Jian Zhang

发表

The Structural Basis of ATP as an Allosteric Modulator

Shuai Li, Qi Wang, Ruth Nussinov, 2014, PLoS Comput. Biol..

Harnessing Allostery: A Novel Approach to Drug Discovery

Shaoyong Lu, Shuai Li, Jian Zhang, 2014, Medicinal research reviews.

Conformational Transition Pathway in the Activation Process of Allosteric Glucokinase

Shaoyong Lu, Jian Zhang, Ting Shi, 2013, PloS one.

Allosteric Modulator Discovery: From Serendipity to Structure-Based Design.

Shaoyong Lu, Jian Zhang, Xinheng He, 2019, Journal of medicinal chemistry.

Protein Allostery in Drug Discovery

R. Nussinov, Jian Zhang, 2019, Advances in Experimental Medicine and Biology.

Characteristics of Allosteric Proteins, Sites, and Modulators.

Shaoyong Lu, Jian Zhang, Xinheng He, 2019, Advances in experimental medicine and biology.

A novel allosteric site in casein kinase 2α discovered using combining bioinformatics and biochemistry methods

Wenkang Huang, Jian Zhang, Haiming Jiang, 2017, Acta Pharmacologica Sinica.

Inhibitors of Ras–SOS Interactions

Ruth Nussinov, Shaoyong Lu, Jian Zhang, 2016, ChemMedChem.

Drugging Ras GTPase: a comprehensive mechanistic and signaling structural view.

Ruth Nussinov, Shaoyong Lu, Jian Zhang, 2016, Chemical Society reviews.

Allosteric modulators of MEK1: drug design and discovery

Shaoyong Lu, Jian Zhang, Yong-Jun Jiang, 2016, Chemical biology & drug design.

Ras Conformational Ensembles, Allostery, and Signaling.

Ozlem Keskin, Ruth Nussinov, Shaoyong Lu, 2016, Chemical reviews.

Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration.

Shaoyong Lu, Jian Zhang, Haiming Jiang, 2017, Nature chemical biology.

The deacetylase SIRT6 promotes the repair of UV-induced DNA damage by targeting DDB2

Jian Zhang, L. Lan, Anke Geng, 2020, Nucleic acids research.

Discovery of hidden allosteric sites as novel targets for allosteric drug design.

Shaoyong Lu, Jian Zhang, D. Ni, 2017, Drug discovery today.

Phenotype and target-based chemical biology investigations in cancers

Jian Zhang, Guoqiang Chen, Ying Xu, 2018, National science review.

Toward understanding the molecular basis for chemical allosteric modulator design.

Qi Wang, Jian Zhang, Ting Shi, 2012, Journal of Molecular Graphics and Modelling.

Improved Method for the Identification and Validation of Allosteric Sites

Shaoyong Lu, Wenkang Huang, Qiancheng Shen, 2017, J. Chem. Inf. Model..

Prediction of Human Clearance Based on Animal Data and Molecular Properties

W. Liu, Shaoyong Lu, Wenkang Huang, 2015, Chemical biology & drug design.

Proteome-Scale Investigation of Protein Allosteric Regulation Perturbed by Somatic Mutations in 7,000 Cancer Genomes.

Zhongming Zhao, Qiancheng Shen, Jian Zhang, 2017, American journal of human genetics.

HEMD: An Integrated Tool of Human Epigenetic Enzymes and Chemical Modulators for Therapeutics

Wenkang Huang, Qi Wang, Jian Zhang, 2012, PloS one.

Recent computational advances in the identification of allosteric sites in proteins.

Shaoyong Lu, Jian Zhang, Wenkang Huang, 2014, Drug discovery today.

Unraveling allosteric landscapes of allosterome with ASD

Shaoyong Lu, Qi Wang, Qiancheng Shen, 2019, Nucleic Acids Res..

Single Binding Pockets Versus Allosteric Binding.

Jian Zhang, K. Song, 2018, Methods in molecular biology.

Intrinsic protein disorder in oncogenic KRAS signaling

Ruth Nussinov, Jian Zhang, Hyunbum Jang, 2017, Cellular and Molecular Life Sciences.

