P. Leder

发表

S. Pestka, M. Nirenberg, O. W. Jones, 1963 .

The Neuroendocrine Protein 7B2 Is Required for Peptide Hormone Processing In Vivo and Provides a Novel Mechanism for Pituitary Cushing’s Disease

P. Leder, C. Westphal, L. Muller, 1999, Cell.

Mice Lacking p21 CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

Stephen J. Elledge, J. Wade Harper, S. Elledge, 1995, Cell.

A conserved role for the Hus1 checkpoint protein in eukaryotic genome maintenance.

P. Leder, R. Weiss, T. Enoch, 2000, Cold Spring Harbor symposia on quantitative biology.

Critical Role for Mouse Hus1 in an S-Phase DNA Damage Cell Cycle Checkpoint

P. Leder, R. Weiss, C. Vaziri, 2003, Molecular and Cellular Biology.

Inactivation of p53 tumor suppressor gene acts synergistically with c-neu oncogene in salivary gland tumorigenesis

P. Leder, C. Deng, S. Brodie, 2001, Oncogene.

A Network of Conserved Damage Survival Pathways Revealed by a Genomic RNAi Screen

Jianhua Ruan, Amy M. Wiles, Alexander J. R. Bishop, 2009, PLoS genetics.

A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints.

P. Leder, A. Ferguson-Smith, N. Youngson, 2008, Developmental cell.

Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance.

P. Leder, J. St-Pierre, V. Fantin, 2006, Cancer cell.

Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia

P. Leder, A. Luster, E. García-Zepeda, 1996, Nature Medicine.

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

P. Leder, W. Muller, William J. Muller, 1988, Cell.

Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome gene.

P. Leder, C. Kozak, F. Kuo, 1998, Genes & development.

A novel mitochondriotoxic small molecule that selectively inhibits tumor cell growth.

Luca Scorrano, S. Korsmeyer, P. Leder, 2002, Cancer cell.

Mammary Morphogenesis and Oncogenes

R. Cardiff, P. Leder, D. Ornitz, 1992 .

Butyric acid, a potent inducer of erythroid differentiation in cultured erythroleukemic cells

P. Leder, A. Leder, 1975, Cell.

Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation.

P. Leder, L. Weir, P Leder, 1984, Proceedings of the National Academy of Sciences of the United States of America.

F16, a Mitochondriotoxic Compound, Triggers Apoptosis or Necrosis Depending on the Genetic Background of the Target Carcinoma Cell

P. Leder, V. Fantin, Philip Leder, 2004, Cancer Research.

High-affinity binding site for a specific nuclear protein in the human IgM gene

P. Leder, L. Hennighausen, T. Kelly, 1985, Nature.

RNA Codewords and Protein Synthesis

M. Nirenberg, P. Leder, M NIRENBERG, 1964, Science.

RNA codewords and protein synthesis, VII. On the general nature of the RNA code.

M Nirenberg, M. Nirenberg, P. Leder, 1965, Proceedings of the National Academy of Sciences of the United States of America.

Comparison of cloned mouse alpha- and beta-globin genes: conservation of intervening sequence locations and extragenic homology.

J. Seidman, P. Leder, D. Hamer, 1978, Proceedings of the National Academy of Sciences of the United States of America.

SV40 T antigen transforms calcitonin cells of the thyroid but not CGRP-containing neurons in transgenic mice.

P. Leder, M. Fishman, E. Schmidt, 1991, Oncogene.

Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice.

P. Leder, C. Deng, C. Kozak, 1995, Genes & development.

Expression of the Mouse Pre-T Cell Receptor α Gene Is Controlled by an Upstream Region Containing a Transcriptional Enhancer

P. Leder, B. Reizis, 1999, The Journal of experimental medicine.

Leukemia inhibitory factor is expressed by the preimplantation uterus and selectively blocks primitive ectoderm formation in vitro.

P. Leder, M. Shen, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Purification and properties of biologically active messenger RNA for a myeloma light chain.

P. Leder, H. Aviv, D. Swan, 1972, Proceedings of the National Academy of Sciences of the United States of America.

Intervening sequence of DNA identified in the structural portion of a mouse beta-globin gene.

J. Seidman, J. Maizel, P. Leder, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Dispersion of alpha-like globin genes of the mouse to three different chromosomes.

P. D’Eustachio, P. Leder, F. Ruddle, 1981, Nature.

Parental legacy determines methylation and expression of an autosomal transgene: A molecular mechanism for parental imprinting

P. Leder, J. L. Swain, T. Stewart, 1987, Cell.

RNAi reveals anti-apoptotic and transcriptionally repressive activities of DAXX

P. Leder, J. Michaelson, 2003, Journal of Cell Science.

Homeodomain-Interacting Protein Kinase 1 Modulates Daxx Localization, Phosphorylation, and Transcriptional Activity

P. Leder, J. Michaelson, J. Ecsedy, 2003, Molecular and Cellular Biology.

A Mouse Model for Breast Cancer Induced by Amplification and Overexpression of the neu Promoter and Transgene

P. Leder, D. Kitsberg, E. Weinstein, 2000, Molecular medicine.

Association between a transposed α-globin pseudogene and retrovirus-like elements in the BALB/c mouse genome

P. Leder, K. Lueders, A. Leder, 1982, Nature.

Transgenic oncogene mice. Tumor phenotype predicts genotype.

R. Cardiff, P. Leder, E. Sinn, 1991, The American journal of pathology.

A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth

G. Daley, P. Leder, J. Brugge, 2004, Oncogene.

Nuclear localization and DNA binding properties of a protein expressed by human c-myc oncogene.

P. Leder, H. Persson, 1984, Science.

Wnt-10b directs hypermorphic development and transformation in mammary glands of male and female mice

P. Leder, T. Lane, 1997, Oncogene.

Translation of Phage Qβ mRNA: A Test of the Two-site Model for Ribosomal Function

P. Leder, D. Roufa, L. Skogerson, 1970, Nature.

The oncogene heregulin induces apoptosis in breast epithelial cells and tumors

P. Leder, S. Grimm, E. Weinstein, 1998, Oncogene.

P53 levels determine outcome during β-catenin tumor initiation and metastasis in the mammary gland and male germ cells

P. Leder, A. G. Ridgeway, J. McMenamin, 2006, Oncogene.

Characterization, expression, and evolution of the mouse embryonic zeta-globin gene

P. Leder, L. Weir, A. Leder, 1985, Molecular and cellular biology.

Loss of atm radiosensitizes multiple p53 null tissues.

P. Leder, C. Westphal, M. Kastan, 1998, Cancer research.

Loss of aim Radiosensitizes Multiple p53 Null Tissues1

Christoph, Kathryn, P. Leder, 2006 .

Genetic interactions between atm and p53 influence cellular proliferation and irradiation-induced cell cycle checkpoints.

P. Leder, C. Westphal, D. Fisher, 1997, Cancer research.

atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity

P. Leder, C. Westphal, D. Fisher, 1997, Nature Genetics.

An embryonically expressed gene is a target for c-Myc regulation via the c-Myc-binding sequence.

P. Leder, N. Benvenisty, A. Kuo, 1992, Genes & development.

Expression of c-MYC under the control of GATA-1 regulatory sequences causes erythroleukemia in transgenic mice

P. Leder, S. Orkin, S. Tsai, 1995, The Journal of experimental medicine.

Association of Elevated Protein Kinase CK2 Activity with Aggressive Behavior of Squamous Cell Carcinoma of the Head and Neck

P. Leder, K. Ahmed, G. Adams, 1995, Molecular medicine.

A differential display strategy identifies Cryptic, a novel EGF-related gene expressed in the axial and lateral mesoderm during mouse gastrulation.

