H. Pelham

发表

Use of peptide tagging to detect proteins expressed from cloned genes: deletion mapping functional domains of Drosophila hsp 70.

S. Munro, H. Pelham, 1984, The EMBO journal.

Transmembrane domain‐dependent sorting of proteins to the ER and plasma membrane in yeast

J. Rayner, H. Pelham, 1997, The EMBO journal.

Got1p and Sft2p: membrane proteins involved in traffic to the Golgi complex

H. Pelham, S. Conchon, X. Cao, 1999, The EMBO journal.

Arrestin-like proteins mediate ubiquitination and endocytosis of the yeast metal transporter Smf1

H. Pelham, J. Sullivan, E. Nikko, 2008, EMBO reports.

Arrestin-Mediated Endocytosis of Yeast Plasma Membrane Transporters

H. Pelham, E. Nikko, 2009, Traffic.

An efficient mRNA-dependent translation system from reticulocyte lysates.

H. Pelham, R. Jackson, 1976, European journal of biochemistry.

Translation of encephalomyocarditis virus RNA in vitro yields an active proteolytic processing enzyme.

H. Pelham, Hugh R. B. Pelham, 1978, European journal of biochemistry.

Control of the activity of WW‐HECT domain E3 ubiquitin ligases by NDFIP proteins

H. Pelham, T. Mund, 2009, EMBO reports.

Characteristics of a coupled cell-free transcription and translation system directed by vaccinia cores.

T. Hunt, H. Pelham, J. Sykes, 1978, European journal of biochemistry.

ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway

Jan C. Semenza, H. Pelham, J. Semenza, 1990, Cell.

Using sorting signals to retain proteins in endoplasmic reticulum.

H. Pelham, 2000, Methods in enzymology.

Two syntaxin homologues in the TGN/endosomal system of yeast

H. Pelham, B. Nichols, J. Holthuis, 1998, The EMBO journal.

Identification of Amino Acids in the Binding Pocket of the Human KDEL Receptor*

H. Pelham, A. Scheel, 1998, The Journal of Biological Chemistry.

Homotypic vacuolar fusion mediated by t- and v-SNAREs

H. Pelham, W. Wickner, B. Nichols, 1997, Nature.

A novel SNARE complex implicated in vesicle fusion with the endoplasmic reticulum

J. Rayner, H. Pelham, M. Lewis, 1997, The EMBO journal.

SNARE-Mediated Retrograde Traffic from the Golgi Complex to the Endoplasmic Reticulum

H. Pelham, M. Lewis, 1996, Cell.

A SNARE-like protein required for traffic through the Golgi complex

H. Pelham, D. Banfield, M. Lewis, 1995, Nature.

XIII. Yeast sequencing reports. SED6 is identical to ERG6, and encodes a putative methyltransferase required for ergosterol synthesis

H. Pelham, K. Hardwick, DY-----W--LRKLQDES--FKKS-VSRLFYSQV-----KRSLTSDSGMK GLVAGGKSKLFTPHlLNARKPEN4ETPSQTSQEATQ, 1994 .

Retrieval of HDEL proteins is required for growth of yeast cells

H. Pelham, F. Townsley, G. Frigerio, 1994, The Journal of cell biology.

A yeast homologue of a proteasome subunit.

H. Pelham, J. Semenza, 1991, DNA sequence : the journal of DNA sequencing and mapping.

Recycling of proteins between the endoplasmic reticulum and Golgi complex.

H. Pelham, 1991, Current opinion in cell biology.

The ERD2 gene determines the specificity of the luminal ER protein retention system

H. Pelham, D. Sweet, M. Lewis, 1990, Cell.

Control of protein exit from the endoplasmic reticulum.

H. Pelham, 1989, Annual review of cell biology.

Recycling of proteins from the Golgi compartment to the ER in yeast

H. Pelham, N. Dean, H. R. Pelham, 1990, The Journal of cell biology.

Membrane traffic: How do GGAs fit in with the adaptors?

