E. Alnemri

发表

Recruitment, activation and retention of caspases‐9 and ‐3 by Apaf‐1 apoptosome and associated XIAP complexes

S. B. Bratton, G. Walker, S. Srinivasula, 2001, The EMBO journal.

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization.

S. Srinivasula, E. Alnemri, M. Ahmad, 1998, Molecular cell.

Serum Response Factor Cleavage by Caspases 3 and 7 Linked to Apoptosis in Human BJAB Cells*

N. Cheong, E. Alnemri, V. Drewett, 2001, The Journal of Biological Chemistry.

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

S. Srinivasula, E. Alnemri, Xiaodong Wang, 1997, Cell.

Cytochrome c and dATP-mediated Oligomerization of Apaf-1 Is a Prerequisite for Procaspase-9 Activation*

S. Srinivasula, E. Alnemri, R. Fishel, 1999, The Journal of Biological Chemistry.

CRADD, a novel human apoptotic adaptor molecule for caspase-2, and FasL/tumor necrosis factor receptor-interacting protein RIP.

S. Srinivasula, E. Alnemri, M. Ahmad, 1997, Cancer research.

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells.

S. Srinivasula, E. Alnemri, C. Croce, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Sensing Cytoplasmic Danger Signals by the Inflammasome

E. Alnemri, 2010, Journal of Clinical Immunology.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

S. Lipton, A. Ciechanover, T. Luedde, 2018, Cell Death & Differentiation.

Death effector domain-containing proteins DEDD and FLAME-3 form nuclear complexes with the TFIIIC102 subunit of human transcription factor IIIC

S. Srinivasula, E. Alnemri, T. Fernandes-Alnemri, 2002, Cell Death and Differentiation.

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

R A Knight, G Melino, D. Green, 2005, Cell Death and Differentiation.

Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation*

E. Alnemri, T. Fernandes-Alnemri, Christine A Juliana, 2012, The Journal of Biological Chemistry.

The ketone metabolite β-hydroxybutyrate blocks NLRP 3 inflammasome – mediated inflammatory disease

P. A. Crawford, E. Alnemri, T. Horvath, 2015 .

Non‐transcriptional regulation of NLRP3 inflammasome signaling by IL‐4

E. Alnemri, T. Fernandes-Alnemri, Inhwa Hwang, 2015, Immunology and cell biology.

Negative regulation of cytochrome c‐mediated oligomerization of Apaf‐1 and activation of procaspase‐9 by heat shock protein 90

S. Srinivasula, E. Alnemri, R. Weichselbaum, 2000, The EMBO journal.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

D Andrews, R A Knight, G Melino, 2014, Cell Death and Differentiation.

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

R A Knight, G Melino, S. Lipton, 2011, Cell Death and Differentiation.

Activation of the IκB Kinases by RIP via IKKγ/NEMO-mediated Oligomerization*

S. Srinivasula, E. Alnemri, T. Fernandes-Alnemri, 2000, The Journal of Biological Chemistry.

Activation of the Ikappa B kinases by RIP via IKKgamma /NEMO-mediated oligomerization.

S. Srinivasula, E. Alnemri, T. Fernandes-Alnemri, 2000, The Journal of biological chemistry.

Tristetraprolin regulates necroptosis during tonic Toll-like receptor 4 (TLR4) signaling in murine macrophages

E. Alnemri, D. Stumpo, P. Blackshear, 2020, The Journal of Biological Chemistry.

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

Emad S. Alnemri, Srinivasa M. Srinivasula, Yigong Shi, 2001, Nature.

Spodoptera frugiperda Caspase-1, a Novel Insect Death Protease That Cleaves the Nuclear Immunophilin FKBP46, Is the Target of the Baculovirus Antiapoptotic Protein p35*

S. Srinivasula, E. Alnemri, M. Ahmad, 1997, The Journal of Biological Chemistry.

An immunophilin is a component of the insect ecdysone receptor (EcR) complex.

L. Gilbert, E. Alnemri, Q. Song, 1997, Insect biochemistry and molecular biology.

Tim50, a Component of the Mitochondrial Translocator, Regulates Mitochondrial Integrity and Cell Death*

N. Cheong, E. Alnemri, Yun Deng, 2004, Journal of Biological Chemistry.

Expression and transcriptional regulation of caspase-14 in simple and complex epithelia

Y. Lazebnik, S. Srinivasula, E. Alnemri, 2002, Cell Death and Differentiation.

Isolation and assay of caspases.

S. Srinivasula, E. Alnemri, M. Ahmad, 2001, Methods in cell biology.

The Ced-3/Interleukin 1β Converting Enzyme-like Homolog Mch6 and the Lamin-cleaving Enzyme Mch2α Are Substrates for the Apoptotic Mediator CPP32*

S. Srinivasula, E. Alnemri, J. Trapani, 1996, The Journal of Biological Chemistry.

Processing of the Nedd2 precursor by ICE‐like proteases and granzyme B

E. Alnemri, J. Trapani, T. Fernandes-Alnemri, 1996, Genes to cells : devoted to molecular & cellular mechanisms.

Cloning and Expression of Four Novel Isoforms of Human Interleukin-1β Converting Enzyme with Different Apoptotic Activities (*)

E. Alnemri, T. Fernandes-Alnemri, G. Litwack, 1995, The Journal of Biological Chemistry.

Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor.

