Hyoung-Gon Lee

发表

Oxidative stress and mitochondrial dysfunction in Alzheimer's disease.

Xinglong Wang, Wenzhang Wang, Li Li, 2014, Biochimica et biophysica acta.

Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe?

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2003, Acta Neuropathologica.

The Role of Mitogen-Activated Protein Kinase Pathways in Alzheimer’s Disease

George Perry, Xiongwei Zhu, G. Perry, 2002, Neurosignals.

Role of metal dyshomeostasis in Alzheimer's disease.

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2011, Metallomics : integrated biometal science.

The X-chromosome instability phenotype in Alzheimer's disease: a clinical sign of accelerating aging?

Hyoung-Gon Lee, G. Casadesus, Mark A. Smith, 2009, Medical hypotheses.

Alzheimer's Disease and Vascular Deficiency: Lessons from Imaging Studies and Down Syndrome

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2012, Current gerontology and geriatrics research.

Autophagy in Alzheimer’s disease

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2010, Expert review of neurotherapeutics.

LASER LIGHT SCATTERING STUDIES OF BULK POLYMERS IN THE GLASS TRANSITION REGIME *

Hyoung-Gon Lee, R. Simha, A. Jamieson, 1981 .

Ectopic expression of phospho‐Smad2 in Alzheimer's disease: Uncoupling of the transforming growth factor‐β pathway?

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2006, Journal of neuroscience research.

Cell cycle aberrations in Alzheimer’s disease: a novel therapeutic opportunity

Hyoung-Gon Lee, G. Casadesus, Mark A. Smith, 2009, Expert review of neurotherapeutics.

Selective Pe-ripheral Taste Dysfunction in APP/PS1 Mutant Transgenic Mice.

Hyoung-Gon Lee, Lindsey J. Macpherson, R. M. Wood, 2020, Journal of Alzheimer's disease : JAD.

Neurofibrillary Tangle Formation as a Protective Response to Oxidative Stress in Alzheimer’s Disease

George Perry, Paula I. Moreira, Xiongwei Zhu, 2009 .

The Earliest Stage of Cognitive Impairment in Transition From Normal Aging to Alzheimer Disease Is Marked by Prominent RNA Oxidation in Vulnerable Neurons

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2012, Journal of neuropathology and experimental neurology.

Cellular prion protein is essential for oligomeric amyloid-β-induced neuronal cell death.

Xinglong Wang, G. Perry, Hyoung-Gon Lee, 2012, Human molecular genetics.

Novel therapeutics for Alzheimer's disease: an update.

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2010, Current opinion in drug discovery & development.

Cdk5 is a major regulator of p38 cascade: relevance to neurotoxicity in Alzheimer’s disease

Hyoung-Gon Lee, Mark A. Smith, K. Shah, 2010, Journal of neurochemistry.

Neuronal cell cycle re-entry markers are altered in the senescence accelerated mouse P8 (SAMP8).

Hyoung-Gon Lee, G. Casadesus, Mark A. Smith, 2012, Journal of Alzheimer's disease : JAD.

From aging to Alzheimer's disease: unveiling "the switch" with the senescence-accelerated mouse model (SAMP8).

G. Perry, Hyoung-Gon Lee, G. Casadesus, 2008, Journal of Alzheimer's disease : JAD.

BRG1 and BRM function antagonistically with c-MYC in adult cardiomyocytes to regulate conduction and contractility.

Hyoung-Gon Lee, D. Jeyaraj, B. Jensen, 2017, Journal of molecular and cellular cardiology.

Emerging evidence for the neuroprotective role of α-synuclein

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2006, Experimental Neurology.

Cell Cycle Re-Entry and Mitochondrial Defects in Myc-Mediated Hypertrophic Cardiomyopathy and Heart Failure

Hyoung-Gon Lee, Xiongwei Zhu, D. Felsher, 2009, PloS one.

The Application of Microarray Technology to Neuropathology: Cutting Edge Tool With Clinical Diagnostics Potential or Too Much Information?

Hyoung-Gon Lee, Mark A. Smith, A. Mcshea, 2006, Journal of neuropathology and experimental neurology.

Antigen–antibody dissociation in Alzheimer disease: a novel approach to diagnosis

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2008, Journal of neurochemistry.

Amyloid-β Vaccination: Testing the Amyloid Hypothesis? : Heads We Win, Tails You Lose!