P. Leder, M. Shen, H. Wang, 1997, Development.

Multiple immunoglobulin switch region homologies outside the heavy chain constant region locus

P. Leder, E. E. Max, I. Kirsch, 1981, Nature.

Recombination events that activate, diversify, and delete immunoglobulin genes.

J. Seidman, P. Leder, E. E. Max, 1981, Cold Spring Harbor symposia on quantitative biology.

Trans-acting elements modulate expression of the human c-myc gene in Burkitt lymphoma cells.

P. Leder, R. Reed, J. Chung, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Transgenic mice bearing the human c-myc gene activated by an immunoglobulin enhancer: a pre-B-cell lymphoma model.

P. Leder, E. Schmidt, L. Weir, 1988, Proceedings of the National Academy of Sciences of the United States of America.

A human immunoglobulin gene reduces the incidence of lymphomas in c-Myc-bearing transgenic mice

P. Leder, M. Nussenzweig, E. Schmidt, 1988, Nature.

A novel alteration in the structure of an activated c-myc gene in a variant t(2;8) burkitt lymphoma

S. Latt, P. Leder, G. Lenoir, 1984, Cell.

A variant translocation places the λ immunoglobulin genes 3′ to the c-myc oncogene in Burkitt's lymphoma

P. Leder, G. Lenoir, J. Battey, 1984, Nature.

Antibodies to human c-myc oncogene product: evidence of an evolutionarily conserved protein induced during cell proliferation.

P. Leder, W. DeGrado, L. Hennighausen, 1984, Science.

A Murine Homologue of the Drosophila brainiac Gene Shows Homology to Glycosyltransferases and Is Required for Preimplantation Development of the Mouse

P. Leder, K. Fitzgerald, B. Vollrath, 2001, Molecular and Cellular Biology.

Targeted Disruption of the Chemokine Eotaxin Partially Reduces Antigen-induced Tissue Eosinophilia

P. Leder, A. Luster, E. Pearlman, 1997, The Journal of experimental medicine.

Formin-1 protein associates with microtubules through a peptide domain encoded by exon-2.

P. Leder, Fen Zhou, Stuart S. Martin, 2006, Experimental cell research.

Casein kinase II alpha transgene-induced murine lymphoma: relation to theileriosis in cattle

P. Leder, DC Seldin, David C Seldin, 1995, Science.

Multiple tumor types appear in a transgenic mouse with the ras oncogene.

R. Cardiff, P. Leder, A. Kuo, 1993, The American journal of pathology.

A processed human immunoglobulin epsilon gene has moved to chromosome 9.

P. Leder, E. E. Max, J. Battey, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Mapping of the human Blym-1 transforming gene activated in Burkitt lymphomas to chromosome 1.

P. Leder, C. Morton, G. Cooper, 1984, Science.

Gene replacement with the human BRCA1 locus: tissue specific expression and rescue of embryonic lethality in mice

P. Leder, Melissa A. Brown, E. Solomon, 2000, Oncogene.

Formins: phosphoprotein isoforms encoded by the mouse limb deformity locus.

P. Leder, J. Rush, T. Vogt, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Cytoplasmic tail deletion converts membrane immunoglobulin to a phosphatidylinositol-linked form lacking signaling and efficient antigen internalization functions.

P. Leder, R. Mitchell, A. Shaw, 1991, The Journal of biological chemistry.

Benign prostatic hyperplasia in a transgenic mouse: a new hormonally sensitive investigatory model.

J. Richie, P. Leder, D. Ornitz, 1993, The Journal of urology.

Fibroblast growth factor receptor-1 (FGFR-1) is essential for normal neural tube and limb development.

P. Leder, C. Deng, M. Bedford, 1997, Developmental biology.

The int‐2 gene product acts as an epithelial growth factor in transgenic mice.

P. Leder, G. Peters, W. Muller, 1990, The EMBO journal.

Neu Differentiation Factor (NDF), a Dominant Oncogene, Causes Apoptosis In Vitro and In Vivo

P. Leder, S. Grimm, E. Weinstein, 1998, The Journal of experimental medicine.

SV40 recombinants carrying rabbit β-globin gene coding sequences

P. Leder, D. Hamer, S. Boyer, 1979, Cell.

SV40 recombinants carrying a functional RNA splice junction and polyadenylation site from the chromosomal mouse βmaj globin gene

P. Leder, D. Hamer, 1979, Cell.

Polydactylous limbs in Strong's Luxoid mice result from ectopic polarizing activity.

P. Leder, C. Tabin, E. Laufer, 1995, Development.

Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins.

T. Waldmann, S. Korsmeyer, P. Leder, 1983, The Journal of clinical investigation.

Lymphohematopoietic and other malignant neoplasms occurring spontaneously in transgenic mice carrying and expressing MTV/myc fusion genes.

P. Leder, A. Kuo, P. Pattengale, 1986, Current topics in microbiology and immunology.

Variable amplification of immunoglobulin λ light-chain genes in human populations

T. Waldmann, S. Korsmeyer, P. Leder, 1983, Nature.

The effect of translocations on the cellular myc gene in burkitt lymphomas

P. Leder, R. Taub, G. Hollis, 1984, Journal of cellular physiology. Supplement.

Ligand specificity and heparin dependence of fibroblast growth factor receptors 1 and 3.

P. Leder, D. Ornitz, 1992, The Journal of biological chemistry.

The human homologs of the raf (mil) oncogene are located on human chromosomes 3 and 4.

S. O’Brien, P. Leder, W. Nash, 1984, Science.

Mutations of immunoglobulin transmembrane and cytoplasmic domains: Effects on intracellular signaling and antigen presentation

P. Leder, R. Mitchell, A. Shaw, 1990, Cell.

Murine c‐mpl: a member of the hematopoietic growth factor receptor superfamily that transduces a proliferative signal.

P. Leder, D. Seldin, T. Vogt, 1993, The EMBO journal.

The intervening sequence of a mouse beta-globin gene is transcribed within the 15S beta-globin mRNA precursor.

P. Leder, S. Tilghman, P. Curtis, 1978, Proceedings of the National Academy of Sciences of the United States of America.

In vitro synthesis of DNA complementary to purified rabbit globin mRNA (RNA-dependent DNA polymerase-reticulocyte-hemoglobin-density gradient centrifugation-oligo(dT) primer).

P. Leder, E. Scolnick, H. Aviv, 1972, Proceedings of the National Academy of Sciences of the United States of America.

Formin isoforms are differentially expressed in the mouse embryo and are required for normal expression of fgf-4 and shh in the limb bud.

P. Leder, A. Wynshaw-Boris, D. Chan, 1995, Development.

The Bloom's Syndrome Helicase Is Critical for Development and Function of the αβ T-Cell Lineage

P. Leder, B. Reizis, N. Chester, 2007, Molecular and Cellular Biology.

The Bloom’s Syndrome Helicase Is Critical for Development and Function of the (cid:2)(cid:3) T-Cell Lineage (cid:1) †

P. Leder, B. Reizis, N. Chester, 2007 .

zeta-/- Thalassemic mice are affected by two modifying loci and display unanticipated somatic recombination leading to inherited variation.

P. Leder, A. Bishop, A. Leder, 2005, Human molecular genetics.

Characterization, Expression, and Evolution of the Mouse Embryonic 4-Globin Gene

P. Leder, L. Weir, A. Leder, 2022 .

Complete nucleotide sequence of the membrane form of the human IgM heavy chain.

P. Leder, M. Nussenzweig, R. Friedlander, 1990, Nucleic acids research.

Molecular mechanism for immunoglobulin double-isotype expression.

P. Leder, M. Nussenzweig, T. Honjo, 1989, Cold Spring Harbor symposia on quantitative biology.

Chromosome instability and tumor predisposition inversely correlate with BLM protein levels.

P. Leder, A. Borowsky, L. McDaniel, 2003, DNA repair.

The protein tyrosine phosphatase epsilon gene maps to mouse chromosome 7 and human chromosome 10q26.

