P. Hougaard

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Survival models for heterogeneous populations derived from stable distributions

P. Hougaard, 1986 .

A class of multivanate failure time distributions

P. Hougaard, 1986 .

Analysis of overdispersed count data by mixtures of Poisson variables and Poisson processes.

G A Whitmore, G. A. Whitmore, M. L. Lee, 1997, Biometrics.

Frailty models for survival data

P. Hougaard, P Hougaard, 1995, Lifetime data analysis.

Life table methods for heterogeneous populations: Distributions describing the heterogeneity

Philip Hougaard, P. Hougaard, 1984 .

Risk factors for development of incipient and overt diabetic nephropathy in type 1 diabetic patients: a 10-year prospective observational study.

H. Parving, P. Hougaard, P. Rossing, 2002, Diabetes care.

Heterogeneity models of disease susceptibility, with application to diabetic nephropathy.

K Borch-Johnsen, P. Hougaard, K. Borch-Johnsen, 1994, Biometrics.

Insulin sensitivity index, acute insulin response, and glucose effectiveness in a population-based sample of 380 young healthy Caucasians. Analysis of the impact of gender, body fat, physical fitness, and life-style factors.

R N Bergman, K Borch-Johnsen, O. Pedersen, 1996, The Journal of clinical investigation.

Modelling multivariate survival

Philip Hougaard, P. Hougaard, 1987 .

Chemical Stability of Insulin. 2. Formation of Higher Molecular Weight Transformation Products During Storage of Pharmaceutical Preparations

P. Hougaard, S. Havelund, J. Brange, 1992, Pharmaceutical Research.

An Investigation of a Pair of Integral Equations for the Biharmonic Problem

P. Hougaard, S. Christiansen, 1978 .

Soluble, prolonged-acting insulin derivatives. III. Degree of protraction, crystallizability and chemical stability of insulins substituted in positions A21, B13, B23, B27 and B30.

P. Hougaard, K. Norris, J. Markussen, 1988, Protein engineering.

A Versatile Adaptive Dose-Finding Design Based on Multiple Endpoints

C. Pipper, P. Hougaard, C. Baayen, 2017 .

Significant reduction of the antiatherogenic effect of estrogen by long-term inhibition of nitric oxide synthesis in cholesterol-clamped rabbits.

P. Hougaard, N. Korsgaard, S. Stender, 1997, The Journal of clinical investigation.

[Saddlepoint Methods and Statistical Inference]: Comment

P. Hougaard, 1988 .

Ionization behavior of native and mutant insulins: pK perturbation of B13-Glu in aggregated species.

P. Hougaard, S. Havelund, N. Kaarsholm, 1990, Archives of biochemistry and biophysics.

Equivalent In Vivo Biological Activity of Insulin Analogues and Human Insulin Despite Different In Vitro Potencies

P. Hougaard, U. Ribel, A. Sorensen, 1990, Diabetes.

Receptor Binding and Tyrosine Kinase Activation by Insulin Analogues With Extreme Affinities Studied in Human Hepatoma HepG2 Cells

S. Gammeltoft, P. Hougaard, K. Drejer, 1991, Diabetes.

NovoSol Basal: pharmacokinetics of a novel soluble long acting insulin analogue.

A. Vaag, P. Hougaard, J. Markussen, 1989, BMJ.

Soluble, prolonged-acting insulin derivatives. II. Degree of protraction and crystallizability of insulins substituted in positions A17, B8, B13, B27 and B30.

P. Hougaard, U. Ribel, K. Norris, 1987, Protein engineering.

Is there a reasonable excuse for not providing post-operative analgesia when using animal models of peripheral neuropathic pain for research purposes?

