K. Ulbrich

发表

Poly[N-(2-hydroxypropyl)methacrylamide] polymers diffuse in brain extracellular space with same tortuosity as small molecules.

C. Nicholson, E. Syková, S. Prokopová-Kubinová, 2001, Biophysical journal.

HPMA copolymers containing doxorubicin bound by a proteolytically or hydrolytically cleavable bond: comparison of biological properties in vitro.

K. Ulbrich, V. Šubr, M. Kovar, 2004, Journal of controlled release : official journal of the Controlled Release Society.

Polymer‐coated polyethylenimine/DNA complexes designed for triggered activation by intracellular reduction

K. Ulbrich, T. Etrych, L. Seymour, 2004, The journal of gene medicine.

Importance of lateral and steric stabilization of polyelectrolyte gene delivery vectors for extended systemic circulation.

Kenneth A Howard, Manfred Ogris, K. Ulbrich, 2002, Molecular therapy : the journal of the American Society of Gene Therapy.

Characterisation of the binding interaction between poly(L‐lysine) and DNA using the fluorescamine assay in the preparation of non‐viral gene delivery vectors

K. Ulbrich, T. Etrych, Martin L Read, 1999, FEBS letters.

Adenovirus retargeting and systemic delivery.

K. Ulbrich, D. Oupický, N. Green, 2003, Ernst Schering Research Foundation workshop.

A versatile system for receptor-mediated gene delivery permits increased entry of DNA into target cells, enhanced delivery to the nucleus and elevated rates of transgene expression

K. Ulbrich, V. Šubr, D. Blakey, 2000, Gene Therapy.

Treatment with HPMA copolymer-based doxorubicin conjugate containing human immunoglobulin induces long-lasting systemic anti-tumour immunity in mice

K. Ulbrich, V. Šubr, T. Mrkvan, 2006, Cancer Immunology, Immunotherapy.

Early Phase Tumor Accumulation of Macromolecules: A Great Difference in Clearance Rate between Tumor and Normal Tissues

Hiroshi Maeda, Ruth Duncan, K. Ulbrich, 1998, Japanese journal of cancer research : Gann.

Polymeric anticancer drugs with pH-controlled activation.

K. Ulbrich, V. Šubr, Karel Ulbrich, 2004, Advanced drug delivery reviews.

DNA delivery systems based on complexes of DNA with synthetic polycations and their copolymers.

K. Ulbrich, M. Wolfert, L. Seymour, 2000, Journal of controlled release : official journal of the Controlled Release Society.

Nanoparticles of the poly([ N -(2-hydroxypropyl)]methacrylamide)- b -poly[2-(diisopropylamino)ethyl methacrylate] diblock copolymer for pH-triggered release of paclitaxel

K. Ulbrich, C. Rodriguez-Emmenegger, P. Štěpánek, 2015 .

Ellipticine-aimed polymer-conjugated auger electron emitter: multistage organelle targeting approach.

K. Ulbrich, L. Kovář, B. Říhová, 2011, Bioconjugate chemistry.

Targeted Drug Delivery with Polymers and Magnetic Nanoparticles: Covalent and Noncovalent Approaches, Release Control, and Clinical Studies.

K. Ulbrich, V. Šubr, K. Holá, 2016, Chemical reviews.

Interaction of N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates with Human Liver Microsomal Cytochromes P450: Comparison with Free Doxorubicin

K. Ulbrich, P. Anzenbacher, T. Etrych, 2011, Drug Metabolism and Disposition.

Thermoresponsive, hydrolytically degradable polymer micelles intended for radionuclide delivery.

K. Ulbrich, K. Edwards, B. Říhová, 2009, Macromolecular bioscience.

Polymeric micellar pH-sensitive drug delivery system for doxorubicin.

K. Ulbrich, M. Hrubý, Č. Koňák, 2005, Journal of controlled release : official journal of the Controlled Release Society.

HPMA copolymer-doxorubicin conjugates: The effects of molecular weight and architecture on biodistribution and in vivo activity.

K. Ulbrich, V. Šubr, T. Etrych, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Extended plasma circulation time and decreased toxicity of polymer-coated adenovirus

K. Ulbrich, N. Green, V. Mautner, 2004, Gene Therapy.

Passive tumour targeting of polymer-coated adenovirus for cancer gene therapy

K. Ulbrich, V. Šubr, L. Seymour, 2007, Journal of drug targeting.

Incorporation of a laminin-derived peptide (SIKVAV) on polymer-modified adenovirus permits tumor-specific targeting via α6-integrins

K. Ulbrich, M. Stevenson, L. Seymour, 2007, Cancer Gene Therapy.

Polymeric drug-carriers containing doxorubicin and melanocyte-stimulating hormone: in vitro and in vivo evaluation against murine melanoma.

K. Ulbrich, R. Duncan, P. Kopec̆ková, 1993, Journal of drug targeting.

Intrinsically active nanobody-modified polymeric micelles for tumor-targeted combination therapy.

K. Ulbrich, W. Hennink, T. Etrych, 2013, Biomaterials.

Modification of pLL/DNA complexes with a multivalent hydrophilic polymer permits folate‐mediated targeting in vitro and prolonged plasma circulation in vivo

K. Ulbrich, L. Seymour, D. Oupický, 2002, The journal of gene medicine.

New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage: synthesis and preliminary in vitro and in vivo biological properties.

K. Ulbrich, T. Etrych, M. Jelínková, 2001, Journal of controlled release : official journal of the Controlled Release Society.

Combination chemotherapy using core-shell nanoparticles through the self-assembly of HPMA-based copolymers and degradable polyester.

K. Ulbrich, P. Štěpánek, T. Etrych, 2013, Journal of controlled release : official journal of the Controlled Release Society.

Comparison between linear and star-like HPMA conjugated pirarubicin (THP) in pharmacokinetics and antitumor activity in tumor bearing mice.

K. Ulbrich, H. Maeda, T. Etrych, 2015, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Biodegradation of biomedical polymers

Jindřich Kopeček, K. Ulbrich, J. Kopeček, 1983 .

Morphology of rat kidney and thymus after native and antibody-coupled cyclosporin A application (Reduced toxicity of targeted drug)

K. Ulbrich, B. Říhová, P. Rossmann, 2008, Folia Microbiologica.

Antibody-targeted cyclosporin A

K. Ulbrich, B. Říhová, A. Jegorov, 1992 .

Action of polymeric prodrugs based on N-(2-hydroxypropyl)-methacrylamide copolymers. II. Body distribution and T-cell accumulation of free and polymer-bound [125i]daunomycin

K. Ulbrich, V. Vetvicka, B. Říhová, 1989 .

Polymers containing enzymatically degradable bonds V. Hydrophilic polymers degradable by papain.

K. Ulbrich, J. Kopeček, E. I. Zacharieva, 1980, Biomaterials.

Polymers containing enzymatically degradable bonds, 4. Preliminary experiments in vivo

K. Ulbrich, J. Kopeček, P. Rejmanová, 1981 .

Doxorubicin release is not a prerequisite for the in vitro cytotoxicity of HPMA-based pharmaceuticals: in vitro effect of extra drug-free GlyPheLeuGly sequences.

