Jianhua Shen

发表

Dynamic mechanism for the autophosphorylation of CheA histidine kinase: molecular dynamics simulations.

Jian Zhang, Xiaomin Luo, Weiliang Zhu, 2005, Journal of the American Chemical Society.

Virtual screening on natural products for discovering active compounds and target information.

Kaixian Chen, Hualiang Jiang, Jianhua Shen, 2003, Current medicinal chemistry.

Focused combinatorial library design based on structural diversity, druglikeness and binding affinity score.

Jian Zhang, Xiaomin Luo, Weiliang Zhu, 2005, Journal of combinatorial chemistry.

Strategy for discovering chemical inhibitors of human cyclophilin a: focused library design, virtual screening, chemical synthesis and bioassay.

Jian Zhang, Xiaomin Luo, Weiliang Zhu, 2006, Journal of combinatorial chemistry.

Discovering Severe Acute Respiratory Syndrome Coronavirus 3CL Protease Inhibitors: Virtual Screening, Surface Plasmon Resonance, and Fluorescence Resonance Energy Transfer Assays

Xu Shen, Jianhua Shen, Shuai Chen, 2006, SLAS Discovery.

Molecular docking and 3D-QSAR studies on gag peptide analogue inhibitors interacting with human cyclophilin A.

Xiaomin Luo, Kaixian Chen, Hualiang Jiang, 2002, Journal of Medicinal Chemistry.

Steered molecular dynamics simulation on the binding of NNRTI to HIV-1 RT.

Xiaomin Luo, Kaixian Chen, Hualiang Jiang, 2003, Biophysical journal.

Brownian dynamics simulations of the recognition of the scorpion toxin maurotoxin with the voltage-gated potassium ion channels.

Xiaomin Luo, Kaixian Chen, Hualiang Jiang, 2002, Biophysical journal.

Conformational transition of amyloid β-peptide

Jianpeng Ma, Weiliang Zhu, Hualiang Jiang, 2005 .

In vitro biochemical and thermodynamic characterization of nucleocapsid protein of SARS

Fei Ye, Jing Chen, Xu Shen, 2004, Biophysical Chemistry.

Interaction Models of a Series of Oxadiazole-Substituted α-Isopropoxy Phenylpropanoic Acids Against PPARα and PPARγ: Molecular Modeling and Comparative Molecular Similarity Indices Analysis Studies

Kaixian Chen, Hualiang Jiang, Jianhua Shen, 2009 .

Molecular Dynamics Simulations on SDF-1α: Binding with CXCR4 Receptor

Lingling Shen, Gang Pei, Hualiang Jiang, 2003 .

Structure-based discovery of potassium channel blockers from natural products: virtual screening and electrophysiological assay testing.

Yang Li, Jianmin Yue, Suxin Zheng, 2003, Chemistry & biology.

Cinanserin Is an Inhibitor of the 3C-Like Proteinase of Severe Acute Respiratory Syndrome Coronavirus and Strongly Reduces Virus Replication In Vitro

Christian Drosten, Burkhard Ludewig, Elke Scandella, 2005, Journal of Virology.

Nucleocapsid protein of SARS coronavirus tightly binds to human cyclophilin A

Cheng Luo, Jingkang Shen, Suxin Zheng, 2004, Biochemical and Biophysical Research Communications - BBRC.

Molecular docking and 3D QSAR studies on 1-amino-2-phenyl-4-(piperidin-1-yl)-butanes based on the structural modeling of human CCR5 receptor.

Cheng Luo, Hong Liu, Hualiang Jiang, 2004, Bioorganic & medicinal chemistry.

Ligand‐binding regulation of LXR/RXR and LXR/PPAR heterodimerizations: SPR technology‐based kinetic analysis correlated with molecular dynamics simulation

Kaixian Chen, Hualiang Jiang, Jianhua Shen, 2005, Protein science : a publication of the Protein Society.

Binding analyses between Human PPARgamma-LBD and ligands.

Kaixian Chen, Hualiang Jiang, Jianhua Shen, 2004, European journal of biochemistry.

Lipoprotein‐associated phospholipase A2: The story continues

Jianhua Shen, F. Huang, Kai Wang, 2019, Medicinal research reviews.

Small envelope protein E of SARS: cloning, expression, purification, CD determination, and bioinformatics analysis.