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2006 .

Amyloid-Vaccination : Testing the Amyloid Hypothesis ?

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2006 .

Heads We Win, Tails You Lose!

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2006 .

A Comparative Efficacy of Propacetamol and Ketorolac in Postoperative Patient Controlled Analgesia

Hyoung-Gon Lee, Ji Hun Park, W. Kim, 2015, The Korean journal of pain.

Therapeutic opportunities in Alzheimer disease: one for all or all for one?

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2005, Current medicinal chemistry.

The Fallacy of Amyloid and Cognition in Alzheimer’s Disease

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2006, Drugs & aging.

P38 Activation Mediates Amyloid-β Cytotoxicity

Jiahuai Han, G. Perry, Hyoung-Gon Lee, 2005, Neurochemical Research.

Therapeutic potential of c-Myc inhibition in the treatment of hypertrophic cardiomyopathy

Hyoung-Gon Lee, Mark A. Smith, B. Hoit, 2011, Therapeutic advances in chronic disease.

Sequestration of p27 within the cytoplasm of cardiac myocytes in chronic ischemic heart disease: pathogenic implications for ischemic cardiomyopathy

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2006, AGE.

Sources and mechanisms of cytoplasmic oxidative damage in Alzheimer's disease.

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2004, Acta neurobiologiae experimentalis.

Oxidative stress and neuropsychiatric disorders in the life spectrum

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2017 .

Mitochondria: a therapeutic target in neurodegeneration.

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2010, Biochimica et biophysica acta.

CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson’s disease

P. Oettgen, G. Perry, Hyoung-Gon Lee, 2010, Journal of Neural Transmission.

Oxidative Adaptation in Aging and Alzheimer’s Disease: The Roles of Amyloid and Tau

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2005 .

Gclc deficiency in mouse CNS causes mitochondrial damage and neurodegeneration

Hyoung-Gon Lee, V. Monnier, W. Feng, 2017, Human molecular genetics.

Chronological primacy of oxidative stress in Alzheimer disease

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2005, Neurobiology of Aging.

Neuroprotective effect of cocoa flavonids on in vitro oxidative stress

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2009, European journal of nutrition.

Pathological phenotype in familial neurodegenerative disease: implications for families and therapeutic constructs

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2011 .

Bivalent ligand containing curcumin and cholesterol as fluorescence probe for Aβ plaques in Alzheimer's disease.

Hyoung-Gon Lee, Xiongwei Zhu, Kai Liu, 2012, ACS chemical neuroscience.

Oxidative stress and neuronal adaptation in Alzheimer disease: the role of SAPK pathways.

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2003, Antioxidants & redox signaling.

Amyloid-beta, BACE, and oxidative stress in Alzheimer's disease, a commentary on "The different aggregation state of beta-amyloid 1-42 mediates different effects on oxidative stress, neurodegeneration and BACE-1 expression".

G. Perry, Hyoung-Gon Lee, Xiongwei Zhu, 2006, Free radical biology & medicine.

Divalent metal transporter, iron, and Parkinson's disease: A pathological relationship

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2010, Cell Research.

Redox metals and oxidative abnormalities in human prion diseases

Hyoung-Gon Lee, B. Ghetti, H. Budka, 2005, Acta Neuropathologica.

Evidence for the novel expression of human kallikrein-related peptidase 3, prostate-specific antigen, in the brain.

Hyoung-Gon Lee, R. Castellani, Mark A. Smith, 2009, International journal of clinical and experimental pathology.

Lessons from the AN 1792 Alzheimer vaccine: lest we forget

Hyoung-Gon Lee, G. Münch, S. Robinson, 2004, Neurobiology of Aging.

All-trans retinoic acid as a novel therapeutic strategy for Alzheimer’s disease

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2009, Expert review of neurotherapeutics.

Correction: Individual Case Analysis of Postmortem Interval Time on Brain Tissue Preservation

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2016, PloS one.

Increases in the Proteins Modified by Malondialdehyde and Hydroxynonenal in the Hippocampus of Prion-Infected Mice

Hyoung-Gon Lee, Jae Il Kim, 2008 .

Accumulation of intraneuronal amyloid-β is common in normal brain.

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2014, Current Alzheimer research.

