J. Järv

发表

Statistical analysis of protein kinase specificity determinants

N. Blom, S. Brunak, A. Kreegipuu, 1998, FEBS letters.

Single-subunit allostery in the kinetics of pe ptide phosphorylation by protein kinase A

J. Järv, A. Kuznetsov, 2008 .

Linear free energy relationships in cAMP-dependent protein kinase reactions with synthetic substrates

J. Järv, U. Ragnarsson, 1991 .

Computational modeling of strained alkenes: Choosing the right computational model

J. Järv, P. Burk, Ott Kekišev, 2017 .

Stereochemical aspects of cholinesterase catalysis

J. Järv, 1984 .

Oxidative bromination of non-activated aromatic compounds with AlBr3/KNO3 mixture

J. Järv, I. Rahu, 2019, Chemical Papers.

The arrangement of substrate and organophosphorus-inhibitor leaving groups in acetylcholinesterase active site.

J. Järv, A. Aaviksaar, N. Godovikov, 1977, The Biochemical journal.

Effect of two simultaneous aza-β3-amino acid substitutions on recognition of peptide substrates by cAMP dependent protein kinase catalytic subunit.

J. Järv, A. Kuznetsov, M. Baudy-Floc’h, 2011, Bioorganic chemistry.

ACE2 peptide fragment interacts with several sites on the SARS-CoV-2 spike protein S1

J. Järv, A. Kuznetsov, Ü. Langel, 2020, bioRxiv.

Mechanism of modulation of [3H]raclopride binding to dopaminergic receptors in rat striatal membranes by sodium ions

K. Fuxe, J. Järv, A. Rinken, 1997, Neurochemistry International.

Small Structural Changes at theN‐position of the Tropane Core Control the Mechanism of Nortropane Derivatives Binding to Dopamine Transporter

J. Järv, S. Kukk, 2018, ChemistrySelect.

Comparison of various coupling reagents in solid-phase aza-peptide synthesis

J. Järv, Meeli Arujõe, A. Ploom, 2017 .

Nβ-methylation changes the recognition pattern of aza-β3-amino acid containing peptidomimetic substrates by protein kinase A

J. Järv, A. Kuznetsov, M. Baudy-Floc’h, 2011, Organic and medicinal chemistry letters.

Mapping the ACE2 binding site on the SARS-CoV-2 spike protein S1: molecular recognition pattern

J. Järv, A. Kuznetsov, 2020, Proceedings of the Estonian Academy of Sciences.

Steric Parameters for Substituents Bound to Atoms of Silicon and Some Other Elements of the Third Period

J. Järv, A. Tuulmets, A. Ploom, 2010 .

Peptide phosphorylation by calcium-dependent protein kinase from maize seedlings.

J. Järv, M. Loog, K. Sak, 2000, European journal of biochemistry.

Novel Galanin Receptor Subtype Specific Ligand in Depression Like Behavior

J. Järv, I. Saar, Ü. Langel, 2012, Neurochemical Research.

Novel galanin receptor subtype specific ligands in feeding regulation

J. Järv, I. Saar, Ü. Langel, 2011, Neurochemistry International.

A novel GalR2-specific peptide agonist

J. Järv, I. Saar, Ü. Langel, 2009, Neuropeptides.

Kinetic mechanism of dopamine transporter interaction with 1-(2-(bis-(4-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)piperazine (GBR 12909)

J. Järv, V. Stepanov, 2008, Neurochemistry International.

Interaction of tritium-labelled dopamine transporter inhibitor PE2I with mice striatal membrane fragments

J. Järv, V. Stepanov, 2006, Proceedings of the Estonian Academy of Sciences. Chemistry.

Kinetic evidence for different mechanisms of interaction of black mamba toxins MTα and MTβ with muscarinic receptors

J. Järv, K. Åkerman, E. Karlsson, 2001 .

Substrate specificity of protein kinase C studied with peptides containing D-amino acid residues.

J. Järv, P. Ekman, L. Engström, 1993, Journal of biochemistry.

Substrate-binding sites in acetylcholinesterase.

