F. Gil-Ortiz

发表

The crystal structure of Pyrococcus furiosus UMP kinase provides insight into catalysis and regulation in microbial pyrimidine nucleotide biosynthesis.

C. Marco-Marín, F. Gil-Ortiz, V. Rubio, 2005, Journal of molecular biology.

Structure of acetylglutamate kinase, a key enzyme for arginine biosynthesis and a prototype for the amino acid kinase enzyme family, during catalysis.

F. Gil-Ortiz, V. Rubio, A. Marina, 2002, Structure.

Structural remodeling and oligomerization of human cathelicidin on membranes suggest fibril-like structures as active species

F. Gil-Ortiz, P. François, H. Lilie, 2017, Scientific Reports.

Structural and biochemical characterization of the relaxosome auxiliary proteins encoded on the Bacillus subtilis plasmid pLS20

F. Gil-Ortiz, M. Malfois, W. Meijer, 2022, Computational and structural biotechnology journal.

Improved cross-linked enzyme aggregates for the production of desacetyl beta-lactam antibiotics intermediates.

F. Gil-Ortiz, V. Rubio, F. García-Carmona, 2010, Bioresource technology.

Characterization and mutational analysis of a nicotinamide mononucleotide deamidase from Agrobacterium tumefaciens showing high thermal stability and catalytic efficiency

F. Gil-Ortiz, M. Pérez-Gilabert, R. Zapata-Pérez, 2017, PloS one.

The crystallography stations at the Alba synchrotron

F. Gil-Ortiz, F. Fauth, J. Benach, 2015 .

An uncharacterized FMAG_01619 protein from Fusobacterium mortiferum ATCC 9817 demonstrates that some bacterial macrodomains can also act as poly-ADP-ribosylhydrolases

José F. Hidalgo, F. Gil-Ortiz, R. Zapata-Pérez, 2019, Scientific Reports.

Developments in optics and performance at BL13-XALOC, the macromolecular crystallography beamline at the Alba Synchrotron

Claude Ruget, Carles Colldelram, Josep Nicolás, 2014, Journal of synchrotron radiation.

The crystal structure of the cephalosporin deacetylating enzyme acetyl xylan esterase bound to paraoxon explains the low sensitivity of this serine hydrolase to organophosphate inactivation.

F. Gil-Ortiz, V. Rubio, F. García-Carmona, 2011, The Biochemical journal.

Crystal structures and functional studies clarify substrate selectivity and catalytic residues for the unique orphan enzyme N-acetyl-D-mannosamine dehydrogenase.

F. Gil-Ortiz, V. Rubio, F. García-Carmona, 2014, The Biochemical journal.

Two crystal structures of Escherichia coli N-acetyl-L-glutamate kinase demonstrate the cycling between open and closed conformations.

Ignacio Fita, F. Gil-Ortiz, V. Rubio, 2010, Journal of molecular biology.

Arginine Biosynthesis in Thermotoga maritima: Characterization of the Arginine-Sensitive N-Acetyl-l-Glutamate Kinase

F. Gil-Ortiz, V. Rubio, M. L. Fernández-Murga, 2004, Journal of bacteriology.

Uridine as a new scavenger for synchrotron-based structural biology techniques.

F. Gil-Ortiz, M. Malfois, J. Juanhuix, 2017, Journal of synchrotron radiation.

An uncharacterized FMAG_01619 protein from Fusobacterium mortiferum ATCC 9817 demonstrates that some bacterial macrodomains can also act as poly-ADP-ribosylhydrolases

José F. Hidalgo, F. Gil-Ortiz, R. Zapata-Pérez, 2019, Scientific Reports.

Structural and functional analysis of Oceanobacillus iheyensis macrodomain reveals a network of waters involved in substrate binding and catalysis

F. Gil-Ortiz, J. Juanhuix, R. Zapata-Pérez, 2017, Open Biology.

Insight on an Arginine Synthesis Metabolon from the Tetrameric Structure of Yeast Acetylglutamate Kinase

F. Gil-Ortiz, V. Rubio, M. Crabeel, 2012, PloS one.

Glutamate-5-kinase from Escherichia coli: gene cloning, overexpression, purification and crystallization of the recombinant enzyme and preliminary X-ray studies.

F. Gil-Ortiz, V. Rubio, I. Pérez-Arellano, 2004, Acta crystallographica. Section D, Biological crystallography.

Towards structural understanding of feedback control of arginine biosynthesis: cloning and expression of the gene for the arginine-inhibited N-acetyl-L-glutamate kinase from Pseudomonas aeruginosa, purification and crystallization of the recombinant enzyme and preliminary X-ray studies.

F. Gil-Ortiz, V. Rubio, M. L. Fernández-Murga, 2002, Acta crystallographica. Section D, Biological crystallography.

Structural bases of feed-back control of arginine biosynthesis, revealed by the structures of two hexameric N-acetylglutamate kinases, from Thermotoga maritima and Pseudomonas aeruginosa.

Alexei Vagin, Ignacio Fita, F. Gil-Ortiz, 2006, Journal of molecular biology.

A novel two-domain architecture within the amino acid kinase enzyme family revealed by the crystal structure of Escherichia coli glutamate 5-kinase.

Ignacio Fita, Javier Cervera, C. Marco-Marín, 2007, Journal of molecular biology.

New Insight into the Transcarbamylase Family: The Structure of Putrescine Transcarbamylase, a Key Catalyst for Fermentative Utilization of Agmatine

F. Gil-Ortiz, V. Rubio, Á. Cantín, 2012, PloS one.

Substrate binding and catalysis in carbamate kinase ascertained by crystallographic and site-directed mutagenesis studies: movements and significance of a unique globular subdomain of this key enzyme for fermentative ATP production in bacteria.

Alberto Marina, Ignacio Fita, F. Gil-Ortiz, 2010, Journal of molecular biology.

The course of phosphorus in the reaction of N-acetyl-L-glutamate kinase, determined from the structures of crystalline complexes, including a complex with an AlF(4)(-) transition state mimic.

Ignacio Fita, F. Gil-Ortiz, V. Rubio, 2003, Journal of molecular biology.

Expanding the β-III Spectrin-Associated Phenotypes toward Non-Progressive Congenital Ataxias with Neurodegeneration

F. Gil-Ortiz, B. Pérez-Dueñas, C. Espinós, 2021, International journal of molecular sciences.

The crystal structure of the complex of PII and acetylglutamate kinase reveals how PII controls the storage of nitrogen as arginine

Asunción Contreras, Ignacio Fita, C. Marco-Marín, 2007, Proceedings of the National Academy of Sciences.

Structural remodeling and oligomerization of human cathelicidin on membranes suggest fibril-like structures as active species

F. Gil-Ortiz, P. François, H. Lilie, 2017, Scientific Reports.

A New Paradigm in the Relationship between Gut Microbiota and Breast Cancer: β-glucuronidase Enzyme Identified as Potential Therapeutic Target

F. Gil-Ortiz, A. Llombart-Cussac, M. Fernández-Murga, 2023, Pathogens.

First Functional and Mutational Analysis of Group 3 N-Acetylneuraminate Lyases from Lactobacillus antri and Lactobacillus sakei 23K

F. Gil-Ortiz, F. García-Carmona, Á. Sánchez-Ferrer, 2014, PloS one.

Two crystal structures of Escherichia coli N-acetyl-L-glutamate kinase demonstrate the cycling between open and closed conformations.

F. Gil-Ortiz, V. Rubio, M. L. Fernández-Murga, 2010, Journal of molecular biology.