C. Farber

C. Farber, E. Farber, G. Clines, 2020, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Genetic Variability affects the Skeletal Response to Unloading

C. Farber, V. Ferguson, H. Donahue, 2020, bioRxiv.

Genomic Modifiers of Natural Killer Cells, Immune Responsiveness and Lymphoid Tissue Remodeling Together Increase Host Resistance to Viral Infection

C. Farber, K. Tung, C. Rival, 2016, PLoS pathogens.

Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

Ryan D. Hernandez, May E. Montasser, Min A. Jhun, 2018, Nature Communications.

Bioenergetics during calvarial osteoblast differentiation reflect strain differences in bone mass.

C. Farber, C. Rosen, P. Le, 2014, Endocrinology.

Identification of Known and Novel Long Noncoding RNAs Potentially Responsible for the Effects of Bone Mineral Density (BMD) Genomewide Association Study (GWAS) Loci

C. Farber, L. Gerstenfeld, L. Mesner, 2022, Journal of Bone and Mineral Research.

Systems Genetics Analysis of Mouse Chondrocyte Differentiation

C. Farber, A. Lusis, B. Song, 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Differences in First-Trimester Maternal Metabolomic Profiles in Pregnancies Conceived From Fertility Treatments

C. Farber, K. Taylor, J. Rotter, 2018, The Journal of clinical endocrinology and metabolism.

Fine mapping reveals sex bias in QTL affecting growth, skeletal size and obesity-related traits on mouse chromosomes 2 and 11

C. Farber, J. Medrano, 2006 .

A high-resolution association mapping panel for the dissection of complex traits in mice.

Eleazar Eskin, Aiqing He, Isaac Neuhaus, 2010, Genome research.

Differential gene expression during placentation in pregnancies conceived with different fertility treatments compared with spontaneous pregnancies.

C. Farber, J. Rotter, S. Rich, 2019, Fertility and sterility.

Using global gene expression to dissect the genetics of osteoporosis

C. Farber, 2010 .

An Integrative Genetics Approach to Identify Candidate Genes Regulating BMD: Combining Linkage, Gene Expression, and Association

Eric E Schadt, Steve Horvath, Anatole Ghazalpour, 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

High-Resolution Mapping of Gene Expression Using Association in an Outbred Mouse Stock

Eleazar Eskin, Anatole Ghazalpour, Aldons J. Lusis, 2008, PLoS genetics.

Bicc1 is a genetic determinant of osteoblastogenesis and bone mineral density.

M. Budoff, C. Farber, M. Criqui, 2014, The Journal of clinical investigation.

The maternal-fetal interface of successful pregnancies and impact of fetal sex using single cell sequencing

C. Farber, H. Tseng, S. Rich, 2019, bioRxiv.

Single limb immobilization model for bone loss from unloading.

C. Farber, H. Donahue, J. Wayne, 2019, Journal of biomechanics.

Sexually dimorphic crosstalk at the maternal-fetal interface.

C. Farber, H. Tseng, S. Rich, 2020, The Journal of clinical endocrinology and metabolism.

Dissecting the Genetics of Osteoporosis using Systems Approaches.

C. Farber, Basel M. Al-Barghouthi, B. Al-Barghouthi, 2019, Trends in genetics : TIG.

Genetic determinants of bone mass and osteoporotic fracture

D. Kiel, C. Farber, Y. Hsu, 2020, Principles of Bone Biology.

Using “-omics” Data to Inform Genome-wide Association Studies (GWASs) in the Osteoporosis Field

C. Farber, Abdullah Abood, 2021, Current Osteoporosis Reports.

The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits

Brian J. Bennett, Christoph D. Rau, E. Eskin, 2016, Journal of Lipid Research.

Genetic analyses involving microsatellite ETH10 genotypes on bovine chromosome 5 and performance trait measures in Angus- and Brahman-influenced cattle.

C. Farber, J. Medrano, D. VanLeeuwen, 2011, Journal of animal science.

Genetic variability affects the response of skeletal muscle to disuse

C. Farber, S. Fulle, M. J. McClure, 2021, Journal of musculoskeletal & neuronal interactions.

Mouse Genome-Wide Association and Systems Genetics Identify Asxl2 As a Regulator of Bone Mineral Density and Osteoclastogenesis

Eleazar Eskin, Wei Zou, Emrah Kostem, 2011, PLoS genetics.

Glucagon regulates hepatic kisspeptin to impair insulin secretion.