P. Leder, S. Weremowicz, C. Morton, 1996, Genomics.

An intervening sequence of the mouse β-globin major gene shares extensive homology only with β-globin genes

P. Leder, H. Miller, D. Konkel, 1978, Nature.

Cell Cycle Control of C-Myc Expression

P. Leder, C. Stiles, B. Cochran, 1985 .

The regulation of c-myc by growth signals.

P. Leder, C. Stiles, B. Cochran, 1984, Current topics in microbiology and immunology.

Dispersion of α-like globin genes of the mouse to three different chromosomes

P. D’Eustachio, P. Leder, F. Ruddle, 1981, Nature.

Nucleic acid and protein sequences of phosphocholine-binding light chains

J. Seidman, P. Leder, S. Rudikoff, 1981, The Journal of experimental medicine.

Variation in the crossover point of kappa immunoglobulin gene V-J recombination: Evidence from a cryptic gene

J. Seidman, P. Leder, E. E. Max, 1980, Cell.

Eotaxin Triggers Eosmophil-Selective Chemotaxis and Calcium Flux via a Distinct Receptor and Induces Pulmonary Eosinophilia in the Presence of Interleukin 5 in Mice

M. van de Rijn, P. Leder, J. Bonventre, 1996, Molecular medicine.

Transgenic expression of interleukin 7 restores T cell populations in nude mice

P. Leder, B. Rich, 1995, The Journal of experimental medicine.

Role of an RNA cleavage/poly(A) addition site in the production of membrane-bound and secreted IgM mRNA.

P. Leder, D. Danner, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Deformylation and protein biosynthesis.

P. Leder, D. Livingston, 1969, Biochemistry.

Purification and translation of an immunoglobulin lambda chain messenger RNA from mouse myeloma.

P. Leder, T. Honjo, D. Swan, 1976, Biochemistry.

THE ORGANIZATION OF IMMUNOGLOBULIN GENES

P. Leder, T. Honjo, M. Nau, 1974 .

The maturation of a pre-B cell to an immunoglobulin (Ig)-bearing B cell requires an effective recombination of a light chain variable (VL)

T. Waldmann, S. Korsmeyer, P. Leder, 2003 .

Normal human B cells display ordered light chain gene rearrangements and deletions

T. Waldmann, S. Korsmeyer, P. Leder, 1982, The Journal of experimental medicine.

A receptor binding domain of mouse interleukin-4 defined by a solid-phase binding assay and in vitro mutagenesis.

P. Leder, B. W. Morrison, Briggs W. Morrison, 1992, The Journal of biological chemistry.

Purification and cloning of a mouse ribosomal gene fragment in coliphage lambda.

P. Leder, S. Tilghman, D. Tiemeier, 1977, Gene.

The Sequence of the Chromosomal Mouse /3-Globin Major Gene: Homologies in Capping, Splicing and

P. Leder, S. Tilghman, D. Konkel, 1978 .

Transposon-generated ‘knock-out’ and ‘knock-in’ gene-targeting constructs for use in mice

P. Leder, C. Westphal, 1997, Current Biology.

Formin-2, a novel formin homology protein of the cappuccino subfamily, is highly expressed in the developing and adult central nervous system

P. Leder, B. Leader, 2000, Mechanisms of Development.

Insertional mutagenesis identifies a member of the Wnt gene family as a candidate oncogene in the mammary epithelium of int-2/Fgf-3 transgenic mice.

P. Leder, G. Shackleford, A. Kuo, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Protein synthesis directed by encephalomyocarditis virus mRNA. 3. Discrete polypeptides translated from a monocistronic messenger in vitro.

P. Leder, I. Boime, 1972, Archives of biochemistry and biophysics.

Characterization of synthetic rabbit globin DNA.

P. Leder, H. Aviv, J. Ross, 1973, Archives of biochemistry and biophysics.

Transcription of mouse kappa chain genes: implications for allelic exclusion.

S. Tonegawa, J. Seidman, P. Leder, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Regulating Gene Expression in Mammalian Cell Culture and Transgenic Mice with Yeast GAL4/UAS Control Elements

P. Leder, R. Skoda, D. Ornitz, 1992 .

Genetic Evidence That Formins Function within the Nucleus*

P. Leder, D. Chan, 1996, The Journal of Biological Chemistry.

Cloning specific segments of the mammalian genome: bacteriophage lambda containing mouse globin and surrounding gene sequences.

J. Seidman, P. Leder, M. Edgell, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Molecular characterization of transgene-induced immunodeficiency in B- less mice using a novel quantitative limiting dilution polymerase chain reaction method

P. Leder, D. Levinson, J. Campos-Torres, 1993, The Journal of experimental medicine.

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

P. Leder, C. Stiles, B. Cochran, 1983, Cell.

RIP and FADD: two "death domain"-containing proteins can induce apoptosis by convergent, but dissociable, pathways.

P. Leder, S. Grimm, B. Stanger, 1996, Proceedings of the National Academy of Sciences of the United States of America.

The two site model of ribosomal function: a test using degenerate serine codons in bacteriophage f2 mRNA.

P. Leder, B. P. Doctor, D. Roufa, 1970, Biochemical and biophysical research communications.

Mutational analysis of a critical signaling domain of the human interleukin 4 receptor.

P. Leder, D. Seldin, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Differentiation of erythroleukemic cells in the presence of inhibitors of DNA synthesis

P. Leder, S. Orkin, A. Leder, 1975, Science.

A comparison of globin genes in duck reticulocytes and liver cells.

P. Leder, H. Aviv, J. Ross, 1972, Biochemical and biophysical research communications.

Protein synthesis directed by encephalomyocarditis virus RNA: properties of a transfer RNA-dependent system.

P. Leder, H. Aviv, I. Boime, 1971, Proceedings of the National Academy of Sciences of the United States of America.

The mast cell-specific expression of a protease gene, RMCP II, is regulated by an enhancer element that binds specifically to mast cell trans-acting factors.

P. Benfey, P. Leder, J. Sarid, 1989, The Journal of biological chemistry.

Cloning of the mast cell protease, RMCP II. Evidence for cell-specific expression and a multi-gene family.

P. Benfey, P. Leder, F. H. Yin, 1987, The Journal of biological chemistry.

[165a] Enzymatic synthesis of trinucleoside diphosphates of known sequence

P. Leder, 1968 .

Unusual a-globin-like gene that has cleanly lost both globin intervening sequences ( gene conversion / recombinant DNA )

P. Leder, A. Leder, Y. Nishioka, 2022 .

Initiation of protein synthesis II. A convenient assay for the ribosome-dependent synthesis of N-formyl-C14-methionylpuromycin.

P. Leder, H. Bursztyn, 1966, Biochemical and biophysical research communications.

THE ORGANIZATION AND DIVERSITY OF IMMUNOGLOBULIN κ AND λ GENES

P. Leder, T. Honjo, M. Nau, 1975 .

Transgenes expressing the Wnt-1 and int-2 proto-oncogenes cooperate during mammary carcinogenesis in doubly transgenic mice

H. Varmus, P. Leder, G. Tristram, 1992, Molecular and cellular biology.

A mouse globin gene promoter is functional in SV40

P. Leder, D. Hamer, M. Kaehler, 1980, Cell.

B-less: a strain of profoundly B cell-deficient mice expressing a human lambda transgene

D. A. Levinson, P. Leder, E. Schmidt, 1992, The Journal of experimental medicine.

Expression of LIF in transgenic mice results in altered thymic epithelium and apparent interconversion of thymic and lymph node morphologies.

R. Cardiff, P. Leder, R. Skoda, 1994, The EMBO journal.

Human and rat mast cell high-affinity immunoglobulin E receptors: characterization of putative alpha-chain gene products.

