Chung-Jung Tsai

发表

Allostery in Disease and in Drug Discovery

R. Nussinov, Chung-Jung Tsai, 2013, Cell.

Unraveling structural mechanisms of allosteric drug action.

R. Nussinov, Chung-Jung Tsai, 2014, Trends in pharmacological sciences.

Allosteric post-translational modification codes.

R. Nussinov, P. Radivojac, Chung-Jung Tsai, 2012, Trends in biochemical sciences.

Folding and binding cascades: Dynamic landscapes and population shifts

R. Nussinov, Chung-Jung Tsai, Sandeep Kumar, 2008, Protein science : a publication of the Protein Society.

In silico protein design by combinatorial assembly of protein building blocks

R. Nussinov, Chung-Jung Tsai, B. Ma, 2004, Protein science : a publication of the Protein Society.

Folding funnels, binding funnels, and protein function

R. Nussinov, Chung-Jung Tsai, Sandeep Kumar, 1999, Protein science : a publication of the Protein Society.

The different ways through which specificity works in orthosteric and allosteric drugs.

R. Nussinov, Chung-Jung Tsai, 2012, Current pharmaceutical design.

Protein-protein interaction networks: how can a hub protein bind so many different partners?

R. Nussinov, Chung-Jung Tsai, B. Ma, 2009, Trends in biochemical sciences.

Allo-network drugs: harnessing allostery in cellular networks.

R. Nussinov, Chung-Jung Tsai, P. Csermely, 2011, Trends in pharmacological sciences.

The stability and dynamics of the human calcitonin amyloid peptide DFNKF.

R. Nussinov, N. Haspel, Chung-Jung Tsai, 2004, Biophysical journal.

Extended disordered proteins: targeting function with less scaffold.

R. Nussinov, Chung-Jung Tsai, Sandeep Kumar, 2003, Trends in biochemical sciences.

A new, structurally nonredundant, diverse data set of protein–protein interfaces and its implications

H. Wolfson, R. Nussinov, Chung-Jung Tsai, 2004, Protein science : a publication of the Protein Society.

Mechanisms of transcription factor selectivity.

R. Nussinov, Chung-Jung Tsai, B. Ma, 2010, Trends in genetics : TIG.

Allostery: absence of a change in shape does not imply that allostery is not at play.

R. Nussinov, Chung-Jung Tsai, A. del Sol, 2008, Journal of molecular biology.

Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms

R. Nussinov, Chung-Jung Tsai, A. del Sol, 2009, Molecular bioSystems.

Gene-specific transcription activation via long-range allosteric shape-shifting.

Ruth Nussinov, Chung-Jung Tsai, R. Nussinov, 2011, The Biochemical journal.

The design of covalent allosteric drugs.

Ruth Nussinov, Chung-Jung Tsai, R. Nussinov, 2015, Annual review of pharmacology and toxicology.

Principles of Allosteric Interactions in Cell Signaling

Ruth Nussinov, Chung-Jung Tsai, R. Nussinov, 2014, Journal of the American Chemical Society.

Multiple conformational selection and induced fit events take place in allosteric propagation.

R. Nussinov, Chung-Jung Tsai, B. Ma, 2014, Biophysical chemistry.

A broad view of scaffolding suggests that scaffolding proteins can actively control regulation and signaling of multienzyme complexes through allostery.

Ruth Nussinov, Chung-Jung Tsai, Buyong Ma, 2013, Biochimica et biophysica acta.

The underappreciated role of allostery in the cellular network.

R. Nussinov, Chung-Jung Tsai, B. Ma, 2013, Annual review of biophysics.

Allosteric conformational barcodes direct signaling in the cell.

R. Nussinov, Chung-Jung Tsai, B. Ma, 2013, Structure.

Dynamic allostery: linkers are not merely flexible.

R. Nussinov, Chung-Jung Tsai, B. Ma, 2011, Structure.

The origin of allosteric functional modulation: multiple pre-existing pathways.

R. Nussinov, Chung-Jung Tsai, B. Ma, 2009, Structure.

How do transcription factors select specific binding sites in the genome?

Ruth Nussinov, Chung-Jung Tsai, Buyong Ma, 2009, Nature Structural &Molecular Biology.