Jing Chen, Xu Shen, Hai-Bin Luo, 2003, Acta pharmacologica Sinica.

An overall picture of SARS coronavirus (SARS-CoV) genome-encoded major proteins: structures, functions and drug development.

Weiliang Zhu, Kaixian Chen, Hualiang Jiang, 2006, Current pharmaceutical design.

Molecular cloning, expression, purification, and mass spectrometric characterization of 3C-like protease of SARS coronavirus

Kaixian Chen, Hualiang Jiang, Jianhua Shen, 2003, Protein Expression and Purification.

Inhibitory mode of 1,5-diarylpyrazole derivatives against cyclooxygenase-2 and cyclooxygenase-1: molecular docking and 3D QSAR analyses.

Bing Xiong, Kaixian Chen, Jianhua Shen, 2002, Journal of medicinal chemistry.

Discovery of Potent and Orally Active Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitors as a Potential Therapy for Diabetic Macular Edema.

Jianhua Shen, Yi-ping Wang, Kai Wang, 2016, Journal of medicinal chemistry.

TGR5 agonist ameliorates insulin resistance in the skeletal muscles and improves glucose homeostasis in diabetic mice.

Jianhua Shen, Suling Huang, Sha Ma, 2019, Metabolism: clinical and experimental.

The conserved residue Phe273(282) of PPARα(γ), beyond the ligand-binding site, functions in binding affinity through solvation effect

Fei Ye, Xu Shen, Hualiang Jiang, 2005 .

4-(Phenylsulfonamidomethyl)benzamides as potent and selective inhibitors of the 11beta-hydroxysteroid dehydrogenase type 1 with efficacy in diabetic ob/ob mice.

Jianhua Shen, Huaiyu Yang, Lili Du, 2009, Bioorganic & medicinal chemistry letters.

Structure-based de novo design, synthesis, and biological evaluation of the indole-based PPARgamma ligands (I).

Xu Shen, Ren Wen, Jianhua Shen, 2006, Bioorganic & medicinal chemistry letters.

Design, synthesis and structure−activity relationship studies of GPR40 agonists containing amide linker

Jianhua Shen, Kai Wang, Meng-meng Ning, 2018 .

Pyrazolidine-3,5-dione derivatives as potent non-steroidal agonists of farnesoid X receptor: virtual screening, synthesis, and biological evaluation.

Kaixian Chen, Hualiang Jiang, Jianhua Shen, 2008, Bioorganic & medicinal chemistry letters.

TarFisDock: a web server for identifying drug targets with docking approach

Xiaomin Luo, Kun Yang, Weiliang Zhu, 2006, Nucleic Acids Res..

Structure-based drug design of a novel family of chalcones as PPARα agonists: virtual screening, synthesis, and biological activities in vitro

Jianhua Shen, Xia Li, Yang-liang Ye, 2007, Acta Pharmacologica Sinica.

Design, synthesis, and antidiabetic activity of 4-phenoxynicotinamide and 4-phenoxypyrimidine-5-carboxamide derivatives as potent and orally efficacious TGR5 agonists.

Jianhua Shen, Xiaoyan Chen, Meng-meng Ning, 2012, Journal of medicinal chemistry.

Design and synthesis of imidazole and triazole derivatives as Lp-PLA₂ inhibitors and the unexpected discovery of highly potent quaternary ammonium salts.

Wei Zhang, Jianhua Shen, Yang Liu, 2013, Bioorganic & medicinal chemistry letters.

Identification of Highly Selective Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitors by a Covalent-Fragment-Based Approach.

Yechun Xu, Jianhua Shen, Hu Zhou, 2020, Journal of medicinal chemistry.

Discovery of novel dual functional agent as PPARgamma agonist and 11beta-HSD1 inhibitor for the treatment of diabetes.

Jianhua Shen, Min-li Chen, Yang-liang Ye, 2009, Bioorganic & medicinal chemistry.

Pyrimidinyl-arylpropionic acid derivatives: viable resources in the development of new antineoplastic agents

Jianhua Shen, B. Dai, C. Mei, 2010, Investigational New Drugs.

Antitumor activity of a novel series of α-aryloxy-α-methylhydrocinnamic acid derivatives as PPAR gamma agonists against a panel of human cancer cell lines

Jianhua Shen, B. Dai, C. Mei, 2009, Investigational New Drugs.

