K. Wirtz

发表

The immunohistochemical localization of the non-specific lipid transfer protein (sterol carrier protein-2) in rat small intestine enterocytes.

F. Wouters, M. Markman, P. de Graaf, 1995, Biochimica et biophysica acta.

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

Geert J. P. L. Kops, K. Wirtz, R. Medema, 2002, Nature.

Lipids and membranes : past, present, and future : in honour of Laurens L.M. van Deenen

K. Wirtz, B. Roelofsen, L. Deenen, 1986 .

Oxidation of ER resident proteins upon oxidative stress: effects of altering cellular redox/antioxidant status and implications for protein maturation.

K. Wirtz, A. Verkleij, I. Braakman, 2003, Antioxidants & redox signaling.

Production of reactive oxygen species in mitochondria of HeLa cells under oxidative stress.

K. Wirtz, B. Chernyak, V. Skulachev, 2006, Biochimica et biophysica acta.

Phosphatidic acid is a specific activator of phosphatidylinositol-4-phosphate kinase.

K. Wirtz, W. Gispen, A. Moritz, 1992, The Journal of biological chemistry.

The phosphatidylcholine transfer protein from bovine liver discriminates between phosphatidylcholine isomers. A monolayer study.

K. Wirtz, R. Demel, D. van Loon, 1986, Biochimica et biophysica acta.

The non-specific lipid transfer protein (sterol carrier protein 2) acts as a peroxisomal fatty acyl-CoA binding protein.

F. Wouters, K. Wirtz, T. Jovin, 1998, Biochemical Society transactions.

Targeted Fluorescent Probes in Peroxisome Function

K. Wirtz, R. Wanders, T. Dansen, 2001, The Histochemical Journal.

Subcellular localisation and processing of non‐specific lipid transfer protein are not aberrant in Rhizomelic Chondrodysplasia Punctata fibroblasts

K. Wirtz, R. Wanders, R. Wanders, 1992, FEBS letters.

Sterol carrier protein X (SCPx) is a peroxisomal branched-chain beta-ketothiolase specifically reacting with 3-oxo-pristanoyl-CoA: a new, unique role for SCPx in branched-chain fatty acid metabolism in peroxisomes.

F. Wouters, K. Wirtz, S. Denis, 1997, Biochemical and biophysical research communications.

Mice without phosphatidylcholine transfer protein have no defects in the secretion of phosphatidylcholine into bile or into lung airspaces.

K. Wirtz, T. van der Poll, J. Wijnholds, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Phospholipid exchange between membranes. Purification of bovine brain proteins that preferentially catalyze the transfer of phosphatidylinositol.

K. Wirtz, G. M. Helmkamp, L. van Deenen, 1974, The Journal of biological chemistry.

Immunological comparison of phosphatidylinositol and phosphatidylcholine exchange proteins in bovine brain, liver and heart

K. Wirtz, G. M. Helmkamp, S. Nelemans, 1976 .

Activation of phosphatidylinositol transfer protein α and β isoforms from inclusion bodies

K. Wirtz, P. Gros, N. Dekker, 2001 .

Photolon, a chlorin e6 derivative, triggers ROS production and light-dependent cell death via necrosis.

K. Wirtz, V. Leaner, M. Parker, 2008, The international journal of biochemistry & cell biology.

Identification of proteins in activated human neutrophils susceptible to tyrosyl radical attack. A proteomic study using a tyrosylating fluorophore

K. Wirtz, A. Heck, E. Romijn, 2004, Proteomics.

Modulation of brain polyphosphoinositide metabolism by ACTH-sensitive protein phosphorylation

K. Wirtz, J. Jolles, W. Gispen, 1980, Nature.

Evidence for the existence of different pools of microsomal phosphatidylinositol by the use of phosphatidylinositol-exchange protein.

K. Wirtz, P. Brophy, P. Burbach, 1978, The Biochemical journal.

Transfer of phospholipids between membranes.

K. Wirtz, 1974, Biochimica et biophysica acta.

The LDL receptor as a model protein

K. Wirtz, A. Verkleij, I. Braakman, 2003 .

Determination of the acyl chain specificity of the bovine liver phosphatidylcholine transfer protein. Application of pyrene-labeled phosphatidylcholine species.

K. Wirtz, P. Somerharju, D. van Loon, 1987, Biochemistry.

Regulation of sterol carrier protein gene expression by the Forkhead transcription factor FOXO3a Published, JLR Papers in Press, October 16, 2003. DOI 10.1194/jlr.M300111-JLR200

K. Wirtz, S. Denis, R. Wanders, 2004, Journal of Lipid Research.

Transfer activity and acyl-chain specificity of phosphatidylcholine transfer protein by fluorescence assays.

K. Wirtz, P. Somerharju, J. Kasurinen, 1992, Methods in enzymology.

Affinity of phosphatidylcholine molecular species for the bovine phosphatidylcholine and phosphatidylinositol transfer proteins. Properties of the sn-1 and sn-2 acyl binding sites.

K. Wirtz, P. Somerharju, J. Kasurinen, 1990, Biochemistry.

Properties of the binding sites for the sn-1 and sn-2 acyl chains on the phosphatidylinositol transfer protein from bovine brain.

K. Wirtz, P. Somerharju, T. Gadella, 1988, Biochemistry.

The Protein Kinase C-dependent Phosphorylation of Serine 166 Is Controlled by the Phospholipid Species Bound to the Phosphatidylinositol Transfer Protein α*

K. Wirtz, J. Westerman, C. van Tiel, 2000, The Journal of Biological Chemistry.

The phosphatidylinositol transfer protein in 3T3 mouse fibroblast cells is associated with the Golgi system

K. Wirtz, G. Snoek, I. D. de Wit, 1992, Journal of cellular biochemistry.

The lipid binding site of the phosphatidylcholine transfer protein from bovine liver.

