C. Cameron

发表

Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population

M. Vignuzzi, J. Stone, J. Arnold, 2006, Nature.

Evidence for a functional role of the dynamics of glycine-121 of Escherichia coli dihydrofolate reductase obtained from kinetic analysis of a site-directed mutant.

C. Cameron, S. Benkovic, S J Benkovic, 1997, Biochemistry.

Arrest of human mitochondrial RNA polymerase transcription by the biological aldehyde adduct of DNA, M1dG

J. Arnold, C. Cameron, L. Marnett, 2010, Nucleic acids research.

The Stem-Loop I of Senecavirus A IRES Is Essential for Cap-Independent Translation Activity and Virus Recovery

C. Cameron, Nan Wang, Li Yu, 2021, Viruses.

Structure-Function Relationships of the Viral RNA-dependent RNA Polymerase

C. Cameron, V. S. Korneeva, 2007, Journal of Biological Chemistry.

Small ubiquitin-like modifying protein isopeptidase assay based on poliovirus RNA polymerase activity.

J. Arnold, C. Cameron, D. Sterner, 2006, Analytical biochemistry.

Production of "authentic" poliovirus RNA-dependent RNA polymerase (3D(pol)) by ubiquitin-protease-mediated cleavage in Escherichia coli.

Thomas J. Wisniewski, J. Arnold, C. Cameron, 1999, Protein expression and purification.

Multiple poliovirus-induced organelles suggested by comparison of spatiotemporal dynamics of membranous structures and phosphoinositides

G. Ning, J. Arnold, C. Cameron, 2018, PLoS pathogens.

Stimulation of Poliovirus Synthesis in a HeLa Cell-Free In Vitro Translation-RNA Replication System by Viral Protein 3CDpro

C. Cameron, A. Paul, E. Wimmer, 2005, Journal of Virology.

Molecular and Biological Characterization of Deformed Wing Virus of Honeybees (Apis mellifera L.)

C. Cameron, S. Camazine, M. B. Boniotti, 2006, Journal of Virology.

Hepatitis C Virus RNA-dependent RNA Polymerase (NS5B) as a Mediator of the Antiviral Activity of Ribavirin*

C. Cameron, Z. Hong, David Maag, 2001, The Journal of Biological Chemistry.

HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A-cyclophilin A interaction to cyclophilin inhibitors.

C. Cameron, F. Chisari, P. Gallay, 2010, Journal of hepatology.

Programming the Rous Sarcoma Virus Protease to Cleave New Substrate Sequences (*)

A Wlodawer, C. Cameron, A. Wlodawer, 1996, The Journal of Biological Chemistry.

Human Immunodeficiency Virus, Type 1 Protease Substrate Specificity Is Limited by Interactions between Substrate Amino Acids Bound in Adjacent Enzyme Subsites (*)

A Wlodawer, C. Cameron, A. Wlodawer, 1996, The Journal of Biological Chemistry.

The Palm Subdomain-based Active Site is Internally Permuted in Viral RNA-dependent RNA Polymerases of an Ancient Lineage

C. Cameron, B. Luke, A. Gorbalenya, 2002, Journal of Molecular Biology.

An on-chip, multichannel droplet sorter using standing surface acoustic waves.

Tony Jun Huang, Sz-Chin Steven Lin, Xiaoyun Ding, 2013, Analytical chemistry.

Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective

J. Arnold, C. Cameron, S. Almo, 2021, eLife.

Inhibition of SARS-CoV-2 polymerase by nucleotide analogs: a single molecule perspective

J. Arnold, C. Cameron, S. Almo, 2020, bioRxiv : the preprint server for biology.

Microfluidic opportunities in the field of nutrition.

Tony Jun Huang, Sixing Li, C. Cameron, 2013, Lab on a chip.

Effects of BMS-986094, a Guanosine Nucleotide Analogue, on Mitochondrial DNA Synthesis and Function.

J. Arnold, C. Cameron, O. Flint, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

Unexpected sequences and structures of mtDNA required for efficient transcription from the first heavy-strand promoter

J. Arnold, C. Cameron, Divakaran Murugesapillai, 2017, bioRxiv.

Structural models of mammalian mitochondrial transcription factor B2.

C. Cameron, N. Yennawar, A. Uchida, 2015, Biochimica et biophysica acta.

Title Hijacking of multiple phospholipid biosynthetic pathways and induction of membrane biogenesis by a picornaviral 3 CD protein

G. Ning, C. Cameron, Y. Hara, 2019 .

Hijacking of multiple phospholipid biosynthetic pathways and induction of membrane biogenesis by a picornaviral 3CD protein

G. Ning, C. Cameron, Y. Hara, 2017, bioRxiv.

Hijacking of Multiple Phospholipid Biosynthetic Pathways and Induction of Membrane Biogenesis by a Picornaviral 3CD Protein

C. Cameron, Y. Hara, Robert Y. L. Wang, 2017, bioRxiv.

Interferon and Ribavirin Combination Treatment Synergistically Inhibit HCV Internal Ribosome Entry Site Mediated Translation at the Level of Polyribosome Formation

C. Cameron, R. Garry, S. Hazari, 2013, PloS one.

Viral genome replication

C. Cameron, K. Raney, M. Götte, 2009 .

Predicting Off‐Target Effects of Therapeutic Antiviral Ribonucleosides

J. Arnold, C. Cameron, 2018 .

Sensitivity of Mitochondrial Transcription and Resistance of RNA Polymerase II Dependent Nuclear Transcription to Antiviral Ribonucleosides

J. Arnold, C. Cameron, A. Gnatt, 2012, PLoS pathogens.

Control of Template Positioning during de Novo Initiation of RNA Synthesis by the Bovine Viral Diarrhea Virus NS5B Polymerase*

C. Cameron, J. Deval, M. Götte, 2006, Journal of Biological Chemistry.

A novel mechanism to ensure terminal initiation by hepatitis C virus NS5B polymerase.