H. Pelham, M. Black, 2001, Current Biology.

TMF is a golgin that binds Rab6 and influences Golgi morphology

H. Pelham, S. Siniossoglou, Y. Fridmann-Sirkis, 2004, BMC Cell Biology.

Substrate clustering potently regulates the activity of WW-HECT domain–containing ubiquitin ligases

H. Pelham, T. Mund, 2018, The Journal of Biological Chemistry.

Disinhibition of the HECT E3 ubiquitin ligase WWP2 by polymerized Dishevelled

H. Pelham, M. Gammons, M. Bienz, 2015, Open Biology.

SNAREs and the specificity of membrane fusion.

H. Pelham, 2001, Trends in cell biology.

Specific retrieval of the exocytic SNARE Snc1p from early yeast endosomes.

H. Pelham, H. Riezman, B. Nichols, 2000, Molecular biology of the cell.

Involvement of ATP in the nuclear and nucleolar functions of the 70 kd heat shock protein.

H. Pelham, M. Lewis, 1985, The EMBO journal.

Post-transcriptional control in the early mouse embryo

H. Pelham, P. Braude, G. Flach, 1979, Nature.

Evidence that luminal ER proteins are sorted from secreted proteins in a post‐ER compartment.

H. Pelham, 1988, The EMBO journal.

pH-dependent binding of KDEL to its receptor in vitro.

H. Pelham, D. Wilson, M. Lewis, 1993, The Journal of biological chemistry.

Ubiquitination of alpha-synuclein filaments by Nedd4 ligases

H. Pelham, M. Goedert, M. Masuda-Suzukake, 2018, PloS one.

An ecdysone response element in the Drosophila hsp27 promoter

H. Pelham, G. Riddihough, 1987, The EMBO journal.

Hsp70 accelerates the recovery of nucleolar morphology after heat shock.

H. Pelham, 1984, The EMBO journal.

Expression of a Drosophila heat shock protein in mammalian cells: transient association with nucleoli after heat shock.

H. Pelham, S. Lindquist, M. Lewis, 1984, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Sorting and retrieval between the endoplasmic reticulum and Golgi apparatus.

H. Pelham, 1995, Current opinion in cell biology.

Membrane Traffic: GGAs Sort Ubiquitin

H. Pelham, 2004, Current Biology.

A Selective Transport Route from Golgi to Late Endosomes That Requires the Yeast Gga Proteins

H. Pelham, M. Black, 2000, The Journal of cell biology.

Getting through the Golgi complex.

H. Pelham, Hugh R. B. Pelham, 1998, Trends in cell biology.

Purification and characterization of the human KDEL receptor.

H. Pelham, A. Scheel, 1996, Biochemistry.

A synthetic heat‐shock promoter element confers heat‐inducibility on the herpes simplex virus thymidine kinase gene.

H. Pelham, M. Bienz, 1982, The EMBO journal.

Translation of fragmented viral RNA in vitro

H. Pelham, 1979, FEBS letters.

Multiple targets for brefeldin A

H. Pelham, 1991, Cell.

A New Yeast Endosomal SNARE Related to Mammalian Syntaxin 8

H. Pelham, M. Lewis, 2002, Traffic.

SNAREs involved in traffic through the Golgi complex.

H. Pelham, D. Banfield, M. Lewis, 1995, Cold Spring Harbor symposia on quantitative biology.

The Sec1p homologue Vps45p binds to the syntaxin Tlg2p.

H. Pelham, B. Nichols, J. Holthuis, 1998, European journal of cell biology.

EJCB-Lecture. SNAREs and the organization of the secretory pathway.

H. Pelham, 1997, European journal of cell biology.

Localization of Sed5, a putative vesicle targeting molecule, to the cis- Golgi network involves both its transmembrane and cytoplasmic domains

H. Pelham, G. Warren, C. Rabouille, 1994, The Journal of cell biology.

The Croonian Lecture 1999. Intracellular membrane traffic: getting proteins sorted.

H. Pelham, 1999, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

SNAREs and the secretory pathway-lessons from yeast.

H. Pelham, 1999, Experimental cell research.

Cloning and expression of a gene encoding hsc73, the major hsp70‐like protein in unstressed rat cells.

P. Sorger, H. Pelham, 1987, The EMBO journal.

A Saccharomyces cerevisiae cyclophilin resident in the endoplasmic reticulum.

H. Pelham, G. Frigerio, 1993, Journal of molecular biology.

Structural Analysis of the Interaction Between the SNARE Tlg1 and Vps51

P. Evans, H. Pelham, H. Kent, 2006, Traffic.

The retention signal for soluble proteins of the endoplasmic reticulum.