K. Wirtz, R. Demel, D. van Loon, 1985, Chemistry and physics of lipids.

A role for phosphatidylinositol transfer protein in secretory vesicle formation

K. Wirtz, W. Huttner, V. Bankaitis, 1995, Nature.

Production of reactive oxygen species in mitochondria of HeLa cells under oxidative stress. B.V.Chernyak, D.S.Izyumov, K.G.Lyamzaev, A.A.Pashkovskaya, O.Y.Pletjushkina, Y.N.Antonenko, D.V.Sakharov

K. Wirtz, B. Chernyak, V. Skulachev, 2006 .

Uptake and phosphorylation of phosphatidylinositol by rat liver nuclei. Role of phosphatidylinositol transfer protein.

K. Wirtz, M. Previati, S. Capitani, 1990, Biochimica et Biophysica Acta.

The protein-mediated net transfer of phosphatidylinositol in model systems.

K. Wirtz, R. Demel, L. M. Deenen, 1977, Biochimica et biophysica acta.

The Peroxisome in Oxidative Stress

K. Wirtz, T. Dansen, 2001, IUBMB life.

The synthesis and esterification of cholesterol by hepatocytes and H35 hepatoma cells are independent of the level of nonspecific lipid transfer protein.

K. Wirtz, G. P. V. van Heusden, M. Geelen, 1985, Biochimica et biophysica acta.

Hydroxymethylglutaryl CoA reductase and the modulation of microsomal cholesterol content by the nonspecific lipid transfer protein.

K. Wirtz, G. P. V. van Heusden, 1984, Journal of lipid research.

Increased cholesterol synthesis in Chinese hamster ovary cells deficient in peroxisomes.

K. Wirtz, R. Thieringer, C. Raetz, 1992, Biochimica et biophysica acta.

Peptide-based targeting of fluorophores to organelles in living cells.

K. Wirtz, T. Dansen, R. V. van Summeren, 2001, Experimental cell research.

Microsomal membranes contain phosphatidylcholine that equilibrates across the bilayer, and phosphatidylcholine that does not

K. Wirtz, J. Higgins, J. Hutson, 1985, FEBS letters.

Identification of the cDNA clone which encodes the 58-kDa protein containing the amino acid sequence of rat liver non-specific lipid-transfer protein (sterol-carrier protein 2). Homology with rat peroxisomal and mitochondrial 3-oxoacyl-CoA thiolases.

K. Wirtz, B. Ossendorp, G. P. V. van Heusden, 1991, European journal of biochemistry.

Phospholipid transfer proteins in perspective

K. Wirtz, 2006, FEBS letters.

Labeling of phospholipids in vesicles and human erythrocytes by photoactivable fatty acid derivatives.

K. Wirtz, A. van Amerongen, T. Berkhout, 1984, European journal of biochemistry.

Phosphoinositide signalling in nuclei of Friend cells: DMSO-induced differentiation reduces the association of phosphatidylinositol-transfer protein with the nucleus.

K. Wirtz, L. Cocco, A. Billi, 1997, Biochemical and biophysical research communications.

Increased cholesterol esterification in rat liver microsomes in purified non-specific phospholipid transfer protein.

K. Wirtz, B. J. Poorthuis, Karel W.A. Wirtz, 1982, Biochimica et biophysica acta.

Determination of the stability of the noncovalent phospholipid transfer protein-lipid complex by electrospray time-of-flight mass spectrometry.

K. Wirtz, A. Heck, B. Roelofsen, 2002, Biochemistry.

Inositides in the nucleus: taking stock of PLCβ1

K. Wirtz, S. Capitani, S. Rhee, 1998 .

Inositides in the nucleus: taking stock of PLC beta 1.

K. Wirtz, S. Capitani, S. Rhee, 1998, Advances in enzyme regulation.

Regulation of steroidogenesis in subclones of the MA-10 mouse Leydig tumor cell line

K. Wirtz, D. Stocco, M. Kilgore, 1990, Molecular and Cellular Endocrinology.

Phospholipid transfer proteins: From lipid monolayers to cells

K. Wirtz, 1991, Klinische Wochenschrift.

Purification of a Phosphatidylinositol 4‐Phosphate Kinase from Bovine Brain Membranes

K. Wirtz, W. Gispen, A. Moritz, 1990, Journal of neurochemistry.

Phosphatidylinositol transfer protein alpha regulates growth and apoptosis of NIH3T3 cells: involvement of a cannabinoid 1-like receptor.

K. Wirtz, J. Stam, B. Gadella, 2004, Journal of lipid research.

Cholesterol transfer from mitochondrial membranes and cells to human and rat serum lipoprotein fractions.

K. Wirtz, G. P. V. van Heusden, J. van Schijndel, 1989, Journal of lipid research.

Properties and modes of action of specific and non-specific phospholipid transfer proteins

K. Wirtz, T. Gadella, 1990, Experientia.

Semisynthesis and properties of a fluorescent phosphatidyl-inositol analogue containing a cis-parinaroyl moiety

K. Wirtz, P. Somerharju, 1982 .

Transfer of phosphatidylcholine between liposomes.

K. Wirtz, L. van Deenen, J. Hellings, 1974, European journal of biochemistry.

Isolation of a protein from beef liver which specifically stimulates the exchange of phosphatidylcholine.

K. Wirtz, L. van Deenen, H. Kamp, 1972, Biochimica et biophysica acta.

Activated neutrophils oxidize extracellular proteins of endothelial cells in culture: effect of nitric oxide donors.

