D. Lewis

D. Lewis, C. Ioannides, R. Walker, 1992, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Steroid hormone receptors and dietary ligands: a selected review

D. Lewis, M. Jacobs, 2002, Proceedings of the Nutrition Society.

Quantitative structure-activity relationship (QSAR) analysis for a series of rodent peroxisome proliferators : Interaction with the mouse liver peroxisome proliferator-activated receptor α (mPPARα)

D. Lewis, B. Lake, 1997 .

Structure activity studies on the induction of peroxisomal enzyme activities by a series of phthalate monoesters in primary rat hepatocyte cultures.

D. Lewis, B. Lake, S. Gangolli, 1986, Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement.

Induction of hepatic microsomal CYP4A activity and of peroxisomal β-oxidation by two non-steroidal anti-inflammatory drugs

D. Lewis, C. Ioannides, G. Gibson, 1994, Archives of Toxicology.

Induction of hepatic CYP1A2 by the oral administration of caffeine to rats: lack of association with the Ah locus.

D. Lewis, C. Ioannides, M. Clifford, 1995, Biochimica et biophysica acta.

Feprazone: an inducer of the P450 II B family of proteins in the rat.

D. Lewis, C. Ioannides, J. Chown, 1990, Journal of biochemical toxicology.

Preferential induction of the rat hepatic P450 I proteins by the food carcinogen 2-amino-3-methyl-imidazo[4,5-f]quinoline.

A. D. Rodrigues, D. Lewis, C. Ioannides, 1989, European Journal of Biochemistry.

Spectral and kinetic studies of the interaction of imidazole anti-fungal agents with microsomal cytochromes P-450.

A. D. Rodrigues, D. Lewis, C. Ioannides, 1987, Xenobiotica; the fate of foreign compounds in biological systems.

Anthraflavic acid is a potent and specific inhibitor of cytochrome P-448 activity.

D. Lewis, C. Ioannides, R. Walker, 1987, Biochimica et biophysica acta.

Molecular modelling of human microsomal epoxide hydrolase (EH) by homology with a fungal (Aspergillus niger) EH crystal structure of 1.8 A resolution: structure-activity relationships in epoxides inhibiting EH activity.

D. Lewis, B. Lake, M. Bird, 2005, Toxicology in vitro : an international journal published in association with BIBRA.

Contribution of CYP1A2 in the hepatic metabolism of melatonin: studies with isolated microsomal preparations and liver slices

D. Lewis, C. Ioannides, D. Skene, 2001, Journal of pineal research.

Oxidative stress: the role of cytochromes P450 in oxygen activation

D. Lewis, 2002 .

Allosteric phenomena in cytochrome P450-catalyzed monooxygenations.

D. Lewis, P. Hlavica, 2001, European journal of biochemistry.

Strain in metal carbides

D. Lewis, D. Gillies, 1967 .

Substrates of Human Cytochromes P4S0 from Families CYP1 and CYP2: Analysis of Enzyme Selectivity and Metabolism

D. Lewis, B. Lake, M. Dickins,, 2004, Drug metabolism and drug interactions.

Molecular modelling of steroidogenic cytochromes P450 from families CYP11, CYP17, CYP19 and CYP21 based on the CYP102 crystal Structure

D. Lewis, P. Lee-Robichaud, 1998, The Journal of Steroid Biochemistry and Molecular Biology.

Safety evaluations of food chemicals by "COMPACT". 1. A study of some acyclic terpenes.

D. Lewis, C. Ioannides, D. Parke, 1994, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Evaluation of 7-benzyloxy-4-trifluoromethylcoumarin, some other 7-hydroxy-4-trifluoromethylcoumarin derivatives and 7-benzyloxyquinoline as fluorescent substrates for rat hepatic cytochrome P450 enzymes

D. Lewis, R. J. Price, A. Renwick, 2001, Xenobiotica; the fate of foreign compounds in biological systems.

Molecular orbital-generated QSARs in a homologous series of alkoxyresorufins and studies of their interactive docking with P450s.

D. Lewis, D. Parke, B. Lake, 1995, Xenobiotica; the fate of foreign compounds in biological systems.

57-Isoform cytochromes P450 for bioconversions

D. Lewis, A. Wiseman, 2007 .

Homology modelling of human cytochromes P450 involved in xenobiotic metabolism and rationalization of substrate selectivity.