H. Pelham, H R Pelham, 1990, Trends in biochemical sciences.

Toxin entry: how reversible is the secretory pathway?

H. Pelham, L. Roberts, J. Lord, 1992, Trends in cell biology.

Seventy‐kilodalton heat shock proteins and an additional component from reticulocyte lysate stimulate import of M13 procoat protein into microsomes.

H. Pelham, R. Zimmermann, M. Lewis, 1988, The EMBO journal.

A conserved heptapeptide restrains the activity of the yeast heat shock transcription factor.

H. Pelham, B. Jakobsen, H. R. Pelham, 1991, The EMBO journal.

Genes that allow yeast cells to grow in the absence of the HDEL receptor.

H. Pelham, J. Boothroyd, K. Hardwick, 1992, The EMBO journal.

Expression of a Drosophila heat‐shock protein in Xenopus oocytes: conserved and divergent regulatory signals.

H. Pelham, M. Bienz, 1982, The EMBO journal.

Polar transmembrane domains target proteins to the interior of the yeast vacuole.

H. Pelham, F. Reggiori, M. Black, 2000, Molecular biology of the cell.

The syntaxin Tlg1p mediates trafficking of chitin synthase III to polarized growth sites in yeast.

H. Pelham, B. Nichols, J. Holthuis, 1998, Molecular biology of the cell.

H. Pelham, D. D. Brown, W. Wormington, 1981, Proceedings of the National Academy of Sciences of the United States of America.

About turn for the COPs?

H. Pelham, 1994, Cell.

12 Functions of the hsp70 Protein Family: An Overview

H. Pelham, 1990 .

Is epimorphin involved in vesicular transport?

H. Pelham, 1993, Cell.

Mutational analysis of the human KDEL receptor: distinct structural requirements for Golgi retention, ligand binding and retrograde transport.

H. Pelham, F. Townsley, Duncan W. Wilson, 1993, The EMBO journal.

Bsd2 binds the ubiquitin ligase Rsp5 and mediates the ubiquitination of transmembrane proteins

H. Pelham, J. Valdez-Taubas, E. Hettema, 2004, The EMBO journal.

Inefficient Quality Control of Thermosensitive Proteins on the Plasma Membrane

H. Pelham, M. Lewis, 2009, PloS one.

Traffic through the Golgi apparatus

H. Pelham, 2001, The Journal of cell biology.

An hsp70-like protein in the ER: Identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein

S. Munro, H. Pelham, Sean Munro, 1986, Cell.

Maturation of Golgi cisternae directly observed.

H. Pelham, 2006, Trends in biochemical sciences.

Getting Stuck in the Golgi

H. Pelham, 2000, Traffic.

Synthesis and proteolytic processing of cowpea mosaic virus proteins in reticulocyte lysates.

H. Pelham, 1979, Virology.

Mechanisms of heat-shock gene activation in higher eukaryotes.

H. Pelham, M. Bienz, 1987, Advances in genetics.

Sorting of proteins into multivesicular bodies: ubiquitin‐dependent and ‐independent targeting

Fulvio Reggiori, H. Pelham, F. Reggiori, 2001, The EMBO journal.

A Reexamination of Messenger RNA Populations in the Preimplantation Mouse Embryo

H. Pelham, G. Schultz, P. Braude, 1981 .

A C-terminal signal prevents secretion of luminal ER proteins

S. Munro, H. Pelham, 1987, Cell.

Sorting of membrane proteins in the secretory pathway

S. Munro, H. Pelham, Sean Munro, 1993, Cell.

Heat shock factor is regulated differently in yeast and HeLa cells

Peter K. Sorger, Michael J. Lewis, P. Sorger, 1987, Nature.

A specific transcription factor that can bind either the 5S RNA gene or 5S RNA.

H. Pelham, D. D. Brown, 1980, Proceedings of the National Academy of Sciences of the United States of America.

ERD1, a yeast gene required for the retention of luminal endoplasmic reticulum proteins, affects glycoprotein processing in the Golgi apparatus.

H. Pelham, J. Semenza, K. Hardwick, 1990, The EMBO journal.

Heat shock and the sorting of luminal ER proteins.