E. Alnemri, T. Burns, W. El-Deiry, 1999, Cancer research.

Control of erythroid cell production via caspase-mediated cleavage of transcription factor SCL/Tal-1

S. Srinivasula, E. Alnemri, G. Condorelli, 2003, Cell Death and Differentiation.

Heteronuclear Ribonucleoproteins C1 and C2, Components of the Spliceosome, Are Specific Targets of Interleukin 1β-converting Enzyme-like Proteases in Apoptosis*

E. Alnemri, G. Dreyfuss, M. Lavin, 1996, The Journal of Biological Chemistry.

Identification and characterization of murine caspase-14, a new member of the caspase family.

S. Srinivasula, E. Alnemri, M. Ahmad, 1998, Cancer research.

Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome*

E. Alnemri, E. Latz, T. Fernandes-Alnemri, 2010, The Journal of Biological Chemistry.

Ketone body β-hydroxybutyrate blocks the NLRP3 inflammasome-mediated inflammatory disease

P. A. Crawford, E. Alnemri, T. Horvath, 2015, Nature Medicine.

The NLR gene family: a standard nomenclature.

Lois J. Maltais, Emad S. Alnemri, Adam Godzik, 2008, Immunity.

Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3

D. Green, E. Alnemri, A. Oberst, 2015, Nature Communications.

Involvement of the AIM2, NLRC4, and NLRP3 Inflammasomes in Caspase-1 Activation by Listeria monocytogenes

E. Alnemri, T. Fernandes-Alnemri, Jianghong Wu, 2010, Journal of Clinical Immunology.

The AIM2 inflammasome is critical for innate immunity against Francisella tularensis

E. Alnemri, L. Eisenlohr, T. Fernandes-Alnemri, 2010, Nature Immunology.

Ribotoxic Stress through p38 Mitogen-activated Protein Kinase Activates in Vitro the Human Pyrin Inflammasome*

E. Alnemri, T. Fernandes-Alnemri, André B. Farias, 2013, The Journal of Biological Chemistry.

Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants.

E. Alnemri, T. Fernandes-Alnemri, Jianghong Wu, 2007, Molecular cell.

Overexpressed full-length human BCL2 extends the survival of baculovirus-infected Sf9 insect cells.

E. Alnemri, C. Croce, N. Robertson, 1992, Proceedings of the National Academy of Sciences of the United States of America.

The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity

S. Srinivasula, E. Alnemri, P. Vandenabeele, 2002, Cell Death and Differentiation.

In vitro activation of CPP 32 and Mch 3 by Mch 4 , a novel human apoptotic cysteine protease containing two FADD-like domains ( granzyme B / Mch 2 / protease cascade / FAS / APO-I-receptor )

E. Alnemri, F. Bullrich, T. Fernandes-Alnemri, 2005 .

A novel role for the mitochondrial HTRA2/OMI protease in aging

E. Alnemri, T. Fernandes-Alnemri, Seokwon Kang, 2013, Autophagy.

Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging

E. Alnemri, T. Fernandes-Alnemri, D. Strayer, 2012, Cell Death and Differentiation.

Inactivation of Omi/HtrA2 protease leads to the deregulation of mitochondrial Mulan E3 ubiquitin ligase and increased mitophagy.

E. Alnemri, D. Germain, A. Zervos, 2014, Biochimica et biophysica acta.

Nucleotides and Two Functional States of hsp90*

E. Alnemri, D. Toft, G. Litwack, 1997, The Journal of Biological Chemistry.

Caspase-mediated Cleavage of the Ubiquitin-protein Ligase Nedd4 during Apoptosis*

E. Alnemri, K. Harvey, D. Watters, 1998, The Journal of Biological Chemistry.

Treatment of malignant glioma cells with the transfer of constitutively active caspase-6 using the human telomerase catalytic subunit (human telomerase reverse transcriptase) gene promoter.

S. Srinivasula, E. Alnemri, J. Shay, 2001, Cancer research.

Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1

S. Srinivasula, E. Alnemri, R. Maria, 1999, Nature.

Interaction of the baculovirus anti-apoptotic protein p35 with caspases. Specificity, kinetics, and characterization of the caspase/p35 complex.

E. Alnemri, G. Salvesen, K. Tomaselli, 1998, Biochemistry.

Baculovirus P35 inhibits the glucocorticoid-mediated pathway of cell death.

E. Alnemri, T. Fernandes-Alnemri, N. Robertson, 1997, Cancer research.

Cooperative action of Hsp70, Hsp90, and DnaJ proteins in protein renaturation.

E. Alnemri, B. Freeman, D. Toft, 1996, Biochemistry.

Inflammasome Activity Associates with NLRP3 and Regulates Its The Mitochondrial Antiviral Protein MAVS

E. Alnemri, T. Fernandes-Alnemri, Christine A Juliana, 2013 .

The Mitochondrial Antiviral Protein MAVS Associates with NLRP3 and Regulates Its Inflammasome Activity

E. Alnemri, T. Fernandes-Alnemri, Christine A Juliana, 2013, The Journal of Immunology.

Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis

E. Alnemri, T. Fernandes-Alnemri, V. Tybulewicz, 2021, Nature Communications.

The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila

E. Alnemri, M. Fujioka, J. B. Jaynes, 2008, Cell Death and Differentiation.

HtrA2 and Parkinson's disease: think PINK?

