L. T. Ten Eyck

发表

2.2 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitor.

Susan S. Taylor, J. Zheng, E. Trafny, 1993, Acta crystallographica. Section D, Biological crystallography.

Protein docking using continuum electrostatics and geometric fit.

L. T. Ten Eyck, J. Mandell, V. Roberts, 2001, Protein engineering.

Rapid atomic density methods for molecular shape characterization.

L. T. Ten Eyck, J. C. Mitchell, R. Kerr, 2001, Journal of molecular graphics & modelling.

Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure.

Susan S. Taylor, N. Xuong, L. T. Ten Eyck, 2003, Journal of molecular biology.

Crystal structure of the E230Q mutant of cAMP‐dependent protein kinase reveals an unexpected apoenzyme conformation and an extended N‐terminal A helix

Susan S. Taylor, N. Xuong, L. T. Ten Eyck, 2005, Protein science : a publication of the Protein Society.

The cAMP binding domain: an ancient signaling module.

Susan S. Taylor, D. Goodsell, L. T. Ten Eyck, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase.

J. Zheng, D. Knighton, N. Xuong, 1991, Science.

Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase.

J. Zheng, D. Knighton, N. Xuong, 1991, Science.

Surface comparison of active and inactive protein kinases identifies a conserved activation mechanism

Susan S. Taylor, L. T. Ten Eyck, N. Haste, 2006, Proceedings of the National Academy of Sciences.

Automated extraction of backbone deuteration levels from amide H/2H mass spectrometry experiments

L. T. Ten Eyck, E. Komives, G. Anand, 2006, Protein science : a publication of the Protein Society.

A helix scaffold for the assembly of active protein kinases

Lynn F. Ten Eyck, Susan S. Taylor, Alexandr P. Kornev, 2008, Proceedings of the National Academy of Sciences.

Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima

Mitchell D. Miller, A. Deacon, L. T. Ten Eyck, 2012, Proteins.

Conformation-invariant structures of the alpha1beta1 human hemoglobin dimer.

L. T. Ten Eyck, B. Zimm, L. F. Eyck, 1997, Journal of molecular biology.

Protein structural alignment for detection of maximally conserved regions.

L. T. Ten Eyck, V. Kotlovyi, W. L. Nichols, 2003, Biophysical chemistry.

Vaccinia Virus Immunomodulator A46: A Lipid and Protein-Binding Scaffold for Sequestering Host TIR-Domain Proteins

Terry K. Smith, G. A. Bezerra, L. T. Ten Eyck, 2016, PLoS pathogens.

A conserved helix motif complements the protein kinase core.

S. Taylor, L. T. Ten Eyck, I. Tsigelny, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Conserved spatial patterns across the protein kinase family.

Susan S. Taylor, L. T. Ten Eyck, A. Kornev, 2008, Biochimica et biophysica acta.

Structural framework for the protein kinase family.

J. Zheng, D. Knighton, S. Taylor, 1992, Annual review of cell biology.

cAMP-dependent protein kinase and the protein kinase family.

J. Zheng, D. Knighton, S. Taylor, 1992, Faraday discussions.

From structure to the dynamic regulation of a molecular switch: A journey over 3 decades

Susan S. Taylor, L. T. Ten Eyck, Jian Wu, 2021, The Journal of biological chemistry.

Crystal structure of a cAMP-dependent protein kinase mutant at 1.26A: new insights into the catalytic mechanism.

Lynn F Ten Eyck, Susan S. Taylor, N. Xuong, 2004, Journal of molecular biology.

Catalytic subunit of cyclic AMP-dependent protein kinase: structure and dynamics of the active site cleft.

S. Taylor, L. T. Ten Eyck, Madhusudan, 1999, Pharmacology & therapeutics.

A binary complex of the catalytic subunit of cAMP-dependent protein kinase and adenosine further defines conformational flexibility.

N. Xuong, S. Taylor, L. T. Ten Eyck, 1997, Structure.

Catalytic subunit of cAMP-dependent protein kinase: electrostatic features and peptide recognition.