C. Cameron, Z. Hong, W. Zhong, 2001, Virology.

Mutational analysis of the substrate binding pockets of the Rous sarcoma virus and human immunodeficiency virus-1 proteases.

C. Cameron, A. Wlodawer, I. Weber, 1994, The Journal of biological chemistry.

Poliovirus Infection Transiently Increases COPII Vesicle Budding

C. Cameron, J. Hay, H. Oh, 2012, Journal of Virology.

Poliovirus Infection Transiently Increases Copii Vesicle Budding 6

C. Cameron, J. Hay, H. Oh, 2012 .

The RNA-binding site of poliovirus 3C protein doubles as a phosphoinositide-binding domain

C. Cameron, D. Boehr, M. Buck, 2017, bioRxiv.

TARGETING THE NS5A PROTEIN OF HCV: AN EMERGING OPTION.

C. Cameron, W. Kazmierski, D. Cordek, 2011, Drugs of the future.

Inhibition of dengue virus replication by mycophenolic acid and ribavirin.

C. Cameron, R. Padmanabhan, S. Ubol, 2006, The Journal of general virology.

The 3′ Untranslated Regions of Influenza Genomic Sequences Are 5′PPP-Independent Ligands for RIG-I

C. Cameron, P. Ranjan, T. Fujita, 2012, PloS one.

Uncovering modeling features of viral replication dynamics from high-throughput single-cell virology experiments

Ashley I. Teufel, C. Wilke, J. Draghi, 2020, bioRxiv.

MutagenesisSensitivity to Lethal Mutational Robustness of an RNA Virus

M. Vignuzzi, C. Cameron, Jason D Graci, 2013 .

Synthesis of a Universal 5‐Nitroindole Ribonucleotide and Incorporation into RNA by a Viral RNA‐Dependent RNA Polymerase

C. Cameron, B. Peterson, D. Harki, 2007, Chembiochem : a European journal of chemical biology.

Challenges for the Development of Ribonucleoside Analogues as Inducers of Error Catastrophe

C. Cameron, Jason D Graci, 2004, Antiviral chemistry & chemotherapy.

Single-nucleotide resolution of RNA strands in the presence of their RNA complements.

S. Ghosh, J. Arnold, C. Cameron, 1999, BioTechniques.

Cytoplasmic Viral RNA-Dependent RNA Polymerase Disrupts the Intracellular Splicing Machinery by Entering the Nucleus and Interfering with Prp8

C. Cameron, Hsuan Liu, R. Kuo, 2014, PLoS pathogens.

Interfering with nucleotide excision by the coronavirus 3′-to-5′ exoribonuclease

J. Arnold, C. Cameron, D. Dulin, 2022, bioRxiv.

Synthesis of a 6-methyl-7-deaza analogue of adenosine that potently inhibits replication of polio and dengue viruses.

C. Cameron, E. Smidansky, B. Peterson, 2010, Journal of medicinal chemistry.

One-pot synthesis of nucleoside 5'-triphosphates from nucleoside 5'-H-phosphonates.

C. Cameron, E. Smidansky, B. Peterson, 2008, Organic letters.

Purification and characterization of human immunodeficiency virus type 1 reverse transcriptase.

C. Cameron, S. Benkovic, S. L. Le Grice, 1995, Methods in enzymology.

The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent

J. Arnold, C. Cameron, E. Snijder, 2011, Nucleic Acids Research.

Enteroviral 2C protein is an RNA-stimulated ATPase and uses a two-step mechanism for binding to RNA and ATP

J. Arnold, C. Cameron, N. Yennawar, 2022, bioRxiv.

The Pennsylvania State University The Graduate School Department of Biochemistry and Molecular Biology CHARACTERIZATION OF FA/FB-CONTAINING PROTEINS PshBI AND PshBII IN THE PHOTOSYNTHETIC REACTION CENTER OF Heliobacterium modesticaldum A Thesis in Biochemistry and Molecular Biology by

C. Cameron, D. Bryant, P. Berg, 2022 .

Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases.

C. Cameron, B. Peterson, D. Harki, 2006, Journal of medicinal chemistry.

Synthesis and antiviral evaluation of a mutagenic and non-hydrogen bonding ribonucleoside analogue: 1-beta-D-Ribofuranosyl-3-nitropyrrole.

C. Cameron, Saikat Ghosh, B. Peterson, 2002, Biochemistry.

2′-C-methylated nucleotides terminate virus RNA synthesis by preventing active site closure of the viral RNA-dependent RNA polymerase

J. Arnold, C. Cameron, H. Oh, 2019, The Journal of Biological Chemistry.

Proteinase-Polymerase Precursor as the Active Form of Feline Calicivirus RNA-Dependent RNA Polymerase

C. Cameron, Lai Wei, H. Pathak, 2001, Journal of Virology.

PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions.

