C. Epstein

C. Epstein, F. Sharp, J. Honkaniemi, 1997, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Increased Superoxide Dismutase Activity Improves Survival of Cultured Postnatal Midbrain Neurons

C. Epstein, D. Sulzer, S. Przedborski, 1996, Journal of neurochemistry.

STUDIES ON LACTATE DEHYDROGENASE ISOZYMES IN GAMETES AND EARLY DEVELOPMENT OF MICE

C. Epstein, R. Erickson, H. Spielmann, 1975 .

Mycoplasma Contamination of Cultured Amniotic Fluid Cells: Potential Hazard to Prenatal Chromosomal Diagnosis

C. Epstein, E. Stanbridge, E. Schneider, 1974, Science.

Mitochondrial disease in superoxide dismutase 2 mutant mice.

C. Epstein, S. Melov, D. Wallace, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Prenatal diagnosis of genetic diseases.

C. Epstein, M. Golbus, 1977, American scientist.

Ichthyosis and neutral lipid storage disease.

J. J. O'Donnell, C. Epstein, L. Epstein, 1985, American journal of medical genetics.

Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype.

C. Epstein, G. Martin, C. Sprague, 1970, Laboratory investigation; a journal of technical methods and pathology.

Nephrogenic diabetes insipidus in mice lacking aquaporin-3 water channels.

C J Epstein, A S Verkman, C. Epstein, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Defective Secretion of Saliva in Transgenic Mice Lacking Aquaporin-5 Water Channels*

C. Epstein, A. Verkman, E. Carlson, 1999, The Journal of Biological Chemistry.

Viral transformation of rat myoblasts: effects on fusion and surface properties.

C. Epstein, R. Hynes, Gage Martin, 1976, Developmental biology.

Multiple congenital anomalies in a fetus exposed to 5-fluorouracil during the first trimester.

C. Epstein, M. Golbus, T. Miller, 1980, American journal of obstetrics and gynecology.

Pleiotropic effects of the mouse lethal yellow (Ay) mutation explained by deletion of a maternally expressed gene and the simultaneous production of agouti fusion RNAs.

G. Barsh, C. Epstein, M. Miller, 1994, Development.

CHARACTERIZATION OF THE ACTIVE PRODUCT OBTAINED BY OXIDATION OF REDUCED LYSOZYME.

C. Epstein, R. Goldberger, 1963, The Journal of biological chemistry.

Mitochondrial Malate Dehydrogenase: Reversible Denaturation Studies

A. Schechter, C. Epstein, 1968, Science.

Cell size, nuclear content, and the development of polyploidy in the Mammalian liver.

C. Epstein, Charles J. Epstein, 1967, Proceedings of the National Academy of Sciences of the United States of America.

Oligosyndactyly: A lethal mutation in the mouse that results in mitotic arrest very early in development

C. Epstein, T. Magnuson, 1984, Cell.

Primary afferent tachykinins are required to experience moderate to intense pain

C. Epstein, A. Basbaum, P. Mantyh, 1998, Nature.

Werner's syndrome; caricature of aging. A genetic model for the study of degenerative diseases.

C. Epstein, A. Motulsky, G. Martin, 1965, Transactions of the Association of American Physicians.

Manipulation of myogenesis in vitro: Reversible inhibition by DMSO

H. Blau, C. Epstein, 1979, Cell.

X–chromosome inactivation during differentiation of female teratocarcinoma stem cells in vitro

C. Epstein, B. Travis, Sara B. Cohen, 1978, Nature.

A Y-autosome translocation 46,X,t(Yq-7q+) associated with multiple congenital anomalies.

C. Epstein, F. Conte, A. J. Develing, 1973, The Journal of pediatrics.

Detection of mycoplasma contamination in cultured human fibroblasts. Comparison of biochemical and microbiological techniques.

C. Epstein, E. Schneider, W. Epstein, 1973, Experimental cell research.

Comparative Gene Mapping of Human Chromosome 21 and Mouse Chromosome 16 a

D. Cox, C. Epstein, 1985, Annals of the New York Academy of Sciences.

Werner's syndrome and aging: a reappraisal.

C. Epstein, 1985, Advances in experimental medicine and biology.

The production of antibodies against mammalian LDH-1.

C. Epstein, R. Erickson, H. Spielman, 1974, Analytical biochemistry.

Effect of 5-bromodeoxyuridine on pre-implantation mouse embryo development.

C. Epstein, M. Golbus, 1974, Differentiation; research in biological diversity.

Use of teratocarcinoma stem cells as a model system for the study of X-chromosome inactivation in vitro.

C. Epstein, D. Martin, G. Martin, 1978, Basic life sciences.

Synthesis of LDH-1 during mamalian oogenesis and early development.

