J. Cigudosa

J. Cigudosa, M. Calasanz, 2008, Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico.

Characterization of nonrandom chromosomal gains and losses in multiple myeloma by comparative genomic hybridization.

R S Chaganti, J. Cigudosa, S. Jhanwar, 1998, Blood.

Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases.

M. Paz, J. Cigudosa, M. Esteller, 2003, Human molecular genetics.

Novel Genomic Alterations and Mechanisms Associated With Tumor Progression in Oligodendroglioma and Mixed Oligoastrocytoma

Juan F. García, J. Cigudosa, D. Blesa, 2009, Journal of neuropathology and experimental neurology.

Adult acute myeloid leukemia cells do not express nonfunctional Ikaros isoforms

J. Cigudosa, M. Urioste, J. Benítez, 2002 .

Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma

J. Cigudosa, S. Rodríguez-Perales, G. Moreno-Bueno, 2003, The Journal of pathology.

BPTF is required for c-MYC transcriptional activity and in vivo tumorigenesis

F. Real, J. Cigudosa, V. J. S. Lobo, 2016, Nature Communications.

Chromosomal instability and phenotypic plasticity during the squamous–spindle carcinoma transition: association of a specific T(14;15) with malignant progression

J. Cigudosa, S. Rodríguez-Perales, M. Quintanilla, 2005, Oncogene.

Multicolor interphase cytogenetics for the study of plasma cell dyscrasias.

R. Siebert, J. Cigudosa, F. Prósper, 2007, Oncology reports.

Complex karyotype including 14q+ marker in a case of Waldenström's macroglobulinemia.

J. Cigudosa, M. Calasanz, J. Rifón, 1994, Cancer Genetics and Cytogenetics.

Identification of MNDA as a new marker for nodal marginal zone lymphoma

J. Cigudosa, L. Maestre, L. Sánchez-Verde, 2009, Leukemia.

ORIGINAL ARTICLE Identification of MNDA as a new marker for nodal marginal zone lymphoma

J. Cigudosa, L. Maestre, L. Sánchez-Verde, 2009 .

HCAD, closing the gap between breakpoints and genes

Alfonso Valencia, Joaquín Dopazo, Robert Hoffmann, 2004, Nucleic Acids Res..

Variability in the expression of polycomb proteins in different normal and tumoral tissues. A pilot study using tissue microarrays

J. Cigudosa, M. Vidal, M. Piris, 2006, Modern Pathology.

Gains, losses and complex karyotypes in myeloid disorders: a light at the end of the tunnel

J. Cigudosa, S. Álvarez, 2005, Hematological oncology.

Cytogenetic patterns in 384 northern-Spanish patients with haematological disorders.

J. Cigudosa, M. Calasanz, A. Gullón, 2004, Hereditas.

Simultaneous translocations of FGFR3/MMSET and CCND1 into two different IGH alleles in multiple myeloma: lack of concurrent activation of both proto-oncogenes.

R. Siebert, J. Cigudosa, F. Prósper, 2007, Cancer genetics and cytogenetics.

Detection of the first gross CDC73 germline deletion in an HPT‐JT syndrome family

J. Cigudosa, J. Suela, L. Sánchez, 2011, Genes, chromosomes & cancer.

Multicolor spectral karyotyping identifies new recurring breakpoints and translocations in multiple myeloma.

B. Klein, J. Cigudosa, S. Jhanwar, 1998, Blood.

DNA profiling by arrayCGH in acute myeloid leukemia and myelodysplastic syndromes

J. Cigudosa, J. Suela, S. Álvarez, 2007, Cytogenetic and Genome Research.

Retraction: Spontaneous human adult stem cell transformation.

J. Cigudosa, A. Bernad, J. García-Castro, 2010, Cancer research.

Cytogenetic analysis of 363 consecutively ascertained diffuse large B‐cell lymphomas

J. Cigudosa, S. Jhanwar, B. Johansson, 1999, Genes, chromosomes & cancer.

Frequent and Simultaneous Epigenetic Inactivation of TP53 Pathway Genes in Acute Lymphoblastic Leukemia

J. Cigudosa, F. Prósper, J. Martín-Subero, 2011, PloS one.

Identification of prefoldin amplification (1q23.3-q24.1) in bladder cancer using comparative genomic hybridization (CGH) arrays of urinary DNA

Joaquim Bellmunt, J. Cigudosa, F. Algaba, 2013, Journal of Translational Medicine.

New translocations in a case of atypical B-cell chronic lymphocytic leukemia: involvement of ATM, MLL, and TP53 genes.

