, 1998, Nature.

Simultaneous Transcriptional Profiling of Bacteria and Their Host Cells

U. Farooq, T. Creasy, C. Fraser, 2013, PloS one.

Sequenced strains must be saved from extinction

C. Fraser, J. Eisen, E. Stackebrandt, 2001, Nature.

The Metagenomics and Metadesign of the Subways and Urban Biomes (MetaSUB) International Consortium inaugural meeting report

Emmanuel Dias-Neto, Joel Dudley, Mark Hernandez, 2016, Microbiome.

Characterization of Porphyromonas gingivalis Insertion Sequence-Like Element ISPg5

R. Fleischmann, C. Fraser, F. Dewhirst, 2000, Infection and Immunity.

Inter- and intra-specific pan-genomes of Borrelia burgdorferi sensu lato: genome stability and adaptive radiation

Steven E Schutzer, John J Dunn, Wei-Gang Qiu, 2013, BMC Genomics.

Nasal Microbiota and Infectious Complications After Elective Surgical Procedures

C. Fraser, E. Mongodin, K. Carroll, 2021, JAMA network open.

Whole genome comparisons of serotype 4b and 1/2a strains of the food-borne pathogen Listeria monocytogenes reveal new insights into the core genome components of this species.

David A Rasko, Jacques Ravel, Samuel V. Angiuoli, 2004, Nucleic acids research.

Gene synteny and evolution of genome architecture in trypanosomatids.

Samuel V. Angiuoli, S. Salzberg, M. Adams, 2004, Molecular and biochemical parasitology.

Lin, X. et al. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Nature 402, 761-768

William C. Nierman, Jonathan A. Eisen, J. Craig Venter, 1999 .

Single molecule sequencing and genome assembly of a clinical specimen of Loa loa, the causative agent of loiasis

C. Fraser, M. Chibucos, L. Tallon, 2014, BMC Genomics.

Draft Genome Sequence of Mortierella alpina Isolate CDC-B6842

C. Fraser, S. Daugherty, Joshua Orvis, 2014, Genome Announcements.

Genome sequencing of microbial species

C. Fraser, J. Ravel, 2005 .

Complete Genome Sequence of the Broad-Host-Range Vibriophage KVP40: Comparative Genomics of a T4-Related Bacteriophage

O. White, C. Fraser, T. Feldblyum, 2003, Journal of bacteriology.

Gene Transfer and Genome Plasticity in Thermotoga maritima, a Model Hyperthermophilic Species

Robert Huber, Karen E. Nelson, Emmanuel F. Mongodin, 2005, Journal of bacteriology.

Strain W 83 gingivalis Porphyromonas Pathogenic Bacterium Complete Genome Sequence of the Oral

R. Fleischmann, C. Fraser, H. Tettelin, 2003 .

Genome of Thermotoga maritima MSB8.

C. Fraser, K. Nelson, J. Eisen, 2001, Methods in enzymology.

Microbial genome sequencing 2000: new insights into physiology, evolution and expression analysis.

C. Fraser, J. Eisen, W. Nierman, 2000, Research in microbiology.

An Accidental Microbiologist

C. Fraser, 2000 .

Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species.

Rod A Wing, Wei Zhu, Carol Soderlund, 2005, Genome research.

Genome of Geobacter sulfurreducens: Metal Reduction in Subsurface Environments

J A Eisen, O. White, C. Fraser, 2003, Science.

Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.

W Ansorge, H Erfle, G Kauer, 2000, Nature.

Regulation of muscarinic receptor expression by changes in mRNA stability.

C. Fraser, N. H. Lee, 1995, Life Science.

Cross-talk between m1 muscarinic acetylcholine and beta 2-adrenergic receptors. cAMP and the third intracellular loop of m1 muscarinic receptors confer heterologous regulation.