C. Epstein, R. Erickson, F. Mangia, 1976, Developmental biology.

Biochemical studies of growing mouse oocytes: preparation of oocytes and analysis of glucose-6-phosphate dehydrogenase and lactate dehydrogenase activities.

C. Epstein, F. Mangia, 1975, Developmental biology.

Protein synthetic patterns in teratocarcinoma stem cells and mouse embryos at early stages of development.

C. Epstein, G. Martin, S. Smith, 1978, Developmental biology.

Expression of the Mammalian X Chromosome before and after Fertilization

C. Epstein, 1972, Science.

The Antiproliferative Effects of Interferon on Murine Embryonic Cells

C. Epstein, L. Epstein, K. Drasner, 1979, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Isolation of a mouse homolog of the human DAZ (Deleted in Azoospermia) gene

C. Epstein, R. Maiwald, R. Luche, 1996, Mammalian Genome.

Overexpression of manganese superoxide dismutase (MnSOD) in whole lung or alveolar type II cells of MnSOD transgenic mice does not provide intrinsic lung irradiation protection

C. Epstein, J. Whitsett, J. Greenberger, 2001, International journal of cancer.

Acceleration of reactivation of reduced bovine pancreatic ribonuclease by a microsomal system from rat liver.

C. Epstein, C. Anfinsen, R. Goldberger, 1963, The Journal of biological chemistry.

Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4.

C. Epstein, A. Verkman, Baoxue Yang, 1997, The Journal of clinical investigation.

The overexpression of major antioxidant enzymes does not extend the lifespan of mice

C. Epstein, J. Vijg, A. Bokov, 2008, Aging cell.

Genetic modifiers of the phenotype of mice deficient in mitochondrial superoxide dismutase.

C. Epstein, M. Naeemuddin, Ting-Ting Huang, 2006, Human molecular genetics.

The challenge of Down syndrome.

C. Epstein, S. Antonarakis, 2006, Trends in molecular medicine.

The genetics of the skeleton

C. Epstein, 1987 .

MYH9 spectrum of autosomal‐dominant giant platelet syndromes: Unexpected association with fibulin‐1 variant‐D inactivation

C. Epstein, J. Martignetti, N. Amariglio, 2003, American journal of hematology.

App Gene Dosage Modulates Endosomal Abnormalities of Alzheimer's Disease in a Segmental Trisomy 16 Mouse Model of Down Syndrome

C. Epstein, M. Staufenbiel, R. Nixon, 2003, The Journal of Neuroscience.

Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome.

D. Holtzman, D. Holtzman, C. Epstein, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Skeletal defects in paternal uniparental disomy for chromosome 14 are re-capitulated in the mouse model (paternal uniparental disomy 12)

L. Shaffer, C. Epstein, V. Sutton, 2003, Human Genetics.

Response to Dr. Shapiro by Dr. Epstein

C. Epstein, 1989 .

Manganese Superoxide Dismutase Mediates the Early Release of Mitochondrial Cytochrome C and Subsequent DNA Fragmentation after Permanent Focal Cerebral Ischemia in Mice

C J Epstein, C. Epstein, M. Fujimura, 1999, The Journal of Neuroscience.

Human Copper‐Zinc Superoxide Dismutase Transgenic Mice Are Highly Resistant to Reperfusion Injury After Focal Cerebral Ischemia

Jun Chen, Guoyuan Yang, Charles J. Epstein, 1994, Stroke.

In utero diagnosis of globoid cell leukodystrophy (Krabb's disease).

C. Epstein, E. Schneider, K. Suzuki, 1971, Biochemical and biophysical research communications.

DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome.

Xavier Estivill, Dean Nizetic, Gareth Denyer, 2008, American journal of human genetics.

Uniparental isodisomy for paternal 7p and maternal 7q in a child with growth retardation.

C. Epstein, F. Chehab, M. Norton, 1994, American journal of human genetics.

Identification and characterization of a new Down syndrome model, Ts[Rb(12.1716)]2Cje, resulting from a spontaneous Robertsonian fusion between T(1716)65Dn and mouseChromosome 12

C. Epstein, W. Mobley, P. Belichenko, 2005, Mammalian Genome.

Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities.

C. Epstein, E. Rubin, W. Mobley, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Partial trisomy for the distal long arm of chromosome 5 (region q34→qter). A new clinically recognizable syndrome

C. Epstein, U. Francke, C. Curry, 1979 .

The long-range restriction map surrounding the mouse agouti locus reveals a disparity between physical and genetic distances.

G. Barsh, C. Epstein, 1989, Genomics.

Deletion of chromosome 21 and normal intelligence: molecular definition of the lesion

D. Cox, S. Pulst, C. Epstein, 1991, Human Genetics.

Enlarged brain ventricles and impaired neurogenesis in the Ts1Cje and Ts2Cje mouse models of Down syndrome.

