P. Bonaventure

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Nuclei and subnuclei gene expression profiling in mammalian brain

P. Bonaventure, Hongqing Guo, Bin Tian, 2002, Brain Research.

Effects of SB-269970, a 5-HT7 receptor antagonist, in mouse models predictive of antipsychotic-like activity

P. Bonaventure, J. Atack, R. Galici, 2008, Behavioural pharmacology.

Pre-clinical characterization of aryloxypyridine amides as histamine H3 receptor antagonists: identification of candidates for clinical development.

P. Bonaventure, Kiev S. Ly, T. Lovenberg, 2010, Bioorganic & medicinal chemistry letters.

Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists.

P. Bonaventure, Sandy J. Wilson, T. Lovenberg, 2009, European journal of medicinal chemistry.

2-Aryloxymethylmorpholine histamine H(3) antagonists.

P. Bonaventure, Kiev S. Ly, N. Carruthers, 2008, Bioorganic & medicinal chemistry letters.

Histamine H3 receptor antagonists: from target identification to drug leads.

P. Bonaventure, F. Kamme, T. Lovenberg, 2007, Biochemical pharmacology.

In vivo Calcium Imaging Reveals That Cortisol Treatment Reduces the Number of Place Cells in Thy1-GCaMP6f Transgenic Mice

J. Nassi, S. Otte, P. Bonaventure, 2019, Front. Neurosci..

Direct Imaging of Hippocampal Epileptiform Calcium Motifs Following Kainic Acid Administration in Freely Behaving Mice

Mark J. Schnitzer, E. Paxon Frady, Jonathan J. Nassi, 2016, Front. Neurosci..

Identification of the domains in RXFP4 (GPCR142) responsible for the high affinity binding and agonistic activity of INSL5 at RXFP4 compared to RXFP3 (GPCR135).

P. Bonaventure, F. Kamme, T. Lovenberg, 2008, European journal of pharmacology.

Co-localization of 5-HT1B- and 5-HT1D receptor mRNA in serotonergic cell bodies in guinea pig dorsal raphé nucleus: a double labeling in situ hybridization histochemistry study

P. Bonaventure, J. Leysen, X. Langlois, 1998, Neuroscience Letters.

Re-evaluation of Adrenocorticotropic Hormone and Melanocyte Stimulating Hormone Activation of GPR139 in Vitro

P. Bonaventure, C. Dvorak, T. Lovenberg, 2018, Front. Pharmacol..

Identification and SAR of Glycine Benzamides as Potent Agonists for the GPR139 Receptor.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2015, ACS medicinal chemistry letters.

Novel tetrahydropyrido[3,2-c]pyrroles as 5-HT(7) antagonists.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2011, Bioorganic & medicinal chemistry letters.

Selective orexin receptor antagonists.

T. P. Lebold, P. Bonaventure, B. Shireman, 2013, Bioorganic & medicinal chemistry letters.

Metabolic and Neuroendocrine Responses to RXFP3 Modulation in the Central Nervous System

P. Bonaventure, T. Lovenberg, Changlu Liu, 2009, Annals of the New York Academy of Sciences.

Novel tetrahydroisoquinolines are histamine H3 antagonists and serotonin reuptake inhibitors.

P. Bonaventure, J. A. Jablonowski, Kiev S. Ly, 2007, Bioorganic & medicinal chemistry letters.

The future antihistamines: histamine H3 and H4 receptor ligands.

P. Bonaventure, R. Thurmond, Fuqu Yu, 2010, Advances in experimental medicine and biology.

In Vitro Pharmacological Characterization of RXFP3 Allosterism: An Example of Probe Dependency

P. Bonaventure, S. Sutton, M. Čík, 2012, PloS one.

Novel Octahydropyrrolo[3,4-c]pyrroles Are Selective Orexin-2 Antagonists: SAR Leading to a Clinical Candidate.

P. Bonaventure, Kiev S. Ly, T. Lovenberg, 2015, Journal of medicinal chemistry.

Characterization of JNJ-42847922, a Selective Orexin-2 Receptor Antagonist, as a Clinical Candidate for the Treatment of Insomnia

P. Bonaventure, T. Lovenberg, N. Carruthers, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement

P. Bonaventure, T. Lovenberg, N. Carruthers, 2011, Psychopharmacology.

JNJ-10181457, a selective non-imidazole histamine H3 receptor antagonist, normalizes acetylcholine neurotransmission and has efficacy in translational rat models of cognition

P. Bonaventure, T. Lovenberg, R. Galici, 2009, Neuropharmacology.

Putative role of GPR139 on sleep modulation using pharmacological and genetic rodent models.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2020, European journal of pharmacology.