C. Cameron, P. Cremer, Djoshkun Shengjuler, 2017, Journal of visualized experiments : JoVE.

IRES-independent, eIF2A/eIF2D-dependent translation of the enterovirus genome

J. Arnold, C. Cameron, Hyejeong Kim, 2022, bioRxiv.

An assembly domain of the Rous sarcoma virus Gag protein required late in budding

C. Cameron, J. Wills, C. Wilson, 1994, Journal of virology.

Fine mapping and characterization of the Rous sarcoma virus Pr76gag late assembly domain

C. Cameron, J. Wills, J. Leis, 1996, Journal of virology.

Induced intra- and intermolecular template switching as a therapeutic mechanism against RNA viruses.

M. Vignuzzi, J. Arnold, C. Cameron, 2021, Molecular cell.

Viperin Reveals Its True Function.

J. Arnold, C. Cameron, S. Almo, 2020, Annual review of virology.

Mitochondrial gene expression.

C. Cameron, S. D. Cline, 2012, Biochimica et biophysica acta.

Stimulation of poliovirus RNA synthesis and virus maturation in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDpro

C. Cameron, A. Paul, E. Wimmer, 2005, Virology Journal.

Cystoviral polymerase complex protein P7 uses its acidic C-terminal tail to regulate the RNA-directed RNA polymerase P2.

Hsin Wang, J. Arnold, C. Cameron, 2014, Journal of molecular biology.

The ZCCHC14/TENT4 complex is required for hepatitis A virus RNA synthesis

C. Cameron, S. Lemon, D. McGivern, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Structure-Function Relationships of the Viral RNA-dependent RNA Polymerase

C. Cameron, V. S. Korneeva, 2007, Journal of Biological Chemistry.

Human Rhinovirus Type 14 Gain-of-Function Mutants for oriI Utilization Define Residues of 3C(D) and 3Dpol That Contribute to Assembly and Stability of the Picornavirus VPg Uridylylation Complex

J. Arnold, C. Cameron, S. Lemon, 2007, Journal of Virology.

Structure-Function Relationships of the RNA-dependent RNA Polymerase from Poliovirus (3Dpol)

J. Arnold, C. Cameron, A. Paul, 2002, The Journal of Biological Chemistry.

Interfering with nucleotide excision by the coronavirus 3′-to-5′ exoribonuclease

J. Arnold, C. Cameron, D. Dulin, 2022, Nucleic acids research.

Divalent cation modulation of the ribonuclease functions of human immunodeficiency virus reverse transcriptase.

C. Cameron, S. Benkovic, S. L. Le Grice, 1995, Biochemistry.

Effects of introduction of hydrophobic group on ribavirin base on mutation induction and anti-RNA viral activity.

C. Cameron, Masahiko Watanabe, Tetsuya Suzuki, 2008, Journal of medicinal chemistry.

Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer

L. Chodosh, J. Arnold, C. Cameron, 2016, Oncotarget.

Mechanisms of action of ribavirin against distinct viruses

C. Cameron, Jason D Graci, 2005, Reviews in medical virology.

Nucleic acid polymerases employ a general acid for nucleotidyl transfer

J. Arnold, C. Cameron, E. Smidansky, 2008, Nature Structural &Molecular Biology.

Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerases

J. Arnold, C. Cameron, E. Smidansky, 2007, Proceedings of the National Academy of Sciences.

Human mitochondrial RNA polymerase: structure-function, mechanism and inhibition.

J. Arnold, C. Cameron, E. Smidansky, 2012, Biochimica et biophysica acta.

Poliovirus RNA-dependent RNA polymerase (3Dpol): pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mg2+.

J. Arnold, C. Cameron, 2004, Biochemistry.

Poliovirus RNA-dependent RNA polymerase (3Dpol): kinetic, thermodynamic, and structural analysis of ribonucleotide selection.

J. Arnold, C. Cameron, D. Gohara, 2004, Biochemistry.

Poliovirus RNA-dependent RNA polymerase (3Dpol): pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mn2+.

J. Arnold, C. Cameron, D. Gohara, 2004, Biochemistry.

Dynamics: the missing link between structure and function of the viral RNA-dependent RNA polymerase?

J. Arnold, C. Cameron, I. Moustafa, 2009, Current Opinion in Structural Biology.

The nucleotide addition cycle of the SARS-CoV-2 polymerase

J. Arnold, C. Cameron, M. Depken, 2021, Cell Reports.

The nucleotide addition cycle of the SARS-CoV-2 polymerase

J. Arnold, C. Cameron, M. Depken, 2021, bioRxiv.

Triphosphate Reorientation of the Incoming Nucleotide as a Fidelity Checkpoint in Viral RNA-dependent RNA Polymerases*

J. Arnold, C. Cameron, Xiaorong Yang, 2017, The Journal of Biological Chemistry.

Fidelity of Nucleotide Incorporation by the RNA-Dependent RNA Polymerase from Poliovirus.

J. Arnold, C. Cameron, I. Moustafa, 2016, The Enzymes.

Vaccine-derived Mutation in Motif D of Poliovirus RNA-dependent RNA Polymerase Lowers Nucleotide Incorporation Fidelity*

J. Arnold, C. Cameron, E. Smidansky, 2013, The Journal of Biological Chemistry.

Motif D of viral RNA-dependent RNA polymerases determines efficiency and fidelity of nucleotide addition.

