D. Ginty

D. Ginty, D. L. Beckman, A. Gaither, 1987, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock.

M E Greenberg, J. Kornhauser, M. Greenberg, 1993, Science.

Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways.

M E Greenberg, M. Greenberg, D. Ginty, 1993, Science.

Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB

M. Greenberg, D. Ginty, A. Bonni, 1994, Cell.

Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras

M. Greenberg, D. Ginty, M. J. Weber, 1994, Neuron.

Trans-synaptic regulation of gene expression

M. Greenberg, D. Ginty, H. Bading, 1992, Current Opinion in Neurobiology.

A Late Phase of Cerebellar Long-Term Depression Requires Activation of CaMKIV and CREB

D. Linden, D. Ginty, Sohyun Ahn, 1999, Neuron.

Spatial considerations for stimulus-dependent transcription in neurons.

A. Riccio, D. Ginty, S. Ahn, 2000, Annual review of physiology.

Calcium regulation of gene expression.

M E Greenberg, M. Greenberg, D. Ginty, 1995, Advances in second messenger and phosphoprotein research.

Calcium activates serum response factor-dependent transcription by a Ras- and Elk-1-independent mechanism that involves a Ca2+/calmodulin-dependent kinase

M. Greenberg, D. Ginty, T. Chatila, 1995, Molecular and cellular biology.

A Dominant-Negative Inhibitor of CREB Reveals that It Is a General Mediator of Stimulus-Dependent Transcription of c-fos

D. Ginty, M. Olive, C. Vinson, 1998, Molecular and Cellular Biology.

Growth and survival signals controlling sympathetic nervous system development.

D. Ginty, N. Glebova, 2005, Annual review of neuroscience.

Mitochondrial Cyclic AMP Response Element-binding Protein (CREB) Mediates Mitochondrial Gene Expression and Neuronal Survival*

D. Ginty, R. Ferrante, B. Lonze, 2005, Journal of Biological Chemistry.

Retinoic acid stimulates the differentiation of PC12 cells that are deficient in cAMP-dependent protein kinase

D. Ginty, J. Wagner, R. Scheibe, 1991, The Journal of cell biology.

the facial nerve ofand cooperates with Sema 3 A to pattern distinct compartments Vascular endothelial growth factor controls neuronal migration Material

A. Kolodkin, D. Ginty, D. Shima, 2011 .

Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve.

A. Kolodkin, D. Ginty, D. Shima, 2004, Genes & development.

A nitric oxide signaling pathway controls CREB-mediated gene expression in neurons.

S. Snyder, A. Riccio, D. Ginty, 2006, Molecular cell.

An evolving NGF–Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates

S. R. Wickramasinghe, D. Ginty, M. Capecchi, 2010, Nature Neuroscience.

Dynamic regulation of neuronal NO synthase transcription by calcium influx through a CREB family transcription factor-dependent mechanism.

D. Ginty, T. Dawson, V. Dawson, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Serum Response Factor Mediates NGF-Dependent Target Innervation by Embryonic DRG Sensory Neurons

S. R. Wickramasinghe, D. Ginty, N. Ramanan, 2008, Neuron.

Peripheral Mechanosensory Neuron Dysfunction Underlies Tactile and Behavioral Deficits in Mouse Models of ASDs

Lauren L. Orefice, D. Ginty, Anda M. Chirila, 2016, Cell.

Effects of PS1 Deficiency on Membrane Protein Trafficking in Neurons

D. Borchelt, D. Price, P. Wong, 1998, Neuron.

The emergence of transcriptional identity in somatosensory neurons

Allon M. Klein, D. Ginty, N. Sharma, 2020, Nature.

Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins

D. Ginty, Alice E. Chen, C. Fan, 2005, Nature.

A Hierarchical NGF Signaling Cascade Controls Ret-Dependent and Ret-Independent Events during Development of Nonpeptidergic DRG Neurons

S. R. Wickramasinghe, D. Ginty, T. Dawson, 2007, Neuron.

Semaphorin 3F Is a Bifunctional Guidance Cue for Dopaminergic Axons and Controls Their Fasciculation, Channeling, Rostral Growth, and Intracortical Targeting

A. Kolodkin, D. Ginty, S. M. Kolk, 2009, The Journal of Neuroscience.

Secreted Semaphorins Control Spine Distribution and Morphogenesis in the Postnatal CNS

R. Huganir, R. Clem, A. Kolodkin, 2009, Nature.

Semaphorin 3E and Plexin-D1 Control Vascular Pattern Independently of Neuropilins

Thomas M. Jessell, Chenghua Gu, Jean Livet, 2005, Science.

Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development.

Bernd Fritzsch, Chenghua Gu, Alex L Kolodkin, 2003, Developmental cell.

Hypermethylated SUPERMAN Epigenetic Alleles in Arabidopsis

M. Ehlers, L. Iversen, K. Stöckel, 1997 .

Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis

D. Ginty, C. Clish, K. Bullock, 2017, Neuron.

Identification and Characterization of Novel Substrates of Trk Receptors in Developing Neurons

A. Riccio, D. Ginty, Y. Zhang, 1998, Neuron.

LIG Family Receptor Tyrosine Kinase-Associated Proteins Modulate Growth Factor Signals during Neural Development

D. Ginty, M. Bothwell, C. Hillaire, 2009, Neuron.

Apoptosis, Axonal Growth Defects, and Degeneration of Peripheral Neurons in Mice Lacking CREB

A. Riccio, D. Ginty, B. Lonze, 2002, Neuron.

The gentle touch receptors of mammalian skin

D. Ginty, Ling Bai, David D. Ginty, 2014, Science.

Differential neuronal localizations and dynamics of phosphorylated and unphosphorylated type 1 inositol 1,4,5-trisphosphate receptors

S. Snyder, D. Brat, D. Ginty, 2001, Neuroscience.

Serine 133-Phosphorylated CREB Induces Transcription via a Cooperative Mechanism That May Confer Specificity to Neurotrophin Signals

M. Greenberg, D. Ginty, H. Dudek, 1995, Molecular and Cellular Neuroscience.

The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons

Wenqin Luo, Lishi Li, Shiaoching Gong, 2011, Cell.

The mechanosensory neurons of touch and their mechanisms of activation

D. Ginty, Annie Handler, 2021, Nature Reviews Neuroscience.

The encoding of touch by somatotopically aligned dorsal column subdivisions

D. Ginty, J. Turecek, Brendan P. Lehnert, 2022, bioRxiv.

The brain‐derived neurotrophic factor receptor TrkB is critical for the acquisition but not expression of conditioned incentive value

Alexander W. Johnson, X. Chen, P. Holland, 2008, The European journal of neuroscience.

The cellular and molecular basis of somatosensory neuron development

D. Ginty, N. Sharma, C. Santiago, 2021, Neuron.

Multivesicular bodies mediate long-range retrograde NGF-TrkA signaling

D. Ginty, Mengchen Ye, Kathryn M Lehigh, 2018, eLife.

Extrinsic and intrinsic signals converge on the Runx1/CBFβ transcription factor for nonpeptidergic nociceptor maturation

E. Turner, D. Ginty, K. O’Donovan, 2015, eLife.

Molecular Identification of Rapidly Adapting Mechanoreceptors and Their Developmental Dependence on Ret Signaling

D. Ginty, J. Milbrandt, F. Rice, 2009, Neuron.

A Chemical-Genetic Approach to Studying Neurotrophin Signaling

Xi Chen, Kevan M. Shokat, Katherine W. Scangos, 2005, Neuron.

Targeting Peripheral Somatosensory Neurons to Improve Tactile-Related Phenotypes in ASD Models

Maria K. Lehtinen, Lauren L. Orefice, G. Feng, 2019, Cell.

Long-Distance Control of Synapse Assembly by Target-Derived NGF

Anthony W. Harrington, D. Ginty, C. Deppmann, 2010, Neuron.

SH2-B and APS Are Multimeric Adapters That Augment TrkA Signaling

D. Ginty, Xiaozhong Qian, 2001, Molecular and Cellular Biology.

Neuropilin Is a Semaphorin III Receptor

Alex L Kolodkin, A. Kolodkin, D. Ginty, 1997, Cell.

Dystroglycan Organizes Axon Guidance Cue Localization and Axonal Pathfinding

D. Ginty, D. Leahy, Le Ma, 2012, Neuron.

Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure

Randy Schekman, R. Schekman, Yanshu Wang, 2009, Nature Cell Biology.