P. Hougaard, L. Arvastson, S. Hestehave, 2017, PloS one.

Long-term risk of IDDM in first-degree relatives of patients with IDDM

P. Hougaard, F. Pociot, J. Nerup, 1994, Diabetologia.

Analyses of the rate of decline in stimulated c-peptide 12 months after diagnosis in children with newly diag-nosed type 1 diabetes. results from the Hvidoere study group on childhood diabetes

P. Hougaard, H. Mortensen, J. Thomsen, 2010 .

Relationship Between Blood Pressure and Urinary Albumin Excretion Rate in Young Danish Type 1 Diabetic Patients: Comparison to Non‐diabetic Children

H. Parving, P. Hougaard, H. Mortensen, 1994 .

Impact of IDDM2 on disease pathogenesis and progression in children with newly diagnosed type 1 diabetes: reduced insulin antibody titres and preserved beta cell function

M. Knip, S. Gammeltoft, P. Hougaard, 2005, Diabetologia.

Relation of circulating concentrations of chemokine receptor CCR5 ligands to C-peptide, proinsulin and HbA1c and disease progression in type 1 diabetes.

P. Hougaard, H. Kolb, H. Mortensen, 2008, Clinical immunology.

Shared frailty models

P. Hougaard, 2000 .

BLOOD PRESSURE IN CHILDREN WITH DIABETES MELLITUS

P. Hougaard, K. K. Ibsen, H. Rotne, 1983, Acta paediatrica Scandinavica.

Soluble, prolonged-acting insulin derivatives. I. Degree of protraction and crystallizability of insulins substituted in the termini of the B-chain.

P. Hougaard, U. Ribel, J. Markussen, 1987, Protein engineering.

New Definition for the Partial Remission Period in Children and Adolescents with T 1 D

P. Hougaard, H. Mortensen, T. Danne, 2009 .

Disease progression among 446 children with newly diagnosed type 1 diabetes located in Scandinavia, Europe, and North America during the last 27 yr

P. Hougaard, C. Beam, H. Mortensen, 2014, Pediatric Diabetes.

Meal-stimulated glucagon release is associated with postprandial blood glucose level and does not interfere with glycemic control in children and adolescents with new-onset type 1 diabetes.

J. Holst, P. Hougaard, H. Mortensen, 2007, The Journal of clinical endocrinology and metabolism.

Proinsulin, GLP‐1, and glucagon are associated with partial remission in children and adolescents with newly diagnosed type 1 diabetes

C. de Beaufort, P. Hougaard, H. Mortensen, 2012, Pediatric diabetes.

Modelling heterogeneity in survival data

P. Hougaard, 1991, Journal of Applied Probability.

Parent and health professional perspectives in the management of adolescents with diabetes: Development of assessment instruments for international studies

P. Hougaard, S. Greene, M. Fitzgerald, 2006, Quality of Life Research.

TRACKING OF BLOOD PRESSURES IN DIABETIC CHILDREN

P. Hougaard, K. K. Ibsen, H. Rotne, 1983, Acta paediatrica Scandinavica.

Increased mortality in a Danish cohort of young people with Type 1 diabetes mellitus followed for 24 years

P. Hougaard, F. Pociot, R. Broe, 2017, Diabetic medicine : a journal of the British Diabetic Association.

Prognostic significance of differential cell counts in non‐Hodgkin's lymphomas

P. Hougaard, H. Schultz, Jens Ersbøll, 1988, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

Multinational study in children and adolescents with newly diagnosed type 1 diabetes: association of age, ketoacidosis, HLA status, and autoantibodies on residual beta‐cell function and glycemic control 12 months after diagnosis

C. de Beaufort, P. Hougaard, H. Mortensen, 2009, Pediatric diabetes.

Epidemiological studies of diabetes mellitus in Denmark: 4. Clinical characteristics of insulin-treated diabetes

P. Hougaard, A. Green, 1983, Diabetologia.

Severe hypoglycaemia in 1076 adult patients with type 1 diabetes: influence of risk markers and selection

Philip Hougaard, P. Hougaard, S. Heller, 2004, Diabetes/metabolism research and reviews.

International Perspectives in Childhood and Adolescent Diabetes: A Review

P. Hougaard, H. Mortensen, H. Mortensen, 1997, Journal of pediatric endocrinology & metabolism : JPEM.

Choice of time scale for analysis of recurrent events data

P. Hougaard, 2022, Lifetime Data Analysis.

Parametrizations of Non‐Linear Models

Philip Hougaard, P. Hougaard, 1982 .