J. Arnold, C. Cameron, E. Smidansky, 2012, Structure.

Nucleic Acid Polymerase Fidelity and Viral Population Fitness

J. Arnold, C. Cameron, E. Smidansky, 2008 .

Structure-function relationships among RNA-dependent RNA polymerases.

J. Arnold, C. Cameron, K. Ng, 2008, Current topics in microbiology and immunology.

Remote Site Control of an Active Site Fidelity Checkpoint in a Viral RNA-dependent RNA Polymerase*

M. Vignuzzi, J. Stone, J. Arnold, 2005, Journal of Biological Chemistry.

Human mitochondrial RNA polymerase: evaluation of the single-nucleotide-addition cycle on synthetic RNA/DNA scaffolds.

J. Arnold, C. Cameron, E. Smidansky, 2011, Biochemistry.

A naturally occurring antiviral ribonucleotide encoded by the human genome

J. Arnold, C. Cameron, S. Almo, 2018, Nature.

Expanding the Proteome of an RNA Virus by Phosphorylation of an Intrinsically Disordered Viral Protein*

G. Ning, J. Arnold, C. Cameron, 2014, The Journal of Biological Chemistry.

RNA virus error catastrophe: Direct molecular test by using ribavirin

C. Cameron, R. Andino, S. Crotty, 2001, Proceedings of the National Academy of Sciences of the United States of America.

The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

J. Arnold, C. Cameron, R. Andino, 2000, Nature Medicine.

Induced copy-back RNA synthesis as a novel therapeutic mechanism against RNA viruses

J. Arnold, C. Cameron, N. Dekker, 2020, bioRxiv.

Sequence-Specific Fidelity Alterations Associated with West Nile Virus Attenuation in Mosquitoes

J. Arnold, C. Cameron, L. Kramer, 2015, PLoS pathogens.

A Chemical Strategy for Intracellular Arming of an Endogenous Broad-Spectrum Antiviral Nucleotide.

J. Arnold, C. Cameron, S. Sturla, 2021, Journal of medicinal chemistry.

Ribavirin's antiviral mechanism of action: lethal mutagenesis?

C. Cameron, R. Andino, S. Crotty, 2002, Journal of Molecular Medicine.

Pleiotropic mechanisms of ribavirin antiviral activities.

C. Cameron, Z. Hong, 2002, Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques.

[13] Purification and characterization of human immunodeficiency virus type 1 reverse transcriptase

C. Cameron, S. Benkovic, S. F. Grice, 1995 .

Determinants of RNA-Dependent RNA Polymerase (In)fidelity Revealed by Kinetic Analysis of the Polymerase Encoded by a Foot-and-Mouth Disease Virus Mutant with Reduced Sensitivity to Ribavirin

Armando Arias, J. Arnold, C. Cameron, 2008, Journal of Virology.

Picornavirus Genome Replication

J. Arnold, C. Cameron, I. Goodfellow, 2008, Journal of Biological Chemistry.

BIOCHEMICAL CHARACTERIZATION OF DENGUE NON-STRUCTURAL PROTEIN 5 ( NS 5 ) AND GENERAL ACID DERIVATIVES

C. Cameron, P. Berg, L. Parent, 2011 .

Template/Primer Requirements and Single Nucleotide Incorporation by Hepatitis C Virus Nonstructural Protein 5B Polymerase

C. Cameron, Z. Hong, W. Zhong, 2000, Journal of Virology.

Lethal Mutagenesis of Picornaviruses with N-6-Modified Purine Nucleoside Analogues

Blake R. Peterson, J. Martin Bollinger, David Loakes, 2008, Antimicrobial Agents and Chemotherapy.

Quasispecies, error catastrophe, and the antiviral activity of ribavirin.

C. Cameron, Jason D Graci, Craig E Cameron, 2002, Virology.

Truncating α-Helix E′ of p66 Human Immunodeficiency Virus Reverse Transcriptase Modulates RNase H Function and Impairs DNA Strand Transfer (*)

C. Cameron, S. Benkovic, S. Hughes, 1995, The Journal of Biological Chemistry.

Manganese-Dependent Polioviruses Caused by Mutations within the Viral Polymerase

C. Cameron, R. Andino, S. Crotty, 2003, Journal of Virology.

Poliovirus RNA-dependent RNA polymerase (3D(pol)). Divalent cation modulation of primer, template, and nucleotide selection.

J. Arnold, C. Cameron, S. Ghosh, 1999, The Journal of biological chemistry.

Correlation between NS5A Dimerization and Hepatitis C Virus Replication*

C. Cameron, P. Gallay, Suresh D. Sharma, 2012, The Journal of Biological Chemistry.

Inhibition of SARS-CoV-2 polymerase by nucleotide analogs: a single molecule perspective

J. Arnold, C. Cameron, S. Almo, 2020, bioRxiv.

Poliovirus RNA-Dependent RNA Polymerase (3Dpol): Structure, Function, and Mechanism

J. Arnold, C. Cameron, D. Gohara, 2002 .

Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53.

J. Arnold, C. Cameron, L. Linares, 2018, Molecular cell.

Native Tertiary Structure and Nucleoside Modifications Suppress tRNA’s Intrinsic Ability to Activate the Innate Immune Sensor PKR

C. Cameron, P. Bevilacqua, Saikat Ghosh, 2013, PloS one.

Robust genome and RNA editing via CRISPR nucleases in PiggyBac systems

C. Cameron, Yun Chao Chang, Xiaoping Bao, 2022, Bioactive materials.

A speed–fidelity trade-off determines the mutation rate and virulence of an RNA virus

J. Arnold, C. Cameron, R. Woods, 2018, bioRxiv.

A speed-fidelity trade-off determines the mutation rate and virulence of an RNA virus

J. Arnold, C. Cameron, R. Woods, 2018, bioRxiv.

Regulation of PKR by HCV IRES RNA: importance of domain II and NS5A.