C. Farber, S. Radovick, P. Mondal, 2014, Cell metabolism.

Genetics of Bone Fat and Energy Regulation

C. Farber, C. Ackert-Bicknell, C. Rosen, 2018 .

Transcriptome-wide Association Study and eQTL colocalization identify potentially causal genes responsible for bone mineral density GWAS associations

C. Farber, V. Ferguson, C. Ackert-Bicknell, 2021, bioRxiv.

Systems genetics in diversity outbred mice inform BMD GWAS and identify determinants of bone strength

Steven M. Tommasini, C. Farber, M. Bouxsein, 2021, Nature Communications.

Systems genetics analyses in Diversity Outbred mice inform human bone mineral density GWAS and identify Qsox1 as a novel determinant of bone strength

Steven M. Tommasini, C. Farber, M. Bouxsein, 2020, bioRxiv.

Bicc 1 is a genetic determinant of osteoblastogenesis and bone mineral density

M. Budoff, C. Farber, M. Criqui, 2014 .

Systems-Level Analysis of Genome-Wide Association Data

Charles R. Farber, C. Farber, 2013, G3: Genes | Genomes | Genetics.

Systems Genetic Analysis of Osteoblast-Lineage Cells

Brian J. Bennett, H. Kang, E. Eskin, 2012, PLoS genetics.

Identification of quantitative trait loci influencing skeletal architecture in mice: Emergence of Cdh11 as a primary candidate gene regulating femoral morphology

T. Garland, C. Farber, Ryan J. Buus, 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Gene networks associated with conditional fear in mice identified using a systems genetics approach

Eleazar Eskin, Andy Lin, Brian J. Bennett, 2011, BMC Systems Biology.

A computational approach for identification of core modules from a co-expression network and GWAS data

C. Farber, C. Ackert-Bicknell, Olivia L Sabik, 2021, STAR protocols.

Genome Scans for Transmission Ratio Distortion Regions in Mice

B. Yandell, E. Schadt, C. Farber, 2012, Genetics.

Genome-wide isolation of growth and obesity QTL using mouse speed congenic strains

C. Farber, J. Medrano, P. Corva, 2006, BMC Genomics.

Evaluation of a scalable approach to generate cell-type specific transcriptomic profiles of mesenchymal lineage cells

Steven M. Tommasini, C. Farber, S. Onengut-Gumuscu, 2022, bioRxiv.

Identification of a core module for bone mineral density through the integration of a co-expression network and GWAS data

C. Farber, C. Ackert-Bicknell, G. Calabrese, 2019, bioRxiv.

Fine Mapping Reveals Sex Bias in Quantitative Trait Loci Affecting Growth, Skeletal Size and Obesity-Related Traits on Mouse Chromosomes 2 and 11

C. Farber, J. Medrano, 2007, Genetics.

Genetic variability affects the skeletal response to immobilization in founder strains of the diversity outbred mouse population

C. Farber, V. Ferguson, Bhavya Senwar, 2021, Bone reports.

An Integration of Genome-Wide Association Study and Gene Expression Profiling to Prioritize the Discovery of Novel Susceptibility Loci for Osteoporosis-Related Traits

Nicole Soranzo, Eric E. Schadt, Serge Ferrari, 2010, PLoS genetics.

Bridging the splicing gap in human genetics with long-read RNA sequencing: finding the protein isoform drivers of disease.

Gloria M. Sheynkman, C. Farber, G. Sheynkman, 2022, Human molecular genetics.

RhoA determines lineage fate of mesenchymal stem cells by modulating CTGF–VEGF complex in extracellular matrix

C. Farber, Xu Cao, E. Farber, 2016, Nature Communications.

Dynamic changes in immune gene co-expression networks predict development of type 1 diabetes

P. Bingley, E. Bonifacio, J. Ilonen, 2021, Scientific Reports.

Overlapping mouse subcongenic strains successfully separate two linked body fat QTL on distal MMU 2

C. Farber, J. Medrano, C. Warden, 2015, BMC Genomics.

Whole-genome sequencing and deep imputation identifies non-coding variants near Engrailed-1 with large effects on bone mineral density and fracture

Matthew A. Hibbs, Stephen R. Williams, Warren A. Cheung, 2015 .

Whole-genome sequencing identifies non-coding variants near EN 1 with large effects on bone mineral density

Beth, Matthew A. Hibbs, Stephen R. Williams, 2014 .

Genetics of Osteoporosis

C. Farber, 2013 .

Future of Osteoporosis Genetics: Enhancing Genome‐Wide Association Studies

C. Farber, A. Lusis, 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Meta‐Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry

Daniel L. Koller, D. Kiel, A. Uitterlinden, 2019, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Dissection of a genetically complex cluster of growth and obesity QTLs on mouse chromosome 2 using subcongenic intercrosses

C. Farber, J. Medrano, 2007, Mammalian Genome.

Genetic analysis of osteoblast activity identifies Zbtb40 as a regulator of osteoblast activity and bone mass

C. Farber, C. Ackert-Bicknell, L. Mesner, 2019, bioRxiv.

Quantitative trait loci for bone mineral density and femoral morphology in an advanced intercross population of mice.

