H. Desaire

发表

Two New Tools for Glycopeptide Analysis Researchers: A Glycopeptide Decoy Generator and a Large Data Set of Assigned CID Spectra of Glycopeptides.

Xiaomeng Su, David Hua, Zhikai Zhu, 2017, Journal of proteome research.

Comparative Analysis of the Glycosylation Profiles of Membrane-Anchored HIV-1 Envelope Glycoprotein Trimers and Soluble gp140

David Hua, E. Go, H. Desaire, 2015, Journal of Virology.

Glycopeptide analysis by mass spectrometry.

H. Desaire, Dilusha S Dalpathado, Dilusha S. Dalpathado, 2008, The Analyst.

Glycoprotein profiling by electrospray mass spectrometry

H. Desaire, Hui Jiang, Vladimir Y. Butnev, 2004, Journal of the American Society for Mass Spectrometry.

GlycoPep MassList: software to generate massive inclusion lists for glycopeptide analyses

Xiaomeng Su, Zhikai Zhu, E. Go, 2016, Analytical and Bioanalytical Chemistry.

Glycosylation site-specific analysis of clade C HIV-1 envelope proteins.

E. Go, H. Desaire, H. Liao, 2009, Journal of proteome research.

Dissecting the Dissociation Patterns of Fucosylated Glycopeptides Undergoing CID: A Case Study in Improving Automated Glycopeptide Analysis Scoring Algorithms.

Xiaomeng Su, David Hua, Heather Desaire, 2018, Analytical methods : advancing methods and applications.

Glycopeptide Analysis, Recent Developments and Applications*

H. Desaire, 2013, Molecular & Cellular Proteomics.

GlycoPep DB: a tool for glycopeptide analysis using a "Smart Search".

E. Go, H. Desaire, Dilusha S Dalpathado, 2007, Analytical chemistry.

Simplification of mass spectral analysis of acidic glycopeptides using GlycoPep ID.

E. Go, H. Desaire, Dilusha S Dalpathado, 2007, Analytical chemistry.

GlycoPep grader: a web-based utility for assigning the composition of N-linked glycopeptides.

David Hua, E. Go, H. Desaire, 2012, Analytical chemistry.

GlycoPep Detector: a tool for assigning mass spectrometry data of N-linked glycopeptides on the basis of their electron transfer dissociation spectra.

Zhikai Zhu, David Hua, E. Go, 2013, Analytical chemistry.

New Glycoproteomics Software, GlycoPep Evaluator, Generates Decoy Glycopeptides de Novo and Enables Accurate False Discovery Rate Analysis for Small Data Sets

Xiaomeng Su, Zhikai Zhu, E. Go, 2014, Analytical chemistry.

Targeted selection of HIV-specific antibody mutations by engineering B cell maturation

F. Alt, M. Borgnia, E. Go, 2019, Science.

Carbohydrates on Proteins: Site-Specific Glycosylation Analysis by Mass Spectrometry.

Zhikai Zhu, Heather Desaire, Zhikai Zhu, 2015, Annual review of analytical chemistry.

Structural insights into the conformational plasticity of the full-length trimeric HIV-1 envelope glycoprotein precursor

E. Go, H. Desaire, Shijian Zhang, 2018, bioRxiv.

Stabilizing Exposure of Conserved Epitopes by Structure Guided Insertion of Disulfide Bond in HIV-1 Envelope Glycoprotein

E. Go, H. Desaire, D. Montefiori, 2013, PloS one.

Envelope Deglycosylation Enhances Antigenicity of HIV-1 gp41 Epitopes for Both Broad Neutralizing Antibodies and Their Unmutated Ancestor Antibodies

T. Kepler, A. Trkola, E. Go, 2011, PLoS pathogens.

HAMS: High-Affinity Mass Spectrometry Screening. A High-Throughput Screening Method for Identifying the Tightest-Binding Lead Compounds for Target Proteins with No False Positive Identifications

Zhikai Zhu, E. Go, H. Desaire, 2016, Journal of The American Society for Mass Spectrometry.