Intestinally-targeted TGR5 agonists equipped with quaternary ammonium have an improved hypoglycemic effect and reduced gallbladder filling effect

Jianhua Shen, Kai Wang, Meng-meng Ning, 2016, Scientific Reports.

Identification and Evaluation of Coronavirus Replicase Inhibitors Using a Replicon Cell Line

Xiaomin Luo, Hualiang Jiang, Jianhua Shen, 2006, Advances in experimental medicine and biology.

Discovery of Highly Polar β-homophenylalanine Derivatives as Non-systemic Intestine-Targeted Dipeptidyl Peptidase IV Inhibitors.

Jianhua Shen, Jia Liu, F. Huang, 2019, Journal of medicinal chemistry.

SL010110, a lead compound, inhibits gluconeogenesis via SIRT2-p300-mediated PEPCK1 degradation and improves glucose homeostasis in diabetic mice

Jianhua Shen, Suling Huang, Jia Liu, 2021, Acta Pharmacologica Sinica.

Inhibition of Lipoprotein-Associated Phospholipase A2 Ameliorates Inflammation and Decreases Atherosclerotic Plaque Formation in ApoE-Deficient Mice

Jianhua Shen, Jie Li, H. Yan, 2011, PloS one.

Synthesis of AC1903 analogs as potent transient receptor potential canonical channel 4/5 inhibitors and biological evaluation

Jianhua Shen, Zhengyu Cao, H. Tian, 2022, Bioorganic & Medicinal Chemistry.

Design and exploration of gut-restricted bifunctional molecule with TGR5 agonistic and DPP4 inhibitory effects for treating ulcerative colitis.

Jianhua Shen, H. Qu, Kai Wang, 2022, European journal of medicinal chemistry.

Derivatives of (phenylsulfonamido-methyl)nicotine and (phenylsulfonamido-methyl)thiazole as novel 11β-hydroxysteroid dehydrogenase type 1 inhibitors: synthesis and biological activities in vitro

Jianhua Shen, Yang Zhou, Y. Leng, 2009, Acta Pharmacologica Sinica.

Steered molecular dynamics simulations of protein-ligand interactions

Xiaomin Luo, Kaixian Chen, Hualiang Jiang, 2004 .

Design of G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) soft drugs with reduced gallbladder-filling effects.

Jianhua Shen, Meng-meng Ning, Yang-liang Ye, 2020, European journal of medicinal chemistry.

Discovery of novel ketoxime ether derivatives with potent FXR agonistic activity, oral effectiveness and high liver/blood ratio.

Jianhua Shen, Hongyi Yan, Meng-meng Ning, 2021, Bioorganic & medicinal chemistry.

Quantification of microbiota-related phenols and aromatic acids in mouse feces of a diabetic nephropathy model by simultaneous BDAPE derivatization using ultra-performance liquid chromatography-tandem mass spectrometry

Jianhua Shen, Hui Xu, Jia Liu, 2020, Analytical and Bioanalytical Chemistry.

POSSIBLE PATHWAY(S) OF TESTOSTERONE EGRESS FROM THE ACTIVE SITE OF CYTOCHROME P450 2B1: A STEERED MOLECULAR DYNAMICS SIMULATION

Weihua Li, Frauke Gräter, Hualiang Jiang, 2005, Drug Metabolism and Disposition.

pH-dependent Conformational Flexibility of the SARS-CoV Main Proteinase (Mpro) Dimer: Molecular Dynamics Simulations and Multiple X-ray Structure Analyses

Kaixian Chen, Hualiang Jiang, Yechun Xu, 2005, Journal of Molecular Biology.

New selective O-debenzylation of phenol with Mg/MeOH

Hualiang Jiang, Jianhua Shen, Xu Zhang, 2005 .

Microwave‐Assisted Synthesis of 2‐Amino‐thiophene‐3‐Carboxylic Derivatives Under Solvent‐Free Conditions

Hualiang Jiang, Jianhua Shen, Hong Liu, 2005 .

4-Benzofuranyloxynicotinamide derivatives are novel potent and orally available TGR5 agonists.

Jianhua Shen, Junjie Zhu, Jia Liu, 2014, European journal of medicinal chemistry.