Neuroprotective Effects of The Amylin Analog, Pramlintide, on AD are associated with Oxidative Stress Regulation Mechanisms

Hyoung-Gon Lee, G. Casadesus, Jeffrey A. Blair, 2019 .

Untangling the Vascular Web from Alzheimer Disease and Oxidative Stress

Hyoung-Gon Lee, Xiongwei Zhu, A. Nunomura, 2012, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

Chronic oxidative stress causes increased tau phosphorylation in M17 neuroblastoma cells

Hyoung-Gon Lee, Xiongwei Zhu, M. Tabaton, 2010, Neuroscience Letters.

Direct and indirect roles of cyclin-dependent kinase 5 as an upstream regulator in the c-Jun NH2-terminal kinase cascade: relevance to neurotoxic insults in Alzheimer's disease.

Hyoung-Gon Lee, Mark A. Smith, K. Shah, 2009, Molecular biology of the cell.

Direct and Indirect Roles of Cyclin-dependent Kinase 5 as an Upstream Regulator in the c-Jun NH 2-Terminal Kinase Cascade : Relevance to Neurotoxic Insults in Alzheimer ’ s Disease

Hyoung-Gon Lee, Mark A. Smith, K. Shah, 2009 .

4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal.

Hyoung-Gon Lee, QUAN LIU, Mark A. Smith, 2005, Chemical research in toxicology.

The role of E2F1 in the development of hypertrophic cardiomyopathy.

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2011, International journal of clinical and experimental pathology.

Presenilin mutation: a deadly first hit in Alzheimer disease. A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice".

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2006, Free radical biology & medicine.

Cellular prion protein and Alzheimer disease

Hyoung-Gon Lee, R. Petersen, Wataru Kudo, 2013, Prion.

Memantine: "hypothesis testing" not "disease modifying" in Alzheimer's disease.

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2010, The American journal of pathology.

"Hypothesis Testing" not "Disease Modifying" in Alzheimer's Disease

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2010 .

Distinct chronology of neuronal cell cycle re-entry and tau pathology in the 3xTg-AD mouse model and Alzheimer's disease patients.

Hyoung-Gon Lee, Hyun-pil Lee, S. Siedlak, 2014, Journal of Alzheimer's disease : JAD.

Perspectives on the amyloid-beta cascade hypothesis.

Hyoung-Gon Lee, Xiongwei Zhu, J. Joseph, 2004, Journal of Alzheimer's disease : JAD.

Nuclear envelope dispersion triggered by deregulated Cdk5 precedes neuronal death

Hyoung-Gon Lee, Mark A. Smith, Soumitra S Ghosh, 2011, Molecular biology of the cell.

Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex

Wenzhang Wang, Hyoung-Gon Lee, Xiongwei Zhu, 2018, Molecular Neurodegeneration.

Differential Regulation of Glutamate Receptors in Alzheimer’s Disease

George Perry, Xiongwei Zhu, Hyoung-Gon Lee, 2002, Neurosignals.

Increased expression of CaM kinase II alpha in the brains of scrapie-infected mice

Hyoung-Gon Lee, J. Choi, R. Carp, 1999, Neuroscience Letters.

Antioxidant approaches for the treatment of Alzheimer’s disease

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2010, Expert review of neurotherapeutics.

Alzheimer disease, the two-hit hypothesis: an update.

George Perry, Xiongwei Zhu, Hyoung-Gon Lee, 2007, Biochimica et biophysica acta.

The cellular prion protein (PrPC) prevents apoptotic neuronal cell death and mitochondrial dysfunction induced by serum deprivation.

Hyoung-Gon Lee, J. Choi, R. Carp, 2004, Brain research. Molecular brain research.

Oxidative Stress and its Implications for Future Treatments and Management of Alzheimer Disease

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2010, International journal of biomedical science : IJBS.

Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer’s disease

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2012, Journal of Neurochemistry.

Mislocalization of CDK11/PITSLRE, a regulator of the G2/M phase of the cell cycle, in Alzheimer disease

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2011, Cellular & Molecular Biology Letters.

Reduced homocysteine-thiolactonase activity in Alzheimer's disease.

Hyoung-Gon Lee, Mark A. Smith, H. Jakubowski, 2010, Journal of Alzheimer's disease : JAD.

Neuroprotective properties of Bcl‐w in Alzheimer disease

Hyoung-Gon Lee, Xiongwei Zhu, M. Tabaton, 2004, Journal of neurochemistry.

