A. Griffiths

发表

Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease

Sinead B. O'Leary, M. Daly, E. Lander, 2001, Nature Genetics.

A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene

Judy H. Cho, M. Daly, Annette Lee, 2006, Science.

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Judy H. Cho, P. Deloukas, J. Marchini, 2008, Nature Genetics.

IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes

David C. Wilson, Judy H. Cho, C. Gieger, 2018, Nature Communications.

FUT2 genotype and secretory status are not associated with fecal microbial composition and inferred function in healthy subjects

A. Paterson, P. Moayyedi, M. Silverberg, 2018, Gut microbes.

The treatment-naive microbiome in new-onset Crohn's disease.

Se Jin Song, M. Yassour, C. Huttenhower, 2014, Cell host & microbe.

Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature.

Timothy L. Tickle, C. Huttenhower, D. Gevers, 2014, The Journal of clinical investigation.

Inflammation, Antibiotics, and Diet as Environmental Stressors of the Gut Microbiome in Pediatric Crohn's Disease.

Eric Z. Chen, F. Bushman, A. Griffiths, 2015, Cell host & microbe.

Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease.

David C. Wilson, Joseph T. Glessner, J. Glessner, 2009, American journal of human genetics.

Induction and maintenance infliximab therapy for the treatment of moderate-to-severe Crohn's disease in children.

A. Griffiths, R. Baldassano, S. Kugathasan, 2007, Gastroenterology.

Retrospective Evaluation of the Safety and Effect of Adalimumab Therapy (RESEAT) in Pediatric Crohn’s Disease

A. Griffiths, S. Kugathasan, J. Rosh, 2009, The American Journal of Gastroenterology.

Long‐term outcome of maintenance infliximab therapy in children with Crohn's disease

A. Griffiths, N. LeLeiko, A. Bousvaros, 2009, Inflammatory bowel diseases.

Safety and efficacy of adalimumab for moderate to severe Crohn's disease in children.

A. Griffiths, R. Baldassano, M. Dubinsky, 2012, Gastroenterology.

Infliximab Maintains Durable Response and Facilitates Catch-up Growth in Luminal Pediatric Crohn's Disease

A. Griffiths, T. Walters, P. Church, 2014, Inflammatory bowel diseases.

Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn's disease.

A. Griffiths, J. Hugot, G. Veres, 2014, Journal of Crohn's & colitis.

Canadian Association of Gastroenterology Clinical Practice Guideline for the Medical Management of Pediatric Luminal Crohn’s Disease

P. Moayyedi, A. Griffiths, F. Tse, 2018, Journal of the Canadian Association of Gastroenterology.

Variants in TRIM22 That Affect NOD2 Signaling Are Associated With Very-Early-Onset Inflammatory Bowel Disease.

Eric E Schadt, Yongzhong Zhao, Christoph Klein, 2016, Gastroenterology.

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

Tariq Ahmad, Albert Cohen, Judy H Cho, 2010, Nature Genetics.

Review and clinical perspectives for the use of infliximab in ulcerative colitis.

A. Griffiths, A. Bitton, G. Greenberg, 2008, Canadian journal of gastroenterology = Journal canadien de gastroenterologie.

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

Tariq Ahmad, Katherine I. Morley, Vibeke Andersen, 2011, Nature Genetics.

Pediatricians Overestimate Importance of Physical Symptoms Upon Children’s Health Concerns

A. Griffiths, Anne M Griffiths, H. Loonen, 2002, Medical care.

Common variants at five new loci associated with early-onset inflammatory bowel disease

Johan Van Limbergen, David C Wilson, David C. Wilson, 2009, Nature Genetics.

Efficacy of oral methotrexate in paediatric Crohn’s disease: a multicentre propensity score study

David C. Wilson, A. Griffiths, R. Baldassano, 2014, Gut.

Linear Growth Improves during Infliximab Therapy in Children with Chronically Active Severe Crohn's Disease

A. Griffiths, T. Walters, A. Gilman, 2007, Inflammatory bowel diseases.

Systematic review with meta‐analysis: magnetic resonance enterography signs for the detection of inflammation and intestinal damage in Crohn's disease

A. Griffiths, M. Amitai, B. Feldman, 2015, Alimentary pharmacology & therapeutics.

Corticosteroids for maintaining remission of Crohn's disease.

A. Griffiths, R. Modigliani, K. Ewe, 2000, The Cochrane database of systematic reviews.

Corticosteroids for maintenance of remission in Crohn's disease.

A. Griffiths, R. Modigliani, K. Ewe, 2003, The Cochrane database of systematic reviews.

Diagnostic Delay Is Associated with Complicated Disease and Growth Impairment in Paediatric Crohn's Disease.

A. Griffiths, E. Seidman, E. Benchimol, 2020, Journal of Crohn's & colitis.

Diagnostic delay in Canadian children with inflammatory bowel disease is more common in Crohn’s disease and associated with decreased height

A. Griffiths, T. Walters, N. Carman, 2017, Archives of Disease in Childhood.

Guidelines for the management of growth failure in childhood inflammatory bowel disease.

A. Griffiths, T. Walters, R. Heuschkel, 2008, Inflammatory bowel diseases.

C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) or both? A systematic evaluation in pediatric ulcerative colitis.

M. Silverberg, A. Griffiths, N. LeLeiko, 2011, Journal of Crohn's & colitis.

Consensus guidelines for managing acute severe ulcerative colitis in children : a joint statement from ECCO , ESPGHAN , and the Pediatric IBD Porto Group Running title : Guidelines for managing acute severe colitis in children

David C. Wilson, A. Griffiths, R. Baldassano, 2014 .

Consensus for Managing Acute Severe Ulcerative Colitis in Children: A Systematic Review and Joint Statement From ECCO, ESPGHAN, and the Porto IBD Working Group of ESPGHAN

David C. Wilson, A. Griffiths, R. Baldassano, 2011, The American Journal of Gastroenterology.

Extraintestinal Manifestations of Pediatric Inflammatory Bowel Disease and Their Relation to Disease Type and Severity

A. Griffiths, N. LeLeiko, A. Bousvaros, 2010, Journal of pediatric gastroenterology and nutrition.

Management of Pediatric Ulcerative Colitis: Joint ECCO and ESPGHAN Evidence-based Consensus Guidelines

David C. Wilson, A. Griffiths, J. Hugot, 2012, Journal of pediatric gastroenterology and nutrition.

Clinical Presentation and Five-Year Therapeutic Management of Very Early-Onset Inflammatory Bowel Disease in a Large North American Cohort.

A. Griffiths, S. Hutfless, N. LeLeiko, 2015, The Journal of pediatrics.

Treatment of Hospitalized Adult Patients With Severe Ulcerative Colitis: Toronto Consensus Statements

A. Griffiths, A. Bitton, R. Enns, 2012, The American Journal of Gastroenterology.

Enteric Protein Loss Measured by Fecal α1Antitrypsin Clearance in the Assessment of Crohn's Disease Activity: A Study of Children and Adolescents

A. Griffiths, S. Soldin, J. Hamilton, 1986, Journal of pediatric gastroenterology and nutrition.

Growth Impairment in Pediatric Inflammatory Bowel Disease

A. Griffiths, T. Walters, 2013 .

Mechanisms of growth impairment in pediatric Crohn's disease

A. Griffiths, T. Walters, 2009, Nature Reviews Gastroenterology &Hepatology.

Nutrition support for pediatric patients with inflammatory bowel disease: a clinical report of the North American Society for Pediatric Gastroenterology, Hepatology And Nutrition.

A. Griffiths, R. Baldassano, E. Seidman, 2004, Journal of pediatric gastroenterology and nutrition.

Trends in Epidemiology of Pediatric Inflammatory Bowel Disease in Canada: Distributed Network Analysis of Multiple Population-Based Provincial Health Administrative Databases

D. Tanyingoh, G. Kaplan, A. Griffiths, 2017, The American Journal of Gastroenterology.

Prevalence and Clinical Features of Inflammatory Bowel Diseases Associated with Monogenic Variants, Identified by Whole-exome Sequencing in 1000 Children at a Single Center.

Andrei L. Turinsky, Arun K. Ramani, A. Paterson, 2020, Gastroenterology.

Genetic variants and pathways implicated in a pediatric inflammatory bowel disease cohort

David T. Okou, M. Daly, D. Cutler, 2018, Genes & Immunity.

Use of C-reactive protein in children with newly diagnosed inflammatory bowel disease.

A. Griffiths, N. Barrowman, D. Mack, 2011, The Journal of pediatrics.

Quality of Life in Inflammatory Bowel Disease: A Cross-Cultural Comparison of English and Canadian Children

A. Griffiths, A. Thomas, Adrian G. Thomas, 2001, Journal of pediatric gastroenterology and nutrition.

Outcomes of pediatric inflammatory bowel disease: socioeconomic status disparity in a universal-access healthcare system.

T. To, A. Griffiths, L. Rabeneck, 2011, The Journal of pediatrics.

Multimodal intervention to improve the transition of patients with inflammatory bowel disease from pediatric to adult care: protocol for a randomized controlled trial

A. Griffiths, E. Benchimol, T. Walters, 2022, BMC Gastroenterology.

Assessing disease activity using the pediatric Crohn’s disease activity index: Can we use subjective or objective parameters alone?

A. Griffiths, A. Otley, A. Grant, 2021, World journal of gastroenterology.

Consensus statements on the risk, prevention, and treatment of venous thromboembolism in inflammatory bowel disease: Canadian Association of Gastroenterology.

A. Griffiths, A. Bitton, C. Bernstein, 2014, Gastroenterology.

Engaging Patients and Caregivers in Research for Pediatric IBD: Top 10 Research Priorities.

A. Laupacis, A. Griffiths, Kate Murray, 2019, Journal of pediatric gastroenterology and nutrition.

Guideline for the Medical Management of Pediatric Luminal Crohn ’ s Disease

P. Moayyedi, A. Griffiths, F. Tse, 2019 .

Canadian Association of Gastroenterology Clinical Practice Guideline for the Medical Management of Pediatric Luminal Crohn's Disease.

P. Moayyedi, A. Griffiths, F. Tse, 2019, Gastroenterology.

Management of Paediatric Ulcerative Colitis, Part 2: Acute Severe Colitis—An Evidence-based Consensus Guideline From the European Crohn's and Colitis Organization and the European Society of Paediatric Gastroenterology, Hepatology and Nutrition

A. Griffiths, G. Veres, R. Russell, 2018, Journal of pediatric gastroenterology and nutrition.

Management of Paediatric Ulcerative Colitis, Part 2: Acute Severe Colitis; An Evidence-based Consensus Guideline from ECCO and ESPGHAN.

A. Griffiths, G. Veres, R. Russell, 2018, Journal of pediatric gastroenterology and nutrition.

Factors associated with early outcomes following standardized therapy in children with ulcerative colitis (PROTECT): a multicentre inception cohort study

A. Griffiths, R. Baldassano, M. Dubinsky, 2017, The lancet. Gastroenterology & hepatology.

Acute severe ulcerative colitis in children: A systematic review

A. Griffiths, D. Turner, 2011, Inflammatory bowel diseases.

Severe pediatric ulcerative colitis: a prospective multicenter study of outcomes and predictors of response.

M. Silverberg, A. Griffiths, N. LeLeiko, 2010, Gastroenterology.

Response to corticosteroids in severe ulcerative colitis: a systematic review of the literature and a meta-regression.

A. Griffiths, C. Walsh, A. Steinhart, 2007, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Severe paediatric ulcerative colitis: incidence, outcomes and optimal timing for second-line therapy

A. Griffiths, C. Walsh, K. Thomas, 2007, Gut.

Canadian Association of Gastroenterology Clinical Practice Guidelines: the use of infliximab in Crohn's disease.

H. Steinhart, A. Griffiths, A. Bitton, 2004, Canadian journal of gastroenterology = Journal canadien de gastroenterologie.