K. Yamakawa, C. Epstein, Eiichi Takaki, 2010, Cerebral cortex.

Inborn errors of development : the molecular basis of clinical disorders of morphogenesis

C. Epstein, A. Wynshaw-Boris, R. Erickson, 2016 .

Autosomal-dominant giant platelet syndromes: a hint of the same genetic defect as in Fechtner syndrome owing to a similar genetic linkage to chromosome 22q11-13.

C. Epstein, N. Amariglio, G. Rechavi, 2000, Blood.

Genetic modification of prenatal lethality and dilated cardiomyopathy in Mn superoxide dismutase mutant mice.

C. Epstein, P. Ursell, E. Carlson, 2001, Free radical biology & medicine.

Overexpression of Mn superoxide dismutase does not increase life span in mice.

C. Epstein, Wook Song, A. Salmon, 2009, The journals of gerontology. Series A, Biological sciences and medical sciences.

Strain-dependent high-level expression of a transgene for manganese superoxide dismutase is associated with growth retardation and decreased fertility.

C. Epstein, E. Carlson, T. Oberley, 2001, Free radical biology & medicine.

Enhanced susceptibility of mouse embryos heterozygous for oligosyndactyly (Os/+) to mitomycin C-induced skeletal abnormalities.

C. Epstein, P. A. Moreno, 1987, Teratology.

Electrophoretic analysis of proteins synthesized by preimplantation mouse embryos.

C. Epstein, S. Smith, 1974, Developmental biology.

Production of viable adult trisomy 17 reversible diploid mouse chimeras.

D. Cox, C. Epstein, T. Magnuson, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Production of viable adult trisomy 17 *-* diploid mouse chimeras

D. Cox, C. Epstein, T. Magnuson, 2022 .

Cardiomyopathy in mice with paternal uniparental disomy for chromosome 12

C. Epstein, P. Ursell, E. Carlson, 2001, Genesis.

The Effects of Chromosomal Aneuploidy on Early Development Experimental Approaches

C. Epstein, 1981 .

From Down Syndrome to the Human in Human Genetics * * Previously presented at the annual meeting

C. Epstein, 2002 .

2001 William Allan Award Address. From Down syndrome to the "human" in "human genetics".

C. Epstein, 2002, American journal of human genetics.

The early lethality of autosomal monosomy in the mouse.

C. Epstein, T. Magnuson, S. Debrot, 1985, The Journal of experimental zoology.

Mouse monosomies and trisomies as experimental systems for studying mammalian aneuploidy

C. Epstein, 1985 .

CHAPTER 24 – Early Embryonic Development: Normal and Abnormal

C. Epstein, 1984 .

Production and properties of mouse trisomy 15↔diploid chimeras

D. Cox, C. Epstein, Sandra A. Smith, 1983 .

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

C. Epstein, L. Noble, S. Melov, 1995, Nature Genetics.

Altered levels of glucose-6-phosphate dehydrogenase stabilizing factors in X-linked chronic granulomatous disease.

C. Epstein, D. Stites, R. Erickson, 1972, The Journal of laboratory and clinical medicine.

Partial deficiency of manganese superoxide dismutase exacerbates a transgenic mouse model of amyotrophic lateral sclerosis

O. Andreassen, C. Epstein, R. Ferrante, 2000, Annals of neurology.

Ubiquitous overexpression of CuZn superoxide dismutase does not extend life span in mice.

C J Epstein, C. Epstein, E. Carlson, 2000, The journals of gerontology. Series A, Biological sciences and medical sciences.

Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity.

Yan Li, Arlan Richardson, Alex Bokov, 2009, The journals of gerontology. Series A, Biological sciences and medical sciences.

Use of Concanavalin A to Monitor Changes in Glycoprotein Synthesis during Early Mouse Development

C. Epstein, T. Magnuson, 1981 .

Handling of actinomycin D by preimplantation mouse embryos.

C. Epstein, S. Smith, 1978, Experimental cell research.

The genetic activity of early mammalian embryos.

C. Epstein, 1976, Current topics in pathology. Ergebnisse der Pathologie.

Amino acid uptake and protein synthesis in preimplantation mouse embryos

C. Epstein, Sandra A. Smith, 1973 .

Precursor pools and RNA synthesis in preimplantation mouse embryos.

C. Epstein, D. Daentl, 1971, Developmental biology.

Developmental interrelationships of uridine uptake. Nucleotide formation and incorporation into RNA by early mammalian embryos.

C. Epstein, D. Daentl, 1971, Developmental biology.

Phosphoribosyltransferase activity during early mammalian development.

C. Epstein, 1970, The Journal of biological chemistry.

Mammalian Oocytes: X Chromosome Activity

C. Epstein, 1969, Science.

Synaptic and cognitive abnormalities in mouse models of down syndrome: Exploring genotype‐phenotype relationships

C. Epstein, W. Mobley, P. Belichenko, 2007, The Journal of comparative neurology.

Down syndrome: toward a molecular definition of the phenotype.