Antioxidant protection and neurodegenerative disease: The role of amyloid-β and tau

George Perry, Hyoung-Gon Lee, R. Castellani, 2006 .

Will Preventing Protein Aggregates Live Up to Its Promise as Prophylaxis Against Neurodegenerative Diseases?

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2003, Brain pathology.

Oxidative Damage to RNA in Aging and Neurodegenerative Disorders

Hyoung-Gon Lee, Xiongwei Zhu, A. Nunomura, 2012, Neurotoxicity Research.

Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease

Hyoung-Gon Lee, Xiongwei Zhu, A. Takeda, 2009, Molecular Neurodegeneration.

Neurodegenerative processes in Alzheimer's disease: an overview of pathogenesis with strategic biomarker potential

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2011 .

Biomarkers in Alzheimer's disease: past, present and future.

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2010, Biomarkers in medicine.

Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2009, Neurochemistry International.

Neurogenesis in Human Hippocampus: Implications for Alzheimer Disease Pathogenesis

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2006, Neuroembryology and Aging.

Oncogenic parallels in Alzheimer disease

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2006 .

Neurogenesis in Alzheimer’s Disease

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2006 .

Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease

Hyoung-Gon Lee, R. Castellani, Mark A. Smith, 2009, Aging.

Consequences of RNA oxidation on protein synthesis rate and fidelity: implications for the pathophysiology of neuropsychiatric disorders.

Hyoung-Gon Lee, Xiongwei Zhu, A. Nunomura, 2017, Biochemical Society transactions.

Increased p27, an essential component of cell cycle control, in Alzheimer's disease

George Perry, Xiongwei Zhu, Hyoung-Gon Lee, 2003, Aging cell.

Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease

George Perry, Xiongwei Zhu, Hyoung-Gon Lee, 2009, The Journal of Neuroscience.

Oxidative stress signalling in Alzheimer's disease

George Perry, Xiongwei Zhu, Hyoung-Gon Lee, 2004, Brain Research.

Tau modifiers as therapeutic targets for Alzheimer's disease.

Hyoung-Gon Lee, Xiongwei Zhu, A. Nunomura, 2005, Biochimica et biophysica acta.

Oxidative Stress and Alzheimer Disease: Mechanisms and Therapeutic Opportunities

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2011 .

Neuronal failure in Alzheimer’s disease: a view through the oxidative stress looking-glass

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2014, Neuroscience Bulletin.

Oxidative Damage to RNA in Aging and Neurodegenerative Disorders

Hyoung-Gon Lee, Xiongwei Zhu, A. Nunomura, 2012, Neurotoxicity Research.

Down‐regulation of serum gonadotropins is as effective as estrogen replacement at improving menopause‐associated cognitive deficits

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2010, Journal of neurochemistry.

The sirtuin pathway in ageing and Alzheimer disease: mechanistic and therapeutic considerations

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2011, The Lancet Neurology.

Regulation of RhoA activity by the cellular prion protein

Hyoung-Gon Lee, Yong-Sun Kim, H. Choi, 2017, Cell Death & Disease.

Neuronal cell cycle re-entry mediates Alzheimer disease-type changes.

Hyoung-Gon Lee, G. Casadesus, Mark A. Smith, 2007, Biochimica et biophysica acta.

Machine-to-machine communication for agricultural systems: An XML-based auxiliary language to enhance semantic interoperability

Reza Ehsani, Hyoung-Gon Lee, Edmund W. Schuster, 2011 .

Neuropathology of Alzheimer disease: pathognomonic but not pathogenic

Hyoung-Gon Lee, Xiongwei Zhu, A. Nunomura, 2006, Acta Neuropathologica.

A Novel Origin for Granulovacuolar Degeneration in Aging and Alzheimer’s Disease: Parallels to Stress Granules

Hyoung-Gon Lee, Xiongwei Zhu, M. Tabaton, 2011, Laboratory Investigation.

Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex

Wenzhang Wang, Hyoung-Gon Lee, Xiongwei Zhu, 2018, Molecular Neurodegeneration.

Klf15 orchestrates circadian nitrogen homeostasis.

Saptarsi M. Haldar, F. Scheer, Hyoung-Gon Lee, 2012, Cell metabolism.

Tau phosphorylation in Alzheimer's disease: pathogen or protector?