C. Cameron, P. Bevilacqua, J. Boyer, 2010, Journal of molecular biology.

Melting of Duplex DNA in the Absence of ATP by the NS3 Helicase Domain through Specific Interaction with a Single-Strand/Double-Strand Junction.

Kimberly A. Reynolds, C. Cameron, K. Raney, 2015, Biochemistry.

Hepatitis C Virus Non-structural Protein 3 (HCV NS3): A Multifunctional Antiviral Target*

C. Cameron, K. Raney, Suresh D. Sharma, 2010, The Journal of Biological Chemistry.

Investigation of translocation, DNA unwinding, and protein displacement by NS3h, the helicase domain from the hepatitis C virus helicase.

C. Cameron, K. Raney, C. J. Fischer, 2010, Biochemistry.

NS3 Helicase from the Hepatitis C Virus Can Function as a Monomer or Oligomer Depending on Enzyme and Substrate Concentrations*

C. Cameron, A. Tackett, K. Raney, 2009, Journal of Biological Chemistry.

Hepatitis C Virus NS3 Helicase Forms Oligomeric Structures That Exhibit Optimal DNA Unwinding Activity in Vitro*

Cheryl F. Lichti, J. B. Jordan, C. Cameron, 2008, Journal of Biological Chemistry.

Structural and Biological Identification of Residues on the Surface of NS3 Helicase Required for Optimal Replication of the Hepatitis C Virus*

Kevin D Raney, Samuel G Mackintosh, J. B. Jordan, 2006, Journal of Biological Chemistry.

Multiple Full-length NS3 Molecules Are Required for Optimal Unwinding of Oligonucleotide DNA in Vitro*

C. Cameron, A. Tackett, K. Raney, 2005, Journal of Biological Chemistry.

Unwinding of nucleic acids by HCV NS3 helicase is sensitive to the structure of the duplex.

C. Cameron, A. Tackett, K. Raney, 2001, Nucleic acids research.

Binding by the hepatitis C virus NS3 helicase partially melts duplex DNA.

Kimberly A. Reynolds, C. Cameron, K. Raney, 2012, Biochemistry.

Insight into Poliovirus Genome Replication and Encapsidation Obtained from Studies of 3B-3C Cleavage Site Mutants

J. Arnold, C. Cameron, I. Goodfellow, 2009, Journal of Virology.

A range of catalytic efficiencies with avian retroviral protease subunits genetically linked to form single polypeptide chains.

C. Cameron, I. Weber, A. Skalka, 1991, The Journal of biological chemistry.

Single-Cell Virology: On-Chip Investigation of Viral Infection Dynamics.

C. Wilke, J. Arnold, C. Cameron, 2017, Cell reports.

Standing surface acoustic wave (SSAW)-based cell washing.

Peng Li, Nitesh Nama, Tony Jun Huang, 2015, Lab on a chip.

Standing Surface Acoustic Wave Based Cell Coculture

Tony Jun Huang, Xiaoyun Ding, Feng Guo, 2014, Analytical chemistry.

Characterization and mutational studies of equine infectious anemia virus dUTPase.

C. Cameron, F. Fuller, S. Payne, 1997, Biochimica et biophysica acta.

Poliovirus RNA-dependent RNA Polymerase (3Dpol) Is Sufficient for Template Switchingin Vitro *

J. Arnold, C. Cameron, 1999, The Journal of Biological Chemistry.

The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family

J. Arnold, C. Cameron, C. Lacroix, 2015, PLoS pathogens.

Picornavirus Genome Replication IDENTIFICATION OF THE SURFACE OF THE POLIOVIRUS (PV) 3C DIMER THAT INTERACTS WITH PV 3Dpol DURING VPg URIDYLYLATION AND CONSTRUCTION OF A STRUCTURAL MODEL FOR THE PV 3C 2 -3Dpol COMPLEX *

J. Arnold, C. Cameron, Z. Reitman, 2007 .

Discovery of Enterovirus A71-like nonstructural genomes in recent circulating viruses of the Enterovirus A species

C. Cameron, N. Dekker, S. Shih, 2018, Emerging Microbes & Infections.

Hepatitis C Virus Nonstructural Protein 5A (NS5A) Is an RNA-binding Protein*

J. Arnold, C. Cameron, M. R. Hargittai, 2005, Journal of Biological Chemistry.

Norovirus Proteinase-Polymerase and Polymerase Are Both Active Forms of RNA-Dependent RNA Polymerase

J. Arnold, C. Cameron, G. Belliot, 2005, Journal of Virology.

Expanding knowledge of P3 proteins in the poliovirus lifecycle.

C. Cameron, H. Oh, I. Moustafa, 2010, Future microbiology.

Identification of the oriI-Binding Site of Poliovirus 3C Protein by Nuclear Magnetic Resonance Spectroscopy

J. Arnold, C. Cameron, M. Foster, 2008, Journal of Virology.

Mutagen resistance and mutation restriction of St. Louis encephalitis virus.