K. Wirtz, D. V. Sakharov, J. Strosznajder, 2002, The Biochemical journal.

Phospholipid binding and transfer by the nonspecific lipid-transfer protein (sterol carrier protein 2). A kinetic model.

K. Wirtz, T. Gadella, 1994, European journal of biochemistry.

The low-affinity lipid binding site of the non-specific lipid transfer protein. Implications for its mode of action.

K. Wirtz, T. Gadella, 1991, Biochimica et biophysica acta.

Shape and lipid-binding site of the nonspecific lipid-transfer protein (sterol carrier protein 2): a steady-state and time-resolved fluorescence study.

K. Wirtz, P. Bastiaens, A. Visser, 1991, Biochemistry.

The non-specific lipid transfer protein (sterol carrier protein 2) from rat and bovine liver.

K. Wirtz, A. van Amerongen, T. Teerlink, 1985, Chemistry and physics of lipids.

The synthesis of sphingomyelin in the Morris hepatomas 7777 and 5123D is restricted to the plasma membrane.

K. Wirtz, G. P. V. van Heusden, A. van den Hill, 1985, Biochimica et biophysica acta.

Exchange of phospholipids between microsomes and inner and outer mitochondrial membranes of rat liver.

K. Wirtz, G. Scherphof, M. Blok, 1971, Biochimica et biophysica acta.

The amino acid sequence of rat liver non-specific lipid transfer protein (sterol carrier protein 2) is present in a high molecular weight protein: evidence from cDNA analysis.

K. Wirtz, B. Ossendorp, G. P. V. van Heusden, 1990, Biochemical and biophysical research communications.

Transfer of cholesterol and oxysterol derivatives by the nonspecific lipid transfer protein (sterol carrier protein 2): a study on its mode of action.

K. Wirtz, R. Demel, A. van Amerongen, 1989, Biochimica et biophysica acta.

Induction of a relatively fast transbilayer movement of phosphatidylcholine in vesicles. A 13CNMR study.

K. Wirtz, B. de Kruijff, 1977, Biochimica et biophysica acta.

Phosphatidylinositol 4-kinase and phosphatidylinositol-4-phosphate 5-kinase from bovine brain membranes.

K. Wirtz, A. Moritz, P. de Graan, 1992 .

Phosphatidylinositol transfer protein in murine embryonal carcinoma cells during retinoic acid‐induced differentiation

K. Wirtz, S. W. Laat, S. D. Laat, 1995, Development, growth & differentiation.

Peptide-based targeting of fluorophores to peroxisomes in living cells.

K. Wirtz, T. Dansen, E. Pap, 2001, Trends in cell biology.

Phosphatidylinositol Transfer Protein, Phosphoinositides and Cell Function

K. Wirtz, J. Westerman, G. Snoek, 1997 .

Structure and Function of Phosphoinositides in Membranes and Cells

K. Wirtz, A. Visser, B. Kruijff, 1987 .

Bradykinin-Induced Inositol Phosphate Metabolism in Human A431 Epidermoid Carcinoma Cells

K. Wirtz, I. Verlaan, W. Moolenaar, 1987 .

Inositol phosphate metabolism in bradykinin-stimulated human A431 carcinoma cells. Relationship to calcium signalling.

K. Wirtz, I. Verlaan, S. D. de Laat, 1987, The Biochemical journal.

Tissue distribution and subcellular localization of phosphatidylcholine transfer protein in rats as determined by radioimmunoassay.

K. Wirtz, M. Post, T. Teerlink, 1982, Biochimica et biophysica acta.

Phosphatidylcholine Transfer Protein: Model for Lipid-Protein Interactions and Probe for Membrane Research

K. Wirtz, B. Roelofsen, A. Visser, 1985 .

Modification of the Phosphatidylcholine‐Transfer Protein from Bovine Liver with Butanedione and Phenyiglyoxal

K. Wirtz, L. G. Lange, J. Westerman, 1981 .

Participation of soluble liver proteins in the exchange of membrane phospholipids.

D. B. Zilversmit, K. Wirtz, Donald B. Zilversmit, 1969, Biochimica et biophysica acta.

A phosphatidylinositol transfer protein α‐dependent survival factor protects cultured primary neurons against serum deprivation‐induced cell death

K. Wirtz, F. L. van Muiswinkel, G. Snoek, 2006, Journal of neurochemistry.

Reconstitution of steps in the constitutive secretory pathway in permeabilized cells. Secretion of glycosylated tripeptide and truncated sphingomyelin.

J. Rothman, K. Wirtz, J. Helms, 1990, The Journal of biological chemistry.

A fluorescence decay study of parinaroyl-phosphatidylinositol incorporated into artificial and natural membranes

K. Wirtz, A. Visser, J. Shute, 2004, European Biophysics Journal.

The membrane-embedded segment of cytochrome b5 as studied by cross-linking with photoactivatable phospholipids. II. The nontransferable form.

H. Khorana, K. Wirtz, R. Radhakrishnan, 1983, The Journal of biological chemistry.

Tissue-specific distribution of a peroxisomal 46-kDa protein related to the 58-kDa protein (sterol carrier protein x; sterol carrier protein 2/3-oxoacyl-CoA thiolase).

K. Wirtz, W. Voorhout, B. Ossendorp, 1996, Archives of biochemistry and biophysics.

High-affinity binding of very-long-chain fatty acyl-CoA esters to the peroxisomal non-specific lipid-transfer protein (sterol carrier protein-2).

F. Wouters, K. Wirtz, R. Wanders, 1999, The Biochemical journal.

cDNA cloning and tissue-specific expression of the phosphatidylcholine transfer protein gene.