D. Lewis, 1999, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Metal toxicity in two rodent species and redox potential: Evaluation of quantitative structure—activity relationships

D. Lewis, D. Parke, M. Dobrota, 1999, Environmental toxicology and chemistry.

Molecular modelling and site-directed mutagenesis on a bovine anti-testosterone monoclonal antibody.

D. Lewis, P. Sanders, B. A. Morris, 1992, Protein engineering.

Role of hepatic and renal cytochrome P-450 IVA1 in the metabolism of lipid substrates.

D. Lewis, G. Gibson, G. Gibson, 1989, Biochemical pharmacology.

INHIBITION OF HUMAN CYP1A2 OXIDATION OF 5,6‐DIMETHYL‐XANTHENONE‐4‐ACETIC ACID BY ACRIDINES: A MOLECULAR MODELLING STUDY

D. Lewis, Shufeng Zhou, P. Kestell, 2005, Clinical and experimental pharmacology & physiology.

A study of the effects of microstrain on the electrode potential and the anodic dissolution of Cu

D. Lewis, D. Northwood, C. E. Pearce, 1969 .

Identification of key residues in rabbit liver microsomal cytochrome P450 2B4: importance in interactions with NADPH-cytochrome P450 reductase.

D. Lewis, K. Achterhold, J. Schulze, 2000, Journal of biochemistry.

Influence of mutation of the amino-terminal signal anchor sequence of cytochrome P450 2B4 on the enzyme structure and electron transfer processes.

D. Lewis, M. Eulitz, J. Schulze, 1998, Journal of biochemistry.

X-ray diffraction line broadening studies of Raney copper and nickel

D. Lewis, C. E. Pearce, 1972 .

Safety aspects of food preservatives.

D. Lewis, D. Parke, 1992, Food additives and contaminants.

The Astronomical Pulse of Global Extinction Events

D. Lewis, J. Dorne, 2006, TheScientificWorldJournal.

Up-regulation of CYP1A/B in rat lung and liver, and human liver precision-cut slices by a series of polycyclic aromatic hydrocarbons; association with the Ah locus and importance of molecular size.

D. Lewis, C. Ioannides, N. Plant, 2008, Toxicology in vitro : an international journal published in association with BIBRA.

Interaction of a series of nitriles with the alcohol-inducible isoform of P450: computer analysis of structure-activity relationships.

D. Lewis, C. Ioannides, D. Parke, 1994, Xenobiotica; the fate of foreign compounds in biological systems.

Effect of structural modification on the inhibitory selectivity of rutaecarpine derivatives on human CYP1A1, CYP1A2, and CYP1B1.

D. Lewis, M. Don, Y. Ueng, 2003, Bioorganic & medicinal chemistry letters.

Quantitative structure–activity relationships (QSARs) within the cytochrome P450 system: QSARs describing substrate binding, inhibition and induction of P450s

David F. V. Lewis, D. Lewis, 2004, InflammoPharmacology.

A rationale for the non-mutagenicity of 2- and 3-aminobiphenyls.

D. Lewis, C. Ioannides, J. Trinick, 1989, Carcinogenesis.

Guide to Cytochromes P450 : structure and function

D. Lewis, 2001 .

The 1990 Pharmaceutical Manufacturers Association of Canada keynote lecture. The role of the cytochromes P450 in the detoxication and activation of drugs and other chemicals.

D. Lewis, C. Ioannides, D. Parke, 1991, Canadian journal of physiology and pharmacology.

Metabolism of coumarin by human P450s: a molecular modelling study.

D. Lewis, B. Lake, Yuko Ito, 2006, Toxicology in vitro : an international journal published in association with BIBRA.

Studies on the acute effects of coumarin and some coumarin derivatives in the rat.

D. Lewis, R. J. Price, B. Lake, 1994, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Molecular pathology of drug-disease interactions in chronic autoimmune inflammatory diseases

D. Lewis, C. Ioannides, D. Parke, 1991, InflammoPharmacology.

Structural characteristics of human P450s involved in drug metabolism: QSARs and lipophilicity profiles.

