I. H. Segel

发表

Crystal structure of ATP sulfurylase from Penicillium chrysogenum: insights into the allosteric regulation of sulfate assimilation.

I. MacRae, I. H. Segel, A. Fisher, 2001, Biochemistry.

Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems

I. H. Segel, 1975 .

Sulfate-activating enzymes.

I. H. Segel, F. Renosto, P. Seubert, 1987, Methods in enzymology.

Computer‐assisted simulations of phosphofructokinase‐1 kinetics using simplified velocity equations

I. H. Segel, H. Roy, Joyce D. Diwan, 2001 .

A simple method for calculating the dissociation constant of a receptor (or enzyme).unlabeled ligand complex from radioligand displacement measurements.

I. H. Segel, F. Renosto, R. L. Martin, 1991, Archives of biochemistry and biophysics.

pH and Buffers

I. H. Segel, L. D. Segel, 2001 .

Synthesis and characterization of sodium cysteine-S-sulfate monohydrate.

I. H. Segel, Marvin J. Johnson, M. J. Johnson, 1963, Analytical biochemistry.

Specificity of transport processes for sulfur, selenium, and molybdenum anions by filamentous fungi.

I. H. Segel, J. Tweedie, 1970, Biochimica et biophysica acta.

Ligand-induced structural changes in adenosine 5'-phosphosulfate kinase from Penicillium chrysogenum.

I. H. Segel, A. Fisher, E. Lansdon, 2002, Biochemistry.

Purification and characterization of bile salt sulfotransferase from human liver.

L. J. Chen, I. H. Segel, 1985, Archives of biochemistry and biophysics.

The "regulatory" sulfhydryl group of Penicillium chrysogenum ATP sulfurylase. Cooperative ligand binding after SH modification; chemical and thermodynamic properties.

I. H. Segel, F. Renosto, R. L. Martin, 1989, The Journal of biological chemistry.

Regulation of inorganic sulfate activation in filamentous fungi. Allosteric inhibition of ATP sulfurylase by 3'-phosphoadenosine-5'-phosphosulfate.

I. H. Segel, F. Renosto, R. L. Martin, 1990, The Journal of biological chemistry.

Cloning and sequencing of ATP sulfurylase from Penicillium chrysogenum. Identification of a likely allosteric domain.

H. C. Patel, I. H. Segel, B. Foster, 1994, The Journal of biological chemistry.

Characterization of the adenine binding sites of two Dolichos biflorus lectins.

I. H. Segel, M. Etzler, D. Roberts, 1992, Biochemistry.

Kinetic properties of ATP sulfurylase and APS kinase from Thiobacillus denitrificans.

P. D. Donohoue, I. H. Segel, A. Fisher, 2009, Archives of biochemistry and biophysics.

GLYCOGEN ACCUMULATION BY WILD-TYPE AND URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHORYLASE-NEGATIVE STRAINS OF ESCHERICHIA COLI.

N. Sigal, I. H. Segel, J. Cattanéo, 1964, Archives of biochemistry and biophysics.

Characterization of an ammonium transport system in filamentous fungi with methylammonium-14C as the substrate.

I. H. Segel, C. Burton, S. L. Hackette, 1970, The Journal of biological chemistry.

Mechanism of the Antimicrobial Action of Pyrithione: Effects on Membrane Transport, ATP Levels, and Protein Synthesis

I. H. Segel, C. Chandler, Irwin H. Segel, 1978, Antimicrobial Agents and Chemotherapy.

Neurospora crassa protein kinase. Purification, properties, and kinetic mechanism.

I. H. Segel, M. Gold, 1974, The Journal of biological chemistry.

Glycogen phosphorylase of Neurospora crassa.

I. H. Segel, D. Shepherd, 1969, Archives of biochemistry and biophysics.

Adenosine triphosphate sulfurylase from Penicillium chrysogenum. II. Physical, kinetic, and regulatory properties.

I. H. Segel, J. Tweedie, 1971, The Journal of biological chemistry.

Equilibrium ligand binding assays using labeled substrates: nature of the errors introduced by radiochemical impurities.

I. H. Segel, S. Builder, 1978, Analytical biochemistry.

Intracellular Localization of Nigeran in the Wall of Aspergillus aculeatus by Autoradiography with the Electron Microscope

I. H. Segel, M. Gold, C. Stocking, 1974, Journal of bacteriology.

Isolation and characterization of glutathione reductase from Penicillium chrysogenum.

I. H. Segel, T. Woodin, Terry S. Woodin, 1968, Biochimica et biophysica acta.

Growth of Escherichia coli on selenate.