P. Benfey, P. Leder, A. Shimizu, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Translocations among antibody genes in human cancer.

P. Leder, 2019, IARC scientific publications.

Genetic control of immunoglobulin production.

P. Leder, 1983, Hospital practice.

Int-2, an autocrine and/or ultra-short-range effector in transgenic mammary tissue transplants.

R. Cardiff, P. Leder, A. Kuo, 1992, Journal of the National Cancer Institute.

A Novel Pro-Arg Motif Recognized by WW Domains*

P. Leder, M. Yaffe, Jian Xu, 2000, The Journal of Biological Chemistry.

SV40 recombinants carrying rabbit beta-globin gene coding sequences.

P. Leder, D. Hamer, S. Boyer, 1979, Cell.

High capacity gel preparative electrophoresis for purification of fragments of genomic DNA.

J. Seidman, P. Leder, M. Edgell, 1978, Analytical biochemistry.

Rescuing the in vitro function of a globin pseudogene promoter

P. Leder, C. Talkington, 1982, Nature.

Translation and translocation of defined RNA messengers.

P. Leder, M. Nau, R. Erbe, 1969, Journal of molecular biology.

Genetic interaction between the unstable v-Ha-RAS transgene (Tg.AC) and the murine Werner syndrome gene: transgene instability and tumorigenesis

P. Leder, A. Bishop, Fen Zhou, 2002, Oncogene.

Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose.

P. Leder, H. Aviv, H Aviv, 1972, Proceedings of the National Academy of Sciences of the United States of America.

Mitochondriotoxic compounds for cancer therapy

P. Leder, V. Fantin, 2006, Oncogene.

Evolution of human immunoglobulin kappa J region genes.

J. Maizel, P. Leder, P. Hieter, 1982, The Journal of biological chemistry.

Clustered arrangement of immunoglobulin λ constant region genes in man

T. Waldmann, S. Korsmeyer, P. Leder, 1981, Nature.

Murine eotaxin: an eosinophil chemoattractant inducible in endothelial cells and in interleukin 4-induced tumor suppression.

P. Leder, A. Luster, M. Rothenberg, 1995, Proceedings of the National Academy of Sciences of the United States of America.

The cytomegalovirus enhancer: a pan-active control element in transgenic mice

P. Leder, E. Schmidt, R. Zeller, 1990, Molecular and cellular biology.

Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells

J G Flanagan, P. Leder, J. Flanagan, 1992, Molecular and cellular biology.

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells.

P. Leder, C. Morton, G. Lenoir, 1982, Proceedings of the National Academy of Sciences of the United States of America.

The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus

P. Leder, E. Huang, D. Beier, 1990, Cell.

Fibroblast Growth Factor Receptor 3 Is a Negative Regulator of Bone Growth

P. Leder, C. Deng, A. Wynshaw-Boris, 1996, Cell.

Functional role for c-myc in mitogenic response to platelet-derived growth factor

P. Leder, T. Stewart, C. Stiles, 1984, Nature.

Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the SId mutant

P. Leder, J. Flanagan, D. Chan, 1991, Cell.

RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

P. Leder, B. Seed, B. Stanger, 1995, Cell.

Mouse globin system: a functional and evolutionary analysis.

P. Leder, J. Hansen, A. Leder, 1980, Science.

Differentiation in erythroleukemic cells and their somatic hybrids.

P. Leder, S. Orkin, F. I. Hárosi, 1975, Proceedings of the National Academy of Sciences of the United States of America.

Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments

J. Seidman, J. Maizel, P. Leder, 1980, Cell.

Splicing and the formation of stable RNA

P. Leder, D. Hamer, 1979, Cell.

Globin gene expression in cultured erythroleukemic cells.

P. Leder, Y. Ikawa, J. Ross, 1974, Journal of molecular biology.

Arginine Methylation Inhibits the Binding of Proline-rich Ligands to Src Homology 3, but Not WW, Domains*

Michael B. Yaffe, Steven Clarke, P. Leder, 2000, The Journal of Biological Chemistry.

Pleiotropic defects in ataxia-telangiectasia protein-deficient mice.

P. Leder, C. Morton, A. Elson, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Potential Function of the Werner’s Syndrome Homologue in the African Clawed Frog and the Mouse

P. Leder, M. Lebel, 2004 .

High-affinity binding site for a specific nuclear protein in the human IgM gene

P. Leder, L. Hennighausen, T. Kelly, 1985 .

Differential expression of alpha- and beta-globin genes during differentiation of cultured erythroleukemic cells.

P. Leder, S. Orkin, D. Swan, 1975, The Journal of biological chemistry.

Initiation of protein synthesis,I. Effect of formylation of methionyl-tRNA on codon recognition.

P. Leder, H. Bursztyn, 1966, Proceedings of the National Academy of Sciences of the United States of America.

Chromosomal location of human kappa and lambda immunoglobulin light chain constant region genes

P. Leder, P. Hieter, O. Mcbride, 1982, The Journal of experimental medicine.

The kit ligand: A cell surface molecule altered in steel mutant fibroblasts

P. Leder, J. Flanagan, 1990, Cell.

Structure of the human immunoglobulin μ locus: Characterization of embryonic and rearranged J and D genes

Ulrich Siebenlist, T. Waldmann, S. Korsmeyer, 1981, Cell.

Activation and somatic mutation of the translocated c-myc gene in Burkitt lymphoma cells

P. Leder, T. Vasicek, G. Lenoir, 1984, Cell.

The human c-myc oncogene: Structural consequences of translocation into the igh locus in Burkitt lymphoma

P. Leder, G. Lenoir, J. Battey, 1983, Cell.

Human immunoglobulin heavy chain genes map to a region of translocations in malignant B lymphocytes.

P. Leder, C. Morton, I. Kirsch, 1982, Science.

Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells.

T. Waldmann, S. Korsmeyer, P. Leder, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: Synergistic action of oncogenes in vivo

P. Leder, E. Sinn, P. Pattengale, 1987, Cell.

Consequences of widespread deregulation of the c-myc gene in transgenic mice: Multiple neoplasms and normal development

P. Leder, A. Kuo, P. Pattengale, 1986, Cell.

The limb deformity gene is required for apical ectodermal ridge differentiation and anteroposterior limb pattern formation.

P. Leder, R. Zeller, L. Jackson-Grusby, 1989, Genes & development.

An inherited limb deformity created by insertional mutagenesis in a transgenic mouse

L. G. Davis, P. D’Eustachio, P. Leder, 1985, Nature.

In vitro initiation of coliphage T7 mRNA.

P. Leder, R. Callahan, 1972, Archives of biochemistry and biophysics.

In vitro transcription of normal, mutant, and truncated mouse alpha-globin genes.

P. Leder, Y. Nishioka, C. Talkington, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Globin messenger-RNA induction during erythroid differentiation of cultured leukemia cells.

P. Leder, Y. Ikawa, J. Ross, 1972, Proceedings of the National Academy of Sciences of the United States of America.

The Death Domain Kinase RIP Mediates the TNF-Induced NF-κB Signal

Stefan Grimm, Yasumasa Ishida, P. Leder, 1998 .

v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: effects of phorbol esters and retinoic acid.

R. Cardiff, P. Leder, A. Kuo, 1990, Proceedings of the National Academy of Sciences of the United States of America.

c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

Michael E. Greenberg, M. Greenberg, P. Leder, 1988, Cell.

Isolation of a Murine Homologue of the Drosophila neuralized Gene, a Gene Required for Axonemal Integrity in Spermatozoa and Terminal Maturation of the Mammary Gland

P. Leder, S. Asa, K. Fitzgerald, 2001, Molecular and Cellular Biology.

the Mammary Gland Spermatozoa and Terminal Maturation of Required for Axonemal Integrity in Gene , a Gene Drosophila neuralized Isolation of a Murine Homologue of the

P. Leder, S. Asa, K. Fitzgerald, 2001 .

Murine FGFR-1 is required for early postimplantation growth and axial organization.