Molecular Dynamics Simulations and Dynamic Network Analysis Reveal the Allosteric Unbinding of Monobody to H-Ras Triggered by R135K Mutation

Shaoyong Lu, Jian Zhang, D. Ni, 2017, International journal of molecular sciences.

Computational Insights into the Interactions between Calmodulin and the c/nSH2 Domains of p85α Regulatory Subunit of PI3Kα: Implication for PI3Kα Activation by Calmodulin

Shaoyong Lu, Jian Zhang, D. Ni, 2018, International journal of molecular sciences.

Methods Applied for the Allosteric Site Revelation

Shaoyong Lu, Jian Zhang, D. Ni, 2018, Encyclopedia of Analytical Chemistry.

Raf-1 Cysteine-Rich Domain Increases the Affinity of K-Ras/Raf at the Membrane, Promoting MAPK Signaling.

Ruth Nussinov, Jian Zhang, Hyunbum Jang, 2018, Structure.

How Parkinson's disease-related mutations disrupt the dimerization of WD40 domain in LRRK2: a comparative molecular dynamics simulation study.

Shaoyong Lu, Jian Zhang, Xinyi Li, 2020, Physical chemistry chemical physics : PCCP.

Identification of a natural inhibitor of methionine adenosyltransferase 2A regulating one-carbon metabolism in keratinocytes

Shaoyong Lu, Jian Zhang, Hong Wang, 2018, EBioMedicine.

AlloDriver: a method for the identification and analysis of cancer driver targets

Shaoyong Lu, Qiancheng Shen, Jian Zhang, 2019, Nucleic Acids Res..

Calmodulin and PI3K Signaling in KRAS Cancers.

Ruth Nussinov, Shaoyong Lu, Jian Zhang, 2017, Trends in cancer.

Zinc-mediated conformational preselection mechanism in the allosteric control of DNA binding to the zinc transcriptional regulator (ZitR)

Shaoyong Lu, Jian Zhang, Xinheng He, 2020, Scientific Reports.

The Mechanism of Allosteric Inhibition of Protein Tyrosine Phosphatase 1B

Shaoyong Lu, Wenkang Huang, Qiancheng Shen, 2014, PloS one.

Reply to: Binding site for MDL-801 on SIRT6

Shaoyong Lu, Jian Zhang, Yingyi Chen, 2021, Nature Chemical Biology.

Discovery of cryptic allosteric sites using reversed allosteric communication by a combined computational and experimental strategy

Shaoyong Lu, Jian Zhang, Xinheng He, 2020, Chemical science.

Identification of a cellularly active SIRT6 allosteric activator

Shaoyong Lu, Jian Zhang, Yingyi Chen, 2018, Nature Chemical Biology.

Metabolic intermediate acetyl phosphate modulates bacterial virulence via acetylation

Shaoyong Lu, Jian Zhang, Guo-Ping Zhao, 2019, Emerging microbes & infections.

Small Molecule Allosteric Modulators of G-Protein-Coupled Receptors: Drug-Target Interactions.

Shaoyong Lu, Jian Zhang, 2018, Journal of medicinal chemistry.

Computational methods-guided design of modulators targeting protein-protein interactions (PPIs).

Shaoyong Lu, Jian Zhang, Xinheng He, 2020, European journal of medicinal chemistry.

Combining Allosteric and Orthosteric Drugs to Overcome Drug Resistance.

Shaoyong Lu, Jian Zhang, D. Ni, 2020, Trends in pharmacological sciences.

Emergence of allosteric drug-resistance mutations: new challenges for allosteric drug discovery.

Shaoyong Lu, Jian Zhang, Xinheng He, 2019, Drug discovery today.

Designed covalent allosteric modulators: an emerging paradigm in drug discovery.

Shaoyong Lu, Jian Zhang, 2017, Drug discovery today.

Identification of Novel Compounds for Human Bitter Taste Receptors

Wenkang Huang, Jian Zhang, Yingyi Chen, 2014, Chemical biology & drug design.

Allosteric binding sites at the receptor-lipid bilayer interface: novel targets for GPCR drug discovery.

Shaoyong Lu, Jian Zhang, Ying Wang, 2020, Drug discovery today.

Deactivation Pathway of Ras GTPase Underlies Conformational Substates as Targets for Drug Design

Shaoyong Lu, Jian Zhang, Xinheng He, 2019, ACS Catalysis.