R. E. Huber, I. H. Segel, R. Criddle, 1967, Biochimica et Biophysica Acta.

Induction of Positive Cooperativity by Amino Acid Replacements within the C-terminal Domain of Penicillium chrysogenum ATP Sulfurylase*

I. MacRae, I. H. Segel, A. Fisher, 2000, The Journal of Biological Chemistry.

ATP sulfurylase from higher plants : purification and preliminary kinetics studies on the cabbage leaf enzyme.

I. H. Segel, T. Osslund, C. Chandler, 1982, Plant physiology.

Neurospora crassa glucogen phosphorylase: interconversion and kinetic properties of the "active" form.

I. H. Segel, M. Gold, R. Farrand, 1974, Archives of biochemistry and biophysics.

Kinetic and chemical properties of ATP sulphurylase from Penicillin chrysogenum.

I. H. Segel, J. Farley, P. Seubert, 1979, Ciba Foundation symposium.

Multiplicity and regulation of amino acid transport in Penicillium chrysogenum.

I. H. Segel, P. Benko, T. C. Wood, 1969, Archives of biochemistry and biophysics.

Specificity and regulation of methionine transport in filamentous fungi

I. H. Segel, P. Benko, T. C. Wood, 1967 .

ATP sulfurylase from Penicillium chrysogenum. Molecular basis of the sigmoidal velocity curves induced by sulfhydryl group modification.

I. H. Segel, F. Renosto, R. L. Martin, 1987, The Journal of biological chemistry.

Glutathione reductase-dependent metabolism of cysteine-S-sulfate by Penicillium chrysogenum.

I. H. Segel, T. Woodin, 1968, Biochimica et Biophysica Acta.

Regulation of Nigeran Accumulation by Aspergillus aculeatus

I. H. Segel, M. Gold, D. Mitzel, 1973, Journal of bacteriology.

Effect of Weak Acids on Amino Acid Transport by Penicillium chrysogenum: Evidence for a Proton or Charge Gradient as the Driving Force

I. H. Segel, I H Segel, D. R. Hunter, 1973, Journal of bacteriology.

APS kinase from Penicillium chrysogenum. Dissociation and reassociation of subunits as the basis of the reversible heat inactivation.

I. H. Segel, F. Renosto, P. Seubert, 1985, The Journal of biological chemistry.

Regulation of Nitrate Uptake in Penicillium chrysogenum by Ammonium Ion.

I. H. Segel, J. Livoni, J. Goldsmith, 1973, Plant physiology.

Evidence for two distinct intracellular pools of inorganic sulfate in Penicillium notatum

I. H. Segel, D. R. Hunter, 1985, Journal of bacteriology.

Acidic and basic amino acid transport systems of Penicillium chrysogenum.

I. H. Segel, D. R. Hunter, Douglas R. Hunter, 1971, Archives of biochemistry and biophysics.

Specificity and Control of Choline–O-Sulfate Transport in Filamentous Fungi

I. H. Segel, P. Nissen, T. C. Wood, 1968, Journal of bacteriology.

Escherichia coli polyglucose phosphorylases.

I. H. Segel, G. S. Chen, 1968, Archives of biochemistry and biophysics.

Choline sulfokinase of Penicillium chrysogenum: partial purification and kinetic mechanism.

I. H. Segel, F. Renosto, 1977, Archives of biochemistry and biophysics.

The inorganic sulfate transport system of Penicillium chrysogenum.

I. H. Segel, L. A. Yamamoto, Lawrence A. Yamamoto, 1966, Archives of biochemistry and biophysics.

Kinetics of sulfate transport by Penicillium notatum. Interactions of sulfate, protons, and calcium.

I. H. Segel, J. Cuppoletti, 1975, Biochemistry.

Allosteric inhibition via R-state destabilization in ATP sulfurylase from Penicillium chrysogenum

I. MacRae, I. H. Segel, A. Fisher, 2002, Nature Structural Biology.

CRYSTAL STRUCTURE OF ATP SULFURYLASE FROM PENICILLIUM CHRYSOGENUM

I. MacRae, I. H. Segel, A. Fisher, 2001 .

Neurospora crassa glycogen phosphorylase: characterization and kinetics via a new radiochemical assay for phosphorolysis.

I. H. Segel, D. Shepherd, S. Rosenthal, 1969, Archives of biochemistry and biophysics.

Crystal structure of Saccharomyces cerevisiae 3'-phosphoadenosine-5'-phosphosulfate reductase complexed with adenosine 3',5'-bisphosphate.

I. H. Segel, A. Fisher, D. Lemongello, 2008, Biochemistry.

Characterization of the cellulose-binding domain of the Clostridium cellulovorans cellulose-binding protein A

I. H. Segel, O. Shoseyov, R. Doi, 1993, Journal of bacteriology.

Human 3'-phosphoadenosine 5'-phosphosulfate synthetase (isoform 1, brain): kinetic properties of the adenosine triphosphate sulfurylase and adenosine 5'-phosphosulfate kinase domains.