S. Taylor, L. T. Ten Eyck, I. Tsigelny, 1998, Biopolymers.

Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains

N. Xuong, S. Taylor, L. T. Ten Eyck, 1995, Science.

Structural basis of the intrasteric regulation of myosin light chain kinases.

D. Knighton, S. Taylor, L. T. Ten Eyck, 1992, Science.

Fast Fourier transform calculation of electron density maps.

L. T. Ten Eyck, 1985, Methods in enzymology.

Rigid domains in proteins: An algorithmic approach to their identification

G. Rose, L. T. Ten Eyck, B. Zimm, 1995, Proteins.

Structural features that specify tyrosine kinase activity deduced from homology modeling of the epidermal growth factor receptor.

J. Zheng, D. Knighton, S. Taylor, 1993, Proceedings of the National Academy of Sciences of the United States of America.

The protein kinase resource.

P E Bourne, I N Shindyalov, M Gribskov, 1997, Trends in biochemical sciences.

Combining H/D exchange mass spectroscopy and computational docking reveals extended DNA-binding surface on uracil-DNA glycosylase

Sheng Li, John A. Tainer, Tong Liu, 2012, Nucleic acids research.

Crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MgATP and peptide inhibitor.

J. Zheng, D. Knighton, N. Xuong, 1993, Biochemistry.

cAMP-dependent protein kinase defines a family of enzymes.

J. Zheng, D. Knighton, S. Taylor, 1993, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Structure of the lysozyme from bacteriophage T4: an electron density map at 2.4 A resolution.

B. Matthews, L. T. Ten Eyck, S. Remington, 1978, Journal of molecular biology.

Predicting protein–DNA interactions by full search computational docking

Sheng Li, L. T. Ten Eyck, V. Roberts, 2013, Proteins.

Computational reconstruction of multidomain proteins using atomic force microscopy data.

Jean-Luc Pellequer, Lynn F Ten Eyck, Pierre Parot, 2012, Structure.

Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic subunit of cAMP-dependent protein kinase.

K C Nicolaou, N. Xuong, S. Taylor, 1999, Biochemistry.

600 ps molecular dynamics reveals stable substructures and flexible hinge points in cAMP dependent protein kinase.

S. Taylor, L. T. Ten Eyck, I. Tsigelny, 1999, Biopolymers.

2.0 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with a peptide inhibitor and detergent.

D. Knighton, N. Xuong, S. Taylor, 1993, Acta crystallographica. Section D, Biological crystallography.

Interfaces in Molecular Docking

Julie C. Mitchell, L. T. Ten Eyck, Sharokina Shahbaz, 2004 .

Crystal structures of RIalpha subunit of cyclic adenosine 5'-monophosphate (cAMP)-dependent protein kinase complexed with (Rp)-adenosine 3',5'-cyclic monophosphothioate and (Sp)-adenosine 3',5'-cyclic monophosphothioate, the phosphothioate analogues of cAMP.

Susan S. Taylor, L. T. Ten Eyck, Jian Wu, 2004, Biochemistry.

The structure and stability of thermolysin.

B. Matthews, L. T. Ten Eyck, L. Weaver, 1976, Experientia. Supplementum.

Comparative surface geometry of the protein kinase family

Susan S. Taylor, L. T. Ten Eyck, N. Kannan, 2009, Protein science : a publication of the Protein Society.

Finding needles in haystacks: Reranking DOT results by using shape complementarity, cluster analysis, and biological information

Julie C Mitchell, Igor Tsigelny, Lynn F Ten Eyck, 2003, Proteins.

R-subunit isoform specificity in protein kinase A: distinct features of protein interfaces in PKA types I and II by amide H/2H exchange mass spectrometry.

Susan S. Taylor, L. T. Ten Eyck, E. Komives, 2007, Journal of molecular biology.

Crystal structures of the catalytic subunit of cAMP-dependent protein kinase reveal general features of the protein kinase family.

D. Knighton, S. Taylor, L. T. Ten Eyck, 1993, Receptor.