K. Ulbrich, V. Šubr, T. Etrych, 2008, Journal of controlled release : official journal of the Controlled Release Society.

High-molecular weight star conjugates containing docetaxel with high anti-tumor activity and low systemic toxicity in vivo

K. Ulbrich, M. Kovar, T. Etrych, 2015 .

Biodegradable star HPMA polymer-drug conjugates: Biodegradability, distribution and anti-tumor efficacy.

K. Ulbrich, L. Kovář, T. Etrych, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Novel star HPMA-based polymer conjugates for passive targeting to solid tumors

K. Ulbrich, T. Etrych, B. Říhová, 2011, Journal of drug targeting.

HPMA-Anticancer Drug Conjugates

K. Ulbrich, V. Šubr, M. Kovar, 2010 .

Structural and chemical aspects of HPMA copolymers as drug carriers.

K. Ulbrich, V. Šubr, 2010, Advanced drug delivery reviews.

N-(2-Hydroxypropyl)methacrylamide-Based Polymer Conjugates with pH-Controlled Activation of Doxorubicin. I. New Synthesis, Physicochemical Characterization and Preliminary Biological Evaluation

K. Ulbrich, T. Etrych, T. Mrkvan, 2008 .

Poly(ethylene glycol)-Based Polymer Carrier of Doxorubicin Degradable by Both Enzymatic and Chemical Hydrolyses

K. Ulbrich, M. Pechar, A. Braunova, 2005 .

DEGRADATION BEHAVIOR OF POLY(ETHYLENE GLYCOL) DIBLOCK AND MULTIBLOCK POLYMERS WITH HYDROLYTICALLY DEGRADABLE ESTER LINKAGES

K. Ulbrich, M. Pechar, A. Braunova, 2004 .

Polymeric drugs based on conjugates of synthetic and natural macromolecules. II. Anti-cancer activity of antibody or (Fab')(2)-targeted conjugates and combined therapy with immunomodulators.

K. Ulbrich, V. Šubr, B. Říhová, 2000, Journal of controlled release : official journal of the Controlled Release Society.

Polymeric drugs based on conjugates of synthetic and natural macromolecules. I. Synthesis and physico-chemical characterisation.

K. Ulbrich, V. Šubr, B. Říhová, 2000, Journal of controlled release : official journal of the Controlled Release Society.

Poly[N-(2-Hydroypropyl)Methacrylamide] Conjugates of Bovine Seminal Ribonuclease. Synthesis, Physicochemical, and Preliminary Biological Evaluation

K. Ulbrich, V. Šubr, J. Matoušek, 2000 .

Targeting of human and mouse T-lymphocytes by monoclonal antibody-HPMA copolymer-doxorubicin conjugates directed against different T-cell surface antigens.

K. Ulbrich, V. Šubr, B. Říhová, 1998, Journal of controlled release : official journal of the Controlled Release Society.

Synthesis of N-(2-hydroxypropyl)methacrylamide copolymers with antimicrobial activity.

K. Ulbrich, J. Kopeček, M. V. Solovskij, 1983, Biomaterials.

Effect of the chemical structure of N- (2- hydroxypropyl) methacrylajnide copolymers on their ability to induce antibody formation in inbred strains of mice

K. Ulbrich, B. Říhová, M. Pospíšil, 1984 .

Immunogenicity of N‐(2‐hydroxypropyl) methacrylamide copolymers

K. Ulbrich, B. Říhová, J. Kopeček, 1985 .

In vivo and in vitro immunogenicity of water-soluble haptenated copolymers for mouse and human lymphocytes

K. Ulbrich, J. Kopeček, F. Rypáček, 1985 .

Poly(ethylene glycol)s containing enzymatically degradable bonds

K. Ulbrich, J. Kopeček, J. Strohalm, 1986 .

Solution properties of drug carriers based on poly[N‐(2‐hydroxypropyl)methacrylamide] containing biodegradable bonds

K. Ulbrich, J. Kopeček, Č. Koňák, 1987 .

Polymer-bound derivatives of sarcolysin and their antitumour activity against mouse and human leukaemia in vitro

K. Ulbrich, J. Kopeček, R. Duncan, 1987 .

Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. 3. Evaluation of adriamycin conjugates against mouse leukaemia L1210 in vivo

K. Ulbrich, J. Kopeček, R. Duncan, 1989 .

Biocompatibility of N-(2-hydroxypropyl) methacrylamide copolymers containing adriamycin. Immunogenicity, and effect on haematopoietic stem cells in bone marrow in vivo and mouse splenocytes and human peripheral blood lymphocytes in vitro.

K. Ulbrich, V. Vetvicka, B. Říhová, 1989, Biomaterials.

Action of polymeric prodrugs based on N-(2-hydroxypropyl)meth- acrylamide copolymers. I. Suppression of the antibody response and proliferation of mouse splenocytes in vitro

K. Ulbrich, V. Vetvicka, B. Říhová, 1989 .

Selectivity of Antibody-Targeted Anthracycline Antibiotics on T Lymphocytes

K. Ulbrich, B. Říhová, J. Strohalm, 1990 .

Targetable photoactivatable drugs, 2. Synthesis of N‐(2‐hydroxypropyl)methacrylamide copolymeranti‐thy 1.2 antibody‐chlorin e6 conjugates and a preliminary study of their photodynamic effect on mouse splenocytes in vitro

N. L. Krinick, K. Ulbrich, B. Říhová, 1990 .

The pharmacokinetics of polymer-bound adriamycin.

K. Ulbrich, J. Kopeček, R. Duncan, 1990, Biochemical pharmacology.

Synthetic polymers conjugated to monoclonal antibodies: vehicles for tumour-targeted drug delivery.

K. Ulbrich, V. Šubr, J. Cassidy, 1991, Selective cancer therapeutics.

Macromolecular prodrugs for use in targeted cancer chemotherapy: melphalan covalently coupled to N- (2-hydroxypropyl) methacrylamide copolymers

K. Ulbrich, V. Šubr, R. Duncan, 1991 .

Preclinical evaluation of polymer-bound doxorubicin

K. Ulbrich, V. Šubr, S. Wedge, 1992 .

Retargeting polymer‐coated adenovirus to the FGF receptor allows productive infection and mediates efficacy in a peritoneal model of human ovarian cancer

K. Ulbrich, V. Šubr, L. Seymour, 2008, The journal of gene medicine.

Coating of adeno‐associated virus with reactive polymers can ablate virus tropism, enable retargeting and provide resistance to neutralising antisera

K. Ulbrich, V. Šubr, R. Benjamin, 2008, The journal of gene medicine.

Cytotoxic and cytostatic effects of anti-Thy 1.2 targeted doxorubicin and cyclosporin A

K. Ulbrich, V. Šubr, B. Říhová, 1996 .

HPMA copolymers: 30 years of advances.