C. Farber, K. Hua, D. Pomp, 2013, Bone.

Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits

Brian J. Bennett, Eun Yong Kang, Christoph D. Rau, 2012, Mammalian Genome.

RNA-sequencing analysis of differential gene expression associated with arterial stiffness

C. Farber, E. Farber, S. Yun, 2020, Vascular.

Integrating GWAS and Co-expression Network Data Identifies Bone Mineral Density Genes SPTBN1 and MARK3 and an Osteoblast Functional Module.

Steven M. Tommasini, C. Farber, J. Stains, 2017, Cell systems.

Contemporary Approaches for Identifying Rare Bone Disease Causing Genes

C. Farber, T. Clemens, 2013, Bone Research.

Wnt-Lrp5 Signaling Regulates Fatty Acid Metabolism in the Osteoblast

C. Farber, T. Clemens, J. Ellis, 2015, Molecular and Cellular Biology.

A novel voluntary weightlifting model in mice promotes muscle adaptation and insulin sensitivity with simultaneous enhancement of autophagy and mTOR pathway

C. Farber, S. Rich, Joshua C. Drake, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Fentanyl-induced acute and conditioned behaviors in two inbred mouse lines: Potential role for Glyoxalase

C. Farber, L. Mesner, E. Rissman, 2021, Physiology & Behavior.

Genetic dissection of a major mouse obesity QTL (Carfhg2): integration of gene expression and causality modeling.

S. Horvath, J. Aten, C. Farber, 2009, Physiological genomics.

Segregation analysis of a sex ratio distortion locus in congenic mice.

C. Farber, J. Medrano, J. Casellas, 2010, The Journal of heredity.

A Role for MiR-93 in Cells In Vitro in the Absence of Injury and in Response to Hypoxia and Serum Starvation

C. Farber, B. Annex, Achillieas N. Pitsillides, 2013 .

A MicroRNA93–Interferon Regulatory Factor-9–Immunoresponsive Gene-1–Itaconic Acid Pathway Modulates M2-Like Macrophage Polarization to Revascularize Ischemic Muscle

C. Farber, T. Fox, B. Annex, 2017, Circulation.

MicroRNA-93 Controls Perfusion Recovery After Hindlimb Ischemia by Modulating Expression of Multiple Genes in the Cell Cycle Pathway

R. John Lye, Charles R. Farber, Ayotunde O. Dokun, 2013, Circulation.

Acute psychological stress, autonomic function, and arterial stiffness among women.

C. Farber, B. Teachman, Zhenqi Liu, 2019, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

Genome-Wide mRNA Expression Analysis of Acute Psychological Stress Responses.

C. Farber, B. Teachman, E. Farber, 2022, MEDICC review.

RACER: A data visualization strategy for exploring multiple genetic associations

C. Farber, Olivia L Sabik, 2018, bioRxiv.

Unraveling Inflammatory Responses using Systems Genetics and Gene-Environment Interactions in Macrophages

Brian J. Bennett, M. Pellegrini, A. Ghazalpour, 2012, Cell.

Identification of known and novel long non-coding RNAs potentially responsible for the effects of BMD GWAS loci

C. Farber, L. Gerstenfeld, L. Mesner, 2021, bioRxiv.

Sex differences in the late first trimester human placenta transcriptome

C. Farber, J. Rotter, S. Rich, 2018, Biology of Sex Differences.

Old Mice Have Less Transcriptional Activation But Similar Periosteal Cell Proliferation Compared to Young‐Adult Mice in Response to in vivo Mechanical Loading

Matthew J. Silva, C. Farber, I. Braenne, 2020, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

A Novel IFITM5 Mutation in Severe Atypical Osteogenesis Imperfecta Type VI Impairs Osteoblast Production of Pigment Epithelium‐Derived Factor

C. Farber, F. Glorieux, A. Quinlan, 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Identification of known and novel long non‐coding RNAs potentially responsible for the effects of BMD GWAS loci

C. Farber, L. Gerstenfeld, L. Mesner, 2022, Journal of Bone and Mineral Research.

Genomic variants within chromosome 14q32.32 regulate bone mass through MARK3 signaling in osteoblasts.

