P. Higgs

发表

Bayesian phylogenetics using an RNA substitution model applied to early mammalian evolution.

M. Rattray, H. Jow, C. Hudelot, 2002, Molecular biology and evolution.

Barrier heights between ground states in a model of RNA secondary structure

P. Higgs, S. Morgan, 1998 .

RNA sequence evolution with secondary structure constraints: comparison of substitution rate models using maximum-likelihood methods.

D. Hoyle, P. Higgs, N. Savill, 2001, Genetics.

Stochastic models for species formation in evolving populations

B. Derrida, P. Higgs, 1991 .

RNA secondary structure: physical and computational aspects

P. Higgs, 2000, Quarterly Reviews of Biophysics.

Further Topics in Molecular Evolution and Phylogenetics

P. Higgs, T. Attwood, 2013 .

A four-column theory for the origin of the genetic code: tracing the evolutionary pathways that gave rise to an optimized code

P. Higgs, 2009, Biology Direct.

Codon usage in mitochondrial genomes: distinguishing context-dependent mutation from translational selection.

P. Higgs, W. Jia, Paul G Higgs, 2008, Molecular biology and evolution.

Population genetics without intraspecific data.

Hirohisa Kishino, Jeffrey L Thorne, P. Higgs, 2007, Molecular biology and evolution.

The Mechanisms of Codon Reassignments in Mitochondrial Genetic Codes

Xiaoguang Yang, Supratim Sengupta, Paul G. Higgs, 2007, Journal of Molecular Evolution.

RNA-Based Phylogenetic Methods

M. Rattray, P. Higgs, 2005 .

Factors affecting the errors in the estimation of evolutionary distances between sequences.

D. Hoyle, P. Higgs, D C Hoyle, 2003, Molecular biology and evolution.

RNA-based phylogenetic methods: application to mammalian mitochondrial RNA sequences.

Magnus Rattray, Howsun Jow, Vivek Gowri-Shankar, 2003, Molecular phylogenetics and evolution.

RNA secondary structure: a comparison of real and random sequences

Paul Higgs, P. Higgs, 1993 .

Thermodynamic properties of transfer RNA: a computational study

P. Higgs, 1995 .

The accumulation of mutations in asexual populations and the structure of genealogical trees in the presence of selection

P. Higgs, G. Woodcock, 1995 .

Population evolution on a multiplicative single-peak fitness landscape.

P. Higgs, G. Woodcock, P G Higgs, 1996, Journal of theoretical biology.

Evidence for kinetic effects in the folding of large RNA molecules

Paul Higgs, Steven R. Morgan, P. Higgs, 1996 .

Compensatory neutral mutations and the evolution of RNA.

Paul Higgs, P. Higgs, 1998 .

A population genetics model for multiple quantitative traits exhibiting pleiotropy and epistasis.

P. Higgs, C. F. Taylor, P G Higgs, 2000, Journal of theoretical biology.

Genetic distance and species formation in evolving populations

Bernard Derrida, Paul G. Higgs, B. Derrida, 1992, Journal of Molecular Evolution.

Compensatory neutral mutations and the evolution of RNA

P. Higgs, 2004, Genetica.

Bioinformatics and Molecular Evolution

P. Higgs, T. Attwood, Damian Counsell, 2004, Comparative and Functional Genomics.

The RNA World: molecular cooperation at the origins of life

N. Lehman, P. Higgs, 2014, Nature Reviews Genetics.

Origin of Life, RNA World and

P. Higgs, 2016 .

Origin of Self-Replicating Biopolymers: Autocatalytic Feedback Can Jump-Start the RNA World

P. Higgs, Meng Wu, 2009, Journal of Molecular Evolution.

Deleting species from model food webs

C. Quince, P. Higgs, A. McKane, 2004, q-bio/0401037.

The influence of predator--prey population dynamics on the long-term evolution of food web structure.

B. Drossel, P. Higgs, A. McKane, 2000, Journal of theoretical biology.

The advantages and disadvantages of horizontal gene transfer and the emergence of the first species

P. Higgs, Aaron A. Vogan, 2011, Biology Direct.

Testing the infinitely many genes model for the evolution of the bacterial core genome and pangenome.