J. Järv, F. Hucho, C. Weise, 1991, Trends in pharmacological sciences.

Fluidity of detergent micelles plays an important role in muscarinic receptor solubilization

J. Järv, A. Rinken, A. Kõiv, 1990, Journal of Biosciences.

Alumina coating of polyvinylidene fluoride (PVDF) surface in liquid phase

J. Järv, T. Tenno, J. Liiv, 2014 .

Effect of strain on gas-phase basicity of (E)-1-methyl-2-(1-methyl-2-adamantylidene)adamantane

D. Lenoir, J. Järv, P. Burk, 2015 .

Differentiating between drugs with short and long residence times

J. Järv, S. Kukk, 2016 .

Adenosine-derived non-phosphate antagonists for P2Y(1) purinoceptors.

J. Järv, M. Kelve, J. Subbi, 2000, Biochemical and biophysical research communications.

Kinetic analysis of cooperativity of phosphorylated L-type pyruvate kinase

J. Järv, I. Faustova, 2006, Proceedings of the Estonian Academy of Sciences. Chemistry.

A model of oximeter-based enzyme electrode

J. Järv, T. Tenno, A. Rinken, 1996 .

Similar dynamics of G-protein coupled receptors molecules in response to antagonist binding

J. Järv, A. Oras, 2005, Neuroscience Letters.

Only pyrimidinoceptors are functionally expressed in mouse neuroblastoma cell lines.

J. Järv, M. Kelve, K. Sak, 1999, Molecular cell biology research communications : MCBRC.

Thermal Stability of Dopamine Transporters

J. Järv, V. Stepanov, S. Kukk, 2015, The Journal of Membrane Biology.

Slow isomerization step in the interaction between mouse dopamine transporter and dopamine re-uptake inhibitor N-(3-iodoprop-2E-enyl)-2β-carbo-[3H]methoxy-3β-(4′-methylphenyl)nortropane

J. Järv, V. Stepanov, 2006, Neuroscience Letters.

Salt effects on cholinesterase-catalyzed hydrolysis of acetylcholine

J. Järv, T. Kesvatera, A. Langel, 1990 .

Chemical functionalization of a polyvinylidene fluoride surface

J. Järv, V. Sammelselg, T. Tenno, 2013 .

Synthesis of N-protected erythro-phenylalanylepoxides

J. Järv, Ü. Langel, M. Zetterström, 1995 .

A Convenient Methanolysis in the Synthesis of Carfentanyl

J. Järv, A. Mastitski, E. Vellemäe, 2018, Organic Preparations and Procedures International.

Regioselective One-pot Synthesis of N-Fmoc/Cbz, N’’-Boc Protected Indol-(3)-ylmethylhydrazines

J. Järv, Tõiv Haljasorg, A. Mastitski, 2020 .

One-Pot Synthesis of Protected Benzylhydrazines from Acetals

J. Järv, Tõiv Haljasorg, A. Mastitski, 2018, Organic Preparations and Procedures International.

One-Pot Synthesis of Fmoc- and Boc-Protected Aza-Methionine Precursors from 2-Methylthioacetaldehyde Dimethyl Acetal

J. Järv, A. Mastitski, 2014 .

Synthesis of Nω,Νω–di-Boc-3-guanidylpropanal - An Important Reagent for Synthesis of Aza-Arg Precursors

J. Järv, A. Mastitski, A. Troska, 2021, Organic Preparations and Procedures International.

One-pot Synthesis of Protected Alkylhydrazines from Acetals and Ketals. Scope and Limitations

J. Järv, Tõiv Haljasorg, A. Mastitski, 2015 .

Synthesis of aza-phenylalanine , aza-tyrosine , and aza-tryptophan precursors via hydrazine alkylation

J. Järv, Tõiv Haljasorg, K. Kipper, 2015 .

Regioselective Benzylation of N-Boc-N’-COCF3-protected Hydrazine

J. Järv, A. Mastitski, Kerli Tali, 2022, Organic Preparations and Procedures International.

Aza-peptides: expectations and reality

J. Järv, Meeli Arujõe, A. Ploom, 2022, Proceedings of the Estonian Academy of Sciences.

Potassium iodide catalysis in the alkylation of protected hydrazines

J. Järv, A. Kruve, A. Abramov, 2017 .

Synthesis of the Fmoc-aza-Arg(Boc)2 precursor via hydrazine alkylation

J. Järv, K. Kisseljova, A. Mastitski, 2014 .

Aza-beta(3)-amino acid containing peptidomimetics as cAMP-dependent protein kinase substrates.