The Continental Divide: Anti-TNF Use in Pediatric IBD Is Different in North America Compared to Other Parts of the World

A. Griffiths, D. Turner, J. Hyams, 2018, Canadian journal of gastroenterology & hepatology.

Development of an index to define overall disease severity in IBD

S. Ng, C. O'Morain, M. Silverberg, 2016, Gut.

Ketotifen Therapy for Acute Ulcerative Colitis in Children (A Pilot Study)

A. Griffiths, P. Sherman, C. Roifman, 1998, Digestive Diseases and Sciences.

Intercenter variation in initial management of children with Crohn's disease

A. Griffiths, K. Kleinman, A. Bousvaros, 2007, Inflammatory bowel diseases.

Growth Improvement with Adalimumab Treatment in Children with Moderately to Severely Active Crohn's Disease

A. Griffiths, R. Baldassano, S. Eichner, 2017, Inflammatory bowel diseases.

A two-year longitudinal study of persistent lean tissue deficits in children with Crohn's disease.

A. Griffiths, F. Sylvester, J. Hyams, 2009, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Improvement in biomarkers of bone formation during infliximab therapy in pediatric Crohn's disease: results of the REACH study.

A. Griffiths, R. Baldassano, S. Kugathasan, 2008, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Management of Patients With Crohn’s Disease and Ulcerative Colitis During the Coronavirus Disease-2019 Pandemic: Results of an International Meeting

S. Ng, C. Lees, C. O'Morain, 2020, Gastroenterology.

Omega 3 fatty acids (fish oil) for maintenance of remission in ulcerative colitis.

A. Griffiths, D. Turner, A. Steinhart, 2007, The Cochrane database of systematic reviews.

Epidemiology of pediatric inflammatory bowel disease: A systematic review of international trends

A. Griffiths, E. Benchimol, P. Gozdyra, 2011, Inflammatory bowel diseases.

Hypothesis-free analysis of ATG16L1 demonstrates gene-wide extent of association with Crohn's disease susceptibility

M. Silverberg, A. Griffiths, D. Philpott, 2012, Gut.

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

Judy H Cho, Dan L Nicolae, Mark J Daly, 2007, Nature Genetics.

Clinical and Genomic Correlates of Neutrophil Reactive Oxygen Species Production in Pediatric Patients With Crohn's Disease.

David T. Okou, M. Daly, R. Xavier, 2018, Gastroenterology.

Assessment of reliability and validity of IBD phenotyping within the National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK) IBD Genetics Consortium (IBDGC)

Judy H. Cho, J. Rioux, M. Silverberg, 2007, Inflammatory bowel diseases.

Specificities of inflammatory bowel disease in childhood.

A. Griffiths, 2004, Best practice & research. Clinical gastroenterology.

Outcome Following Aminosalicylate Therapy in Children Newly Diagnosed As Having Ulcerative Colitis

A. Griffiths, N. LeLeiko, A. Bousvaros, 2013, Journal of pediatric gastroenterology and nutrition.

Erratum: Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 (Nature Genetics (2011) 43 (246-252))

Judy H. Cho, M. Daly, R. Ophoff, 2011 .

Serologic Reactivity Reflects Clinical Expression of Ulcerative Colitis in Children.

A. Griffiths, R. Baldassano, M. Dubinsky, 2018, Inflammatory bowel diseases.

Novel Anti-Glycan Antibodies Related to Inflammatory Bowel Disease Diagnosis and Phenotype

M. Silverberg, H. Steinhart, A. Griffiths, 2009, The American Journal of Gastroenterology.

Biological interventions for maintenance of mucosal healing in Crohn’s disease

A. Griffiths, M. Storr, P. Church, 2017, Cochrane Database of Systematic Reviews.

Biological interventions for induction of mucosal healing in Crohn’s disease

A. Griffiths, M. Storr, P. Church, 2017, Cochrane Database of Systematic Reviews.

Methotrexate for maintenance of remission in ulcerative colitis.

A. Griffiths, B. Vandermeer, J. Macdonald, 2015, The Cochrane database of systematic reviews.

Body Composition Using Air Displacement Plethysmography in Children With Inflammatory Bowel Disease.

A. Griffiths, M. Mouzaki, T. Walters, 2020, Journal of pediatric gastroenterology and nutrition.

Evaluation of the Pediatric Crohn Disease Activity Index: A Prospective Multicenter Experience

A. Griffiths, A. Katz, A. Bousvaros, 2005, Journal of pediatric gastroenterology and nutrition.

Toward enteral nutrition for the treatment of pediatric Crohn disease in Canada: a workshop to identify barriers and enablers.

Stanley N Cohen, A. Griffiths, T. Walters, 2015, Canadian journal of gastroenterology & hepatology.

Rural and Urban Residence During Early Life is Associated with Risk of Inflammatory Bowel Disease: A Population-Based Inception and Birth Cohort Study

F. Underwood, D. Tanyingoh, G. Kaplan, 2017, The American Journal of Gastroenterology.

Growth Abnormalities Persist in Newly Diagnosed Children With Crohn Disease Despite Current Treatment Paradigms

A. Griffiths, N. LeLeiko, A. Bousvaros, 2009, Journal of pediatric gastroenterology and nutrition.

Growth Retardation in Early-Onset Inflammatory Bowel Disease: Should We Monitor and Treat These Patients Differently?

A. Griffiths, 2009, Digestive Diseases.

Controlled Ileal Release Budesonide in Pediatric Crohn Disease: Efficacy and Effect on Growth

A. Griffiths, M. Zachos, J. L. Holmes, 2001, Journal of pediatric gastroenterology and nutrition.

Development of a quality-of-life index for pediatric inflammatory bowel disease: dealing with differences related to age and IBD type.

A. Griffiths, D. Nicholas, P. Sherman, 1999, Journal of pediatric gastroenterology and nutrition.

Fragmented fibronectin and other synovial fluid proteins in chronic arthritis: their relation to immune complexes.

A. Griffiths, D. Perrett, K. Herbert, 1989, Clinica chimica acta; international journal of clinical chemistry.

Benefit of oral immune globulin therapy in patients with immunodeficiency and chronic diarrhea.

A. Griffiths, C. Roifman, I. Melamed, 1991, The Journal of pediatrics.

Getting the NOD to Move Ahead

A. Griffiths, J. Critch, 2001, Pediatric Research.

Human ALPI deficiency causes inflammatory bowel disease and highlights a key mechanism of gut homeostasis

A. Griffiths, N. Warner, N. Kapel, 2018, EMBO molecular medicine.

Defects in Nicotinamide-adenine Dinucleotide Phosphate Oxidase Genes NOX1 and DUOX2 in Very Early Onset Inflammatory Bowel Disease

Judy H. Cho, M. Silverberg, A. Griffiths, 2015, Cellular and molecular gastroenterology and hepatology.

Pathological features of multiple endocrine neoplasia type IIb in childhood.

A. Griffiths, R. Byard, P. Thorner, 1990, Pediatric pathology.

Maintenance of remission in inflammatory bowel disease using omega‐3 fatty acids (fish oil): A systematic review and meta‐analyses

A. Griffiths, A. Steinhart, P. Shah, 2011, Inflammatory bowel diseases.

Omega 3 fatty acids (fish oil) for maintenance of remission in Crohn's disease.

A. Griffiths, P. Shah, D. Turner, 2009, The Cochrane database of systematic reviews.

Designing clinical trials in paediatric inflammatory bowel diseases: a PIBDnet commentary

A. Griffiths, R. Baldassano, M. Dubinsky, 2019, Gut.

Design Issues and Outcomes in Ibd Clinical Trials

H. Steinhart, A. Griffiths, S. Hanauer, 2005, Inflammatory bowel diseases.

Interleukin-6 is associated with steroid resistance and reflects disease activity in severe pediatric ulcerative colitis.

A. Griffiths, N. LeLeiko, A. Otley, 2013, Journal of Crohn's & colitis.

Levels of Peptidoleukotriene E4 Are Elevated in Active Crohn's Disease

A. Griffiths, A. Ford-hutchinson, P. Tagari, 1995, Journal of pediatric gastroenterology and nutrition.

Corrigendum: Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

Judy H. Cho, K. Roeder, M. Daly, 2009, Nature Genetics.

Management of Paediatric Ulcerative Colitis, Part 1: Ambulatory Care- an Evidence-Based Guideline from ECCO and ESPGHAN.

A. Griffiths, G. Veres, R. Russell, 2018, Journal of pediatric gastroenterology and nutrition.

Neutrophil dysfunction in glycogen storage disease Ib: association with Crohn's-like colitis.

A. Griffiths, J. Kapelushnik, R. Couper, 1991, Gastroenterology.

The Impact of Inflammatory Bowel Disease in Canada 2018: A Scientific Report from the Canadian Gastro-Intestinal Epidemiology Consortium to Crohn’s and Colitis Canada

G. Kaplan, A. Griffiths, A. Bitton, 2018, Journal of the Canadian Association of Gastroenterology.

Diagnostic and Therapeutic Approach in Paediatric Inflammatory Bowel Diseases: Results from a Clinical Practice Survey

A. Griffiths, O. Hradsky, J. Bronský, 2019, Journal of pediatric gastroenterology and nutrition.

Appraisal of the PIBD-classes criteria: a multicenter validation.

A. Griffiths, R. Russell, D. Turner, 2020, Journal of Crohn's & colitis.

Crohn’s and Colitis Canada’s 2021 Impact of COVID-19 and Inflammatory Bowel Disease in Canada: Executive Summary

G. Kaplan, A. Griffiths, A. Bitton, 2021, Journal of the Canadian Association of Gastroenterology.

Incidence of Inflammatory Bowel Disease in South Asian and Chinese People: A Population-Based Cohort Study from Ontario, Canada

A. Griffiths, B. Shah, E. Benchimol, 2021, Clinical epidemiology.

The phenotypic spectrum of new onset IBD in Canadian children of South Asian ethnicity: A prospective multi-centre comparative study.

A. Griffiths, E. Benchimol, T. Walters, 2021, Journal of Crohn's & colitis.

Predicting Outcomes in Pediatric Crohn's Disease for Management Optimization: Systematic Review and Consensus Statements from PIBD-Ahead Program.

A. Griffiths, M. Dubinsky, G. Veres, 2020, Gastroenterology.

Differentiation of Colonic Inflammatory Bowel Disease: Re-examination of Paediatric Inflammatory Bowel Disease Classes Algorithm With Resected Colon As the Criterion Standard.

A. Griffiths, T. Walters, I. Siddiqui, 2020, Journal of pediatric gastroenterology and nutrition.

Phenotypic variation in paediatric IBD by age: a multi-centre prospective inception cohort study of the Canadian Children IBD Network.

A. Griffiths, E. Seidman, E. Benchimol, 2019, Journal of Crohn's & colitis.

Biologics Delay Progression of Crohn’s Disease, but Not Early Surgery, in Children

A. Griffiths, J. Machan, N. LeLeiko, 2018, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Mucosal Expression of Type 2 and Type 17 Immune Response Genes Distinguishes Ulcerative Colitis From Colon-Only Crohn's Disease in Treatment-Naive Pediatric Patients.

A. Griffiths, R. Baldassano, N. LeLeiko, 2017, Gastroenterology.

Enteral nutritional therapy for induction of remission in Crohn's disease.

A. Griffiths, M. Tondeur, M. Zachos, 2007, The Cochrane database of systematic reviews.

Inflammatory Bowel Disease Characteristics Among African Americans, Hispanics, and Non-Hispanic Whites: Characterization of a Large North American Cohort

Judy H. Cho, J. Rioux, M. Silverberg, 2006, The American Journal of Gastroenterology.

Use of Placebo in Pediatric Inflammatory Bowel Diseases: A Position Paper From ESPGHAN, ECCO, PIBDnet, and the Canadian Children IBD Network

A. Griffiths, M. Dubinsky, S. Vermeire, 2016, Journal of pediatric gastroenterology and nutrition.

Traditional corticosteroids for induction of remission in Crohn's disease.