Mechanism of allosteric activation of SIRT6 revealed by the action of rationally designed activators

Shaoyong Lu, Jian Zhang, Yingyi Chen, 2020, Acta pharmaceutica Sinica. B.

Reversible lysine acetylation is involved in DNA replication initiation by regulating activities of initiator DnaA in Escherichia coli

Shuai Li, Jian Zhang, Guoping Zhao, 2016, Scientific Reports.

Suramin and NF449 are IP5K inhibitors that disrupt inositol hexakisphosphate–mediated regulation of cullin–RING ligase and sensitize cancer cells to MLN4924/pevonedistat

Jian Zhang, Xiuyan Yang, Feng Rao, 2020, The Journal of Biological Chemistry.

Screening and biological evaluation of a novel STAT3 signaling pathway inhibitor against cancer.

Jian Zhang, Min Huang, Jianrong Xu, 2016, Bioorganic & medicinal chemistry letters.

New Insights into PI3K Inhibitor Design using X-ray Structures of PI3Kα Complexed with a Potent Lead Compound

Jian Zhang, K. Song, Xiuyan Yang, 2017, Scientific Reports.

SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation

Jian Zhang, Xinyi Liu, A. Orian, 2015, Protein & Cell.

Unraveling the Role of Arg4 and Arg6 in the Auto‐Inhibition Mechanism of GSK3β From Molecular Dynamics Simulation

Shaoyong Lu, Qiancheng Shen, Shuai Li, 2014, Chemical biology & drug design.

Interaction of Calmodulin with the cSH2 Domain of the p85 Regulatory Subunit.

R. Nussinov, Shaoyong Lu, Jian Zhang, 2018, Biochemistry.

Rational design of a sensitivity-enhanced tracer for discovering efficient APC–Asef inhibitors

Shaoyong Lu, Jian Zhang, K. Song, 2022, Nature Communications.

Markov State Models and Molecular Dynamics Simulations Reveal the Conformational Transition of the Intrinsically Disordered Hypervariable Region of K-Ras4B to the Ordered Conformation

R. Nussinov, Shaoyong Lu, Jian Zhang, 2022, J. Chem. Inf. Model..

Design, synthesis, and biological evaluation of thieno[3,2‐d]pyrimidine derivatives as potential simplified phosphatidylinositol 3‐kinase alpha inhibitors

Jian Zhang, K. Song, Xiuyan Yang, 2019, Chemical biology & drug design.

How calcium inhibits the magnesium‐dependent kinase gsk3β: A molecular simulation study

Shaoyong Lu, Wenkang Huang, Jian Zhang, 2013, Proteins.

Intrinsic protein disorder in oncogenic KRAS signaling

R. Nussinov, Shuai Li, Jian Zhang, 2017, Cellular and Molecular Life Sciences.

The SIRT6 activator MDL‐800 improves genomic stability and pluripotency of old murine‐derived iPS cells

Jian Zhang, Shaorong Gao, Zhen Qian, 2020, Aging cell.

Crucial role of copper in detection of metal-coordinating odorants

Zhimin Huang, Jian Zhang, Xubo Su, 2012, Proceedings of the National Academy of Sciences.

Atomic-scale insights into allosteric inhibition and evolutional rescue mechanism of Streptococcus thermophilus Cas9 by the anti-CRISPR protein AcrIIA6

Shaoyong Lu, Jian Zhang, D. Ni, 2021, Computational and structural biotechnology journal.

Calmodulin (CaM) Activates PI3Kα by Targeting the "Soft" CaM-Binding Motifs in Both the nSH2 and cSH2 Domains of p85α.

R. Nussinov, Jian Zhang, Mingzhen Zhang, 2018, The journal of physical chemistry. B.

BitterX: a tool for understanding bitter taste in humans

Shaoyong Lu, Jian Zhang, Qiancheng Shen, 2016, Scientific Reports.

Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an ERK-FBXO22-BAG3 axis in tumorigenesis

Jian Zhang, Min Huang, D. Ni, 2021, Cell Death & Differentiation.

The chemical diversity and structure-based discovery of allosteric modulators for the PIF-pocket of protein kinase PDK1

Shaoyong Lu, Jian Zhang, Yingyi Chen, 2019, Journal of enzyme inhibition and medicinal chemistry.