Hyoung-Gon Lee, Xiongwei Zhu, A. Nunomura, 2005, Trends in molecular medicine.

Therapeutic potential of oxidative stress reduction in Alzheimer's disease

Hyoung-Gon Lee, Xiongwei Zhu, A. Nunomura, 2006 .

Nuclear and mitochondrial DNA oxidation in Alzheimer's disease

Hyoung-Gon Lee, Xiongwei Zhu, A. Nunomura, 2012, Free radical research.

Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream.

Hyoung-Gon Lee, Xiongwei Zhu, A. Nunomura, 2006, Science of aging knowledge environment : SAGE KE.

Neuroprotective Effects of the Amylin Analog, Pramlintide, on Alzheimer's Disease Are Associated with Oxidative Stress Regulation Mechanisms.

Hyoung-Gon Lee, G. Casadesus, Jeffrey A. Blair, 2019, Journal of Alzheimer's disease : JAD.

Neuroprotective effects of the amylin analogue pramlintide on Alzheimer's disease pathogenesis and cognition

Hyoung-Gon Lee, G. Casadesus, S. Arnold, 2014, Neurobiology of Aging.

The essential role of ERK in 4‐oxo‐2‐nonenal‐mediated cytotoxicity in SH‐SY5Y human neuroblastoma cells

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2009, Journal of neurochemistry.

Inhibition of Polo-like kinase 1 reduces beta-amyloid-induced neuronal cell death in Alzheimer's disease

Hyoung-Gon Lee, Xiaoqi Liu, B. Song, 2011, Aging.

R-α-lipoic acid as a potent agent of mitochondrial protection in alzheimer’s disease

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2012 .

Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease

George Perry, Xiongwei Zhu, Hyoung-Gon Lee, 2010, Redox report : communications in free radical research.

The Role of Mitogen-Activated Protein Kinase Pathways in Alzheimers Disease

Hyoung-Gon Lee, Xiongwei Zhu, A. Raina, 2002 .

Cdk5–Foxo3 axis: initially neuroprotective, eventually neurodegenerative in Alzheimer's disease models

Hyoung-Gon Lee, K. Shah, C. Shi, 2016, Journal of Cell Science.

Amyloid-β in Alzheimer Disease: The Null versus the Alternate Hypotheses

Hyoung-Gon Lee, Xiongwei Zhu, A. Nunomura, 2007, Journal of Pharmacology and Experimental Therapeutics.

Amyloid‐β in Alzheimer's disease: the horse or the cart? Pathogenic or protective?

Hyoung-Gon Lee, Xiongwei Zhu, R. Castellani, 2005 .

Perspectives on the Amyloid-β Cascade Hypothesis

Hyoung-Gon Lee, Xiongwei Zhu, J. Joseph, 2004 .

Pathological implications of cell cycle re-entry in Alzheimer disease

Xiongwei Zhu, Wataru Kudo, Hyoung-Gon Lee, 2010, Expert Reviews in Molecular Medicine.

Amyloid-β precursor protein promotes cell proliferation and motility of advanced breast cancer

Hyoung-Gon Lee, Hannah Gilmore, Seong-Jin Kim, 2014, BMC Cancer.

Insulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic Targets

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2009, Pharmaceuticals.

Staying connected: synapses in Alzheimer disease.

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2004, The American journal of pathology.

In Vitro Seeding Activity of Glycoform-Deficient Prions from Variably Protease-Sensitive Prionopathy and Familial CJD Associated with PrPV180I Mutation

Hyoung-Gon Lee, J. Langeveld, M. Moudjou, 2019, Molecular Neurobiology.

In Vitro Seeding Activity of Glycoform-Deficient Prions from Variably Protease-Sensitive Prionopathy and Familial CJD Associated with PrPV180I Mutation

Hyoung-Gon Lee, J. Langeveld, M. Moudjou, 2019, Molecular Neurobiology.

Cell cycle deregulation in the neurons of Alzheimer's disease.

Xiongwei Zhu, Jacek Z. Kubiak, Hyoung-Gon Lee, 2011, Results and problems in cell differentiation.

Increased expression of prion protein is associated with changes in dopamine metabolism and MAO activity in PC12 cells

Hyoung-Gon Lee, R. Carp, Yong-Sun Kim, 1999, Journal of Molecular Neuroscience.