P. Leder, C. Deng, A. Wynshaw-Boris, 1994, Genes & development.

Ras pathway signals are required for notch-mediated oncogenesis

P. Leder, K. Fitzgerald, Anne N. Harrington, 2000, Oncogene.

A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity.

P. Leder, M. Lebel, 1998, Proceedings of the National Academy of Sciences of the United States of America.

The sequence of a mouse embryonic beta-globin gene. Evolution of the gene and its signal region.

P. Leder, J. Hansen, D. Konkel, 1982, The Journal of biological chemistry.

The evolution and sequence comparison of two recently diverged mouse chromosomal β-globin genes

J. Maizel, P. Leder, D. Konkel, 1979, Cell.

The sequence of the chromosomal mouse β-globin major gene: Homologies in capping, splicing and poly(A) sites

P. Leder, S. Tilghman, D. Konkel, 1978, Cell.

Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction.

P. Leder, C. Deng, Xiaoling Xu, 1998, Development.

Processed genes: a dispersed human immunoglobulin gene bearing evidence of RNA-type processing

P. Leder, P. Hieter, O. Mcbride, 1982, Nature.

MOVING GENES: PROMISES KEPT AND PENDING

P. Leder, G. Hollis, A. Leder, 1982 .

Duplication and deletion in the human immunoglobulin ϵ genes

P. Leder, E. E. Max, I. Kirsch, 1982, Cell.

Parental-specific methylation of an imprinted transgene is established during gametogenesis and progressively changes during embryogenesis

P. Leder, D. Beier, T. Vogt, 1991, Cell.

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

Jeffrey D. Esko, Avner Yayon, P. Leder, 1991, Cell.

Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway.

Boris Reizis, P. Leder, B. Reizis, 2002, Genes & development.

Plasmacytoid dendritic cells activate lymphoid-specific genetic programs irrespective of their cellular origin.

P. Leder, K. Akashi, H. Iwasaki, 2004, Immunity.

Tal‐1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha.

P. Leder, D. Seldin, M. Kelliher, 1996, The EMBO journal.

Translocations among antibody genes in human cancer.

P. Leder, G. Lenoir, J. Battey, 1983, Science.

The Role of a Single Formin Isoform in the Limb and Renal Phenotypes of Limb Deformity

P. Leder, C. Deng, A. Wynshaw-Boris, 1997, Molecular medicine.

Unusual alpha-globin-like gene that has cleanly lost both globin intervening sequences.

P. Leder, A. Leder, Y. Nishioka, 1980, Proceedings of the National Academy of Sciences of the United States of America.

A comparison of two cloned mouse β-globin genes and their surrounding and intervening sequences

J. Seidman, P. Leder, M. Edgell, 1978, Cell.

Localization of human variable and constant region immunoglobulin heavy chain genes on subtelomeric band q32 of chromosome 14.

P. Leder, O. Mcbride, J. Battey, 1982, Nucleic acids research.

Globin genes: a paradigm of gene structure, function, and evolution.

P. Leder, A. Leder, Y. Nishioka, 1982, National Cancer Institute monograph.

Transcription and promoter usage of the myc gene in normal somatic and spermatogenic cells.

P. Leder, A. Bellvé, T. Stewart, 1984, Science.

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

P. Leder, P. Pattengale, T. Stewart, 1984, Cell.

Chromatin structure and protein binding in the putative regulatory region of the c-myc gene in burkitt lymphoma

P. Leder, L. Hennighausen, J. Battey, 1984, Cell.

The arrangement and rearrangement of antibody genes

J. Seidman, P. Leder, Jonathan G. Seidman, 1978, Nature.

NDF/heregulin induces persistence of terminal end buds and adenocarcinomas in the mammary glands of transgenic mice.

P. Leder, I. Krane, Krane Im, 1996, Oncogene.

Evolutionarily conserved regions of the human c-myc protein can be uncoupled from transforming activity.

P. Leder, T. Halazonetis, W. Murphy, 1987, Proceedings of the National Academy of Sciences of the United States of America.

The Upstream Enhancer Is Necessary and Sufficient for the Expression of the Pre-T Cell Receptor α Gene in Immature T Lymphocytes

P. Leder, B. Reizis, 2001, The Journal of experimental medicine.

Loss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse development.

P. Leder, C. Kozak, F. Kuo, 1999, Genes & development.

Correction: A Network of Conserved Damage Survival Pathways Revealed by a Genomic RNAi Screen

Amy M. Wiles, P. Leder, Jianhua Ruan, 2009, PLoS Genetics.

The complete sequence of a chromosomal mouse α-globin gene reveals elements conserved throughout vertebrate evolution

P. Leder, Y. Nishioka, 1979, Cell.

Expression of the chromosomal mouse βmaj-globin gene cloned in SV40

P. Leder, D. Hamer, 1979, Nature.

The death domain kinase RIP mediates the TNF-induced NF-kappaB signal.

P. Leder, S. Grimm, F. Kuo, 1998, Immunity.

A human gene homologous to the formin gene residing at the murine limb deformity locus: chromosomal location and RFLPs.

P. Leder, R. Eddy, T. Shows, 1991, American journal of human genetics.

Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice.

P. Leder, A. Elson, Y. Wang, 1997, Proceedings of the National Academy of Sciences of the United States of America.

A κ-immunoglobulin gene is formed by site-specific recombination without further somatic mutation

J. Seidman, P. Leder, E. E. Max, 1979, Nature.

Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene.

J. Seidman, P. Leder, E. E. Max, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Polydactyly in the Strong's luxoid mouse is suppressed by limb deformity alleles.

P. Leder, T. Vogt, 1996, Developmental genetics.

The c-myc gene encodes superimposed RNA polymerase II and III promoters

P. Leder, R. Zeller, Jay H. Chung, 1987, Cell.

An association between globin messenger RNA and 60S RNA derived from Friend leukemia virus.

P. Leder, Y. Ikawa, J. Ross, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Human immunoglobulin κ light-chain genes are deleted or rearranged in λ-producing B cells

T. Waldmann, S. Korsmeyer, P. Leder, 1981, Nature.

Human immunoglobulin kappa light-chain genes are deleted or rearranged in lambda-producing B cells.

T. Waldmann, S. Korsmeyer, P. Leder, 1981, Nature.

Clustered arrangement of immunoglobulin lambda constant region genes in man.

T. Waldmann, S. Korsmeyer, P. Leder, 1981, Nature.

IP-10, a -C-X-C- chemokine, elicits a potent thymus-dependent antitumor response in vivo

P. Leder, A. Luster, 1993, The Journal of experimental medicine.

Tumorigenic effect of nonfunctional p53 or p21 in mice mutant in the Werner syndrome helicase.

R. Cardiff, P. Leder, M. Lebel, 2001, Cancer research.

Philip Leder in the Werner Syndrome Helicase Tumorigenic Effect of Nonfunctional p 53 or p 21 in Mice Mutant

R. Cardiff, P. Leder, M. Lebel, 2001 .

Genomic Instability Resulting from Blm Deficiency Compromises Development, Maintenance, and Function of the B Cell Lineage1

P. Leder, S. Rodig, M. Reth, 2009, The Journal of Immunology.

Formin-2, polyploidy, hypofertility and positioning of the meiotic spindle in mouse oocytes

P. Leder, R. Maas, D. Pellman, 2002, Nature Cell Biology.

Number : DAMD 17-021-0402 TITLE : Characterization of Two Novel Oncogenic Pathways Collaborating with Loss of p 53 or Activated Neu in Mouse Models of Breast Cancer

Jianrong, P. Leder, D. Ph., 2022 .