K. Wirtz, A. Smith, P. Borst, 1996, The Biochemical journal.

Phospholipid transfer proteins.

K. Wirtz, 1991, Annual review of biochemistry.

Cooperativity of phosphatidylinositol transfer protein and phospholipase D in secretory vesicle formation from the TGN – phosphoinositides as a common denominator?

K. Wirtz, W. Huttner, B. Bouma, 1997, FEBS letters.

Application of fluorescent phospholipid analogues to studies on phospholipid transfer proteins.

K. Wirtz, P. Somerharju, P. Somerharju, 1990, Sub-cellular biochemistry.

The binding of phosphatidylcholine to the phosphatidylcholine transfer protein: affinity and role in folding.

K. Wirtz, B. Roelofsen, J. Brouwers, 2001, Chemistry and physics of lipids.

Identification of an essential lysine residue in the phosphatidylcholine-transfer protein from bovine liver by modification with phenylisothiocyanate.

K. Wirtz, D. van Loon, J. Westerman, 1986, European journal of biochemistry.

Signalling Mechanisms — from Transcription Factors to Oxidative Stress

K. Wirtz, L. Packer, 1995, NATO ASI Series.

Transfer of phospholipids between membrane

K. Wirtz, 1974 .

Phosphatidylcholine exchange protein from beef liver.

K. Wirtz, R. Demel, L. van Deenen, 1973, Nature: New biology.

Phospholipid exchange proteins in synaptosome and myelin fraction from rat brain

K. Wirtz, J. Jolles, J. Westerman, 1976, Nature.

Erythrocyte band 3 protein strongly interacts with phosphoinositides

K. Wirtz, A. Visser, D. Schubert, 1994, FEBS letters.

Phosphoinositide-protein interactions of the plasma-membrane Ca2(+)-transport ATPase as revealed by fluorescence energy transfer.

K. Wirtz, L. Raeymaekers, F. Wuytack, 1991, Biochimica et biophysica acta.

New Developments in Lipid-Protein Interactions and Receptor Function

K. Wirtz, J. Gustafsson, L. Packer, 1993, NATO ASI Series.

Transfer of phospholipids between subcellular fractions of the lung

K. Wirtz, M. Engle, L. V. van Golde, 1978, FEBS letters.

Molecular Mechanisms of Signalling and Membrane Transport

K. Wirtz, 1997, NATO ASI Series.

The primary structure of the phosphatidylcholine-exchange protein from bovine liver. Isolation and characterization of the staphylococcal protease peptides and the amino-acid sequence of the N-terminal half (residues 1--122).

K. Wirtz, P. Moonen, J. Westerman, 2005, European journal of biochemistry.

On membrane phospholipids and protein-lipid association

K. Wirtz, B. Roelofsen, L. van Deenen, 1982 .

Membrane Receptors, Dynamics, and Energetics

K. Wirtz, 1987, NATO ASI Series.

Delipidation of the phosphatidylcholine exchange protein from beef liver by detergents.

K. Wirtz, L. van Deenen, H. Kamp, 1975, Biochimica et biophysica acta.

Identification of the lipid-binding site of phosphatidylcholine-transfer protein with phosphatidylcholine analogs containing photoactivable carbene precursors.

H. Khorana, K. Wirtz, R. Radhakrishnan, 1983, European journal of biochemistry.

PHOSPHOLIPIDS. SOME RECENT STUDIES ON LIPID-PROTEIN INTERACTION IN RELATION TO BIOMEMBRANES

K. Wirtz, B. Roelofsen, A. Verkleij, 1974 .

Corticotropin-(1--24)-tetracosapeptide affects protein phosphorylation and polyphosphoinositide metabolism in rat brain.

K. Wirtz, J. Jolles, W. Gispen, 1981, The Biochemical journal.

Pituitary hormones influence polyphosphoinositide metabolism in rat brain

K. Wirtz, J. Jolles, P. Schotman, 1979, FEBS letters.

Lipid-Protein Interactions in Biological Membranes. Spin-Label Studies

K. Wirtz, J. Davoust, P. Devaux, 1980 .

Characterization of phosphatidylinositol-4-phosphate 5-kinase activities from bovine brain membranes.

K. Wirtz, B. Payrastre, W. Gispen, 1993, Biochimica et biophysica acta.

Exchange of phospholipids between liver mitochondria and microsomes in vitro.

D. B. Zilversmit, K. Wirtz, 1968, The Journal of biological chemistry.

Free fatty acids and esters can be immobilized by receptor rich membranes from Torpedo marmorata but not phospholipid acyl chains.

K. Wirtz, A. Rousselet, P. Devaux, 1979, Biochemical and biophysical research communications.

Lipid-protein interaction in the phosphatidylcholine exchange protein.

K. Wirtz, P. Devaux, P. Moonen, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Transbilayer distribution and mobility of phosphatidylcholine in intact erythrocyte membranes. A study with phosphatidylcholine exchange protein.

K. Wirtz, G. van Meer, G. Meer, 1980, European journal of biochemistry.

Some properties of phosphatidylcholine exchange protein purified from beef liver

K. Wirtz, L. M. Deenen, H. Kamp, 1973 .

Phosphatidylcholine transfer protein from bovine liver contains highly unsaturated phosphatidylcholine species

K. Wirtz, J. Westerman, W. Heerma, 1996, FEBS letters.

The exchange of molecular species of phosphatidylcholine between mitochondria and microsomes of rat liver.