P. Higgs, R. Collins, Paul G Higgs, 2012, Molecular biology and evolution.

The Relationship Between the Rate of Molecular Evolution and the Rate of Genome Rearrangement in Animal Mitochondrial Genomes

P. Higgs, Daniel Jameson, W. Xu, 2006, Journal of Molecular Evolution.

A thermodynamic basis for prebiotic amino acid synthesis and the nature of the first genetic code.

P. Higgs, R. Pudritz, Paul G Higgs, 2009, Astrobiology.

Pathways of Genetic Code Evolution in Ancient and Modern Organisms

Supratim Sengupta, Paul G. Higgs, P. Higgs, 2015, Journal of Molecular Evolution.

Evolution of protein interfaces in multimers and fibrils

P. Higgs, S. Setayeshgar, J. Marsh, 2019, The Journal of chemical physics.

Limitation of Trypanosoma brucei parasitaemia results from density-dependent parasite differentiation and parasite killing by the host immune response

P. Higgs, K. Gull, K. Matthews, 2001, Proceedings of the Royal Society of London. Series B: Biological Sciences.

Chemical Evolution and the Evolutionary Definition of Life

P. Higgs, 2017, Journal of Molecular Evolution.

The Role of Templating in the Emergence of RNA from the Prebiotic Chemical Mixture

P. Higgs, Kevin Shi, Andrew S. Tupper, 2017, Life.

Patterns in Protein Families

P. Higgs, T. Attwood, 2013 .

Compositional Inheritance: Comparison of Self-assembly and Catalysis

P. Higgs, Meng Wu, 2008, Origins of Life and Evolution of Biospheres.

Information Resources for Genes and Proteins

P. Higgs, T. Attwood, 2013 .

Survival of RNA Replicators Is Much Easier in Protocells Than in Surface-Based, Spatial Systems

Vismay A. Shah, P. Higgs, Andrew S. Tupper, 2019, Life.

Conformation changes of a polyelectrolyte chain in a poor solvent

P. Higgs, É. Raphaël, 1991 .

Computer simulations of Template-Directed RNA Synthesis driven by temperature cycling in diverse sequence mixtures

P. Higgs, Pouyan Chamanian, 2022, PLoS Comput. Biol..

Comparison of the roles of nucleotide synthesis, polymerization, and recombination in the origin of autocatalytic sets of RNAs.

P. Higgs, Meng Wu, 2011, Astrobiology.

Planetary Systems and the Origins of Life

P. Higgs, J. Stone, R. Pudritz, 2007 .

Constraining the Time Interval for the Origin of Life on Earth.

P. Higgs, R. Pudritz, Ben K. D. Pearce, 2018, Astrobiology.

Monte-Carlo simulations of polymer crystallization in dilute solution

P. Higgs, Chi-Ming Chen, 1998 .

Theory of polyampholyte solutions

P. Higgs, J. Joanny, 1991 .

Medical management and monitoring of the hyperthyroid cat: a survey of UK general practitioners

P. Higgs, J. Murray, A. Hibbert, 2014, Journal of feline medicine and surgery.

Slip-links, hoops and tubes: tests of entanglement models of rubber elasticity

R. Gaylord, P. Higgs, 1990 .

Autocatalytic replication and homochirality in biopolymers: is homochirality a requirement of life or a result of it?

Sara I Walker, P. Higgs, S. Walker, 2012, Astrobiology.

Searching Sequence Databases

Teresa K. Attwood, Paul Higgs, P. Higgs, 2013 .

The Evolution of tRNA-Leu Genes in Animal Mitochondrial Genomes

M. Rattray, H. Jow, P. Higgs, 2003, Journal of Molecular Evolution.

OGRe: a relational database for comparative analysis of mitochondrial genomes

Daniel Jameson, Andrew P. Gibson, Paul G. Higgs, 2003, Nucleic Acids Res..