Human MCF10A Mammary Epithelial Cells Undergo Apoptosis following Actin Depolymerization That Is Independent of Attachment and Rescued by Bcl-2

P. Leder, Stuart S. Martin, S. Martin, 2001, Molecular and Cellular Biology.

Protein kinase expression during murine mammary development.

H. Gardner, L. Chodosh, P. Leder, 2000, Developmental biology.

Allelic exclusion in transgenic mice that express the membrane form of immunoglobulin mu.

P. Leder, M. Nussenzweig, A. Shaw, 1987, Science.

Tracing lymphopoiesis with the aid of a pTα-controlled reporter gene

P. Leder, F. Gounari, H. Fehling, 2002, Nature Immunology.

The extracellular region of heregulin is sufficient to promote mammary gland proliferation and tumorigenesis but not apoptosis.

P. Leder, E. Weinstein, 2000, Cancer research.

Parental legacy determines methylation and myocardial expression of an autosomal fusion gene carried by a transgenic mouse

P. Leder, J. L. Swain, T. Stewart, 1987 .

A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression

N. Perrimon, P. Leder, Jianrong Lu, 2007, Proceedings of the National Academy of Sciences.

Murine interleukin-4 displays potent anti-tumor activity in vivo

P. Leder, R. Tepper, P. Pattengale, 1989, Cell.

'Formins': proteins deduced from the alternative transcripts of the limb deformity gene

P. Leder, R. Maas, R. Zeller, 1990, Nature.

An eosinophil-dependent mechanism for the antitumor effect of interleukin-4.

P. Leder, R. Coffman, R. Tepper, 1992, Science.

Two kappa immunoglobulin genes are expressed in the myeloma S107

J. Seidman, P. Leder, E. E. Max, 1981, Cell.

Variable amplification of immunoglobulin lambda light-chain genes in human populations.

T. Waldmann, S. Korsmeyer, P. Leder, 1983, Nature.

Human immunoglobulin D segments encoded in tandem multigenic families

T. Waldmann, S. Korsmeyer, P. Leder, 1981, Nature.

Evolutionary approach to the question of immunoglobulin heavy chain switching: evidence from cloned human and mouse genes.

P. Leder, I. Kirsch, J. Ravetch, 1980, Proceedings of the National Academy of Sciences of the United States of America.

The organization and diversity of immunoglobulin genes.

P. Leder, T. Honjo, M. Nau, 1974, Proceedings of the National Academy of Sciences of the United States of America.

A bifunctional targeted peptide that blocks HER-2 tyrosine kinase and disables mitochondrial function in HER-2-positive carcinoma cells.

P. Leder, M. Berardi, V. Fantin, 2005, Cancer research.

Animal models of human disease. Pathology and molecular biology of spontaneous neoplasms occurring in transgenic mice carrying and expressing activated cellular oncogenes.

P. Leder, E. Schmidt, E. Sinn, 1989, The American journal of pathology.

Detection of a frequent restriction fragment length polymorphism in the human T cell antigen receptor beta chain locus. A potential diagnostic tool.

J. Seidman, P. Leder, C. Morton, 1985, The Journal of clinical investigation.

Chromatin structure of the human c-myc oncogene: definition of regulatory regions and changes in Burkitt's lymphomas.

P. Leder, L. Hennighausen, J. Battey, 1985, Haematology and blood transfusion.

Chromatin structural changes in the putative regulatory region of c-myc accompany the translocation in a Burkitt lymphoma.

P. Leder, L. Hennighausen, J. Battey, 1984, Current topics in microbiology and immunology.

Identifying genes preferentially expressed in undifferentiated embryonic stem cells

P. Leder, Xiajun Li, 2007, BMC Cell Biology.

Regulated expression of mammalian genes: globin and immunoglobulin as model systems.

P. Leder, Y. Ikawa, H. Aviv, 1974, Cold Spring Harbor symposia on quantitative biology.

The nucleotide sequence of a 5.5-kilobase DNA segment containing the mouse kappa immunoglobulin J and C region genes.

J V Maizel, J. Maizel, P. Leder, 1981, The Journal of biological chemistry.

Structure and Expression of the Human Immunoglobulin X Genes

P. Leder, T. Vasicek, 2003 .

Structure and expression of the human immunoglobulin lambda genes

P. Leder, T. Vasicek, 1990, The Journal of experimental medicine.

Identification of three new Ig lambda-like genes in man

E. Dmitrovsky, P. Leder, P. Hieter, 1986, The Journal of experimental medicine.

A conserved sequence in the immunoglobulin Jκ–Cκ intron: possible enhancer element

P. Leder, M. Kuehl, E. E. Max, 1983, Nature.

The Formation of Antibody Variable Region Genes

P. Leder, 1983 .

Allelic exclusion in transgenic mice carrying mutant human IgM genes

P. Leder, M. Nussenzweig, A. Shaw, 1988, The Journal of experimental medicine.

Immunoglobulin γ1 heavy chain gene: Structural gene sequences cloned in a bacterial plasmid

J. Seidman, P. Leder, T. Honjo, 1980 .

FBP WW domains and the Abl SH3 domain bind to a specific class of proline‐rich ligands

P. Leder, M. Bedford, D. Chan, 1997, The EMBO journal.

Immunoglobulin V/J recombination is accompanied by deletion of joining site and variable region segments.

S P Kwan, J. Seidman, P. Leder, 1980, Proceedings of the National Academy of Sciences of the United States of America.

β-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland

P. Leder, J. Michaelson, 2001, Oncogene.

The MMTV/c-myc transgene and p53 null alleles collaborate to induce T-cell lymphomas, but not mammary carcinomas in transgenic mice.

L. Donehower, P. Leder, C. Deng, 1995, Oncogene.

J. Seidman, P. Leder, M. Edgell, 1978, Proceedings of the National Academy of Sciences of the United States of America.

B-less : a Strain of Profoundly B Cell-deficient Mice Expressing a Human ~ , Transgene By

D. A. Levinson, P. Leder, E. Schmidt, 2003 .

Binary system for regulating transgene expression in mice: targeting int-2 gene expression with yeast GAL4/UAS control elements.

P. Leder, D. Ornitz, R. Moreadith, 1991, Proceedings of the National Academy of Sciences of the United States of America.

neu and ras initiate murine mammary tumors that share genetic markers generally absent in c-myc and int-2-initiated tumors.

P. Leder, B. W. Morrison, Briggs W. Morrison, 1994, Oncogene.

MEK1 signaling mediates transformation and metastasis of EpH4 mammary epithelial cells independent of an epithelial to mesenchymal transition.

P. Leder, J. Pinkas, 2002, Cancer research.

The IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation

P. Leder, S. Greenberg, A. Luster, 1995, The Journal of experimental medicine.

Mouse Hus1, a homolog of the Schizosaccharomyces pombe hus1+ cell cycle checkpoint gene.

P. Leder, R. Weiss, T. Enoch, 1999, Genomics.

Mouse ζ- and α-Globin Genes: Embryonic Survival, α-Thalassemia, and Genetic Background Effects

P. Leder, B. Whitney, A. Leder, 1997 .

Active anaphylaxis in IgE-deficient mice

P. Leder, J. Drazen, C. Deng, 1994, Nature.

Mutation of the Murine Bloom's Syndrome Gene Produces Global Genome Destabilization

P. Leder, J. Pinkas, N. Chester, 2006, Molecular and Cellular Biology.

Humoral immune functions in IL-4 transgenic mice.