K. Wirtz, L. van Deenen, L. V. van Golde, 1970, Biochimica et biophysica acta.

[52] Phosphatidylcholine transfer protein from bovine liver

K. Wirtz, J. Westerman, H. Kamp, 1983 .

Interaction of C-reactive protein with artificial phosphatidylcholine bilayers

K. Wirtz, J. Volanakis, 1979, Nature.

Action of phospholipases on the phosphatidylcholine exchange protein from beef liver.

K. Wirtz, L. van Deenen, E. Sprengers, 1975, Biochimica et biophysica acta.

PHOSPHOLIPASES AND MONOLAYERS AS TOOLS IN STUDIES ON MEMBRANE STRUCTURE

K. Wirtz, B. Roelofsen, A. Verkleij, 1976 .

A new fluorimetric method to measure protein-catalyzed phospholipid transfer using 1-acyl-2-parinaroylphosphatidylcholine.

K. Wirtz, P. Somerharju, H. Brockerhoff, 1981, Biochimica et biophysica acta.

Phosphatidylcholine exchange protein catalyzes the net transfer of phosphatidylcholine to model membranes.

K. Wirtz, P. Devaux, A. Bienvenue, 1980, Biochemistry.

Phospholipid-exchange proteins: a new class of intracellular lipoproteins

K. Wirtz, L. Deenen, 1977 .

Phosphatidylinositol exchange protein. Effects of membrane structure on activity and evidence for a ping-pong mechanism.

K. Wirtz, G. M. Helmkamp, L. van Deenen, 1976, Archives of biochemistry and biophysics.

A study on phospholipid exchange proteins present in the soluble fractions of beef liver and brain.

K. Wirtz, L. van Deenen, B. Zegers, 1973, Biochimica et biophysica acta.

Influence of membrane phosphatidylinositol content on the activity of bovine brain phospholipid transfer protein

K. Wirtz, G. M. Helmkamp, L. van Deenen, 1974, FEBS letters.

Lipids and membranes: past, present and future.

K. Wirtz, B. Roelofsen, J. O. D. Kamp, 1986 .

Chapter 9 – Intracellular Phospholipid Transfer Proteins

K. Wirtz, B. Ossendorp, G. Snoek, 1994 .

Determination of nonspecific lipid transfer protein in rat tissues and Morris hepatomas by enzyme immunoassay.

K. Wirtz, T. Teerlink, G. P. V. van Heusden, 1984, Biochimica et biophysica acta.

Phospholipid transfer activities in Morris hepatomas and the specific contribution of the phosphatidylcholine exchange protein.

K. Wirtz, T. Teerlink, K. Hostetler, 1980, Biochimica et biophysica acta.

Phospholipid transfer proteins in rat lung. Identification of a protein specific for phosphatidylglycerol.

K. Wirtz, M. Post, J. J. Batenburg, 1980, The Journal of biological chemistry.

Affinity chromatography of the phosphatidylcholine exchange protein from bovine liver.

K. Wirtz, L. I. Barsukov, L. Bergelson, 1978, Biochimica et biophysica acta.

Some properties of phospholipid exchange proteins from rat liver.

K. Wirtz, R. Lumb, L. M. Deenen, 1976, European journal of biochemistry.

The protein-mediated transfer of phosphatidylcholine between membranes. The effect of membrane lipid composition and ionic composition of the medium.

K. Wirtz, R. Demel, H. Kamp, 1976, European journal of biochemistry.

A Sphingomyelin-transferring Protein from Chicken Liver. USE OF PYRENE-LABELED PHOSPHOLIPID (*)

K. Wirtz, P. Somerharju, Johanna L.P.M. Timmermans-Hereijgers, 1995, The Journal of Biological Chemistry.

Clofibrate-induced relocation of phosphatidylcholine transfer protein to mitochondria in endothelial cells.

K. Wirtz, B. Roelofsen, A. D. de Brouwer, 2002, Experimental cell research.

Identification of the newly discovered 58kDa peroxisomal thiolase SCPx as the main thiolase involved in both pristanic acid and trihydroxycholestanoic acid oxidation: Implications for peroxisomal β-oxidation disorders

F. Wouters, K. Wirtz, S. Denis, 1998, Journal of Inherited Metabolic Disease.

The precursor form of the rat liver non‐specific lipid‐transfer protein, expressed in Escherichia coli, has lipid transfer activity

K. Wirtz, B. Ossendorp, T. Geijtenbeek, 1992, FEBS letters.

The anti-apoptotic activity associated with phosphatidylinositol transfer protein alpha activates the MAPK and Akt/PKB pathway.

K. Wirtz, J. Goedhart, T. Gadella, 2008, Biochimica et biophysica acta.

Phosphatidylinositol transfer proteins: from closed for transport to open for exchange.

K. Wirtz, P. Gros, A. Schouten, 2006, Advances in enzyme regulation.

Overexpression of phosphatidylinositol transfer protein beta in NIH3T3 cells has a stimulatory effect on sphingomyelin synthesis and apoptosis.

K. Wirtz, C. van Tiel, G. Snoek, 2004, Biochimica et biophysica acta.

The structure of phosphatidylinositol transfer protein α reveals sites for phospholipid binding and membrane association with major implications for its function

K. Wirtz, P. Gros, A. Schouten, 2002, FEBS letters.

Structure of apo‐phosphatidylinositol transfer protein α provides insight into membrane association

K. Wirtz, B. Agianian, P. Gros, 2002, The EMBO journal.

Phosphatidyl Inositol Transfer Proteins

K. Wirtz, G. Snoek, 2002 .

Endoplasmic reticulum resident proteins of normal human dermal fibroblasts are the major targets for oxidative stress induced by hydrogen peroxide.

K. Wirtz, J. Celis, J. Post, 2002, The Biochemical journal.

"Wages of fear": transient threefold decrease in intracellular ATP level imposes apoptosis.