A. Griffiths, E. Benchimol, A. Steinhart, 2008, The Cochrane database of systematic reviews.

Rural and urban disparities in the care of Canadian patients with inflammatory bowel disease: a population-based study

F. Underwood, D. Tanyingoh, G. Kaplan, 2018, Clinical epidemiology.

Hospitalization With Clostridioides difficile in Pediatric Inflammatory Bowel Disease: a Population-Based Study

G. Kaplan, A. Griffiths, A. Bitton, 2022, Journal of pediatric gastroenterology and nutrition.

Nutrition in inflammatory bowel disease

A. Griffiths, S. Ling, S. Ling, 2000 .

Factors associated with early outcomes following standardized therapy in children with ulcerative colitis (PROTECT): a multicentre inception cohort study

Jessie, Lee, A. Griffiths, 2017, The lancet. Gastroenterology & hepatology.

Comparison of Multiple Breath Washout and Spirometry in Children with Primary Ciliary Dyskinesia and Cystic Fibrosis and Healthy Controls.

M. Rosenfeld, W. Wheeler, A. Griffiths, 2020, Annals of the American Thoracic Society.

Inflammatory Bowel Disease Increases the Risk of Venous Thromboembolism in Children: A Population-Based Matched Cohort Study

D. Tanyingoh, G. Kaplan, A. Griffiths, 2021, Journal of Crohn's & colitis.

STRIDE-II: An Update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining Therapeutic Goals for Treat-to-Target strategies in IBD.

A. Griffiths, W. Bemelman, D. Rubin, 2020, Gastroenterology.

Factors that determine risk for surgery in pediatric patients with Crohn's disease.

A. Griffiths, J. Machan, N. LeLeiko, 2010, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Budesonide for induction of remission in Crohn's disease.

A. Griffiths, E. Benchimol, A. Otley, 2008, The Cochrane database of systematic reviews.

Colonoscopic surveillance for cancer in ulcerative colitis: a critical review.

A. Griffiths, P. Sherman, 1997, Journal of pediatric gastroenterology and nutrition.

Analysis of Using the Total White Blood Cell Count to Define Severe New Onset Ulcerative Colitis in Children.

A. Griffiths, R. Baldassano, N. LeLeiko, 2020, Journal of pediatric gastroenterology and nutrition.

Enteral nutrition: the neglected primary therapy of active Crohn's disease.

A. Griffiths, 2000, Journal of pediatric gastroenterology and nutrition.

Magnetic Resonance Enterography indices for ileal Crohn's disease assessment: 1 Comparison between classical and machine-learning-based indices

A. Griffiths, M. Freiman, D. Turner, 2022 .

The Medical Management of Paediatric Crohn's Disease: an ECCO-ESPGHAN Guideline Update.

A. Griffiths, R. Russell, P. V. van Rheenen, 2020, Journal of Crohn's & colitis.

Oral tacrolimus treatment of severe colitis in children.

A. Griffiths, B. Kirschner, A. Bousvaros, 2000, The Journal of pediatrics.

Infliximab Is Not Associated With Increased Risk of Malignancy or Hemophagocytic Lymphohistiocytosis in Pediatric Patients With Inflammatory Bowel Disease.

A. Griffiths, R. Baldassano, M. Dubinsky, 2017, Gastroenterology.

Course and Treatment of Perianal Disease in Children Newly Diagnosed with Crohn's Disease

A. Griffiths, N. LeLeiko, A. Bousvaros, 2009, Inflammatory bowel diseases.

Clinical Features of Gastroduodenal Crohn's Disease in Adolescents

A. Griffiths, E. Alemayehu, P. Sherman, 1989, Journal of pediatric gastroenterology and nutrition.

Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci.

E S Lander, T S Brettin, K A Siminovitch, 2000, American journal of human genetics.

Genome-wide association study identifies five novel susceptibility loci for Crohn ' s disease and implicates a role for autophagy in disease pathogenesis

M. Daly, J. Rioux, R. Xavier, 2009 .

Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases

Constantin Polychronakos, Yiran Guo, Dong Li, 2016 .

Worldwide Management of Inflammatory Bowel Disease During the COVID-19 Pandemic: An International Survey

S. Ng, G. Kaplan, A. Griffiths, 2020, Inflammatory bowel diseases.

Gastral Antral Biopsy in the Differentiation of Pediatric Colitides

A. Griffiths, J. Critch, M. Stormon, 2003, American Journal of Gastroenterology.

Development of a multimodal machine-learning fusion model to non-invasively assess ileal Crohn's disease endoscopic activity

A. Griffiths, M. Freiman, D. Turner, 2022, Comput. Methods Programs Biomed..

M1146 The Ontario Crohn's & Colitis Cohort: Validation of An Algorithm to Identify Children Diagnosed with Inflammatory Bowel Disease Using Health Administrative Data

T. To, A. Griffiths, L. Rabeneck, 2009 .

Primary Sclerosing Cholangitis in Children With Inflammatory Bowel Diseases is Associated with Milder Clinical Activity but More Frequent Subclinical Inflammation and Growth Impairment.

M. Laeeq Khan, A. Griffiths, B. Kamath, 2020, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

The Impact of Inflammatory Bowel Disease in Canada 2018: Children and Adolescents with IBD

G. Kaplan, A. Griffiths, A. Bitton, 2018, Journal of the Canadian Association of Gastroenterology.

Allied Health Professional Support in Pediatric Inflammatory Bowel Disease: A Survey from the Canadian Children Inflammatory Bowel Disease Network—A Joint Partnership of CIHR and the CH.I.L.D. Foundation

A. Griffiths, E. Seidman, E. Benchimol, 2017, Canadian journal of gastroenterology & hepatology.

A. Griffiths, A. Bousvaros, S. Kugathasan, 2006, Inflammatory bowel diseases.

Budesonide Use in Pediatric Crohn Disease

A. Griffiths, N. LeLeiko, A. Bousvaros, 2012, Journal of pediatric gastroenterology and nutrition.

Changes to surgical and hospitalization rates of pediatric inflammatory bowel disease in Ontario, Canada (1994–2007)1,2

T. To, A. Griffiths, L. Rabeneck, 2011, Inflammatory bowel diseases.

Characterizing the Posttransfer Period Among Patients with Pediatric Onset IBD: The Impact of Academic Versus Community Adult Care on Emergent Health Resource Utilization.

A. Griffiths, A. Steinhart, A. Kovacs, 2017, Inflammatory bowel diseases.

Paediatric Inflammatory Bowel Disease: A Multi-Stakeholder Perspective to Improve Development of Drugs for Children and Adolescents

A. Griffiths, G. Vassal, D. Turner, 2022, Journal of Crohn's & colitis.

Medical Therapy for Pediatric Inflammatory Bowel Disease

A. Griffiths, M. Sherlock, 2012, Current Gastroenterology Reports.

Infant feeding practices and ulcerative colitis in childhood.

M. Corey, A. Griffiths, S. Koletzko, 1991, BMJ.

Role of infant feeding practices in development of Crohn's disease in childhood.

M. Corey, A. Griffiths, S. Koletzko, 1989, BMJ.

nduction and Maintenance Infliximab Therapy for the Treatment of oderate-to-Severe Crohn ’ s Disease in Children

A. Griffiths, S. Kugathasan, J. Markowitz, 2007 .

Supplementary enteral nutrition maintains remission in paediatric Crohn's disease.

M. Corey, A. Griffiths, P. Pencharz, 1996, Gut.

Higher Postinduction Infliximab Serum Trough Levels Are Associated With Healing of Fistulizing Perianal Crohn's Disease in Children.

A. Griffiths, E. Benchimol, T. Walters, 2018, Inflammatory bowel diseases.

Association of Early Postinduction Adalimumab Exposure With Subsequent Clinical and Biomarker Remission in Children with Crohn's Disease.

A. Griffiths, T. Walters, P. Church, 2020, Inflammatory bowel diseases.

Long-Term Outcomes With Adalimumab Therapy in Pediatric Crohn Disease: Associations With Adalimumab Exposure

A. Griffiths, T. Walters, P. Church, 2021, Journal of pediatric gastroenterology and nutrition.

Increased effectiveness of early therapy with anti-tumor necrosis factor-α vs an immunomodulator in children with Crohn's disease.

Stanley B. Cohen, A. Griffiths, R. Baldassano, 2014, Gastroenterology.

Hepatotoxicity Caused by Methotrexate Therapy in Children with Inflammatory Bowel Disease: A Systematic Review and Meta-analysis

A. Griffiths, J. Beyene, B. Feldman, 2014, Inflammatory bowel diseases.

Safety and efficacy of maintenance infliximab therapy for moderate-to-severe Crohn’s disease in children: REACH open-label extension

A. Griffiths, R. Baldassano, S. Kugathasan, 2011, Current medical research and opinion.

Utilization of Antitumor Necrosis Factor Biologics in Very Early Onset Inflammatory Bowel Disease: A Multicenter Retrospective Cohort Study From North America

Lina Karam, A. Griffiths, J. Kelsen, 2022, Journal of pediatric gastroenterology and nutrition.

Impact of Drug Approval Pathways for Paediatric Inflammatory Bowel Disease.

A. Griffiths, B. Feagan, V. Jairath, 2021, Journal of Crohn's & colitis.

Natural History of Very Early Onset Inflammatory Bowel Disease in North America: A Retrospective Cohort Study.

Lina Karam, A. Griffiths, J. Kelsen, 2020, Inflammatory bowel diseases.

Infliximab Therapy in Children With Concurrent Perianal Crohn Disease: Observations From REACH

Stanley N Cohen, A. Griffiths, R. Baldassano, 2009, Journal of pediatric gastroenterology and nutrition.

Perianal complications of pediatric Crohn's disease.

A. Griffiths, P. Sherman, B. Shandling, 1991, Journal of pediatric surgery.

Canadian Consensus Statements on the Transition of Adolescents and Young Adults with Inflammatory Bowel Disease from Pediatric to Adult Care: A Collaborative Initiative Between the Canadian IBD Transition Network and Crohn’s and Colitis Canada

A. Griffiths, S. Fowler, J. Marshall, 2022, Journal of the Canadian Association of Gastroenterology.

Characterizing the Posttransfer Period Among Patients with Pediatric Onset IBD: The Impact of Academic Versus Community Adult Care on Emergent Health Resource Utilization.

A. Griffiths, A. Steinhart, A. Kovacs, 2017, Inflammatory bowel diseases.

Methotrexate Following Unsuccessful Thiopurine Therapy in Pediatric Crohn's Disease

A. Griffiths, R. Baldassano, S. Kugathasan, 2007, The American Journal of Gastroenterology.

Fr493 DISEASE ACTIVITY IS ASSOCIATED WITH COVID-19 OUTCOMES IN IBD PATIENTS WITH EFFECT MODIFICATION BY AGE

G. Kaplan, A. Griffiths, C. Lamb, 2021, Gastroenterology.

Effects of Serum From Children with Newly Diagnosed Crohn Disease on Primary Cultures of Rat Osteoblasts

A. Griffiths, F. Sylvester, N. Wyzga, 2002, Journal of pediatric gastroenterology and nutrition.

Indirect and Out-of-Pocket Disease-associated Costs in Pediatric Inflammatory Bowel Disease: A Cross-sectional Analysis

A. Griffiths, C. Bernstein, J. Witt, 2022, Journal of pediatric gastroenterology and nutrition.

Medical therapy of paediatric inflammatory bowel disease

A. Griffiths, L. Scarallo, 2022, Nature Reviews Gastroenterology & Hepatology.

One‐year outcomes with ustekinumab therapy in infliximab‐refractory paediatric ulcerative colitis: a multicentre prospective study

A. Griffiths, T. Walters, H. Huynh, 2021, Alimentary pharmacology & therapeutics.

Predicting Outcomes in Pediatric Ulcerative Colitis for Management Optimization: Systematic Review and Consensus Statements from PIBD-Ahead Program.