C. Cameron, L. Kramer, A. Ciota, 2017, The Journal of general virology.

Biochemical and genetic analysis of the role of the viral polymerase in enterovirus recombination

J. Arnold, C. Cameron, David J. Evans, 2016, Nucleic acids research.

Lethal Mutagenesis of Picornaviruses with N-6-Modiﬁed Purine Nucleoside Analogues (cid:1) †

C. Cameron, J. Bollinger, E. Smidansky, 2008 .

Incorporation fidelity of the viral RNA-dependent RNA polymerase: a kinetic, thermodynamic and structural perspective☆

J. Arnold, C. Cameron, C. Castro, 2004, Virus Research.

Predicting Intraserotypic Recombination in Enterovirus 71

C. Cameron, N. Dekker, S. Shih, 2018, Journal of Virology.

Genetic recombination of poliovirus facilitates subversion of host barriers to infection

J. Arnold, C. Cameron, R. Andino, 2018, bioRxiv.

A Polymerase Mechanism-based Strategy for Viral Attenuation and Vaccine Development*

J. Arnold, C. Cameron, E. Smidansky, 2012, The Journal of Biological Chemistry.

The mechanism of action of ribavirin: lethal mutagenesis of RNA virus genomes mediated by the viral RNA-dependent RNA polymerase

C. Cameron, C. Castro, Christian Castro, 2001, Current opinion in infectious diseases.

Therapeutically targeting RNA viruses via lethal mutagenesis.

C. Cameron, Jason D Graci, Craig E Cameron, 2008, Future virology.

Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication

C. Cameron, T. Balla, N. Altan-Bonnet, 2010, Cell.

Complete nucleotide sequence of Kashmir bee virus and comparison with acute bee paralysis virus.

C. Cameron, M. Drebot, S. Camazine, 2004, The Journal of general virology.

Intermolecular Interactions within the Abundant DEAD-box Protein Dhh1 Regulate Its Activity in Vivo*

C. Cameron, D. Jain, J. Reese, 2011, The Journal of Biological Chemistry.

Modeling poliovirus replication dynamics from live time-lapse single-cell imaging data

Ashley I. Teufel, C. Wilke, J. Draghi, 2021, Scientific Reports.

5'-Triphosphate-Dependent Activation of PKR by RNAs with Short Stem-Loops

C. Cameron, P. Bevilacqua, Xiaofeng Zheng, 2007, Science.

The hepatitis C viral nonstructural protein 5A stabilizes growth-regulatory human transcripts

C. Cameron, P. Bohjanen, Suresh D. Sharma, 2018, Nucleic acids research.

The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent

J. Arnold, C. Cameron, E. Snijder, 2009, Nucleic acids research.

Poliovirus RNA-dependent RNA Polymerase (3Dpol)

J. Arnold, C. Cameron, R. Andino, 2000, The Journal of Biological Chemistry.

Poliovirus RNA-dependent RNA polymerase (3D(pol)). Assembly of stable, elongation-competent complexes by using a symmetrical primer-template substrate (sym/sub).

J. Arnold, C. Cameron, 2000, The Journal of biological chemistry.

Long-Range Communication between Different Functional Sites in the Picornaviral 3C Protein.

J. Arnold, C. Cameron, David D. Boehr, 2016, Structure.

Senecavirus-Specific Recombination Assays Reveal the Intimate Link between Polymerase Fidelity and RNA Recombination

C. Cameron, Decheng Yang, Li Yu, 2019, Journal of Virology.

HIV fusion: Catch me if you can

C. Cameron, 2020 .

Acoustofluidic bacteria separation

Xiangqun Zeng, Tony Jun Huang, Sixing Li, 2017, Journal of micromechanics and microengineering : structures, devices, and systems.

Acoustofluidic Transfer of Inflammatory Cells from Human Sputum Samples.

Po-Hsun Huang, Tony Jun Huang, Sixing Li, 2016, Analytical chemistry.

Structural Dynamics as a Contributor to Error-prone Replication by an RNA-dependent RNA Polymerase*

Janna K. Maranas, J. Arnold, C. Cameron, 2014, The Journal of Biological Chemistry.

Exploring the dynamics of four RNA-dependent RNA polymerases by a coarse-grained model.

C. Cameron, C. Colina, Hujun Shen, 2012, The journal of physical chemistry. B.

Molecular Dynamics Simulations of Viral RNA Polymerases Link Conserved and Correlated Motions of Functional Elements to Fidelity

Coray M. Colina, C. Cameron, Hujun Shen, 2011, Journal of Molecular Biology.

Kinetic analysis of nucleotide incorporation and misincorporation by Klenow fragment of Escherichia coli DNA polymerase I.

C. Cameron, S. Benkovic, 1995, Methods in enzymology.

RNA-Dependent RNA Polymerase Speed and Fidelity are not the Only Determinants of the Mechanism or Efficiency of Recombination

J. Arnold, C. Cameron, Hyejeong Kim, 2019, bioRxiv.

Mutations in HIV reverse transcriptase which alter RNase H activity and decrease strand transfer efficiency are suppressed by HIV nucleocapsid protein.

C. Cameron, S. Benkovic, S. L. Le Grice, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Structure, Dynamics, and Fidelity of RNA-Dependent RNA Polymerases

J. Arnold, C. Cameron, David D. Boehr, 2014 .

Hepatitis C virus NS3 and simian virus 40 T antigen helicases displace streptavidin from 5'-biotinylated oligonucleotides but not from 3'-biotinylated oligonucleotides: evidence for directional bias in translocation on single-stranded DNA.