K. Wirtz, B. Chernyak, V. Skulachev, 2004, Biochimica et biophysica acta.

Biological Signal Transduction

K. Wirtz, E. Ross, 1991, NATO ASI Series.

Fluorescent fatty acid to monitor reactive oxygen in single cells.

J A Post, K. Wirtz, G. Drummen, 2000, Methods in enzymology.

Defective peroxisomal catabolism of branched fatty acyl coenzyme A in mice lacking the sterol carrier protein-2/sterol carrier protein-x gene function.

F. Wouters, K. Wirtz, S. Denis, 1998, Genes & development.

Regulation of sterol carrier protein2 (SCP2) levels in the soluble fraction of rat Leydig cells. Kinetics and the possible role of calcium influx

K. Wirtz, A. Amerongen, M. H. Noort, 1988, Molecular and Cellular Endocrinology.

Sterol carrier protein 2 (non-specific lipid transfer protein) is localized in membranous fractions of Leydig cells and Sertoli cells but not in germ cells.

K. Wirtz, B. Ossendorp, J. Orly, 1992, Biochimica et biophysica acta.

Partial purification of phospholipid exchange protein from beef heart

D. B. Zilversmit, K. Wirtz, D.B. Zilversmit, 1970, FEBS letters.

FRET microscopy demonstrates molecular association of non‐specific lipid transfer protein (nsL‐TP) with fatty acid oxidation enzymes in peroxisomes

T M Jovin, F. Wouters, K. Wirtz, 1998, The EMBO journal.

The non-specific lipid-transfer protein (sterol carrier protein 2) and its relationship to peroxisomes.

K. Wirtz, B. Ossendorp, 1993, Biochimie.

The human MDR3 P‐glycoprotein promotes translocation of phosphatidylcholine through the plasma membrane of fibroblasts from transgenic mice

K. Wirtz, B. Roelofsen, P. Borst, 1994, FEBS letters.

Quantitative analysis of lipid-lipid and lipid-protein interactions in membranes by use of pyrene-labeled phosphoinositides.

K. Wirtz, A. Visser, A. van Hoek, 1995, Biochemistry.

Activity of phosphatidylinositol transfer protein is sensitive to ethanol and membrane curvature.

K. Wirtz, H. Komatsu, T. Taraschi, 2000, The Biochemical journal.

A new high-yield procedure for the purification of the non-specific phospholipid transfer protein from rat liver.

K. Wirtz, J. Glatz, B. J. Poorthuis, 1981, Biochimica et biophysica acta.

The use of phenobarbital and carbon tetrachloride to examine liver phospholipid exchange in intact rats.

D. B. Zilversmit, K. Wirtz, 1969, Biochimica et biophysica acta.

Binding of phospholipids to the phosphatidylinositol transfer protein from bovine brain as studied by steady-state and time-resolved fluorescence spectroscopy.

K. Wirtz, A. Visser, P. V. van Paridon, 1987, Biochimica et biophysica acta.

Static and time-resolved fluorescence studies of fluorescent phosphatidylcholine bound to the phosphatidylcholine transfer protein of bovine liver.

K. Wirtz, A. Visser, T. Berkhout, 1984, Biochemistry.

The Complete Primary Structure of the Phosphatidylcholine‐Transfer Protein from Bovine Liver

K. Wirtz, P. Moonen, J. Westerman, 1981 .

The complete primary structure of the phosphatidylcholine-transfer protein from bovine liver. Isolation and characterization of the cyanogen bromide peptides.

K. Wirtz, P. Moonen, J. Westerman, 1981, European journal of biochemistry.

Photodynamic treatment and H2O2-induced oxidative stress result in different patterns of cellular protein oxidation.

K. Wirtz, A. Bunschoten, Huib van Weelden, 2003, European journal of biochemistry.

The anti-apoptotic MAP kinase pathway is inhibited in NIH3T3 fibroblasts with increased expression of phosphatidylinositol transfer protein beta.

K. Wirtz, C. van Tiel, G. Snoek, 2007, Biochimica et biophysica acta.

The phosphatidylcholine-transfer protein catalyzed import of phosphatidylcholine into isolated rat liver mitochondria.

K. Wirtz, B. de Kruijff, K. Nicolay, 1990, Biochimica et biophysica acta.

Enzymatic synthesis of pyrene-labeled polyphosphoinositides and their behavior in organic solvents and phosphatidylcholine bilayers.

K. Wirtz, A. Moritz, T. Gadella, 1990, Biochemistry.

Synthesis of phosphatidylinositol 4,5-bisphosphate in the endoplasmic reticulum of Chinese hamster ovary cells.

K. Wirtz, J. Helms, K. D. de Vries, 1991, The Journal of biological chemistry.

(poly)Phosphoinositide phosphorylation is a marker for plasma membrane in Friend erythroleukaemic cells

K. Wirtz, B. Roelofsen, A. Rawyler, 1982, FEBS letters.

The primary structure of the nonspecific lipid transfer protein (sterol carrier protein 2) from bovine liver.

K. Wirtz, J. Westerman, 1985, Biochemical and biophysical research communications.

Kinetic model of the protein-mediated phosphatidylcholine exchange between single bilayer liposomes.

K. Wirtz, G. M. Helmkamp, A. Van den Besselaar, 1975, Biochemistry.

Nonspecific lipid transfer protein (sterol carrier protein 2) is bound to rat liver mitochondria: its role in spontaneous intermembrane phospholipid transfer.

K. Wirtz, A. van Amerongen, E. Quagliariello, 1986, Biochimica et biophysica acta.

A comparative fluorescence polarization study of cis-parinaroyl-phosphatidylcholine and diphenylhexatriene in membranes containing different amounts of cholesterol.