Why Does Binding of Proteins to DNA or Proteins to Proteins Not Necessarily Spell Function?

Ruth Nussinov, Chung-Jung Tsai, Buyong Ma, 2010, ACS chemical biology.

Structural stability and dynamics of an amyloid-forming peptide GNNQQNY from the yeast prion sup-35.

Ruth Nussinov, Chung-Jung Tsai, Buyong Ma, 2006, Biophysical journal.

Allostery without a conformational change? Revisiting the paradigm.

Ruth Nussinov, Chung-Jung Tsai, R. Nussinov, 2015, Current opinion in structural biology.

The free energy landscape in translational science: how can somatic mutations result in constitutive oncogenic activation?

R. Nussinov, Chung-Jung Tsai, 2014, Physical chemistry chemical physics : PCCP.

Autoinhibition in Ras effectors Raf, PI3Kα, and RASSF5: a comprehensive review underscoring the challenges in pharmacological intervention

Ruth Nussinov, Hyunbum Jang, Chung-Jung Tsai, 2018, Biophysical Reviews.

Dynamic Protein Allosteric Regulation and Disease.

R. Nussinov, Chung-Jung Tsai, H. Jang, 2019, Advances in experimental medicine and biology.

Free energy diagrams for protein function.

Ruth Nussinov, Chung-Jung Tsai, R. Nussinov, 2014, Chemistry & biology.

Analysis of ordered and disordered protein complexes reveals structural features discriminating between stable and unstable monomers.

Ruth Nussinov, Chung-Jung Tsai, R. Nussinov, 2004, Journal of molecular biology.

Mechanism and evolution of protein dimerization

R. Nussinov, Chung-Jung Tsai, Dong Xu, 1998, Protein science : a publication of the Protein Society.

Structural motifs at protein‐protein interfaces: Protein cores versus two‐state and three‐state model complexes

Ruth Nussinov, R. Nussinov, Chung-Jung Tsai, 1997, Protein science : a publication of the Protein Society.

Oncoviruses Can Drive Cancer by Rewiring Signaling Pathways Through Interface Mimicry

R. Nussinov, Chung-Jung Tsai, Emine Guven-Maiorov, 2019, Front. Oncol..

Interface-Based Structural Prediction of Novel Host-Pathogen Interactions.

Ruth Nussinov, Chung-Jung Tsai, Buyong Ma, 2018, Methods in molecular biology.

Prediction of Host-Pathogen Interactions for Helicobacter pylori by Interface Mimicry and Implications to Gastric Cancer.

Ruth Nussinov, Chung-Jung Tsai, Buyong Ma, 2017, Journal of molecular biology.

Studies of protein‐protein interfaces: A statistical analysis of the hydrophobic effect

H. Wolfson, R. Nussinov, Chung-Jung Tsai, 1997, Protein science : a publication of the Protein Society.

HMI-PRED: A Web Server for Structural Prediction of Host-Microbe Interactions Based on Interface Mimicry.

R. Nussinov, Chung-Jung Tsai, O. Keskin, 2020, Journal of molecular biology.

Techniques for searching for structural similarities between protein cores, protein surfaces and between protein-protein interfaces

Ruth Nussinov, Haim J. Wolfson, Chung-Jung Tsai, 1996 .

Maximal stabilities of reversible two-state proteins.

Ruth Nussinov, Chung-Jung Tsai, R. Nussinov, 2002, Biochemistry.

The structural basis for cancer treatment decisions

R. Nussinov, Chung-Jung Tsai, H. Jang, 2014, Oncotarget.

The molecular basis of targeting protein kinases in cancer therapeutics.

Ruth Nussinov, Chung-Jung Tsai, R. Nussinov, 2013, Seminars in cancer biology.

Oncogenic K-Ras4B Dimerization Enhances Downstream Mitogen-activated Protein Kinase Signaling

R. Nussinov, Chung-Jung Tsai, O. Keskin, 2020, Journal of Molecular Biology.

'Latent drivers' expand the cancer mutational landscape.

R. Nussinov, Chung-Jung Tsai, 2015, Current opinion in structural biology.

The implications of higher (or lower) success in secondary structure prediction of chain fragments

R. Nussinov, Chung-Jung Tsai, 2005, Protein science : a publication of the Protein Society.

Comparison of protein fragments identified by limited proteolysis and by computational cutting of proteins

Ruth Nussinov, Angelo Fontana, R. Nussinov, 2002, Protein science : a publication of the Protein Society.