K. Ulbrich, T. Lammers, 2010, Advanced drug delivery reviews.

Comparison of the pharmacological and biological properties of HPMA copolymer‐pirarubicin conjugates: A single‐chain copolymer conjugate and its biodegradable tandem‐diblock copolymer conjugate

K. Ulbrich, H. Maeda, T. Etrych, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Nanotherapeutics shielded with a pH responsive polymeric layer.

K. Ulbrich, V. Šubr, T. Etrych, 2015, Physiological research.

Preclinical Evaluation of Linear HPMA-Doxorubicin Conjugates with pH-Sensitive Drug Release: Efficacy, Safety, and Immunomodulating Activity in Murine Model

K. Ulbrich, L. Kovář, T. Etrych, 2009, Pharmaceutical Research.

Clinical adenoviral gene therapy for prostate cancer.

Lindsay J. Georgopoulos, K. Ulbrich, A. Danielsson, 2010, Human gene therapy.

Tumour tropism and anti-cancer efficacy of polymer-based doxorubicin prodrugs in the treatment of subcutaneous murine B16F10 melanoma.

K. Ulbrich, V. Šubr, P. Steyger, 1994, British Journal of Cancer.

Star structure of antibody-targeted HPMA copolymer-bound doxorubicin: a novel type of polymeric conjugate for targeted drug delivery with potent antitumor effect.

K. Ulbrich, T. Etrych, B. Říhová, 2002, Bioconjugate chemistry.

Cytostatic and immunomobilizing activities of polymer-bound drugs: experimental and first clinical data.

K. Ulbrich, V. Šubr, T. Etrych, 2003, Journal of controlled release : official journal of the Controlled Release Society.

HPMA-hydrogels containing cytostatic drugs. Kinetics of the drug release and in vivo efficacy.

K. Ulbrich, T. Etrych, B. Říhová, 2002, Journal of controlled release : official journal of the Controlled Release Society.

Dual fluorescent HPMA copolymers for passive tumor targeting with pH-sensitive drug release II: impact of release rate on biodistribution.

K. Ulbrich, T. Etrych, T. Mueller, 2013, Journal of controlled release : official journal of the Controlled Release Society.

Dual fluorescent HPMA copolymers for passive tumor targeting with pH-sensitive drug release: synthesis and characterization of distribution and tumor accumulation in mice by noninvasive multispectral optical imaging.

K. Ulbrich, T. Etrych, T. Mueller, 2012, Biomacromolecules.

Preparation and properties of poly-(N-butylmethacrylamide) networks

K. Ulbrich, K. Dušek, J. Kopeček, 1978 .

Synthesis and properties of new N-(2-hydroxypropyl)methacrylamide copolymers containing thiazolidine-2-thione reactive groups

K. Ulbrich, V. Šubr, 2006 .

Polymer coatings for delivery of nucleic acid therapeutics.

K. Ulbrich, M. Tangney, L. Seymour, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Novel vectors for gene delivery formed by self-assembly of DNA with poly(L-lysine) grafted with hydrophilic polymers.

K. Ulbrich, E. Schacht, M. Wolfert, 1998, Biochimica et biophysica acta.

Coiled coil peptides as universal linkers for the attachment of recombinant proteins to polymer therapeutics.

K. Ulbrich, V. Král, O. Vaněk, 2011, Biomacromolecules.

Synergistic action of doxorubicin bound to the polymeric carrier based on N-(2-hydroxypropyl)methacrylamide copolymers through an amide or hydrazone bond.

K. Ulbrich, L. Kovář, T. Etrych, 2010, Molecular pharmaceutics.

Multi-component Polymeric System for Tumour Cell-Specific Gene Delivery Using a Universal Bungarotoxin Linker

K. Ulbrich, L. Seymour, R. Carlisle, 2010, Pharmaceutical Research.

Immunogenicity of N-(2-hydroxypropyl)-methacrylamide copolymers—Potential hapten or drug carriers

K. Ulbrich, B. Říhová, J. Kopeček, 2008, Folia Microbiologica.

Investigation of Nanoparticle Coating by Fluorescence Correlation Spectroscopy

K. Ulbrich, V. Šubr, P. Štěpánek, 2008 .

HPMA based macromolecular therapeutics: Internalization, intracellular pathway and cell death depend on the character of covalent bond between the drug and the peptidic spacer and also on spacer composition

K. Ulbrich, V. Šubr, T. Etrych, 2006, Journal of drug targeting.

Polymeric Conjugates of 9-[2-(Phosphonomethoxy)ethyl]purine with Potential Antiviral and Cytostatic Activity

K. Ulbrich, V. Šubr, M. Pechar, 2006 .

Hydroxybisphosphonate‐containing polymeric drug‐delivery systems designed for targeting into bone tissue

K. Ulbrich, T. Etrych, J. Kučka, 2006 .

Reduced cardiotoxicity of doxorubicin given in the form ofN-(2-hydroxypropyl) methacrylamide conjugates: an experimental study in the rat

T. K. Yeung, K. Ulbrich, J. Hopewell, 2004, Cancer Chemotherapy and Pharmacology.

Comparison of the binding kinetics of antibody-targeted N-(2-hydroxypropyl) methacrylamide (HPMA)-bound doxorubicin in vitro and in vivo

K. Ulbrich, B. Říhová, J. Strohalm, 1996 .

Synthetic Polymer Matrices for Neural Cell Transplantation

K. Ulbrich, S. Woerly, B. Říhová, 1993, Cell transplantation.

Soluble Synthetic Polymers for Targeting and Controlled Release of Anticancer Agents, Particularly Anthracycline Antibiotics

K. Ulbrich, J. Kopeček, R. Duncan, 1988 .

Pronounced Cellular Uptake of Pirarubicin versus That of Other Anthracyclines: Comparison of HPMA Copolymer Conjugates of Pirarubicin and Doxorubicin.

K. Ulbrich, H. Maeda, T. Etrych, 2016, Molecular pharmaceutics.

HPMA Copolymer-Conjugated Pirarubicin in Multimodal Treatment of a Patient with Stage IV Prostate Cancer and Extensive Lung and Bone Metastases

K. Ulbrich, H. Maeda, T. Etrych, 2016, Targeted Oncology.

Augmentation of EPR Effect and Efficacy of Anticancer Nanomedicine by Carbon Monoxide Generating Agents

K. Ulbrich, V. Šubr, H. Maeda, 2019, Pharmaceutics.

Two step mechanisms of tumor selective delivery of N-(2-hydroxypropyl)methacrylamide copolymer conjugated with pirarubicin via an acid-cleavable linkage.

K. Ulbrich, H. Maeda, T. Etrych, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Overcoming immunoescape mechanisms of BCL1 leukemia and induction of CD8+ T-cell-mediated BCL1-specific resistance in mice cured by targeted polymer-bound doxorubicin.

