Michael V. Cohen

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Adenosine: trigger and mediator of cardioprotection

Michael V. Cohen, J. Downey, M. Cohen, 2008, Basic Research in Cardiology.

CHAPTER 50 – Ischemic Preconditioning: Description, Mechanism, and Significance

Michael V. Cohen, J. Downey, M. Cohen, 2001 .

Protein Kinase C- ξ is Responsible for the Protection of Preconditioning in Rabbit Cardiomyocytes

Michael V. Cohen, J. Downey, D. Mochly‐Rosen, 1999 .

VENOUS LEVEL COLLATERALS IN THE CORONARY SYSTEM

Michael V. Cohen, J. Downey, M. Cohen, 1992 .

Introduction to a mechanism for automated myocardium boundary detection with displacement encoding with stimulated echoes (DENSE)

Michael V. Cohen, X. Zhong, J. Kar, 2018, The British journal of radiology.

Making the heart resistant to infarction: how can we further decrease infarct size?

Michael V. Cohen, J. Downey, T. Krieg, 2008, Frontiers in bioscience : a journal and virtual library.

Dose-response relationships of the protective and antiprotective effects of acute ethanol exposure in isolated rabbit hearts.

Michael V. Cohen, J. Downey, M. Krenz, 2002, Heart disease.

Acetylcholine leads to free radical production dependent on K(ATP) channels, G(i) proteins, phosphatidylinositol 3-kinase and tyrosine kinase.

Michael V. Cohen, J. Downey, O. Oldenburg, 2002, Cardiovascular research.

Acetylcholine but not adenosine triggers preconditioning through PI3-kinase and a tyrosine kinase.

Michael V. Cohen, J. Downey, Q. Qin, 2003, American journal of physiology. Heart and circulatory physiology.

Can post-chemotherapy cardiotoxicity be detected in long-term survivors of breast cancer via comprehensive 3D left-ventricular contractility (strain) analysis?

Michael V. Cohen, J. Kar, M. Figarola, 2019, Magnetic resonance imaging.

Fully automated and comprehensive MRI-based Left-Ventricular contractility analysis in Post-Chemotherapy breast cancer patients.

Michael V. Cohen, M. Figarola, Samuel P McQuiston, 2020, The British journal of radiology.

The impact of irreproducibility and competing protection from P2Y12 antagonists on the discovery of cardioprotective interventions

Michael V. Cohen, J. Downey, M. Cohen, 2017, Basic Research in Cardiology.

Signalling pathways and mechanisms of protection in pre‐ and postconditioning: historical perspective and lessons for the future

Michael V. Cohen, J. Downey, M. Cohen, 2015, British journal of pharmacology.

What is Wrong With Cardiac Conditioning? We May be Shooting at Moving Targets

Michael V. Cohen, J. Downey, N. Dagres, 2015, Journal of cardiovascular pharmacology and therapeutics.

Pathophysiology of Myocardial Reperfusion Injury

Michael V. Cohen, J. Downey, M. Cohen, 2012 .

A2B or not 2B: that is the question

Michael V. Cohen, J. Downey, 2012 .

Ischemic postconditioning: from receptor to end-effector.

Michael V. Cohen, J. Downey, M. Cohen, 2011, Antioxidants & redox signaling.

Is It Time to Translate Ischemic Preconditioning’s Mechanism of Cardioprotection into Clinical Practice?

Michael V. Cohen, J. Downey, M. Cohen, 2011, Journal of cardiovascular pharmacology and therapeutics.

Mechanism of Cardioprotection by Early Ischemic Preconditioning

Michael V. Cohen, J. Downey, Xiulan Yang, 2010, Cardiovascular Drugs and Therapy.

Why do we still not have cardioprotective drugs?

Michael V. Cohen, J. Downey, M. Cohen, 2009, Circulation journal : official journal of the Japanese Circulation Society.

Modulation of receptor sensitivity: possible therapeutic target?

Michael V. Cohen, J. Downey, M. Cohen, 2009, British journal of pharmacology.

O-linked beta-N-acetylglucosamine: a new piece of the cardioprotection puzzle?

Michael V. Cohen, J. Downey, M. Cohen, 2008, Circulation research.

Adenosine at reperfusion: a conundrum ready to be resolved.

Michael V. Cohen, J. Downey, M. Cohen, 2009, Journal of the American College of Cardiology.

cGMP signalling in pre- and post-conditioning: the role of mitochondria.

Michael V. Cohen, J. Downey, S. Pierre, 2008, Cardiovascular research.

Free radicals in the heart: friend or foe?

Michael V. Cohen, J. Downey, M. Cohen, 2008, Expert review of cardiovascular therapy.

Acidosis, oxygen, and interference with mitochondrial permeability transition pore formation in the early minutes of reperfusion are critical to postconditioning’s success

Michael V. Cohen, J. Downey, Xi-ming Yang, 2008, Basic Research in Cardiology.

Signaling pathways in ischemic preconditioning

Michael V. Cohen, J. Downey, Amanda M. Davis, 2007, Heart Failure Reviews.

Bypassing big pharma.

Michael V. Cohen, J. Downey, M. Cohen, 2007, Circulation.

Reducing infarct size in the setting of acute myocardial infarction.

Michael V. Cohen, J. Downey, M. Cohen, 2006, Progress in cardiovascular diseases.

Nitric oxide is a preconditioning mimetic and cardioprotectant and is the basis of many available infarct-sparing strategies.

Michael V. Cohen, J. Downey, Xi-ming Yang, 2006, Cardiovascular research.