The Appropriateness of the Asymptotic Distribution in a Nonlinear Regression Model in Relation to Curvature

P. Hougaard, 1985 .

Treatment of nickel dermatitis with Antabuse® a double blind study

P. Hougaard, T. Menné, N. Veien, 1983, Contact dermatitis.

Analysis of Multivariate Survival Data

Philip Hougaard, P. Hougaard, 2001 .

Multi-state Models: A Review

P Hougaard, P. Hougaard, 1999, Lifetime data analysis.

Disease progression and search for monogenic diabetes among children with new onset type 1 diabetes negative for ICA, GAD- and IA-2 Antibodies

C. de Beaufort, M. Knip, F. Ashcroft, 2010, BMC endocrine disorders.

Prognostic significance of architectural patterns in non‐Hodgkin lymphomas

P. Hougaard, J. Ersbøll, H. Schultz, 2009 .

A Cox regression model for the relative mortality and its application to diabetes mellitus survival data.

N Keiding, K Borch-Johnsen, S Kreiner, 1985, Biometrics.

Prevalence of microalbuminuria, arterial hypertension, retinopathy, and neuropathy in patients with insulin dependent diabetes

H. Parving, P. Hougaard, E. Hommel, 1988, British medical journal.

Predictors of mortality in insulin dependent diabetes: 10 year observational follow up study

K Borch-Johnsen, H. Parving, P. Hougaard, 1996, BMJ.

Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes.

C. de Beaufort, J. Holst, S. Gammeltoft, 2007, European journal of endocrinology.

Co-localisation of the Kir 6 . 2 / SUR 1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes

J. Holst, S. Gammeltoft, P. Hougaard, 2007 .

Comparison of Metabolic Control in a Cross-Sectional Study of 2,873 Children and Adolescents With IDDM from 18 Countries

Philip Hougaard, P. Hougaard, H. Mortensen, 1997, Diabetes Care.

Albuminuria and Poor Glycemic Control Predict Mortality in NIDDM

H. Parving, P. Hougaard, K. Borch-Johnsen, 1995, Diabetes.

The PTPN22 C1858T gene variant is associated with proinsulin in new-onset type 1 diabetes

P. Hougaard, H. Mortensen, M. Vanelli, 2011, BMC Medical Genetics.

Circulating Levels of MicroRNA from Children with Newly Diagnosed Type 1 Diabetes and Healthy Controls: Evidence That miR-25 Associates to Residual Beta-Cell Function and Glycaemic Control during Disease Progression

P. Hougaard, F. Pociot, Chen-Yu Zhang, 2012, Experimental diabetes research.

Partial Remission Definition: Validation based on the insulin dose‐adjusted HbA1c (IDAA1C) in 129 Danish Children with New‐Onset Type 1 Diabetes

P. Hougaard, H. Mortensen, J. Petersen, 2014, Pediatric diabetes.

Comparison of the working formulation of non‐Hodgkin's lymphoma with the Rappaport, Kiel, and Lukes & Collins classifications. Translational value and prognostic significance based on review of 658 patients treated at a single institution

P. Hougaard, N. Nissen, K. Hou‐Jensen, 1985, Cancer.

Risk factors for development of incipient and overt diabetic nephropathy in patients with non-insulin dependent diabetes mellitus: prospective, observational study

H. Parving, P. Hougaard, K. Borch-Johnsen, 1997, BMJ.

Circadian variation in mitotic influx in a keratinized epithelium. The stathmokinetic technique used in vivo on the hamster cheek pouch epithelium and analyzed by periodic regression analysis.

N. Keiding, P. Hougaard, U. Møller, 1985, Virchows Archiv. B, Cell pathology including molecular pathology.

Fundamentals of Survival Data

P. Hougaard, P Hougaard, 1999, Biometrics.

Relationship between blood pressure and urinary albumin excretion rate in young Danish type 1 diabetic patients: comparison to non-diabetic children. Danish Study Group of Diabetes in Childhood.

H. Parving, P. Hougaard, H. Mortensen, 1994, Diabetic medicine : a journal of the British Diabetic Association.

Prevalence of micro- and macroalbuminuria, arterial hypertension, retinopathy and large vessel disease in European Type 2 (non-insulin-dependent) diabetic patients

A. Vaag, H. Parving, P. Hougaard, 1991, Diabetologia.

Lifespans of Twins: Does Zygosity Matter?

