S. V. Nielsen

Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations

Maher M. Kassem, K. Lindorff-Larsen, S. V. Nielsen, 2017, PLoS genetics.

DVC1 (C1orf124) is a DNA damage–targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks

S. V. Nielsen, R. Hartmann-Petersen, N. Mailand, 2012, Nature Structural &Molecular Biology.

Understanding the Origins of Loss of Protein Function by Analyzing the Effects of Thousands of Variants on Activity and Abundance

K. E. Johansson, K. Lindorff-Larsen, S. V. Nielsen, 2020, bioRxiv.

Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome

K. Lindorff-Larsen, S. V. Nielsen, Amelie Stein, 2019, eLife.

Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome

K. Lindorff-Larsen, S. V. Nielsen, Amelie Stein, 2019, eLife.

Molecular Basis and Regulation of OTULIN-LUBAC Interaction

P. R. Elliott, S. V. Nielsen, N. Mailand, 2014, Molecular cell.

Disease-linked mutations cause exposure of a protein quality control degron.

K. Lindorff-Larsen, S. V. Nielsen, Amelie Stein, 2022, Structure.