SRF binding to SRE 6.9 in the Arc promoter is essential for LTD in cultured Purkinje cells

R. Huganir, D. Linden, P. Worley, 2010, Nature Neuroscience.

DRG afferents that mediate physiologic and pathologic mechanosensation from the distal colon

D. Ginty, Ofer Mazor, N. Sharma, 2022, Cell.

Cortical Responses to Touch Reflect Subcortical Integration of LTMR Signals

C. Harvey, S. Panzeri, D. Ginty, 2021, Nature.

Parallel ascending spinal pathways for affective touch and pain

Shiaoching Gong, N. Heintz, D. Ginty, 2020, Nature.

Meissner corpuscles and their spatially intermingled afferents underlie gentle touch perception

Nicole L. Neubarth, Lauren L. Orefice, C. Harvey, 2020, Science.

Sexually Dimorphic BDNF Signaling Directs Sensory Innervation of the Mammary Gland

D. Ginty, L. Tessarollo, M. Rutlin, 2012, Science.

Linx Mediates Interaxonal Interactions and Formation of the Internal Capsule

D. Ginty, Dorothy V. Reimert, K. Mandai, 2014, Neuron.

Differential Requirements for Semaphorin 3F and Slit-1 in Axonal Targeting, Fasciculation, and Segregation of Olfactory Sensory Neuron Projections

A. Kolodkin, D. Ginty, J. Cloutier, 2004, The Journal of Neuroscience.

Neuropilin-2 Mediates Axonal Fasciculation, Zonal Segregation, but Not Axonal Convergence, of Primary Accessory Olfactory Neurons

A. Kolodkin, D. Ginty, J. Cloutier, 2002, Neuron.

The structure and organization of lanceolate mechanosensory complexes at mouse hair follicles

D. Ginty, Lishi Li, 2014, eLife.

Secreted Semaphorins Modulate Synaptic Transmission in the Adult Hippocampus

R. Huganir, A. Kolodkin, D. Ginty, 2005, The Journal of Neuroscience.

A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity

M. Greenberg, J. Blenis, D. Ginty, 1993, Molecular and cellular biology.

Spatially and Functionally Distinct Roles of the PI3-K Effector Pathway during NGF Signaling in Sympathetic Neurons

D. Ginty, R. Kuruvilla, Haihong Ye, 2000, Neuron.

Distinct Roles for Secreted Semaphorin Signaling in Spinal Motor Axon Guidance

Chenghua Gu, Artur Kania, Alex L Kolodkin, 2005, Neuron.

Calcium regulation of gene expression in neuronal cells.

M E Greenberg, M. Greenberg, A. Ghosh, 1994, Journal of neurobiology.

The activity of cAMP-dependent protein kinase is required at a posttranslational level for induction of voltage-dependent sodium channels by peptide growth factors in PC12 cells

D. Ginty, J. Wagner, G. Fanger, 1992, The Journal of cell biology.

Pincher-Mediated Macroendocytosis Underlies Retrograde Signaling by Neurotrophin Receptors

D. Ginty, S. Halegoua, R. Kuruvilla, 2005, The Journal of Neuroscience.

Evidence in Support of Signaling Endosome-Based Retrograde Survival of Sympathetic Neurons

D. Ginty, L. Zweifel, R. Kuruvilla, 2003, Neuron.

Characterization of an NGF–P-TrkA Retrograde-Signaling Complex and Age-Dependent Regulation of TrkA Phosphorylation in Sympathetic Neurons

D. Ginty, Brian A. Tsui-Pierchala, Brian A. Tsui-Pierchala, 1999, The Journal of Neuroscience.

An NGF-TrkA-mediated retrograde signal to transcription factor CREB in sympathetic neurons.

A. Riccio, D. Ginty, A Riccio, 1997, Science.

Neuropilin-2/PlexinA3 Receptors Associate with GluA1 and Mediate Sema3F-Dependent Homeostatic Scaling in Cortical Neurons

R. Huganir, A. Kolodkin, D. Ginty, 2017, Neuron.

Heterogeneous Requirement of NGF for Sympathetic Target Innervation In Vivo

D. Ginty, N. Glebova, 2004, The Journal of Neuroscience.

L-type Voltage-sensitive Ca2+ Channel Activation Regulates c-fos Transcription at Multiple Levels (*)

M. Greenberg, D. Ginty, A. Bonni, 1995, The Journal of Biological Chemistry.

Drosophila Fezf functions as a transcriptional repressor to direct layer-specific synaptic connectivity in the fly visual system