J. Cigudosa, J. Benítez, E. Barragán, 2006, Cancer genetics and cytogenetics.

Exome sequencing reveals novel and recurrent mutations with clinical impact in blastic plasmacytoid dendritic cell neoplasm

J. Cigudosa, J. Hernández-Rivas, D. Pisano, 2014, Leukemia.

Chromosomal and gene amplification in diffuse large B-cell lymphoma.

J. Cigudosa, K. Offit, S. Jhanwar, 1998, Blood.

Duplication of 14q11.2 associates with short stature and mild mental retardation: A putative relation with quantitative trait loci

J. Cigudosa, D. Blesa, M. Roselló, 2007, American journal of medical genetics. Part A.

Molecular alterations associated with cyclin d1 overexpression in endometrial cancer

J. Cigudosa, Raquel Marcos, S. Rodríguez-Perales, 2004, International journal of cancer.

Cyclin D1 gene (CCND1) mutations in endometrial cancer

J. Cigudosa, S. Rodríguez-Perales, X. Matías-Guiu, 2003, Oncogene.

Centromere-localized breaks indicate the generation of DNA damage by the mitotic spindle

J. Cigudosa, C. Martínez-A, V. Trachana, 2010, Proceedings of the National Academy of Sciences.

Further definition of the proximal 19p13.3 microdeletion/microduplication syndrome and implication of PIAS4 as the major contributor

J. Cigudosa, L. Pérez-Jurado, P. Lapunzina, 2019, Clinical genetics.

Multiple oncogenic mutations and clonal relationship in spatially distinct benign human epidermal tumors

N. Malats, F. Real, J. Cigudosa, 2010, Proceedings of the National Academy of Sciences.

Are ER+PR+ and ER+PR- breast tumors genetically different? A CGH array study.

S. Serrano, J. Cigudosa, F. Solé, 2012, Cancer genetics.

Fluorescence in situ hybridization study of TEL / AML 1 fusion and other abnormalities involving TEL and AML 1 genes . Correlation with cytogenetic findings and prognostic value in children with acute lymphoblastic leukemia

J. Cigudosa, M. Urioste, C. Soto, 2022 .

Cytogenetic data in 41 patients with multiple myeloma. Karyotype and other clinical parameters.

J. Cigudosa, F. Prósper, M. Odero, 1994, Cancer genetics and cytogenetics.

Keratinocyte cell lines derived from severe generalized recessive Epidermolysis Bullosa patients carrying a highly recurrent COL7A1 homozygous mutation: models to assess cell and gene therapies in vitro and in vivo

J. Cigudosa, S. Llames, M. del Río, 2013, Experimental dermatology.

Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia.

Yi Zheng, Sara Alvarez, Michael Jansen, 2008, Cancer cell.

Fibroblast growth factor-2 increases the expression of neurogenic genes and promotes the migration and differentiation of neurons derived from transplanted neural stem/progenitor cells

J. Cigudosa, C. Vicario-Abejón, H. Méndez-Gómez, 2009, Neuroscience.

Splenic Follicular Lymphoma: Clinicopathologic Characteristics of a Series of 32 Cases

J. Cigudosa, M. Piris, J. Forteza, 2009, The American journal of surgical pathology.

Determining the profiles and parameters for gene amplification testing of growth factor receptors in lung cancer

J. Cigudosa, E. Brambilla, S. Lantuejoul, 2013, International journal of cancer.

Precision medicine needs pioneering clinical bioinformaticians

Alfonso Valencia, Joaquín Dopazo, Juan C. Cigudosa, 2019, Briefings Bioinform..

Identification of novel cytogenetic markers with prognostic significance in a series of 968 patients with primary myelodysplastic syndromes.

J. Cigudosa, F. Solé, M. Calasanz, 2005, Haematologica.

Response to lenalidomide in myelodysplastic syndromes with del(5q): influence of cytogenetics and mutations

L. Arenillas, J. Cigudosa, I. Marugán, 2013, British journal of haematology.

Myeloid neoplasms with der(1)t(1;19) may constitute a specific entity characterized by a cytogenetic biomarker and gene mutations involved in DNA methylation

J. Cigudosa, J. Suela, J. Menezes, 2014, Leukemia & lymphoma.

Further delineation of neuropsychiatric findings in Tatton-Brown-Rahman syndrome due to disease-causing variants in DNMT3A: seven new patients

Miguel Ángel Martínez, N. Rahman, Pablo I Alarcón, 2019, European Journal of Human Genetics.