K. Ulbrich, L. Kovář, T. Etrych, 2008, Cancer research.

Doxorubicin Resistance in Mice Cured by Targeted Polymer-Bound Mediated BCL 1-Specific − T-Cell + and Induction of CD 8 Overcoming Immunoescape Mechanisms of BCL 1 Leukemia

K. Ulbrich, L. Kovář, T. Etrych, 2008 .

Intratumoural distribution as a determinant of tumour responsiveness to therapy using polymer-based macromolecular prodrugs

K. Ulbrich, P. Steyger, L. Seymour, 1996 .

Physical properties and in vitro transfection efficiency of gene delivery vectors based on complexes of DNA with synthetic polycations.

K. Ulbrich, L. Seymour, D. Oupický, 2002, Journal of controlled release : official journal of the Controlled Release Society.

Nanomedicines for inflammatory arthritis: head-to-head comparison of glucocorticoid-containing polymers, micelles, and liposomes.

K. Ulbrich, F. Kiessling, W. Hennink, 2014, ACS nano.

Molecular weight and polydispersity of calf-thymus DNA: static light-scattering and size-exclusion chromatography with dual detection.

K. Ulbrich, J. Horský, R. Laga, 2009, Biomacromolecules.

Targeting adenovirus gene delivery to activated tumour-associated vasculature via endothelial selectins

K. Ulbrich, V. Šubr, L. Seymour, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Click chemistry as a powerful and chemoselective tool for the attachment of targeting ligands to polymer drug carriers

K. Ulbrich, M. Pechar, R. Pola, 2014 .

Synthetic polymer derivatives as substrata for neuronal adhesion and growth

K. Ulbrich, V. Šubr, S. Woerly, 1993, Brain Research Bulletin.

Synergistic effect of EMF–BEMER-type pulsed weak electromagnetic field and HPMA-bound doxorubicin on mouse EL4 T-cell lymphoma

K. Ulbrich, T. Etrych, B. Říhová, 2011, Journal of drug targeting.

Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymer-based drug delivery systems.

K. Ulbrich, V. Šubr, W. Hennink, 2006, Neoplasia.

HPMA-copolymer conjugates targeted to tumor endothelium using synthetic oligopeptides

K. Ulbrich, B. Říhová, D. Větvička, 2009, Journal of drug targeting.

Overcoming multidrug resistance in Dox-resistant neuroblastoma cell lines via treatment with HPMA copolymer conjugates containing anthracyclines and P-gp inhibitors.

K. Ulbrich, V. Šubr, T. Etrych, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Spectral analysis of doxorubicin accumulation and the indirect quantification of its DNA intercalation.

K. Ulbrich, V. Šubr, Martin Strohalm, 2010, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Adenovirus-derived vectors for prostate cancer gene therapy.

Lindsay J. Georgopoulos, K. Ulbrich, S. Kochanek, 2010, Human gene therapy.

Abnormal differentiation of thymocytes induced by free cyclosporine is avoided when cyclosporine bound to N-(2-hydroxypropyl)methacrylamide copolymer carrier is used.

K. Ulbrich, B. Říhová, P. Rossmann, 1997, Transplantation.

Novel Polymeric Nanoparticles Assembled by Metal Ion Addition

K. Ulbrich, P. Štěpánek, G. Karlsson, 2011 .

Effect of pre-immunisation on the activity of polymer-doxorubicin against murine L1210 leukaemia

K. Ulbrich, R. Duncan, J. Strohalm, 1993 .

Core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin.

K. Ulbrich, C. van Nostrum, W. Hennink, 2010, Biomaterials.

Tropism ablation and stealthing of oncolytic adenovirus enhances systemic delivery to tumors and improves virotherapy of cancer.

K. Ulbrich, V. Šubr, N. Van Rooijen, 2012, Nanomedicine.

Evaluation of protein-N-(2-hydroxypropyl) methacrylamide copolymer conjugates as targetable drug-carriers. 2. Body distribution of conjugates containing transferrin, antitransferrin receptor antibody or anti-Thy 1.2 antibody and effectiveness of transferrin-containing daunomycin conjugates against m

K. Ulbrich, V. Šubr, R. Duncan, 1992 .

HPMA-based polymer conjugates with drug combination.

K. Ulbrich, T. Etrych, H. Krakovicová, 2009, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Intracerebral Implantation of Hydrogel-Coupled Adhesion Peptides: Tissue Reaction

K. Ulbrich, V. Šubr, S. Woerly, 1995, Journal of neural transplantation & plasticity.

Influence of hydrophilicity of cationic polymers on the biophysical properties of polyelectrolyte complexes formed by self-assembly with DNA.

K. Ulbrich, P. Dash, Martin L Read, 2000, Biochimica et biophysica acta.

Cationic Graft Copolymers as Carriers for Delivery of Antisense-Oligonucleotides

K. Ulbrich, Arkadiy V. Zintchenko, H. Dautzenberg, 2003 .

Hydrolytically and Reductively Degradable High-Molecular-Weight Poly(ethylene glycol)s

K. Ulbrich, M. Pechar, R. Laga, 2007 .

Synthesis and Properties of Poly[N-(2-Hydroxypropyl) Methacrylamide] Conjugates of Superoxide Dismutase

K. Ulbrich, T. Kondo, T. Etrych, 2002 .

Conjugates of Semitelechelic Poly[N-(2-Hydroxypropyl)Methacrylamide] with Enzymes for Protein Delivery

K. Ulbrich, B. Říhová, D. Oupický, 1999 .

DNA complexes with block and graft copolymers of N-(2-hydroxypropyl)methacrylamide and 2-(trimethylammonio)ethyl methacrylate.

K. Ulbrich, D. Oupický, Č. Koňák, 1999, Journal of biomaterials science. Polymer edition.

DNA interactions of 2-pyrrolinodoxorubicin, a distinctively more potent daunosamine-modified analogue of doxorubicin.

K. Ulbrich, V. Brabec, J. Kašpárková, 2011, Biochemical pharmacology.

Synthesis and Properties of Star HPMA Copolymer Nanocarriers Synthesised by RAFT Polymerisation Designed for Selective Anticancer Drug Delivery and Imaging.

K. Ulbrich, T. Etrych, O. Janoušková, 2015, Macromolecular bioscience.

New HPMA copolymer-based drug carriers with covalently bound hydrophobic substituents for solid tumour targeting.

K. Ulbrich, T. Etrych, T. Mrkvan, 2008, Journal of controlled release : official journal of the Controlled Release Society.

Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers.

K. Ulbrich, V. Šubr, T. Etrych, 2005, Journal of controlled release : official journal of the Controlled Release Society.

Polycationic graft copolymers as carriers for oligonucleotide delivery. Complexes of oligonucleotides with polycationic graft copolymers.

K. Ulbrich, V. Šubr, Arkadiy V. Zintchenko, 2001 .

Biocompatibility of Biopolymers

K. Ulbrich, V. Vetvicka, B. Říhová, 1992 .

Synthesis and characterization of HE-24.8: a polymeric contrast agent for magnetic resonance angiography.

M. Bock, L. Schad, K. Ulbrich, 2006, Bioconjugate chemistry.

Hydrolytically degradable polymer micelles for drug delivery: a SAXS/SANS kinetic study.