A. Griffiths, M. Dubinsky, G. Veres, 2020, Gastroenterology.

Item Generation and Reduction Toward Developing a Patient-reported Outcome for Pediatric Ulcerative Colitis (TUMMY-UC)

A. Griffiths, A. Otley, D. Turner, 2017, Journal of pediatric gastroenterology and nutrition.

Endoscopic and clinical variables that predict sustained remission in children with ulcerative colitis treated with infliximab.

A. Griffiths, D. Turner, J. Hyams, 2013, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Fecal osteoprotegerin may guide the introduction of second‐line therapy in hospitalized children with ulcerative colitis

A. Griffiths, N. LeLeiko, D. Turner, 2011, Inflammatory bowel diseases.

Glucocorticoid bioactivity does not predict response to steroid therapy in severe pediatric ulcerative colitis

M. Silverberg, A. Griffiths, N. LeLeiko, 2010, Inflammatory bowel diseases.

Toxic Megacolon in Children With Inflammatory Bowel Disease: Clinical and Radiographic Characteristics

A. Griffiths, K. Thomas, E. Benchimol, 2008, The American Journal of Gastroenterology.

The natural history of corticosteroid therapy for ulcerative colitis in children.

A. Griffiths, N. LeLeiko, A. Bousvaros, 2006, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Anti-TNF therapies have eliminated the need for steroids in pediatric Crohn's disease: con. Why use a drug with an unknown long-term safety profile if more established therapies will be effective?

A. Griffiths, 2001, Inflammatory bowel diseases.

Thiopurine Monotherapy in Paediatric Inflammatory Bowel Disease: 20 Years After Markowitz.

A. Griffiths, D. Wilson, 2020, Journal of pediatric gastroenterology and nutrition.

Crohn’s and Colitis Canada’s 2021 Impact of COVID-19 and Inflammatory Bowel Disease in Canada: COVID-19 Vaccines—Biology, Current Evidence and Recommendations

G. Kaplan, A. Griffiths, A. Bitton, 2021, Journal of the Canadian Association of Gastroenterology.

Inflammatory Bowel Disease Clinical Activity is Associated with COVID-19 Severity Especially in Younger Patients

G. Kaplan, A. Griffiths, C. Lamb, 2021, Journal of Crohn's & colitis.

Sa1816 – Elevated Fecal Calprotectin in Healthy First Degree Relatives of Patients with Crohn's Disease is Associated with Future Diagnosis of Crohn's Disease

A. Paterson, P. Moayyedi, M. Silverberg, 2019, Gastroenterology.

Development and use of reporting guidelines for assessing the quality of validation studies of health administrative data.

Teresa To, Eric I Benchimol, Linda Rabeneck, 2011, Journal of clinical epidemiology.

Enteral nutritional therapy for inducing remission of Crohn's disease.

A. Griffiths, M. Tondeur, M. Zachos, 2001, The Cochrane database of systematic reviews.

The Effect of Early‐Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children

Ajay S. Gulati, A. Griffiths, R. Baldassano, 2018, The American Journal of Gastroenterology.

Increased Intestinal Permeability is Associated with Later Development of Crohn's Disease.

A. Paterson, M. Surette, C. Lees, 2020, Gastroenterology.

Pharmacokinetics of Infliximab in Children with Moderate-to-Severe Ulcerative Colitis: Results from a Randomized, Multicenter, Open-label, Phase 3 Study

A. Griffiths, J. Hyams, Honghui Zhou, 2013, Inflammatory bowel diseases.

Induction and maintenance therapy with infliximab for children with moderate to severe ulcerative colitis.

A. Griffiths, R. Baldassano, S. Kugathasan, 2012, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Oral budesonide for induction of remission in ulcerative colitis.

A. Griffiths, M. Sherlock, A. Steinhart, 2010, The Cochrane database of systematic reviews.

Methotrexate for maintenance of remission in ulcerative colitis.

A. Griffiths, B. Vandermeer, W. El-Matary, 2009, The Cochrane database of systematic reviews.

Acrodermatitis enteropathica with normal serum zinc levels: diagnostic value of small bowel biopsy and essential fatty acid determination.

A. Griffiths, B. Koletzko, D. Mack, 1989, Gut.

Serum Antibodies Associated with Complex Inflammatory Bowel Disease

M. Silverberg, A. Griffiths, A. Steinhart, 2013, Inflammatory bowel diseases.

Antibiotic Cocktail for Pediatric Acute Severe Colitis and the Microbiome: The PRASCO Randomized Controlled Trial.

H. Vlamakis, U. Gophna, A. Griffiths, 2019, Inflammatory bowel diseases.

Crohn ' s disease . Growth and clinical course of children with

J. H. MacMillan, A. Griffiths, P. Sherman, 2006 .

Inflammatory Bowel Disease: Working Group Report of the Second World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition

A. Griffiths, R. Baldassano, S. Murch, 2004, Journal of pediatric gastroenterology and nutrition.

Time for Personalized Biologic Therapy: One Size Does Not Fit All.

A. Griffiths, 2016, Journal of pediatric gastroenterology and nutrition.

Longitudinal lipid profiles on CAPD: their relationship to weight gain, comorbidity, and dialysis factors.

Sheryl M. Davies, A. Griffiths, S. Davies, 1998, Journal of the American Society of Nephrology : JASN.

A comparison of two methods of dietary assessment in peritoneal dialysis patients.

A. Griffiths, S. Davies, G. Russell, 1999, Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation.

Severe neutropenia following infliximab treatment in a child with ulcerative colitis.

A. Griffiths, M. Kirby-Allen, M. Sherlock, 2011, Inflammatory bowel diseases.

Magnetic resonance imaging to distinguish the type and severity of pediatric inflammatory bowel diseases.

B. Shuckett, A. Griffiths, P. Sherman, 2000, Journal of pediatric gastroenterology and nutrition.

Magnetic Resonance Enterography Cannot Replace Upper Endoscopy in Pediatric Crohn Disease: An Imagekids Sub-study

A. Griffiths, R. Baldassano, B. Weiss, 2017, Journal of pediatric gastroenterology and nutrition.

Collagenous colitis and eosinophilic gastritis in a 4‐year old girl: a case report and review of the literature

A. Griffiths, E. Benchimol, R. Kirsch, 2007, Acta paediatrica.

Association of host genome with intestinal microbial composition in a large healthy cohort

A. Paterson, P. Moayyedi, G. Kaplan, 2016, Nature Genetics.

Keeping an eye on Crohn's disease: orbital myositis as the presenting symptom.

A. Griffiths, J. R. Buncic, C. Durno, 1997, Canadian journal of gastroenterology = Journal canadien de gastroenterologie.

Development and validation of a pediatric Crohn's disease activity index.

J T Boyle, A. Griffiths, A. Katz, 1991, Journal of pediatric gastroenterology and nutrition.

Gut microbiome in primary sclerosing cholangitis: A review

A. Griffiths, B. Kamath, E. Wine, 2020, World journal of gastroenterology.

Faecal calprotectin, lactoferrin, M2-pyruvate kinase and S100A12 in severe ulcerative colitis: a prospective multicentre comparison of predicting outcomes and monitoring response

A. Griffiths, N. LeLeiko, T. Walters, 2010, Gut.

Dissecting Allele Architecture of Early Onset IBD Using High-Density Genotyping

David T. Okou, D. Cutler, A. Griffiths, 2015, PloS one.

Canadian Association of Gastroenterology Clinical Practice Guidelines: The use of tumour necrosis factor-alpha antagonist therapy in Crohn's disease.

A. Griffiths, A. Bitton, C. Bernstein, 2009, Canadian journal of gastroenterology = Journal canadien de gastroenterologie.

Characterization of Stool Virome in Children Newly Diagnosed With Moderate to Severe Ulcerative Colitis

A. Griffiths, R. Baldassano, N. LeLeiko, 2019, Inflammatory bowel diseases.

Polymorphisms in E-cadherin (CDH1) result in a mis-localised cytoplasmic protein that is associated with Crohn’s disease

M. Silverberg, A. Griffiths, D. Rotin, 2009, Gut.

New Onset Autoimmune Hepatitis during Anti‐Tumor Necrosis Factor‐Alpha Treatment in Children

A. Griffiths, B. Kamath, S. Ling, 2017, The Journal of pediatrics.

Fibronectin and immune complexes in rheumatic diseases.

A. Griffiths, D. Scott, J. Coppock, 1987, Annals of the rheumatic diseases.

Mucus sialylation determines intestinal host-commensal homeostasis

A. Griffiths, N. Warner, C. Bertozzi, 2022, Cell.

Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects.

Constantin Polychronakos, David C Wilson, Joseph T. Glessner, 2010, Human molecular genetics.

Ulcerative colitis loci on chromosomes 1 p 36 and 12 q 15 identified by genome-wide association study

Kathryn Roeder, Jean-Paul Achkar, M. Michael Barmada, 2009 .

A Machine Learning Approach to Identifying Causal Monogenic Variants in Inflammatory Bowel Disease

Arun K. Ramani, A. Griffiths, N. Warner, 2022, Gastro Hep Advances.

Stratification of Risk of Progression to Colectomy in Ulcerative Colitis using Measured and Predicted Gene Expression

Judy H. Cho, A. Kasarskis, A. Griffiths, 2021, bioRxiv.

Clinical Genomics for the Diagnosis of Monogenic Forms of Inflammatory Bowel Disease: A Position Paper From the Paediatric IBD Porto Group of European Society of Paediatric Gastroenterology, Hepatology and Nutrition

A. Griffiths, C. Klein, S. Travis, 2020, Journal of Pediatric Gastroenterology & Nutrition.

Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study

R. Xavier, M. Schirmer, A. Griffiths, 2019, The Lancet.

High density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

Hailiang Huang, Stephan Ripke, Andre Franke, 2014, Nature Genetics.

A Systematic Review of Monogenic Inflammatory Bowel Disease.

Judy H. Cho, A. Griffiths, C. Klein, 2021, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease

J. Danesh, M. Daly, J. Stelling, 2020, Nature Communications.

NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2

Judy H. Cho, C. Lees, J. Satsangi, 2011, Gut.

Pediatric modification of the Montreal classification for inflammatory bowel disease: The Paris classification

David C Wilson, Dan Turner, Thomas Walters, 2011, Inflammatory bowel diseases.

Single nucleotide polymorphisms that increase expression of the guanosine triphosphatase RAC1 are associated with ulcerative colitis.

Judy H. Cho, A. Paterson, C. Lees, 2011, Gastroenterology.

IL-10R Polymorphisms Are Associated with Very-early-onset Ulcerative Colitis

M. Silverberg, A. Griffiths, C. Klein, 2013, Inflammatory bowel diseases.

Clinical Genomics for the Diagnosis of Monogenic forms of Inflammatory Bowel Disease: A Position Paper from The Paediatric IBD Porto Group of ESPGHAN.

A. Griffiths, C. Klein, S. Travis, 2020, Journal of pediatric gastroenterology and nutrition.

Management of Paediatric Ulcerative Colitis, Part 1: Ambulatory Care—An Evidence-based Guideline From European Crohn's and Colitis Organization and European Society of Paediatric Gastroenterology, Hepatology and Nutrition

A. Griffiths, G. Veres, R. Russell, 2018, Journal of pediatric gastroenterology and nutrition.

Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study

Judy H. Cho, C. Huttenhower, R. Xavier, 2017, The Lancet.

Development, validation, and evaluation of a pediatric ulcerative colitis activity index: a prospective multicenter study.

A. Griffiths, A. Steinhart, D. Beaton, 2007, Gastroenterology.

The Crohn’s and Colitis Foundation of America

Athos Bousvaros, A. Griffiths, R. Baldassano, 2018, The Grants Register 2019.