C. Farber, T. Clemens, L. Mesner, 2021, The Journal of clinical investigation.

Long-read proteogenomics to connect disease-associated sQTLs to the protein isoform effectors of disease

Gloria M. Sheynkman, C. Farber, L. Mesner, 2023, bioRxiv.

MicroRNA-30b Is Both Necessary and Sufficient for Interleukin-21 Receptor-Mediated Angiogenesis in Experimental Peripheral Arterial Disease

C. Farber, W. Leonard, R. Spolski, 2021, International journal of molecular sciences.

An APOO Pseudogene on Chromosome 5q Is Associated With Low-Density Lipoprotein Cholesterol Levels

Ivana V. Yang, Andrew D. Johnson, Ryan D. Hernandez, 2018, Circulation.

Mouse genome-wide association and systems genetics identifies Lhfp as a regulator of bone mass

G. Churchill, C. Farber, D. Gatti, 2018, bioRxiv.

Evidence of maternal QTL affecting growth and obesity in adult mice

C. Farber, J. Medrano, C. Warden, 2009, Mammalian Genome.

The RNA demethylase FTO is required for maintenance of bone mass and functions to protect osteoblasts from genotoxic damage

C. Farber, T. Clemens, D. Guttridge, 2019, Proceedings of the National Academy of Sciences.

A Systems-Level Understanding of Cardiovascular Disease through Networks

C. Farber, L. Mesner, 2016 .

Intramembranous bone regeneration in diversity outbred mice is heritable.

C. Farber, L. Mesner, G. Calabrese, 2022, Bone.

Infertility and treatments utilized have minimal effects on first trimester placenta DNA methylation and gene expression.

C. Farber, K. Taylor, J. Rotter, 2022, Fertility and sterility.

Exercise during pregnancy mitigates negative effects of parental obesity on metabolic function in adult mouse offspring.

C. Farber, J. Connelly, S. Rich, 2020, Journal of applied physiology.

MicroRNA-93 Controls Perfusion Recovery Following HindLimb Ischemia by Modulating Expression of Multiple Genes in the Cell Cycle Pathway

C. Farber, B. Annex, Achillieas N. Pitsillides, 2013 .

Identification of putative homology between horse microsatellite flanking sequences and cross-species ESTs, mRNAs and genomic sequences.

C. Farber, J. Medrano, 2004, Animal genetics.

Transcriptome-wide association study and eQTL colocalization identify potentially causal genes responsible for human bone mineral density GWAS associations

C. Farber, C. Ackert-Bicknell, D. Brautigan, 2022, eLife.

Overexpression of Scg5 increases enzymatic activity of PCSK2 and is inversely correlated with body weight in congenic mice

C. Farber, I. Lindberg, J. Medrano, 2008, BMC Genetics.

Genetics of Osteoporosis

C. Farber, 2013 .

Epigenome-wide association of liver methylation patterns and complex metabolic traits in mice.

Michael Q. Zhang, Brian J. Bennett, M. Pellegrini, 2015, Cell metabolism.

An Integrative Genetics Approach to Identify Candidate Genes Regulating BMD: Combining Linkage, Gene Expression, and Association

S. Horvath, E. Schadt, A. Ghazalpour, 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Identification of a gene module associated with BMD through the integration of network analysis and genome‐wide association data

C. Farber, 2010, Journal of Bone and Mineral Research.

Network Analysis Implicates Alpha-Synuclein (Snca) in the Regulation of Ovariectomy-Induced Bone Loss

C. Farber, C. Rosen, L. Mesner, 2016, Scientific Reports.

MicroRNA-93 Controls Perfusion Recovery After Hindlimb Ischemia by Modulating Expression of Multiple Genes in the Cell Cycle Pathway

C. Farber, B. Annex, Achillieas N. Pitsillides, 2013 .

Single‐Cell Transcriptomics of Bone Marrow Stromal Cells in Diversity Outbred Mice: A Model for Population‐Level scRNA‐Seq Studies

C. Farber, S. Onengut-Gumuscu, E. Farber, 2023, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Genetic variation influences the skeletal response to hindlimb unloading in the eight founder strains of the diversity outbred mouse population

C. Farber, Yue Zhang, Steven J. Meas, 2023, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Wnt-Lrp5 Signaling Regulates Fatty Acid Metabolism in the Osteoblast

C. Farber, T. Clemens, J. Ellis, 2015, Molecular and Cellular Biology.

Osteoblasts Generate Testosterone From DHEA and Activate Androgen Signaling in Prostate Cancer Cells

C. Farber, G. Clines, R. Auchus, 2021, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Genome Scans for Transmission Ratio Distortion Regions in Mice

B. Yandell, E. Schadt, C. Farber, 2012, Genetics.