M. Weirauch, D. Ginty, Matthew Y. Pecot, 2021, Proceedings of the National Academy of Sciences.

Nerve injury disrupts temporal processing in the spinal cord dorsal horn through alterations in PV+ interneurons

D. Ginty, Jan Drugowitsch, C. Woolf, 2023, bioRxiv.

Semaphorin 3F Is Critical for Development of Limbic System Circuitry and Is Required in Neurons for Selective CNS Axon Guidance Events

A. Kolodkin, D. Ginty, M. Molliver, 2003, The Journal of Neuroscience.

Neuropilin-2 Is Required In Vivo for Selective Axon Guidance Responses to Secreted Semaphorins

S. Rastan, A. Kolodkin, D. Ginty, 2000, Neuron.

Patterning of cortical efferent projections by semaphorin-neuropilin interactions.

A. Ghosh, A. Kolodkin, D. Ginty, 1998, Science.

Palmitoylation regulates neuropilin-2 localization and function in cortical neurons and conveys specificity to semaphorin signaling via palmitoyl acyltransferases

A. Kolodkin, D. Ginty, R. Hand, 2022, bioRxiv.

Characterization of Neuropilin-1 Structural Features That Confer Binding to Semaphorin 3A and Vascular Endothelial Growth Factor 165*

Chenghua Gu, Alex L Kolodkin, A. Kolodkin, 2002, The Journal of Biological Chemistry.

Restricted inactivation of serum response factor to the cardiovascular system.

D. Ginty, K. L. de Mesy Bentley, J. Miano, 2004, Proceedings of the National Academy of Sciences of the United States of America.

A Neurotrophin Signaling Cascade Coordinates Sympathetic Neuron Development through Differential Control of TrkA Trafficking and Retrograde Signaling

D. Ginty, B. Lonze, L. Zweifel, 2004, Cell.

Steering Clear of Semaphorins: Neuropilins Sound the Retreat

A. Kolodkin, D. Ginty, 1997, Neuron.

Multiplexed peroxidase-based electron microscopy labeling enables simultaneous visualization of multiple cell types

W. Lee, D. Ginty, D. Paul, 2019, Nature Neuroscience.

Calcium Regulation of Gene Expression: Isn't That Spatial?

D. Ginty, D D Ginty, 1997, Neuron.

Retrogradely Transported TrkA Endosomes Signal Locally within Dendrites to Maintain Sympathetic Neuron Synapses.

D. Ginty, Kathryn M Lehigh, K. M. West, 2017, Cell reports.

Defining a Spinal Microcircuit that Gates Myelinated Afferent Input: Implications for Tactile Allodynia

Emily D. Kuehn, Masahiko Watanabe, D. Ginty, 2019, Cell reports.

Defining a Spinal Microcir cuit that Gates Myelinated Afferent Input : Implications for Tactile Allodynia Graphical Abstract Highlights

Emily D. Kuehn, D. Ginty, V. Abraira, 2019 .

Light entrainment and activation of signal transduction pathways in the SCN.

J. Kornhauser, M. Greenberg, D. Ginty, 1996, Progress in brain research.

Multiplexed peroxidase-based electron microscopy labeling enables simultaneous visualization of multiple cell types

W. Lee, D. Ginty, D. Paul, 2019, Nature Neuroscience.

Calretinin-expressing islet cells: a source of pre- and post-synaptic inhibition of non-peptidergic nociceptor input to the mouse spinal cord

Andrew M. Bell, Masahiko Watanabe, D. Ginty, 2023, bioRxiv.

A DRG genetic toolkit reveals molecular, morphological, and functional diversity of somatosensory neuron subtypes

D. Ginty, V. Kuchroo, N. Sharma, 2023, bioRxiv.

Induction of a Nerve Growth Factor‐Sensitive Kinase that Phosphorylates the DNA‐Binding Domain of the Orphan Nuclear Receptor NGFI‐B

M. Greenberg, D. Ginty, J. Milbrandt, 1995, Journal of neurochemistry.

Channeling , Rostral Growth , and Intracortical Targeting

A. Kolodkin, D. Ginty, S. M. Kolk, 2017 .

A Hypothalamic Circuit Underlying the Dynamic Control of Social Homeostasis

D. Ginty, N. Uchida, Mitsuko Watabe-Uchida, 2023, bioRxiv.

Calcium Signals Control Wnt-Dependent Dendrite Growth

X. Chen, D. Ginty, R. Alvania, 2006, Neuron.

Distinct Modes of Presynaptic Inhibition of Cutaneous Afferents and Their Functions in Behavior

D. Ginty, A. Tasnim, Qiyu Zhang, 2019, Neuron.

Krause corpuscles of the genitalia are vibrotactile sensors required for normal sexual behavior

D. Ginty, Annie Handler, Lijun Qi, 2023, bioRxiv.

The developmental timing of spinal touch processing alterations and its relation to ASD-associated behaviors in mouse models

Lauren L. Orefice, D. Ginty, R. Hakim, 2023, bioRxiv.