Software for automated interpretation of mass spectrometry data from glycans and glycopeptides.

Heather Desaire, Carrie L Woodin, Morgan Maxon, 2013, The Analyst.

A strategy for the determination of enzyme kinetics using electrospray ionization with an ion trap mass spectrometer.

H. Desaire, J. Leary, M. Beyer, 2001, Analytical chemistry.

Utilization of MS3 spectra for the multicomponent quantification of diastereomeric N-acetylhexosamines

H. Desaire, J. Leary, 2000, Journal of the American Society for Mass Spectrometry.

Dataset of why inclusion matters for Alzheimer's disease biomarker discovery in plasma

H. Desaire, O. Lopez, Renã A. S. Robinson, 2021, Data in brief.

Evidence of block and randomly sequenced chondroitin polysaccharides: sequential enzymatic digestion and quantification using ion trap tandem mass spectrometry.

H. Desaire, J. Leary, T. Sirich, 2001, Analytical chemistry.

cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV‐1 envelope glycoprotein vaccine candidate

E. Go, H. Desaire, John P. Moore, 2017, Biotechnology and bioengineering.

Recent mass spectrometry-based techniques and considerations for disulfide bond characterization in proteins

J. Lakbub, H. Desaire, Joshua T Shipman, 2018, Analytical and Bioanalytical Chemistry.

Structural insight into the novel iron‐coordination and domain interactions of transferrin‐1 from a model insect, Manduca sexta

E. Go, H. Desaire, K. Battaile, 2020, Protein science : a publication of the Protein Society.

Clinically Viable Assay for Monitoring Uromodulin Glycosylation.

M. W. Patabandige, E. Go, H. Desaire, 2020, Journal of the American Society for Mass Spectrometry.

Glycan reader: Automated sugar identification and simulation preparation for carbohydrates and glycoproteins

Alexander D. MacKerell, Sunhwan Jo, Wonpil Im, 2011, J. Comput. Chem..

Identification of sulfation sites of metabolites and prediction of the compounds’ biological effects

H. Desaire, Lin Yi, J. Tunge, 2006, Analytical and bioanalytical chemistry.

Collision induced dissociation of alpha hydroxy acids: Evidence of an ion-neutral complex intermediate

H. Desaire, Mary L. Bandu, T. Grubbs, 2006 .

Advances, obstacles, and opportunities for machine learning in proteomics

E. Go, H. Desaire, David C. Hua, 2022, Cell Reports Physical Science.

Leveraging R (LevR) for fast processing of mass spectrometry data and machine learning: Applications analyzing fingerprints and glycopeptides

M. W. Patabandige, H. Desaire, Leah D. Pfeifer, 2022, Frontiers in Analytical Science.

Combined partial acid hydrolysis and electrospray ionization-mass spectrometry for the structural determination of oligosaccharides.

H. Desaire, J. Leary, S. Gaucher, 2000, Analytical chemistry.

Determinants of Tenascin-C and HIV-1 envelope binding and neutralization

E. Go, H. Desaire, H. Erickson, 2019, Mucosal Immunology.

Asymmetric structures and conformational plasticity of the uncleaved full-length human immunodeficiency virus (HIV-1) envelope glycoprotein trimer

E. Go, H. Desaire, Shijian Zhang, 2021, bioRxiv.

Emerging investigators special issue

D. E. Benson, H. Desaire, E. Hilder, 2006 .

Characterization of Glycosylation Proﬁles of HIV-1 Transmitted/Founder Envelopes by Mass Spectrometry (cid:1) †

E. Go, H. Desaire, Haiyan Chen, 2011 .

How (Not) to Generate a Highly Predictive Biomarker Panel Using Machine Learning.