Discovery of a Novel Series of Imidazo[1,2-a]pyrimidine Derivatives as Potent and Orally Bioavailable Lipoprotein-Associated Phospholipase A2 Inhibitors.

Yechun Xu, Jianhua Shen, Xiaojing Yuan, 2015, Journal of medicinal chemistry.

Molecular docking and 3-D-QSAR studies on the possible antimalarial mechanism of artemisinin analogues.

Weiliang Zhu, Jiande Gu, Hualiang Jiang, 2002, Bioorganic & medicinal chemistry.

New p-methylsulfonamido phenylethylamine analogues as class III antiarrhythmic agents: design, synthesis, biological assay, and 3D-QSAR analysis.

Xiaomin Luo, Kaixian Chen, Hualiang Jiang, 2002, Journal of medicinal chemistry.

Differentiation of Cation-π Bonding from Cation-π Intermolecular Interactions: A Quantum Chemistry Study Using Density-Functional Theory and Morokuma Decomposition Methods

Weiliang Zhu, Kaixian Chen, Hualiang Jiang, 2003 .

New Selective O‐Debenzylation of Phenol with Mg/MeOH.

Hualiang Jiang, Jianhua Shen, Xu Zhang, 2005 .

Microwave‐Assisted Synthesis of 2‐Aminothiophene‐3‐carboxylic Derivatives under Solvent‐Free Conditions.

Hualiang Jiang, Jianhua Shen, Hong Liu, 2005 .

A density-functional study of the mechanism for the diastereoselective epoxidation of chiral allylic alcohols by the titanium peroxy complexes.

Hualiang Jiang, Jianhua Shen, Xiao-min Luo, 2002, The Journal of organic chemistry.

Dopamine D1 receptor agonist and D2 receptor antagonist effects of the natural product (-)-stepholidine: molecular modeling and dynamics simulations.

Weiliang Zhu, Kunqian Yu, Hualiang Jiang, 2007, Biophysical journal.

Putative hAPN receptor binding sites in SARS_CoV spike protein.

Cheng Luo, Guo-Ping Zhao, Zong-Ming Guo, 2003, Acta pharmacologica Sinica.

N-methylformamide-benzene complex as a prototypical peptide N-H...pi hydrogen-bonded system: density functional theory and MP2 studies.

Weiliang Zhu, Hualiang Jiang, Kaixian Chen, 2003, The Journal of organic chemistry.

Swietenia mahagony extract shows agonistic activity to PPAR γ and gives ameliorative effects on diabetic db/db mice

Hualiang Jiang, Jianhua Shen, Xu Shen, 2005, Acta Pharmacologica Sinica.

Discovery of novel inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 by docking and pharmacophore modeling.

Ying Leng, Jianhua Shen, Jianhua Shen, 2008, Bioorganic & medicinal chemistry letters.

Emodin, a natural product, selectively inhibits 11β‐hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet‐induced obese mice

Jianhua Shen, Suling Huang, Song Zhang, 2010, British journal of pharmacology.

Determining PPARγ-ligand binding affinity using fluorescent assay with cis-parinaric acid as a probe

Kaixian Chen, Hualiang Jiang, Jianhua Shen, 2005 .

Additivity of Cation−π Interactions: An ab Initio Computational Study on π−Cation−π Sandwich Complexes

Xiaomin Luo, Weiliang Zhu, Kaixian Chen, 2004 .

Structural insights into the effect of isonucleosides on B-DNA duplexes using molecular-dynamics simulations

Hualiang Jiang, Jianhua Shen, Suxin Zheng, 2006, Journal of molecular modeling.

Design, Synthesis, and Structure–Activity Relationships of 3,4,5‐Trisubstituted 4,5‐Dihydro‐1,2,4‐oxadiazoles as TGR5 Agonists

Ying Feng, Junjie Zhu, Ying Leng, 2013, ChemMedChem.

The Multiplicity, Strength, and Nature of the Interaction of Nucleobases with Alkaline and Alkaline Earth Metal Cations: A Density Functional Theory Investigation

Xiaomin Luo, Weiliang Zhu, Kaixian Chen, 2004 .

The Dipeptide H‐Trp‐Glu‐OH Shows Highly Antagonistic Activity against PPARγ: Bioassay with Molecular Modeling Simulation

Fei Ye, Xu Shen, Hai-Bin Luo, 2006, Chembiochem : a European journal of chemical biology.