Serum Protein Biomarkers of Fibrosis Aid in Risk Stratification of Future Stricturing Complications in Pediatric Crohn's Disease

Ajay S. Gulati, A. Griffiths, R. Baldassano, 2019, The American journal of gastroenterology.

Functional variants of OCTN cation transporter genes are associated with Crohn disease

Bill Newman, Christopher I Amos, Qiqing Huang, 2004, Nature Genetics.

Long ncRNA Landscape in the Ileum of Treatment-Naive Early-Onset Crohn Disease.

Ajay S. Gulati, A. Griffiths, R. Baldassano, 2018, Inflammatory bowel diseases.

Phenotypic and Genotypic Characteristics of Inflammatory Bowel Disease in French Canadians: Comparison With a Large North American Repository

Judy H. Cho, J. Rioux, M. Silverberg, 2009, The American Journal of Gastroenterology.

Blood-Derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation.

Judy H. Cho, David T. Okou, D. Cutler, 2019, Gastroenterology.

Inflammation, Antibiotics, and Diet as Environmental Stressors of the Gut Microbiome in Pediatric Crohn's Disease.

Eric Z. Chen, F. Bushman, A. Griffiths, 2017, Cell host & microbe.

Omega 3 fatty acids (fish oil) for maintenance of remission in Crohn's disease.

A. Griffiths, D. Turner, R. Lev-Tzion, 2014, The Cochrane database of systematic reviews.

Analysis of Genetic Association of Intestinal Permeability in Healthy First-degree Relatives of Patients with Crohn's Disease.

M. Surette, P. Moayyedi, G. Kaplan, 2019, Inflammatory bowel diseases.

Novel CARMIL2 loss-of-function variants are associated with pediatric inflammatory bowel disease

A. Griffiths, C. Klein, N. Warner, 2021, Scientific Reports.

Development and Validation of the Mucosal Inflammation Noninvasive Index For Pediatric Crohn's Disease.

A. Griffiths, R. Russell, T. Walters, 2019, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Which PCDAI Version Best Reflects Intestinal Inflammation in Pediatric Crohn Disease?

A. Griffiths, R. Baldassano, T. Walters, 2017, Journal of pediatric gastroenterology and nutrition.

Laboratory Values for Children With Newly Diagnosed Inflammatory Bowel Disease

A. Griffiths, N. LeLeiko, A. Bousvaros, 2007, Pediatrics.

Challenges and strategies of children and adolescents with inflammatory bowel disease: a qualitative examination

A. Griffiths, D. Nicholas, A. Otley, 2007, Health and quality of life outcomes.

Mucosal Inflammatory and Wound Healing Gene Programs Reveal Targets for Stricturing Behavior in Pediatric Crohn's Disease.

Ajay S. Gulati, A. Griffiths, G. Gibson, 2020, Journal of Crohn's & colitis.

A systematic prospective comparison of noninvasive disease activity indices in ulcerative colitis.

M. Silverberg, H. Steinhart, A. Griffiths, 2009, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Evolution of Pediatric Inflammatory Bowel Disease Unclassified (IBD-U): Incorporated With Serological and Gene Expression Profiles.

A. Griffiths, M. Dubinsky, N. LeLeiko, 2018, Inflammatory bowel diseases.

Outcome Following Infliximab Therapy in Children With Ulcerative Colitis

A. Griffiths, N. LeLeiko, A. Bousvaros, 2010, The American Journal of Gastroenterology.

Effect of early immunomodulator use in moderate to severe pediatric Crohn disease

A. Griffiths, N. LeLeiko, A. Bousvaros, 2008, Inflammatory bowel diseases.

Increasing incidence of paediatric inflammatory bowel disease in Ontario, Canada: evidence from health administrative data

T. To, A. Griffiths, L. Rabeneck, 2009, Gut.

Comparative Effectiveness of Nutritional and Biological Therapy in North American Children with Active Crohn's Disease

Frederic D Bushman, Amy Grant, Dale Lee, 2015, Inflammatory bowel diseases.

Retrospective Cohort Study of Methotrexate Use in the Treatment of Pediatric Crohn's Disease

A. Griffiths, N. LeLeiko, M. Kappelman, 2014, Inflammatory bowel diseases.

Mathematical weighting of the pediatric Crohn's disease activity index (PCDAI) and comparison with its other short versions

A. Griffiths, N. LeLeiko, T. Walters, 2012, Inflammatory bowel diseases.

S1189 Upper Gastrointestinal Involvement in Pediatric Crohn's Disease: Experience of a Large Multicenter Inception Cohort

A. Griffiths, N. LeLeiko, A. Bousvaros, 2010 .

Corticosteroid therapy in the age of infliximab: acute and 1-year outcomes in newly diagnosed children with Crohn's disease.

A. Griffiths, N. LeLeiko, A. Bousvaros, 2006, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Outcome after ileoanal anastomosis in pediatric patients with ulcerative colitis.

A. Griffiths, R. Superina, D. Wesson, 1998, Journal of pediatric gastroenterology and nutrition.

9 RELAPSE PREVENTION/GROWTH ENHANCEMENT IN PEDIATRIC CROHN'S DISEASE: MULTICENTER RANDOMIZED CONTROLLED TRIAL OF INTERMITTENT ENTERAL NUTRITION VERSUS ALTERNATE DAY PREDNISONE.

A. Griffiths, E. Seidman, R. Issenman, 1996 .

Meta-analysis of enteral nutrition as a primary treatment of active Crohn's disease.

A. Griffiths, P. Sherman, A. Ohlsson, 1995, Gastroenterology.

6 Crohn's disease in adolescents

A. Griffiths, D. Program, 1998 .

Hepatosplenic T‐cell lymphoma in adolescents and young adults with Crohn's disease: A cautionary tale?

A. Griffiths, J. Rosh, J. Hyams, 2007, Inflammatory bowel diseases.

Phenotype-Stratified Genetic Linkage Study Demonstrates that IBD2 Is an Extensive Ulcerative Colitis Locus

Judy H. Cho, J. Rioux, M. Silverberg, 2006, The American Journal of Gastroenterology.

Primary sclerosing cholangitis in 32 children: Clinical, laboratory, and radiographic features, with survival analysis

M. Corey, A. Griffiths, L. Blendis, 1995, Hepatology.

Transcriptional Risk Scores link GWAS to eQTL and Predict Complications in Crohn's Disease

Judy H. Cho, A. Griffiths, G. Gibson, 2017, Nature Genetics.

Genetic sharing and heritability of paediatric age of onset autoimmune diseases

Hongzhe Li, Constantin Polychronakos, Yiran Guo, 2015, Nature Communications.

Mutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease.

E. Schadt, A. Griffiths, C. Klein, 2014, Gastroenterology.

Oral budesonide for induction of remission in ulcerative colitis.

A. Griffiths, J. Macdonald, M. Sherlock, 2015, The Cochrane database of systematic reviews.

Budesonide for induction of remission in Crohn's disease.

G. Kaplan, A. Griffiths, E. Benchimol, 2015, The Cochrane database of systematic reviews.

Budesonide for Crohn's disease

A. Griffiths, E. Benchimol, A. Otley, 2009, Expert opinion on drug metabolism & toxicology.

Age-of-Diagnosis Dependent Ileal Immune Intensification and Reduced Alpha-Defensin in Older versus Younger Pediatric Crohn Disease Patients despite Already Established Dysbiosis

Ajay S. Gulati, C. Huttenhower, R. Xavier, 2018, Mucosal Immunology.

Early Change in Fecal Calprotectin Predicts One-Year Outcome in Children Newly Diagnosed With Ulcerative Colitis

A. Griffiths, A. Ananthakrishnan, N. LeLeiko, 2021, Journal of pediatric gastroenterology and nutrition.

Variants in nicotinamide adenine dinucleotide phosphate oxidase complex components determine susceptibility to very early onset inflammatory bowel disease.

M. Silverberg, A. Griffiths, S. Baksh, 2014, Gastroenterology.

Perianal Pediatric Crohn Disease Is Associated With a Distinct Phenotype and Greater Inflammatory Burden

A. Griffiths, M. Amitai, A. Towbin, 2018, Journal of pediatric gastroenterology and nutrition.

What's Hot in the Red Journal This Month?

A. Griffiths, R. Baldassano, M. Dubinsky, 2009, The American Journal of Gastroenterology.

Severe Ulcerative Colitis After Rituximab Therapy

A. Griffiths, T. Gonska, E. Harvey, 2010, Pediatrics.

IBD Genetic Risk Profile in Healthy First-Degree Relatives of Crohn's Disease Patients.

A. Paterson, M. Silverberg, A. Griffiths, 2016, Journal of Crohn's & colitis.

An SNP linkage scan identifies significant Crohn's disease loci on chromosomes 13q13.3 and, in Jewish families, on 1p35.2 and 3q29

J. Rioux, M. Silverberg, A. Cohen, 2008, Genes and Immunity.

Absence of linkage between inflammatory bowel disease and selected loci on chromosomes 3, 7, 12, and 16.

M. Daly, E. Lander, T. Hudson, 1998, Gastroenterology.

Mutation spectrum of NOD2 reveals recessive inheritance as a main driver of Early Onset Crohn’s Disease

A. Griffiths, N. Warner, O. Gottesman, 2021, Scientific Reports.

Mutation spectrum of NOD2 reveals recessive inheritance as a main driver of Early Onset Crohn’s Disease

A. Griffiths, N. Warner, O. Gottesman, 2017, Scientific Reports.

Anti TNF treatment of complex perianal fistulas in children without luminal Crohn's disease: Is it an option?

A. Griffiths, T. Walters, J. Langer, 2022, Journal of pediatric surgery.

Pico-Salax versus polyethylene glycol for bowel cleanout before colonoscopy in children: a randomized controlled trial.

A. Griffiths, E. Benchimol, S. Ling, 2009, Endoscopy.

Crohn’s and Colitis Canada’s 2021 Impact of COVID-19 and Inflammatory Bowel Disease in Canada: Children and Expectant Mothers With Inflammatory Bowel Disease

G. Kaplan, A. Griffiths, A. Bitton, 2021, Journal of the Canadian Association of Gastroenterology.

Determinants of Intestinal Permeability in Healthy First-Degree Relatives of Individuals with Crohn's Disease

A. Paterson, M. Silverberg, A. Griffiths, 2015, Inflammatory bowel diseases.

Acute cytomegalovirus infection in a child with Ménétrier's disease.

A. Griffiths, D. Eisenstat, B. Drumm, 1995, Gastroenterology.

Alterations in the gut microbiome of children with severe ulcerative colitis

Dan Turner, Adrienne Stolfi, A. Griffiths, 2012, Inflammatory bowel diseases.

Esophageal, gastric, and duodenal manifestations of IBD and the role of upper endoscopy in IBD diagnosis

A. Griffiths, D. Turner, 2007, Current gastroenterology reports.

Cost-effectiveness and Clinical Outcomes of Early Anti-Tumor Necrosis Factor-α Intervention in Pediatric Crohn's Disease.

A. Griffiths, T. Walters, S. Ito, 2019, Inflammatory bowel diseases.

Budesonide for maintenance of remission in Crohn's disease.

G. Kaplan, A. Griffiths, E. Benchimol, 2014, The Cochrane database of systematic reviews.

Enteral nutrition in children.

A. Griffiths, 1999, Nestle Nutrition workshop series. Clinical & performance programme.

Enteral feeding in inflammatory bowel disease

A. Griffiths, 2006, Current opinion in clinical nutrition and metabolic care.

Distinct and overlapping genetic loci in crohn's disease and ulcerative colitis: Correlations with pathogenesis

M. Silverberg, H. Steinhart, A. Griffiths, 2011, Inflammatory bowel diseases.

Development and Validation of a Pediatric MRI-Based Perianal Crohn Disease (PEMPAC) Index-A Report from the ImageKids Study.

A. Griffiths, M. Gavish, D. Turner, 2021, Inflammatory bowel diseases.

Assessing disease activity in ulcerative colitis: Patients or their physicians?