D. Lewis, D F Lewis, D.F.V. Lewis, 2000, Toxicology.

Studies on the cytochrome P-450 of avocado (Persa americana) mesocarp microsomal fraction

D. Lewis, D. Parke, S. Cottrell, 1990 .

Molecular modelling of cytochrome P4502D6 (CYP2D6) based on an alignment with CYP102: structural studies on specific CYP2D6 substrate metabolism.

M H Tarbit, D. Lewis, M. Tarbit, 1997, Xenobiotica; the fate of foreign compounds in biological systems.

Extrapolation of in vitro antimutagenicity to the in vivo situation: the case for anthraflavic acid.

D. Lewis, C. Ioannides, R. Walker, 1993, Basic life sciences.

BOND STRENGTH IN DIBORIDES OF SOME GROUP IV AND V METALS.

D. Lewis, D. Gillies, 1968 .

Trends in human risk assessment of pharmaceuticals

A. Ragas, D. Lewis, J. Dorne, 2007, Analytical and bioanalytical chemistry.

On the recognition of mammalian microsomal cytochrome P450 substrates and their characteristics: towards the prediction of human p450 substrate specificity and metabolism.

D. Lewis, D F Lewis, 2000, Biochemical pharmacology.

Molecular orbital calculations on solvents and other small molecules: Correlation between electronic and molecular properties ν, αMOL, π*, and β.

D. Lewis, David F.V. Lewis, 1987 .

Interactions between Convergent Afferent Transmitter Systems

F. Bloom, D. Lewis, J. Morrison, 1987 .

Functional interaction of cytochrome P450 with its redox partners: a critical assessment and update of the topology of predicted contact regions.

D. Lewis, J. Schulze, P. Hlavica, 2003, Journal of inorganic biochemistry.

The CYP2 family: models, mutants and interactions.

D. Lewis, D F Lewis, 1998, Xenobiotica; the fate of foreign compounds in biological systems.

Evolution of the cytochrome P450 superfamily: sequence alignments and pharmacogenetics.

D. Lewis, B. Lake, E. Watson, 1998, Mutation research.

Mechanism of the in vitro antimutagenic action of retinol.

D. Lewis, C. Ioannides, R. Walker, 1990, Mutagenesis.

Molecular modelling of mammalian CYP2B isoforms and their interaction with substrates, inhibitors and redox partners.

D. Lewis, B. Lake, B G Lake, 1997, Xenobiotica; the fate of foreign compounds in biological systems.

Validation of a novel molecular orbital approach (COMPACT) for the prospective safety evaluation of chemicals, by comparison with rodent carcinogenicity and Salmonella mutagenicity data evaluated by the U.S. NCI/NTP.

D. Lewis, C. Ioannides, D. Parke, 1993, Mutation research.

Molecular Modelling of CYP2F Substrates: Comparison of Naphthalene Metabolism by Human, Rat and Mouse CYP2F Subfamily Enzymes

Bryce C. Lake, D. Lewis, Y. Ito, 2009, Drug metabolism and drug interactions.

Structure–activity relationship for human cytochrome P450 substrates and inhibitors

David F. V. Lewis, Maurice Dickins, D. Lewis, 2002, Drug metabolism reviews.

Cytochromes P450 in the bioactivation of chemicals.

D. Lewis, C. Ioannides, 2004, Current topics in medicinal chemistry.

Cytochromes P450, Oxygen, and Evolution

D. Lewis, G. Sheridan, 2001, TheScientificWorldJournal.

Cytochrome P4501A (CYP1A) induction in rat and man by the benzodioxino derivative, fluparoxan.

D. Lewis, A. Beresford, J. Ayrton, 1997, Xenobiotica; the fate of foreign compounds in biological systems.

The sequence homologies of cytochromes P-450 and active-site geometries

David F. V. Lewis, Henri Moereels, D. Lewis, 1992, J. Comput. Aided Mol. Des..

Structural requirements at the melatonin receptor

D. Lewis, D. Sugden, N. Chong, 1995, British journal of pharmacology.

Molecular modelling of CYP2B6, the human CYP2B isoform, by homology with the substrate-bound CYP102 crystal structure: evaluation of CYP2B6 substrate characteristics, the cytochrome b5 binding site and comparisons with CYP2B1 and CYP2B4.

M H Tarbit, D. Lewis, B. Lake, 1999, Xenobiotica; the fate of foreign compounds in biological systems.