C J Epstein, S. Pulst, C. Epstein, 2005, American journal of medical genetics. Supplement.

Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress.

C. Epstein, G. Freeman, Hong Yang, 2004, Free radical biology & medicine.

Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging.

C. Epstein, M. Pahlavani, Ting-Ting Huang, 2003, Physiological genomics.

Intrauterine diagnosis of genetic defects: results, problems, and follow-up of one hundred cases in a prenatal genetic detection center.

C. Epstein, E. Schneider, M. Golbus, 1974, American journal of obstetrics and gynecology.

Central nervous system expression of HIV-1 Gp120 activates the hypothalamic-pituitary-adrenal axis: evidence for involvement of NMDA receptors and nitric oxide synthase.

F. Bloom, L. Mucke, C. Epstein, 1996, Virology.

Hippocampal Long-Term Potentiation Suppressed by Increased Inhibition in the Ts65Dn Mouse, a Genetic Model of Down Syndrome

R. Malenka, C. Epstein, W. Mobley, 2004, The Journal of Neuroscience.

The consequences of chromosome imbalance.

C J Epstein, C. Epstein, Charles J. Epstein, 2005, American journal of medical genetics. Supplement.

Chance vs. causality in the association of Down syndrome and holoprosencephaly.

C. Epstein, M. Golabi, S. Seto, 1988, American journal of medical genetics.

Specificity versus nonspecificity in the pathogenesis of aneuploid phenotypes.

C. Epstein, 1988, American journal of medical genetics.

Protocols to establish genotype-phenotype correlations in Down syndrome.

E. Courchesne, C. Epstein, J. Korenberg, 1991, American journal of human genetics.

Stem cell deficiencies and thymic abnormalities in fetal mouse trisomy 16

D. Cox, C. Epstein, R. Philip, 1985, The Journal of experimental medicine.

Mouse Trisomy 16: An Animal Model of Human Trisomy 21 (Down Syndrome) a

D. Cox, C. Epstein, L. Epstein, 1985, Annals of the New York Academy of Sciences.

Mouse Models of Human Trisomy 21 (Down Syndrome)

C. Epstein, Ting-Ting Huang, C. Berger, 1992 .

The source of lactate dehydrogenase in preimplantation mouse embryos

C. Epstein, Sandra A. Smith, L. Kwok, 1971, FEBS letters.

Both X chromosomes function before visible X-chromosome inactivation in female mouse embryos

C. Epstein, B. Travis, Sandra A. Smith, 1978, Nature.

Altered surfactant homeostasis and alveolar type II cell morphology in mice lacking surfactant protein D.

C. Epstein, J. Goerke, E. Carlson, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Biochemical development of preimplantation mouse embryos: In vivo activities of fructose 1,6-diphosphate aldolase, glucose 6-phosphate dehydrogenase, malate dehydrogenase, and lactate dehydrogenase

C. Epstein, C. W. Smith, E. Wegienka, 1969, Biochemical Genetics.

X chromosome expression during oogenesis in the mouse.

C. Epstein, F. Mangia, G. Abbo-Halbasch, 1975, Developmental biology.

The Molecular Biology of Down Syndrome

C. Epstein, E. Carlson, P. H. Chan, 1990 .

WERNER'S SYNDROME.

C. Epstein, 1965, Annals of internal medicine.

STRUCTURAL AND CONTROL GENE DEFECTS IN HEREDITARY DISEASES IN MAN.

C. Epstein, 1964, Lancet.

Genes contributing to prion pathogenesis.

Richard C. Moore, F. Cohen, L. Mucke, 2008, The Journal of general virology.

AN APPROACH TO THE PROBLEM OF CONFORMATIONAL ISOZYMES

A. Schechter, C. Epstein, 1968, Annals of the New York Academy of Sciences.

Increased App Expression in a Mouse Model of Down's Syndrome Disrupts NGF Transport and Causes Cholinergic Neuron Degeneration

Ahmad Salehi, Ralph A. Nixon, Weiming Xia, 2006, Neuron.

H-2 antigens as genetic markers: A two-dimensional gel electrophoretic study

C. Epstein, J. Sawicki, 2005, Immunogenetics.

Down Syndrome, Molecular Genetics of

C. Epstein, 2006 .

The Role of Oxidative Imbalance in the Pathogenesis of Down Syndrome

C. Epstein, Ting-Ting Huang, S. Mantha, 2003 .

Nerve growth factor reverses neuronal atrophy in a Down syndrome model of age‐related neurodegeneration

D. Holtzman, F. Gage, C. Epstein, 1993, Neurology.

Developing a national collaborative study system for rare genetic diseases

C. Epstein, B. Korf, M. Watson, 2008, Genetics in Medicine.

REVERSIBLE DENATURATION OF RABBIT-MUSCLE LACTATE DEHYDROGENASE.

