M. Mansour

发表

Activation of human liver glycogen phosphorylase by alteration of the secondary structure and packing of the catalytic core.

V. L. Rath, M. Ammirati, P. Lemotte, 2000, Molecular cell.

Anilinoquinazoline inhibitors of fructose 1,6-bisphosphatase bind at a novel allosteric site: synthesis, in vitro characterization, and X-ray crystallography.

M. Mansour, D. Danley, G. Schulte, 2002, Journal of medicinal chemistry.

Discovery and optimization of a novel spiropyrrolidine inhibitor of β-secretase (BACE1) through fragment-based drug design.

M. Mansour, J. Pandit, BinQing Wei, 2012, Journal of medicinal chemistry.

3-(2-carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acid: an allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site.

M. Mansour, D. Danley, G. Schulte, 2003, Bioorganic & medicinal chemistry letters.

Theoretical and experimental design of atypical kinase inhibitors: application to p38 MAP kinase.

Dennis E Danley, P. Lemotte, M. Mansour, 2005, Journal of medicinal chemistry.

Small-molecule phosphodiesterase probes: discovery of potent and selective CNS-penetrable quinazoline inhibitors of PDE1

M. Mansour, J. Pandit, F. Menniti, 2014 .

Discovery, SAR, and pharmacokinetics of a novel 3-hydroxyquinolin-2(1H)-one series of potent D-amino acid oxidase (DAAO) inhibitors.

M. Mansour, S. Sakya, K. Borzilleri, 2009, Journal of medicinal chemistry.

Design of selective, ATP-competitive inhibitors of Akt.

Tracey Clark, Matthew Marx, Blaise Lippa, 2010, Journal of medicinal chemistry.

Structural basis for the catalytic mechanism of human phosphodiesterase 9

P. Lemotte, M. Mansour, D. Danley, 2008, Proceedings of the National Academy of Sciences.

Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia

Xiayang Qiu, Dennis E Danley, S. Shenolikar, 2007, Nature Structural &Molecular Biology.

Cloning and Functional Characterization of an NAD+-Dependent DNA Ligase from Staphylococcus aureus

M. Mansour, D. Danley, T. Gootz, 2001, Journal of Bacteriology.

Inhibition of MMP-1 and MMP-13 with phosphinic acids that exploit binding in the S2 pocket.

M. Mansour, D. Danley, G. Schulte, 1999, Bioorganic & medicinal chemistry letters.