H. Desaire, 2022, Journal of proteome research.

The effects of coordination number and ligand size on the gas phase dissociation and stereochemical differentiation of cobalt-coordinated monosaccharides

H. Desaire, J. Leary, 2001 .

Generation and Characterization of a Bivalent HIV-1 Subtype C gp120 Protein Boost for Proof-of-Concept HIV Vaccine Efficacy Trials in Southern Africa

E. Go, H. Desaire, H. Liao, 2016, PloS one.

Molecular orbital considerations in probing the stereoselective dissociations of cobalt-coordinated hexosamine monosaccharides

H. Desaire, J. Leary, M. Beyer, 2001, Journal of the American Society for Mass Spectrometry.

Alcohol Chain Length and Mole Fraction Dependence of the Stability of Tetrakis(cumylphenoxy)phthalocyanine and Alcohol Langmuir Films

Grace M. Credo, H. Desaire, S. Baker, 1998 .

Collision Induced Dissociation Products of Disulfide-Bonded Peptides: Ions Result from the Cleavage of More Than One Bond

E. Go, H. Desaire, Daniel F. Clark, 2011, Journal of the American Society for Mass Spectrometry.

Glycosylation and Disulfide Bond Analysis of Transiently and Stably Expressed Clade C HIV-1 gp140 Trimers in 293T Cells Identifies Disulfide Heterogeneity Present in Both Proteins and Differences in O-Linked Glycosylation

E. Go, H. Desaire, Eden P. Go, 2014, Journal of proteome research.

Detection and quantification of the sulfated disaccharides in chondroitin sulfate by electrospray tandem mass spectrometry

Heather Desaire, Julie A. Leary, H. Desaire, 2000, Journal of the American Society for Mass Spectrometry.

Chromatofocusing fails to separate hFSH isoforms on the basis of glycan structure.

H. Desaire, Vladimir Y. Butnev, G. Bousfield, 2008, Biochemistry.

Comparative glycomics of the glycoprotein follicle stimulating hormone: glycopeptide analysis of isolates from two mammalian species.

E. Go, H. Desaire, Vladimir Y. Butnev, 2006, Biochemistry.

When can glycopeptides be assigned based solely on high-resolution mass spectrometry data?

H. Desaire, David C. Hua, 2009 .

Rapid LC-MS Based High-Throughput Screening Method, Affording No False Positives or False Negatives, Identifies a New Inhibitor for Carbonic Anhydrase

J. Lakbub, E. Go, H. Desaire, 2017, Scientific Reports.

Prediction of MS/MS data. 1. A focus on pharmaceuticals containing carboxylic acids.

Heather Desaire, H. Desaire, Mary L. Bandu, 2004, Analytical chemistry.

Application of the statistical test of equivalent pathways (STEP) method to the triple quadrupole mass spectrometer.

H. Desaire, Mary L. Bandu, Qing Chang, 2007, Rapid communications in mass spectrometry : RCM.

The STEP method (statistical test of equivalent pathways): application to pharmaceuticals.

H. Desaire, Mary L. Bandu, 2006, The Analyst.

Characterization of host-cell line specific glycosylation profiles of early transmitted/founder HIV-1 gp120 envelope proteins.

E. Go, H. Desaire, H. Liao, 2013, Journal of proteome research.

Multicomponent quantification of diastereomeric hexosamine monosaccharides using ion trap tandem mass spectrometry.

H. Desaire, J. Leary, 1999, Analytical chemistry.

Differentiation of diastereomeric N-acetylhexosamine monosaccharides using ion trap tandem mass spectrometry.

H. Desaire, J. Leary, 1999, Analytical chemistry.

The Aristotle Classifier: Using the Whole Glycomic Profile To Indicate a Disease State.

David Hua, Heather Desaire, Eden P Go, 2019, Analytical chemistry.

Interlaboratory Study on Differential Analysis of Protein Glycosylation by Mass Spectrometry: The ABRF Glycoprotein Research Multi-Institutional Study 2012*

Haixu Tang, Daniel Kolarich, Wolfgang Jabs, 2013, Molecular & Cellular Proteomics.

Why Inclusion Matters for Alzheimer's Disease Biomarker Discovery in Plasma.