C. Fraser, N. H. Lee, 1993, The Journal of biological chemistry.

Differential Gene Expression Profiles in G1 and S Phase Synchronized Jurkat T Cell Leukemia Cells: Investigation Using an Expressed Sequence Tag Analysis

M. Adams, E. Kirkness, G. Sutton, 1996 .

Comparative analysis of Chlamydia bacteriophages reveals variation localized to a putative receptor binding domain.

C. Fraser, T. Read, P. Bavoil, 2000, Microbial & comparative genomics.

Identification of in vivo expressed vaccine candidate antigens from Staphylococcus aureus

Johannes Söllner, Walter Schmidt, Duc Bui Minh, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Complete Genome Sequence of the Broad-Host-Range Vibriophage KVP 40 : Comparative Genomics of a T 4-Related Bacteriophage

O. White, C. Fraser, T. Feldblyum, 2003 .

Examination of the Enterotoxigenic Escherichia coli Population Structure during Human Infection

C. Fraser, D. Rasko, F. Qadri, 2015, mBio.

Gut microbiome and metabolome in a non-human primate model of chronic excessive alcohol drinking

C. Fraser, Xiaobai Li, Paule Valery Joseph, 2021, Translational Psychiatry.

Theileria parva genomics reveals an atypical apicomplexan genome.

C. Fraser, M. Gardner, V. Nene, 2000, International journal for parasitology.

Systemic and Terminal Ileum Mucosal Immunity Elicited by Oral Immunization With the Ty21a Typhoid Vaccine in Humans

C. Fraser, A. Fasano, M. Sztein, 2017, Cellular and molecular gastroenterology and hepatology.

Immune responses to Plasmodium vivax pre‐erythrocytic stage antigens in naturally exposed Duffy‐negative humans: a potential model for identification of liver‐stage antigens

Shelby L. Bidwell, C. Fraser, M. Gardner, 2005, European journal of immunology.

Site-directed mutagenesis of the rat m1 muscarinic acetylcholine receptor. Role of conserved cysteines in receptor function.

C. Fraser, T. Savarese, C. Wang, 1992, The Journal of biological chemistry.

BorreliaBase: a phylogeny-centered browser of Borrelia genomes

Saymon Akther, Lia Di, Benjamin J. Luft, 2014, BMC Bioinformatics.

How genomics has affected the concept of microbiology.

C. Fraser, N. Ward, 2005, Current opinion in microbiology.

Site-directed mutagenesis of alpha 2A-adrenergic receptors: identification of amino acids involved in ligand binding and receptor activation by agonists.

C. Fraser, C M Fraser, C D Wang, 1991, Molecular pharmacology.

Site-directed mutagenesis of m1 muscarinic acetylcholine receptors: conserved aspartic acids play important roles in receptor function.

J. Venter, C. Fraser, J. Gocayne, 1989, Molecular pharmacology.

Site-directed mutagenesis of human beta-adrenergic receptors: substitution of aspartic acid-130 by asparagine produces a receptor with high-affinity agonist binding that is uncoupled from adenylate cyclase.

J. Venter, C. Fraser, F. Chung, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Molecular biology of adrenergic receptors: model systems for the study of G-protein-mediated signal transduction.

C. Fraser, 1991, Blood & Vessel.

FADU: a Quantification Tool for Prokaryotic Transcriptomic Analyses

Ricky S. Adkins, C. Fraser, J. Mattick, 2021, mSystems.

The size of the mammalian lung beta 2-adrenergic receptor as determined by target size analysis and immunoaffinity chromatography.

J. Venter, C. Fraser, 1982, Biochemical and biophysical research communications.

Findings emerging from complete microbial genome sequences.

O. White, R. Clayton, C. Fraser, 1998, Current opinion in microbiology.

Compositional and Functional Differences in the Human Gut Microbiome Correlate with Clinical Outcome following Infection with Wild-Type Salmonella enterica Serovar Typhi

C. Fraser, L. Magder, Arthur Brady, 2018, mBio.

Salmonella Typhi Colonization Provokes Extensive Transcriptional Changes Aimed at Evading Host Mucosal Immune Defense During Early Infection of Human Intestinal Tissue

William A. Flavahan, C. Fraser, A. Fasano, 2018, EBioMedicine.