E. Alnemri, 2007, Nature Cell Biology.

The Polypeptide Chain-releasing Factor GSPT1/eRF3 Is Proteolytically Processed into an IAP-binding Protein*

N. Cheong, S. Srinivasula, E. Alnemri, 2003, Journal of Biological Chemistry.

Calpain activation is upstream of caspases in radiation-induced apoptosis

D. Green, E. Alnemri, K. Khanna, 1998, Cell Death and Differentiation.

Multiple Autonomous Cell Death Suppression Strategies Ensure Cytomegalovirus Fitness

D. Green, E. Alnemri, C. Dillon, 2021, Viruses.

Mutant BRAF and MEK inhibitors regulate the tumor immune microenvironment via pyroptosis.

E. Alnemri, U. Rodeck, A. Aplin, 2019, Cancer discovery.

The Baculovirus Anti-apoptotic p35 Protein Promotes Transformation of Mouse Embryo Fibroblasts*

E. Alnemri, R. Baserga, M. Resnicoff, 1998, The Journal of Biological Chemistry.

Inhibition of ICE-related proteases (caspases) and nuclear apoptosis by phenylarsine oxide.

E. Alnemri, W. Earnshaw, K. Nakajima, 1997, Experimental cell research.

Granzyme B/perforin-mediated apoptosis of Jurkat cells results in cleavage of poly(ADP-ribose) polymerase to the 89-kDa apoptotic fragment and less abundant 64-kDa fragment.

E. Alnemri, G. Salvesen, W. Earnshaw, 1996, Biochemical and biophysical research communications.

Purification of the death substrate poly(ADP-ribose) polymerase.

E. Alnemri, W. Earnshaw, V. Dixit, 1997, Analytical biochemistry.

Regulation of IL-1β generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins

S. Srinivasula, E. Alnemri, M. Razmara, 2001, Cell Death and Differentiation.

Mammalian cell death proteases: A family of highly conserved aspartate specific cysteine proteases

E. Alnemri, 1997, Journal of cellular biochemistry.

Identification and Molecular Cloning of Two Novel Receptors for the Cytotoxic Ligand TRAIL*

S. Srinivasula, E. Alnemri, G. Cohen, 1997, The Journal of Biological Chemistry.

Critical Roles of ASC Inflammasomes in Caspase-1 Activation and Host Innate Resistance to Streptococcus pneumoniae Infection

E. Alnemri, T. Fernandes-Alnemri, I. Kawamura, 2011, The Journal of Immunology.

Infection Streptococcus pneumoniae Resistance to Caspase-1 Activation and Host Innate Critical Roles of ASC Inflammasomes in

E. Alnemri, T. Fernandes-Alnemri, I. Kawamura, 2011 .

Cascades of Mammalian Caspase Activation in the YeastSaccharomyces cerevisiae *

S. Srinivasula, E. Alnemri, M. Bjornsti, 1999, The Journal of Biological Chemistry.

Overexpression and characterization of the human mineralocorticoid receptor.

A. B. Maksymowych, E. Alnemri, N. Robertson, 1991, The Journal of biological chemistry.

FLIP is expressed in mouse testis and protects germ cells from apoptosis

S. Srinivasula, E. Alnemri, S. Petrungaro, 2003, Cell Death and Differentiation.

CARD-8 Protein, a New CARD Family Member That Regulates Caspase-1 Activation and Apoptosis*

J. Bertin, P. Distefano, S. Srinivasula, 2002, The Journal of Biological Chemistry.

SUMO-mediated regulation of NLRP3 modulates inflammasome activity

E. Alnemri, T. Fernandes-Alnemri, T. Tenev, 2018, Nature Communications.

This information is current as Signaling and Proteasome Function Lipopolysaccharide Is Dependent upon ERK Inflammasome Priming by Alnemri

E. Alnemri, T. Fernandes-Alnemri, M. Wewers, 2014 .

Assembly, purification, and assay of the activity of the ASC pyroptosome.

E. Alnemri, T. Fernandes-Alnemri, T. Fernandes‐Alnemri, 2008, Methods in enzymology.

The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation

E. Alnemri, J. Mecsas, Peter F. Johnson, 2016, PLoS pathogens.

Identification of an endogenous dominant-negative short isoform of caspase-9 that can regulate apoptosis.

Y. Lazebnik, S. Srinivasula, E. Alnemri, 1999, Cancer research.

The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection

E. Alnemri, M. Chamaillard, Grace Y Chen, 2018, Cell.

Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.

E. Alnemri, T. Fernandes-Alnemri, J. Sagara, 2006, Cell death and differentiation.

New Member of the Caspase Family Identification and Characterization of Murine Caspase-14 , a Updated Version

Srinivasa, Manzoor, E. Alnemri, 2006 .

Identification and Characterization of Murine Caspase-14, a New Member of the Caspase Family1

Srinivasa, Manzoor, E. Alnemri, 2006 .

Resistance of actin to cleavage during apoptosis.

E. Alnemri, M. Lavin, S. Lees-Miller, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Activation of internucleosomal DNA cleavage in human CEM lymphocytes by glucocorticoid and novobiocin. Evidence for a non-Ca2(+)-requiring mechanism(s).