Theory of fission for two-component lipid vesicles

P. Higgs, F. MacKintosh, Chi-Ming Chen, 1997 .

Models of Sequence Evolution

P. Higgs, T. Attwood, 2013 .

Linking population genetics to phylogenetics

P. Higgs, 2008 .

Origin and evolution of gene families in Bacteria and Archaea

Hugh Merz, R. Collins, Paul G. Higgs, 2011, BMC Bioinformatics.

Scaling behavior of polyelectrolytes and polyampholytes: Simulation by an ensemble growth method

H. Orland, P. Higgs, 1991 .

Trapped Entanglements in Rubbers. A Unification of Models

P. Higgs, R. Ball, 1989 .

Coevolution of codon usage and tRNA genes leads to alternative stable states of biased codon usage.

P. Higgs, Paul G Higgs, Wenqi Ran, 2008, Molecular biology and evolution.

Identification of Conflicting Selective Effects on Highly Expressed Genes

P. Higgs, G. B. Golding, Weilong Hao, 2007, Evolutionary bioinformatics online.

Probabilistic Methods and Machine Learning

Teresa K. Attwood, Paul Higgs, P. Higgs, 2013 .

The Response of Amino Acid Frequencies to Directional Mutation Pressure in Mitochondrial Genome Sequences Is Related to the Physical Properties of the Amino Acids and to the Structure of the Genetic Code

P. Higgs, B. Tang, Daniela C. Urbina, 2005, Journal of Molecular Evolution.

A comprehensive analysis of mammalian mitochondrial genome base composition and improved phylogenetic methods.

Andrew P. Gibson, M. Rattray, P. Higgs, 2005, Molecular biology and evolution.

The growth of polymer crystals at the transition from extended chains to folded chains

P. Higgs, G. Ungar, 1994 .

Can the RNA World still function without cytidine?

P. Higgs, R. Pudritz, Andrew S. Tupper, 2019, Molecular biology and evolution.

Error thresholds for RNA replication in the presence of both point mutations and premature termination errors.

P. Higgs, Andrew S. Tupper, 2017, Journal of theoretical biology.

Co-operation between Polymerases and Nucleotide Synthetases in the RNA World

Yeeun Kim, Paul G. Higgs, P. Higgs, 2016, PLoS Comput. Biol..

The origin and spread of a cooperative replicase in a prebiotic chemical system.

Julie A. Shay, P. Higgs, Christopher Huynh, 2015, Journal of theoretical biology.

The origin of life is a spatially localized stochastic transition

P. Higgs, Meng Wu, 2012, Biology Direct.

The Importance of Stochastic Transitions for the Origin of Life

P. Higgs, Meng Wu, 2012, Origins of Life and Evolution of Biospheres.

Measurement of thyroxine and cortisol in canine and feline blood samples using two immunoassay analysers.

P. Higgs, K. Papasouliotis, M. Costa, 2014, The Journal of small animal practice.

Contributions of Speed and Accuracy to Translational Selection in Bacteria

Paul G. Higgs, P. Higgs, Wenqi Ran, 2012, PloS one.

The influence of anticodon-codon interactions and modified bases on codon usage bias in bacteria.

P. Higgs, Wenqi Ran, 2010, Molecular biology and evolution.

Estimating the Frequency of Horizontal Gene Transfer Using Phylogenetic Models of Gene Gain and Loss.

P. Higgs, Paul G Higgs, Seyed Alireza Zamani-Dahaj, 2016, Molecular biology and evolution.

RNA Sequence Evolution with Secondary Structure Constraints

Paul Higgs, David C. Hoyle, Nicholas J. Savill, 2000 .

Error thresholds and stationary mutant distributions in multi-locus diploid genetics models

Paul Higgs, P. Higgs, 1994 .

Creep measurements on gelatin gels.