Along the allostery stream: Recent advances in computational methods for allosteric drug discovery

Shaoyong Lu, Jian Zhang, D. Ni, 2021, WIREs Computational Molecular Science.

SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways.

Jian Zhang, J. Qin, K. Song, 2020, Cancer cell.

GTP Binding and Oncogenic Mutations May Attenuate Hypervariable Region (HVR)-Catalytic Domain Interactions in Small GTPase K-Ras4B, Exposing the Effector Binding Site*

Ruth Nussinov, Shaoyong Lu, Hyunbum Jang, 2015, The Journal of Biological Chemistry.

ORDB, HORDE, ODORactor and other on-line knowledge resources of olfactory receptor-odorant interactions

Tsviya Olender, Doron Lancet, Rixin Wang, 2016, Database J. Biol. Databases Curation.

Targeting RAS phosphorylation in cancer therapy: Mechanisms and modulators

Shaoyong Lu, Jian Zhang, D. Ni, 2021, Acta pharmaceutica Sinica. B.

Drugging K-RasG12C through covalent inhibitors: Mission possible?

Shaoyong Lu, Jian Zhang, Xinheng He, 2019, Pharmacology & therapeutics.

Mechanistic insights into the effect of phosphorylation on Ras conformational dynamics and its interactions with cell signaling proteins

Shaoyong Lu, Jian Zhang, D. Ni, 2021, Computational and structural biotechnology journal.

The Structural Basis of Oncogenic Mutations G12, G13 and Q61 in Small GTPase K-Ras4B

Ruth Nussinov, Shaoyong Lu, Hyunbum Jang, 2016, Scientific Reports.

Emerging roles of allosteric modulators in the regulation of protein‐protein interactions (PPIs): A new paradigm for PPI drug discovery

Shaoyong Lu, Duan Ni, Jian Zhang, 2019, Medicinal research reviews.

Germline Mutations in CDH23, Encoding Cadherin-Related 23, Are Associated with Both Familial and Sporadic Pituitary Adenomas.

Shaoyong Lu, Jian Zhang, Hai Yan, 2017, American journal of human genetics.

AlloFinder: a strategy for allosteric modulator discovery and allosterome analyses

Jianrong Xu, Min Huang, Shaoyong Lu, 2018, Nucleic Acids Res..

Small-molecule activating SIRT6 elicits therapeutic effects and synergistically promotes anti-tumor activity of vitamin D3 in colorectal cancer

Jian Zhang, Yingyi Chen, K. Song, 2020, Theranostics.

Structure of an inactive conformation of GTP-bound RhoA GTPase.

Shaoyong Lu, Jian Zhang, Yi Zheng, 2021, Structure.

The higher level of complexity of K‐Ras4B activation at the membrane

Ruth Nussinov, Shaoyong Lu, Jian Zhang, 2016, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Insights into the Role of Magnesium Triad in myo-Inositol Monophosphatase: Metal Mechanism, Substrate Binding, and Lithium Therapy

Xiaobai Li, Yingyi Chen, Xinyi Liu, 2012, J. Chem. Inf. Model..

Acetylation of calmodulin regulates synaptic plasticity and fear learning

Jian Zhang, D. Ni, Hai-Long Zhang, 2021, The Journal of biological chemistry.

Mechanism of zinc ejection by disulfiram in nonstructural protein 5A.

Shaoyong Lu, Jian Zhang, D. Ni, 2021, Physical chemistry chemical physics : PCCP.

Discovery of novel nonpeptide allosteric inhibitors interrupting the interaction of CDK2/cyclin A3 by virtual screening and bioassays.

Shuai Li, Jian Zhang, Lv Geng, 2015, Bioorganic & medicinal chemistry letters.

Novel TBX1 loss-of-function mutation causes isolated conotruncal heart defects in Chinese patients without 22q11.2 deletion

Jian Zhang, Jian Wang, K. Sun, 2014, BMC Medical Genetics.

SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation

Jian Zhang, Xinyi Liu, A. Orian, 2015, Protein & Cell.

ODORactor: a web server for deciphering olfactory coding

Zhen Li, Yi Pan, Qi Wang, 2011, Bioinform..

Allosteric inhibitors of the STAT3 signaling pathway.