E. Alnemri, G. Litwack, 1990, The Journal of biological chemistry.

Translation termination factor eRF3 is targeted for caspase-mediated proteolytic cleavage and degradation during DNA damage-induced apoptosis

E. Alnemri, S. Hoshino, Y. Hashimoto, 2012, Apoptosis.

Caspase-Dependent Pathway Receptor Ligation Proceeds Via a Novel B Cell Apoptosis Triggered by Antigen

S. Srinivasula, E. Alnemri, N. Cooper, 1999 .

Activation of CPP32 and Mch3 alpha in wild-type p53-induced apoptosis.

E. Alnemri, G. Cohen, M. MacFarlane, 1997, The Biochemical journal.

Gene Promoter Catalytic Subunit ( Human Telomerase Reverse Transcriptase ) Constitutively Active Caspase-6 Using the Human Telomerase Treatment of Malignant Glioma Cells with the Transfer of Updated

S. Srinivasula, E. Alnemri, J. Shay, 2001 .

Interleukin-1 beta-converting enzyme-like protease cleaves DNA- dependent protein kinase in cytotoxic T cell killing

D. Chan, E. Alnemri, J. Trapani, 1996, The Journal of experimental medicine.

Phosphorylation of the insect immunophilin FKBP46 by the Spodoptera frugiperda homolog of casein kinase II.

E. Alnemri, S. Planey, N. Robertson, 2000, Gene.

Cutting Edge: TLR Signaling Licenses IRAK1 for Rapid Activation of the NLRP3 Inflammasome

E. Alnemri, T. Fernandes-Alnemri, K. Fitzgerald, 2013, The Journal of Immunology.

Role of Omi/HtrA2 in Apoptotic Cell Death After Myocardial Ischemia and Reperfusion

E. Alnemri, W. Koch, P. Most, 2005, Circulation.

Restoration of ASC expression sensitizes colorectal cancer cells to genotoxic stress-induced caspase-independent cell death.

E. Alnemri, T. Fernandes-Alnemri, You-Sun Kim, 2013, Cancer letters.

Advances in Brief Mch 3 , a Novel Human Apoptotic Cysteine Protease Highly Related to CPP 321

E. Alnemri, C. Croce, T. Fernandes-Alnemri, 2006 .

Advances in Brief Mch 2 , a New Member of the Apoptotic Ced-3 IIce Cysteine Protease Gene Family 1

E. Alnemri, T. Fernandes-Alnemri, G. Litwack, 2006 .

Cell-free synthesis of rat glucocorticoid receptor in rabbit reticulocyte lysate. In vitro synthesis of receptor in Mr 90,000 heat shock protein-depleted lysate.

A. B. Maksymowych, E. Alnemri, V. Daniel, 1991, The Journal of biological chemistry.

Control of apoptosis by using small molecule regulators of Bcl-2 family proteins

E. Alnemri, C. Croce, Ziwei Huang, 2002 .

Role of Smac in human leukaemic cell apoptosis and proliferation

S. Srinivasula, E. Alnemri, A. Newland, 2003, Oncogene.

Role of Omi / HtrA 2 in Apoptotic Cell Death After Myocardial Ischemia and Reperfusion

E. Alnemri, W. Koch, P. Most, 2004 .

Retro viral Transfer of CPP32ÃŸGene into Malignant Gliomas in Vitro and in Vivo1

Yasuko, E. Alnemri, G. Barnett, 2006 .

Retroviral Transfer of CPP32β Gene into Malignant Gliomas in Vitro and in Vivo

E. Alnemri, G. Barnett, Yoshikazu Tanaka, 1998 .

Translation termination factor eRF3 is targeted for caspase-mediated proteolytic cleavage and degradation during DNA damage-induced apoptosis

E. Alnemri, S. Hoshino, Y. Hashimoto, 2012, Apoptosis.

Omi/HtrA2 protease mediates cisplatin-induced cell death in renal cells.

E. Alnemri, A. Yerkes, K. Park, 2005, American journal of physiology. Renal physiology.

Regulation of HAX-1 Anti-apoptotic Protein by Omi/HtrA2 Protease during Cell Death*

E. Alnemri, Sanjeev Gupta, J. Bonventre, 2004, Journal of Biological Chemistry.

Triad3a induces the degradation of early necrosome to limit RipK1-dependent cytokine production and necroptosis

E. Alnemri, R. Korneluk, S. Sad, 2018, Cell Death & Disease.

Functional characterization of mitochondria in neutrophils: a role restricted to apoptosis

S. Srinivasula, E. Alnemri, T. Kuijpers, 2004, Cell Death and Differentiation.

Gasdermins: novel mitochondrial pore-forming proteins

E. Alnemri, Corey Rogers, 2019, Molecular & cellular oncology.

Characterization and purification of a functional rat glucocorticoid receptor overexpressed in a baculovirus system.

A. B. Maksymowych, E. Alnemri, N. Robertson, 1991, The Journal of biological chemistry.

Human ICE/CED-3 Protease Nomenclature

Junying Yuan, E. Alnemri, Junying Yuan, 1996, Cell.

Ordering the Cytochrome c–initiated Caspase Cascade: Hierarchical Activation of Caspases-2, -3, -6, -7, -8, and -10 in a Caspase-9–dependent Manner

Emad S. Alnemri, Seamus J. Martin, D. Green, 1999, The Journal of cell biology.

CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme.

E. Alnemri, T. Fernandes-Alnemri, G. Litwack, 1994, The Journal of biological chemistry.

Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression1

E. Alnemri, V. Hornung, B. Monks, 2009, The Journal of Immunology.

The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

E. Alnemri, T. Fernandes-Alnemri, Jianghong Wu, 2007, Cell Death and Differentiation.

CARD9 Is a Novel Caspase Recruitment Domain-containing Protein That Interacts With BCL10/CLAP and Activates NF-κB*

J. Bertin, P. Distefano, S. Srinivasula, 2000, The Journal of Biological Chemistry.

Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation

E. Alnemri, A. Aplin, T. Fernandes-Alnemri, 2019, Nature Communications.

Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death

E. Alnemri, T. Fernandes-Alnemri, G. Cingolani, 2017, Nature Communications.

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

R A Knight, G Melino, G M Cohen, 2009, Cell Death and Differentiation.

Identification of multiple glucocorticoid receptor binding sites in the rat osteocalcin gene promoter.

G. Stein, J. Lian, E. Alnemri, 1993, Biochemistry.

Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis.

J. Bertin, E. Alnemri, B. Moss, 1997, Proceedings of the National Academy of Sciences of the United States of America.

The steroid binding domain influences intracellular solubility of the baculovirus overexpressed glucocorticoid and mineralocorticoid receptors.

E. Alnemri, G. Litwack, 1993, Biochemistry.

Involvement of BCL-2 in glucocorticoid-induced apoptosis of human pre-B-leukemias.

E. Alnemri, C. Croce, S. Haldar, 1992, Cancer research.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

S. Lipton, A. Ciechanover, T. Luedde, 2018, Cell Death & Differentiation.

Apoptosis in human monocytic THP.1 cells involves several distinct targets of N-tosyl-L-phenylalanyl chloromethyl ketone (TPCK)

E. Alnemri, G. Cohen, D. Dinsdale, 1997, Cell Death and Differentiation.

Gasdermins in Apoptosis: New players in an Old Game

E. Alnemri, Corey Rogers, 2019, The Yale journal of biology and medicine.

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

E. Alnemri, T. Fernandes-Alnemri, Jianghong Wu, 2009, Nature.

B cell apoptosis triggered by antigen receptor ligation proceeds via a novel caspase-dependent pathway.

S. Srinivasula, E. Alnemri, H. G. Wang, 1999, Journal of immunology.

The mitochondrial protease HtrA2 restricts the NLRP3 and AIM2 inflammasomes

E. Alnemri, M. Saleh, S. Vidal, 2018, Scientific Reports.

IAPs block apoptotic events induced by caspase‐8 and cytochrome c by direct inhibition of distinct caspases

J C Reed, S. Srinivasula, E. Alnemri, 1998, The EMBO journal.

Negative regulation of the Apaf-1 apoptosome by Hsp70

Emad S. Alnemri, Srinivasa M. Srinivasula, S. Srinivasula, 2000, Nature Cell Biology.

Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms

S. Srinivasula, E. Alnemri, R. Hotchkiss, 2004, Nature.

Inflammasome Priming by Lipopolysaccharide Is Dependent upon ERK Signaling and Proteasome Function

E. Alnemri, T. Fernandes-Alnemri, M. Wewers, 2014, The Journal of Immunology.

Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice

S. Srinivasula, E. Alnemri, W. Ji, 2003, Nature.

THAP5 is a human cardiac-specific inhibitor of cell cycle that is cleaved by the proapoptotic Omi/HtrA2 protease during cell death.

E. Alnemri, A. Zervos, L. Cilenti, 2009, American journal of physiology. Heart and circulatory physiology.

FGF Induces a Switch in Death Receptor Pathways in Neuronal Cells

E. Alnemri, E. Eves, M. Rosner, 2001, The Journal of Neuroscience.

E1A-induced Processing of Procaspase-8 Can Occur Independently of FADD and Is Inhibited by Bcl-2*

E. Alnemri, T. Mak, P. Branton, 1998, The Journal of Biological Chemistry.

FLAME-1, a Novel FADD-like Anti-apoptotic Molecule That Regulates Fas/TNFR1-induced Apoptosis*

S. Srinivasula, E. Alnemri, C. Croce, 1997, The Journal of Biological Chemistry.

Processing/Activation of At Least Four Interleukin-1β Converting Enzyme–like Proteases Occurs during the Execution Phase of Apoptosis in Human Monocytic Tumor Cells

E. Alnemri, G. Cohen, M. MacFarlane, 1997, The Journal of cell biology.

Activation of the CED3/ICE-Related Protease CPP32 in Cerebellar Granule Neurons Undergoing Apoptosis But Not Necrosis

E. Alnemri, R. Armstrong, L. Fritz, 1997, The Journal of Neuroscience.

Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases.

S. Srinivasula, E. Alnemri, M. Ahmad, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family.

E. Alnemri, T. Fernandes-Alnemri, G. Litwack, 1995, Cancer research.

Caspase-2 Induces Apoptosis by Releasing Proapoptotic Proteins from Mitochondria*

S. Srinivasula, E. Alnemri, T. Fernandes-Alnemri, 2002, The Journal of Biological Chemistry.

Bax translocation is crucial for the sensitivity of leukaemic cells to etoposide-induced apoptosis

S. Srinivasula, E. Alnemri, T. Fernandes-Alnemri, 2001, Oncogene.

Apaf-1 protein deficiency confers resistance to cytochrome c-dependent apoptosis in human leukemic cells.