Chimeric, mutant orexin receptors show key interactions between orexin receptors, peptides and antagonists.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2011, European journal of pharmacology.

The Schizophrenia Variant V1282F in SCN2A Causes Functional Impairment of NaV1.2

P. Bonaventure, T. Lovenberg, B. Kohlnhofer, 2021, Journal of Schizophrenia Research.

Novel methyl substituted 1-(5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanones are P2X7 antagonists.

P. Bonaventure, N. Carruthers, Hong Ao, 2015, Bioorganic & medicinal chemistry letters.

Translational evaluation of novel selective orexin-1 receptor antagonist JNJ-61393215 in an experimental model for panic in rodents and humans

T. P. Lebold, P. Bonaventure, W. Drevets, 2020, Translational Psychiatry.

Characterization of N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyano-phenyl)-N-[1-(2-cyclopentyl-ethyl)-piperidin-4yl]acrylamide (JNJ-5207787), a Small Molecule Antagonist of the Neuropeptide Y Y2 Receptor

P. Bonaventure, J. A. Jablonowski, T. Lovenberg, 2004, Journal of Pharmacology and Experimental Therapeutics.

G-Protein-Coupled Receptor (GPCR)-142 Does Not Contribute to Relaxin-3 Binding in the Mouse Brain: Further Support that Relaxin-3 Is the Physiological Ligand for GPCR135

P. Bonaventure, T. Lovenberg, Jiejun Wu, 2006, Neuroendocrinology.

Substituted Azabicyclo[2.2.1]heptanes as Selective Orexin-1 Antagonists: Discovery of JNJ-54717793.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2020, ACS medicinal chemistry letters.

Orexin-1 receptor blockade dysregulates REM sleep in the presence of orexin-2 receptor antagonism

P. Bonaventure, T. Lovenberg, C. Dugovic, 2014, Front. Neurosci..

Endogenous dopamine limits the binding of antipsychotic drugs to D3 receptors in the rat brain: a quantitative autoradiographic study

P. Bonaventure, J. Leysen, A. Schotte, 1996, The Histochemical Journal.

Translational evaluation of JNJ-18038683, a 5-HT7 receptor antagonist, on REM sleep and in major depressive disorder

P. Bonaventure, C. Dvorak, T. Lovenberg, 2012 .

REM sleep and in major depressive disorder

P. Bonaventure, W. Chai, C. Dvorak, 2012 .

4-Methyl-6,7-dihydro-4H-triazolo[4,5-c]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2017, Journal of medicinal chemistry.

A novel radioligand for the ATP-gated ion channel P2X7: [3H] JNJ-54232334.

P. Bonaventure, T. Lovenberg, N. Carruthers, 2015, European journal of pharmacology.

Neuropharmacology and analgesia A novel radioligand for the ATP-gated ion channel P 2 X 7 : [ 3 H ] JNJ-54232334

P. Bonaventure, T. Lovenberg, N. Carruthers, 2015 .

Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X7 Antagonists.

P. Bonaventure, N. Carruthers, Hong Ao, 2013, ACS medicinal chemistry letters.

In vitro and in vivo characterization of JNJ-31020028 (N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide), a selective brain penetrant small molecule antagonist of the neuropeptide Y Y2 receptor

P. Bonaventure, C. Dvorak, T. Lovenberg, 2010, Psychopharmacology.

Substituted 5,6-(Dihydropyrido[3,4-d]pyrimidin-7(8H)-yl)-methanones as P2X7 Antagonists.

P. Bonaventure, T. Lovenberg, N. Carruthers, 2016, ACS chemical neuroscience.

Pharmacological Characterization of Relaxin-3/INSL7 Receptors GPCR135 and GPCR142 from Different Mammalian Species

P. Bonaventure, T. Lovenberg, Changlu Liu, 2005, Journal of Pharmacology and Experimental Therapeutics.

Novel non-peptidic neuropeptide Y Y2 receptor antagonists.