H. Desaire, O. Lopez, M. Kamboh, 2021, Journal of Alzheimer's disease : JAD.

Glycosylation site-specific analysis of HIV envelope proteins (JR-FL and CON-S) reveals major differences in glycosylation site occupancy, glycoform profiles, and antigenic epitopes' accessibility.

E. Go, H. Desaire, H. Liao, 2008, Journal of proteome research.

Simple approach to assign disulfide connectivity using extracted ion chromatograms of electron transfer dissociation spectra.

E. Go, H. Desaire, Daniel F. Clark, 2013, Analytical chemistry.

Disulfide Bond Characterization of Endogenous IgG3 Monoclonal Antibodies Using LC-MS: An Investigation of IgG3 Disulfide-mediated Isoforms.

Ishan S. Shah, J. Lakbub, Zhikai Zhu, 2016, Analytical methods : advancing methods and applications.

Post-translational Modifications of Recombinant Human Lysyl Oxidase-like 2 (rhLOXL2) Secreted from Drosophila S2 Cells*

E. Go, H. Desaire, Kathryn R. Rebecchi, 2013, The Journal of Biological Chemistry.

Characterization of Glycosylation Profiles of HIV-1 Transmitted/Founder Envelopes by Mass Spectrometry

E. Go, H. Desaire, Haiyan Chen, 2011, Journal of Virology.

Identifying lactone hydrolysis in pharmaceuticals. A tool for metabolite structural characterization.

H. Desaire, Mary L. Bandu, Lin Yi, 2005, Analytical chemistry.

Asymmetric Structures and Conformational Plasticity of the Uncleaved Full-Length Human Immunodeficiency Virus Envelope Glycoprotein Trimer

E. Go, H. Desaire, Shijian Zhang, 2021, Journal of virology.

Glycosylation Benchmark Profile for HIV-1 Envelope Glycoprotein Production Based on Eleven Env Trimers

E. Go, H. Desaire, Shijian Zhang, 2017, Journal of Virology.

Analysis of Glycosylation and Disulfide Bonding of Wild-Type SARS-CoV-2 Spike Glycoprotein

E. Go, H. Desaire, Shijian Zhang, 2021, Journal of virology.

Method for Quantifying Oxidized Methionines and Application to HIV-1 Env

E. Go, H. Desaire, Eden P. Go, 2018, Journal of The American Society for Mass Spectrometry.

Absolute Quantitation of Glycosylation Site Occupancy Using Isotopically Labeled Standards and LC-MS

Zhikai Zhu, E. Go, H. Desaire, 2014, Journal of The American Society for Mass Spectrometry.

Antigenicity and Immunogenicity of HIV-1 Envelope Trimers Complexed to a Small-Molecule Viral Entry Inhibitor

E. Go, H. Desaire, H. Ding, 2020, Journal of Virology.

Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization

E. Go, H. Desaire, John P. Moore, 2017, Cell reports.

Interdomain Stabilization Impairs CD4 Binding and Improves Immunogenicity of the HIV-1 Envelope Trimer.

E. Go, H. Desaire, J. Mascola, 2018, Cell host & microbe.

Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates.

T. Kepler, B. Korber, E. Go, 2017, Cell reports.

HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions.

Jerome H. Kim, P. Zhang, E. Go, 2020, JCI insight.

Improving the presentation of V 2-associated broadly neutralizing antibody epitopes on HIV-1 envelope trimers via stabilization of the V 2 loop

E. Go, H. Desaire, A. Ward, 2017 .

Analysis of Glycosylation and Disulfide Bonding of Wild-Type SARS-CoV-2 Spike Glycoprotein

E. Go, H. Desaire, Shijian Zhang, 2021, bioRxiv.

Exposing the Brain Proteomic Signatures of Alzheimer's Disease in Diverse Racial Groups: Leveraging Multiple Data Sets and Machine Learning.

H. Desaire, Renã A. S. Robinson, K. Stepler, 2022, Journal of proteome research.

Quantitative clinical glycomics strategies: A guide for selecting the best analysis approach.

