K. Rhodes

发表

Antibodies as Valuable Neuroscience Research Tools versus Reagents of Mass Distraction

K. Rhodes, J. Trimmer, 2006, The Journal of Neuroscience.

Localization of voltage-gated ion channels in mammalian brain.

K. Rhodes, J. Trimmer, 2004, Annual review of physiology.

Accessory Kv&bgr;1 Subunits Differentially Modulate the Functional Expression of Voltage-Gated K+ Channels in Mouse Ventricular Myocytes

J. Nerbonne, K. Rhodes, F. Aimond, 2005 .

The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease

K. Rhodes, S. Salloway, J. Sevigny, 2016, Nature.

beta-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: part 1. Design, synthesis, and lead identification.

K. Rhodes, B. Lagu, R. Scannevin, 2008, Bioorganic & medicinal chemistry letters.

β-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: Part 2. Optimization of α-amino substituents

K. Rhodes, B. Lagu, R. Scannevin, 2008 .

Modulation of A-type potassium channels by a family of calcium sensors

K. Rhodes, J. Trimmer, M. Bowlby, 2000, Nature.

Nicotine Dependence and Its Treatment

C. Heyser, T. Robbins, P. Svenningsson, 2010 .

Non-clinical Pharmacology of YTX-7739: a Clinical Stage Stearoyl-CoA Desaturase Inhibitor Being Developed for Parkinson’s Disease

Daniel F Tardiff, K. Rhodes, M. Lucas, 2022, Molecular Neurobiology.

Inhibiting Stearoyl-CoA Desaturase Ameliorates α-Synuclein Cytotoxicity.

Daniel F Tardiff, K. Rhodes, J. Piotrowski, 2018, Cell reports.

Comparison of acetylcholinesterase and choline acetyltransferase staining patterns in the optic tectum of the goldfish Carassius auratus. A histochemical and immunocytochemical analysis.

K. Rhodes, E. Mufson, S. Zottoli, 1987, Brain, behavior and evolution.

Localization of choline acetyltransferase to somata of posterior lateral line efferents in the goldfish

K. Rhodes, E. Mufson, P. Danielson, 1988, Brain Research.

Extension of the Thrombolytic Time Window With Minocycline in Experimental Stroke

K. Rhodes, E. Lo, Xiaoying Wang, 2008, Stroke.

Induction of matrix metalloproteinase, cytokines and chemokines in rat cortical astrocytes exposed to plasminogen activators

K. Rhodes, E. Lo, Xiaoying Wang, 2007, Neuroscience Letters.

Pharmacodynamics of Dimethyl Fumarate Are Tissue Specific and Involve NRF2-Dependent and -Independent Mechanisms.

K. Rhodes, P. Bista, M. Lukashev, 2016, Antioxidants & redox signaling.

Addendum: The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease

K. Rhodes, S. Salloway, J. Sevigny, 2017, Nature.

Death receptor 6 negatively regulates oligodendrocyte survival, maturation and myelination

K. Rhodes, Robert H Miller, S. Mi, 2011, Nature Medicine.

Patient-derived three-dimensional cortical neurospheres to model Parkinson’s disease

K. Rhodes, V. Khurana, W. Raja, 2021, bioRxiv.

Probing the Potassium Channel Kvβ1/Kv1.1 Interaction Using a Random Peptide Display Library

K. Rhodes, P. Spence, S. Lombardi, 1999, Annals of the New York Academy of Sciences.

Selective interaction of voltage-gated K+ channel beta-subunits with alpha-subunits.

K. Rhodes, J. Trimmer, K. Nakahira, 1996, The Journal of biological chemistry.

Structure-activity relationships of the Kvbeta1 inactivation domain and its putative receptor probed using peptide analogs of voltage-gated potassium channel alpha- and beta-subunits.

K. Rhodes, P. Spence, S. Lombardi, 1998, The Journal of biological chemistry.

Accessory Kvbeta1 subunits differentially modulate the functional expression of voltage-gated K+ channels in mouse ventricular myocytes.

