H. Kubinyi

发表

QSAR : Hansch analysis and related approaches

H. Kubinyi, 1993 .

QSAR: Hansch Analysis and Related Approaches: Kubinyi/QSAR

H. Kubinyi, 1993 .

Variable Selection in QSAR Studies. II. A Highly Efficient Combination of Systematic Search and Evolution

H. Kubinyi, 1994 .

A scoring scheme for discriminating between drugs and nondrugs.

H. Kubinyi, J. Sadowski, 1998, Journal of medicinal chemistry.

Comparative Molecular Field Analysis (CoMFA)

H. Kubinyi, 2002 .

3D QSAR in drug design.

H. Kubinyi, Y. Martin, G. Folkers, 2002 .

Drug research: myths, hype and reality

H. Kubinyi, 2003, Nature Reviews Drug Discovery.

QSAR and 3D QSAR in drug design Part 1: methodology

H. Kubinyi, 1997 .

QSAR and 3D QSAR in drug design Part 2: applications and problems

H. Kubinyi, 1997 .

Hugo Kubinyi, H. Kubinyi, 2002 .

Glossary of terms used in computational drug design (IUPAC Recommendations 1997)

G. Grassy, M. S. Tute, P. Willett, 1997 .

Chance favors the prepared mind--from serendipity to rational drug design.

H Kubinyi, H. Kubinyi, 1999, Journal of receptor and signal transduction research.

Privileged Structures and Analogue‐Based Drug Discovery

Hugo Kubinyi, H. Kubinyi, 2006 .

Structure-based design of enzyme inhibitors and receptor ligands.

H. Kubinyi, 1998, Current opinion in drug discovery & development.

Bioinformatics ‐ From Genomes to Drugs

Thomas Lengauer, R. Mannhold, H. Kubinyi, 2001 .

CALCULATION OF ISOTOPE DISTRIBUTIONS IN MASS SPECTROMETRY. A TRIVIAL SOLUTION FOR A NON-TRIVIAL PROBLEM

H. Kubinyi, 1991 .

Three-dimensional quantitative similarity-activity relationships (3D QSiAR) from SEAL similarity matrices.

H. Kubinyi, F. Hamprecht, T. Mietzner, 1998, Journal of medicinal chemistry.

Free Wilson Analysis. Theory, Applications and its Relationship to Hansch Analysis

Hugo Kubinyi, H. Kubinyi, 1988 .

From Narcosis to Hyperspace: The History of QSAR

Hugo Kubinyi, H. Kubinyi, 2002 .

[The key to the castle. II. Hansch analysis, 3d-QSAR and de novo design].

H. Kubinyi, 1994, Pharmazie in unserer Zeit.

Quantitative structure--activity relationships. 7. The bilinear model, a new model for nonlinear dependence of biological activity on hydrophobic character.

H Kubinyi, H. Kubinyi, 1977, Journal of medicinal chemistry.

The chemical structure of a cocarcinogen and of phorbol isolated from croton oil.

H. Kubinyi, E. Hecker, H. Bresch, 1966, Journal of medicinal chemistry.

Structure and stereochemistry of the tetracyclic diterpene phorbol from croton tiglium L.

H. Bartsch, H. Kubinyi, G. Kreibich, 1967 .

[On the active substances of croton oil. IX. Partial synthesis of active substances in croton oil].

H. Kubinyi, G. Kreibich, H. Thielmann, 1968, Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete.

Animal M o d e l s for H u m a n Cancer Discovery and Development of Navel Therapeutics

R., H. Kubinyi, G., 2016 .

3D QSAR in drug design. Vol. 2, Ligand-protein interactions andmolecular similarity

Gerd Folkers, Hugo Kubinyi, H. Kubinyi, 1998 .

Recommendations for CoMFA Studies and 3D QSAR Publications

Gerhard Klebe, Didier Rognan, Gerd Folkers, 1994 .

Hydrogen Bonding: The Last Mystery in Drug Design?

H. Kubinyi, 2007 .

Bioinformatics ‐ From Genomes to Drugs

Thomas Lengauer, Thomas Lengauer, R. Mannhold, 2001 .

The QSAR and Modelling Society

Han van de Waterbeemd, Hugo Kubinyi, H. Kubinyi, 1996 .

Quantitative structure-activity relationships. IV. Non-linear dependence of biological activity on hydrophobic character: a new model.

H. Kubinyi, 1976, Arzneimittel-Forschung.

QUANTITATIVE STRUCTURE-ACTIVITY RELATIONS. 7. THE BILINEAR MODEL, A NEW MODEL L FOR NONLINEAR DEPENDENCE OF BIOLOGICAL ACTIVITY ON HYDROPHOBIC CHARACTER

H. Kubinyi, H. Kubinyi, 1977 .

Prodrugs: Challenges and Rewards. Parts 1 and 2. Edited by Valentino J. Stella, Ronald T. Borchardt, Michael J. Hageman, Reza Oliyai, Hans Maag, and Jefferson W. Tilley.

