H. Schoemaker

H. Schoemaker, J. M. Palmer, P. Harvey, 1987, Philosophical Transactions of the Royal Society of London. Series A, Mathematical and Physical Sciences.

Synthetic applications of aliphatic unsaturated alpha-H-alpha-amino acids.

H. Schoemaker, F. Rutjes, F. V. van Delft, 2005, Organic & biomolecular chemistry.

Ring-closing alkyne metathesis mediated synthesis of cyclic beta-turn mimetics

H. Schoemaker, J. H. Boom, F. Rutjes, 2004 .

Palladium-Catalyzed Cyclization Reactions of Acetylene-Containing Amino Acids

H. Schoemaker, F. Rutjes, H. Hiemstra, 2002 .

Synthesis of diaminosuberic acid derivatives via ring-closing alkyne metathesis.

H. Schoemaker, G. A. van der Marel, J. V. van Hest, 2001, Journal of Organic Chemistry.

Enzymatic resolution of Cα-fluoroalkyl substituted amino acids

H. Schoemaker, Q. Broxterman, B. Koksch, 2004 .

Enzymatic and chiral HPLC resolution of α-azido acids and amides

H. Schoemaker, M. Meldal, C. W. Tornøe, 2000 .

Synthesis of Enantiopure Functionalized Pipecolic Acids via Amino Acid Derived N‐Acyliminium Ions

Wim J. N. Meester, H. Schoemaker, F. Rutjes, 1999 .

Ruthenium-catalyzed ring closing olefin metathesis of non-natural α-amino acids

H. Schoemaker, F. Rutjes, 1997 .

Synthesis of dipeptides containing a-substituted amino acids; their use as chiral ligands in Lewis-acid-catalyzed reactions

H. Schoemaker, B. Kaptein, Q. Broxterman, 2010 .

Enzymatic Resolution of α,α-Disubstituted α-Amino Acid Esters and Amides.

H. Schoemaker, B. Kaptein, Q. Broxterman, 1993 .

Synthesis of α,α-disubstituted α-amino acid amides by phase-transfer catalyzed alkylation

H. Schoemaker, B. Kaptein, Q. Broxterman, 1992 .

PIG-LIVER ESTERASE CATALYZED HYDROLYZES OF RACEMIC ALPHA-SUBSTITUTED ALPHA-HYDROXY ESTERS

H. Schoemaker, B. Kaptein, H. Moorlag, 1990 .

New Mechanism of the C α —Cß Cleavage in Non-Phenolic Arylglycerol ß-Aryl Ether Lignin Substructures Catalyzed by Lignin Peroxidase

H. Schoemaker, T. Lundell, A. Hatakka, 1993 .

SL 84.0418: a new alpha-2 antagonist with anti-hyperglycaemic properties

H. Schoemaker, A. Oblin, S. Z. Langer, 1990 .

The 2-oxo-thiazolidinium moiety as a novel initiating center for stereoselective olefin cyclisations

H. Schoemaker, W. Speckamp, J. Hamersma, 1979 .

Do carbohydrates play a role in the lignin peroxidase cycle? Redox catalysis in the endergonic region of the driving force.

H. Schoemaker, T. Glumoff, K. Piontek, 1994, Bioorganic & medicinal chemistry.

SL651498: An Anxioselective Compound with Functional Selectivity for a 2 - and a 3 -Containing g -Aminobutyric Acid A (GABA A ) Receptors

G. Perrault, H. Schoemaker, G. Griebel, 2001 .

Cu‐Catalyzed Formation of Triazole‐Linked Glycoamino Acids and Application in Chemoenzymatic Peptide Synthesis.

H. Schoemaker, F. Rutjes, F. L. Delft, 2008 .

The sulphoxidation of thioanisole catalysed by lactoperoxidase and Coprinus cinereus peroxidase: evidence for an oxygen-rebound mechanism.

H. Schoemaker, H. Dekker, R. Wever, 1998, European journal of biochemistry.

Lignin peroxidase L3 from Phlebia radiata. Pre-steady-state and steady-state studies with veratryl alcohol and a non-phenolic lignin model compound 1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol.

H. Schoemaker, T. Lundell, A. Hatakka, 1993, European journal of biochemistry.

Pre-steady-state kinetic study on the formation of compound I and II of ligninase.

H. Schoemaker, P. Harvey, J. Palmer, 1989, Biochimica et biophysica acta.

Lignin degradeation by white rot fungi

H. Schoemaker, P. Harvey, J. Palmer, 1987 .

Optimization of the kinetic resolution of the DL-phosphomonoesters of threonine and serine by random mutagenesis of the acid phosphatase from Salmonella enterica

H. Schoemaker, H. Ruijssenaars, A. Hartog, 2007 .

Simple enzymatic in situ generation of dihydroxyacetone phosphate and its use in a cascade reaction for the production of carbohydrates: increased efficiency by phosphate cycling.