K. Ulbrich, D. Svergun, P. Štěpánek, 2013, Biomacromolecules.

Thermoresponsive Polymer Micelles as Potential Nanosized Cancerostatics.

K. Ulbrich, T. Etrych, S. Filippov, 2015, Biomacromolecules.

Polymer conjugates of doxorubicin bound through an amide and hydrazone bond: Impact of the carrier structure onto synergistic action in the treatment of solid tumours.

K. Ulbrich, V. Šubr, T. Etrych, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Polymer carriers for anticancer drugs targeted to EGF receptor.

K. Ulbrich, L. Kovář, T. Etrych, 2012, Macromolecular bioscience.

Hydrolytically Degradable Polymer Micelles for Anticancer Drug Delivery to Solid Tumors

K. Ulbrich, T. Etrych, P. Chytil, 2012 .

Polymer conjugates of the highly potent cytostatic drug 2-pyrrolinodoxorubicin.

K. Ulbrich, B. Říhová, M. Studenovský, 2011, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Use of synthetic vectors for neutralising antibody resistant delivery of replicating adenovirus DNA

K. Ulbrich, T. Etrych, S. Briggs, 2006, Gene Therapy.

Induction of Systemic Antitumour Resistance with Targeted Polymers

K. Ulbrich, V. Šubr, T. Mrkvan, 2005, Scandinavian journal of immunology.

In Vitro and In Vivo Effect of HPMA Copolymer-bound Doxorubicin Targeted to Transferrin Receptor of B-cell Lymphoma 38C13

K. Ulbrich, B. Říhová, J. Strohalm, 2002, Journal of drug targeting.

A possibility to overcome P-glycoprotein (PGP)-mediated multidrug resistance by antibody-targeted drugs conjugated to N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer carrier.

K. Ulbrich, B. Říhová, J. Strohalm, 1999, European journal of cancer.

Structural changes on polymeric nanoparticles induced by hydrophobic drug entrapment

K. Ulbrich, P. Štěpánek, J. Putaux, 2018 .

Decreased Binding to Proteins and Cells of Polymeric Gene Delivery Vectors Surface Modified with a Multivalent Hydrophilic Polymer and Retargeting through Attachment of Transferrin*

K. Ulbrich, V. Šubr, M. Wolfert, 2000, The Journal of Biological Chemistry.

Fine tuning of the pH-dependent drug release rate from polyHPMA-ellipticinium conjugates.

K. Ulbrich, D. Větvička, O. Sedláček, 2013, Bioorganic & medicinal chemistry.

Antitumor activity of IL‐2/anti‐IL‐2 mAb immunocomplexes exerts synergism with that of N‐(2‐hydroxypropyl)methacrylamide copolymer‐bound doxorubicin conjugate due to its low immunosuppressive activity

K. Ulbrich, B. Říhová, M. Šírová, 2011, International journal of cancer.

Poly(allyl glycidyl ether)-block-poly(ethylene oxide): A novel promising polymeric intermediate for the preparation of micellar drug delivery systems

K. Ulbrich, M. Hrubý, Č. Koňák, 2005 .

Synthesis of HPMA Copolymers Containing Doxorubicin Bound via a Hydrazone Linkage. Effect of Spacer on Drug Release and in vitro Cytotoxicity

K. Ulbrich, T. Etrych, B. Říhová, 2002 .

Avidin-conjugated polymers with monobiotinylated antibody fragments: A new strategy for the noncovalent attachment of recombinant proteins for polymer therapeutics

K. Ulbrich, V. Král, M. Pechar, 2013 .

Novel biodegradable hydrogels prepared using the divinylic crosslinking agent N,O-dimethacryloylhydroxylamine. 1. Synthesis and characterisation of rates of gel degradation, and rate of release of model drugs, in vitro and in vivo

K. Ulbrich, V. Šubr, R. Duncan, 1993 .

Gamma scintigraphy of a 123I-labelled N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin conjugate containing galactosamine following intravenous administration to nude mice bearing hepatic human colon carcinoma.

K. Ulbrich, A. Perkins, R. Duncan, 1996, Journal of drug targeting.

Macromolecular HPMA-based nanoparticles with cholesterol for solid-tumor targeting: detailed study of the inner structure of a highly efficient drug delivery system.

K. Ulbrich, D. Svergun, P. Štěpánek, 2012, Biomacromolecules.

HPMA‐based Biodegradable Hydrogels Containing Different Forms of Doxorubicin Antitumor Effects and Biocompatibility a

K. Ulbrich, V. Šubr, B. Říhová, 1997, Annals of the New York Academy of Sciences.

Polymeric carriers of drugs for site‐specific therapy

K. Ulbrich, V. Šubr, B. Říhová, 1997 .

Gamma Scintigraphy of the Biodistribution of 123I-Labelled N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates in Mice with Transplanted Melanoma and Mammary Carcinoma

K. Ulbrich, A. Perkins, R. Duncan, 1996 .

Development of N-(2-hydroxypropyl)methacrylamide copolymer conjugates for delivery of cancer chemotherapy

K. Ulbrich, R. Duncan, 1993 .

Targeting of N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin conjugate to the hepatocyte galactose-receptor in mice: visualisation and quantification by gamma scintigraphy as a basis for clinical targeting studies.

K. Ulbrich, A. Perkins, R. Duncan, 1993, Journal of drug targeting.

Adsorption and activation of zymogens at solid-liquid interfaces. I. Chymotrypsinogen on alkylamino modified silica derivatives.

K. Ulbrich, J. Kopeček, S. Oscarsson, 1994, Journal of biomedical materials research.

Polymeric anticancer drugs with pH-controlled activation.

K. Ulbrich, T. Etrych, B. Říhová, 2004, International journal of pharmaceutics.

Polyelectrolyte vectors for gene delivery: influence of cationic polymer on biophysical properties of complexes formed with DNA.

K. Ulbrich, M. Wolfert, S. Smart, 1999, Bioconjugate chemistry.

Characterization of vectors for gene therapy formed by self-assembly of DNA with synthetic block co-polymers.

K. Ulbrich, E. Schacht, M. Wolfert, 1996, Human gene therapy.

Biodegradable drug carriers based on poly(ethylene glycol) block copolymers

K. Ulbrich, E. Schacht, J. Strohalm, 1997 .

SYNTHESIS OF POLY(ETHYLENE GLYCOL) BLOCK COPOLYMERS AS POTENTIAL WATER-SOLUBLE DRUG CARRIERS

K. Ulbrich, J. Strohalm, M. Pechar, 1995 .

Acquired and specific immunological mechanisms co-responsible for efficacy of polymer-bound drugs.

K. Ulbrich, B. Říhová, O. Hovorka, 2002, Journal of controlled release : official journal of the Controlled Release Society.

Detection and cellular localisation of the synthetic soluble macromolecular drug carrier pHPMA

K. Ulbrich, V. Šubr, J. Debus, 2002, European Journal of Nuclear Medicine and Molecular Imaging.

HPMA copolymer-bound doxorubicin targeted to tumor-specific antigen of BCL1 mouse B cell leukemia.