I. H. Segel, A. Fisher, E. Lansdon, 2004, Biochemistry.

ATP sulfurylase from the hyperthermophilic chemolithotroph Aquifex aeolicus.

I. MacRae, I. H. Segel, A. Fisher, 2002, Archives of biochemistry and biophysics.

Adenosine 5′-Phosphosulfate Kinase from Penicillium chrysogenum

I. MacRae, I. H. Segel, A. Rose, 1998, The Journal of Biological Chemistry.

ATP sulfurylase from filamentous fungi: which sulfonucleotide is the true allosteric effector?

I. MacRae, I. H. Segel, 1997, Archives of biochemistry and biophysics.

Adenosine triphosphate sulfurylase from Penicillium chrysogenum equilibrium binding, substrate hydrolysis, and isotope exchange studies.

I. H. Segel, J. Farley, G. Nakayama, 1978, Archives of biochemistry and biophysics.

Structure of the two-domain hexameric APS kinase from Thiobacillus denitrificans: structural basis for the absence of ATP sulfurylase activity.

I. H. Segel, A. Fisher, S. Gay, 2009, Acta crystallographica. Section D, Biological crystallography.

Kinetic and Stability Properties of Penicillium chrysogenum ATP Sulfurylase Missing the C-terminal Regulatory Domain*

I. MacRae, I. H. Segel, A. Fisher, 2004, Journal of Biological Chemistry.

Crystal structure of adenosine 5'-phosphosulfate kinase from Penicillium chrysogenum.

I. MacRae, I. H. Segel, A. Fisher, 2000, Biochemistry.

Adenosine-5'-phosphosulfate kinase from Penicillium chrysogenum: ligand binding properties and the mechanism of substrate inhibition.

I. H. Segel, F. Renosto, R. L. Martin, 1991, Archives of biochemistry and biophysics.

Adenosine 5'-phosphosulfate kinase from Penicillium chrysogenum. Determining ligand dissociation constants of binary and ternary complexes from the kinetics of enzyme inactivation.

I. H. Segel, F. Renosto, P. Seubert, 1985, The Journal of biological chemistry.

Adenosine triphosphate sulfurylase from penicillium chrysogenum. Steady state kinetics of the forward and reverse reactions.

I. H. Segel, J. Farley, Y. Yang, 1976, Journal of Biological Chemistry.

Crystal structure of the bifunctional ATP sulfurylase-APS kinase from the chemolithotrophic thermophile Aquifex aeolicus.

I. H. Segel, A. Fisher, E. Lansdon, 2007, Journal of molecular biology.

Optimizing an enzyme for its physiological role: Structural and functional comparisons of ATP sulfurylases from three different organisms

I. MacRae, I. H. Segel, A. Fisher, 2005 .

Temperature effects on the allosteric transition of ATP sulfurylase from Penicillium chrysogenum.

I. MacRae, I. H. Segel, A. Fisher, 2001, Archives of biochemistry and biophysics.

Simplified Velocity Equations for Characterizing the Partial Inhibition or Nonessential Activation of Bireactant Enzymes

I. H. Segel, W. deWolf, 2000, Journal of enzyme inhibition.

Adenosine 5'-phosphosulfate (APS) kinase: diagnosing the mechanism of substrate inhibition.

I. MacRae, I. H. Segel, 1999, Archives of biochemistry and biophysics.

Sulfate-activating enzymes of Penicillium chrysogenum. The ATP sulfurylase.adenosine 5'-phosphosulfate complex does not serve as a substrate for adenosine 5'-phosphosulfate kinase.

I. H. Segel, F. Renosto, R. L. Martin, 1989, The Journal of biological chemistry.

ATP sulfurylase-dependent assays for inorganic pyrophosphate: applications to determining the equilibrium constant and reverse direction kinetics of the pyrophosphatase reaction, magnesium binding to orthophosphate, and unknown concentrations of pyrophosphate.

I. H. Segel, F. Renosto, L. Daley, 1986, Analytical biochemistry.

Adenosinetriphosphate sulfurylase from Penicillium chrysogenum: steady-state kinetics of the forward and reverse reactions, alternative substrate kinetics, and equilibrium binding studies.

I. H. Segel, F. Renosto, P. Seubert, 1985, Archives of biochemistry and biophysics.

Adenosine 5'-phosphosulfate kinase from Penicillium chrysogenum. Purification and kinetic characterization.

I. H. Segel, F. Renosto, P. Seubert, 1984, The Journal of biological chemistry.

ATP sulfurylase from trophosome tissue of Riftia pachyptila (hydrothermal vent tube worm).

I. H. Segel, D. Nelson, F. Renosto, 1991, Archives of biochemistry and biophysics.

Rat liver ATP-sulfurylase: purification, kinetic characterization, and interaction with arsenate, selenate, phosphate, and other inorganic oxyanions.