Molecular modelling of human CYP1B1 substrate interactions and investigation of allelic variant effects on metabolism.

Tsutomu Shimada, Elizabeth M J Gillam, D. Lewis, 2003, Chemico-biological interactions.

Substrate SARs in human P450s.

Maurice Dickins, D. Lewis, David F V Lewis, 2002, Drug discovery today.

Molecular modelling of the rat peroxisome proliferator-activated receptor -α (rPPARα) by homology with the human retinoic acid X receptor α (hRXRα) and investigation of ligand binding interactions I: QSARs

D. Lewis, B. Lake, 1998 .

Molecular modelling of the human estrogen receptor and ligand interactions based on site-directed mutagenesis and amino acid sequence homology

D. Lewis, M. Parker, R. King, 1995, The Journal of Steroid Biochemistry and Molecular Biology.

Hydrogen Bonding in Human P450-Substrate Interactions: A Major Contribution to Binding Affinity

D. Lewis, 2004, TheScientificWorldJournal.

Molecular modelling of CYP2E1 enzymes from rat, mouse and man: an explanation for species differences in butadiene metabolism and potential carcinogenicity, and rationalization of CYP2E substrate specificity.

D. Lewis, D. Parke, M. Bird, 1997, Toxicology.

Homology modelling of CYP2A6 based on the CYP2C5 crystallographic template: enzyme-substrate interactions and QSARs for binding affinity and inhibition.

D. Lewis, B. Lake, P. Goldfarb, 2003, Toxicology in vitro : an international journal published in association with BIBRA.

Molecular modelling of the human cytochrome P450 isoform CYP2A6 and investigations of CYP2A substrate selectivity.

M H Tarbit, D. Lewis, B. Lake, 1999, Toxicology.

Essential requirements for substrate binding affinity and selectivity toward human CYP2 family enzymes.

D. Lewis, 2003, Archives of biochemistry and biophysics.

Modelling Species Selectivity in Rat and Human Cytochrome P450 2D Enzymes

D. Lewis, B. Howlin, G. Edmund, 2013, PloS one.

P450 structures and oxidative metabolism of xenobiotics.

D. Lewis, 2003, Pharmacogenomics.

Interactions between redox partners in various cytochrome P450 systems: functional and structural aspects.

D. Lewis, P. Hlavica, 2000, Biochimica et biophysica acta.

Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the putative active site of the human CYP2E1 isoform.

M H Tarbit, D. Lewis, B. Lake, 2000, Xenobiotica; the fate of foreign compounds in biological systems.

Cytochromes P 450 in the Bioactivation of Chemicals

D. Lewis, C. Ioannides, 2004 .

Molecular Orbital Calculations and Nicotine Metabolism: A Rationale for Experimentally Observed Metabolite Ratios

D. Lewis, J. Gorrod, 2002, Drug metabolism and drug interactions.

Human carcinogens: an evaluation study via the COMPACT and HazardExpert procedures

D. Lewis, M. Jacobs, M. Bird, 2002, Human & experimental toxicology.

Species differences in coumarin metabolism: a molecular modelling evaluation of CYP2A interactions

D. Lewis, B. Lake, B G Lake, 2002, Xenobiotica; the fate of foreign compounds in biological systems.

Cytochromes P450: structure, function and mechanism.

D. Lewis, D. F. V. Lewis, 1996 .

Metabolism of 2,5-bis(trifluoromethyl)-7-benzyloxy-4-trifluoromethylcoumarin by human hepatic CYP isoforms: evidence for selectivity towards CYP3A4

D. Lewis, R. J. Price, A. Renwick, 2001, Xenobiotica; the fate of foreign compounds in biological systems.

Modelling human cytochromes P450 involved in drug metabolism from the CYP2C5 crystallographic template.

D. Lewis, 2002, Journal of inorganic biochemistry.

Homology modelling of human CYP2 family enzymes based on the CYP2C5 crystal structure

D. Lewis, D.F.V. Lewis, 2002, Xenobiotica; the fate of foreign compounds in biological systems.

The deformation and annealing characteristics of germanium and silicon

D. Lewis, E. Wheeler, 1977 .

Damage in gallium arsenide crystals produced by ion implantation, abrasion and ball-milling

D. Lewis, T. Tunkasiri, 1975 .

The effect of temperature on microstrains and crystallite growth in alumina

D. Lewis, E. Wheeler, 1969 .

In vitro metabolism of dexamethasone (DEX) in human liver and kidney: the involvement of CYP3A4 and CYP17 (17,20 LYASE) and molecular modelling studies.