Targeted enrichment outperforms other enrichment techniques and enables more multi-species RNA-Seq analyses

C. Fraser, J. Foster, D. Rasko, 2018, bioRxiv.

Changes in the Gut Microbiota Following Bariatric Surgery Are Associated with Increased Alcohol Intake in a Female Rat Model.

C. Fraser, A. Hajnal, E. Orellana, 2021, Alcohol and alcoholism.

Cloning, sequence analysis, and permanent expression of a human alpha 2-adrenergic receptor in Chinese hamster ovary cells. Evidence for independent pathways of receptor coupling to adenylate cyclase attenuation and activation.

J. Venter, C. Fraser, W. McCombie, 1989, The Journal of biological chemistry.

A Distinct Gut Microbiota Exists Within Crohn's Disease-Related Perianal Fistulae.

C. Fraser, A. Bafford, Ryan D VanYperen, 2019, The Journal of surgical research.

Sequence analysis of the 5'-untranslated region of the human H1 histamine receptor-encoding gene.

C. Fraser, S. I. Max, B. A. Chowdhury, 1996, Gene.

Site-directed mutagenesis of beta-adrenergic receptors. Identification of conserved cysteine residues that independently affect ligand binding and receptor activation.

C. Fraser, 1989, The Journal of biological chemistry.

Transcriptional profiling of the hyperthermophilic methanarchaeon Methanococcus jannaschii in response to lethal heat and non-lethal cold shock.

Timothy A. Whitehead, C. Fraser, D. Clark, 2005, Environmental microbiology.

Plasmid diversity and phylogenetic consistency in the Lyme disease agent Borrelia burgdorferi

C. Fraser, E. Mongodin, S. Casjens, 2017, BMC Genomics.

Modeling Bacterial Evolution with Comparative-Genome-Based Marker Systems: Application to Mycobacterium tuberculosis Evolution and Pathogenesis

R. Fleischmann, C. Fraser, J. Eisen, 2003, Journal of bacteriology.

Monoclonal Antibodies to Integral Membrane Transport and Receptor Proteins

J. Venter, C. Fraser, G. Semenza, 1985 .

Champions of versatility.

C. Fraser, K. Nelson, 2004, Trends in microbiology.

Application of microbial genomic science to advanced therapeutics.

C. Fraser, R. Rappuoli, 2005, Annual review of medicine.

C. Fraser, H. Tettelin, S. Shallom, 2014, Emerging infectious diseases.

Genomic hybrid capture assay to detect Borrelia burgdorferi: an application to diagnose neuroborreliosis in horses

C. Fraser, E. Mongodin, S. Schutzer, 2022, Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.

Continuous monitoring of receptor-mediated changes in the metabolic rates of living cells.

J. W. Parce, J. Venter, C. Fraser, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Probiotics: Finding the Right Regulatory Balance

C. Fraser, J. Ravel, D. Hoffmann, 2013, Science.

Site-directed mutagenesis and continuous expression of human beta-adrenergic receptors. Identification of a conserved aspartate residue involved in agonist binding and receptor activation.

J. Venter, C. Fraser, C M Fraser, 1988, The Journal of biological chemistry.

A virus with big ambitions.

C. Fraser, E. Ghedin, 2005, Trends in microbiology.

Enterococcus faecalis conjugative plasmid pAM373: complete nucleotide sequence and genetic analyses of sex pheromone response

C. Fraser, E. D. De Boever, D. Clewell, 2000, Molecular microbiology.

Monoclonal antibodies detect the conservation of muscarinic cholinergic receptor structure from Drosophila to human brain and detect possible structural homology with a 1-adrenergic receptors ( anti-receptor monoclonal antibodies / isoelectric focusing / sodium dodecyl sulfate / polyacrylamide gel e

J. Venter, C. Fraser, B. Eddy, 2022 .