Oxidative imbalance in alzheimer’s disease

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2007, Molecular Neurobiology.

Oxidative Stress and Neurodegeneration: An Inevitable Consequence of Aging? Implications for Therapy

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2010 .

Therapeutic opportunities in Alzheimer disease: Current concepts

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2009 .

The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2006, Mechanisms of Ageing and Development.

The sterol regulatory element‐binding protein 2 is dysregulated by tau alterations in Alzheimer disease

Wenzhang Wang, Hyoung-Gon Lee, Xiongwei Zhu, 2019, Brain pathology.

Molecular neuropathogenesis of Alzheimer's disease: an interaction model stressing the central role of oxidative stress.

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2012, Future neurology.

Curcumin/melatonin hybrid 5-(4-hydroxy-phenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide ameliorates AD-like pathology in the APP/PS1 mouse model.

Hyoung-Gon Lee, Xiongwei Zhu, P. Martínez-Martín, 2015, ACS chemical neuroscience.

Alzheimer Disease: Oxidative Stress and Compensatory Responses

Hyoung-Gon Lee, Xiongwei Zhu, A. Nunomura, 2009 .

Down‐regulation of serum gonadotropins but not estrogen replacement improves cognition in aged‐ovariectomized 3xTg AD female mice

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2014, Journal of neurochemistry.

SRPK2 Phosphorylates Tau and Mediates the Cognitive Defects in Alzheimer's Disease

Hyoung-Gon Lee, Xuekun Li, S. Yu, 2012, The Journal of Neuroscience.

Intraneuronal amyloid β accumulation and oxidative damage to nucleic acids in Alzheimer disease

Hyoung-Gon Lee, Xiongwei Zhu, A. Nunomura, 2010, Neurobiology of Disease.

Adiponectin-mimetic novel nonapeptide rescues aberrant neuronal metabolic-associated memory deficits in Alzheimer’s disease

Hyoung-Gon Lee, S. Réhman, B. Rutten, 2021, Molecular neurodegeneration.

Phosphorylated tau: toxic, protective, or none of the above.

Hyoung-Gon Lee, A. Nunomura, R. Castellani, 2008, Journal of Alzheimer's disease : JAD.

Thinking Outside the Box in Alzheimer Disease Treatment

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2011 .

Molecular Pathogenesis of Alzheimer’s Disease: Reductionist versus Expansionist Approaches

Hyoung-Gon Lee, Xiongwei Zhu, R. Castellani, 2009, International journal of molecular sciences.

Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees?

Hyoung-Gon Lee, Xiongwei Zhu, R. Castellani, 2007, Expert review of neurotherapeutics.

Alzheimer Disease Pathology As a Host Response

Hyoung-Gon Lee, Xiongwei Zhu, R. Castellani, 2008, Journal of neuropathology and experimental neurology.

Amyloid-β42 Interacts Mainly with Insoluble Prion Protein in the Alzheimer Brain*

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2011, The Journal of Biological Chemistry.

The Cell Cycle Regulator Phosphorylated Retinoblastoma Protein Is Associated With Tau Pathology in Several Tauopathies

Hyoung-Gon Lee, Xiongwei Zhu, M. Tabaton, 2011, Journal of neuropathology and experimental neurology.

Modification of amyloid-β1-42 fibril structure by methionine-35 oxidation.

Hyoung-Gon Lee, Mark A. Smith, M. Zagorski, 2013, Journal of Alzheimer's disease : JAD.

Aβ plaque-selective NIR fluorescence probe to differentiate Alzheimer's disease from tauopathies.

Hyoung-Gon Lee, Nagarjun Narayanaswamy, T. Govindaraju, 2017, Biosensors & bioelectronics.

Posttranslational modifications of α-tubulin in alzheimer disease

Hyoung-Gon Lee, Xiongwei Zhu, B. Su, 2015, Translational Neurodegeneration.

Current approaches in the treatment of Alzheimer's disease.

Hyoung-Gon Lee, R. Castellani, Mark A. Smith, 2008, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Individual Case Analysis of Postmortem Interval Time on Brain Tissue Preservation

Robert B. Petersen, Xiongwei Zhu, Hyoung-Gon Lee, 2016, PloS one.

BRCA1 May Modulate Neuronal Cell Cycle Re-Entry in Alzheimer Disease

Hyoung-Gon Lee, Xiongwei Zhu, A. Delacourte, 2007, International journal of medical sciences.