H. Kubinyi, 2008 .

QSAR/QSPR Modelling – Finding Rules in Noisy Data?

G. Schneider, H. Kubinyi, F. Darvas, 2006 .

3.40 – Chemogenomics

H. Kubinyi, 2007 .

Lipophilicity and drug activity.

H Kubinyi, H. Kubinyi, 1979, Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques.

Part One Hit Finding and Profiling for Protein Kinases : Assay Development and Screening , Libraries

R. Mannhold, H. Kubinyi, G. Folkers, 2015 .

3D QSAR in drug design : theory, methods and applications

Hugo Kubinyi, H. Kubinyi, 2000 .

Evolutionary variable selection in regression and PLS analyses

Hugo Kubinyi, H. Kubinyi, 1996 .

Chemogenomics in Drug Discovery: A Medicinal Chemistry Perspective

Hugo Kubinyi, H. Kubinyi, G. Müller, 2004 .

Quantitative Structure-Activity Relationships and Crystallography in Industrial Drug Design

H. Kubinyi, H. Kubinyi, 1995 .

Lock and key in the real world: concluding remarks

H. Kubinyi, 1995 .

The Physicochemical Significance of Topological Parameters. A Rebuttal

Hugo Kubinyi, H. Kubinyi, 1995 .

QSAR in Drug Design

Hugo Kubinyi, H. Kubinyi, 2008 .

COMPUTER-AIDED DESIGN

Hugo Kubinyi, H. Kubinyi, 2006 .

Chemogenomics in drug discovery.

H Kubinyi, H. Kubinyi, Hugo Kubinyi, 2006, Ernst Schering Research Foundation workshop.

1 Chemogenomics in Drug Discovery

H. Kubinyi, 2006 .

Proscillaridin‐3′‐acylate

H. Kubinyi, W. Steidle, B. Görlich, 1971 .

Partial synthesis of some cocarcinogens from croton oil.

H. Kubinyi, E. Hecker, 1965, Angewandte Chemie.

Success Stories of Computer‐Aided Design

Hugo Kubinyi, Hugo Kubinyi, H. Kubinyi, 2006 .

Nonlinear dependence of biological activity on hydrophobic character: the bilinear model.

H. Kubinyi, 1979, Il Farmaco; edizione scientifica.

2D QSAR Models: Hansch and Free‚ÄìWilson Analyses

Hugo Kubinyi, H. Kubinyi, 2003 .

Validation and Predictivity of QSAR Models

Hugo Kubinyi, H. Kubinyi, 2004 .

Combinatorial and computational approaches in structure-based drug design.

H Kubinyi, H. Kubinyi, 1998, Current opinion in drug discovery & development.

Quantitative Structure–Activity Relationships in Drug Design

Hugo Kubinyi, H. Kubinyi, 2002 .

Quantitative structure-activity relationships. 2. A mixed approach, based on Hansch and Free-Wilson Analysis.

H. Kubinyi, 1976, Journal of medicinal chemistry.

Virtual Screening - The Road to Success

Hugo Kubinyi, H. Kubinyi, 2006 .

The design of combinatorial libraries.

Hugo Kubinyi, H. Kubinyi, 2002, Drug discovery today.

Strategies and recent technologies in drug discovery.

H. Kubinyi, 1995, Die Pharmazie.

Medicinal Chemistry

H. Kubinyi, H. Böhm, M. Dale, 1963, Nature.

Quantitative structure-activity relationships (QSAR) and molecular modelling in cancer research

Hugo Kubinyi, H. Kubinyi, 2005, Journal of Cancer Research and Clinical Oncology.

Chapter 37 - Glossary of Terms Used in Computational Drug Design (IUPAC Recommendations 1997)

Han van de Waterbeemd, Peter Willett, Gérard Grassy, 1998 .

3.40 – Chemogenomics

H. Kubinyi, 2007 .

H. Kubinyi, 2002 .

Drug Discovery from Side Effects

H. Kubinyi, 2005 .

Quantitative structure-activity relationships. 3.1 A comparison of different Free-Wilson models.

H Kubinyi, H. Kubinyi, O H Kehrhahn, 1976, Journal of medicinal chemistry.

Compatibility of the Free-Wilson and Hansch quantitative structure-activity relations.

H Kubinyi, W. P. Purcell, L. J. Schaad, 1981, Journal of medicinal chemistry.

Quantitative structure-activity relationships. 1. The modified Free-Wilson approach.

H Kubinyi, H. Kubinyi, O H Kehrhahn, 1976, Journal of medicinal chemistry.

Ligand-protein interactions and molecular similarity

Gerd Folkers, Hugo Kubinyi, H. Kubinyi, 1998 .

Glossary of terms used in computational drug design (IUPAC Recommendations 1997)

P. Willett, H. Kubinyi, M. Tute, 1997 .

Quantitative structure-activity relationships. VI. Non-linear dependence of biological activity on hydrophobic character: calculation procedures for bilinear model.

H. Kubinyi, O. Kehrhahn, 1978, Arzneimittel-Forschung.