P. Hougaard, J. Kaprio, K. Christensen, 2019, Genes.

Syddansk Universitet Lifespans of Twins Does Zygosity Matter ?

P. Hougaard, J. Kaprio, K. Christensen, 2019 .

Lifespans of Twins Hjelmborg , Jacob 2019-02

P. Hougaard, J. Kaprio, K. Christensen, 2022 .

Activity of angiotensin-converting enzyme and risk of severe hypoglycaemia in type 1 diabetes mellitus

P. Hougaard, S. Pramming, B. Thorsteinsson, 2001, The Lancet.

Kernel function smoothing of insulin absorption kinetics

P. Hougaard, U. Ribel, A. Plum, 1989 .

Influence of Disease Duration on Circulating Levels of miRNAs in Children and Adolescents with New Onset Type 1 Diabetes

P. Hougaard, F. Pociot, H. Mortensen, 2018, Non-coding RNA.

Circulating microRNA levels predict residual beta cell function and glycaemic control in children with type 1 diabetes mellitus

P. Hougaard, F. Pociot, H. Mortensen, 2017, Diabetologia.

New Definition for the Partial Remission Period in Children and Adolescents With Type 1 Diabetes

C. de Beaufort, P. Hougaard, H. Mortensen, 2009, Diabetes Care.

Relative mortality of Type 1 (insulin-dependent) diabetes in Denmark: 1933–1981

N. Keiding, P. Hougaard, A. Green, 1985, Diabetologia.

35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts.

Thomas J. Smith, B. M. Rasmussen, V. C. Phan, 1999, Diabetologia.

Prediction of Severe Hypoglycaemia by Angiotensin-Converting Enzyme Activity and Genotype in Type 1 Diabetes

P. Hougaard, S. Pramming, B. Thorsteinsson, 2002, Diabetologia.

Dynamic evaluation of prognosis from time-dependent variables in acute myocardial infarction.

E. Gilpin, P. Hougaard, P Hougaard, 1983, The American journal of cardiology.

Variation within the PPARG gene is associated with residual beta‐cell function and glycemic control in children and adolescents during the first year of clinical type 1 diabetes

M. Knip, S. Gammeltoft, P. Hougaard, 2008, Pediatric diabetes.

Comparison of the Working Formulation of non-Hodgkin’s lymphoma with the Rappaport, the Kiel, and the Lukes-Collins Classifications. Correlations and prognostic value

P. Hougaard, N. Nissen, K. Hou‐Jensen, 1985 .

Good metabolic control is associated with better quality of life in 2,101 adolescents with type 1 diabetes.

P. Hougaard, S. Greene, H. McGee, 2001, Diabetes care.

Progression of microalbuminuria in type 1 diabetes: ten-year prospective observational study.

H. Parving, P. Hougaard, P. Rossing, 2005, Kidney international.

Statistical inference for shared frailty models

Philip Hougaard, P. Hougaard, 2000 .

Semiparametric Regression Models for Interval-Censored Survival Data, With and Without Frailty Effects

Philip Hougaard, P. Hougaard, 2008 .

Metabolic control and prevalence of microvascular complications in young Danish patients with Type 1 diabetes mellitus

P. Hougaard, A. Sjølie, B. Olsen, 1999, Diabetic medicine : a journal of the British Diabetic Association.

Plasma homocysteine concentration predicts mortality in non-insulin-dependent diabetic patients with and without albuminuria.

H. Parving, P. Hougaard, C. Stehouwer, 1999, Kidney international.

A 6-year nationwide cohort study of glycaemic control in young people with type 1 diabetes. Risk markers for the development of retinopathy, nephropathy and neuropathy. Danish Study Group of Diabetes in Childhood.

P. Hougaard, A. Sjølie, B. Olsen, 2000, Journal of diabetes and its complications.

40th EASD Annual Meeting of the European Association for the Study of Diabetes

B. M. Rasmussen, A. M. Foster, S. Bandinelli, 2004, Diabetologia.

Epidemiological studies of diabetes mellitus in Denmark: 5. Mortality and causes of death among insulin-treated diabetic patients

P. Hougaard, A. Green, 1984, Diabetologia.

Genetic variation and activity of the renin-angiotensin system and severe hypoglycemia in type 1 diabetes.