J. Järv, A. Kuznetsov, M. Baudy-Floc’h, 2010, Bioorganic chemistry.

Kinetic study of aza-amino acid incorporation into peptide chains: Influence of the steric effect of the side chain

J. Järv, H. Härk, P. Burk, 2022, Tetrahedron.

Steric impact of aza-amino acid on solid-phase aza-peptide bond synthesis

J. Järv, Meeli Arujõe, A. Ploom, 2021 .

Rate and equilibrium constants for Grignard reaction with alkoxysilanes and ketones

J. Järv, D. Panov, A. Tuulmets, 2008 .

Ultrasonic detection of hydrophobic interactions: a quantitative approach

Giancarlo Cravotto, Jaak Järv, J. Järv, 2008 .

Kinetics of the grignard reaction with silanes in diethyl ether and ether-toluene mixtures.

J. Järv, Meeri Sassian, D. Panov, 2003, The Journal of organic chemistry.

Role of water in determining organic reactivity in aqueous binary solvents

J. Järv, S. Salmar, T. Tenno, 2012 .

Reaction kinetics and solubility in water‐organic binary solutions are governed by similar solvation equilibria

J. Järv, A. Kuznetsov, S. Salmar, 2016 .

Kinetic sonication effects in light of molecular dynamics simulation of the reaction medium.

J. Järv, A. Kuznetsov, S. Salmar, 2013, Ultrasonics sonochemistry.

Significance of hydrophobic interactions in water–organic binary solvents

J. Järv, S. Salmar, T. Tenno, 2009 .

Mechanism and stoichiometry of 2,2-diphenyl-1-picrylhydrazyl radical scavenging by glutathione and its novel alpha-glutamyl derivative.

J. Järv, A. Kuznetsov, K. Kilk, 2009, Bioorganic chemistry.

Serine decomposition in solid-state catalytic isotope exchange of a peptide

J. Järv, U. Ragnarsson, D. Zaitsev, 1992 .

Mapping of ACE2 binding site on SARS-CoV-2 spike protein S1: docking study with peptides

J. Järv, A. Kuznetsov, 2020, Proceedings of the Estonian Academy of Sciences.

Kinetic analysis of inhibition of cAMP-dependent protein kinase catalytic subunit by the peptide-nucleoside conjugate AdcAhxArg6.

J. Järv, A. Kuznetsov, A. Uri, 2004, Bioorganic chemistry.

Stereochemical aspects of cholinesterase catalysis

J. Järv, 1984 .

Leaving group effects in butyrylcholinesterase reaction with organophosphorus inhibitors.

J. Järv, Ű. Langel, 1978, Biochimica et biophysica acta.

Neurotoxic agents interacting with the muscarinic acetylcholine receptor

J. Järv, 1994 .

Binding of specific ligands to muscarinic receptors alters the fluidity of membrane fragments from rat brain A fluorescence polarization study with lipid‐specific probes

J. Järv, J. Molotkovsky, L. Bergelson, 1988, FEBS letters.

Structure‐Activity Relationships in Acetylcholinesterase Reactions

J. Järv, T. Kesvatera, A. Aaviksaar, 1976 .

Novel systemically active galanin receptor 2 ligands in depression‐like behavior

J. Järv, T. Bártfai, I. Saar, 2013, Journal of neurochemistry.

ALEKSEI KUZNETSOV Allosteric effects in reactions catalyzed by the cAMP-dependent protein kinase catalytic subunit

J. Järv, 2009 .

Adenosine-5'-carboxylic acid peptidyl derivatives as inhibitors of protein kinases.

J. Järv, M. Loog, A. Uri, 1999, Bioorganic & medicinal chemistry letters.

Kinetics of N-methylscopolamine interaction with muscarinic receptor from rat cerebral cortex

J. Järv, M. Eller, 1989, Neurochemistry International.

Solvent-free synthesis of molecular bromine and its application for in situ bromination of aromatic compounds

J. Järv, I. Rahu, 2020, Proceedings of the Estonian Academy of Sciences.

Muscarinic Acetylcholine Receptors

J. Järv, T. Bártfai, 1988 .

Sonication effects on non-radical reactions. A sonochemistry beyond the cavitation?

J. Järv, S. Salmar, A. Tuulmets, 2014, Ultrasonics sonochemistry.

Kinetic sonication effects in aqueous acetonitrile solutions. Reaction rate levelling by ultrasound.