S. Srinivasula, E. Alnemri, L. Jia, 2001, Blood.

Synthetic peptide sequence from the C‐terminus of the insulin‐like growth factor‐I receptor that induces apoptosis and inhibition of tumor growth

S. Srinivasula, E. Alnemri, K. Reiss, 1999, Journal of cellular physiology.

CLAP, a Novel Caspase Recruitment Domain-containing Protein in the Tumor Necrosis Factor Receptor Pathway, Regulates NF-κB Activation and Apoptosis*

S. Srinivasula, E. Alnemri, T. Fernandes-Alnemri, 1999, The Journal of Biological Chemistry.

Abrogation of Mitochondrial Cytochrome c Release and Caspase-3 Activation in Acquired Multidrug Resistance*

E. Alnemri, B. Teicher, D. Kufe, 1998, The Journal of Biological Chemistry.

Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis.

Y. Lazebnik, E. Alnemri, W. Earnshaw, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.

S. Korsmeyer, S. Srinivasula, E. Alnemri, 2003, Cancer research.

Release Differential Regulation of Cytochrome c and Smac / DIABLO ( TRAIL )-induced Mitochondrial Disruption and Apoptosis : Tumor Necrosis Factor-related Apoptosis-inducing Ligand Involvement of Proapoptotic Molecules Bax and Bak in Updated

S. Korsmeyer, S. Srinivasula, E. Alnemri, 2003 .

Rapid Kinetics of tBid-induced Cytochrome c and Smac/DIABLO Release and Mitochondrial Depolarization*

György Hajnóczky, S. Srinivasula, E. Alnemri, 2002, The Journal of Biological Chemistry.

Temperature-sensitive Differential Affinity of TRAIL for Its Receptors

Emad S. Alnemri, Srinivasa M. Srinivasula, Michael L. Doyle, 2000, The Journal of Biological Chemistry.

Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi

Emad S. Alnemri, Srinivasa M. Srinivasula, Yigong Shi, 2002, Nature Structural Biology.

NF-κB Activation by Card Proteins

E. Alnemri, J. Poyet, 2003 .

CARD11 and CARD14 Are Novel Caspase Recruitment Domain (CARD)/Membrane-associated Guanylate Kinase (MAGUK) Family Members that Interact with BCL10 and Activate NF-κB*

Emad S. Alnemri, Jean-Luc Poyet, Srinivasa M. Srinivasula, 2001, The Journal of Biological Chemistry.

Natural Killer (NK) Cell–mediated Cytotoxicity: Differential Use of TRAIL and Fas Ligand by Immature and Mature Primary Human NK Cells

E. Alnemri, L. Azzoni, B. Perussia, 1998, The Journal of experimental medicine.

Blk, a BH3-containing Mouse Protein That Interacts with Bcl-2 and Bcl-xL, Is a Potent Death Agonist*

S. Srinivasula, E. Alnemri, T. Fernandes-Alnemri, 1998, The Journal of Biological Chemistry.

The C-terminal Tail of Presenilin Regulates Omi/HtrA2 Protease Activity*

S. Srinivasula, E. Alnemri, M. Meisler, 2004, Journal of Biological Chemistry.

Mechanism of XIAP-mediated inhibition of caspase-9.

S. Srinivasula, E. Alnemri, R. Fairman, 2003, Molecular cell.

vCLAP, a Caspase-recruitment Domain-containing Protein of Equine Herpesvirus-2, Persistently Activates the IκB Kinases through Oligomerization of IKKγ*

S. Srinivasula, E. Alnemri, J. Poyet, 2001, The Journal of Biological Chemistry.

Caspase Cleavage Enhances the Apoptosis-Inducing Effects of BAD

S. Srinivasula, E. Alnemri, B. Calabretta, 2001, Molecular and Cellular Biology.

Cryopyrin and pyrin activate caspase-1, but not NF-κB, via ASC oligomerization

E. Alnemri, T. Fernandes-Alnemri, Jianghong Wu, 2006, Cell Death and Differentiation.

CARD10 Is a Novel Caspase Recruitment Domain/Membrane-associated Guanylate Kinase Family Member That Interacts with BCL10 and Activates NF-κB*

Emad S. Alnemri, Jean-Luc Poyet, John Bertin, 2001, The Journal of Biological Chemistry.

Characterization of Caspase Processing and Activation in HL-60 Cell Cytosol Under Cell-free Conditions

J C Reed, S H Kaufmann, S. Srinivasula, 1999, The Journal of Biological Chemistry.

Activation of the CPP32 protease in apoptosis induced by 1-beta-D-arabinofuranosylcytosine and other DNA-damaging agents.