C. Epstein, R. Goldberger, M. Carter, 1964, Biochimica et biophysica acta.

The Hunter syndrome in females: is there an autosomal recessive form of iduronate sulfatase deficiency?

B. Migeon, C. Epstein, I. Liebaers, 1977, American journal of human genetics.

The new dysmorphology: application of insights from basic developmental biology to the understanding of human birth defects.

C. Epstein, 1995, Proceedings of the National Academy of Sciences of the United States of America.

GENETIC COUNSELLING FOR HUNTER SYNDROME

C. Epstein, I. Liebaers, E. Neufeld, 1976, The Lancet.

Physical and genetic characterization of a 75-kilobase deletion associated with al, a recessive lethal allele at the mouse agouti locus.

G. Barsh, C. Epstein, 1989, Genetics.

Manganese Superoxide Dismutase Signals Matrix Metalloproteinase Expression via H2O2-dependent ERK1/2 Activation*

C. Epstein, J. Rutter, C. Brinckerhoff, 2001, The Journal of Biological Chemistry.

Dosage-dependent over-expression of genes in the trisomic region of Ts1Cje mouse model for Down syndrome.

K. Yamakawa, C. Epstein, N. Nukina, 2004, Human molecular genetics.

Increased Oxidative Damage Is Correlated to Altered Mitochondrial Function in Heterozygous Manganese Superoxide Dismutase Knockout Mice*

C. Epstein, H. Van Remmen, C. C. Conrad, 1998, The Journal of Biological Chemistry.

Expression of c-fos and hsp70 mRNA after traumatic brain injury in transgenic mice overexpressing CuZn-superoxide dismutase.

C. Epstein, F. Sharp, H. Kinouchi, 1995, Brain research. Molecular brain research.

Mild and severe Hunter syndrome (MPS II) within the same sibships

C. Epstein, R. Erickson, S. Yatziv, 1977, Clinical genetics.

Transgenic mice overexpressing human copper/zinc-superoxide dismutase (Cu/Zn SOD) are not resistant to endotoxic shock.

S. de Vos, C. Epstein, H. Koeffler, 1995, Biochemical and biophysical research communications.

The in vivo gene expression signature of oxidative stress.

C. Epstein, F. Muller, H. Remmen, 2008, Physiological genomics.

Down's syndrome: Critical genes in a critical region

Charles J. Epstein, C. Epstein, 2006, Nature.

Craniofacial phenotypes in segmentally trisomic mouse models for Down syndrome.

Joan T Richtsmeier, Ann Zumwalt, J. Richtsmeier, 2002, American journal of medical genetics.

Autoradiographic evidence for methamphetamine-induced striatal dopaminergic loss in mouse brain: attenuation in CuZn-superoxide dismutase transgenic mice

C. Epstein, J. Cadet, H. Hirata, 1996, Brain Research.

Hereditary adrenocortical unresponsiveness to adrenocorticotropic hormone.

C. Epstein, G. Daniels, M. Grumbach, 1972, The Journal of pediatrics.

Nuclear Ploidy in Mammalian Parenchymal Liver Cells

C. Epstein, EUGENIE A. GATENS, Eugenie A. Gatens, 1967, Nature.

Genetic Dissection of Region Associated with Behavioral Abnormalities in Mouse Models for Down Syndrome

C. Epstein, E. Rubin, Desmond J. Smith, 2000, Pediatric Research.

Increased lipid peroxidation in Down’s syndrome mouse models

K. Yamakawa, C. Epstein, Eiichi Takaki, 2009, Journal of neurochemistry.

Prolonged ethanol administration depletes mitochondrial DNA in MnSOD-overexpressing transgenic mice, but not in their wild type littermates.

C. Epstein, D. Pessayre, B. Fromenty, 2009, Toxicology and applied pharmacology.

Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging

C. Epstein, F. Muller, H. Remmen, 2006, Mechanisms of Ageing and Development.

Synaptic structural abnormalities in the Ts65Dn mouse model of down syndrome

C. Epstein, E. Masliah, W. Mobley, 2004, The Journal of comparative neurology.

Increased synaptic depression in the Ts65Dn mouse, a model for mental retardation in Down syndrome

C. Epstein, S. Rapoport, E. Carlson, 1999, Neuropharmacology.

Overexpression of mSim2 gene in the zona limitans of the diencephalon of segmental trisomy 16 Ts1Cje fetuses, a mouse model for trisomy 21: a novel whole-mount based RNA hybridization study.

C. Epstein, F. Vialard, E. Carlson, 2000, Brain research. Developmental brain research.

Mouse model of neurodegeneration: atrophy of basal forebrain cholinergic neurons in trisomy 16 transplants.

D. Holtzman, F. Gage, C. Epstein, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Aneuploidy in Mouse and Man

C. Epstein, 1987 .

Gene dosage effect for glycinamide ribonucleotide synthetase in human fibroblasts trisomic for chromosome 21.