M. W. Patabandige, H. Desaire, Leah D. Pfeifer, 2021, Mass spectrometry reviews.

A general protease digestion procedure for optimal protein sequence coverage and post-translational modifications analysis of recombinant glycoproteins: application to the characterization of human lysyl oxidase-like 2 glycosylation.

E. Go, H. Desaire, Kathryn R. Rebecchi, 2011, Analytical chemistry.

Determinants of Tenascin-C and HIV-1 envelope binding and neutralization

E. Go, H. Desaire, H. Erickson, 2019, Mucosal Immunology.

The Aristotle Classifier Provides Accurate Identifications of Highly Similar Bacteria Analyzed by MALDI-TOF MS.

H. Desaire, David C. Hua, 2019, Analytical chemistry.

Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers

E. Go, H. Desaire, John P. Moore, 2015, Journal of Virology.

Comparison of HPLC/ESI-FTICR MS versus MALDI-TOF/TOF MS for glycopeptide analysis of a highly glycosylated HIV envelope glycoprotein

E. Go, H. Desaire, H. Liao, 2008, Journal of the American Society for Mass Spectrometry.

Development of fully functional proteins with novel glycosylation via enzymatic glycan trimming.

E. Go, H. Desaire, Eden P. Go, 2009, Journal of pharmaceutical sciences.

Asymmetric conformations of cleaved HIV-1 envelope glycoprotein trimers in styrene-maleic acid lipid nanoparticles

E. Go, H. Desaire, Shijian Zhang, 2023, Communications biology.

Improved Discrimination of Disease States Using Proteomics Data with the Updated Aristotle Classifier.

H. Desaire, David C. Hua, 2021, Journal of proteome research.

Stabilization of the V2 loop improves the presentation of V2 loop–associated broadly neutralizing antibody epitopes on HIV-1 envelope trimers

E. Go, H. Desaire, John P. Moore, 2019, The Journal of Biological Chemistry.

Label-free quantitation: A new glycoproteomics approach

E. Go, H. Desaire, Kathryn R. Rebecchi, 2009, Journal of the American Society for Mass Spectrometry.

Analysis of the disulfide bond arrangement of the HIV-1 envelope protein CON-S gp140 ΔCFI shows variability in the V1 and V2 regions.

E. Go, H. Desaire, Ying Zhang, 2011, Journal of proteome research.

Reductive amination of carbohydrates using NaBH(OAc)3

H. Desaire, Hui Jiang, Marcus A Kater, 2005, Analytical and bioanalytical chemistry.

Distinguishing phosphorylation and sulfation in carbohydrates and glycoproteins using ion-pairing and mass spectrometry

E. Go, H. Desaire, Hui Jiang, 2006, Journal of the American Society for Mass Spectrometry.

Maximizing coverage of glycosylation heterogeneity in MALDI-MS analysis of glycoproteins with up to 27 glycosylation sites.

E. Go, H. Desaire, Ying Zhang, 2008, Analytical chemistry.

So You Discovered a Potential Glycan-Based Biomarker; Now What? We Developed a High-Throughput Method for Quantitative Clinical Glycan Biomarker Validation

Joshua T. Shipman, Hanna T. Nguyen, Heather Desaire, 2020, ACS omega.

Native Conformation and Canonical Disulfide Bond Formation Are Interlinked Properties of HIV-1 Env Glycoproteins

E. Go, H. Desaire, John P. Moore, 2015, Journal of Virology.

High Level Stable Expression of Recombinant HIV gp120 in Glutamine Synthetase Gene Deficient HEK293T Cells.

E. Go, H. Desaire, P. Sun, 2021, Protein expression and purification.

Methods development for Analysis of Partially Deglycosylated Proteins and Application to an HIV Envelope Protein Vaccine Candidate.

E. Go, H. Desaire, H. Liao, 2011, International journal of mass spectrometry.

In-solution digestion of glycoproteins for glycopeptide-based mass analysis.

E. Go, H. Desaire, Kathryn R. Rebecchi, 2013, Methods in molecular biology.

Method for characterizing sulfated glycoproteins in a glycosylation site-specific fashion, using ion pairing and tandem mass spectrometry.