H. Pelham, H. Pelham, Hugh R.B. Pelham, 1989, The EMBO journal.

Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation

P. Sorger, H. Pelham, 1988, Cell.

Purification and characterization of a heat‐shock element binding protein from yeast.

P. Sorger, H. Pelham, P. K. Sorger, 1987, The EMBO journal.

A regulatory upstream promoter element in the Drosophila Hsp 70 heat-shock gene

H. Pelham, 1982, Cell.

Constitutive binding of yeast heat shock factor to DNA in vivo

H. Pelham, B. Jakobsen, B. K. Jakobsen, 1988, Molecular and cellular biology.

Heat shock regulatory elements function as an inducible enhancer in the xenopus hsp70 gene and when linked to a heterologous promoter

H. Pelham, M. Bienz, 1986, Cell.

Activation of heat-shock genes in eukaryotes

H. Pelham, 1985 .

A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies

H. Pelham, F. Reggiori, 2002, Nature Cell Biology.

Properties and Uses of Heat Shock Promoters

H. Pelham, 1987 .

Transcription of Drosophila small hsp-tk hybrid genes is induced by heat shock and by ecdysterone in transfected Drosophila cells.

H. Pelham, E. Berger, C. Morganelli, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Sorting of soluble ER proteins in yeast.

H. Pelham, K. Hardwick, M. Lewis, 1988, The EMBO journal.

The dynamics of golgi protein traffic visualized in living yeast cells.

H. Pelham, S. Wooding, H. R. Pelham, 1998, Molecular biology of the cell.

Translation of tobacco rattle virus RNAs in vitro: four proteins from three RNAs.

H. Pelham, 1979, Virology.

Speculations on the functions of the major heat shock and glucose-regulated proteins

H. Pelham, 1986, Cell.

Association of an S1 nuclease-sensitive structure with short direct repeats 5′ of Drosophila heat shock genes

H. Pelham, A. Travers, H. A. Mace, 1983, Nature.

The use of promoter fusions in Drosophila genetics: Isolation of mutations affecting the heat shock response

H. Pelham, J. Parker-Thornburg, J. Bonner, 1984, Cell.

Immunological evidence that plants use both HDEL and KDEL for targeting proteins to the endoplasmic reticulum.

H. Pelham, C. Hawes, R. Napier, 1992, Journal of cell science.

A human homologue of the yeast HDEL receptor

H. Pelham, M. Lewis, 1990, Nature.

Mutation of the Adh gene of Drosophila melanogaster containing an internal tandem duplication.

M. Ashburner, H. Pelham, W. Chia, 1985, Journal of molecular biology.

Regulation of PTEN/Akt and MAP kinase signaling pathways by the ubiquitin ligase activators Ndfip1 and Ndfip2

H. Pelham, T. Mund, 2010, Proceedings of the National Academy of Sciences of the United States of America.

The KKXX signal mediates retrieval of membrane proteins from the Golgi to the ER in yeast.

H. Pelham, F. Townsley, 1994, European journal of cell biology.

A specific transcription factor that can bind either the 5 S RNA gene or 5 S RNA ( Xenopus oocytes / protection from DNase / ribonucleoprotein particles / developmental control of transcription )

H. Pelham, Donald D. Brown, 2022 .

Ric1p and Rgp1p form a complex that catalyses nucleotide exchange on Ypt6p

H. Pelham, S. Siniossoglou, Symeon Siniossoglou, 2000, The EMBO journal.

Transferrin receptor‐like proteins control the degradation of a yeast metal transporter

H. Pelham, M. Lewis, Helen E. M. Stimpson, 2006, The EMBO journal.

The secretion of proteins by cells

H. Pelham, 1992 .

Peptide and small molecule inhibitors of HECT-type ubiquitin ligases

H. Pelham, S. Maslen, T. Mund, 2014, Proceedings of the National Academy of Sciences.

Swf1‐dependent palmitoylation of the SNARE Tlg1 prevents its ubiquitination and degradation

H. Pelham, J. Valdez-Taubas, 2005, The EMBO journal.

The Debate about Transport in the Golgi—Two Sides of the Same Coin?

J. Rothman, H. Pelham, 2000, Cell.

Multiple interactions drive adaptor-mediated recruitment of the ubiquitin ligase rsp5 to membrane proteins in vivo and in vitro.