Carbocation–π interaction with Car–Parrinello molecular dynamics: Ab initio molecular dynamics investigation of complex of methyl cation with benzene

Hualiang Jiang, Jianhua Shen, Rongjian Sa, 2007 .

A yeast two-hybrid technology-based system for the discovery of PPARgamma agonist and antagonist.

Hualiang Jiang, Jianhua Shen, Xu Shen, 2004, Analytical biochemistry.

Mechanically induced titin kinase activation studied by force-probe molecular dynamics simulations.

Hualiang Jiang, Jianhua Shen, H. Grubmüller, 2005, Biophysical journal.

Molecular docking and 3D-QSAR studies on the binding mechanism of statine-based peptidomimetics with β-secretase

Zhili Zuo, Weiliang Zhu, Xu Shen, 2005 .

Identification of probable genomic packaging signal sequence from SARS-CoV genome by bioinformatics analysis.

Cheng Luo, Guo-Ping Zhao, Zong-Ming Guo, 2003, Acta pharmacologica Sinica.

Phenotypic screening-based drug discovery of furan-2-carboxylic acid derivatives for the amelioration of type 2 diabetes mellitus (T2DM).

Jianhua Shen, Lili Du, Yang-liang Ye, 2023, European journal of medicinal chemistry.

Structure-based virtual screening for identification of novel 11 beta-HSD1 inhibitors

Ying Leng, Jianhua Shen, Jing Chen, 2009 .

Structure-based virtual screening for identification of novel 11beta-HSD1 inhibitors.

Ying Leng, Jianhua Shen, Jianhua Shen, 2009, European journal of medicinal chemistry.

STRUCTURAL FEATURE OF AChE INHIBITOR HUPERZINE B IN NATURE AND IN THE BINDING SITE OF AChE: DENSITY FUNCTIONAL THEORY STUDY COMBINED WITH IR DETERMINATION

Weiliang Zhu, Kaixian Chen, Hualiang Jiang, 2002 .

Simulating the interactions of toxins with K+ channels.

Xiaomin Luo, Kunqian Yu, Kaixian Chen, 2004, Current pharmaceutical design.

Identification of an epitope of SARS-coronavirus nucleocapsid protein

Yuan WANG, Hualiang Jiang, Jianhua Shen, 2003, Cell Research.

Design, synthesis and biological evaluation of a novel class of potent TGR5 agonists based on a 4-phenyl pyridine scaffold.

Jianhua Shen, Junjie Zhu, Guoyu Pan, 2013, European journal of medicinal chemistry.

Molecular dynamics simulations of interaction between protein-tyrosine phosphatase 1B and a bidentate inhibitor

Jianhua Shen, Xu Shen, Guixia Liu, 2006, Acta Pharmacologica Sinica.

Quantum Chemistry Study on the Interaction of the Exogenous Ligands and the Catalytic Zinc Ion in Matrix Metalloproteinases

Weiliang Zhu, Jiande Gu, Xin Li, 2002 .

The interaction model between metal cation and tropylium: a quantum chemistry predication

Xiaomin Luo, Weiliang Zhu, Kaixian Chen, 2002 .

Towards discovering dual functional inhibitors against both wild type and K103N mutant HIV-1 reverse transcriptases: molecular docking and QSAR studies on 4,1-benzoxazepinone analogues

Xiaomin Luo, Weiliang Zhu, Li Du, 2006, J. Comput. Aided Mol. Des..

Molecular docking and 3D-QSAR studies on the binding mechanism of statine-based peptidomimetics with beta-secretase.

Xiaomin Luo, Weiliang Zhu, Kaixian Chen, 2005, Bioorganic & Medicinal Chemistry.

Severe Acute Respiratory Syndrome Coronavirus 3C-like Proteinase N Terminus Is Indispensable for Proteolytic Activity but Not for Enzyme Dimerization

Li Du, Jing Chen, Xu Shen, 2005, Journal of Biological Chemistry.

Structure-Guided Discovery of Novel, Potent, and Orally Bioavailable Inhibitors of Lipoprotein-Associated Phospholipase A2.

Qiufeng Liu, Jianhua Shen, Yechun Xu, 2017, Journal of medicinal chemistry.

Structural and Thermodynamic Characterization of Protein-Ligand Interactions Formed between Lipoprotein-Associated Phospholipase A2 and Inhibitors.