P. Higgs, S. Ross‐Murphy, 1990, International journal of biological macromolecules.

The evolution of antibiotic production rate in a spatial model of bacterial competition

P. Higgs, S. Sengupta, Prateek Verma, 2018, bioRxiv.

A theoretical study of random segregation of minicircles in trypanosomatids

P. Higgs, N. Savill, 1999, Proceedings of the Royal Society of London. Series B: Biological Sciences.

When Is a Reaction Network a Metabolism? Criteria for Simple Metabolisms That Support Growth and Division of Protocells

P. Higgs, 2021, Life.

Rolling Circles as a Means of Encoding Genes in the RNA World

P. Higgs, Felipe Rivera-Madrinan, Katherine Di Iorio, 2022, Life.

Enhanced membrane rigidity in charged lamellar phases

P. Higgs, J. Joanny, 1990 .

Formation of gels and complexes by pairwise interacting polymers

P. Higgs, R. Ball, 1989 .

Sequence Alignment Algorithms

Teresa K. Attwood, Paul Higgs, P. Higgs, 2013 .

Comparison of tRNA and rRNA Phylogenies in Proteobacteria: Implications for the Frequency of Horizontal Gene Transfer

P. Higgs, B. Tang, Philippe Boisvert, 2004, q-bio/0404030.

Rolling-Circle and Strand-displacement Mechanisms for Non-enzymatic RNA Replication at the Time of the Origin of Life.

P. Higgs, Andrew S. Tupper, 2021, Journal of theoretical biology.

A Unified Model of Codon Reassignment in Alternative Genetic Codes

Supratim Sengupta, P. Higgs, S. Sengupta, 2004, Genetics.

Management and monitoring of hyperthyroid cats: a survey of Australian veterinarians

P. Higgs, R. Malik, A. Harvey, 2017, Journal of feline medicine and surgery.

Topological structure and interaction strengths in model food webs

Christopher Quince, Paul Higgs, Alan McKane, 2004, q-bio/0402014.

The Importance of Stochastic Transitions for the Origin of Life

P. Higgs, Meng Wu, 2012, Origins of Life and Evolution of Biospheres.

Evolution of Bipartite and Segmented Viruses from Monopartite Viruses

P. Higgs, Hyunjin Park, Saven Denha, 2023, Viruses.

Some ideas concerning the elasticity of biopolymer networks

P. Higgs, R. Ball, 1989 .

The Effect of Limited Diffusion and Wet–Dry Cycling on Reversible Polymerization Reactions: Implications for Prebiotic Synthesis of Nucleic Acids

P. Higgs, 2016, Life.

Chemical Evolution and the Evolutionary Definition of Life

P. Higgs, 2017, Journal of Molecular Evolution.

Polydisperse polymer networks : elasticity, orientational properties, and small angle neutron scattering

P. Higgs, R. Ball, 1988 .

Food web structure and the evolution of ecological communities

Christopher Quince, Alan J. McKane, Paul G. Higgs, 2001, nlin/0105057.

Redundant and non-functional guide RNA genes in Trypanosoma brucei are a consequence of multiple genes per minicircle.

P. Higgs, N. Savill, 2000, Gene.

Thermodynamics of RNA Folding: When is an RNA Molecule in Equilibrium?

Paul G. Higgs, Steven R. Morgan, P. Higgs, 1995, ECAL.

Dilution wave and negative-order crystallization kinetics of chain molecules.

P. Higgs, G. Ungar, D. D. De Silva, 2000, Physical Review Letters.

The dilution wave in polymer crystallization is described by Fisher’s reaction-diffusion equation

P. Higgs, G. Ungar, 2001 .

Natural selection at the class II major histocompatibility complex loci of mammals.

M. Nei, A. Hughes, P. Higgs, 1994, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

A four-column theory for the origin of the genetic code: tracing the evolutionary pathways that gave rise to an optimized code

P. Higgs, 2009, Biology direct.

DNA Microarrays and the 'omes

P. Higgs, T. Attwood, 2013 .

Planetary Systems and the Origins of Life

P. Higgs, J. Stone, J. Lunine, 2007 .

The evolution of antibiotic production rate in a spatial model of bacterial competition

P. Higgs, S. Sengupta, Prateek Verma, 2018, bioRxiv.

The RNA World: molecular cooperation at the origins of life

N. Lehman, P. Higgs, 2014, Nature Reviews Genetics.

Low-temperature properties of directed walks with random self interactions

B. Derrida, P. Higgs, 1994 .

A Model of Directed Walks with Random Self-Interactions

B. Derrida, P. Higgs, R. Griffiths, 1992 .