P. Bonaventure, J. A. Jablonowski, W. Chai, 2004, Bioorganic & medicinal chemistry letters.

dantly expressed NPY receptor subtypes in the brain

P. Bonaventure, J. A. Jablonowski, T. Lovenberg, 2004 .

Characterization of JNJ-5207787, a small molecule antagonist of the neuropeptide Y Y 2 receptor

P. Bonaventure, T. Lovenberg, N. Carruthers, 2003 .

JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats

E. Levin, P. Bonaventure, T. Lovenberg, 2011, Psychopharmacology.

Pharmacological characterization of JNJ-28583867, a histamine H(3) receptor antagonist and serotonin reuptake inhibitor.

P. Bonaventure, Sandy J. Wilson, T. Lovenberg, 2007, European journal of pharmacology.

Hypothalamic orexin’s role in exacerbated cutaneous vasodilation responses to an anxiogenic stimulus in a surgical menopause model

P. Bonaventure, A. Shekhar, J. Carpenter, 2016, Psychoneuroendocrinology.

Probing the Functional Domains of Relaxin‐3 and the Creation of a Selective Antagonist for RXFP3/GPCR135 over Relaxin Receptor RXFP1/LGR7

P. Bonaventure, T. Lovenberg, J. Wade, 2009, Annals of the New York Academy of Sciences.

Recent Progress in Relaxin‐3‐Related Research

P. Bonaventure, T. Lovenberg, Changlu Liu, 2005, Annals of the New York Academy of Sciences.

Discovery and SAR Studies of 2-Alkyl-3-phenyl-2,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepines as 5-HT7/2 Inhibitors Leading to the Identification of a Clinical Candidate.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2020, Bioorganic & medicinal chemistry letters.

Genomic and functional conservation of sedative-hypnotic targets in the zebrafish

Emmanuel Mignot, Pascal Bonaventure, P. Bonaventure, 2007, Pharmacogenetics and genomics.

Zolpidem Reduces Hippocampal Neuronal Activity in Freely Behaving Mice: A Large Scale Calcium Imaging Study with Miniaturized Fluorescence Microscope

Mark J. Schnitzer, Yaniv Ziv, Sujin Yun, 2014, PloS one.

Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists.

P. Bonaventure, Sandy J. Wilson, T. Lovenberg, 2009, European journal of medicinal chemistry.

Synthesis and biological activity of piperazine and diazepane amides that are histamine H3 antagonists and serotonin reuptake inhibitors.

P. Bonaventure, Kiev S. Ly, Sandy J. Wilson, 2008, Bioorganic & medicinal chemistry letters.

Diamine-based human histamine H3 receptor antagonists: (4-aminobutyn-1-yl)benzylamines.

P. Bonaventure, J. A. Jablonowski, C. Dvorak, 2009, European journal of medicinal chemistry.

Pharmacologic Characterization of JNJ-42226314, [1-(4-Fluorophenyl)indol-5-yl]-[3-[4-(thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone, a Reversible, Selective, and Potent Monoacylglycerol Lipase Inhibitor

P. Bonaventure, T. Lovenberg, P. Connolly, 2019, The Journal of Pharmacology and Experimental Therapeutics.

The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y₂ receptor.

P. Bonaventure, J. A. Jablonowski, C. Dvorak, 2011, Bioorganic & medicinal chemistry letters.

OREXIN 1 AND 2 RECEPTOR INVOLVEMENT IN CO2‐INDUCED PANIC‐ASSOCIATED BEHAVIOR AND AUTONOMIC RESPONSES

P. Bonaventure, J. Renger, C. Winrow, 2015, Depression and anxiety.

A Selective Orexin-1 Receptor Antagonist Attenuates Stress-Induced Hyperarousal without Hypnotic Effects

T. P. Lebold, P. Bonaventure, T. Lovenberg, 2015, The Journal of Pharmacology and Experimental Therapeutics.

In vitro receptor binding and in vivo receptor occupancy in rat and guinea pig brain: risperidone compared with antipsychotics hitherto used.

P. Bonaventure, J. Leysen, A. Schotte, 1995, Japanese journal of pharmacology.

8-OH-DPAT acts on both 5-HT1A and 5-HT7 receptors to induce hypothermia in rodents.