G. Guyatt, M. Silverberg, H. Steinhart, 2010, Inflammatory bowel diseases.

Associations Among Mucosal and Transmural Healing and Fecal Level of Calprotectin in Children With Crohn's Disease

A. Griffiths, T. Walters, D. Turner, 2018, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Factors influencing postoperative recurrence of Crohn's disease in childhood.

M. Corey, A. Griffiths, D. Wesson, 1991, Gut.

Simple Endoscopic Score of Crohn's disease and Magnetic Resonance Enterography in Children: Report from ImageKids study.

A. Griffiths, M. Amitai, M. Gavish, 2019, Journal of pediatric gastroenterology and nutrition.

Outcome Following Thiopurine Use in Children With Ulcerative Colitis: A Prospective Multicenter Registry Study

A. Griffiths, N. LeLeiko, A. Bousvaros, 2011, The American Journal of Gastroenterology.

Genetic profiling in inflammatory bowel disease: from association to bedside.

A. Griffiths, D. Philpott, J. V. van Limbergen, 2011, Gastroenterology.

Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course.

C. Huttenhower, E. Franzosa, H. Vlamakis, 2018, Cell host & microbe.

Pediatric Inflammatory Bowel Disease in the Emergency Department

A. Griffiths, J. V. Limbergen, 2010 .

Growth and clinical course of children with Crohn's disease.

J. H. MacMillan, A. Griffiths, P. Sherman, 1993, Gut.

Development of a machine-learning model to assess terminal ileum Endoscopic healing in pediatric Crohn's disease from Magnetic Resonance Enterography data

A. Griffiths, M. Freiman, D. Turner, 2021, medRxiv.

P128 Development of the Paediatric Inflammatory Crohn's MRE Index (PICMI)- results from the ImageKids Study

A. Griffiths, M. Gavish, R. Russell, 2018 .

P-046: Damage and inflammatory activity in pediatric Crohn’s disease (CD) based on radiologist and gastroenterologist physician global assessment

A. Griffiths, M. Amitai, T. Walters, 2014 .

Appraisal of the pediatric ulcerative colitis activity index (PUCAI)

A. Griffiths, N. LeLeiko, A. Bousvaros, 2009, Inflammatory bowel diseases.

A Simple Endoscopic Score Modified for the Upper Gastrointestinal Tract in Crohn’s Disease [UGI-SES-CD]: A Report From the ImageKids Study

A. Griffiths, J. Kelsen, M. Amitai, 2018, Journal of Crohn's & colitis.

Enteral feeding and Crohn disease

A. Griffiths, M. Zachos, 2001, Current opinion in gastroenterology.

Relationship of Common Laboratory Parameters to the Activity of Crohn's Disease in Children

A. Griffiths, A. Katz, Francine Mandel, 1992, Journal of pediatric gastroenterology and nutrition.

Supplementary enterai nutrition maintains remission in paediatric Crohn's disease

M. Corey, A. Griffiths, P. Pencharz, 1996 .

Immune response and barrier dysfunction-related proteomic signatures in preclinical phase of Crohn’s disease highlight earliest events of pathogenesis

P. Moayyedi, M. Silverberg, A. Griffiths, 2023, Gut.

Factors that influence the postoperative recurrence of Crohn’s disease in childhood

A. Griffiths, 1990 .

Endpoints for extraintestinal manifestations in inflammatory bowel disease trials: the EXTRA consensus from the International Organization for the Study of Inflammatory Bowel Diseases

S. Ng, C. O'Morain, A. Griffiths, 2022, The Lancet Gastroenterology & Hepatology.

Prioritizing Crohn’s disease genes by integrating association signals with gene expression implicates monocyte subsets

Mamta Giri, Ephraim Kenigsberg, Judy H. Cho, 2019, Genes & Immunity.

Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease.

M. Daly, R. Xavier, D. Cutler, 2018, Inflammatory bowel diseases.

Appraisal of the Pediatric Crohn's Disease Activity Index on Four Prospectively Collected Datasets: Recommended Cutoff Values and Clinimetric Properties

A. Griffiths, N. LeLeiko, T. Walters, 2010, The American Journal of Gastroenterology.

A Prospective Multicenter Study: Development and Validation of a Pediatric Ulcerative Colitis Activity Index

A. Griffiths, J. Bruijne, T. Walters, 2006 .

Clinical value of fecal calprotectin

A. Griffiths, A. Ricciuto, 2019, Critical reviews in clinical laboratory sciences.

Challenging Question: Can We Diagnose Crohn's Disease without Histology?

A. Griffiths, 2013, Digestive Diseases.

Advanced Techniques for Diagnosis of IBD

A. Griffiths, 2013 .

Enteral nutrition in the management of Crohn's disease.

A. Griffiths, 2005, JPEN. Journal of parenteral and enteral nutrition.

Erratum: Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study(Nature Genetics (2009) 41 (216220))

Judy H. Cho, K. Roeder, M. Daly, 2009 .

Sa1151 Steroid-Free Remission in Adalimumab-Treated Pediatric Patients With Moderately to Severely Active Crohn's Disease in the IMAgINE 1 Trial

A. Griffiths, S. Eichner, W. Crandall, 2014 .

Assessing activity of pediatric Crohn's disease: which index to use?

M. Corey, A. Griffiths, A. Otley, 1999, Gastroenterology.

Altered gut microbiome composition and function are associated with gut barrier dysfunction in healthy relatives of patients with Crohn's disease.

P. Moayyedi, A. Griffiths, A. Steinhart, 2022, Gastroenterology.

Utilization of Whole Exome Sequencing Data to Identify Clinically Relevant Pharmacogenomic Variants in Pediatric Inflammatory Bowel Disease

Arun K. Ramani, A. Griffiths, N. Warner, 2020, Clinical and translational gastroenterology.

Results of the 2nd scientific workshop of the ECCO (IV): therapeutic strategies to enhance intestinal healing in inflammatory bowel disease.

A. Griffiths, G. D'Haens, G. Van Assche, 2012, Journal of Crohn's & colitis.

Olsalazine versus sulfasalazine in mild to moderate childhood ulcerative colitis: results of the Pediatric Gastroenterology Collaborative Research Group Clinical Trial.

A. Griffiths, B. Kirschner, J. Watkins, 1993, Journal of pediatric gastroenterology and nutrition.

Impact-iii Is a Valid, Reliable and Responsive Measure of Health-related Quality of Life in Pediatric Crohn's Disease

A. Griffiths, A. Otley, A. Olson, 2006 .

The IMPACT Questionnaire: A Valid Measure of Health-Related Quality of Life in Pediatric Inflammatory Bowel Disease

A. Griffiths, D. Nicholas, A. Otley, 2002, Journal of pediatric gastroenterology and nutrition.

Corticosteroids for maintaining remission of Crohn's disease.

A. Griffiths, R. Modigliani, K. Ewe, 2001, The Cochrane database of systematic reviews.

Intestinal Ultrasound in Pediatric Inflammatory Bowel Disease: Promising, but Work in Progress

A. Griffiths, G. D'Haens, M. Benninga, 2021, Inflammatory bowel diseases.

Novel fecal biomarkers that precede clinical diagnosis of ulcerative colitis.

P. Moayyedi, G. Kaplan, M. Silverberg, 2020, Gastroenterology.

Crohn’s and Colitis Canada’s 2021 Impact of COVID-19 & Inflammatory Bowel Disease in Canada: A Knowledge Translation Strategy

G. Kaplan, A. Griffiths, A. Bitton, 2021, Journal of the Canadian Association of Gastroenterology.

The minimal detectable change cannot reliably replace the minimal important difference.

G. Guyatt, A. Griffiths, L. Griffith, 2010, Journal of clinical epidemiology.

Tufting enteropathy: a newly recognized clinicopathological entity associated with refractory diarrhea in infants.

A. Griffiths, P. Sherman, E. Cutz, 1994, Journal of pediatric gastroenterology and nutrition.

What really happens to people on long-term peritoneal dialysis?

Sheryl M. Davies, A. Griffiths, S. Davies, 1998, Kidney international.

Intervention for Growth Failure in Children with IBD

A. Griffiths, 2006 .

Outcome measures for clinical trials in paediatric IBD: an evidence-based, expert-driven practical statement paper of the paediatric ECCO committee

A. Griffiths, S. Vermeire, G. Veres, 2014, Gut.

Inflammatory Bowel Disease Among Canadian Children: Comparison Between Children of Non-European Descent and Children of European Descent.

G. Kaplan, A. Griffiths, E. Benchimol, 2023, Inflammatory bowel diseases.

Budesonide for the Induction and Maintenance of Remission in Crohn’s Disease: Systematic Review and Meta-Analysis for the Cochrane Collaboration

G. Kaplan, A. Griffiths, E. Benchimol, 2018, Journal of the Canadian Association of Gastroenterology.

Replication of genetic variation in the MYO9B gene in Crohn's disease.

M. Silverberg, A. Griffiths, V. Wolters, 2011, Human immunology.

Clinical Outcomes With Therapeutic Drug Monitoring in Inflammatory Bowel Disease: A Systematic Review With Meta-Analysis

A. Griffiths, T. Walters, P. Church, 2018, Journal of Crohn's & colitis.

Body mass index in children with newly diagnosed inflammatory bowel disease: observations from two multicenter North American inception cohorts.

A. Griffiths, N. LeLeiko, A. Bousvaros, 2007, The Journal of pediatrics.

Symptoms Do Not Correlate With Findings From Colonoscopy in Children With Inflammatory Bowel Disease and Primary Sclerosing Cholangitis

A. Griffiths, B. Kamath, T. Walters, 2018, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Struggles, strengths, and strategies: an ethnographic study exploring the experiences of adolescents living with an ostomy

A. Griffiths, D. Nicholas, T. Gerstle, 2008, Health and quality of life outcomes.

Asymptomatic Uveitis in Children with Chronic Inflammatory Bowel Diseases

A. Griffiths, P. Sherman, M. Marcon, 1993, Journal of pediatric gastroenterology and nutrition.

Analysis of the effects of increasing delivered dialysis treatment to malnourished peritoneal dialysis patients.

A. Griffiths, S. Davies, L. Phillips, 2000, Kidney international.

Impact of Peritoneal Membrane Function on Long Term Clinical Outcome in Peritoneal Dialysis Patients

A. Griffiths, S. Davies, L. Phillips, 1999, Peritoneal Dialysis International.

Concomitant Use of Immunomodulators Affects the Durability of Infliximab Therapy in Children With Crohn's Disease.

A. Griffiths, N. LeLeiko, A. Bousvaros, 2015, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

CONTRIBUTION OF SUSCEPTIBILITY GENES TO PEDIATRIC ONSET INFLAMMATORY BOWEL DISEASE: 204

M. Silverberg, A. Griffiths, T. Walters, 2005 .

Fecal Markers of Inflammation and Disease Activity in Paediatric Crohn's Disease: Results from the ImageKids Study.

A. Griffiths, M. Gavish, T. Walters, 2019, Journal of pediatric gastroenterology and nutrition.

Natural history of bone metabolism and bone mineral density in children with inflammatory bowel disease

A. Griffiths, G. Hawker, F. Sylvester, 2007, Inflammatory bowel diseases.

A Critical Assessment of Items on the Pediatric Crohn's Disease Activity Index

A. Griffiths, H. Derkx, M. Merkus, 2003, Journal of pediatric gastroenterology and nutrition.

Anti-microbial antibody response is associated with future onset of Crohn's disease independent of biomarkers of altered gut barrier function, subclinical inflammation, and genetic risk.

A. Paterson, P. Moayyedi, M. Silverberg, 2021, Gastroenterology.

A Review of Activity Indices and End Points for Clinical Trials in Children with Crohn's Disease

A. Griffiths, A. Bousvaros, B. Feagan, 2005, Inflammatory bowel diseases.

Pediatric Crohn Disease Activity Index: Responsive to Short-term Change

A. Griffiths, A. Otley, D. Stephens, 2003, Journal of pediatric gastroenterology and nutrition.

Repeated doses of porcine secretin in the treatment of autism: a randomized, placebo-controlled trial.