Intrinsic protein disorder in oncogenic KRAS signaling

Ruth Nussinov, Jian Zhang, Hyunbum Jang, 2017, Cellular and Molecular Life Sciences.

Synonymous mutations and ribosome stalling can lead to altered folding pathways and distinct minima.

Ruth Nussinov, Chung-Jung Tsai, Chava Kimchi-Sarfaty, 2008, Journal of molecular biology.

Transient, highly populated, building blocks folding model

R. Nussinov, Chung-Jung Tsai, 2007, Cell Biochemistry and Biophysics.

'Pathway drug cocktail': targeting Ras signaling based on structural pathways.

Ruth Nussinov, Chung-Jung Tsai, Carla Mattos, 2013, Trends in molecular medicine.

A new precision medicine initiative at the dawn of exascale computing

R. Nussinov, Chung-Jung Tsai, F. Cheng, 2021, Signal Transduction and Targeted Therapy.

A unified convention for biological assemblies with helical symmetry

R. Nussinov, Chung-Jung Tsai, 2011, Acta crystallographica. Section D, Biological crystallography.

Calmodulin and PI3K Signaling in KRAS Cancers.

Ruth Nussinov, Shaoyong Lu, Jian Zhang, 2017, Trends in cancer.

Ras assemblies and signaling at the membrane.

R. Nussinov, Chung-Jung Tsai, H. Jang, 2020, Current opinion in structural biology.

The Architecture of the TIR Domain Signalosome in the Toll-like Receptor-4 Signaling Pathway

Ozlem Keskin, Ruth Nussinov, Chung-Jung Tsai, 2015, Scientific Reports.

Are Parallel Proliferation Pathways Redundant?

R. Nussinov, Chung-Jung Tsai, Hyun-Oh Jang, 2020, Trends in biochemical sciences.

Protein Folding: Binding of Conformationally Fluctuating Building Blocks Via Population Selection

R. Nussinov, Chung-Jung Tsai, Sandeep Kumar, 2001, Critical reviews in biochemistry and molecular biology.

Principles of nanostructure design with protein building blocks

Ruth Nussinov, Nurit Haspel, Carlos Alemán, 2007, Proteins.

Why Are Some Driver Mutations Rare?

R. Nussinov, Chung-Jung Tsai, H. Jang, 2019, Trends in pharmacological sciences.

Neurodevelopmental disorders, immunity, and cancer are connected

R. Nussinov, Chung-Jung Tsai, H. Jang, 2022, iScience.

Insights into amyloid structural formation and assembly through computational approaches

R. Nussinov, Chung-Jung Tsai, B. Ma, 2004, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

fragment folding and assembly Reducing the computational complexity of protein folding via

H. Wolfson, R. Nussinov, N. Haspel, 2002 .

The (still) underappreciated role of allostery in the cellular network

R. Nussinov, Chung-Jung Tsai, B. Ma, 2019 .

The dynamic mechanism of RASSF5 and MST kinase activation by Ras.

R. Nussinov, Chung-Jung Tsai, D. Fushman, 2017, Physical chemistry chemical physics : PCCP.

Intra-molecular chaperone: the role of the N-terminal in conformational selection and kinetic control

R. Nussinov, Chung-Jung Tsai, B. Ma, 2009, Physical biology.

Thermal unfolding molecular dynamics simulation of Escherichia coli dihydrofolate reductase: Thermal stability of protein domains and unfolding pathway

R. Nussinov, Chung-Jung Tsai, B. Ma, 2002, Proteins.

The different ways through which specificity works in orthosteric and allosteric drugs.

R. Nussinov, Chung-Jung Tsai, 2012, Current pharmaceutical design.

Allosteric regulation of autoinhibition and activation of c-Abl

R. Nussinov, Chung-Jung Tsai, Mingzhen Zhang, 2022, Computational and structural biotechnology journal.

Intrinsic protein disorder in oncogenic KRAS signaling

R. Nussinov, Shuai Li, Jian Zhang, 2017, Cellular and Molecular Life Sciences.

HMI-PRED 2.0: a biologist-oriented web application for prediction of host–microbe protein–protein interaction by interface mimicry

R. Nussinov, Chung-Jung Tsai, O. Keskin, 2022, Bioinform..

A New View of Activating Mutations in Cancer

R. Nussinov, Chung-Jung Tsai, Hyunbum Jang, 2022, Cancer research.

Nanostructure design using protein building blocks enhanced by conformationally constrained synthetic residues.