E. Alnemri, D. Kufe, R. Talanian, 1996, Blood.

Inhibitor of Apoptosis Proteins Are Substrates for the Mitochondrial Serine Protease Omi/HtrA2*

N. Cheong, S. Srinivasula, E. Alnemri, 2003, Journal of Biological Chemistry.

sickle, a Novel Drosophila Death Gene in the reaper/hid/grim Region, Encodes an IAP-Inhibitory Protein

S. Srinivasula, E. Alnemri, Yigong Shi, 2002, Current Biology.

Identification of Omi/HtrA2 as a Mitochondrial Apoptotic Serine Protease That Disrupts Inhibitor of Apoptosis Protein-Caspase Interaction*

Yuri Lazebnik, Y. Lazebnik, S. Srinivasula, 2002, The Journal of Biological Chemistry.

Structural Basis of Caspase-7 Inhibition by XIAP

S. Srinivasula, E. Alnemri, Yigong Shi, 2001, Cell.

Molecular Determinants of the Caspase-promoting Activity of Smac/DIABLO and Its Role in the Death Receptor Pathway*

S. Srinivasula, E. Alnemri, T. Fernandes-Alnemri, 2000, The Journal of Biological Chemistry.

In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains.

S. Srinivasula, E. Alnemri, J. Trapani, 1996, Proceedings of the National Academy of Sciences of the United States of America.

DNA‐dependent protein kinase catalytic subunit: a target for an ICE‐like protease in apoptosis.

D. Chan, E. Alnemri, K. Khanna, 1996, The EMBO journal.

X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility

E. Alnemri, U. Rapp, M. Hekman, 2008, Nature Cell Biology.

Cell permeable Bcl-2 binding peptides: a chemical approach to apoptosis induction in tumor cells.

E. Alnemri, C. Croce, Ziwei Huang, 2000, Cancer research.

Intrinsic Pathway for Apoptosis

E. Alnemri, 2004 .

correction: A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

Emad S. Alnemri, Srinivasa M. Srinivasula, Yigong Shi, 2001, Nature.

Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1

Emad S. Alnemri, Srinivasa M. Srinivasula, Geng Wu, 1999, Nature.

Amino acid sequences of stomach and nonstomach lysozymes of ruminants

E. Alnemri, A. Wilson, E. M. Prager, 1990, Journal of Molecular Evolution.

The PYRIN-CARD Protein ASC Is an Activating Adaptor for Caspase-1*

S. Srinivasula, E. Alnemri, M. Razmara, 2002, The Journal of Biological Chemistry.

Cleavage and activation of p21-activated protein kinase gamma-PAK by CPP32 (caspase 3). Effects of autophosphorylation on activity.

E. Alnemri, G. Litwack, Z. Huang, 1998, The Journal of biological chemistry.

Intramitochondrial serine protease activity of Omi/HtrA2 is required for caspase-independent cell death of human neutrophils

E. Alnemri, T. Kuijpers, A. Zervos, 2004, Cell Death and Differentiation.

E. Alnemri, P. Secchiero, M. Vitale, 2000, Blood.

Cleavage of Ia A by Mch 2 a but not CPP 32 : Multiple interleukin 113-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis

E. Alnemri, G. Poirier, T. Fernandes-Alnemri, 2005 .

Cutting Edge: Mutation of Francisella tularensis mviN Leads to Increased Macrophage Absent in Melanoma 2 Inflammasome Activation and a Loss of Virulence

E. Alnemri, D. Meyerholz, F. Sutterwala, 2010, The Journal of Immunology.

Virulence Inflammasome Activation and a Loss of Macrophage Absent in Melanoma 2 Leads to Increased tularensis mviN Francisella Cutting Edge : Mutation of Nauseef and

E. Alnemri, D. Meyerholz, F. Sutterwala, 2010 .

Identification of Ipaf, a Human Caspase-1-activating Protein Related to Apaf-1*

S. Srinivasula, E. Alnemri, M. Razmara, 2001, The Journal of Biological Chemistry.

Generation of Constitutively Active Recombinant Caspases-3 and -6 by Rearrangement of Their Subunits*

S. Srinivasula, E. Alnemri, T. Fernandes-Alnemri, 1998, The Journal of Biological Chemistry.

Retroviral transfer of CPP32beta gene into malignant gliomas in vitro and in vivo.

E. Alnemri, G. Barnett, Y. Kondo, 1998, Cancer research.

Tpl‐2 induces apoptosis by promoting the assembly of protein complexes that contain caspase‐9, the adapter protein Tvl‐1, and procaspase‐3

S. Srinivasula, E. Alnemri, P. Tsichlis, 2001, Journal of cellular physiology.

Mutations in NALP12 cause hereditary periodic fever syndromes

S. Marlin, E. Alnemri, T. Fernandes-Alnemri, 2008, Proceedings of the National Academy of Sciences.

Crystal Structure of a Procaspase-7 Zymogen Mechanisms of Activation and Substrate Binding

Emad S. Alnemri, Srinivasa M. Srinivasula, Yigong Shi, 2001, Cell.

Oligomerization Is a General Mechanism for the Activation of Apoptosis Initiator and Inflammatory Procaspases*

S. Srinivasula, E. Alnemri, Xiaolu Yang, 2003, The Journal of Biological Chemistry.

Human Leukemic Cell Line CEM C-7 Receptor and Inhibits Glucocorticoid-induced Apoptosis in the Modulator Inhibits Nuclear Translocation of the Glucocorticoid Updated Version

Gerald, E. Alnemri, P. Bodine, 2006 .

Modulator inhibits nuclear translocation of the glucocorticoid receptor and inhibits glucocorticoid-induced apoptosis in the human leukemic cell line CEM C-7.