K. Ulbrich, T. Etrych, T. Mrkvan, 2003, Journal of controlled release : official journal of the Controlled Release Society.

Conjugates of doxorubicin with graft HPMA copolymers for passive tumor targeting.

K. Ulbrich, T. Etrych, T. Mrkvan, 2008, Journal of controlled release : official journal of the Controlled Release Society.

HPMA copolymers with pH-controlled release of doxorubicin: in vitro cytotoxicity and in vivo antitumor activity.

K. Ulbrich, T. Etrych, B. Říhová, 2003, Journal of controlled release : official journal of the Controlled Release Society.

Polymer conjugates of acridine-type anticancer drugs with pH-controlled activation.

K. Ulbrich, J. Kovář, D. Větvička, 2012, Bioorganic & medicinal chemistry.

Synthesis of Biodegradable Polymers for Controlled Drug Release a

K. Ulbrich, V. Šubr, B. Říhová, 1997, Annals of the New York Academy of Sciences.

Phase transition parameters of potential thermosensitive drug release systems based on polymers of N-alkylmethacrylamides.

K. Ulbrich, M. Netopilík, M. Bohdanecký, 1997, Journal of biomaterials science. Polymer edition.

Polyoxazoline thermoresponsive micelles as radionuclide delivery systems.

K. Ulbrich, D. Větvička, J. Pánek, 2010, Macromolecular bioscience.

Polymer—Doxorubicin Conjugate with a Synthetic Peptide Ligand Targeted on Prostate Tumor

K. Ulbrich, M. Pechar, R. Pola, 2007 .

Conjugate of Doxorubicin with a Thermosensitive Polymer Drug Carrier

K. Ulbrich, V. Chtryt, 2001 .

Preparation and properties of poly(N-ethylmethacrylamide) networks

K. Ulbrich, K. Dušek, J. Kopeček, 1977 .

Poly[N-(2-hydroxypropyl)methacrylamide] conjugates of methotrexate: Synthesis and in vitro drug release

K. Ulbrich, V. Šubr, J. Strohalm, 1997 .

Polymers containing enzymatically degradable bonds, 9. Chymotrypsm catalyzed hydrolysis of a p‐nitroanilide drug model, p bound via oligopeptides onto poly(vinylpyrrolidone‐co‐maleic anhydride)

K. Ulbrich, J. Pató, J. Kopeček, 1984 .

Thermally Controlled Association in Aqueous Solutions of Diblock Copolymers of Poly[N-(2-hydroxypropyl)methacrylamide] and Poly(N-isopropylacrylamide)

K. Ulbrich, D. Oupický, Č. Koňák, 2000 .

Cloud point of poly(N‐isopropylmethacrylamide) solutions in water: is it really a point?

K. Ulbrich, M. Netopilík, M. Bohdanecký, 1997 .

Self-assembly of biodegradable copolyester and reactive HPMA-based polymers into nanoparticles as an alternative stealth drug delivery system

K. Ulbrich, P. Štěpánek, J. Putaux, 2012 .

HPMA copolymer conjugates of paclitaxel and docetaxel with pH-controlled drug release.

K. Ulbrich, T. Etrych, B. Říhová, 2010, Molecular pharmaceutics.

Novel “soft” biodegradable nanoparticles prepared from aliphatic based monomers as a potential drug delivery system

K. Ulbrich, P. Štěpánek, B. Říhová, 2012 .

Intraperitoneal and subcutaneous retention of a soluble polymeric drug-carrier bearing galactose

K. Ulbrich, J. Kopeček, R. Duncan, 1991 .

Radical polymerization of n-substituted methacrylamides

K. Ulbrich, J. Kopeček, 1976 .

iBodies: Modular Synthetic Antibody Mimetics Based on Hydrophilic Polymers Decorated with Functional Moieties

K. Ulbrich, V. Šubr, J. Konvalinka, 2016, Angewandte Chemie.

Doxorubicin attached to HPMA copolymer via amide bond modifies the glycosylation pattern of EL4 cells

K. Ulbrich, V. Šubr, L. Kovář, 2010, Tumor Biology.

Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers.

K. Ulbrich, V. Šubr, W. Hennink, 2009, Biomaterials.

Passive versus active tumor targeting using RGD- and NGR-modified polymeric nanomedicines.

Fabian Kiessling, Gert Storm, Felix Gremse, 2014, Nano letters.

Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1

K. Ulbrich, V. Šubr, Robert B Sim, 2009, Blood.

Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies

K. Ulbrich, L. Seymour, V. Mautner, 2001, Gene Therapy.

Image-guided and passively tumour-targeted polymeric nanomedicines for radiochemotherapy

K. Ulbrich, V. Šubr, J. Debus, 2008, British Journal of Cancer.

Effect of radiotherapy and hyperthermia on the tumor accumulation of HPMA copolymer-based drug delivery systems.

K. Ulbrich, V. Šubr, J. Debus, 2007, Journal of controlled release : official journal of the Controlled Release Society.

Fluorescent boronate-based polymer nanoparticles with reactive oxygen species (ROS)-triggered cargo release for drug-delivery applications.

Petr Štěpánek, Jiří Pánek, Martin Hrubý, 2016, Nanoscale.

Synthesis of poly[N-(2-hydroxypropyl)methacrylamide] conjugates of inhibitors of the ABC transporter that overcome multidrug resistance in doxorubicin-resistant P388 cells in vitro.

K. Ulbrich, V. Šubr, B. Říhová, 2014, Biomacromolecules.

Impact of Polymer-TLR-7/8 Agonist (Adjuvant) Morphology on the Potency and Mechanism of CD8 T Cell Induction.

Michael Y. Gerner, K. Ulbrich, A. Wang, 2019, Biomacromolecules.

Augmentation of the Enhanced Permeability and Retention Effect with Nitric Oxide–Generating Agents Improves the Therapeutic Effects of Nanomedicines

K. Ulbrich, V. Šubr, H. Maeda, 2018, Molecular Cancer Therapeutics.

Effect of albumin and polyanion on the structure of DNA complexes with polycation containing hydrophilic nonionic block.

K. Ulbrich, P. Dash, L. Seymour, 1999, Bioconjugate chemistry.

Virotherapy of ovarian cancer with polymer-cloaked adenovirus retargeted to the epidermal growth factor receptor.

K. Ulbrich, V. Šubr, S. Kehoe, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

Chick embryo lethal orphan virus can be polymer-coated and retargeted to infect mammalian cells

K. Ulbrich, E. Boos, N. Rooijen, 2006, Gene Therapy.

Poly(ethylene oxide)-coated polyamide nanoparticles degradable by glutathione

Martin Hrubý, K. Ulbrich, M. Hrubý, 2007 .

Synthesis of Macromolecular Conjugates of a Urokinase Inhibitor: Amiloride

K. Ulbrich, V. Šubr, J. Pató, 1999 .

Polymers containing enzymatically degradable bonds, XII. Effect of spacer structure on the rate of release of daunomycin and adriamycin from poly [N-(2-hydroxypropyl)-methacrylamide] copolymer drag carriers in vitro and antitumour activity measured in vivo

K. Ulbrich, V. Šubr, R. Duncan, 1992 .

HPMA Copolymer-Drug Conjugates with Controlled Tumor-Specific Drug Release.