J. Nerbonne, K. Rhodes, F. Aimond, 2005, Circulation research.

Erythropoietin for the Treatment of Acute Ischemic Stroke: Preclinical Rationale

K. Rhodes, L. Jolliffe, F. Farrell, 2006 .

Heteromultimer Formation in Native K+Channels

K. Rhodes, J. Trimmer, 2001 .

Association and Colocalization of the Kv (cid:98) 1 and Kv (cid:98) 2 (cid:98) -Subunits with Kv1 (cid:97) -Subunits in Mammalian Brain K (cid:49) Channel Complexes

K. Rhodes, J. Trimmer, M. Matos, 1997 .

Association and Colocalization of the Kvβ1 and Kvβ2 β-Subunits with Kv1 α-Subunits in Mammalian Brain K+Channel Complexes

K. Rhodes, J. Trimmer, M. Matos, 1997, The Journal of Neuroscience.

Accessory Kv (cid:1) 1 Subunits Differentially Modulate the Functional Expression of Voltage-Gated K (cid:2) Channels in Mouse Ventricular Myocytes Cellular Biology

J. Nerbonne, K. Rhodes, F. Aimond, 2005 .

[3H]Hemicholinium-3 binding in rabbit striatum: correspondence with patchy acetylcholinesterase staining and a method for quantifying striatal compartments

K. Rhodes, J. Joyce, J. Marshall, 1987, Brain Research.

A novel hinge system and incubation chamber for emulsion-coated coverslip autoradiography.

K. Rhodes, D. Rosene, K. Meiners, 1993, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

1-Hydroxy-2-pyridinone-based MMP inhibitors: synthesis and biological evaluation for the treatment of ischemic stroke.

K. Rhodes, R. Scannevin, Jianya Ma, 2008, Bioorganic & medicinal chemistry letters.

Light and electron microscopic analysis of KChIP and Kv4 localization in rat cerebellar granule cells

James S Trimmer, K. Rhodes, J. Trimmer, 2005, The Journal of comparative neurology.

KChIPs and Kv4 α Subunits as Integral Components of A-Type Potassium Channels in Mammalian Brain

K. Rhodes, J. Trimmer, Sharon L. Burke, 2004, The Journal of Neuroscience.

Two N-Terminal Domains of Kv4 K+ Channels Regulate Binding to and Modulation by KChIP1

K. Rhodes, P. Chanda, W. Somers, 2004, Neuron.

A Fundamental Role for KChIPs in Determining the Molecular Properties and Trafficking of Kv4.2 Potassium Channels*

K. Rhodes, J. Trimmer, J. Sweatt, 2003, Journal of Biological Chemistry.

Kvβ Subunit Oxidoreductase Activity and Kv1 Potassium Channel Trafficking*

K. Rhodes, J. Trimmer, B. Gong, 2002, The Journal of Biological Chemistry.

Identification of a trafficking determinant localized to the Kv1 potassium channel pore

K. Rhodes, J. Trimmer, R. Scannevin, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Experimental Localization of Kv1 Family Voltage-Gated K+ Channel α and β Subunits in Rat Hippocampal Formation

K. Rhodes, J. Trimmer, M. Monaghan, 2001, The Journal of Neuroscience.

βSubunits Promote K+ Channel Surface Expression through Effects Early in Biosynthesis

K. Rhodes, J. Trimmer, S. Hammond, 1996, Neuron.

Altered expression and localization of hippocampal A-type potassium channel subunits in the pilocarpine-induced model of temporal lobe epilepsy

K. Rhodes, J. Trimmer, H. Vacher, 2008, Neuroscience.

Antibody-based Validation of CNS Ion Channel Drug Targets

K. Rhodes, J. Trimmer, 2008, The Journal of general physiology.

Inhibitory effects of pimozide on cloned and native voltage-gated potassium channels.

K. Rhodes, Y. Lee, T. Argentieri, 2003, Brain research. Molecular brain research.

In vivo characterization of a dual adenosine A2A/A1 receptor antagonist in animal models of Parkinson's disease.

K. Rhodes, B. Shook, Xun Li, 2010, Journal of medicinal chemistry.

Substituted thieno[2,3-d]pyrimidines as adenosine A2A receptor antagonists.

M. T. Powell, K. Rhodes, B. Shook, 2013, Bioorganic & medicinal chemistry letters.

Methylene amine substituted arylindenopyrimidines as potent adenosine A(2A)/A(1) antagonists.

K. Rhodes, B. Shook, Xun Li, 2010, Bioorganic & medicinal chemistry letters.

Immunohistochemical localization of subtype 4a metabotropic glutamate receptors in the rat and mouse basal ganglia

K. Rhodes, A. Levey, D. Standaert, 1999, The Journal of comparative neurology.

Syntheses and in vitro evaluation of arylsulfone-based MMP inhibitors with heterocycle-derived zinc-binding groups (ZBGs).