A. Griffiths, G. Koren, B. Mackinnon, 2001, Pediatrics.

Associations of NOD2 polymorphisms with Erysipelotrichaceae in stool of in healthy first degree relatives of Crohn’s disease subjects

A. Paterson, P. Moayyedi, M. Silverberg, 2020, BMC medical genetics.

P0719 EPIDEMIOLOGY OF PEDIATRIC IBD IN THE GREATER TORONTO AREA

A. Griffiths, T. Walters, P. Sherman, 2004 .

Prospective Evaluation of Endoscopic and Histologic Indices in Pediatric Ulcerative Colitis Using Centralized Review

A. Griffiths, E. Benchimol, T. Walters, 2021, The American journal of gastroenterology.

Ustekinumab in Paediatric Patients with Moderately to Severely Active Crohn’s Disease: Pharmacokinetics, Safety, and Efficacy Results from UniStar, a Phase 1 Study

A. Griffiths, D. Turner, J. Rosh, 2021, Journal of Crohn's & colitis.

Five-year incidence of surgery in a prospectively followed cohort of pediatric patients with Crohnʼs Disease: P-0069.

A. Griffiths, J. Machan, A. Bousvaros, 2009 .

A Comparison of Preference-Based, Generic and Disease-Specific Health-Related Quality of Life in Pediatric Inflammatory Bowel Disease

A. Griffiths, T. Walters, A. Otley, 2023, Journal of the Canadian Association of Gastroenterology.

An Assessment of the Validity and Reliability of the Pediatric Child Health Utility 9D in Children with Inflammatory Bowel Disease

A. Griffiths, T. Walters, W. Ungar, 2021, Children.

Clinical disease activity and endoscopic severity correlate poorly in children newly diagnosed with Crohn's disease.

A. Griffiths, E. Benchimol, T. Walters, 2019, Gastrointestinal endoscopy.

Magnetic resonance enterography has good inter-rater agreement and diagnostic accuracy for detecting inflammation in pediatric Crohn disease

A. Griffiths, B. Feldman, T. Walters, 2017, Pediatric Radiology.

Abnormal Liver Biochemistry Is Common in Pediatric Inflammatory Bowel Disease: Prevalence and Associations

A. Griffiths, B. Feldman, B. Kamath, 2015, Inflammatory bowel diseases.

Mathematical weighting of a clinimetric index (Pediatric Ulcerative Colitis Activity Index) was superior to the judgmental approach.

A. Griffiths, D. Beaton, A. Otley, 2009, Journal of clinical epidemiology.

Intensified infliximab induction is associated with improved response and decreased colectomy in steroid-refractory paediatric ulcerative colitis.

A. Griffiths, T. Walters, P. Church, 2019, Journal of Crohn's & colitis.

Human autoinflammatory disease reveals ELF4 as a transcriptional regulator of inflammation

A. Griffiths, N. Warner, W. Ji, 2021, Nature Immunology.

Benefits and Risks of Combining Anti-tumor Necrosis Factor with Immunomodulator Therapy in Pediatric Inflammatory Bowel Disease

A. Griffiths, D. Turner, J. Escher, 2015, Inflammatory bowel diseases.

Vitamin D deficiency enhances expression of autophagy-regulating miR-142-3p in mouse and 'involved' IBD patient intestinal tissues.

A. Griffiths, D. Philpott, T. Walters, 2021, American journal of physiology. Gastrointestinal and liver physiology.

P192 - Disease duration does not affect outcome following infliximab therapy in children with Crohn's disease

A. Griffiths, R. Baldassano, S. Kugathasan, 2009 .

Clinical and Host Biological Factors Predict Colectomy Risk in Children Newly Diagnosed With Ulcerative Colitis.

A. Griffiths, G. Gibson, R. Baldassano, 2021, Inflammatory bowel diseases.

Variation in Care in the Management of Children With Crohn's Disease: Data From a Multicenter Inception Cohort Study.

A. Griffiths, R. Baldassano, M. Dubinsky, 2019, Inflammatory bowel diseases.

health administrative data bowel disease in Ontario, Canada: evidence from Increasing incidence of paediatric inflammatory

A. Griffiths, L. Rabeneck, A. Guttmann, 2009 .

Type I interferons for induction of remission in ulcerative colitis.

A. Griffiths, R. Panaccione, E. Benchimol, 2015, The Cochrane database of systematic reviews.

Abdominal X-ray in Pediatric Acute Severe Colitis and Radiographic Predictors of Response to Intravenous Steroids

A. Griffiths, D. Turner, D. Mack, 2016, Journal of pediatric gastroenterology and nutrition.

Histologic Correlates of Clinical and Endoscopic Severity in Children Newly Diagnosed With Ulcerative Colitis

A. Griffiths, R. Baldassano, N. LeLeiko, 2017, The American journal of surgical pathology.

Enhanced Contribution of HLA in Pediatric Onset Ulcerative Colitis.

David T. Okou, D. Cutler, A. Griffiths, 2018, Inflammatory bowel diseases.

Transition of the patient with inflammatory bowel disease from pediatric to adult care: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition.

A. Griffiths, R. Baldassano, J. Markowitz, 2002, Journal of pediatric gastroenterology and nutrition.

Subcutaneous Golimumab in Pediatric Ulcerative Colitis: Pharmacokinetics and Clinical Benefit

A. Griffiths, M. Heyman, D. Turner, 2017, Inflammatory bowel diseases.

Infliximab-Induced Psoriasis and Psoriasiform Skin Lesions in Pediatric Crohn Disease and a Potential Association With IL-23 Receptor Polymorphisms

A. Griffiths, M. Tabbers, T. Walters, 2013, Journal of pediatric gastroenterology and nutrition.

P-0018: Severe neutropenia following a single infliximab infusion in a child with Crohn disease

A. Griffiths, M. Kirby-Allen, M. Sherlock, 2009 .

Age-of-Diagnosis Dependent Ileal Immune Intensification and Reduced Alpha-Defensin in Older versus Younger Pediatric Crohn Disease Patients despite Already Established Dysbiosis

Ajay S. Gulati, C. Huttenhower, R. Xavier, 2018, Mucosal Immunology.

More on lymphoproliferative disorders associated with crohn disease treatments.

A. Griffiths, 2013, Journal of Pediatric Gastroenterology and Nutrition - JPGN.

Monitoring of azathioprine/6-mercaptopurine treatment in children with IBD is not necessary.

A. Griffiths, 2003, Inflammatory bowel diseases.

Corticosteroid Dosing in Pediatric Acute Severe Ulcerative Colitis: A Propensity Score Analysis

A. Griffiths, N. LeLeiko, D. Turner, 2016, Journal of pediatric gastroenterology and nutrition.

Gene Expression Changes Associated with Resistance to Intravenous Corticosteroid Therapy in Children with Severe Ulcerative Colitis

M. Silverberg, A. Griffiths, P. Hu, 2010, PloS one.

The IBD and PSC Phenotypes of PSC-IBD

A. Griffiths, B. Kamath, A. Ricciuto, 2018, Current Gastroenterology Reports.

Can MR enterography screen for perianal disease in pediatric inflammatory bowel disease?

A. Griffiths, R. Moineddin, T. Walters, 2018, Journal of magnetic resonance imaging : JMRI.

Tu1962 Looking Beyond Symptoms and Disease Activity to Define Disease Severity in Inflammatory Bowel Disease: Results of an IOIBD Specialist Panel

S. Ng, C. O'Morain, M. Silverberg, 2016 .

Accurate classification of pediatric colonic IBD subtype using a random forest machine learning classifier.

A. Griffiths, L. Erdman, T. Walters, 2020, Journal of pediatric gastroenterology and nutrition.

Liver Enzyme Elevations Within 3 Months of Diagnosis of Inflammatory Bowel Disease and Likelihood of Liver Disease

A. Griffiths, N. LeLeiko, A. Goyal, 2014, Journal of pediatric gastroenterology and nutrition.

CARD15 and HLA DRB1 Alleles Influence Susceptibility and Disease Localization in Crohn's Disease

M. Silverberg, Z. Cohen, R. McLeod, 2004, American Journal of Gastroenterology.

INFLIXIMAB THERAPY RESTORES NORMAL GROWTH IN CHILDREN WITH CHRONICALLY ACTIVE SEVERE CROHN DISEASE REFRACTORY TO IMMUNOMODULATORY THERAPY: PG2-17

A. Griffiths, T. Walters, A. Gilman, 2005 .

Protein-Tyrosine Phosphatase Sigma Is Associated with Ulcerative Colitis

M. Silverberg, A. Griffiths, R. Duerr, 2007, Current Biology.

Phenotypic Evolution of Pediatric Inflammatory Bowel Disease Using the New Paris Classification

A. Griffiths, T. Walters, M. Sherlock, 2011 .

Slow‐Release 5‐Aminosalicylic Acid Therapy in Children with Small Intestinal Crohn's Disease

A. Griffiths, F. Sylvester, S. Koletzko, 1993, Journal of pediatric gastroenterology and nutrition.

Thiopurine Monotherapy in Paediatric Inflammatory Bowel Disease: 20 Years After Markowitz.

A. Griffiths, D. Wilson, 2020, Journal of pediatric gastroenterology and nutrition.

833 Malignancies in Children Receiving Infliximab and Other Inflammatory Bowel Disease Therapies: An Inflammatory Bowel Disease Multicenter, Prospective, Long-Term Registry of Pediatric Patients (Develop) Registry Data

A. Griffiths, R. Baldassano, M. Dubinsky, 2013 .

Utility of Neutrophil Fc&ggr; Receptor I (CD64) Index as a Biomarker for Mucosal Inflammation in Pediatric Crohn's Disease

A. Griffiths, R. Baldassano, S. Kugathasan, 2014, Inflammatory bowel diseases.

Paneth cell marker CD24 in NOD2 knockout organoids and in inflammatory bowel disease (IBD)

H. Drummond, J. Satsangi, A. Griffiths, 2013, Gut.

Maintenance Golimumab Treatment in Pediatric UC Patients With Moderately to Severely Active UC: PURSUIT PEDS PK Long-Term Study Results

A. Griffiths, J. Lynch, M. Heyman, 2020, Crohn's & colitis 360.

Inflammatory bowel disease in children in sub-Saharan Africa

A. Griffiths, D. Epstein, G. Watermeyer, 2020, Paediatrics and international child health.

138 Effect of Deep Ulceration at Diagnostic Colonoscopy on Initial Therapy and One Year Outcome in Children With Crohn's Disease

A. Griffiths, R. Baldassano, M. Dubinsky, 2012 .

Sa1884 Infliximab Versus Immunomodulator as First Maintenance Therapy in Children With Crohn Disease

A. Griffiths, N. LeLeiko, A. Bousvaros, 2012 .

Using the entire cohort in the receiver operating characteristic analysis maximizes precision of the minimal important difference.

G. Guyatt, A. Griffiths, L. Griffith, 2009, Journal of clinical epidemiology.

Mediterranean-like dietary pattern associations with gut microbiome composition and sub-clinical gastrointestinal inflammation.

A. Paterson, P. Moayyedi, M. Silverberg, 2022, Gastroenterology.

Corrigendum. Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature.

Timothy L. Tickle, C. Huttenhower, D. Gevers, 2015, Journal of Clinical Investigation.

Type I interferons for induction of remission in ulcerative colitis.

A. Griffiths, E. Benchimol, A. Steinhart, 2008, The Cochrane database of systematic reviews.

MACHINE LEARNING FOR CROHN’S DISEASE PHENOTYPE MODELING USING BIOPSY IMAGES

Ajay S. Gulati, Stanley N Cohen, C. Moskaluk, 2021, Gastroenterology.