K. Wirtz, B. Roelofsen, F. Kuypers, 1984, Chemistry and physics of lipids.

Prolonged lipid oxidation after photodynamic treatment. Study with oxidation‐sensitive probe C11‐BODIPY581/591

K. Wirtz, D V Sakharov, D. V. Sakharov, 2005, FEBS letters.

The Golgi Localization of Phosphatidylinositol Transfer Protein β Requires the Protein Kinase C-dependent Phosphorylation of Serine 262 and Is Essential for Maintaining Plasma Membrane Sphingomyelin Levels*

K. Wirtz, J. Westerman, C. van Tiel, 2002, The Journal of Biological Chemistry.

Effect of nonspecific phospholipid transfer protein on cholesterol esterification in microsomes from Morris hepatomas.

K. Wirtz, G. P. V. van Heusden, K. Hostetler, 1983, Cancer research.

Phospholipid transfer proteins revisited.

K. Wirtz, 1997, The Biochemical journal.

Chinese hamster ovary cells deficient in peroxisomes lack the nonspecific lipid transfer protein (sterol carrier protein 2).

K. Wirtz, C. Raetz, G. P. V. van Heusden, 1990, Journal of Biological Chemistry.

Characterization of mouse phosphatidylinositol transfer protein expressed in Escherichia coli.

K. Wirtz, J. Westerman, G. Snoek, 1994, Biochimica et biophysica acta.

Nonspecific lipid transfer protein from rat liver.

K. Wirtz, B. J. Poorthuis, 1983, Methods in enzymology.

Properties of Phospholipid Transfer Proteins

K. Wirtz, R. Akeroyd, 1982 .

The occurrence of soluble and membrane-bound non-specific lipid transfer protein (sterol carrier protein 2) in rat tissues.

K. Wirtz, G. P. V. van Heusden, K. Bos, 1990, Biochimica et biophysica acta.

The subcellular distribution of the nonspecific lipid transfer protein (sterol carrier protein 2) in rat liver and adrenal gland.

K. Wirtz, A. van Amerongen, J. Orly, 1989, Biochimica et biophysica acta.

Intracellular redistribution of SCP2 in Leydig cells after hormonal stimulation may contribute to increased pregnenolone production.

K. Wirtz, A. van Amerongen, F. Rommerts, 1988, Biochemical and biophysical research communications.

Purification of nonspecific lipid transfer protein (sterol carrier protein 2) from human liver and its deficiency in livers from patients with cerebro-hepato-renal (Zellweger) syndrome.

K. Wirtz, J. Helms, A. van Amerongen, 1987, Biochimica et biophysica acta.

Cholesterol metabolism and sterol carrier protein-2 (non-specific lipid transfer protein).

K. Wirtz, A. Beynen, M. Geelen, 1987, The International journal of biochemistry.

Ultrastructural localization of a peroxisomal protein in rat liver using the specific antibody against the non-specific lipid transfer protein (sterol carrier protein 2).

K. Wirtz, A. Verkleij, T. Teerlink, 1985, Biochimica et biophysica acta.

Evidence for a Link Between Peroxisomes and the Nonspecific Lipid Transfer Protein (Sterol Carrier Protein 2) in Rat and Human Liver

K. Wirtz, J. Helms, A. Amerongen, 1987 .

Ratio‐fluorescence microscopy of lipid oxidation in living cells using C11‐BODIPY581/591

V. J. Winter, J A Post, J A Op den Kamp, 1999, FEBS letters.

Regulation of the activity of phosphatidylcholine transfer protein by vesicle phosphatidic acid and membrane curvature: a fluorescence study using 2-parinaroylphosphatidylcholine

K. Wirtz, B. Kruijff, T. Berkhout, 1984 .

Chemical modification of methionine residues of the phosphatidylcholine transfer protein from bovine liver. A spin-label study.

K. Wirtz, E. Quagliariello, D. van Loon, 1985, European journal of biochemistry.

Properties and Function of Phosphatidylcholine Transfer Proteins

K. Wirtz, T. Teerlink, R. Akeroyd, 1985 .

Overexpression of Phosphatidylinositol Transfer Protein α in NIH3T3 Cells Activates a Phospholipase A*

D. Corda, K. Wirtz, C. Berrie, 1999, The Journal of Biological Chemistry.

Evidence that mammalian phosphatidylinositol transfer protein regulates phosphatidylcholine metabolism.

R. J. Alexander, K. Wirtz, P. Walden, 1998, The Biochemical journal.

The effect of polyphosphoinositides and phosphatidic acid on the phosphatidylinositol transfer protein from bovine brain: a kinetic study.

K. Wirtz, T. Gadella, P. V. van Paridon, 1988, Biochimica et biophysica acta.

Phosphatidylinositol transfer protein from bovine brain. Substrate specificity and membrane binding properties.

K. Wirtz, P. Somerharju, P. V. van Paridon, 1983, Biochimica et biophysica acta.

Kinetic analysis of the interaction of the phosphatidylcholine exchange protein with unilamellar vesicels and multilamellar liposomes.

G. Vriend, K. Wirtz, J. Westerman, 1979, European journal of biochemistry.

Interaction of the phosphatidylcholine exchange protein with phospholipids. A fluorescence and circular dichroism study.

K. Wirtz, P. Moonen, 1977, European journal of biochemistry.

Proteolytic activation of a bovine brain protein with phosphatidylinositol transfer activity

K. Wirtz, T. Gadella, J. Westerman, 1990, FEBS Letters.

Prediction of secondary structural elements in the phosphatidylcholine-transfer protein from bovine liver.