Alicia K Byrd, Alan J Tackett, Ellen Fanning, 2002, Biochemistry.

Transcription from the second heavy-strand promoter of human mtDNA is repressed by transcription factor A in vitro

J. Arnold, C. Cameron, G. Shadel, 2012, Proceedings of the National Academy of Sciences.

Core human mitochondrial transcription apparatus is a regulated two-component system in vitro

C. Cameron, G. Shadel, M. F. Lodeiro, 2010, Proceedings of the National Academy of Sciences.

Expression and Purification of Mitochondrial RNA Polymerase and Transcription Factor A from Drosophila melanogaster.

J. Arnold, C. Cameron, T. Salminen, 2016, Methods in molecular biology.

Identification of Multiple Rate-limiting Steps during the Human Mitochondrial Transcription Cycle in Vitro*

J. Arnold, C. Cameron, M. F. Lodeiro, 2010, The Journal of Biological Chemistry.

Kinetic Analysis of Human PrimPol DNA Polymerase Activity Reveals a Generally Error-Prone Enzyme Capable of Accurately Bypassing 7,8-Dihydro-8-oxo-2′-deoxyguanosine

C. Cameron, M. F. Lodeiro, Amit D Ketkar, 2014, Biochemistry.

Measuring prenatal drug exposure.

C. Cameron, A. V. Patel, C. Bergin, 2001, Journal of pediatric nursing.

Picornavirus Genome Replication

J. Arnold, C. Cameron, Z. Reitman, 2008, Journal of Biological Chemistry.

Picornavirus Genome Replication

J. Arnold, C. Cameron, M. R. Hargittai, 2007, Journal of Biological Chemistry.

Hepatitis C Virus Nonstructural Protein 5A: Biochemical Characterization of a Novel Structural Class of RNA-Binding Proteins

C. Cameron, C. Kao, K. Raney, 2010, Journal of Virology.

Accurate nanoscale flexibility measurement of DNA and DNA–protein complexes by atomic force microscopy in liquid

C. Cameron, Divakaran Murugesapillai, Mark C. Williams, 2017, Nanoscale.

Temperature controlled high-throughput magnetic tweezers show striking difference in activation energies of replicating viral RNA-dependent RNA polymerases

J. Arnold, C. Cameron, M. Depken, 2020, bioRxiv.

Structural and functional characterization of the coxsackievirus B3 CRE(2C): role of CRE(2C) in negative- and positive-strand RNA synthesis.

C. Cameron, R. Andino, A. Paul, 2006, The Journal of general virology.

UGGT1 enhances enterovirus 71 pathogenicity by promoting viral RNA synthesis and viral replication

J. Arnold, C. Cameron, Jen-Ren Wang, 2017, PLoS pathogens.

Characterization of Protein-Phospholipid/Membrane Interactions Using a "Membrane-on-a-Chip" Microfluidic System.

C. Cameron, P. Cremer, Djoshkun Shengjuler, 2021, Methods in molecular biology.

Signatures of Nucleotide Analog Incorporation by an RNA-Dependent RNA Polymerase Revealed Using High-Throughput Magnetic Tweezers

J. Arnold, C. Cameron, T. van Laar, 2017, Cell Reports.

Isolation of Enzymatically Active Replication Complexes from Feline Calicivirus-Infected Cells

C. Cameron, G. Belliot, A. Weisberg, 2002, Journal of Virology.

The RNA-Binding Site of Poliovirus 3C Protein Doubles as a Phosphoinositide-Binding Domain

C. Cameron, M. Buck, P. Cremer, 2017, bioRxiv.

RNA Virus Population Diversity, an Optimum for Maximal Fitness and Virulence*

M. Vignuzzi, J. Arnold, C. Cameron, 2014, The Journal of Biological Chemistry.

Polymerase Fidelity Contributes to Foot-and-Mouth Disease Virus Pathogenicity and Transmissibility In Vivo

C. Cameron, Decheng Yang, Li Yu, 2020, Journal of Virology.

Foot-and-mouth disease virus type O specific mutations determine RNA-dependent RNA polymerase fidelity and virus attenuation.

C. Cameron, Decheng Yang, Li Yu, 2018, Virology.

Phosphate release contributes to the rate-limiting step for unwinding by an RNA helicase

J. Arnold, C. Cameron, K. Raney, 2009, Nucleic acids research.

Mutations that alter the activity of the Rous sarcoma virus protease.

A Wlodawer, C. Cameron, A. Wlodawer, 1992, The Journal of biological chemistry.

RNA unwinding activity of the hepatitis C virus NS3 helicase is modulated by the NS5B polymerase.

C. Cameron, K. Raney, E. Jankowsky, 2008, Biochemistry.

Electrochemically Created Highly Surface Roughened Ag Nanoplate Arrays for SERS Biosensing Applications.

C. Cameron, Shikuan Yang, Yanhui Zhao, 2014, Journal of materials chemistry. C.

Comparison of the substrate-binding pockets of the Rous sarcoma virus and human immunodeficiency virus type 1 proteases.

A Wlodawer, C. Cameron, A. Wlodawer, 1993, The Journal of biological chemistry.