P. Bonaventure, J. Sutcliffe, T. Lovenberg, 2004, European journal of pharmacology.

Identification and characterization of select oxysterols as ligands for GPR17

P. Bonaventure, Changlu Liu, C. Kuei, 2022, British journal of pharmacology.

Orexin Depolarizes Central Amygdala Neurons via Orexin Receptor 1, Phospholipase C and Sodium-Calcium Exchanger and Modulates Conditioned Fear

P. Bonaventure, A. Shekhar, S. Bhatnagar, 2018, Front. Neurosci..

Radioligand binding analysis of knockout mice reveals 5-hydroxytryptamine7 receptor distribution and uncovers 8-hydroxy-2-(di-n-propylamino)tetralin interaction with α2 adrenergic receptors

P. Bonaventure, J. Sutcliffe, T. Lovenberg, 2004, Neuroscience.

The novel, selective, brain-penetrant neuropeptide Y Y2 receptor antagonist, JNJ-31020028, tested in animal models of alcohol consumption, relapse, and anxiety.

E. Levin, P. Bonaventure, T. Lovenberg, 2011, Alcohol.

Relaxin-3/Insulin-Like Peptide 5 Chimeric Peptide, a Selective Ligand for G Protein-Coupled Receptor (GPCR)135 and GPCR142 over Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 7

P. Bonaventure, T. Lovenberg, Changlu Liu, 2005, Molecular Pharmacology.

Blockade of Orexin-1 Receptors Attenuates Orexin-2 Receptor Antagonism-Induced Sleep Promotion in the Rat

P. Bonaventure, C. Dvorak, T. Lovenberg, 2009, Journal of Pharmacology and Experimental Therapeutics.

5-HT7 receptor deletion enhances REM sleep suppression induced by selective serotonin reuptake inhibitors, but not by direct stimulation of 5-HT1A receptor

P. Bonaventure, T. Lovenberg, C. Dugovic, 2009, Neuropharmacology.

Selective Blockade of 5-Hydroxytryptamine (5-HT)7 Receptors Enhances 5-HT Transmission, Antidepressant-Like Behavior, and Rapid Eye Movement Sleep Suppression Induced by Citalopram in Rodents

P. Bonaventure, T. Lovenberg, J. Atack, 2007, Journal of Pharmacology and Experimental Therapeutics.

Antipsychotics and neuropeptides: The atypical profile of CI-943 and its relationship to neurotensin

P. Bonaventure, J. Liégeois, J. Damas, 1995, Neuroscience & Biobehavioral Reviews.

Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ‐47965567

P. Bonaventure, T. Lovenberg, Hong Ao, 2013, British journal of pharmacology.

Structure and function of the amygdaloid NPY system: NPY Y2 receptors regulate excitatory and inhibitory synaptic transmission in the centromedial amygdala

P. Bonaventure, H. Herzog, G. Lach, 2015, Brain Structure and Function.

Neuropeptide S stimulates dopaminergic neurotransmission in the medial prefrontal cortex

P. Bonaventure, R. Reinscheid, Naoe Okamura, 2010, Journal of neurochemistry.

Mutagenesis studies of neuropeptide S identify a suitable peptide tracer for neuropeptide S receptor binding studies and peptides selectively activating the I(107) variant of human neuropeptide S receptor.

P. Bonaventure, T. Lovenberg, Changlu Liu, 2010, European journal of pharmacology.

GPR139 and Dopamine D2 Receptor Co-express in the Same Cells of the Brain and May Functionally Interact

P. Bonaventure, T. Lovenberg, Changlu Liu, 2019, Front. Neurosci..

Recent Advances on the 5-HT5A, 5-HT6 and 5-HT7 Receptors

P. Bonaventure, N. Carruthers, B. Shireman, 2008 .

In vivo Characterization of a Selective, Orally Available, and Brain Penetrant Small Molecule GPR139 Agonist

P. Bonaventure, T. Lovenberg, Changlu Liu, 2019, Front. Pharmacol..

Chronic administration of the Y2 receptor antagonist, JNJ-31020028, induced anti-depressant like-behaviors in olfactory bulbectomized rat

P. Bonaventure, R. Quirion, Y. Dumont, 2012, Neuropeptides.

R3(BΔ23–27)R/I5 Chimeric Peptide, a Selective Antagonist for GPCR135 and GPCR142 over Relaxin Receptor LGR7

P. Bonaventure, F. Kamme, T. Lovenberg, 2007, Journal of Biological Chemistry.

INSL5 Is a High Affinity Specific Agonist for GPCR142 (GPR100)*

P. Bonaventure, F. Kamme, T. Lovenberg, 2005, Journal of Biological Chemistry.

Autoradiographic mapping of 5-HT1B and 5-HT1D receptors in the post mortem human brain using [3H]GR 125743

Katarina Varnäs, Göran Sedvall, Håkan Hall, 2001, Brain Research.