Ruth Nussinov, Nurit Haspel, Carlos Alemán, 2007, Biochemistry.

Energy landscape of amyloidogenic peptide oligomerization by parallel-tempering molecular dynamics simulation: significant role of Asn ladder.

Ruth Nussinov, Meital Reches, Ehud Gazit, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Folding funnels and conformational transitions via hinge-bending motions

Ruth Nussinov, Chung-Jung Tsai, Buyong Ma, 2007, Cell Biochemistry and Biophysics.

Oncogenic KRAS signaling and YAP1/β-catenin: Similar cell cycle control in tumor initiation.

Ruth Nussinov, Tamás Korcsmáros, Peter Csermely, 2016, Seminars in cell & developmental biology.

Independent and core pathways in oncogenic KRAS signaling

Ruth Nussinov, Hyunbum Jang, Chung-Jung Tsai, 2016, Expert review of proteomics.

K-Ras4B/calmodulin/PI3Kα: A promising new adenocarcinoma-specific drug target?

Ozlem Keskin, Ruth Nussinov, Hyunbum Jang, 2016, Expert opinion on therapeutic targets.

Review: Precision medicine and driver mutations: Computational methods, functional assays and conformational principles for interpreting cancer drivers

Ruth Nussinov, Feixiong Cheng, Hyunbum Jang, 2019, PLoS Comput. Biol..

A New View of Pathway-Driven Drug Resistance in Tumor Proliferation.

Ruth Nussinov, Hyunbum Jang, Chung-Jung Tsai, 2017, Trends in pharmacological sciences.

Protein ensembles link genotype to phenotype

Ruth Nussinov, Hyunbum Jang, Chung-Jung Tsai, 2019, PLoS Comput. Biol..

Precision medicine review: rare driver mutations and their biophysical classification

Ruth Nussinov, Feixiong Cheng, Hyunbum Jang, 2019, Biophysical Reviews.

Principles of K-Ras effector organization and the role of oncogenic K-Ras in cancer initiation through G1 cell cycle deregulation

Ozlem Keskin, Ruth Nussinov, Hyunbum Jang, 2015, Expert review of proteomics.

Phosphorylation and Driver Mutations in PI3Kα and PTEN Autoinhibition

R. Nussinov, Chung-Jung Tsai, Mingzhen Zhang, 2020, Molecular Cancer Research.

Anticancer drug resistance: An update and perspective.

R. Nussinov, Chung-Jung Tsai, Hyunbum Jang, 2021, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Autoinhibition can identify rare driver mutations and advise pharmacology

Ruth Nussinov, Chung-Jung Tsai, Hyunbum Jang, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Does Ras Activate Raf and PI3K Allosterically?

R. Nussinov, Chung-Jung Tsai, Hyunbum Jang, 2019, Front. Oncol..

Is Nanoclustering essential for all oncogenic KRas pathways? Can it explain why wild-type KRas can inhibit its oncogenic variant?

Ruth Nussinov, Hyunbum Jang, Chung-Jung Tsai, 2019, Seminars in cancer biology.

RASSF5: An MST activator and tumor suppressor in vivo but opposite in vitro.

Ruth Nussinov, Hyunbum Jang, Chung-Jung Tsai, 2016, Current opinion in structural biology.

Allostery: Allosteric Cancer Drivers and Innovative Allosteric Drugs.

R. Nussinov, Chung-Jung Tsai, Mingzhen Zhang, 2022, Journal of molecular biology.

Pan-cancer clinical impact of latent drivers from double mutations

R. Nussinov, Chung-Jung Tsai, Nurcan Tuncbag, 2023, Communications Biology.

A New View of Ras Isoforms in Cancers.

Ruth Nussinov, Hyunbum Jang, Chung-Jung Tsai, 2016, Cancer research.

Artificial intelligence approaches to human-microbiome protein-protein interactions.

