D. Danley

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Activation of human liver glycogen phosphorylase by alteration of the secondary structure and packing of the catalytic core.

V. L. Rath, M. Ammirati, P. Lemotte, 2000, Molecular cell.

Anilinoquinazoline inhibitors of fructose 1,6-bisphosphatase bind at a novel allosteric site: synthesis, in vitro characterization, and X-ray crystallography.

M. Mansour, D. Danley, G. Schulte, 2002, Journal of medicinal chemistry.

Identification, Characterization, and Crystal Structure of the Omega Class Glutathione Transferases*

G Chelvanayagam, G. Chelvanayagam, D. Danley, 2000, The Journal of Biological Chemistry.

X-ray analyses of peptide–inhibitor complexes define the structural basis of specificity for human and mouse renins

T. L. Blundell, V. Dhanaraj, H. P. C. Driessen, 1992, Nature.

The 3-D structure of HIV-1 proteinase and the design of antiviral agents for the treatment of AIDS.

T L Blundell, P J Whittle, T. Blundell, 1990, Trends in biochemical sciences.

The 2.0 Å crystal structure of the ERα ligand‐binding domain complexed with lasofoxifene

M. Ammirati, P. Lemotte, D. Danley, 2007, Protein science : a publication of the Protein Society.

3-(2-carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acid: an allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site.

M. Mansour, D. Danley, G. Schulte, 2003, Bioorganic & medicinal chemistry letters.

Crystallizable HIV-1 protease derived from expression of the viral pol gene in Escherichia coli.

D. Danley, P. Hobart, K. Geoghegan, 1989, Biochemical and biophysical research communications.

Structure and mechanism of formation of recombinant-derived chymosin C.

D. Danley, K. Geoghegan, 1988, Journal of Biological Chemistry.

The small GTPase Cdc42 initiates an apoptotic signaling pathway in Jurkat T lymphocytes.

D. Danley, K. Hahn, G. Bokoch, 1997, Molecular biology of the cell.

Glycylcyclines bind to the high-affinity tetracycline ribosomal binding site and evade Tet(M)- and Tet(O)-mediated ribosomal protection

M. Ammirati, D. Danley, L. James, 1996, Antimicrobial agents and chemotherapy.

Extended half-life and elevated steady-state level of a single-chain Fv intrabody are critical for specific intracellular retargeting of its antigen, caspase-7.

D. Danley, W. Marasco, J. Huston, 1999, Journal of immunological methods.

Truncation of human squalene synthase yields active, crystallizable protein.

D. Danley, J. F. Thompson, H. J. Harwood, 1998, Archives of biochemistry and biophysics.

Codominant translational mutants of Chinese hamster ovary cells selected with diphtheria toxin

D. Danley, T. Moehring, J. Moehring, 1979, Somatic cell genetics.

Defective Rho GTPase regulation by IL-1 beta-converting enzyme-mediated cleavage of D4 GDP dissociation inhibitor.

D. Danley, G. Bokoch, T. Chuang, 1996, Journal of immunology.

Posttranslational modification of elongation factor 2 in diphtheria-toxin-resistant mutants of CHO-K1 cells.

D. Danley, T. Moehring, J. Moehring, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Discovery and structural characterization of an allosteric inhibitor of bacterial cis‐prenyltransferase

K. Fennell, D. Danley, B. Chrunyk, 2015, Protein Science.

Role of protein subunits in Proteus rettgeri penicillin G acylase

D. Danley, A. Mccoll, G. Daumy, 1985, Journal of bacteriology.

Crystal Structure of Human Squalene Synthase

D. Danley, G. Schulte, J. Pandit, 2000, The Journal of Biological Chemistry.

Plasminogen Activator Inhibitor-1

E. Goldsmith, D. Danley, J. Mottonen, 2003 .

Experimental evolution of penicillin G acylases from Escherichia coli and Proteus rettgeri

D. Danley, A. Mccoll, G. Daumy, 1985, Journal of bacteriology.

Potent, selective spiropyrrolidine pyrimidinetrione inhibitors of MMP-13.

D. Danley, J. Pandit, E. Laird, 2007, Bioorganic & medicinal chemistry letters.

Rational design, synthesis, and X-ray structure of renin inhibitors with extended P1 sidechains

M. Ammirati, D. Danley, G. Schulte, 1995 .

(3R,4S)-4-(2,4,5-Trifluorophenyl)-pyrrolidin-3-ylamine inhibitors of dipeptidyl peptidase IV: synthesis, in vitro, in vivo, and X-ray crystallographic characterization.

Zhengrong Zhao, Dennis E Danley, M. Ammirati, 2007, Bioorganic & medicinal chemistry letters.

Theoretical and experimental design of atypical kinase inhibitors: application to p38 MAP kinase.

Dennis E Danley, P. Lemotte, M. Mansour, 2005, Journal of medicinal chemistry.

cis-2,5-dicyanopyrrolidine inhibitors of dipeptidyl peptidase IV: synthesis and in vitro, in vivo, and X-ray crystallographic characterization.

M. Ammirati, D. Danley, S. Wright, 2006, Journal of medicinal chemistry.

Synthesis and biological activity of selective pipecolic acid-based TNF-alpha converting enzyme (TACE) inhibitors.

