R. Sherrington

发表

Conservation of synteny between the genome of the pufferfish (Fugu rubripes) and the region on human chromosome 14 (14q24.3) associated with familial Alzheimer disease (AD3 locus)

S. Brenner, G. Elgar, M. Trower, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

D. Pollen, J. Haines, M. Pericak-Vance, 1995, Nature.

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice

Weiming Xia, Paul Fraser, J. Rommens, 1997, Nature Medicine.

Estimation of the genetic contribution of presenilin-1 and -2 mutations in a population-based study of presenile Alzheimer disease.

A Hofman, A. Hofman, J. Hardy, 1998, Human molecular genetics.

Structure of human glutathione S-transferase class Mu genes.

R. Sherrington, J. Taylor, S. Pemble, 1991, The Biochemical journal.

Misserise mutation of S182 gene in Italian families with early-onset Alzheimer's disease

R. Sherrington, E. Rogaev, S. Sorbi, 1995, The Lancet.

Evidence for inter-generational instability in the CAG repeat in the MJD1 gene and for conserved haplotypes at flanking markers amongst Japanese and Caucasian subjects with Machado-Joseph disease.

J. Weissenbach, K. Kidd, R. Sherrington, 1995, Human molecular genetics.

Missense mutation of S182 gene in Italian families with early-onset Alzheimer's disease.

R. Sherrington, E. Rogaev, S. Sorbi, 1995, Lancet.

Alzheimer’s Disease: Molecular Genetics

R. Sherrington, 2004 .

The Clinical phenotype of two missense mutations in the presenilin I gene in Japanese patients

G. Schellenberg, R. Sherrington, T. Bird, 1996, Annals of neurology.

Failure to detect missense mutations in the S182 gene in a series of late-onset Alzheimer's disease cases

D. Pollen, R. Sherrington, E. Rogaeva, 1995, Neuroscience Letters.

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

J. Rommens, R. Sherrington, E. Rogaev, 1995, Nature.

Presenilin Proteins Undergo Heterogeneous Endoproteolysis between Thr291and Ala299and Occur as Stable N- and C-Terminal Fragments in Normal and Alzheimer Brain Tissue

R. Sherrington, D. Selkoe, P. Fraser, 1997, Neurobiology of Disease.

Amyloid-β-protein isoforms in brain of subjects with PS1-linked, βAPP-linked and sporadic Alzheimer disease

D. Pollen, A. Roses, R. Sherrington, 1998 .

Presenilin Proteins and the Pathogenesis of Early-Onset Familial Alzheimer’s Disease: β-Amyloid Production and Parallels to Prion Diseases

J. Rommens, J. Roder, R. Sherrington, 1998 .

Analysis of the 5' sequence, genomic structure, and alternative splicing of the presenilin-1 gene (PSEN1) associated with early onset Alzheimer disease.

P E Fraser, J. Rommens, P. D. de Jong, 1997, Genomics.

Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant.

J. Rommens, Y. Agid, R. Sherrington, 1996, Human molecular genetics.

Intergenerational instability of the CAG repeat of the gene for Machado-Joseph disease (MJD1) is affected by the genotype of the normal chromosome: implications for the molecular mechanisms of the instability of the CAG repeat.

J. Weissenbach, Y. Agid, R. Sherrington, 1996, Human molecular genetics.

Amyloid-beta-protein isoforms in brain of subjects with PS1-linked, beta APP-linked and sporadic Alzheimer disease.

D. Pollen, A. Roses, R. Sherrington, 1998, Brain Research. Molecular Brain Research.