Yechun Xu, Jianhua Shen, Qiu-feng Liu, 2016, Journal of medicinal chemistry.

Triazole derivatives: a series of Darapladib analogues as orally active Lp-PLA2 inhibitors.

Wei Zhang, Jianhua Shen, Yi-ping Wang, 2013, Bioorganic & medicinal chemistry letters.

The type IA topoisomerase catalytic cycle: A normal mode analysis and molecular dynamics simulation

Xiaomin Luo, Jianhua Shen, Hong Liu, 2008, Proteins.

OL3, a novel low-absorbed TGR5 agonist with reduced side effects, lowered blood glucose via dual actions on TGR5 activation and DPP-4 inhibition

Jianhua Shen, Sha Ma, Meng-meng Ning, 2016, Acta Pharmacologica Sinica.

Molecular Dynamics Simulations on SDF-1 a : Binding with CXCR 4 Receptor

Xiaomin Luo, Kaixian Chen, Hualiang Jiang, 2008 .

Discovery of Intestinal Targeted TGR5 Agonists for the Treatment of Type 2 Diabetes.

Jianhua Shen, Meng-meng Ning, Yang-liang Ye, 2015, Journal of medicinal chemistry.

Linderane Suppresses Hepatic Gluconeogenesis by Inhibiting the cAMP/PKA/CREB Pathway Through Indirect Activation of PDE 3 via ERK/STAT3

Jianhua Shen, Wei Xie, Yang-liang Ye, 2018, Front. Pharmacol..

Computational simulations of interactions of scorpion toxins with the voltage-gated potassium ion channel.

Xiaomin Luo, Kunqian Yu, Hualiang Jiang, 2004, Biophysical journal.

Discovery of pyridazinone analogs as potent transient receptor potential canonical channel 5 inhibitors.

Jianhua Shen, Zhengyu Cao, H. Tian, 2022, Bioorganic & medicinal chemistry letters.

Steered molecular dynamics simulations on the "tail helix latch" hypothesis in the gelsolin activation process.

Xiaomin Luo, Kaixian Chen, Hualiang Jiang, 2002, Biophysical journal.

Discovering potassium channel blockers from synthetic compound database by using structure-based virtual screening in conjunction with electrophysiological assay.

Weiliang Zhu, Yang Li, Suxin Zheng, 2007, Journal of medicinal chemistry.

Synthesis and evaluation of piperidine urea derivatives as efficacious 11β-hydroxysteroid dehydrogenase type 1 inhibitors in diabetic ob/ob mice.

Jianhua Shen, Meng-meng Ning, Y. Leng, 2012, Bioorganic & medicinal chemistry letters.

How does huperzine A enter and leave the binding gorge of acetylcholinesterase? Steered molecular dynamics simulations.

Joel L Sussman, Hualiang Jiang, Kaixian Chen, 2003, Journal of the American Chemical Society.

Computational analysis of molecular basis of 1:1 interactions of NRG‐1β wild‐type and variants with ErbB3 and ErbB4

Cheng Luo, Mingdong Zhou, Suxin Zheng, 2005, Proteins.

Brownian dynamics simulations of the recognition of the scorpion toxin P05 with the small-conductance calcium-activated potassium channels.

Xiaomin Luo, Kaixian Chen, Hualiang Jiang, 2002, Journal of Molecular Biology.

A 3D model of SARS_CoV 3CL proteinase and its inhibitors design by virtual screening.

Cheng Luo, Jing Chen, Xu Shen, 2003, Acta pharmacologica Sinica.

Conformational transition of amyloid beta-peptide.

Jianpeng Ma, Weiliang Zhu, Hualiang Jiang, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Molecular insight into the interaction between IFABP and PA by using MM-PBSA and alanine scanning methods.

Cheng Luo, Weiliang Zhu, Hanjun Zou, 2007, The journal of physical chemistry. B.

Folding of the SARS coronavirus spike glycoprotein immunological fragment (SARS_S1b): thermodynamic and kinetic investigation correlating with three-dimensional structural modeling.

Hualiang Jiang, Jianhua Shen, Xu Shen, 2005, Biochemistry.

GAsDock: a new approach for rapid flexible docking based on an improved multi-population genetic algorithm.