D. Lewis, H. Kroemer, B. K. Park, 1997, Biochemical pharmacology.

Cytochrome P450 Substrate Specificities, Substrate Structural Templates and Enzyme Active Site Geometries

D. Lewis, M. Tarbit, P. Goldfarb, 1999, Drug metabolism and drug interactions.

Molecular modelling of human CYP2C subfamily enzymes CYP2C9 and CYP2C19: rationalization of substrate specificity and site-directed mutagenesis experiments in the CYP2C subfamily.

M H Tarbit, D. Lewis, R. Weaver, 1998, Xenobiotica; the fate of foreign compounds in biological systems.

Three-dimensional models of human and other mammalian microsomal P450s constructed from an alignment with P450102 (P450bm3).

D. Lewis, 1995, Xenobiotica; the fate of foreign compounds in biological systems.

Quantitative structure-activity relationships (QSARs) for substrates of human cytochromes P450 CYP2 family enzymes.

D. Lewis, David F V Lewis, 2004, Toxicology in vitro : an international journal published in association with BIBRA.

Molecular Modelling of CYP2B6 Based on Homology with the CYP2C5 Crystal Structure: Analysis of Enzyme-Substrate Interactions

D. Lewis, P. Goldfarb, M. Dickins,, 2002, Drug metabolism and drug interactions.

Quantitative structure-activity relationships within a homologous series of 7-alkoxyresorufins exhibiting activity towards CYP1A and CYP2B enzymes: molecular modelling studies on key members of the resorufin series with CYP2C5-derived models of human CYP1A1, CYP1A2, CYP2B6 and CYP3A4

D. Lewis, B. Lake, M. Dickins, 2004, Xenobiotica; the fate of foreign compounds in biological systems.

Homology modelling of human CYP2E1 based on the CYP2C5 crystal structure: investigation of enzyme-substrate and enzyme-inhibitor interactions.

D. Lewis, B. Lake, G. Loizou, 2003, Toxicology in vitro : an international journal published in association with BIBRA.

Human CYPs involved in drug metabolism: structures, substrates and binding affinities

Yuko Ito, D. Lewis, Yuko Ito, 2010, Expert opinion on drug metabolism & toxicology.

Non-stoichiometry of boron suboxide (B6O)

D. Lewis, P. M. Bills, 1976 .

Interaction of some peroxisome proliferators with the mouse liver peroxisome proliferator-activated receptor (PPAR): a molecular modelling and quantitative structure-activity relationship (QSAR) study.

D. Lewis, B. Lake, 1993, Xenobiotica; the fate of foreign compounds in biological systems.

Homology modelling of CYP3A4 from the CYP2C5 crystallographic template: analysis of typical CYP3A4 substrate interactions

D. Lewis, B. Lake, P. Goldfarb, 2004, Xenobiotica; the fate of foreign compounds in biological systems.

An evaluation of ondansetron binding interactions with human cytochrome P450 enzymes CYP3A4 and CYP2D6.

D. Lewis, Yuko Ito, P. Goldfarb, 2010, Drug metabolism letters.

Analysis of CYP2D6 substrate interactions by computational methods.

Yuko Ito, D. Lewis, H. Kondo, 2008, Journal of molecular graphics & modelling.

Factors influencing rates and clearance in P450-mediated reactions: QSARs for substrates of the xenobiotic-metabolizing hepatic microsomal P450s.

D. Lewis, M. Dickins, D F V Lewis, 2002, Toxicology.

Comparative studies on the cytochrome p450-associated metabolism and interaction potential of selegiline between human liver-derived in vitro systems.

Alan R Boobis, Laurent Corcos, Magnus Ingelman-Sundberg, 2003, Drug metabolism and disposition: the biological fate of chemicals.

Comparison of the hepatic effects of coumarin, 3,4-dimethylcoumarin, dihydrocoumarin and 6-methylcoumarin in the rat.