Use of LARA-urea breath test in the diagnosis of Helicobacter pylori infection in children and adolescents: a preliminary study.

A. Griffiths, A. Otley, A. Day, 2003, Canadian journal of gastroenterology = Journal canadien de gastroenterologie.

PTU-092 Crohn's disease associated NOD2 variants show differential activation of NF-κb in response to auto-signalling and muramyl dipeptide

A. Griffiths, D. Philpott, S. Girardin, 2012, Gut.

P204 Endotrophin (PRO-C6) is associated with MRE confirmed intestinal strictures and Protein FingerPrint biomarkers of collagen degradation is associated with ulcerations in paediatric Crohn’s disease patients – results from the ImageKids study

A. Griffiths, R. Baldassano, P. Church, 2022, Journal of Crohn's and Colitis.

Imputing missing patient-level data and propensity score matching in cost-effectiveness analysis in Crohn's disease

A. Griffiths, T. Walters, S. Ito, 2021, Expert review of pharmacoeconomics & outcomes research.

3.18 Enteral nutrition for paediatric inflammatory bowel disease.

A. Griffiths, M. Mouzaki, 2015, World review of nutrition and dietetics.

P-0047: Low income children with Inflammatory Bowel Disease have higher surgical and hospitalization rates in a Universal Health Care System

T. To, A. Griffiths, L. Rabeneck, 2009 .

W1219 Retrospective Evaluation of the Safety and Effect of Adalimumab Therapy (Reseat) in Pediatric Crohn's Disease

A. Griffiths, S. Kugathasan, J. Rosh, 2008 .

Free and Bioavailable 25-Hydroxyvitamin D Concentrations are Associated With Disease Activity in Pediatric Patients With Newly Diagnosed Treatment Naïve Ulcerative Colitis.

A. Griffiths, R. Baldassano, N. LeLeiko, 2018, Inflammatory bowel diseases.

Multiple endocrine neoplasia IIb: an unusual cause of chronic constipation.

A. Griffiths, D. Stringer, R. Byard, 1990, The Journal of pediatrics.

Genetic variants and pathways implicated in a pediatric inflammatory bowel disease cohort

M. Daly, D. Cutler, A. Griffiths, 2018, Genes & Immunity.

Lifestyle Issues in Children and Adolescents with Chronic Inflammatory Bowel Diseases

A. Griffiths, P. Sherman, M. Marcon, 1990 .

Prevalence of NOD2/CARD15 mutations in pediatric IBD

M. Silverberg, A. Griffiths, P. Sherman, 2003 .

A comparison of the Child Health Utility 9D and the Health Utilities Index for estimating health utilities in pediatric inflammatory bowel disease

A. Griffiths, T. Walters, A. Otley, 2023, Quality of Life Research.

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

Judy H. Cho, C. Gieger, H. Hakonarson, 2015 .

Response to corticosteroids in severe ulcerative colitis: a systematic review of the literature and a meta-regression.

A. Griffiths, C. Walsh, A. Steinhart, 2007, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Response to corticosteroids in severe ulcerative colitis: a systematic review of the literature and a meta-regression.

A. Griffiths, C. Walsh, A. Steinhart, 2007, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Recommendations for Standardizing MRI-based Evaluation of Perianal Fistulizing Disease Activity in Pediatric Crohn's Disease Clinical Trials.

A. Griffiths, M. Gee, J. Fletcher, 2023, Inflammatory bowel diseases.

Title : Fecal microbial transplantation for pediatric ulcerative colitis : are we there yet ? Invited Commentary on : Fecal microbial transplant in children with ulcerative colitis , randomized double blinded placebo-controlled pilot study

A. Griffiths, E. Wine, 2017 .

Consensus for managing acute severe ulcerative colitis in children: a systematic review and joint statement from ECCO, ESPGHAN, and the Porto IBD Working Group of ESPGHAN.

A. Griffiths, R. Baldassano, M. Dubinsky, 2011, The American journal of gastroenterology.

Difficult-to-treat inflammatory bowel disease: results from an international consensus meeting.

C. O'Morain, A. Griffiths, L. Peyrin-Biroulet, 2023, The lancet. Gastroenterology & hepatology.

P0712 RE-EVALUATION OF THE PEDIATRIC CROHN???S DISEASE ACTIVITY INDEX: USEFULNESS IN THE PRACTICE SETTING

A. Griffiths, A. Katz, A. Bousvaros, 2004 .

IMPACT-II QOL questionnaire: Performance in new-onset pediatric IBD patients (the pediatric IBD collaborative registry)

A. Griffiths, A. Katz, S. Kugathasan, 2003 .

The Continental Divide: Anti-TNF Use in Pediatric IBD Is Different in North America Compared to Other Parts of the World

A. Griffiths, D. Turner, J. Hyams, 2018, Canadian journal of gastroenterology & hepatology.

T1745 A Prospective Multicenter Study of Outcomes and Predictors of Response in Severe Pediatric Ulcerative Colitis

M. Silverberg, A. Griffiths, N. LeLeiko, 2009 .

DOP039 Development of MRE based multi item measures of inflammation and intestinal damage in paediatric Crohn's disease: the ImageKids study

A. Griffiths, M. Amitai, T. Walters, 2014 .

Antineutrophil cytoplasmic antibodies and anti-Saccharomyces cerevisiae antibody: clinical tools or clues for research?

A. Griffiths, M. Zachos, 2000, Journal of Pediatric Gastroenterology and Nutrition - JPGN.

The 2023 Impact of Inflammatory Bowel Disease in Canada: Special Populations—Children and Adolescents with IBD

G. Kaplan, A. Griffiths, A. Bitton, 2023, Journal of the Canadian Association of Gastroenterology.

Induction and Maintenance Adalimumab Therapy for the Treatment of Moderate to Severe Crohn's Disease in Children

A. Griffiths, R. Baldassano, M. Dubinsky, 2011 .

PATTERNS OF INFLIXIMAB USE IN CHILDREN WITH CROHN DISEASE

A. Griffiths, A. Bousvaros, S. Kugathasan, 2006 .

Targeted Assessment of Mucosal Immune Gene Expression Predicts Clinical Outcomes in Children with Ulcerative Colitis.

A. Griffiths, R. Baldassano, A. Jegga, 2022, Journal of Crohn's & Colitis.

A182 PREDICTING HIGH DIRECT HEALTHCARE COSTS IN PEDIATRIC PATIENTS WITH INFLAMMATORY BOWEL DISEASE IN THE FIRST YEAR FOLLOWING DIAGNOSIS

G. Kaplan, A. Griffiths, E. Benchimol, 2023, Journal of the Canadian Association of Gastroenterology.

A42 HETEROGENEITY IN EFFICACY AND SAFETY ENDPOINTS FOR PEDIATRIC CLINICAL TRIALS IN INFLAMMATORY BOWEL DISEASE: A NEED FOR HARMONIZATION

A. Griffiths, B. Feagan, Rilla Schneider, 2022, Gastroenterology.

ORAL TACROLIMUS TREATMENT OF SEVERE COLITIS IN CHILDREN: LONG-TERM FOLLOWUP

A. Griffiths, B. Kirschner, A. Bousvaros, 1998 .

Infliximab-induced psoriasis in pediatric Crohn Disease; Experience of this paradoxical event at a tertiary centre: P-0043.

A. Griffiths, M. Sherlock, K. Frost, 2008 .

Variants in nicotinamide adenine dinucleotide phosphate oxidase complex components determine susceptibility to very early onset inflammatory bowel disease.

M. Silverberg, A. Griffiths, S. Baksh, 2014, Gastroenterology.

Glucocorticoid bioactivity does not predict response to steroid therapy in severe pediatric ulcerative colitis

M. Silverberg, A. Griffiths, N. LeLeiko, 2010, Inflammatory bowel diseases.

Severe Ulcerative Colitis After Rituximab Therapy

A. Griffiths, T. Gonska, E. Harvey, 2010, Pediatrics.

Infliximab-Induced Psoriasis and Psoriasiform Skin Lesions in Pediatric Crohn Disease and a Potential Association With IL-23 Receptor Polymorphisms

A. Griffiths, M. Tabbers, T. Walters, 2013, Journal of pediatric gastroenterology and nutrition.

Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn's disease.

A. Griffiths, J. Hugot, G. Veres, 2014, Journal of Crohn's & colitis.

Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases

John J. Connolly, J. Glessner, H. Hakonarson, 2015, Nature Medicine.

Consensus statements on the risk, prevention, and treatment of venous thromboembolism in inflammatory bowel disease: Canadian Association of Gastroenterology.

A. Griffiths, A. Bitton, C. Bernstein, 2014, Gastroenterology.

A. Griffiths, G. Veres, C. Strisciuglio, 2018, Journal of pediatric gastroenterology and nutrition.

Genetic profiling in inflammatory bowel disease: from association to bedside.

A. Griffiths, D. Philpott, J. V. van Limbergen, 2011, Gastroenterology.

P515 Manipulating the microbiome in paediatric acute severe colitis with a cocktail of antibiotics: A pilot randomised controlled trial

M. Yassour, H. Vlamakis, R. Xavier, 2018 .

Stratification of risk of progression to colectomy in ulcerative colitis via measured and predicted gene expression.

A. Kasarskis, A. Griffiths, G. Gibson, 2021, American journal of human genetics.

Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases

J. Glessner, H. Hakonarson, Cecilia Kim, 2015, Nature Medicine.

Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases

John J. Connolly, J. Glessner, H. Hakonarson, 2015, Nature Medicine.

Increasing incidence of paediatric inflammatory bowel disease in Ontario, Canada: evidence from health administrative data

T. To, A. Griffiths, L. Rabeneck, 2009, Gut.

Abnormal Liver Biochemistry Is Common in Pediatric Inflammatory Bowel Disease: Prevalence and Associations

A. Griffiths, B. Feldman, B. Kamath, 2015, Inflammatory bowel diseases.

O-16: MRE cannot replace gastroscopy (EGD) in assessing the upper gastrointestinal tract in pediatric Crohn’s disease (CD): results from the ImageKids study

A. Griffiths, T. Walters, D. Turner, 2014 .

Falk Symposium Series

Claudio Fiocchi, Peter L. Lakatos, Ashwin N. Ananthakrishnan, 2009, Digestive Diseases.

Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study

M. Schirmer, A. Griffiths, G. Gibson, 2019, The Lancet.

Gut Microbiome Composition is associated with future onset of Crohn's Disease in Healthy First-Degree Relatives.

P. Moayyedi, M. Silverberg, A. Griffiths, 2023, Gastroenterology.

Safety and efficacy of maintenance infliximab therapy for moderate-to-severe Crohn’s disease in children: REACH open-label extension

A. Griffiths, R. Baldassano, S. Kugathasan, 2011, Current medical research and opinion.

Mucosal Expression of Type 2 and Type 17 Immune Response Genes Distinguishes Ulcerative Colitis From Colon-Only Crohn's Disease in Treatment-Naive Pediatric Patients.

A. Griffiths, R. Baldassano, N. LeLeiko, 2017, Gastroenterology.

Mutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease.

E. Schadt, A. Griffiths, C. Klein, 2014, Gastroenterology.

Engaging Patients and Caregivers in Research for Pediatric IBD: Top 10 Research Priorities.

A. Laupacis, A. Griffiths, Kate Murray, 2019, Journal of pediatric gastroenterology and nutrition.

CROHN'S DISEASE IN CHILDREN AND ADOLESCENTS : WHAT ARE THE TREATMENT OPTIONS?

A. Griffiths, 1999 .

Fibronectin andimmunecomplexes inrheumatic diseases

A. Griffiths, J. Coppock, K. Herbert, 1987 .

Explorer Single Nucleotide Polymorphisms That Increase Expression of the Guanosine Triphosphatase RAC 1 Are Associated With Ulcerative Colitis

A. Paterson, C. Lees, J. Satsangi, 2011 .