H. Schoemaker, A. Hartog, R. Wever, 2006, The Journal of organic chemistry.

Applications of Aliphatic Unsaturated Non-proteinogenic α-H-α-Amino Acid

H. Schoemaker, F. Rutjes, L. B. Wolf, 2001 .

Enzymatic Catalysis in Organic Synthesis. Synthesis of Enantiomerically Pure Calpha-Substituted alpha-Amino and alpha-Hydroxy Acids.

H. Schoemaker, B. Kaptein, Q. Broxterman, 1996 .

Synthesis of (optically active) sulfur-containing trifunctional amino acids by radical addition to (optically active) unsaturated amino acids

H. Schoemaker, B. Kaptein, Q. Broxterman, 1992 .

Pd-Catalyzed Cyclization Reactions of Acetylene-Containing α-Amino Acids.

H. Schoemaker, F. Rutjes, H. Hiemstra, 1998 .

Application of Enzymes in Industrial Organic Synthesis

H. Schoemaker, B. Kaptein, Q. Broxterman, 1997, CHIMIA.

Metabolism of a lignin model compound, 3,4-dimethoxy benzyl alcohol by Phanerochaete chrysosporium

H. Schoemaker, M. Leisola, A. Fiechter, 1988 .

Isolation and characterization of substituted 4-hydroxy-cyclohex-2-enones as metabolites of 3,4-dimethoxybenzyl alcohol and its methyl ether in ligninolytic cultures of Phanerochaete chrysosporium

H. Schoemaker, M. Leisola, U. Tuor, 1993, Applied Microbiology and Biotechnology.

CHAPTER 37 – ON THE METABOLISM OF 3,4 - DIMETHOXYBENZYL ALCOHOL AND ITS METHYL ETHER BY PHANEROCHAETE CHRYSOSPORIUM

H. Schoemaker, M. Leisola, U. Tuor, 1990 .

Mechanisms of ligninase catalysis

H. Schoemaker, P. Harvey, J. Palmer, 1987 .

[3H]-5-Methoxytryptoline is not actively accumulated by rabbit platelets

H. Schoemaker, S. Z. Langer, A. Segonzac, 1987, Naunyn-Schmiedeberg's Archives of Pharmacology.

Temperature Dependence of Drug Interaction with the Platelet 5‐Hydroxytryptamine Transporter: A Clue to the Imipramine Selectivity Paradox

H. Schoemaker, S. Z. Langer, A. Segonzac, 1987, Journal of neurochemistry.

[3H]Imipramine binding and [3H]5HT uptake in human blood platelets: changes after one week chlorimipramine treatment.

H. Schoemaker, C. Benkelfat, H. Lôo, 1984, European journal of pharmacology.

Possible endocrine role of the pineal gland for 6-methoxytetrahydro-beta-carboline, a putative endogenous neuromodulator of the [3H]imipramine recognition site.

B. Winblad, H. Schoemaker, C. R. Lee, 1984, European journal of pharmacology.

Optimization of stereoselective ketone reduction by the white-rot fungus Merulius tremellosus ono991

H. Schoemaker, J. Field, A. Hage, 2001, Applied Microbiology and Biotechnology.

Reduction of aryl acids by white-rot fungi for the biocatalytic production of aryl aldehydes and alcohols

H. Schoemaker, J. Field, A. Hage, 1999, Applied Microbiology and Biotechnology.

Regioselective Hydrolysis of Carbohydrate Secondary Acyl Esters By Lipases

H. Schoemaker, E. Meijer, M. Kloosterman, 1990 .

Octa-O-Acetyl-Sucrose: Regioselective Deacetylations by Lipolytic Enzymes

H. Schoemaker, E. Meijer, M. Kloosterman, 1989 .

Xylose Isomerase Catalysed Novel Hexose Epimerization

H. Schoemaker, M. Leisola, O. Pastinen, 1999 .

RESOLUTION OF 2-AMINO-5-THIOMETHYL PENTANOIC ACID (HOMOMETHIONINE) WITH AMINOPEPTIDASE FROM PSEUDOMONAS-PUTIDA OR CHIRAL PHOSPHORIC-ACIDS

H. Schoemaker, H. Wynberg, Bindert K. Vriesema, 1986 .

Intramolecular Staudinger ligation: a powerful ring-closure method to form medium-sized lactams.

Wim J. N. Meester, H. Schoemaker, J. V. van Maarseveen, 2003, Angewandte Chemie.

A pincer auxiliary to force difficult lactamisations.

H. Schoemaker, J. V. van Maarseveen, H. Hiemstra, 2003, Organic & biomolecular chemistry.

Diastereoselective Synthesis of Medium-Sized Lactones by Cu(bpy)CI Catalyzed Cyclization of Trichloroacetates

H. Schoemaker, B. Kaptein, H. Hiemstra, 1993 .

Synthesis of medium-sized lactones by the copper(I)chloride/2,2'-bipyridine-catalyzed cyclization of di- and trichloroacetates

H. Schoemaker, B. Kaptein, H. Hiemstra, 1994 .

Synthesis of Enantiopure (S)-Indolylglycine by Organocatalyzed Friedel–Crafts Alkylation of Indole

H. Schoemaker, R. Gelder, H. Hiemstra, 2008 .

Differences in the temperature dependence of drug interaction with the noradrenaline and serotonin transporters

H. Schoemaker, S. Z. Langer, A. Segonzac, 1989, Neuropharmacology.

Synthetic Applications of Aliphatic Unsaturated α-H-α-Amino Acids.