E. Go, H. Desaire, Hui Jiang, 2006, Analytical chemistry.

DecoyDeveloper: An On-Demand, De Novo Decoy Glycopeptide Generator.

Xiaomeng Su, David Hua, Heather Desaire, 2019, Journal of proteome research.

Recombinant Human Lysyl Oxidase-like 2 Secreted from Human Embryonic Kidney Cells Displays Complex and Acidic Glycans at All Three N-Linked Glycosylation Sites.

E. Go, H. Desaire, M. Mure, 2018, Journal of Proteome Research.

The opportunity cost of automated glycopeptide analysis: case study profiling the SARS-CoV-2 S glycoprotein

E. Go, H. Desaire, Shijian Zhang, 2021, Analytical and Bioanalytical Chemistry.

The Local-Balanced Model for Improved Machine Learning Outcomes on Mass Spectrometry Data Sets and Other Instrumental Data

M. W. Patabandige, H. Desaire, David C. Hua, 2021, Analytical and Bioanalytical Chemistry.

Distinguishing academic science writing from humans or ChatGPT with over 99% accuracy using off-the-shelf machine learning tools

H. Desaire, David C. Hua, Aleesa E. Chua, 2023, Cell reports. Physical science.

ChatGPT or academic scientist? Distinguishing authorship with over 99% accuracy using off-the-shelf machine learning tools

H. Desaire, David C. Hua, Romana Jarosova, 2023, ArXiv.

Distinguishing academic science writing from humans or ChatGPT with over 99% accuracy using off-the-shelf machine learning tools

H. Desaire, David C. Hua, Aleesa E. Chua, 2023, Cell reports. Physical science.

Rapid LC-MS Based High-Throughput Screening Method, Affording No False Positives or False Negatives, Identifies a New Inhibitor for Carbonic Anhydrase

J. Lakbub, H. Desaire, Eden P. Go, 2017, Scientific Reports.

STEP (Statistical Test of Equivalent Pathways) analysis: a mass spectrometric method for carbohydrates and peptides.

H. Desaire, Mary L. Bandu, R. Vachet, 2005, Analytical Chemistry.

A novel mass spectrometric method to distinguish isobaric monosaccharides that are phosphorylated or sulfated using ion-pairing reagents

H. Desaire, Hui Jiang, Ying Zhang, 2005, Journal of the American Society for Mass Spectrometry.

Characterizing O-linked glycopeptides by electron transfer dissociation: fragmentation rules and applications in data analysis.

Xiaomeng Su, Zhikai Zhu, H. Desaire, 2013, Analytical chemistry.

Interlaboratory Study on Differential Analysis of Protein Glycosylation by Mass Spectrometry: The ABRF Glycoprotein Research Multi-Institutional Study 2012*

Carthene R. Bazemore-Walker, Paula J. Griffin, H. Desaire, 2013, Molecular & Cellular Proteomics.

Glycopeptide Analysis, Recent Developments and Applications*

H. Desaire, 2013, Molecular & Cellular Proteomics.

Glycosylation site-specific analysis of clade C HIV-1 envelope proteins.

H. Desaire, Q. Chang, Laura L. Sutherland, 2009, Journal of proteome research.

Disulfide Bond Characterization of Endogenous IgG3 Monoclonal Antibodies Using LC-MS: An Investigation of IgG3 Disulfide-mediated Isoforms.

Ishan S. Shah, J. Lakbub, Zhikai Zhu, 2016, Analytical methods : advancing methods and applications.

Accurately detecting AI text when ChatGPT is told to write like a chemist

H. Desaire, David C. Hua, Aleesa E Chua, 2023, Cell reports. Physical science.

Enhanced detection of sulfated glycosylation sites in glycoproteins

H. Desaire, Hui Jiang, J. Irungu, 2005, Journal of the American Society for Mass Spectrometry.

Skin Surface Sebum Analysis by ESI-MS

H. Desaire, Madeline Isom, 2024, Biomolecules.