Distribution, levels, and activation of MEK1 in Alzheimer's disease

George Perry, Xiongwei Zhu, Hyoung-Gon Lee, 2003, Journal of neurochemistry.

Oxidative Stress Associated Signal Transduction Cascades in Alzheimer Disease

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2009 .

Signal transduction cascades associated with oxidative stress in Alzheimer's disease.

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2007, Journal of Alzheimer's disease : JAD.

Challenging the Amyloid Cascade Hypothesis: Senile Plaques and Amyloid‐β as Protective Adaptations to Alzheimer Disease

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2004, Annals of the New York Academy of Sciences.

A high performance finite capacitated MRP process using a computational grid

Jinwoo Park, Hyoung-Gon Lee, Namkyu Park, 2009 .

Retinoblastoma protein phosphorylation at multiple sites is associated with neurofibrillary pathology in Alzheimer disease.

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2008, International journal of clinical and experimental pathology.

Early induction of c-Myc is associated with neuronal cell death

Xiongwei Zhu, Wataru Kudo, Hyoung-Gon Lee, 2011, Neuroscience Letters.

Growth Factors , Cytokines , Cell Cycle Molecules The Neuronal Expression of MYC Causes a Neurodegenerative Phenotype in a Novel Transgenic Mouse

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2010 .

Mitogen‐ and stress‐activated protein kinase 1: Convergence of the ERK and p38 pathways in Alzheimer's disease

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2005, Journal of neuroscience research.

Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes

Hyoung-Gon Lee, Xiongwei Zhu, R. Castellani, 2008, AGE.

Pathology's new role: defining disease process and protective responses.

Hyoung-Gon Lee, Xiongwei Zhu, R. Castellani, 2008, International journal of clinical and experimental pathology.

Aberrant localization of importin α1 in hippocampal neurons in Alzheimer disease

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2006, Brain Research.

Transgenic Mouse Models of Alzheimer’s Disease: Behavioral Testing and Considerations

George Perry, Hyoung-Gon Lee, G. Casadesus, 2009 .

Causes versus effects: the increasing complexities of Alzheimer’s disease pathogenesis

Hyoung-Gon Lee, Xiongwei Zhu, R. Castellani, 2010, Expert review of neurotherapeutics.

The mitochondrial dynamics of Alzheimer's disease and Parkinson's disease offer important opportunities for therapeutic intervention.

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2011, Current pharmaceutical design.

Grid enabled MRP process improvement under distributed database environment

Jinwoo Park, Namkyu Park, Hyoung-Gon Lee, 2009, J. Syst. Softw..

Up-regulation of astrocyte metabotropic glutamate receptor 5 by amyloid-β peptide

Hyoung-Gon Lee, Mark A. Smith, M. O'Neill, 2009, Brain Research.

Treatment advances in Alzheimer's disease based on the oxidative stress model

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2009, F1000 medicine reports.

The therapeutic potential of metabolic hormones in the treatment of age-related cognitive decline and Alzheimer's disease.

Hyoung-Gon Lee, G. Casadesus, M. Pallàs, 2016, Nutrition research.

Cdk 5-FOXO 3 a Axis : Initially Neuroprotective , Eventually Neurodegenerative in Alzheimer ’ s Disease Models

Hyoung-Gon Lee, K. Shah, C. Shi, 2016 .

Amyloid beta: the alternate hypothesis.

Hyoung-Gon Lee, Xiongwei Zhu, A. Nunomura, 2006, Current Alzheimer research.

P38 activation mediates amyloid-beta cytotoxicity.

Hyoung-Gon Lee, George Perry, Xiongwei Zhu, 2005, Neurochemical research.

Neuroendocrinology‐based therapy for Alzheimer's disease

Hyoung-Gon Lee, G. Casadesus, Mark A. Smith, 2012, BioFactors.

Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer’s disease

Hyoung-Gon Lee, Xiongwei Zhu, Osamu Ogawa, 2004, Acta Neuropathologica.

The role of metabotropic glutamate receptors in Alzheimer's disease.

Hyoung-Gon Lee, Xiongwei Zhu, G. Casadesus, 2004, Acta neurobiologiae experimentalis.

Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance

Hyoung-Gon Lee, Xiongwei Zhu, G. Jicha, 2014, Journal of neurochemistry.