J. Järv, A. Kuznetsov, S. Salmar, 2013, Ultrasonics sonochemistry.

Sonication effects on ester hydrolysis in alcohol-water mixtures

J. Järv, S. Salmar, H. Hagu, 2007 .

Isomerization of the muscarinic receptor . antagonist complex.

J. Järv, T. Bártfai, B. Hedlund, 1979, The Journal of biological chemistry.

Kinetic aspects of l-quinuclidinyl benzilate interaction with muscarinic receptor

J. Järv, M. Eller, 1988, Neurochemistry International.

Computer modeling of the dynamic properties of the cAMP-dependent protein kinase catalytic subunit

Andrei Izvolski, Jaak Järv, Aleksei Kuznetsov, 2013, Comput. Biol. Chem..

Allosteric Cooperativity in Inhibition of Protein Kinase a Catalytic Subunit

J. Järv, A. Kuznetsov, 2008 .

QUANTUM CHEMICAL MODELLING OF THE EFFECT OF PROLINE RESIDUES ON PEPTIDE CONFORMATION

J. Järv, M. Karelson, K. Sak, 1998 .

Screening for the Optimal Specificity Profile of Protein Kinase C Using Electrospray Mass-Spectrometry

J. Järv, M. Loog, A. Närvänen, 2005, Journal of biomolecular screening.

Comparison of cAMP-dependent protein kinase substrate specificity in reaction with proteins and synthetic peptides.

J. Järv, M. Loog, N. Oskolkov, 2005, Biochimica et biophysica acta.

Adenosine triphosphate is full antagonist at human P2Y1 purinoceptors

J. Järv, K. Sak, 2000, Neuroscience Letters.

P2Y-receptor-ligand database.

A. Kreegipuu, J. Järv, K. Sak, 2000, TIBS -Trends in Biochemical Sciences. Regular ed.

Pyrimidinoceptor potentiation by ATP in NG108‐15 cells

J. Järv, M. Kelve, K. Sak, 1998, FEBS letters.

Kinetics of [35S]dATPαS interaction with P2Y1 purinoceptor in rat brain membranes

J. Järv, A. Oras, 2004, Neuroscience Letters.

Kinetic analysis of [35S]dATPαS interaction with P2y1 nucleotide receptor

J. Järv, E. Barnard, K. Kilk, 2002, Neurochemistry International.

Phosphate-substituted ATP analogs are antagonists at human P2Y1 purinoceptors.

J. Järv, K. Sak, G. Raidaru, 2000, Archives of biochemistry and biophysics.

Novel Galanin Receptor Subtype Specific Ligand in Depression Like Behavior

J. Järv, I. Saar, Ü. Langel, 2013, Neurochemical Research.

Differential Specificity of Protein Kinases A and C in Reaction with Synthetic Peptides

J. Järv, M. Loog, K. Sak, 1999 .

Oxyanion formation in phosphoryl transfer catalyzed by protein kinases A and C

J. Järv, 1996 .

Allosteric Effect of Adenosine Triphosphate on Peptide Recognition by 3′5′-Cyclic Adenosine Monophosphate Dependent Protein Kinase Catalytic Subunits

J. Järv, R. Kivi, Piret Arukuusk, 2016, The Protein Journal.

Ligand structure controlled allostery in cAMP-dependent protein kinase catalytic subunit

J. Järv, A. Kuznetsov, 2009, Central European Journal of Biology.

A model of non-exclusive binding of agonist and antagonist on G-protein coupled receptors.

J. Järv, 1995, Journal of theoretical biology.

An alternative model for bell-shaped concentration-response curves.

J. Järv, 1994, Trends in pharmacological sciences.

Modeling of the Amino Acid Side Chain Effects on Peptide Conformation

J. Järv, M. Karelson, K. Sak, 1999 .

Thermodynamic Aspects of cAMP Dependent Protein Kinase Catalytic Subunit Allostery

J. Järv, P. Jemth, R. Kivi, 2014, The Protein Journal.

In Vitro Ligand Binding Kinetics Explains the Pharmacokinetics of [18F]FE-PE2I in Dopamine Transporter PET Imaging.

J. Järv, J. Hiltunen, S. Kukk, 2018, ACS medicinal chemistry letters.

Production of biosensors with exchangeable enzyme-containing threads.