Jian Zhang, Da Jia, Xiao-Fei Shen, 2020, European journal of medicinal chemistry.

Selective Covalent Targeting of Pyruvate Kinase M2 Using Arsenous Warheads.

Jian Zhang, Xiaoxu Tian, Xinheng He, 2023, Journal of medicinal chemistry.

Small-molecule inhibitor targeting the Hsp90-Cdc37 protein-protein interaction in colorectal cancer

Jian Zhang, Li Li, Lei Wang, 2019, Science Advances.

Novel inhibitor against Malassezia globosa LIP1 (SMG1), a potential anti-dandruff target.

Jian Zhang, Yonghua Wang, Shaohua Guo, 2015, Bioorganic & medicinal chemistry letters.

Computational elucidation of allosteric communication in proteins for allosteric drug design.

Shaoyong Lu, Jian Zhang, D. Ni, 2022, Drug discovery today.

Explaining and Predicting Allostery with Allosteric Database and Modern Analytical Techniques.

Shaoyong Lu, Jian Zhang, R. Kong, 2022, Journal of molecular biology.

Harnessing Reversed Allosteric Communication: A Novel Strategy for Allosteric Drug Discovery.

Shaoyong Lu, Jian Zhang, D. Ni, 2021, Journal of medicinal chemistry.

Insight into the mechanism of allosteric activation of PI3Kα by oncoprotein K-Ras4B.

Shaoyong Lu, Jian Zhang, Xinheng He, 2019, International journal of biological macromolecules.

Allosteric Methods and Their Applications: Facilitating the Discovery of Allosteric Drugs and the Investigation of Allosteric Mechanisms.

Shaoyong Lu, Qiancheng Shen, Jian Zhang, 2019, Accounts of chemical research.

Are the Apo Proteins Suitable for the Rational Discovery of Allosteric Drugs?

Shaoyong Lu, Jian Zhang, Kun Song, 2018, J. Chem. Inf. Model..

Progress in Allosteric Database.

Shaoyong Lu, Kun Song, Jian Zhang, 2019, Advances in experimental medicine and biology.

ASD v3.0: unraveling allosteric regulation with structural mechanisms and biological networks

Shuai Li, Shaoyong Lu, Jian Zhang, 2015, Nucleic Acids Res..

The Mechanism of ATP-Dependent Allosteric Protection of Akt Kinase Phosphorylation.

Ruth Nussinov, Shaoyong Lu, Rong Deng, 2015, Structure.

ASBench: benchmarking sets for allosteric discovery

Shaoyong Lu, Jian Zhang, Wenkang Huang, 2015, Bioinform..

Computational Tools for Allosteric Drug Discovery: Site Identification and Focus Library Design.

Ruth Nussinov, Jian Zhang, Wenkang Huang, 2017, Methods in molecular biology.

Delineating the activation mechanism and conformational landscape of a class B G protein-coupled receptor glucagon receptor

Shaoyong Lu, Jian Zhang, R. Kong, 2022, Computational and structural biotechnology journal.

oward an understanding of the sequence and structural basis of allosteric roteins

Shaoyong Lu, Ting Shi, Jian Zhang, 2013 .

ASD: a comprehensive database of allosteric proteins and modulators

Geng Wu, Qi Wang, Haifeng Chen, 2010, Nucleic Acids Res..

ASD v2.0: updated content and novel features focusing on allosteric regulation

Shuai Li, Shaoyong Lu, Jian Zhang, 2013, Nucleic Acids Res..

SPPS: A Sequence-Based Method for Predicting Probability of Protein-Protein Interaction Partners

Bin Liu, Jian Zhang, Ting Shi, 2012, PloS one.

Exploring the Desumoylation Process of SENP1: A Study Combined MD Simulations with QM/MM Calculations on SENP1-SUMO1-RanGAP1

Yanlong Zhao, Shaoyong Lu, Jian Zhang, 2013, J. Chem. Inf. Model..

IDDB: a comprehensive resource featuring genes, variants and characteristics associated with infertility

Jian Zhang, Danjun Li, Ashfaq Ur Rehman, 2020, Nucleic Acids Res..

Advances and Insights of APC-Asef Inhibitors for Metastatic Colorectal Cancer Therapy

Shaoyong Lu, Jian Zhang, Xiuyan Yang, 2021, Frontiers in Molecular Biosciences.