H. Pelham, J. Sullivan, E. Nikko, 2007, Molecular biology of the cell.

An effector of Ypt6p binds the SNARE Tlg1p and mediates selective fusion of vesicles with late Golgi membranes

H. Pelham, S. Siniossoglou, 2001, The EMBO journal.

Psr1p/Psr2p, Two Plasma Membrane Phosphatases with an Essential DXDX(T/V) Motif Required for Sodium Stress Response in Yeast*

H. Pelham, S. Siniossoglou, E. Hurt, 2000, The Journal of Biological Chemistry.

A Vacuolar v–t-SNARE Complex, the Predominant Form In Vivo and on Isolated Vacuoles, Is Disassembled and Activated for Docking and Fusion

H. Pelham, W. Wickner, B. Nichols, 1998, The Journal of cell biology.

Vps51p Links the VFT Complex to the SNARE Tlg1p*

H. Pelham, S. Siniossoglou, 2002, The Journal of Biological Chemistry.

SED5 encodes a 39-kD integral membrane protein required for vesicular transport between the ER and the Golgi complex

H. Pelham, K. Hardwick, K G Hardwick, 1992, The Journal of cell biology.

Slow Diffusion of Proteins in the Yeast Plasma Membrane Allows Polarity to Be Maintained by Endocytic Cycling

H. Pelham, J. Valdez-Taubas, Javier Valdez-Taubas, 2003, Current Biology.

SNAREs and membrane fusion in the Golgi apparatus.

H. Pelham, B. Nichols, 1998, Biochimica et biophysica acta.

The Saccharomyces cerevisiae SEC20 gene encodes a membrane glycoprotein which is sorted by the HDEL retrieval system.

H. Pelham, D.J. Sweet, D. J. Sweet, 1992, The EMBO journal.

Retromer and the sorting nexins Snx4/41/42 mediate distinct retrieval pathways from yeast endosomes

H. Pelham, E. Hettema, M. Lewis, 2003, The EMBO journal.

The TIP1 gene of Saccharomyces cerevisiae encodes an 80 kDa cytoplasmic protein that interacts with the cytoplasmic domain of Sec20p.

H. Pelham, D.J. Sweet, H. R. Pelham, 1993, The EMBO journal.

Ligand-induced redistribution of a human KDEL receptor from the Golgi complex to the endoplasmic reticulum

H. Pelham, M. Lewis, 1992, Cell.

The dynamic organisation of the secretory pathway.

H. Pelham, 1996, Cell structure and function.

Translation of cowpea mosaic virus RNA in a messenger dependent cell free system from rabbit reticulocytes

H. Pelham, E. J. Stuik, 1977 .

The glucose-regulated protein grp94 is related to heat shock protein hsp90.

P. Sorger, H. Pelham, 1987, Journal of molecular biology.

Insights from yeast endosomes.

H. Pelham, 2002, Current opinion in cell biology.

Changing the specificity of the sorting receptor for luminal endoplasmic reticulum proteins.

H. Pelham, J. Semenza, 1992, Journal of molecular biology.

Sequence of a second human KDEL receptor.

H. Pelham, M. Lewis, 1992, Journal of molecular biology.

A microsystem for the extraction and in-vitro translation of mouse embryo mRNA.

H. Pelham, P. Braude, 1979, Journal of reproduction and fertility.

Regulation of Dishevelled DEP domain swapping by conserved phosphorylation sites

H. Pelham, M. Gammons, M. Bienz, 2021, Proceedings of the National Academy of Sciences.

ERS1 a seven transmembrane domain protein from Saccharomyces cerevisiae.

H. Pelham, K. Hardwick, H. Pelham, 1990, Nucleic acids research.

Activation of the Drosophila hsp27 promoter by heat shock and by ecdysone involves independent and remote regulatory sequences

H. Pelham, G. Riddihough, 1986, The EMBO journal.

Heat inactivation of vaccinia virus particle-associated functions: properties of heated particles in vivo and in vitro

H. Pelham, G. Darby, J. Harper, 1978, Journal of virology.

Control of the activity of WW‐HECT domain E3 ubiquitin ligases by NDFIP proteins

H. Pelham, T. Mund, 2009, EMBO reports.