Early Induction of Oxidative Stress in Mouse Model of Alzheimer Disease with Reduced Mitochondrial Superoxide Dismutase Activity

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2012, PloS one.

Modulation of Hippocampal Plasticity and Cognitive Behavior by Short-term Blueberry Supplementation in Aged Rats

Hyoung-Gon Lee, Xiongwei Zhu, B. Shukitt-Hale, 2004, Nutritional neuroscience.

Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta.

George Perry, Xiongwei Zhu, Hyoung-Gon Lee, 2009, Journal of Alzheimer's disease : JAD.

The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival

S. Nakanishi, Hyoung-Gon Lee, Xiongwei Zhu, 2009, Brain Research.

Amyloid-beta in Alzheimer disease: the null versus the alternate hypotheses.

Hyoung-Gon Lee, Xiongwei Zhu, A. Nunomura, 2007, The Journal of pharmacology and experimental therapeutics.

Widespread distribution of reticulon‐3 in various neurodegenerative diseases

Hyoung-Gon Lee, Xiongwei Zhu, R. Castellani, 2010, Neuropathology : official journal of the Japanese Society of Neuropathology.

Amyloid-beta in Alzheimer's disease: the horse or the cart? Pathogenic or protective?

Hyoung-Gon Lee, Xiongwei Zhu, R. Castellani, 2005, International journal of experimental pathology.

Cellular prion protein is essential for oligomeric amyloid- b -induced neuronal cell death

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2012 .

Nonestrogen-based hormonal therapies for Alzheimer’s disease

Hyoung-Gon Lee, G. Casadesus, R. Castellani, 2008 .

Amyloids, Aggregates and Neuronal Inclusions: Good or Bad News for Neurons?

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2003 .

Efficient work measurement system of manufacturing cells using speech recognition and digital image processing technology

Jinwoo Park, Hyoung-Gon Lee, Jung-Chul Lee, 2006 .

Amyloid- _ and _ in Alzheimer’s Disease: What is the Neuropathology Trying to Tell Us?

Hyoung-Gon Lee, Xiongwei Zhu, A. Nunomura, 2005 .

disease:The roleofamyloid-f3and tau

Hyoung-Gon Lee, George Perry, 2006 .

Antioxidant protection and neurodegenerative disease: the role of amyloid-beta and tau.

Hyoung-Gon Lee, R. Castellani, Mark A. Smith, 2006, American journal of Alzheimer's disease and other dementias.

Dual Tasking and Memory Binding in Alzheimer’s Disease

S. Cappa, Hyoung-Gon Lee, G. Casadesus, 2011 .

BRG1 and BRM function antagonistically with c-MYC in adult cardiomyocytes to regulate conduction and contractility.

Hyoung-Gon Lee, D. Jeyaraj, B. Jensen, 2017, Journal of molecular and cellular cardiology.

Causes versus effects: the increasing complexities of Alzheimer’s disease pathogenesis

Hyoung-Gon Lee, Xiongwei Zhu, R. Castellani, 2010, Expert review of neurotherapeutics.

Cellular prion protein is essential for oligomeric amyloid-β-induced neuronal cell death.

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2012, Human molecular genetics.

Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease

Hyoung-Gon Lee, Xiongwei Zhu, R. Castellani, 2010, Redox report : communications in free radical research.

Neuroprotective effects of the amylin analogue pramlintide on Alzheimer's disease pathogenesis and cognition

Hyoung-Gon Lee, G. Casadesus, S. Arnold, 2014, Neurobiology of Aging.

Posttranslational modifications of α-tubulin in alzheimer disease

Hyoung-Gon Lee, Xiongwei Zhu, B. Su, 2015, Translational Neurodegeneration.

Klf15 orchestrates circadian nitrogen homeostasis.

Saptarsi M. Haldar, F. Scheer, Hyoung-Gon Lee, 2012, Cell metabolism.

The Open System for Master Production Scheduling: Information Technology for Semantic Connections between Data and Mathematical Models

Hyoung-Gon Lee, Edmund W. Schuster, E. W. Schuster, 2010 .

Pathological implications of cell cycle re-entry in Alzheimer disease

Hyoung-Gon Lee, Xiongwei Zhu, Mark A. Smith, 2010, Expert Reviews in Molecular Medicine.