Autoradiographic mapping of 5-HT1B- and 5-HT1D receptors in human brain using [3H]alniditan, a new radioligand.

A Schotte, P. Bonaventure, J. Leysen, 1997, Receptors & channels.

Reconsideration of 5-hydroxytryptamine (5-HT)(7) receptor distribution using [(3)H]5-carboxamidotryptamine and [(3)H]8-hydroxy-2-(di-n-propylamino)tetraline: analysis in brain of 5-HT(1A) knockout and 5-HT(1A/1B) double-knockout mice.

Xavier Langlois, Rene Hen, Pascal Bonaventure, 2002, The Journal of pharmacology and experimental therapeutics.

The discovery of potent selective NPY Y(2) antagonists.

P. Bonaventure, W. Chai, T. Lovenberg, 2013, Bioorganic & medicinal chemistry letters.

Pharmacology of a Novel Central Nervous System–Penetrant P2X7 Antagonist JNJ-42253432

P. Bonaventure, T. Lovenberg, N. Carruthers, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Mapping of serotonin 5‐HT4 receptor mRNA and ligand binding sites in the post‐mortem human brain

P. Bonaventure, M. Jurzak, J. Leysen, 2000, Synapse.

Utilizing Miniature Fluorescence Microscopy to Image Hippocampal Place Cell Ensemble Function in Thy1.GCaMP6f Transgenic Mice

Tim Indersmitten, Tamara Berdyyeva, Leah Aluisio, 2018, Current protocols in pharmacology.

Pharmacological characterization of the selective orexin-1 receptor antagonist JNJ-61393215 in healthy volunteers

P. Bonaventure, W. Drevets, W. Drevets, 2023, Journal of psychopharmacology.

Evaluation of JNJ-54717793 a Novel Brain Penetrant Selective Orexin 1 Receptor Antagonist in Two Rat Models of Panic Attack Provocation

P. Bonaventure, T. Lovenberg, A. Shekhar, 2017, Front. Pharmacol..

Selective Inhibition of Orexin-2 Receptors Prevents Stress-Induced ACTH Release in Mice

P. Bonaventure, T. Lovenberg, C. Dugovic, 2017, Frontiers in Behavioral Neuroscience.

In-vitro and in-vivo characterization of JNJ-7925476, a novel triple monoamine uptake inhibitor.

Brian Lord, Leah Aluisio, Pascal Bonaventure, 2008, European journal of pharmacology.

Screening for modulators of neural network activity in 3D human iPSC-derived cortical spheroids

P. Bonaventure, T. Lovenberg, O. Guicherit, 2020, PloS one.

Molecular and pharmacological characterization of serotonin 5-HT2A and 5-HT2B receptor subtypes in dog.

P. Bonaventure, F. Kamme, T. Lovenberg, 2005, European journal of pharmacology.

Pharmacological Blockade of Serotonin 5-HT7 Receptor Reverses Working Memory Deficits in Rats by Normalizing Cortical Glutamate Neurotransmission

Brian Lord, Leah Aluisio, Pascal Bonaventure, 2011, PloS one.

Distribution of relaxin‐3 and RXFP3 within arousal, stress, affective, and cognitive circuits of mouse brain

P. Bonaventure, S. Sutton, A. Gundlach, 2010, The Journal of comparative neurology.

Relaxin-3 in GABA projection neurons of nucleus incertus suggests widespread influence on forebrain circuits via G-protein-coupled receptor-135 in the rat

P. Bonaventure, S. Sutton, A. Gundlach, 2007, Neuroscience.

Structure and function of the amygdaloid NPY system: NPY Y2 receptors regulate excitatory and inhibitory synaptic transmission in the centromedial amygdala

P. Bonaventure, G. Sperk, H. Herzog, 2015, Brain Structure and Function.

Comparison of the ex vivo receptor occupancy profile of ketamine to several NMDA receptor antagonists in mouse hippocampus.