Spanish Guidelines for the use of targeted deep sequencing in myelodysplastic syndromes and chronic myelomonocytic leukaemia

J. Cigudosa, F. Solé, J. Hernández-Rivas, 2019, British journal of haematology.

Abrogation of RUNX1 gene expression in de novo myelodysplastic syndrome with t(4;21)(q21;q22)

J. Cigudosa, B. Ferreira, X. Agirre, 2012, Haematologica.

About the origin and development of hereditary conventional renal cell carcinoma in a four-generation t(3;8)(p14.1;q24.23) family

J. Cigudosa, M. Urioste, J. Benítez, 2005, European Journal of Human Genetics.

Genomic imbalances and patterns of karyotypic variability in mantle-cell lymphoma cell lines.

E. Campo, J. Cigudosa, C. Caldas, 2006, Leukemia research.

Preclinical activity of LBH589 alone or in combination with chemotherapy in a xenogeneic mouse model of human acute lymphoblastic leukemia

J. Cigudosa, J. Martinez-Climent, F. Prósper, 2011, Leukemia.

Genetic Heterogeneity of Benign Thyroid Lesions

J. Cigudosa, O. Ferrer-Roca, J. A. Pérez-Gómez, 1998, Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology.

Genetic heterogeneity of benign thyroid

J. Cigudosa, E. P. omez, M. Esta, 1998 .

Stem Cell Reports Resource Efficient Recreation of t(11;22) EWSR1-FLI1 in Human Stem Cells Using CRISPR/Cas9

J. Cigudosa, S. Rodríguez-Perales, P. Menéndez, 2017 .

Cytogenetic risk stratification in chronic myelomonocytic leukemia

J. Cigudosa, F. Solé, M. Tormo, 2011, Haematologica.

A predictor based on the somatic genomic changes of the BRCA1/BRCA2 breast cancer tumors identifies the non-BRCA1/BRCA2 tumors with BRCA1 promoter hypermethylation.

Ana Osorio, Javier Benitez, Ramon Diaz-Uriarte, 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

Mechanisms of intracerebral lymphoma growth delineated in a syngeneic mouse model of central nervous system lymphoma.

S. Bens, R. Siebert, J. Cigudosa, 2013, Journal of neuropathology and experimental neurology.

ERBB2 and MYC alterations in BRCA1‐ and BRCA2‐associated cancers

J. Cigudosa, J. Benítez, J. Palacios, 2005, Genes, chromosomes & cancer.

Truncated RUNX1 protein generated by a novel t(1;21)(p32;q22) chromosomal translocation impairs the proliferation and differentiation of human hematopoietic progenitors

J. Cigudosa, J. Suela, S. Rodríguez-Perales, 2016, Oncogene.

Genomic and expression profiling identifies the B‐cell associated tyrosine kinase Syk as a possible therapeutic target in mantle cell lymphoma

Francesco Bertoni, Ivo Kwee, Giovanni Martinelli, 2006, British journal of haematology.

Identification of recurrent chromosomal breakpoints in multiple myeloma with complex karyotypes by combined G-banding, spectral karyotyping, and fluorescence in situ hybridization analyses.

R. Siebert, J. Cigudosa, F. Prósper, 2006, Cancer genetics and cytogenetics.

Deletion at 6q24.2–26 predicts longer survival of high‐grade serous epithelial ovarian cancer patients

J. Cigudosa, M. Urioste, J. Benítez, 2014, Molecular oncology.

De novo erythroleukemia chromosome features include multiple rearrangements, with special involvement of chromosomes 11 and 19

J. Cigudosa, M. Urioste, J. Benítez, 2003, Genes, chromosomes & cancer.

Characterization of a new human melanoma cell line with CD133 expression

J. Cigudosa, C. López-Ginés, A. Martínez-Romero, 2012, Human Cell.

Cytogenetic characterization reveals that the SAM-1 erythroid cell line is derived from K-562 cells.

J. Cigudosa, M. Urioste, J. Benítez, 2002, Blood.

Metastasizing anaplastic ependymoma in an adult. Chromosomal imbalances, metabolic and gene expression profiles

J. Cigudosa, D. Monleón, C. López-Ginés, 2009, Histopathology.

Release of Hypoacetylated and Trimethylated Histone H4 Is an Epigenetic Marker of Early Apoptosis*

L. Franco, M. Fraga, E. Ballestar, 2006, Journal of Biological Chemistry.

Spontaneous human adult stem cell transformation (Retracted article. See vol. 70, pg. 6682, 2010)

J. Cigudosa, A. Lloyd, A. Bernad, 2005 .

CSF3R T618I co-occurs with mutations of splicing and epigenetic genes and with a new PIM3 truncated fusion gene in chronic neutrophilic leukemia

A. Dopazo, J. Cigudosa, D. Pisano, 2013, Blood Cancer Journal.

Severe and recurrent episodes of bronchiolitis obliterans organising pneumonia associated with indolent CD4+ CD8+ T-cell leukaemia