We think we see a pattern emerging here.

Michael V. Cohen, J. Downey, M. Cohen, 2005, Circulation.

Unraveling the mysteries of classical preconditioning.

Michael V. Cohen, J. Downey, M. Cohen, 2005, Journal of molecular and cellular cardiology.

Cardioprotection With Adenosine A2 Receptor Activation at Reperfusion

Michael V. Cohen, J. Downey, R. Mueller, 2005, Journal of cardiovascular pharmacology.

Mechanisms of acetylcholine- and bradykinin-induced preconditioning.

Michael V. Cohen, J. Downey, S. Critz, 2005, Vascular pharmacology.

Protective and anti-protective effects of acute ethanol exposure in myocardial ischemia/reperfusion.

Michael V. Cohen, J. Downey, M. Krenz, 2004, Pathophysiology : the official journal of the International Society for Pathophysiology.

Efficacy of preconditioning should be gauged by reduction of infarction

Michael V. Cohen, 2004, British journal of pharmacology.

Mitochondria and their role in preconditioning's trigger phase

Michael V. Cohen, J. Downey, T. Krieg, 2003, Basic Research in Cardiology.

Focus on the Mitochondrion Mitochondrial K ATP channels in preconditioning

Michael V. Cohen, J. Downey, O. Oldenburg, 2003 .

P1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species resulting in cardioprotection of rabbit hearts.

Michael V. Cohen, J. Downey, G. Grover, 2003, Journal of molecular and cellular cardiology.

CGX-1051, A Peptide from Conus Snail Venom, Attenuates Infarction in Rabbit Hearts When Administered at Reperfusion

Michael V. Cohen, J. Downey, Guang S. Liu, 2003, Journal of cardiovascular pharmacology.

Mitochondrial KATP channels in preconditioning

Michael V. Cohen, J. Downey, O. Oldenburg, 2003 .

Preconditioning one myocardial region does not neccessarily precondition the whole rabbit heart

Michael V. Cohen, J. Downey, A. Nakano, 2002, Basic Research in Cardiology.

The relative order of mK(ATP) channels, free radicals and p38 MAPK in preconditioning's protective pathway in rat heart.

Michael V. Cohen, J. Downey, S. Critz, 2002, Cardiovascular research.

Xanthine oxidase contributes to preconditioning's preservation of left ventricular developed pressure in isolated rat heart: developed pressure may not be an appropriate end-point for studies of preconditioning

Michael V. Cohen, J. Downey, C. Morales, 2002, Basic Research in Cardiology.

Protection From AMP 579 Can Be Added to That From Either Cariporide or Ischemic Preconditioning in Ischemic Rabbit Heart

Michael V. Cohen, J. Downey, Zhe Jiao, 2002, Journal of cardiovascular pharmacology.

Mitochondrial K(ATP) channels: role in cardioprotection.

Michael V. Cohen, J. Downey, D. Yellon, 2002, Cardiovascular research.

Do mitochondrial KATP channels serve as triggers rather than end-effectors of ischemic preconditioning's protection?

Michael V. Cohen, J. Downey, 2000, Basic Research in Cardiology.

Volatile Anesthetics Protect the Ischemic Rabbit Myocardium from Infarction

Michael V. Cohen, J. Downey, D. Cope, 1997, Anesthesiology.

Do Adenosine A3 Receptors Cause Preconditioning

Michael V. Cohen, J. Downey, Guang S. Liu, 1996 .

Role of Adenosine in the Phenomenon of Ischemic Preconditioning

Michael V. Cohen, J. Downey, M. Cohen, 1995 .

28 DO ADENOSINE A:J RECEPTORS CAUSE PRECONDmONING?

Michael V. Cohen, J. Downey, Guang S. Liu, 1995 .

Adenosine and Opioid Receptors Do Not Trigger the Cardioprotective Effect of Mild Hypothermia

Michael V. Cohen, J. Downey, B. Ghaleh, 2012, Journal of cardiovascular pharmacology and therapeutics.

Cardioprotection by mild hypothermia during ischemia involves preservation of ERK activity

Michael V. Cohen, J. Downey, Xiulan Yang, 2011, Basic Research in Cardiology.

Combined Cardioprotectant and Antithrombotic Actions of Platelet P2Y12 Receptor Antagonists in Acute Coronary Syndrome

Michael V. Cohen, J. Downey, M. Cohen, 2014, Journal of cardiovascular pharmacology and therapeutics.

Platelet P2Y12 Blockers Confer Direct Postconditioning-Like Protection in Reperfused Rabbit Hearts

Michael V. Cohen, J. Downey, Yongge Liu, 2013, Journal of cardiovascular pharmacology and therapeutics.

Animal models for the study of myocardial protection against ischemia

Michael V. Cohen, J. Downey, S. Philipp, 2005 .

Does mild hypothermia protect against reperfusion injury? The debate continues

Michael V. Cohen, J. Downey, R. Tissier, 2011, Basic Research in Cardiology.

Rapid cooling preserves the ischaemic myocardium against mitochondrial damage and left ventricular dysfunction.

Michael V. Cohen, J. Downey, J. Dubois-Randé, 2009, Cardiovascular research.

Myocardial hypothermia preserves mitochondrial and post-ischemic regional left ventricular functions in rabbits

Michael V. Cohen, J. Downey, J. Dubois-Randé, 2009 .

S-T segment voltage during sequential coronary occlusions is an unreliable marker of preconditioning.

Michael V. Cohen, J. Downey, S. Critz, 1999, American journal of physiology. Heart and circulatory physiology.