P. Leder, H. Burstein, A. Abbas, 1991, Journal of immunology.

A mutant immunoglobulin light chain is formed by aberrant DNA- and RNA-splicing events

J. Seidman, P. Leder, Jonathan G. Seidman, 1980, Nature.

Characterization of light chain and light chain constant region fragment mRNAs in MPC 11 mouse myeloma cells and variants

P. Leder, T. Honjo, W. Kuehl, 1975, Cell.

A RIBOSOME-CATALYZED REACTION BETWEEN N-FORMYLMETHIONYL-TRNA AND PUROMYCIN

P. Leder, A. Zamir, D. Elson, 1966, Proceedings of the National Academy of Sciences of the United States of America.

A normal beta-globin allele as a modifier gene ameliorating the severity of alpha-thalassemia in mice.

P. Leder, E. Wiener, S. Wickramasinghe, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Regulation of initiation and elongation factor levels in Escherichia coli as assessed by a quantitative immunoassay.

P. Leder, S. W. Krauss, 1975, The Journal of biological chemistry.

Biosynthesis of phage-specific initiation dipeptides. A purified biosynthetic system derived from Escherichia coli.

P. Leder, D. Roufa, 1971, The Journal of biological chemistry.

Translation of Bacteriophage Qβ Messenger RNA in a Murine Krebs 2 Ascites Tumor Cell-Free System

P. Leder, H. Aviv, I. Boime, 1972, Science.

Translational initiation: defects arising in Escherichia coli infected with phage T7, , and Q .

P. Leder, R. Callahan, L. Skogerson, 1972, Archives of biochemistry and biophysics.

Initiation of protein synthesis. 3. Factor-GTP-codon-dependent binding of F-met-tRNA to ribosomes.

P. Leder, M. Nau, 1967, Proceedings of the National Academy of Sciences of the United States of America.

Disruption of formin-encoding transcripts in two mutant limb deformity alleles

P. Leder, R. Maas, R. Zeller, 1990, Nature.

RNA CODEWORDS AND PROTEIN SYNTHESIS, 3. ON THE NUCLEOTIDE SEQUENCE OF A CYSTEINE AND A LEUCINE RNA CODEWORD.

M. Nirenberg, P. Leder, M W NIRENBERG, 1964, Proceedings of the National Academy of Sciences of the United States of America.

Homologous Genomic Fragments in the Mouse Pre-T Cell Receptor α (pTa) and Xist Loci ☆

P. Leder, Jeannie T. Lee, B. Reizis, 2000 .

The elongation reactions in protein synthesis.

P. Leder, 1973, Advances in protein chemistry.

Regulation of genomic imprinting by gametic and embryonic processes.

P. Leder, J. Chaillet, D. Bader, 1995, Genes & development.

The organization and evolution of cloned globin genes.

P. Leder, D. Hamer, A. Leder, 1981, Progress in clinical and biological research.

Cutaneous lymphoproliferation and lymphomas in interleukin 7 transgenic mice

P. Leder, R. Tepper, R. Moreadith, 1993, The Journal of experimental medicine.

Genome-wide SNP analysis of Tg.AC transgenic mice reveals an oncogenic collaboration between v-Ha-ras and Ink4a, which is absent in p53 deficiency

P. Leder, J. Moran, D. Beier, 2008, Oncogene.

Hus1 Acts Upstream of Chk1 in a Mammalian DNA Damage Response Pathway

S. Elledge, P. Leder, S. Matsuoka, 2002, Current Biology.

Inactivation of mouse Hus1 results in genomic instability and impaired responses to genotoxic stress.

P. Leder, R. Weiss, T. Enoch, 2000, Genes & development.

Brain tumours and lymphomas in transgenic mice that carry HTLV-I LTR/c-myc and Ig/tax genes.

R. Cardiff, P. Leder, N. Benvenisty, 1992, Oncogene.

Bcl-2-mediated cell survival promotes metastasis of EpH4 betaMEKDD mammary epithelial cells.

P. Leder, J. Pinkas, Stuart S. Martin, 2004, Molecular cancer research : MCR.

Keratinocyte growth factor induces mammary and prostatic hyperplasia and mammary adenocarcinoma in transgenic mice.

P. Leder, D. Kitsberg, Kitsberg Di, 1996, Oncogene.

Characteristics of rabbit globin mRNA purification by oligo(dT) cellulose chromatography.

P. Leder, H. Aviv, J. Gielen, 1974, Archives of biochemistry and biophysics.

Translocation of mRNA codons. II. Properties of an anti-translocase antibody.

P. Leder, D. Roufa, L. Skogerson, 1969, Proceedings of the National Academy of Sciences of the United States of America.

An Apoptosis-inducing Isoform of Neu Differentiation Factor (NDF) Identified Using a Novel Screen for Dominant, Apoptosis-inducing Genes

P. Leder, S. Grimm, 1997, The Journal of experimental medicine.

In situ hybridization reveals co-expression of embryonic and adult alpha globin genes in the earliest murine erythrocyte progenitors.

P. Leder, M. Shen, A. Kuo, 1992, Development.

Mouse zeta- and alpha-globin genes: embryonic survival, alpha-thalassemia, and genetic background effects.

P. Leder, B. Whitney, A. Leder, 1997, Blood.

Summary In situ hybridization reveals co-expression of embryonic and adult globin genes in the earliest murine erythrocyte progenitors

P. Leder, M. Shen, A. Kuo, 1999 .

A translocated human c-myc oncogene is altered in a conserved coding sequence.

P. Leder, T. Vasicek, G. Lenoir, 1986, Proceedings of the National Academy of Sciences of the United States of America.

The same genomic region is disrupted in two transgene-induced limb deformity alleles

P. Leder, A. Wynshaw-Boris, T. Vogt, 2004, Mammalian Genome.

Translocation of mRNA codons. I. The preparation and characteristics of a homogeneous enzyme.

P. Leder, M. Nau, L. Skogerson, 1969, Proceedings of the National Academy of Sciences of the United States of America.

A conserved sequence in the immunoglobulin J kappa-C kappa intron: possible enhancer element.

P. Leder, M. Kuehl, E. E. Max, 1983, Nature.

Organization and complete sequence of identical embryonic and plasmacytoma kappa V-region genes.

P. Leder, Y. Nishioka, 1980, The Journal of biological chemistry.

THE ARRANGEMENT, REARRANGEMENT AND ORIGIN OF IMMUNOGLOBULIN GENES

J. Seidman, P. Leder, E. E. Max, 1979 .

Origin of immunoglobulin gene diversity: the evidence and a restriction-modification model.

J. Seidman, P. Leder, T. Honjo, 1977, Cold Spring Harbor symposia on quantitative biology.

Tracing lymphopoiesis with the aid of a pTalpha-controlled reporter gene.

P. Leder, F. Gounari, H. Fehling, 2002, Nature immunology.

IL-4 induces allergic-like inflammatory disease and alters T cell development in transgenic mice

P. Leder, A. Abbas, B. Stanger, 1990, Cell.

DelBank: a mouse ES-cell resource for generating deletions

P. Leder, J. Schimenti, Y. Ishida, 2001, Nature Genetics.

Signal transduction pathways activated and required for mammary carcinogenesis in response to specific oncogenes

P. Leder, L. Amundadottir, 1998, Oncogene.

Immunoglobulin double-isotype expression by trans-mRNA in a human immunoglobulin transgenic mouse.

P. Leder, M. Nussenzweig, T. Honjo, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Constitutive and allergen-induced expression of eotaxin mRNA in the guinea pig lung

P. Leder, J. Drazen, C. Lilly, 1995, The Journal of experimental medicine.

N-FORMYLMETHIONYL-TRNA AND PUROMYCIN

P. Leder, A. Zamir, D. Elson, 2016 .

The Werner Syndrome Gene Product Co-purifies with the DNA Replication Complex and Interacts with PCNA and Topoisomerase I*

P. Leder, Curtis C. Harris, E. Spillare, 1999, The Journal of Biological Chemistry.

Mat-8, a Novel Phospholemman-like Protein Expressed in Human Breast Tumors, Induces a Chloride Conductance in Xenopus Oocytes (*)

P. Leder, Yvonne M. Kobayashi, L. Jones, 1995, The Journal of Biological Chemistry.

Structural analysis of both products of a reciprocal translocation between c-myc and immunoglobulin loci in Burkitt lymphoma.