Honglin Li, Kaixian Chen, Jianhua Shen, 2004, Bioorganic & medicinal chemistry letters.

Antitumor Efficacy of Two Novel Non-Thiazolidinedione Compounds as Peroxisome Proliferator-Activated Receptor-γ Agonists in Human Osteosarcoma Cells in vitro

Jianhua Shen, C. Mei, Xishan Xiong, 2009, Chemotherapy.

Discovery of 4-benzoylpiperidine and 3-(piperidin-4-yl)benzo[d]isoxazole derivatives as potential and selective GlyT1 inhibitors

Jianhua Shen, Xuechu Zhen, G. Lin, 2015 .

Molecular dynamics simulations on SDF-1alpha: binding with CXCR4 receptor.

Lingling Shen, Gang Pei, Hualiang Jiang, 2003, Biophysical journal.

4-(Phenylsulfonamidomethyl)benzamides as Potent and Selective Inhibitors of the 11β-Hydroxysteroid Dehydrogenase Type 1 with Efficacy in Diabetic ob/ob Mice.

Jianhua Shen, Huaiyu Yang, Lili Du, 2009 .

Correction to "Conformational dynamics of the nicotinic acetylcholine receptor channel: a 35-ns molecular dynamics simulation study".

Xiaomin Luo, Kaixian Chen, Hualiang Jiang, 2015, Journal of the American Chemical Society.

Blocking of the nicotinic acetylcholine receptor ion channel by chlorpromazine, a noncompetitive inhibitor: A molecular dynamics simulation study.

Weiliang Zhu, Hualiang Jiang, Kaixian Chen, 2006, The journal of physical chemistry. B.

Discovery of Novel 5,6-Dihydro-1,2,4-triazine Derivatives as Efficacious Glucagon-Like Peptide-1 Receptor Agonists.

Jianhua Shen, Ting Zhao, Shimeng Guo, 2023, Journal of medicinal chemistry.

A conserved and druggable pocket in class B G protein coupled receptors for orally active small molecule agonists

Jianhua Shen, Xinheng He, Junrui Li, 2023, bioRxiv.

Dynamic mechanism of E2020 binding to acetylcholinesterase: a steered molecular dynamics simulation.

Weiliang Zhu, Joel L Sussman, Hualiang Jiang, 2005, The journal of physical chemistry. B.

Conformational flexibility of beta-secretase: molecular dynamics simulation and essential dynamics analysis.

Xu Shen, Kai-Xian Chen, Jianhua Shen, 2004, Acta pharmacologica Sinica.

Antitumor Efficacy of Two Novel Non-Thiazolidinedione Compounds as Peroxisome Proliferator-Activated Receptor-γ Agonists in Human Osteosarcoma Cells in vitro

Jianhua Shen, C. Mei, Xishan Xiong, 2009, Chemotherapy.

Contents Vol. 55, 2009

Jianhua Shen, H. Kayed, J. Kleeff, 2009, Chemotherapy.

Dynamic mechanism of fatty acid transport across cellular membranes through FadL: molecular dynamics simulations.

Xiaomin Luo, Weiliang Zhu, Kaixian Chen, 2008, The journal of physical chemistry. B.

Triazole derivatives: a series of Darapladib analogues as orally active Lp-PLA2 inhibitors.

Wei Zhang, Jianhua Shen, Yi-ping Wang, 2013, Bioorganic & medicinal chemistry letters.

Brownian dynamics simulations of interaction between scorpion toxin Lq2 and potassium ion channel.

J M Briggs, Xiaomin Luo, Kaixian Chen, 2001, Biophysical journal.

Discovery of Intestinal Targeted TGR5 Agonists for the Treatment of Type 2 Diabetes.

Jianhua Shen, Meng-meng Ning, Yang-liang Ye, 2015, Journal of medicinal chemistry.

Inhibitory mode of indole-2-carboxamide derivatives against HLGPa: molecular docking and 3D-QSAR analyses.

Hong Liu, Xu Shen, Hualiang Jiang, 2004, Bioorganic & medicinal chemistry.

Agonist–PPARγ interactions: Molecular modeling study with docking approach

Jianhua Shen, Xiaoying Xu, Xiao-min Luo, 2003 .

Conserved class B GPCR activation by a biased intracellular agonist

Jianhua Shen, Xinheng He, Junrui Li, 2023, Nature.