I. H. Segel, S. Jain, L. Chen, 1989, Archives of biochemistry and biophysics.

ATP sulfurylase from Penicillium chrysogenum: measurements of the true specific activity of an enzyme subject to potent product inhibition and a reassessment of the kinetic mechanism.

I. H. Segel, F. Renosto, P. Seubert, 1983, Archives of biochemistry and biophysics.

Kinetics of enzymes subject to very strong product inhibition: analysis using simplified integrated rate equations and average velocities.

I. H. Segel, J. Peschon, N. Schmidt, 1983, Journal of theoretical biology.

ATP Sulfurylase from Penicillium chrysogenum: Is the Internal Level of the Enzyme Sufficient to Account for the Rate of Sulfate Utilization?

I. H. Segel, J. Farley, C. Chandler, 1979, Journal of bacteriology.

ATPSulfurylase fromPenicillium chrysogenum: Isthe Internal Level oftheEnzymeSufficient toAccount forthe RateofSulfate Utilization?t

I. H. Segel, J. Farley, 1979 .

ATP sulfurylase from higher plants: kinetic and structural characterization of the chloroplast and cytosol enzymes from spinach leaf.

H. C. Patel, I. H. Segel, F. Renosto, 1993, Archives of biochemistry and biophysics.

INTERMEDIATES IN INORGANIC SULFATE UTILIZATION BY PENICILLIUM CHRYSOGENUM.

I. H. Segel, M. J. Johnson, 1963, Archives of biochemistry and biophysics.

Nitrate reductase from Penicillium chrysogenum: the reduced flavin-adenine dinucleotide-dependent reaction.

I. H. Segel, F. Renosto, N. Schmidt, 1982, Archives of biochemistry and biophysics.

Regulation of Nitrate Uptake in Penicillium chrysogenum

I. H. Segel, J. Livoni, J. Goldsmith, 1973 .

Control of the general amino acid permease of Penicillium chrysogenum by transinhibition and turnover.

I. H. Segel, D. R. Hunter, Douglas R. Hunter, 1973, Archives of biochemistry and biophysics.

Regulation of sulfate transport in filamentous fungi.

I. H. Segel, P. Somerfield, D. Bradley, 1970, Plant physiology.

Independent regulation of cysteine and cystine transport in Penicillium chrysogenum.

I. H. Segel, G. Skye, 1970, Archives of biochemistry and biophysics.

Nitrate reductase from Penicillium chrysogenum: kinetic mechanism at sub-optimum pH.

I. H. Segel, F. Renosto, N. Schmidt, 1982, Biochemical and biophysical research communications.

Nitrate reductase from Penicillium chrysogenum. Purification and kinetic mechanism.

I. H. Segel, F. Renosto, D. Ornitz, 1981, The Journal of biological chemistry.

Kinetic analysis of active membrane transport systems: equations for net velocity and isotope exchange.

I. H. Segel, J. Cuppoletti, John Cuppoletti, 1975, Journal of theoretical biology.

ACCUMULATION OF INTRACELLULAR INORGANIC SULFATE BY PENICILLIUM CHRYSOGENUM

I. H. Segel, M. J. Johnson, 1961, Journal of bacteriology.

ATP-Sulfurylase From Penicillivm Chbysogenum. I. Purification and Characterization

I. H. Segel, J. Tweedie, 1971 .

Crystal structure of ATP sulfurylase from the bacterial symbiont of the hydrothermal vent tubeworm Riftia pachyptila.

I. MacRae, I. H. Segel, A. Fisher, 2001, Biochemistry.

Glycogen phosphorylase of

I. H. Segel, D. Shepherd, Deborah M. Shepherd, 1969 .

Interaction of cyclic adenosine 3':5'-monophosphate with protein kinase. Equilibrium binding models.

I. H. Segel, J. Ogez, 1976, The Journal of biological chemistry.

Purification and properties of glycogen phosphorylase from Escherichia coli.

I. H. Segel, I H Segel, G. S. Chen, 1968, Archives of biochemistry and biophysics.

Synthesis and Metabolism of Quinolinic Acid Ring Labeled with Tritium.∗

I. H. Segel, L. Hankes, 1957, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems

I. H. Segel, 1975 .

Transinhibition kinetics of the sulfate transport system ofPenicillium notatum: Analysis based on an iso Uni Uni velocity equation

I. H. Segel, J. Cuppoletti, 1974, The Journal of Membrane Biology.

Comparative stability and catalytic and chemical properties of the sulfate-activating enzymes from Penicillium chrysogenum (mesophile) and Penicillium duponti (thermophile)

I. H. Segel, E. Re, J. Mazer, 1985, Journal of bacteriology.