D. Lewis, R. J. Price, B. Lake, 1994, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Measurement by X-Ray Diffraction of Macro-Stresses and Micro-Stresses in Titanium and a Titanium Alloy

M. B. Waldron, D. Lewis, J. R. Lee, 1973 .

Molecular modelling of CYP4A subfamily members based on sequence homology with CYP102.

D. Lewis, B. Lake, 1999, Xenobiotica; the fate of foreign compounds in biological systems.

Human cytochromes P450 in the metabolism of drugs: new molecular models of enzyme-substrate interactions.

D. Lewis, Yuko Ito, 2008, Expert opinion on drug metabolism & toxicology.

Pole Figures of the Orientation of Apatite in Bones

D. Lewis, J. P. NIGHTINGALE, D. LEWIS, 1971, Nature.

Molecular modelling and quantitative structure-activity relationship studies on the interaction of omeprazole with cytochrome P450 isozymes.

D. Lewis, B. Lake, B G Lake, 1998, Toxicology.

Molecular modeling of human cytochrome P450–substrate interactions

David F. V. Lewis, D. Lewis, 2002, Drug metabolism reviews.

An assessment of human liver-derived in vitro systems to predict the in vivo metabolism and clearance of almokalant.

R J Edwards, A R Boobis, K J Hoffmann, 2001, Drug metabolism and disposition: the biological fate of chemicals.

Structure-Activity Relationships for Induction of Peroxisomal Enzyme Activities By Phthalate Monoesters in Primary Rat Hepatocyte Cultures

D. Lewis, B. Lake, S. Gangolli, 1987, Toxicology and industrial health.

Quantitative structure-activity relationships (QSARs) for inhibitors and substrates of CYP2B enzymes: importance of compound lipophilicity in explanation of potency differences

D. Lewis, B. Lake, Yuko Ito, 2010, Journal of Enzyme Inhibition and Medicinal Chemistry.

Quantitative structure-activity relationships and COMPACT analysis of a series of food mutagens.

D. Lewis, C. Ioannides, D. Parke, 1995, Food additives and contaminants.

Human P450s involved in drug metabolism and the use of structural modelling for understanding substrate selectivity and binding affinity

D. Lewis, D. F. V. Lewis, Y. Ito, 2009, Xenobiotica; the fate of foreign compounds in biological systems.

Lipophilicity Relationships in Inhibitors of CYP2C9 and CYP2C19 Enzymes

D. Lewis, B. Lake, Yuko Ito, 2006, Journal of enzyme inhibition and medicinal chemistry.

Molecular modelling of the peroxisome proliferator-activated receptor α (PPARα) from human, rat and mouse, based on homology with the human PPARγ crystal structure

D. Lewis, B. Lake, M. Jacobs, 2002 .

Homology modelling of the nuclear receptors: human oestrogen receptorbeta (hERbeta), the human pregnane-X-receptor (PXR), the Ah receptor (AhR) and the constitutive androstane receptor (CAR) ligand binding domains from the human oestrogen receptor alpha (hERalpha) crystal structure, and the human pe

D. Lewis, M. Jacobs, M. Dickins,, 2003, Journal of Steroid Biochemistry and Molecular Biology.

Baseline Lipophilicity Relationships in Human Cytochromes P450 Associated with Drug Metabolism

David F. V. Lewis, D. Lewis, Maruice Dickins, 2003, Drug metabolism reviews.

Molecular modelling of cytochrome CYP1A1: a putative access channel explains differences in induction potency between the isomers benzo(a)pyrene and benzo(e)pyrene, and 2- and 4-acetylaminofluorene.

D. Lewis, C. Ioannides, D. Parke, 1994, Toxicology letters.

The genotoxicity of benzanthracenes: a quantitative structure-activity study.

D. Lewis, D. Parke, 1995, Mutation research.

Cytochrome P450 structures and their substrate interactions

Yuko Ito, D. Lewis, Yuko Ito, 2005 .

Computer graphics analysis of the interaction of alkoxy methylenedioxybenzenes with cytochromes P4501.

D. Lewis, C. Ioannides, D. Parke, 1995, Toxicology letters.

COMPACT: a structural approach to the modelling of cytochromes P450 and their interactions with xenobiotics

D. Lewis, David F.V. Lewis, 2001 .

Quantitative structure-activity relationships in substrates, inducers, and inhibitors of cytochrome P4501 (CYP1).