J. Cigudosa, M. Bofill, J. Rodríguez-Sánchez, 2008, European Respiratory Journal.

A Competency Framework in Personalized Precision Medicine for Healthcare Professionals (Preprint)

J. Cigudosa, C. López-Otín, F. Martín-Sánchez, 2022, JMIR Medical Education.

Downregulation of specific miRNAs in hyperdiploid multiple myeloma mimics the oncogenic effect of IgH translocations occurring in the non-hyperdiploid subtype

J. Cigudosa, F. Prósper, R. Fonseca, 2013, Leukemia.

Extreme sensitivity to Yondelis® (Trabectedin, ET‐743) in low passaged sarcoma cell lines correlates with mutated p53

J. Cigudosa, M. Piris, M. Sánchez-Beato, 2007, Journal of cellular biochemistry.

Identifying occult maternal malignancies from 1.93 million pregnant women undergoing noninvasive prenatal screening tests

Tengyu Ma, Huanming Yang, Jian Wang, 2019, Genetics in Medicine.

A new case of acute nonlymphocytic leukemia (French-American-British subtype M1) with double minutes and c-MYC amplification.

J. Cigudosa, F. Solé, M. Salido, 2002, Cancer genetics and cytogenetics.

Nonendometrioid Carcinomas Frequently Overexpressed and Amplified in Nonendometrioid Endometrial Carcinoma : STK 15 Is Differential Gene Expression Profile in Endometrioid and Updated

J. Cigudosa, M. Andujar, S. Rodríguez-Perales, 2003 .

Double-staining chromogenic in situ hybridization as a useful alternative to split-signal fluorescence in situ hybridization in lymphoma diagnostics

A. Mottok, J. Cigudosa, L. Leoncini, 2010, Haematologica.

The molecular pathogenesis of the NUP98-HOXA9 fusion protein in acute myeloid leukemia

J. Cigudosa, J. Fitzgibbon, M. Calasanz, 2017, Leukemia.

Identification of Candidate Oncogenes in Acute Megakaryoblastic Leukemias with Gain of Chromosome 19.

J. Cigudosa, J. Benítez, D. Blesa, 2004 .

Complex karyotype in one patient with small cell variant of T-prolymphocytic leukemia. Analysis by G-banding and comparative genomic hybridization.

J. Cigudosa, M. Odero, M. Calasanz, 2001, Haematologica.

Double minute chromosomes and monosomy 7 in a lymphatic blast crisis of chronic myeloid leukemia.

J. Cigudosa, M. Calasanz, I. Ezpeleta, 1990, Cancer genetics and cytogenetics.

Multiple Myeloma by Comparative Genomic Hybridization Characterization of Nonrandom Chromosomal Gains and Losses in

J. Cigudosa, J. Michaeli, M. Odero, 2013 .

Recommendations for the use of microarrays in prenatal diagnosis

L. Armengol, J. Cigudosa, J. Suela, 2017 .

Identifying occult maternal malignancies from 1.93 million pregnant women undergoing noninvasive prenatal screening tests

Huanming Yang, Jian Wang, J. Cigudosa, 2019, Genetics in Medicine.

Neurofibromatosis 1, and Not TP53, seems to be the main target of chromosome 17 deletions in de novo acute myeloid leukemia.

Mercedes Robledo, Anna González-Neira, Sara Alvarez, 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via intraperitoneal: Additional effects of PTP1B inhibition

J. Cigudosa, P. Rada, Á. Valverde, 2023, Redox biology.

Multiple myeloma primary cells show a highly rearranged unbalanced genome with amplifications and homozygous deletions irrespective of the presence of immunoglobulin-related chromosome translocations.

J. Cigudosa, D. Blesa, F. Prósper, 2007, Haematologica.

t(2;5) Associated with a Histiocytic-Monocytic Neoplasm

J. Cigudosa, E. Matutes, A. Lemes, 2001, Leukemia & lymphoma.

Genomic Abnormalities Acquired in the Blastic Transformation of Splenic Marginal Zone B-cell Lymphoma

R. Siebert, J. Cigudosa, J. Martinez-Climent, 2003, Leukemia & lymphoma.

[Genetics applied to clinical practice in neurodevelopmental disorders].

J. Cigudosa, J. Suela, S. López-Martín, 2014, Revista de neurologia.

BCR‐ABL rearrangement and Variant’Philadelphia chromosome in de novo acute myelogenous leukaemia FAB subtype M1

J. Cigudosa, J. L. Carrasco, A. O. Gómez, 1995, British journal of haematology.