Picornavirus Genome Replication ROLESOFPRECURSORPROTEINSANDRATE-LIMITINGSTEPSINoriI-DEPENDENT VPgURIDYLYLATION *

J. Arnold, C. Cameron, I. Goodfellow, 2008 .

Crystal Structure of Poliovirus 3CD Protein: Virally Encoded Protease and Precursor to the RNA-Dependent RNA Polymerase

J. Arnold, C. Cameron, D. Filman, 2007, Journal of Virology.

More than efficacy revealed by single-cell analysis of antiviral therapeutics

C. Wilke, J. Arnold, C. Cameron, 2019, Science Advances.

Signatures of Nucleotide A nalog Incorporation by an RNA-Dependent RNA Polymerase Revealed Using High-Throughput Magnetic Tweezers Graphical

J. Arnold, C. Cameron, M. Depken, 2017 .

Lethal mutagens: broad-spectrum antivirals with limited potential for development of resistance?

C. Cameron, M. Freistadt, G. Meades, 2004, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Rational control of poliovirus RNA-dependent RNA polymerase fidelity by modulating motif D loop conformational dynamics.

J. Arnold, C. Cameron, Xiaorong Yang, 2019, Biochemistry.

Purification and characterization of hepatitis C virus non-structural protein 5A expressed in Escherichia coli.

C. Cameron, M. R. Hargittai, K. Raney, 2004, Protein expression and purification.

and Hepatitis C Virus Replication Correlation between NS5A Dimerization RNA

C. Cameron, P. Gallay, Suresh D. Sharma, 2014 .

Analysis of substrate interactions of the Rous sarcoma virus wild type and mutant proteases and human immunodeficiency virus-1 protease using a set of systematically altered peptide substrates.

A Wlodawer, C. Cameron, A. Wlodawer, 1992, The Journal of biological chemistry.

Structure-Function Analysis of Vaccinia Virus H7 Protein Reveals a Novel Phosphoinositide Binding Fold Essential for Poxvirus Replication

C. Cameron, Junpeng Deng, Y. Xiang, 2014, Journal of Virology.

Maintenance of a host-specific minority mutation in the West Nile virus NS3

J. Arnold, C. Cameron, C. A. Koetzner, 2023, iScience.

Hepatitis C Virus Nonstructural Protein 5A (NS5A) Is an RNA-binding Protein*

J. Arnold, C. Cameron, M. R. Hargittai, 2005, Journal of Biological Chemistry.

Predicting Intra- and Intertypic Recombination in Enterovirus 71

C. Cameron, N. Dekker, S. Shih, 2018, bioRxiv.

Mutational Robustness of an RNA Virus Influences Sensitivity to Lethal Mutagenesis

M. Vignuzzi, C. Cameron, Jason D Graci, 2011, Journal of Virology.

Computational Analysis of Amiloride Analogue Inhibitors of Coxsackievirus B3 RNA Polymerase.

Steven Petrou, Michael W Parker, Bevyn Jarrott, 2014, Journal of proteomics & bioinformatics.

Polymerase Mechanism-Based Method of Viral Attenuation

J. Arnold, C. Cameron, A. August, 2015, Methods in molecular biology.

Correction: Moustafa, I.M.; et al. Conformational Ensemble of the Poliovirus 3CD Precursor Observed by MD Simulations and Confirmed by SAXS: A Strategy to Expand the Viral Proteome? Viruses 2015, 7, 5962–5986

C. Cameron, N. Yennawar, D. Gohara, 2015, Viruses.

Conformational Ensemble of the Poliovirus 3CD Precursor Observed by MD Simulations and Confirmed by SAXS: A Strategy to Expand the Viral Proteome?

C. Cameron, N. Yennawar, D. Gohara, 2015, Viruses.

Ribavirin's antiviral mechanism of action: lethal mutagenesis?

Uwe Hobohm, C. Cameron, R. Andino, 2002, Journal of Molecular Medicine.

Lethal Mutagenesis of Poliovirus Mediated by a Mutagenic Pyrimidine Analogue

Blake R. Peterson, David Loakes, C. Cameron, 2007, Journal of Virology.

Microfluidic opportunities in the field of nutrition.

C. Cameron, T. Huang, L. Sinoway, 2013, Lab on a chip.

Nucleobase but not Sugar Fidelity is Maintained in the Sabin I RNA-Dependent RNA Polymerase

J. Arnold, C. Cameron, Xiaorong Yang, 2015, Viruses.

Amiloride Is a Competitive Inhibitor of Coxsackievirus B3 RNA Polymerase

J. Arnold, C. Cameron, S. Petrou, 2011, Journal of Virology.

Abstract 1245: Enteroviral 2C protein is an RNA-stimulated ATPase and uses a two-step mechanism for binding to RNA and ATP

J. Arnold, C. Cameron, N. Yennawar, 2023, Journal of Biological Chemistry.

Unexpected sequences and structures of mtDNA required for efficient transcription from the first heavy-strand promoter

J. Arnold, C. Cameron, Divakaran Murugesapillai, 2017, bioRxiv.

Nucleic acid polymerases employ a general acid for nucleotidyl transfer

J. Arnold, C. Cameron, E. Smidansky, 2008, Nature Structural &Molecular Biology.

PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions.

C. Cameron, P. Cremer, Djoshkun Shengjuler, 2017, Journal of visualized experiments : JoVE.

Picornavirus Genome Replication

J. Arnold, C. Cameron, H. Pathak, 2008, Journal of Biological Chemistry.