K. Ulbrich, T. Etrych, E. Koziolová, 2018, Macromolecular bioscience.

HPMA copolymer conjugates with reduced anti-CD20 antibody for cell-specific drug targeting. I. Synthesis and in vitro evaluation of binding efficacy and cytostatic activity.

K. Ulbrich, L. Kovář, T. Etrych, 2009, Journal of controlled release : official journal of the Controlled Release Society.

Star-shaped immunoglobulin-containing HPMA-based conjugates with doxorubicin for cancer therapy.

K. Ulbrich, T. Etrych, T. Mrkvan, 2007, Journal of controlled release : official journal of the Controlled Release Society.

Properties of HPMA copolymer-doxorubicin conjugates with pH-controlled activation: effect of polymer chain modification.

K. Ulbrich, T. Etrych, T. Mrkvan, 2006, Journal of controlled release : official journal of the Controlled Release Society.

Antibody-targeted Polymer–doxorubicin Conjugates with pH-controlled Activation

K. Ulbrich, T. Etrych, B. Říhová, 2004, Journal of drug targeting.

Synthesis of novel hydrolytically degradable hydrogels for controlled drug release

K. Ulbrich, 1995 .

N-(2-hydroxypropyl)methacrylamide copolymers targeted to the hepatocyte galactose-receptor: pharmacokinetics in DBA2 mice.

K. Ulbrich, S. Wedge, R. Duncan, 1991, British Journal of Cancer.

pH-triggered block copolymer micelles based on a pH-responsive PDPA (poly[2-(diisopropylamino)ethyl methacrylate]) inner core and a PEO (poly(ethylene oxide)) outer shell as a potential tool for the cancer therapy

Petr Stepanek, Eliézer Jäger, Alessandro Jäger, 2011 .

Poly[N-(2-hydroxypropyl)methacrylamide]-based tissue-embedding medium compatible with MALDI mass spectrometry imaging experiments.

K. Ulbrich, Martin Strohalm, V. Havlíček, 2011, Analytical chemistry.

Enhanced Tumor Uptake and Penetration of Virotherapy Using Polymer Stealthing and Focused Ultrasound

James J. Choi, K. Ulbrich, V. Šubr, 2013, Journal of the National Cancer Institute.

Polymer-conjugated bovine pancreatic and seminal ribonucleases inhibit growth of human tumors in nude mice.

K. Ulbrich, M. Zadinová, P. Poučková, 2004, Journal of controlled release : official journal of the Controlled Release Society.

Poly [N -(2-hydroxypropyl)methacrylamide] Conjugates of Bovine Pancreatic Ribonuclease (RNase A) Inhibit Growth of Human Melanoma in Nude Mice

K. Ulbrich, M. Zadinová, P. Poučková, 2002, Journal of drug targeting.

Polymer conjugated bovine seminal ribonuclease inhibits growth of solid tumors and development of metastases in mice.

K. Ulbrich, M. Zadinová, P. Poučková, 2001, Neoplasma.

Biological evaluation of polymeric micelles with covalently bound doxorubicin.

K. Ulbrich, L. Kovář, T. Etrych, 2009, Bioconjugate chemistry.

N-(2-Hydroxypropyl)methacrylamide-based polymer conjugates with pH-controlled activation of doxorubicin for cell-specific or passive tumour targeting. Synthesis by RAFT polymerisation and physicochemical characterisation.

K. Ulbrich, V. Šubr, T. Etrych, 2010, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Interaction of HPMA copolymer-doxorubicin conjugates with human liver microsomal cytochromes P450. Comparison with free doxorubicin. Names of authors:

K. Ulbrich, P. Anzenbacher, 2011 .

New bioerodable thermoresponsive polymers for possible radiotherapeutic applications.

K. Ulbrich, J. Kozempel, M. Babič, 2007, Journal of controlled release : official journal of the Controlled Release Society.

Differences in the intracellular fate of free and polymer-bound doxorubicin.

K. Ulbrich, V. Šubr, T. Etrych, 2002, Journal of controlled release : official journal of the Controlled Release Society.

Multi-responsive polymer micelles as ellipticine delivery carriers for cancer therapy.

K. Ulbrich, J. Pánek, O. Sedláček, 2015, Anticancer research.

N‐(2‐hydroxypropyl)methacrylamide polymer conjugated pyropheophorbide‐a, a promising tumor‐targeted theranostic probe for photodynamic therapy and imaging

K. Ulbrich, V. Šubr, S. Hackbarth, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

HPMA copolymer conjugate with pirarubicin: In vitro and ex vivo stability and drug release study.

K. Ulbrich, H. Maeda, T. Etrych, 2018, International journal of pharmaceutics.

Coiled coil peptides and polymer-peptide conjugates: synthesis, self-assembly, characterization and potential in drug delivery systems.

K. Ulbrich, O. Vaněk, S. Filippov, 2014, Biomacromolecules.

Thermoresponsive micelles for radionuclide delivery.

K. Ulbrich, J. Pánek, S. Filippov, 2010, Journal of Controlled Release.

Polymeric nanomedicines for image-guided drug delivery and tumor-targeted combination therapy

Fabian Kiessling, Gert Storm, Twan Lammers, 2010 .

Overcoming multidrug resistance using folate receptor-targeted and pH-responsive polymeric nanogels containing covalently entrapped doxorubicin.

K. Ulbrich, W. Hennink, T. Etrych, 2017, Nanoscale.

Polymers containing enzymatically degradable bonds. VI. Hydrophilic gels cleavable by chymotrypsin.

K. Ulbrich, J. Kopeček, J Kopecek, 1982, Biomaterials.

Cross‐linked copolymers of N,N‐diethylacrylamide with improved mechanical properties

K. Ulbrich, J. Kopeček, 2007 .

Chemotherapy based on HPMA copolymer conjugates with pH-controlled release of doxorubicin triggers anti-tumor immunity.

K. Ulbrich, T. Etrych, T. Mrkvan, 2005, Journal of controlled release : official journal of the Controlled Release Society.

Influence of molecular weight on passive tumour accumulation of a soluble macromolecular drug carrier.

K. Ulbrich, H. Maeda, R. Duncan, 1995, European journal of cancer.

HPMA-hydrogels result in prolonged delivery of anticancer drugs and are a promising tool for the treatment of sensitive and multidrug resistant leukaemia.

K. Ulbrich, T. Etrych, B. Říhová, 2002, European journal of cancer.

Poly(ethylene glycol) multiblock copolymer as a carrier of anti-cancer drug doxorubicin.

K. Ulbrich, V. Šubr, E. Schacht, 2000, Bioconjugate chemistry.

Physicochemical and biological characterisation of an antisense oligonucleotide targeted against the bcl-2 mRNA complexed with cationic-hydrophilic copolymers.