C. Epstein, J. Bartley, 1980, Biochemical and biophysical research communications.

Fetal globoid cell leukocystrophy (Krabbe disease). Pathological and biochemical examination.

C. Epstein, E. Schneider, W. Ellis, 1973, Archives of neurology.

Inefficacy of fresh frozen plasma therapy of mucopolysaccharidosis II.

C. Epstein, R. Erickson, W. V. Robertson, 1972, Pediatrics.

Molecular genetics of chromosome 21 and Down syndrome : proceedings of the Sixth Annual National Down Syndrome Society Symposium, held in New York, New York, December 7-8, 1989

C. Epstein, D. Patterson, 1990 .

Models for Down syndrome: chromosome 21-specific genes in mice.

C. Epstein, E. Carlson, C. Berger, 1990, Progress in clinical and biological research.

Hunter syndrome presenting as macrocephaly and hydrocephalus.

C. Epstein, S. Yatziv, 1977, Journal of medical genetics.

Lack of relationship between blood and urine levels of glycosaminoglycans and lysomal enzymes.

C. Epstein, R. Erickson, R. Sandman, 1975, Biochemical medicine.

Deletion of 7q11.23 Genes and Williams Syndrome

A. Galaburda, U. Bellugi, C. Epstein, 2008 .

Transgenic mice and knockout mutants in the study of oxidative stress in brain injury.

C. Epstein, P. Chan, H. Kinouchi, 1995, Journal of neurotrauma.

Abnormal synaptic plasticity in the Ts1Cje segmental trisomy 16 mouse model of Down syndrome

C. Epstein, Z. Galdzicki, R. Siarey, 2005, Neuropharmacology.

THE REOXIDATION OF REDUCED RIBONUCLEASE DERIVATIVES.

C. Epstein, R. Goldberger, 1964, The Journal of biological chemistry.

The human trisomy 21 brain: Insights from mouse models of Down syndrome

D. Holtzman, C. Epstein, W. Mobley, 1996 .

Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase.

C. Epstein, P. Chan, H. Kinouchi, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Genetics in primary care: what do we expect?

C. Epstein, 2001, Nature Genetics.

Regional alteration of cholinergic function in central neurons of trisomy 16 mouse fetuses, an animal model of human trisomy 21 (Down syndrome)

C. Epstein, S. Rapoport, J. Fiedler, 1994, Brain Research.

Abnormalities in the interferon response and immune systems in Down syndrome: studies in human trisomy 21 and mouse trisomy 16.

C. Epstein, L. Epstein, J. Weil, 1987, Progress in clinical and biological research.

Brain Injury after Perinatal Hypoxia-Ischemia Is Exacerbated in Copper/Zinc Superoxide Dismutase Transgenic Mice

C. Epstein, D. Ferriero, R. Sheldon, 1996, Pediatric Research.

Familial acrocephalosyndactyly (Pfeiffer syndrome).

C. Epstein, H. Steinbach, R. Saldino, 1972, The American journal of roentgenology, radium therapy, and nuclear medicine.

Reactive Oxygen Species and Vascular Cell Adhesion Molecule-1 in Distant Organ Failure Following Bile Duct Obstruction in Mice

C. Epstein, D. Granger, M. Kitajima, 2002, Digestive Diseases and Sciences.

Genomic imprinting: normal complementation of murine chromosome 16.

C. Epstein, C. Berger, 1989, Genetical research.

Prenatal detection of genetic disorders.

C. Epstein, E. Schneider, S. Friedman, 1972, American journal of human genetics.

Is modern genetics the new eugenics?

C. Epstein, 2003, Genetics in Medicine.

Medical genetics in the genomic medicine of the 21st century.

C. Epstein, Charles J Epstein, 2006, American journal of human genetics.

Overexpressing Cu/Zn superoxide dismutase enhances survival of transplanted neurons in a rat model of Parkinson's disease

Charles J. Epstein, Patrik Brundin, C. Epstein, 1995, Nature Medicine.

The Properties of Poly-dl-alanyl Trypsin and Poly-dl-alanyl Chymotrypsin

C. Epstein, C. Anfinsen, M. Sela, 1962 .

Brain infarction is not reduced in SOD-1 transgenic mice after a permanent focal cerebral ischemia.

C. Epstein, P. Chan, E. Carlson, 1993, Neuroreport.

A unique set of polypeptides is induced by gamma interferon in addition to those induced in common with alpha and beta interferons.

C. Epstein, J. Sedmak, L. Epstein, 1983, Nature.

Slit1 and Slit2 Cooperate to Prevent Premature Midline Crossing of Retinal Axons in the Mouse Visual System

Carol A. Mason, Marc Tessier-Lavigne, Charles J. Epstein, 2002, Neuron.