R. Nussinov, Chung-Jung Tsai, O. Keskin, 2022, Current opinion in structural biology.

Allostery in Its Many Disguises: From Theory to Applications.

Ruth Nussinov, Ivet Bahar, Dima Kozakov, 2019, Structure.

Mechanism of activation and the rewired network: New drug design concepts

R. Nussinov, Chung-Jung Tsai, Nurcan Tuncbag, 2021, Medicinal research reviews.

The Key Role of Calmodulin in KRAS-Driven Adenocarcinomas

Ozlem Keskin, Ruth Nussinov, Hyunbum Jang, 2015, Molecular Cancer Research.

Hydrophobic folding units at protein‐protein interfaces: Implications to protein folding and to protein‐protein association

R Nussinov, R. Nussinov, Chung-Jung Tsai, 1997, Protein science : a publication of the Protein Society.

Studies of protein‐protein interfaces: A statistical analysis of the hydrophobic effect

H. Wolfson, R. Nussinov, Chung-Jung Tsai, 1997, Protein science : a publication of the Protein Society.

Emerging Allosteric Mechanism of EGFR Activation in Physiological and Pathological Contexts

Ruth Nussinov, Chung-Jung Tsai, R. Nussinov, 2019, Biophysical journal.

Allosteric activation of RAF in the MAPK signaling pathway.

Ruth Nussinov, Chung-Jung Tsai, R. Nussinov, 2018, Current opinion in structural biology.

Oncogenic Ras Isoforms Signaling Specificity at the Membrane.

Ruth Nussinov, Hyunbum Jang, Chung-Jung Tsai, 2017, Cancer research.

Structural host-microbiota interaction networks

Ruth Nussinov, Chung-Jung Tsai, Emine Guven-Maiorov, 2017, PLoS Comput. Biol..

Hollow core of Alzheimer’s Aβ42 amyloid observed by cryoEM is relevant at physiological pH

Ruth Nussinov, Chung-Jung Tsai, Buyong Ma, 2010, Proceedings of the National Academy of Sciences.

The Mystery of Rap1 Suppression of Oncogenic Ras.

R. Nussinov, Chung-Jung Tsai, Mingzhen Zhang, 2020, Trends in cancer.

How can same-gene mutations promote both cancer and developmental disorders?

R. Nussinov, Chung-Jung Tsai, Hyunbum Jang, 2022, Science advances.

Diameters of single-walled carbon nanotubes (SWCNTs) and related nanochemistry and nanobiology

R. Nussinov, Chung-Jung Tsai, B. Ma, 2010 .

Pathogen mimicry of host protein-protein interfaces modulates immunity.

R. Nussinov, Chung-Jung Tsai, Emine Guven-Maiorov, 2016, Seminars in cell & developmental biology.

TRAF3 signaling: Competitive binding and evolvability of adaptive viral molecular mimicry☆

R. Nussinov, Chung-Jung Tsai, O. Keskin, 2016, Biochimica et Biophysica Acta (BBA) - General Subjects.

Mutational Analysis and Allosteric Effects in the HIV-1 Capsid Protein Carboxyl-Terminal Dimerization Domain

Stephen Z. D. Cheng, R. Nussinov, Chung-Jung Tsai, 2009, Biomacromolecules.

Electrostatic strengths of salt bridges in thermophilic and mesophilic glutamate dehydrogenase monomers

R. Nussinov, Chung-Jung Tsai, Sandeep Kumar, 2000, Proteins.

Calmodulin and IQGAP1 activation of PI3Kα and Akt in KRAS, HRAS and NRAS-driven cancers.

R. Nussinov, Chung-Jung Tsai, Mingzhen Zhang, 2017, Biochimica et biophysica acta. Molecular basis of disease.

Oncogenic KRas mobility in the membrane and signaling response.

Ruth Nussinov, Hyunbum Jang, Chung-Jung Tsai, 2019, Seminars in cancer biology.

Oligomerization and nanocluster organization render specificity

R. Nussinov, Chung-Jung Tsai, Hyunbum Jang, 2015, Biological reviews of the Cambridge Philosophical Society.

A Unified View of “How Allostery Works”

Ruth Nussinov, Chung-Jung Tsai, R. Nussinov, 2014, PLoS Comput. Biol..