P. Hougaard, S. Pramming, B. Thorsteinsson, 2008, The American journal of medicine.

Nonlinear regression and curved exponential families. Improvement of the approximation to the asymptotic distribution

P. Hougaard, 1995 .

Fisher Information for Two Gamma Frailty Bivariate Weibull Models

P. Hougaard, Helgi Bjarnason, 2000, Lifetime data analysis.

Measuring the Similarities between the Lifetimes of Adult Danish Twins Born between 1881–1930

Philip Hougaard, P. Hougaard, N. Holm, 1992 .

Fitting a multivariate failure time distribution

P. Hougaard, P. Hougaard, 1989 .

Assessment of Dependence In the Life Times of Twins

Nancy Flournoy, Philip Hougaard, Karan P. Singh, 1992 .

Effect of insulin analogues on risk of severe hypoglycaemia in patients with type 1 diabetes prone to recurrent severe hypoglycaemia (HypoAna trial): a prospective, randomised, open-label, blinded-endpoint crossover trial.

H. Parving, P. Hougaard, L. Tarnow, 2014, The lancet. Diabetes & endocrinology.

Insulin management and metabolic control of Type 1 diabetes mellitus in childhood and adolescence in 18 countries

P. Hougaard, S. Greene, H. Mortensen, 1998, Diabetic medicine : a journal of the British Diabetic Association.

The significance of the prepubertal diabetes duration for the development of retinopathy and nephropathy in patients with type 1 diabetes.

P. Hougaard, A. Sjølie, B. Olsen, 2004, Journal of diabetes and its complications.

Improving the outcome for children and adolescents with type 1 diabetes: results of a changing service in Copenhagen

P. Hougaard, B. Olsen, H. Mortensen, 2000 .

Syddansk Universitet Influence of Disease Duration on Circulating Levels of miRNAs in Children and Adolescents with New Onset Type 1

P. Hougaard, F. Pociot, H. Mortensen, 2018 .

The length of hospitalization after acute myocardial infarction determined by risk calculation.

E. Gilpin, P. Hougaard, A. Pedersen, 1983, Circulation.

On a Moving Boundary Problem from Biomechanics

P. Hougaard, E. Hansen, P. Hougaard, 1974 .

Persistent differences among centers over 3 years in glycemic control and hypoglycemia in a study of 3,805 children and adolescents with type 1 diabetes from the Hvidøre Study Group.

P. Hougaard, S. Greene, H. Mortensen, 2001, Diabetes care.

Population based study of rates of multiple pregnancies in denmark, 1980-94

H. Parving, P. Hougaard, J. Salonen, 1997, BMJ.

Increased incidence of true type I diabetes acquired during pregnancy.

P. Hougaard, K. Buschard, C. Kühl, 1987, British medical journal.

Relationship between ZnT8Ab, the SLC30A8 gene and disease progression in children with newly diagnosed type 1 diabetes

C. de Beaufort, P. Hougaard, Å. Lernmark, 2011, Autoimmunity.

A Boundary Modification of Kernel Function Smoothing, with Application to Insulin Absorption Kinetics

P. Hougaard, 1988 .

Erratum to “Circulating Levels of MicroRNA from Children with Newly Diagnosed Type 1 Diabetes and Healthy Controls: Evidence That miR-25 Associates to Residual Beta-Cell Function and Glycaemic Control during Disease Progression”

P. Hougaard, F. Pociot, Chen-Yu Zhang, 2012, Experimental Diabetes Research.

Type 1 (insulin-dependent) diabetes mellitus diagnosed during pregnancy: a clinical and prognostic study

P. Hougaard, K. Buschard, C. Kühl, 1990, Diabetologia.

Significance of ventricular ectopic activity in the early recovery phase of acute myocardial infarction.

P. Hougaard, V. Rasmussen, J. F. Hansen, 2009, Acta medica Scandinavica.

Studentization and prediction problems in multivariate multiple regression

P. Hougaard, I. Guttman, 1985 .