SOD‐1 Transgenic Mice as a Model for Studies of Neuroprotection in Stroke and Brain Trauma a

C. Epstein, H. Kinouchi, E. Carlson, 1994, Annals of the New York Academy of Sciences.

Transgenic and mutant mice for oxygen free radical studies.

C. Epstein, Ting-Ting Huang, I. Raineri, 2002, Methods in enzymology.

Transgenic copper/zinc-superoxide dismutase ameliorates caerulein-induced pancreatitis in mice.

C. Epstein, A. Satoh, T. Shimosegawa, 1997, Biochemical and biophysical research communications.

Transgenic copper/zinc superoxide dismutase modulates susceptibility totypeIdiabetes H.MICHAELKUBISCH*t, JUNQIAN WANGt,RALFLUCHE§, ELAINECARLSON§, TAMMYM.BRAYI,

C. Epstein, J. Phillips, 1994 .

CuZn-superoxide dismutase (CuZnSOD) transgenic mice show resistance to the lethal effects of methylenedioxyamphetamine (MDA) and of methylenedioxymethamphetamine (MDMA)

C. Epstein, J. Cadet, E. Carlson, 1994, Brain Research.

Expression of hsp 70 mRNA is induced in the brain of transgenic mice overexpressing human CuZn-superoxide dismutase following transient global cerebral ischemia

C. Epstein, F. Sharp, P. Chan, 1996, Brain Research.

Sex chromosome expression in embryonic development.

C. Epstein, 1983, Differentiation; research in biological diversity.

A new familial arthrogryposis without weakness

C. Epstein, R. Layzer, B. Berg, 1974, Neurology.

Attenuation of acute and chronic damage following traumatic brain injury in copper, zinc-superoxide dismutase transgenic mice.

C. Epstein, G. Gobbel, P. Chan, 1996, Journal of neurosurgery.

The reversible reduction of disulfide bonds in trypsin and ribonuclease coupled to carboxymethyl cellulose.

C. Epstein, C. Anfinsen, C B ANFINSEN, 1962, The Journal of biological chemistry.

Partial trisomy for the distal long arm of chromosome 5 (region q34 leads to qter). A new clinically recognizable syndrome.

C. Epstein, U. Francke, C. Curry, 1979, Clinical Genetics.

Autoradiographic distribution of Mu opioid receptors in the brains of Cu/Zn‐superoxide dismutase mice

C. Epstein, J. Cadet, K. Kujirai, 1994, Synapse.

Prolonged Expression of hsp70 mRNA following Transient Focal Cerebral Ischemia in Transgenic Mice Overexpressing CuZn-Superoxide Dismutase

C. Epstein, F. Sharp, J. Koistinaho, 1994, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Autoradiographic distribution of [3H]neurotensin receptors in the brains of superoxide dismutase transgenic mice

Kayoko Kujirai, C. Epstein, J. Cadet, 1993, Synapse.

Aneuploidy and morphogenesis.

C. Epstein, 1991, Progress in clinical and biological research.

Effects of Nitric Oxide Synthase Inhibition on Brain Infarction in SOD-1-Transgenic Mice following Transient Focal Cerebral Ischemia

C. Epstein, P. Chan, H. Kinouchi, 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Failed retrograde transport of NGF in a mouse model of Down's syndrome: Reversal of cholinergic neurodegenerative phenotypes following NGF infusion

Ahmad Salehi, Jonathan D. Cooper, Charles J. Epstein, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Effect of SOD1 overexpression on age- and noise-related hearing loss.

C. Epstein, A. Lalwani, Ting-Ting Huang, 2003, Free radical biology & medicine.

Spectral studies on the denaturation of myoglobin.

A. Schechter, C. Epstein, 1968, Journal of molecular biology.

The center-satellite system for the wide-scale distribution of genetic counseling services.

C. Epstein, R. Erickson, M. Golbus, 1975, American journal of human genetics.

Electrophysiological properties of cultured dorsal root ganglion and spinal cord neurons of normal and trisomy 16 fetal mice.

C. Epstein, S. Rapoport, S. Smith, 1987, Brain research.

Tetrasomy 16 in the mouse: a more severe condition than the corresponding trisomy.

C. Epstein, S. Debrot, 1986, Journal of embryology and experimental morphology.

Mice with a Partial Deficiency of Manganese Superoxide Dismutase Show Increased Vulnerability to the Mitochondrial Toxins Malonate, 3-Nitropropionic Acid, and MPTP

Ole A. Andreassen, Elaine J. Carlson, Charles J. Epstein, 2001, Experimental Neurology.