Discovery of Latent Drivers from Double Mutations in Pan-Cancer Data Reveal their Clinical Impact

R. Nussinov, Chung-Jung Tsai, Nurcan Tuncbag, 2021, bioRxiv.

Hydrophobic folding units derived from dissimilar monomer structures and their interactions

R. Nussinov, Chung-Jung Tsai, C. J. Tsai, 1997, Protein science : a publication of the Protein Society.

Reducing the computational complexity of protein folding via fragment folding and assembly

H. Wolfson, R. Nussinov, Chung-Jung Tsai, 2003, Protein science : a publication of the Protein Society.

Hierarchical protein folding pathways: A computational study of protein fragments

Ruth Nussinov, Nurit Haspel, Haim Wolfson, 2003, Proteins.

Contribution of Salt Bridges Toward Protein Thermostability

R Nussinov, R. Nussinov, Chung-Jung Tsai, 2000, Journal of biomolecular structure & dynamics.

Distinguishing between sequential and nonsequentially folded proteins: Implications for folding and misfolding

R. Nussinov, J. Maizel, Chung-Jung Tsai, 1999, Protein science : a publication of the Protein Society.

Allostery, and how to define and measure signal transduction.

R. Nussinov, Chung-Jung Tsai, Hyunbum Jang, 2022, Biophysical chemistry.

Building Blocks, Hinge-Bending Motions and Protein Topology

Ruth Nussinov, Chung-Jung Tsai, R. Nussinov, 2001, Journal of biomolecular structure & dynamics.

Structure by design: from single proteins and their building blocks to nanostructures.

Jie Zheng, Ruth Nussinov, Carlos Alemán, 2006, Trends in biotechnology.

A hierarchical, building-block-based computational scheme for protein structure prediction

Sandeep Kumar, Ruth Nussinov, Haim J. Wolfson, 2001, IBM J. Res. Dev..

Neurodevelopmental disorders, like cancer, are connected to impaired chromatin remodelers, PI3K/mTOR, and PAK1-regulated MAPK

R. Nussinov, Chung-Jung Tsai, Nurcan Tuncbag, 2023, Biophysical Reviews.

Structured disorder and conformational selection

R. Nussinov, Chung-Jung Tsai, Sandeep Kumar, 2001, Proteins.

Neurodevelopmental disorders and cancer networks share pathways, but differ in mechanisms, signaling strength, and outcome

R. Nussinov, Chung-Jung Tsai, Nurcan Tuncbag, 2023, bioRxiv.

Computational Structural Biology: Successes, Future Directions, and Challenges

Ruth Nussinov, Amarda Shehu, Hyunbum Jang, 2019, Molecules.

Principles of Shape‐Driven Nanostructure Design via Self‐Assembly of Protein Building Blocks

R. Nussinov, Chung-Jung Tsai, C. Alemán, 2013 .

Symmetry-based self-assembled nanotubes constructed using native protein structures: the key role of flexible linkers.

Ruth Nussinov, Haim J Wolfson, Chung-Jung Tsai, 2011, Protein and peptide letters.

The Hydrophobic Effect: A New Insight from Cold Denaturation and a Two-State Water Structure

R. Nussinov, J. Maizel, Chung-Jung Tsai, 2002, Critical reviews in biochemistry and molecular biology.

The structural basis of BCR-ABL recruitment of GRB2 in chronic myelogenous leukemia

R. Nussinov, Chung-Jung Tsai, Mingzhen Zhang, 2022, Biophysical journal.

Open Structural Data in Precision Medicine.

R. Nussinov, Chung-Jung Tsai, F. Cheng, 2022, Annual review of biomedical data science.

Oncogenic K-Ras4B dimerization enhances downstream MAPK signaling.

R. Nussinov, Chung-Jung Tsai, O. Keskin, 2020, Journal of molecular biology.

Protein–Ligand Interactions: Energetic Contributions and Shape Complementarity

H. Wolfson, R. Nussinov, R. Norel, 2001 .

Autoinhibition in Ras effectors Raf, PI3Kα, and RASSF5: a comprehensive review underscoring the challenges in pharmacological intervention

R. Nussinov, Chung-Jung Tsai, D. Fushman, 2018, Biophysical Reviews.

fragment folding and assembly Reducing the computational complexity of protein folding via

Ruth Nussinov, Nurit Haspel, Haim Wolfson, 2002 .