D. Lewis, D. F. Lewis, D F Lewis, 1997, Drug metabolism reviews.

The use of computers in the safety evaluation of drugs and other chemicals

D. Lewis, C. Ioannides, D. Parke, 1994, European Journal of Drug Metabolism and Pharmacokinetics.

Molecular modelling of CYP3A4 from an alignment with CYP102: identification of key interactions between putative active site residues and CYP3A-specific chemicals.

M H Tarbit, D. Lewis, M. Tarbit, 1996, Xenobiotica; the fate of foreign compounds in biological systems.

Molecular orbital calculations on tumor‐inhibitory nitrosoureas: QSARs

D. Lewis, 1988 .

Quantitative Structure-Activity Relationships (QSARs) Within Series of Inhibitors for Mammalian Cytochromes P450 (CYPs)

Maurice Dickins, D. Lewis, M. Dickins, 2001, Journal of enzyme inhibition.

Quantitative structure – activity relationships ( QSARs ) within the cytochrome P 450 system : QSARs describing substrate binding , inhibition and induction of P 450 s

D. Lewis, DAVID F. V. LEWIS, 2022 .

Structural Models for Cytochrome P450—Mediated Catalysis

D. Lewis, 2003, TheScientificWorldJournal.

Modelling human cytochrome P450-substrate interactions.

D. Lewis, 2002, Ernst Schering Research Foundation workshop.

Comparison between rodent carcinogenicity test results of 44 chemicals and a number of predictive systems.

D. Lewis, D F Lewis, 1994, Regulatory toxicology and pharmacology : RTP.

The mutagenicity and interactions of 2- and 4-(acetylamino)fluorene with cytochrome P450 and the aromatic hydrocarbon receptor may explain the difference in their carcinogenic potency.

D. Lewis, C. Ioannides, T. Gray, 1993, Chemical research in toxicology.

Molecular orbital calculations on tumour-inhibitory phenyl aziridines: QSARs.

D. Lewis, D. F. Lewis, 1989, Xenobiotica; the fate of foreign compounds in biological systems.

Molecular electrostatic potential energies and methylation of DNA bases: a molecular orbital-generated quantitative structure-activity relationship.

D. Lewis, D. F. Lewis, D F Lewis, 1987, Xenobiotica; the fate of foreign compounds in biological systems.

Human cytochromes P450 in the metabolism of drugs: new molecular models of enzyme–substrate interactions

Yuko Ito, D. Lewis, Yuko Ito, 2008 .

Quantitative structure–activity relationships (QSARs) in CYP3A4 inhibitors: The importance of lipophilic character and hydrogen bonding

Maurice Dickins, D. Lewis, B. Lake, 2006, Journal of enzyme inhibition and medicinal chemistry.

Human P450s in the metabolism of drugs: molecular modelling of enzyme–substrate interactions

D. Lewis, David FV Lewis, 2005, Expert opinion on drug metabolism & toxicology.

QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS (QSARs) WITHIN CYTOCHROMES P450 2B (CYP2B) SUBFAMILY ENZYMES: THE IMPORTANCE OF LIPOPHILICITY FOR BINDING AND METABOLISM

D. Lewis, B. Lake, P. Anzenbacher, 2006, Drug metabolism and drug interactions.

Molecular Modelling of the Mouse Cytochrome P450 CYP2F2 Based on the CYP102 Crystal Structure Template and Selective CYP2F2 Substrate Interactions

D. Lewis, Paul T. Bailey, L. Low, 2002, Drug metabolism and drug interactions.

Quantitative structure-activity relationships (QSARs) in inhibitors of various cytochromes P450: The importance of compound lipophilicity

D. Lewis, B. Lake, M. Dickins, 2007, Journal of enzyme inhibition and medicinal chemistry.

Transformation of vaterite to calcite during grinding

D. Lewis, D. Northwood, 1968 .

Long-Range Effects of a Peripheral Mutation on the Enzymatic Activity of Cytochrome P450 1A2

Tao Zhang, Dongqing Wei, Limin Angela Liu, 2011, J. Chem. Inf. Model..

Enzyme-Substrate Binding Interaction Energies and Their Application to the Cytochrome P450 System

D. Lewis, Yuko Ito, P. Goldfarb, 2008 .