G. Vriend, K. Wirtz, J. Lenstra, 1982, European journal of biochemistry.

Rapid replenishment of sphingomyelin in the plasma membrane upon degradation by sphingomyelinase in NIH3T3 cells overexpressing the phosphatidylinositol transfer protein beta.

K. Wirtz, C. Luberto, Y. Hannun, 2000, The Biochemical journal.

PHOSPHATIDYLINOSITOL TRANSFER PROTEIN AND MEMBRANE VESICLE FLOW

K. Wirtz, G. Snoek, 1993 .

Fluorescent Analogues of Phosphoinositides in Studies on Lipid-Protein Interactions and Membrane Dynamics

K. Wirtz, A. Visser, P. Somerharju, 1991 .

On the relationship between the dual specificity of the bovine brain phosphatidylinositol transfer protein and membrane phosphatidylinositol levels.

K. Wirtz, P. Somerharju, T. Gadella, 1987, Biochimica et biophysica acta.

Fluorescently labeled phosphatidylinositol transfer protein isoforms (alpha and beta), microinjected into fetal bovine heart endothelial cells, are targeted to distinct intracellular sites.

K. Wirtz, P. Bastiaens, T. Jovin, 1996, Experimental cell research.

An isoform of the phosphatidylinositol-transfer protein transfers sphingomyelin and is associated with the Golgi system.

K. Wirtz, P. Somerharju, P. Somerharju, 1995, The Biochemical journal.

A novel acidic form of the phosphatidylinositol transfer protein is preferentially retained in permeabilized Swiss mouse 3T3 fibroblasts.

K. Wirtz, G. Snoek, A. Momchilova-Pankova, 1994, Experimental Cell Research.

Phosphatidylinositol-transfer protein and cellular phosphatidylinositol metabolism.

K. Wirtz, P. Somerharju, P. V. van Paridon, 1987, Biochemical Society Transactions.

Polyphosphoinositides undergo charge neutralization in the physiological pH range: a 31P-NMR study.

K. Wirtz, B. de Kruijff, R. Ouwerkerk, 1986, Biochimica et biophysica acta.

Determination of the hydrophobic binding site of phosphatidylcholine exchange protein with photosensitive phosphatidylcholine.

K. Wirtz, H. Haagsman, L. van Deenen, 1979, European journal of biochemistry.

IDENTIFICATION OF THE LIPID BINDING SITE OF THE PHOSPHATIDYLCHOLINE EXCHANGE PROTEIN WITH A PHOTOSENSITIVE NITRENE AND CARBENE PRECURSOR OF PHOSPHATIDYLCHOLINE

H. Khorana, K. Wirtz, R. Radhakrishnan, 1980, Annals of the New York Academy of Sciences.

Role of the Phosphatidylinositol Transfer Protein in Intracellular Membrane Traffic

K. Wirtz, P. Bastiaens, G. Snoek, 1997 .

Intracellular Localization and Mechanisms of Regulation of Phosphatidylinositol Transfer Protein in Swiss Mouse 3T3 Cells

K. Wirtz, G. Snoek, 1994 .

Properties of phosphoinositides in membranes

K. Wirtz, T. Gadella, J. Verbist, 1991 .

Phospholipid-transfer proteins and their mRNAs in developing rat lung and in alveolar type-II cells.

K. Wirtz, B. Ossendorp, M. Houweling, 1994, The Biochemical journal.

Phosphatidylcholine exchange protein from beef liver.

K. Wirtz, H. Kamp, 1974, Methods in enzymology.

Characterization of the non-specific lipid transfer protein EP2 from carrot (Daucus carota L.)

K. Wirtz, P. Sterk, S. Vries, 1993, Molecular and Cellular Biochemistry.

Peroxisomes in human fibroblasts have a basic pH

K. Wirtz, R. Wanders, T. Dansen, 1999, Nature Cell Biology.

Human erythrocyte membranes are fluid down to −5°C

M. Bloom, K. Wirtz, B. Maraviglia, 1982 .

Quantitation of the interaction of protein kinase C with diacylglycerol and phosphoinositides by time-resolved detection of resonance energy transfer.

K. Wirtz, P. Bastiaens, A. Visser, 1993, Biochemistry.

Measurement of phosphatidylcholine transfer protein in rat liver and hepatomas by radioimmunoassay.

K. Wirtz, T. Teerlink, T. van der Krift, 1981, Biochimica et biophysica acta.

Human erythrocyte membranes are fluid down to -5 degrees C.

K. Wirtz, B. Maraviglia, J. Westerman, 1982, Biochimica et biophysica acta.

Detection of protein oxidation in rat-1 fibroblasts by fluorescently labeled tyramine.

K. Wirtz, D. van der Vlies, E. Pap, 2001, Biochemistry.

PROTEIN-MEDIATED LIPID TRANSFER BETWEEN MONOLAYERS AND BILAYERS

K. Wirtz, R. Demel, R. Jackson, 1984 .

Complete exchange of phospholipids between microsomes and plasma lipoproteins mediated by liver phospholipid‐exchange proteins

K. Wirtz, R. Jackson, J. Westerman, 1978, FEBS letters.

Identification of the non-specific lipid-transfer protein (sterol carrier protein 2) in peroxisomes of lung type II cells.

K. Wirtz, W. Voorhout, B. Ossendorp, 1994, Biochemical and biophysical research communications.

Phosphatidylinositol transfer protein α regulates growth and apoptosis of NIH3T3 cells Published, JLR Papers in Press, May 16, 2004. DOI 10.1194/jlr.M400127-JLR200

K. Wirtz, J. Stam, B. Gadella, 2004, Journal of Lipid Research.