K. Rhodes, R. Scannevin, Shyh-Ming Yang, 2008, Bioorganic & medicinal chemistry letters.

Selective Aggregation of Endogenous β‐Amyloid Peptide and Soluble Amyloid Precursor Protein in Cerebrospinal Fluid by Zinc

K. Rhodes, D. Tummolo, J. Jacobsen, 1997, Journal of neurochemistry.

Dimethyl Fumarate and Monoethyl Fumarate Exhibit Differential Effects on KEAP1, NRF2 Activation, and Glutathione Depletion In Vitro

K. Rhodes, R. Scannevin, P. Juhasz, 2015, PloS one.

Fumarates Promote Cytoprotection of Central Nervous System Cells against Oxidative Stress via the Nuclear Factor (Erythroid-Derived 2)-Like 2 Pathway

K. Rhodes, Masayuki Yamamoto, P. Bista, 2012, Journal of Pharmacology and Experimental Therapeutics.

Type I and type II Na+ channel α‐subunit polypeptides exhibit distinct spatial and temporal patterning, and association with auxiliary subunits in rat brain

K. Rhodes, J. Trimmer, B. Gong, 1999, The Journal of comparative neurology.

Remodelling inactivation gating of Kv4 channels by KChIP1, a small‐molecular‐weight calcium‐binding protein

K. Rhodes, M. Covarrubias, M. Bowlby, 2002, The Journal of physiology.

Elimination of fast inactivation in Kv4 A-type potassium channels by an auxiliary subunit domain

P. Distefano, K. Rhodes, M. Covarrubias, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Structure-Activity Relationships of the Kvβ1 Inactivation Domain and Its Putative Receptor Probed Using Peptide Analogs of Voltage-gated Potassium Channel α- and β-Subunits*

K. Rhodes, P. Spence, S. Lombardi, 1998, The Journal of Biological Chemistry.

Correction to: A Brain-Penetrant Stearoyl-CoA Desaturase Inhibitor Reverses α-Synuclein Toxicity

Daniel F Tardiff, K. Rhodes, D. Selkoe, 2022, Neurotherapeutics.

Design and characterization of optimized adenosine A₂A/A₁ receptor antagonists for the treatment of Parkinson's disease.

M. T. Powell, K. Rhodes, B. Shook, 2012, Journal of medicinal chemistry.

Discovery of 4-aminomethylphenylacetic acids as γ-secretase modulators via a scaffold design approach.

K. Rhodes, Lin Xu, D. Kocisko, 2011, Bioorganic & medicinal chemistry letters.

β-Amyloid Peptide-induced Apoptosis Regulated by a Novel Protein Containing a G Protein Activation Module*

B. Ozenberger, K. Rhodes, H. Sofia, 2001, The Journal of Biological Chemistry.

Voltage-Gated K+ Channel β Subunits: Expression and Distribution of Kvβ1 and Kvβ2 in Adult Rat Brain

K. Rhodes, J. Trimmer, N. Barrezueta, 1996, The Journal of Neuroscience.

Voltage-Gated K 1 Channel b Subunits : Expression and Distribution of Kv b 1 and Kv b 2 in Adult Rat Brain

K. Rhodes, J. Trimmer, N. Barrezueta, 1996 .

Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction

R. Huganir, K. Rhodes, K. Guckian, 2018, Scientific Reports.

Synapto‐depressive effects of amyloid beta require PICK1

R. Huganir, R. Malinow, K. Rhodes, 2014, The European journal of neuroscience.

JNJ-40255293, a novel adenosine A2A/A1 antagonist with efficacy in preclinical models of Parkinson's disease.

K. Rhodes, A. Megens, X. Langlois, 2014, ACS chemical neuroscience.

Immunolocalization of the Ca2+‐activated K+ channel Slo1 in axons and nerve terminals of mammalian brain and cultured neurons

K. Rhodes, J. Trimmer, R. Aldrich, 2006, The Journal of comparative neurology.

Overcoming the genotoxicity of a pyrrolidine substituted arylindenopyrimidine as a potent dual adenosine A(2A)/A(1) antagonist by minimizing bioactivation to an iminium ion reactive intermediate.

K. Rhodes, B. Shook, S. Rassnick, 2011, Chemical research in toxicology.

Identification of a cytoplasmic domain important in the polarized expression and clustering of the Kv2.1 K+ channel

K. Rhodes, J. Trimmer, H. Murakoshi, 1996, The Journal of cell biology.

Cryoprotection and Freezing Methods to Control Ice Crystal Artifact in Frozen Sections of Fixed and Unfixed Brain Tissue

Douglas L. Rosene, K. Rhodes, D. Rosene, 1990 .

Regulators of G-protein signaling 4: modulation of 5-HT1A-mediated neurotransmitter release in vivo

K. Rhodes, C. Beyer, Afshin Ghavami, 2004, Brain Research.

Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation

K. Rhodes, J. Spurlino, L. Kuo, 2017, The Journal of Biological Chemistry.

Role of Heteromultimers in the Generation of Myocardial Transient Outward K+ Currents

J. Nerbonne, K. Rhodes, J. Trimmer, 2002, Circulation research.

Kinetic Modulation of Kv4-Mediated A-Current by Arachidonic Acid Is Dependent on Potassium Channel Interacting Proteins

P. Distefano, K. Rhodes, M. Holmqvist, 2001, The Journal of Neuroscience.

Generation and characterization of subtype-specific monoclonal antibodies to K+ channel alpha- and beta-subunit polypeptides.