P. Leder, G. Lenoir, J. Battey, 1985, Nucleic acids research.

Protein synthesis directed by encephalomyocarditis virus RNA. II. The in vitro synthesis of high molecular weight proteins and elements of the viral capsid.

P. Leder, H. Aviv, I. Boime, 1971, Biochemical and biophysical research communications.

MEK 1 Signaling Mediates Transformation and Metastasis of EpH 4 Mammary Epithelial Cells Independent of an Epithelial to Mesenchymal Transition 1

P. Leder, J. Pinkas, 2002 .

The gene for the human mast cell high-affinity IgE receptor alpha chain: chromosomal localization to Iq21-q23 and RFLP analysis.

P. Leder, R. Eddy, T. Shows, 1989, American journal of human genetics.

The gene for the rat mast cell high affinity IgE receptor alpha chain. Structure and alternative mRNA splicing patterns.

P. Leder, A. Shimizu, I. Tepler, 1989, The Journal of biological chemistry.

Human and rat mast cell high-affinity immunoglobulin E receptors : Characterization of putative a-chain gene products ( cDNA cloning / allergy )

P. Benfey, P. Leder, A. Shimizu, 2022 .

The Formins: Connecting Embryonic Pattern Formation and Hypofertility in the Mouse

P. Leder, 2004, Annals of the New York Academy of Sciences.

In vitro synthesis of DNA complementary to mRNA derived from a light chain-producing myeloma tumour.

P. Leder, H. Aviv, J. Ross, 1973, Nature: New biology.

Initiation and protein synthesis: translation of di- and tri-codon messengers.

P. Leder, R. Erbe, 1968, Biochemical and biophysical research communications.

Immunoglobulin light-chain structural gene sequences cloned in a bacterial plasmid

J. Seidman, P. Leder, M. Edgell, 1978, Nature.

Organization of immunoglobulin genes: reiteration frequency of the mouse kappa chain constant region gene.

P. Leder, T. Honjo, M. Nau, 1974, Proceedings of the National Academy of Sciences of the United States of America.

RNA codewords and protein synthesis, 8. Nucleotide sequences of synonym codons for arginine, valine, cysteine, and alanine.

M. Nirenberg, P. Leder, R. Brimacombe, 1965, Proceedings of the National Academy of Sciences of the United States of America.

Identification of a cytoplasmic, phorbol ester-inducible isoform of protein tyrosine phosphatase epsilon.

P. Leder, A. Elson, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Perinatal lethality (ple): a mutation caused by integration of a transgene into distal mouse chromosome 15.

P. Leder, C. Morton, D. Beier, 1989, Genomics.

The Mouse formin (Fmn) Gene: Abundant Circular RNA Transcripts and Gene-Targeted Deletion Analysis

P. Leder, A. Kuo, D. Chan, 1998, Molecular medicine.

Formin1 disruption confers oligodactylism and alters Bmp signaling.

P. Leder, A. Zuniga, Fen Zhou, 2009, Human molecular genetics.

The RNA code: Nature’s Rosetta Stone

P. Leder, C. Caskey, 2014, Proceedings of the National Academy of Sciences.

Protein biosynthesis in Escherichia coli. Purification and characteristics of a mutant G factor.

P. Leder, A. Bernardi, 1970, The Journal of biological chemistry.

Formin 1-Isoform IV Deficient Cells Exhibit Defects in Cell Spreading and Focal Adhesion Formation

P. Leder, Fen Zhou, M. Dettenhofer, 2008, PloS one.

The mouse formin (Fmn) gene: genomic structure, novel exons, and genetic mapping.

P. Leder, D. Chan, C. C. Wang, 1997, Genomics.

A variant limb deformity transcript expressed in the embryonic mouse limb defines a novel formin.

P. Leder, A. Kuo, L. Jackson-Grusby, 1992, Genes & development.

The cloning of mouse globin and surrounding gene sequences in bacteriophage lambda.

J. Seidman, P. Leder, M. Edgell, 1978, Cold Spring Harbor symposia on quantitative biology.

DNA complementary to globin and immunoglobulin mRNA: a probe to study gene expression.

P. Leder, H. Aviv, J. Ross, 1974, Advances in Experimental Medicine and Biology.

neu protooncogene fused to an immunoglobulin heavy chain gene requires immunoglobulin light chain for cell surface expression and oncogenic transformation.

P. Leder, J. Flanagan, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Erythropoiesis in the mouse begins with the production of a distinct population of red blood cells in the blood islands of the visceral yolk sac at day

P. Leder, M. Shen, A. Kuo, 1999 .

Characterization of the initial peptide of Q-beta RNA polymerase and control of its synthesis.

P. Leder, D. Roufa, L. Skogerson, 1971, Proceedings of the National Academy of Sciences of the United States of America.

WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the proline glycine and methionine-rich motif.

P. Leder, R. Reed, R. Reed, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Formin binding proteins bear WWP/WW domains that bind proline‐rich peptides and functionally resemble SH3 domains.

P. Leder, M. Bedford, D. Chan, 1996, The EMBO journal.

Translation: its mechanism and control.

D. Schlessinger, P. Leder, K. Moldave, 1972, Science.

RNA CODEWORDS AND PROTEIN SYNTHESIS. II. NUCLEOTIDE SEQUENCE OF A VALINE RNA CODEWORD.

M. Nirenberg, P. Leder, M NIRENBERG, 1964, Proceedings of the National Academy of Sciences of the United States of America.

Identifying genes preferentially expressed in undifferentiated embryonic stem cells

P. Leder, Xiajun Li, 2007, BMC Cell Biology.

RNA CODEWORDS AND PROTEIN SYNTHESIS, VI. ON THE NUCLEOTIDE SEQUENCES OF DEGENERATE CODEWORD SETS FOR ISOLEUCINE, TYROSINE, ASPARAGINE, AND LYSINE.

M. Nirenberg, P. Leder, R. Brimacombe, 1965, Proceedings of the National Academy of Sciences of the United States of America.

Duplication and deletion in the human immunoglobulin epsilon genes.

P. Leder, E. E. Max, I. Kirsch, 1982, Cell.

A normal b-globin allele as a modifier gene ameliorating the severity of a-thalassemia in mice

Lee, J., Wickramasinghe, 1999 .

Effect of the interval between irradiation and conception on mutation frequency in female mice.

P. Leder, E. Ohtsuka, F. Rottman, 1965, Proceedings of the National Academy of Sciences of the United States of America.

Targeted Disruption of the Chemokine Eotaxin Partially Reduces Antigen-induced Tissue Eosinophilia

P. Leder, A. Luster, E. Pearlman, 1997, The Journal of experimental medicine.

Expression of Brcal is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice

P. Leder, C. Kozak, T. Lane, 2007 .

F16, a Mitochondriotoxic Compound, Triggers Apoptosis or Necrosis Depending on the Genetic Background of the Target Carcinoma Cell

P. Leder, V. Fantin, 2004, Cancer Research.

Enzymatic synthesis of solid phase-bound DNA sequences corresponding to specific mammalian genes.

P. Leder, P. Venetiáner, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Normal human B cells display ordered light chain gene rearrangements and deletions

T. Waldmann, S. Korsmeyer, P. Leder, 1982, The Journal of experimental medicine.

The Mouse formin (Fmn) Gene: Abundant Circular RNA Transcripts and Gene-Targeted Deletion Analysis

P. Leder, A. Kuo, D. Chan, 1998, Molecular medicine.

The Bloom's syndrome helicase is critical for development and function of the alphabeta T-cell lineage.

P. Leder, B. Reizis, N. Chester, 2007, Molecular and cellular biology.