Dennis E Danley, D. Danley, G. Schulte, 2002, Bioorganic & medicinal chemistry letters.

Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules

Ing-Kae Wang, Xiayang Qiu, Dennis E Danley, 2007, Nature Structural &Molecular Biology.

Discovery of a human liver glycogen phosphorylase inhibitor that lowers blood glucose in vivo.

D. Danley, R. McPherson, J. Treadway, 1998, Proceedings of the National Academy of Sciences of the United States of America.

(3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrrolidin-2-yl]-methanone: a potent, selective, orally active dipeptidyl peptidase IV inhibitor.

M. Ammirati, D. Danley, R. McPherson, 2009, Bioorganic & medicinal chemistry letters.

Isolation and characterization of biologically active murine interleukin-6 produced in Escherichia coli.

D. Danley, I. Otterness, L. James, 1991, Gene.

D4-GDI, a Substrate of CPP32, Is Proteolyzed during Fas-induced Apoptosis (*)

D. Danley, G. Bokoch, J. Hanke, 1996, The Journal of Biological Chemistry.

Structural basis for the catalytic mechanism of human phosphodiesterase 9

P. Lemotte, M. Mansour, D. Danley, 2008, Proceedings of the National Academy of Sciences.

Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia

Xiayang Qiu, Dennis E Danley, S. Shenolikar, 2007, Nature Structural &Molecular Biology.

X-ray analysis of HIV-1 proteinase at 2.7 Å resolution confirms structural homology among retroviral enzymes

John P. Overington, John Overington, Tom Blundell, 1989, Nature.

Cloning and Functional Characterization of an NAD+-Dependent DNA Ligase from Staphylococcus aureus

M. Mansour, D. Danley, T. Gootz, 2001, Journal of Bacteriology.

Specificity determinants of human cathepsin s revealed by crystal structures of complexes.

Traian Sulea, Miroslaw Cygler, Robert Ménard, 2003, Biochemistry.

A crystallizable form of RIIbeta regulatory domain obtained by limited proteolysis.

P. Lemotte, K. Fennell, D. Danley, 2000, Acta Crystallographica Section D: Biological Crystallography.

Fluorescence‐based continuous assay for the aspartyl protease of human immunodeficiency virus‐1

D. Danley, K. Geoghegan, R. Spencer, 1990, FEBS Letters.

Expression and secretion of bovine prochymosin in Yarrowia lipolytica

D. Danley, K. Geoghegan, L. Davidow, 1988 .

from Escherichia coli and Proteus rettgeri. Experimental evolution of penicillin G acylases

D. Danley, A. Mccoll, G. Daumy, 2013 .

Expression and regulation of the penicillin G acylase gene from Proteus rettgeri cloned in Escherichia coli

D. Danley, A. Mccoll, G. Daumy, 1986, Journal of Bacteriology.

Differential binding of cyclic adenosine 3' ,5'-monophosphate to the cyclic adenosine 3' ,5'-monophosphate receptor protein in Escherichia coli

D. Danley, J. Botsford, M. Drexler, 1977, Journal of bacteriology.

Potent pyrimidinetrione-based inhibitors of MMP-13 with enhanced selectivity over MMP-14.

D. Danley, J. Pandit, E. Laird, 2005, Bioorganic & medicinal chemistry letters.

Expression of human plasminogen activator inhibitor type-1 (PAI-1) in Escherichia coli as a soluble protein comprised of active and latent forms. Isolation and crystallization of latent PAI-1.

D. Danley, R. Gerard, K. Geoghegan, 1990, Biochimica et biophysica acta.

Crystallization to obtain protein-ligand complexes for structure-aided drug design.

Dennis E Danley, D. Danley, 2006, Acta Crystallographica Section D: Biological Crystallography.

Human liver glycogen phosphorylase inhibitors bind at a new allosteric site.

V. L. Rath, M. Ammirati, D. Danley, 2000, Chemistry & biology.

Crystal structure of nicotinic acid mononucleotide adenylyltransferase from Staphyloccocus aureus: structural basis for NaAD interaction in functional dimer.

D. Danley, Hong Wang, Seungil Han, 2006, Journal of molecular biology.

In vitro biosynthesis of diphthamide, studied with mutant Chinese hamster ovary cells resistant to diphtheria toxin

D. Danley, T. Moehring, J. Moehring, 1984, Molecular and cellular biology.

Structural basis of latency in plasminogen activator inhibitor-1

E. Goldsmith, D. Danley, J. Symerský, 1992, Nature.

Simple procedure for recovery of crystallizable human recombinant renin from mammalian cell-conditioned medium.

D. Danley, A. Lanzetti, K. Geoghegan, 1991, Advances in experimental medicine and biology.

Structure-activity analysis of the purine binding site of human liver glycogen phosphorylase.

David G Myszka, Dennis E Danley, R. Fletterick, 2002, Chemistry & biology.

Identification and characterization of a C‐terminally extended form of recombinant murine IL‐6

D. Danley, I. Otterness, A. Lanzetti, 1991, FEBS letters.

Discovery of a novel series of 6-azauracil-based thyroid hormone receptor ligands: potent, TR beta subtype-selective thyromimetics.

Peter Cornelius, Eunsun Lee, Dennis E Danley, 2003, Bioorganic & medicinal chemistry letters.