E. Alnemri, P. Bodine, N. Robertson, 1995, Cancer research.

Characterization of a Novel and Specific Inhibitor for the Pro-apoptotic Protease Omi/HtrA2*

S. Srinivasula, E. Alnemri, K. Park, 2003, The Journal of Biological Chemistry.

Caspase-mediated Cleavage of DNA Topoisomerase I at Unconventional Sites during Apoptosis*

E. Alnemri, J. Champoux, F. Durrieu, 1999, The Journal of Biological Chemistry.

Hidden powers of the mitochondria

E. Alnemri, 1999, Nature Cell Biology.

FKBP46, a novel Sf9 insect cell nuclear immunophilin that forms a protein-kinase complex.

E. Alnemri, T. Fernandes-Alnemri, N. Robertson, 1994, The Journal of biological chemistry.

Activation of a CrmA-insensitive, p35-sensitive Pathway in Ionizing Radiation-induced Apoptosis*

Emad S. Alnemri, Ralph R. Weichselbaum, E. Alnemri, 1997, The Journal of Biological Chemistry.

Tumor necrosis factor alpha induces BID cleavage and bypasses antiapoptotic signals in prostate cancer LNCaP cells.

S. Srinivasula, E. Alnemri, G. Kulik, 2001, Cancer research.

c-IAP1 blocks TNFalpha-mediated cytotoxicity upstream of caspase-dependent and -independent mitochondrial events in human leukemic cells.

S. Srinivasula, E. Alnemri, A. Newland, 2001, Biochemical and biophysical research communications.

Apoptotic cell death in disease—Current understanding of the NCCD 2023

S. Lipton, A. Ciechanover, T. Luedde, 2023, Cell Death & Differentiation.

Functional consequences of a germline mutation in the leucine-rich repeat domain of NLRP3 identified in an atypical autoinflammatory disorder.

E. Alnemri, L. Cuisset, S. Amselem, 2010, Arthritis and rheumatism.

Demonstration of nuclear translocation of the mineralocorticoid receptor (MR) using an anti-MR antibody and confocal laser scanning microscopy.

E. Alnemri, N. Robertson, G. Litwack, 1993, Molecular endocrinology.

Glucocorticoid-induced lymphocytolysis is not mediated by an induced endonuclease.

E. Alnemri, G. Litwack, 1989, The Journal of biological chemistry.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

The unliganded mineralocorticoid receptor is associated with heat shock proteins 70 and 90 and the immunophilin FKBP-52.

E. Alnemri, T. Fernandes-Alnemri, N. Robertson, 1997, Receptors & signal transduction.

Overexpression, characterization, and purification of a recombinant mouse immunophilin FKBP-52 and identification of an associated phosphoprotein.

E. Alnemri, T. Fernandes-Alnemri, G. Litwack, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Caspase‐3 Expression by Cerebellar Granule Neurons Is Regulated by Calcium and Cyclic AMP

E. Alnemri, D. Pleasure, J. Morán, 1999, Journal of neurochemistry.

This information is current as Inflammasome Activity Associates with NLRP 3 and Regulates Its The Mitochondrial Antiviral Protein MAVS

E. Alnemri, Inhwa Hwang, Sujeong Hong, 2013 .

Mch3, a novel human apoptotic cysteine protease highly related to CPP32.

E. Alnemri, C. Croce, W. Earnshaw, 1995, Cancer research.

Advances in Brief CRADD , a Novel Human ApoptoticAdaptor Moleculefor Caspase-2 , and FasL / Tumor Necrosis Factor Receptor-interacting Protein RIP '

Gerald, Manzoor, E. Alnemri, 2006 .

Chromosomal mapping of cell death proteases CPP32, MCH2, and MCH3.

E. Alnemri, C. Croce, F. Bullrich, 1996, Genomics.

The mitochondrial protease HtrA2 restricts the NLRP3 and AIM2 inflammasomes

E. Alnemri, M. Saleh, S. Vidal, 2018, Scientific Reports.

The NLR gene family: a standard nomenclature.

A. Godzik, J. Bertin, E. Alnemri, 2008, Immunity.

Biochemical Dissection of Nuclear Events in Apoptosis

Y. Lazebnik, E. Alnemri, R. Goldman, 1997 .

SUMO-mediated regulation of NLRP3 modulates inflammasome activity

E. Alnemri, T. Tenev, P. Meier, 2018, Nature Communications.

This information is current as Signaling and Proteasome Function Lipopolysaccharide Is Dependent upon ERK Inflammasome Priming by Alnemri

E. Alnemri, M. Wewers, M. Gavrilin, 2014 .

This information is current as Inflammasome IRAK 1 for Rapid Activation of the NLRP 3 Cutting Edge : TLR Signaling Licenses

E. Alnemri, K. Fitzgerald, J. Sagara, 2013 .

Restoration of ASC expression sensitizes colorectal cancer cells to genotoxic stress-induced caspase-independent cell death.

E. Alnemri, You-Sun Kim, Inhwa Hwang, 2013, Cancer letters.

Cleavage and Activation of p21-activated Protein Kinase γ-PAK by CPP32 (Caspase 3)

E. Alnemri, G. Litwack, B. Walter, 1998, The Journal of Biological Chemistry.