Self-assembly of fused homo-oligomers to create nanotubes.

H. Wolfson, R. Nussinov, Chung-Jung Tsai, 2008, Methods in molecular biology.

Factors enhancing protein thermostability.

R. Nussinov, Chung-Jung Tsai, Sandeep Kumar, 2000, Protein engineering.

A dataset of protein-protein interfaces generated with a sequence-order-independent comparison technique.

H. Wolfson, R. Nussinov, Chung-Jung Tsai, 1996, Journal of molecular biology.

Web interface for 3D visualization and analysis of SARS-CoV-2—human mimicry and interactions

R. Nussinov, Chung-Jung Tsai, O. Keskin, 2021, Bioinform..

Hydrogen bonds and salt bridges across protein-protein interfaces.

R. Nussinov, Chung-Jung Tsai, C. J. Tsai, 1997, Protein engineering.

Temperature range of thermodynamic stability for the native state of reversible two-state proteins.

R. Nussinov, Chung-Jung Tsai, Sandeep Kumar, 2003, Biochemistry.

Folding funnels and binding mechanisms.

R. Nussinov, Chung-Jung Tsai, Sandeep Kumar, 1999, Protein engineering.

Synonymous mutations and ribosome stalling can lead to altered folding pathways and distinct minima.

R. Nussinov, Chung-Jung Tsai, M. Gottesman, 2008, Journal of molecular biology.

Designing a Nanotube Using Naturally Occurring Protein Building Blocks

Jie Zheng, Ruth Nussinov, Chung-Jung Tsai, 2006, PLoS Comput. Biol..

Gene-specific transcription activation via long-range allosteric shape-shifting.

R. Nussinov, Chung-Jung Tsai, 2011, The Biochemical journal.

RASSF5: An MST activator and tumor suppressor in vivo but opposite in vitro.

R. Nussinov, Chung-Jung Tsai, D. Fushman, 2016, Current opinion in structural biology.

The Key Role of Calmodulin in KRAS-Driven Adenocarcinomas

R. Nussinov, Chung-Jung Tsai, O. Keskin, 2015, Molecular Cancer Research.

A proposed structural model for amyloid fibril elongation: domain swapping forms an interdigitating beta-structure polymer.

R Nussinov, R. Nussinov, Chung-Jung Tsai, 2001, Protein engineering.

Tandem Domains with Tuned Interactions Are a Powerful Biological Design Principle

R. Nussinov, Chung-Jung Tsai, 2015, PLoS biology.

Anatomy of protein structures: visualizing how a one-dimensional protein chain folds into a three-dimensional shape.

R. Nussinov, J. Maizel, Chung-Jung Tsai, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Folding and binding cascades: Shift

R. Nussinov, Chung-Jung Tsai, B. Mat, 2017 .

Transition-state ensemble in enzyme catalysis: possibility, reality, or necessity?

R Nussinov, R. Nussinov, Chung-Jung Tsai, 2000, Journal of theoretical biology.

Thermodynamic differences among homologous thermophilic and mesophilic proteins.

R Nussinov, R. Nussinov, Chung-Jung Tsai, 2001, Biochemistry.

The building block folding model and the kinetics of protein folding.

R. Nussinov, Chung-Jung Tsai, C. J. Tsai, 2001, Protein engineering.

Binding and folding: in search of intramolecular chaperone-like building block fragments.

R Nussinov, R. Nussinov, Chung-Jung Tsai, 2000, Protein engineering.

Reducing the computational complexity of protein folding via fragment folding and assembly

H. Wolfson, Chung-Jung Tsai, Nurit Haspel, 2003, Protein science : a publication of the Protein Society.

UvA-DARE (Digital Academic Repository) Allostery in Its Many Disguises: From Theory to Applications

S. Wodak, M. Wyart, Chung-Jung Tsai, 2022 .

Protein-protein interfaces: architectures and interactions in protein-protein interfaces and in protein cores. Their similarities and differences.

H. Wolfson, R. Nussinov, Chung-Jung Tsai, 1996, Critical reviews in biochemistry and molecular biology.

hydrophobic effect Studies of protein-protein interfaces : A statistical analysis of the

Chung-Jung Tsai, Ruth, 2002 .