Hidden allosteric sites and De-Novo drug design

Shaoyong Lu, Jian Zhang, A. Rehman, 2021, Expert opinion on drug discovery.

Mechanism for the autophosphorylation of CheA histidine kinase: QM/MM calculations.

Jian Zhang, Ting Shi, Hualiang Jiang, 2011, The journal of physical chemistry. B.

Conformational Selection Mechanism Provides Structural Insights into the Optimization of APC-Asef Inhibitors

Shaoyong Lu, Jian Zhang, Xinheng He, 2021, Molecules.

Allosite: a method for predicting allosteric sites

Yu Luo, Yanlong Zhao, Tingjun Hou, 2013, Bioinform..

Multi‐Arm PEG/Peptidomimetic Conjugate Inhibitors of DR6/APP Interaction Block Hematogenous Tumor Cell Extravasation

Jian Zhang, Y. Duan, Xupeng Yang, 2021, Advanced science.

Targeting a cryptic allosteric site of SIRT6 with small-molecule inhibitors that inhibit the migration of pancreatic cancer cells

Shaoyong Lu, Jian Zhang, Yingyi Chen, 2021, Acta pharmaceutica Sinica. B.

AlloReverse: multiscale understanding among hierarchical allosteric regulations

Shaoyong Lu, Jian Zhang, Xinyi Liu, 2023, Nucleic acids research.

Spatiotemporal and global profiling of DNA–protein interactions enables discovery of low-affinity transcription factors

Jian Zhang, Ke Yan, Minjia Tan, 2023, Nature Chemistry.

A Computational Method to Predict Effects of Residue Mutations on the Catalytic Efficiency of Hydrolases

Shaoyong Lu, Jian Zhang, K. Song, 2021, Catalysts.

Use of the XRCC2 promoter for in vivo cancer diagnosis and therapy

Jian Zhang, Huanyin Tang, Zhu Xu, 2018, Cell Death & Disease.

DeepAlloDriver: a deep learning-based strategy to predict cancer driver mutations

Jian Zhang, Xinyi Liu, K. Song, 2023, Nucleic Acids Res..

Proteome-Scale Investigation of Protein Allosteric Regulation Perturbed by Somatic Mutations in 7,000 Cancer Genomes.

Qiancheng Shen, Jian Zhang, F. Cheng, 2017, American Journal of Human Genetics.

Toward an understanding of the sequence and structural basis of allosteric proteins.

Shaoyong Lu, Qi Wang, Jian Zhang, 2013, Journal of molecular graphics & modelling.

Designed covalent allosteric modulators: an emerging paradigm in drug discovery.

Shaoyong Lu, Jian Zhang, 2017, Drug discovery today.

Identification of a natural inhibitor of methionine adenosyltransferase 2A regulating one-carbon metabolism in keratinocytes

Shaoyong Lu, Jian Zhang, Hong Wang, 2018, EBioMedicine.

ASD2023: towards the integrating landscapes of allosteric knowledgebase.

Shaoyong Lu, Jian Zhang, Xinyi Liu, 2023, Nucleic acids research.

Progressive computational approaches to facilitate decryption of allosteric mechanism and drug discovery.

Shaoyong Lu, Jian Zhang, Xiaobing Lan, 2023, Current opinion in structural biology.

Allosteric Modulator Discovery: From Serendipity to Structure-Based Design.

Shaoyong Lu, Jian Zhang, Xinheng He, 2019, Journal of medicinal chemistry.

How calcium inhibits the magnesium‐dependent kinase gsk3β: A molecular simulation study

Shaoyong Lu, Jian Zhang, Ting Shi, 2013, Proteins: Structure, Function, and Bioinformatics.

Alloscore: a method for predicting allosteric ligand-protein interactions

Shuai Li, Shaoyong Lu, Jian Zhang, 2016, Bioinform..

Rational Design and Structure Validation of a Novel Peptide Inhibitor of the Adenomatous-Polyposis-Coli (APC)-Rho-Guanine-Nucleotide-Exchange-Factor-4 (Asef) Interaction.

Jian Zhang, K. Song, Xiuyan Yang, 2018, Journal of medicinal chemistry.