Decreased Pulmonary Radiation Resistance of Manganese Superoxide Dismutase (MnSOD)-Deficient Mice is Corrected by Human Manganese Superoxide Dismutase-Plasmid/Liposome (SOD2-PL) Intratracheal Gene Therapy

C. Epstein, J. Greenberger, M. Epperly, 2000, Radiation research.

Genetic modification of the dilated cardiomyopathy and neonatal lethality phenotype of mice lacking manganese superoxide dismutase

C. Epstein, Ting-Ting Huang, E. Carlson, 1998, AGE.

Transgenic Murine Dopaminergic Neurons Expressing Human Cu/Zn Superoxide Dismutase Exhibit Increased Density in Culture, but No Resistance to Methylphenylpyridinium‐Induced Degeneration

C J Epstein, C. Epstein, J. Sanchez-Ramos, 1997, Journal of neurochemistry.

Expression of c-fos mRNA after a mild focal cerebral ischemia in SOD-1 transgenic mice

C. Epstein, F. Sharp, S. Sagar, 1994, Brain Research.

Expression of hsp70 mRNA is induced in the brain of transgenic mice overexpressing human CuZn-superoxide dismutase following transient global cerebral ischemia.

C. Epstein, F. Sharp, P. Chan, 1996, Brain research.

Chapter 9. The Use of Growth Factors to Stimulate the Proliferation of Amniotic Fluid Cells

C. Epstein, 1982 .

Stimulation of amniotic fluid cell growth by cartilage growth factor.

C. Epstein, M. Klagsbrun, M. Djalali, 1980, American journal of medical genetics.

Role of Superoxide Dismutase in Ischemic Brain Injury: A Study Using SOD-1 Transgenic Mice

C. Epstein, P. Chan, H. Kinouchi, 1998, Cellular and Molecular Neurobiology.

The cerebellar transcriptome during postnatal development of the Ts1Cje mouse, a segmental trisomy model for Down syndrome.

L. Personnaz, J. Rossier, C. Epstein, 2005, Human molecular genetics.

INVOLVEMENT OF OXIDATIVE AND L‐ARGININE‐NO PATHWAYS IN THE NEUROTOXICITY OF DRUGS OF ABUSE IN VITRO

C. Epstein, B. Ladenheim, C. Cerruti, 1995, Clinical and Experimental Pharmacology and Physiology.

The mouse lethal nonagouti (a(x)) mutation deletes the S‐adenosylhomocysteine hydrolase (Ahcy) gene.

G. Barsh, C. Epstein, F. Arredondo-Vega, 1994, The EMBO journal.

Preliminary characterization of the central nervous system in partial trisomy 16 mice.

D. Holtzman, C. Epstein, W. Mobley, 1995, Progress in clinical and biological research.

Epilogue: toward the twenty-first century with Down syndrome--a personal view of how far we have come and of how far we can reasonably expect to go.

C. Epstein, 1995, Progress in clinical and biological research.

The characterization of glucose-6-phosphate dehydrogenase in mouse ova.

C. Epstein, C. Smith, L. Kwok, 1970, Journal of reproduction and fertility.

Oxygen deprivation but not a combination of oxygen, glucose, and serum deprivation induces DNA degradation in mouse cortical neurons in vitro: attenuation by transgenic overexpression of CuZn-superoxide dismutase.

C. Epstein, P. Chan, L. Reola, 1996, Journal of neurotrauma.

Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

C. Epstein, S. Fahn, S. Przedborski, 1992, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Genetic control of the response to interferon.

C. Epstein, L. Epstein, 1981, Texas reports on biology and medicine.

GENFILES: a computerized medical genetics information network. III. Chromo: the cytogenetics database.

C. Epstein, W. Loughman, D. C. Mosher, 1980, American journal of medical genetics.

CHAPTER 34 – Educational Strategies in Genomic Medicine

C. Epstein, 2009 .

Evolution by gene duplication

C. Epstein, 1971 .

Genetic control of early mammalian development.

C. Epstein, T. Magnuson, 1982, Progress in clinical and biological research.

Absence of Mitochondrial Superoxide Dismutase Results in a Murine Hemolytic Anemia Responsive to Therapy with a Catalytic Antioxidant

C. Epstein, Ting-Ting Huang, R. Derby, 2001, Journal of Experimental Medicine.

Assignment of the gene for beta 2-microglobulin (B2m) to mouse chromosome 2.

D. Cox, C. Epstein, E. Appella, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Use of chromosome fluorescence in evaluating human chromosome fractionation.

C. Epstein, E. Schneider, 1971, Experimental cell research.

Embryonic development. Part A: Genetic aspects. Part B: Cellular aspects

C. Epstein, 1984 .

Voltage-activated sodium conductances in cultured normal and trisomy 16 dorsal root ganglion neurons from the fetal mouse.

C. Epstein, S. Rapoport, C. Orozco, 1988, Brain research.

Inactivation of the x-chromosome.

C. Epstein, 1972, The New England journal of medicine.

The chromosomal location of mouse interferon alpha genes.

D. Cox, M. Lovett, C. Epstein, 1984, The EMBO journal.