P. Bonaventure, T. Lovenberg, X. Langlois, 2013, European journal of pharmacology.

NPY Y2 receptors in the central amygdala reduce cued but not contextual fear

P. Bonaventure, S. Weger, R. Heilbronn, 2015, Neuropharmacology.

Corrigendum to “Hypothalamic orexin's role in exacerbated cutaneous vasodilation responses to an anxiogenic stimulus in a surgical menopause model” [Psychoneuroendocrinology 65 (2016) 127–137]

P. Bonaventure, A. Shekhar, J. Carpenter, 2016, Psychoneuroendocrinology.

R3(BDelta23 27)R/I5 chimeric peptide, a selective antagonist for GPCR135 and GPCR142 over relaxin receptor LGR7: in vitro and in vivo characterization.

P. Bonaventure, F. Kamme, T. Lovenberg, 2007, The Journal of biological chemistry.

The Zinc Transporter SLC39A7 (ZIP7) Is Essential for Regulation of Cytosolic Zinc Levels

P. Bonaventure, S. Kushner, T. Lovenberg, 2018, Molecular Pharmacology.

Neurochemical profile of orexin receptor antagonists : awakening the neurochemistry of sleep

P. Bonaventure, C. Dvorak, T. Lovenberg, 2008 .

Pharmacological or genetic orexin1 receptor inhibition attenuates MK-801 induced glutamate release in mouse cortex

P. Bonaventure, T. Lovenberg, Tamara Berdyyeva, 2014, Front. Neurosci..

5HT1B and 5HT1D receptor mRNA differential co‐localization with peptide mRNA in the guinea pig trigeminal ganglion

P. Bonaventure, J. Leysen, W. Luyten, 1998, Neuroreport.

Detailed mapping of serotonin 5-HT1B and 5-HT1D receptor messenger RNA and ligand binding sites in guinea-pig brain and trigeminal ganglion: clues for function

P. Bonaventure, M. Jurzak, J. Leysen, 1997, Neuroscience.

2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2008, Bioorganic & medicinal chemistry letters.

Distribution of G-Protein-Coupled Receptor (GPCR)135 Binding Sites and Receptor mRNA in the Rat Brain Suggests a Role for Relaxin-3 in Neuroendocrine and Sensory Processing

P. Bonaventure, B. Roland, T. Lovenberg, 2005, Neuroendocrinology.

Selective pharmacological blockade of the 5-HT7 receptor attenuates light and 8-OH-DPAT induced phase shifts of mouse circadian wheel running activity

P. Bonaventure, C. Dvorak, T. Lovenberg, 2015, Front. Behav. Neurosci..

Humanization of mouse 5-hydroxytryptamine1B receptor gene by homologous recombination: in vitro and in vivo characterization.

P. Bonaventure, M. Bakker, J. Leysen, 1999, Molecular pharmacology.

Molecular cloning, expression and tissue distribution of glial-cell-line-derived neurotrophic factor family receptor alpha-3 (GFRalpha-3).

P. Bonaventure, J. Leysen, M. Pangalos, 1998, European journal of biochemistry.

Novel benzamide-based histamine h3 receptor antagonists: the identification of two candidates for clinical development.

P. Bonaventure, Kiev S. Ly, T. Lovenberg, 2015, ACS Medicinal Chemistry Letters.

Relaxin Family Peptides and Receptors in Mammalian Brain

P. Bonaventure, T. Lovenberg, A. Lawrence, 2009, Annals of the New York Academy of Sciences.

Translational Evaluation of JNJ-18038683, a 5-Hydroxytryptamine Type 7 Receptor Antagonist, on Rapid Eye Movement Sleep and in Major Depressive Disorder

P. Bonaventure, C. Dvorak, T. Lovenberg, 2012, Journal of Pharmacology and Experimental Therapeutics.

1 R 3 ( B ∆ 23-27 ) R / I 5 CHIMERIC PEPTIDE , A SELECTIVE ANTAGONIST FOR GPCR 135 AND GPCR 142 OVER RELAXIN RECEPTOR LGR 7 : IN VITRO AND IN VIVO CHARACTERIZATION

P. Bonaventure, F. Kamme, Jiejun Wu, 2007 .

Novel tetrahydropyrido[3,2-c]pyrroles as 5-HT(7) antagonists.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2011, Bioorganic & medicinal chemistry letters.

Mutagenesis of GPR139 reveals ways to create gain or loss of function receptors

P. Bonaventure, T. Lovenberg, Jiejun Wu, 2019, Pharmacology research & perspectives.