K. Ulbrich, E. Schacht, A. Clark, 2000, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Removable nanocoatings for siRNA polyplexes.

K. Ulbrich, V. Šubr, M. Neeman, 2011, Bioconjugate chemistry.

Preparation of DNA complexes with diblock copolymers of poly[N(2-hydroxypropyl)methacrylamide] and polycations

K. Ulbrich, D. Oupický, Č. Koňák, 1999 .

Noninvasive optical imaging of nanomedicine biodistribution.

Fabian Kiessling, Gert Storm, Felix Gremse, 2013, ACS nano.

The structure-dependent toxicity, pharmacokinetics and anti-tumour activity of HPMA copolymer conjugates in the treatment of solid tumours and leukaemia.

K. Ulbrich, T. Etrych, B. Říhová, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Formation of DNA complexes with diblock copolymers of poly(N-(2-hydroxypropyl) methacrylamide) and polycations

K. Ulbrich, L. Seymour, Č. Koňák, 1998 .

Photodynamic therapy and imaging based on tumor-targeted nanoprobe, polymer-conjugated zinc protoporphyrin

K. Ulbrich, V. Šubr, H. Maeda, 2015, Future science OA.

Increasing the density of nanomedicines improves their ultrasound-mediated delivery to tumours.

K. Ulbrich, L. Seymour, R. Carlisle, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Traceless Bioresponsive Shielding of Adenovirus Hexon with HPMA Copolymers Maintains Transduction Capacity In Vitro and In Vivo

K. Ulbrich, V. Šubr, S. Kochanek, 2014, PloS one.

HPMA-based polymer therapeutics improve the efficacy of surgery, of radiotherapy and of chemotherapy combinations.

K. Ulbrich, V. Šubr, F. Kiessling, 2010, Nanomedicine.

Overcoming cellular multidrug resistance using classical nanomedicine formulations.

K. Ulbrich, F. Kiessling, T. Etrych, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Multifunctional cytotoxic stealth nanoparticles. A model approach with potential for cancer therapy.

K. Ulbrich, V. Šubr, G. Decher, 2009, Nano letters.

HPMA copolymer-bound doxorubicin induces immunogenic tumor cell death.

K. Ulbrich, L. Kovář, T. Etrych, 2013, Current medicinal chemistry.

Immunoprotective therapy with targeted anticancer drugs

K. Ulbrich, E. Schacht, B. Říhová, 2001 .

Cytotoxic and Immunomodulatory Activites of Polymer-Bound Drugs

K. Ulbrich, V. Šubr, T. Etrych, 2004 .

Antiproliferative effect of a lectin- and anti-Thy-1.2 antibody-targeted HPMA copolymer-bound doxorubicin on primary and metastatic human colorectal carcinoma and on human colorectal carcinoma transfected with the mouse Thy-1.2 gene.

K. Ulbrich, B. Říhová, O. Hovorka, 2000, Bioconjugate chemistry.

Permeability of hydrophilic membranes based on N-substituted (meth)acrylamides

K. Ulbrich, J. Kopeček, J. Vacík, 1978 .

Synergistic effect of HPMA copolymer-bound doxorubicin and dexamethasone in vivo on mouse lymphomas

K. Ulbrich, T. Etrych, B. Říhová, 2011 .

Polymer therapeutics with a coiled coil motif targeted against murine bcl1 leukemia.

K. Ulbrich, V. Král, M. Pechar, 2013, Biomacromolecules.

Chemical Conjugation of Cowpea Mosaic Viruses with Reactive HPMA-Based Polymers

K. Ulbrich, V. Šubr, R. Laga, 2010, Journal of biomaterials science. Polymer edition.

The comparison of in vivo properties of water-soluble HPMA-based polymer conjugates with doxorubicin prepared by controlled RAFT or free radical polymerization.

K. Ulbrich, T. Etrych, B. Říhová, 2015, Physiological research.

Synthetic macromolecular drug carriers: biodistribution of poly[(N-2-hydroxypropyl)methacrylamide] copolymers and their accumulation in solid rat tumors.

K. Ulbrich, V. Šubr, J. Debus, 2001, PDA journal of pharmaceutical science and technology.

Long‐Circulating and Passively Tumor‐Targeted Polymer‐Drug Conjugates Improve the Efficacy and Reduce the Toxicity of Radiochemotherapy

K. Ulbrich, V. Šubr, F. Kiessling, 2010 .

New, Hydrophilic, HPMA‐Based Polymers for Bioresponsive Shielding of Gene‐Delivery Vectors

K. Ulbrich, V. Šubr, R. Laga, 2009 .

Coating of vesicles with hydrophilic reactive polymers.

K. Ulbrich, V. Šubr, P. Štěpánek, 2008, Langmuir : the ACS journal of surfaces and colloids.

Coating of nanoparticles bearing amino groups on the surface with hydrophilic HPMA-based polymers

K. Ulbrich, V. Šubr, R. Laga, 2007 .

Steric stabilization of poly-L-Lysine/DNA complexes by the covalent attachment of semitelechelic poly[N-(2-hydroxypropyl)methacrylamide].

K. Ulbrich, P. Dash, L. Seymour, 2000, Bioconjugate chemistry.

Coating of DNA/poly(L-lysine) complexes by covalent attachment of poly[N-(2-hydroxypropyl)methacrylamide].

K. Ulbrich, V. Šubr, R. Laga, 2006, Biomacromolecules.

Biodegradable star HPMA polymer conjugates of doxorubicin for passive tumor targeting.

K. Ulbrich, T. Etrych, J. Strohalm, 2011, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Starlike vs. Classic Macromolecular Prodrugs: Two Different Antibody-Targeted HPMA Copolymers of Doxorubicin Studied in Vitro and in Vivo as Potential Anticancer Drugs

Markéta Jelínková, K. Ulbrich, T. Etrych, 2003, Pharmaceutical Research.

Doxorubicin bound to a HPMA copolymer carrier through hydrazone bond is effective also in a cancer cell line with a limited content of lysosomes.

K. Ulbrich, T. Etrych, B. Říhová, 2001, Journal of controlled release : official journal of the Controlled Release Society.

A Novel Approach to Increase the Stability of Liposomal Containers via In Prep Coating by Poly[N -(2-Hydroxypropyl)Methacrylamide] with Covalently Attached Cholesterol Groups

K. Ulbrich, T. Etrych, L. Kováčik, 2018 .

POLY(HPMA)-COATED LIPOSOMES DEMONSTRATE PROLONGED CIRCULATION IN MICE

K. Ulbrich, V. Šubr, V. Torchilin, 2001, Journal of liposome research.

HPMA copolymer conjugates of DOX and mitomycin C for combination therapy: physicochemical characterization, cytotoxic effects, combination index analysis, and anti-tumor efficacy.

K. Ulbrich, T. Etrych, B. Říhová, 2013, Macromolecular bioscience.

Polymeric conjugates of drugs and antibodies for site‐specific drug delivery

K. Ulbrich, V. Šubr, B. Říhová, 1996 .