Three-dimensional reconstructions of mechanosensory end organs suggest a unifying mechanism underlying dynamic, light touch

W. Lee, D. Ginty, Annie Handler, 2023, bioRxiv.

Mechanoreceptor synapses in the brainstem shape the central representation of touch

C. Harvey, D. Ginty, Ling Bai, 2021, Cell.

Time-Resolved Fast Mammalian Behavior Reveals the Complexity of Protective Pain Responses.

David P. Roberson, D. Ginty, C. Alexandre, 2017, Cell reports.

Time-Resolved Fast Mamm alian Behavior Reveals the Complexity of Protective Pain Responses Graphical

David P. Roberson, D. Ginty, C. Alexandre, 2017 .

Unified Nomenclature for the Semaphorins/Collapsins

M. Poo, C. Shatz, C. Goodman, 1999, Cell.

Calretinin-expressing islet cells are a source of pre- and post-synaptic inhibition of non-peptidergic nociceptor input to the mouse spinal cord

Andrew M. Bell, Masahiko Watanabe, D. Ginty, 2023, Scientific reports.

Skin-type-dependent development of murine mechanosensory neurons.

John N. Hutchinson, D. Ginty, J. Lehoczky, 2023, Developmental cell.

Retrograde Control of Neural Circuit Formation

D. Ginty, C. Deppmann, 2006, Cell.

The projection-specific signals that establish functionally segregated dopaminergic synapses

W. Lee, Jie Zhou, D. Ginty, 2023, Cell.

The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn

Lauren L. Orefice, Emily D. Kuehn, S. Nelson, 2017, Cell.

Activity-dependent development of the body’s touch receptors

D. Ginty, Annie Handler, J. Turecek, 2023, bioRxiv.

Molecular Identification of Rapidly Adapting Mechanoreceptors and Their Developmental Dependence on Ret Signaling

D. Ginty, J. Milbrandt, F. Rice, 2009, Neuron.

Hypermethylated SUPERMAN Epigenetic Alleles in Arabidopsis

D. Ginty, S. Jacobsen, E. Meyerowitz, 1997 .

A model for neuronal competition during development

Ernst Niebur, Stefan Mihalas, Stefan Mihalas, 2008, International Journal of Developmental Neuroscience.

Coding of self and environment by Pacinian neurons in freely moving animals

D. Ginty, J. Turecek, 2023, Neuron.

Three-dimensional reconstructions of mechanosensory end organs suggest a unifying mechanism underlying dynamic, light touch

D. Ginty, Annie Handler, Wangchu Xiang, 2023, Neuron.

Nerve injury disrupts temporal processing in the spinal cord dorsal horn through alterations in PV+ interneurons

D. Ginty, Anda M. Chirila, A. Emanuel, 2024, Cell reports.

Krause corpuscles are genital vibrotactile sensors for sexual behaviours

D. Ginty, S. Liberles, Annie Handler, 2024, Nature.

A mouse DRG genetic toolkit reveals morphological and physiological diversity of somatosensory neuron subtypes

D. Ginty, V. Kuchroo, N. Sharma, 2024, Cell.

C-LTMRs mediate wet dog shakes via the spinoparabrachial pathway

D. Ginty, J. Turecek, Dawei Zhang, 2024, bioRxiv.

Supplemental Information Peripheral Mechanosensory Neuron Dysfunction Underlies Tactile and Behavioral De fi cits in Mouse Models of ASDs

D. Ginty, Anda M. Chirila, Joshua P. Head, 2016 .

What a privilege to reside at the synapse: NMDA receptor signaling to CREB

A. Riccio, D. Ginty, 2002, Nature Neuroscience.

The developmental timing of spinal touch processing alterations predicts behavioral changes in genetic mouse models of autism spectrum disorders

Lauren L. Orefice, D. Ginty, R. Hakim, 2024, Nature neuroscience.