J. Järv, A. Rinken, T. Rinken, 2007, Analytical chemistry.

Dual Effect of Nucleotides on P2Y Receptors

J. Järv, E. Barnard, K. Sak, 2000, IUBMB life.

Dual effect of muscarinic receptor agonists on Ca2+ mobilization in SH-SY5Y neuroblastoma cells.

J. Järv, K. Åkerman, R. Hautala, 1995, European journal of pharmacology.

Dual effect of carbachol on the muscarinic receptor.

J. Järv, E. Karelson, T. Toomela, 1993, Biochemistry and molecular biology international.

A Novel Strategy of Effect-Directed Ligand Design for G-Protein Coupled Receptors

J. Järv, 1997 .

Strain criteria for alkenes: Two different manifestations

J. Järv, P. Burk, Ott Kekišev, 2020 .

Alkylboronic acids accelerate affinity labelling of acetylcholinesterase with N,N-dimethyl-2-phenylaziridinium ion.

J. Järv, P. Palumaa, 1984, Biochimica et biophysica acta.

NCAM-deficient mice show prominent abnormalities in serotonergic and BDNF systems in brain – Restoration by chronic amitriptyline

E. Castrén, J. Järv, T. Rantamäki, 2015, European Neuropsychopharmacology.

Calibration of glucose biosensors by using pre-steady state kinetic data.

J. Järv, T. Tenno, A. Rinken, 1998, Biosensors & bioelectronics.

Kinetics of Acrylodan-Labelled cAMP-Dependent Protein Kinase Catalytic Subunit Denaturation

J. Järv, P. Jemth, M. Loog, 2013, The Protein Journal.

Different States of Acrylodan-Labeled 3′5′-Cyclic Adenosine Monophosphate Dependent Protein Kinase Catalytic Subunits in Denaturant Solutions

J. Järv, R. Kivi, 2016, The Protein Journal.

Computational modeling of acrylodan-labeled cAMP dependent protein kinase catalytic subunit unfolding

Jaak Järv, Aleksei Kuznetsov, Rait Kivi, 2016, Comput. Biol. Chem..

Influence of steric effects in solid-phase aza-peptide synthesis

J. Järv, Meeli Arujõe, A. Ploom, 2018 .

Computational simulation of ligand docking to L-type pyruvate kinase subunit

Jaak Järv, Aleksei Kuznetsov, Ilona Faustova, 2014, Comput. Biol. Chem..

Influence of pH on butylylcholinesterase reaction with organophosphorus inhibitors.

J. Järv, Ű. Langel, 1978, Biochimica et biophysica acta.

Alcoholysis of Primary Amides in the Presence of CF3SO3H

J. Järv, A. Konist, A. Mastitski, 2023, Organic Preparations and Procedures International.

Structure-reactivity relationships in organosilicon chemistry revisited

J. Järv, A. Tuulmets, A. Ploom, 2011 .

Kinetic evidence for different mechanisms of interaction of black mamba toxins MT alpha and MT beta with muscarinic receptors.

J. Järv, K. Åkerman, E. Karlsson, 2001, Toxicon.

Synthesis of 3H-labeled N-(3-iodoprop-2E-enyl)-2beta-carbomethoxy-3beta-(4-methylphenyl)nortropane (PE2I) and its interaction with mice striatal membrane fragments.

J. Järv, C. Halldin, V. Stepanov, 2007, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Kinetic evidence for isomerization of the dopamine receptor-raclopride complex

K. Fuxe, J. Järv, A. Rinken, 1996, Neurochemistry International.

Probing l-Pyruvate Kinase Regulatory Phosphorylation Site by Mutagenesis

J. Järv, I. Faustova, M. Loog, 2012, The Protein Journal.

Phosphorylation is switch of L-type pyruvate kinase allostery

J. Järv, A. Kuznetsov, I. Faustova, 2010, Central European Journal of Biology.

ACE2 Peptide Fragment Interaction with Different S1 Protein Sites

J. Järv, A. Kuznetsov, Ü. Langel, 2021, International Journal of Peptide Research and Therapeutics.

Dual Effect of Nucleotides on P2Y Receptors

J. Järv, E. Barnard, K. Sak, 2000, IUBMB life.

Substrate specificity studies on protein kinase C

J. Järv, P. Ekman, L. Engström, 1993 .