K. Rhodes, J. Trimmer, M. Matos, 1996, Neuropharmacology.

beta-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: part 2. Optimization of alpha-amino substituents.

K. Rhodes, B. Lagu, R. Scannevin, 2008, Bioorganic & medicinal chemistry letters.

Selective Interaction of Voltage-gated K Channel -Subunits with -Subunits (*)

K. Rhodes, J. Trimmer, K. Nakahira, 1996, The Journal of Biological Chemistry.

Choline acetyltransferase immunohistochemical staining in the goldfish (Carassius auratus) brain: Evidence that the Mauthner cell does not contain choline acetyltransferase

K. Rhodes, E. Mufson, S. Zottoli, 1986, Brain Research.

Neuroprotective Effects of BG-12 on Malonate-Induced Striatal Lesion Volume in Sprague-Dawley Rat Brain (P02.121)

K. Rhodes, T. Engber, R. Scannevin, 2012 .

Molecular KChIPs and Kv 4 Subunits as Integral Components of A-Type Potassium Channels in Mammalian Brain

K. Rhodes, J. Trimmer, Sharon L. Burke, 2004 .

KChIPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain.

K. Rhodes, J. Trimmer, Sharon L. Burke, 2004, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Discovery of BIIB042, a Potent, Selective, and Orally Bioavailable γ-Secretase Modulator.

K. Rhodes, Lin Xu, Tina Talreja, 2011, ACS medicinal chemistry letters.

Experimental localization of Kv1 family voltage-gated K+ channel alpha and beta subunits in rat hippocampal formation.

K. Rhodes, J. Trimmer, M. Monaghan, 2001, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Aminomethyl substituted thieno[2,3-d]pyrimidines as adenosine A2A receptor antagonists

K. Rhodes, B. Shook, R. Scannevin, 2011 .

Association and colocalization of the Kvbeta1 and Kvbeta2 beta-subunits with Kv1 alpha-subunits in mammalian brain K+ channel complexes.

K. Rhodes, J. Trimmer, M. Matos, 1997, The Journal of neuroscience : the official journal of the Society for Neuroscience.

BIIB042, a novel γ-secretase modulator, reduces amyloidogenic Aβ isoforms in primates and rodents and plaque pathology in a mouse model of Alzheimer's disease

K. Rhodes, Lin Xu, Tina Talreja, 2016, Neuropharmacology.

Neuroprotectants: Novel Approaches for Dementias

K. Rhodes, 2014 .

Extension of the Thrombolytic Time Window With Minocycline in Experimental Stroke

K. Rhodes, E. Lo, Xiaoying Wang, 2008, Stroke.

Fumarates Promote Cytoprotection of Central Nervous System Cells against Oxidative Stress via the Nuclear Factor (Erythroid-Derived 2)-Like 2 Pathway

K. Rhodes, Masayuki Yamamoto, P. Bista, 2012, Journal of Pharmacology and Experimental Therapeutics.

Voltage-gated K+ channel beta subunits: expression and distribution of Kv beta 1 and Kv beta 2 in adult rat brain.

K. Rhodes, J. Trimmer, N. Barrezueta, 1996, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Immunolocalization of the Ca2+‐activated K+ channel Slo1 in axons and nerve terminals of mammalian brain and cultured neurons

K. Rhodes, J. Trimmer, R. Aldrich, 2006, The Journal of comparative neurology.

“Disinactivation” of N-type Inactivation of Voltage-gated K Channels by an Erbstatin Analogue*

K. Rhodes, W. Childers, T. Argentieri, 2004, Journal of Biological Chemistry.

Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation

K. Rhodes, J. Spurlino, L. Kuo, 2017, The Journal of Biological Chemistry.

Optimization of arylindenopyrimidines as potent adenosine A(2A)/A(1) antagonists.

K. Rhodes, B. Shook, Xun Li, 2010, Bioorganic & medicinal chemistry letters.

Kv beta subunit oxidoreductase activity and Kv1 potassium channel trafficking.

K. Rhodes, J. Trimmer, B. Gong, 2002, The Journal of biological chemistry.

Results Expression of Kv 4 . 2 and Kv 4 . 3 in Adult Mouse Ventricles

J. Nerbonne, K. Rhodes, J. Trimmer, 2002 .