H. Schoemaker, F. Rutjes, F. L. Delft, 2006 .

Amino Alcohol Coordination in Ruthenium(II)-Catalysed Asymmetric Transfer Hydrogenation of Ketones

H. Schoemaker, K. Goubitz, P. V. Leeuwen, 1999 .

A cross-metathesis route to functionalized α-methyl α-substituted amino acids

H. Schoemaker, B. Kaptein, Q. Broxterman, 2007 .

Discriminative Stimulus Effects of Drugs Acting at GABAA Receptors Differential Profiles and Receptor Selectivity

G. Perrault, D. Sanger, H. Schoemaker, 1999, Pharmacology Biochemistry and Behavior.

Efficient Enzymic Production of Enantiomerically Pure Amino Acids

H. Schoemaker, J. A. M. V. Balken, E. Meijer, 1986 .

Molecular and Pharmacological Characterization of Native Cortical γ-Aminobutyric AcidA Receptors Containing Both α1 and α3 Subunits*

H. Schoemaker, J. Bénavidès, D. Ruano, 1996, The Journal of Biological Chemistry.

Calcium Channel Receptor Binding Studies for Diltiazem and Its Major Metabolites: Functional Correlation to Inhibition of Portal Vein Myogenic Activity

H. Schoemaker, S. Z. Langer, P. Hicks, 1987, Journal of cardiovascular pharmacology.

Palladium-catalyzed allylation of α-hydroxy acids

H. Schoemaker, B. Kaptein, H. Moorlag, 2010 .

Enzymatic hydrolysis of cyanohydrins with recombinant nitrile hydratase and amidase from hodococcus erythropolis

H. Schoemaker, A. Glieder, H. Schwab, 2004, Biotechnology Letters.

Specific high-affinity saturable binding of [3H] R05-4864 to benzodiazepine binding sites in the rat cerebral cortex.

H. Schoemaker, H. Yamamura, M. Bliss, 1981, European journal of pharmacology.

Effect of chronic ethanol consumption on central and peripheral type benzodiazepine binding sites in the mouse brain

H. Schoemaker, Thomas L. Smith, H. Yamamura, 1983, Brain Research.

Presynaptic Sites of Antidepressant Action: Monoamine Transport Systems and Release-Modulating Autoreceptors

H. Schoemaker, S. Z. Langer, 1989 .

High-Affinity Binding of Antidepressants to Platelets and Brain Tissues

H. Schoemaker, S. Z. Langer, 1988 .

[3H]desipramine labels with high affinity the neuronal transporter for adrenaline in the frog heart.

H. Schoemaker, S. Z. Langer, C. Pimoule, 1987, European journal of pharmacology.

In vivo and in vitro interaction of the novel selective histamine H1 receptor antagonist mizolastine with H1 receptors in the rodent.

H. Schoemaker, Y. Claustre, J. Bénavidès, 1995, Arzneimittel-Forschung.

Laccase‐Mediated Deprotection of para‐Methoxyphenyl (PMP)‐Protected Amines

H. Schoemaker, F. Rutjes, J. Verkade, 2007 .

Vanadium containing bromoperoxidase: An example of an oxidoreductase with high operational stability in aqueous and organic media

H. Schoemaker, M. Franssen, R. Wever, 1987, Biotechnology and bioengineering.

5‐Methoxytryptoline, a Competitive Endocoid Acting at [3H]Imipramine Recognition Sites in Human Platelets

H. Schoemaker, S. Z. Langer, A. Segonzac, 1985, Journal of neurochemistry.

Effects of des-tyr1 -γ-endorphin on dopamine release from various rat brain regions in vitro

H. Schoemaker, V. Nickolson, 1980 .

Synthesis and benzodiazepine receptor (ω receptor) affinities of 3-substituted derivatives of pyrrolo[2,3-c]pyridine-5-carboxylate, a novel class of ω1 selective ligands

H. Schoemaker, Sunil Singh, P. Potier, 1999 .

INDUSTRIAL USE OF ENZYMES

H. Schoemaker, O. Turunen, M. Leisola, 2011 .

SL 81.0385: A novel selective and potent serotonin uptake inhibitor

H. Schoemaker, Y. Claustre, B. Scatton, 1988 .

N,N-acetals as N-acyliminium ion precursors: synthesis and absolute stereochemistry of epiquinamide.

H. Schoemaker, J. Daly, F. Rutjes, 2008, Organic letters.

Total synthesis of (+)-epiquinamide.

H. Schoemaker, F. Rutjes, R. Wijtmans, 2005, Organic letters.

A novel strategy for the synthesis of medium-sized lactams.

H. Schoemaker, J. V. van Maarseveen, H. Hiemstra, 2002, Organic letters.

Synthesis of Versatile Building Blocks through Asymmetric Hydrogenation of Functionalized Itaconic Acid Mono-Esters

H. Schoemaker, F. Rutjes, F. L. Delft, 2008 .

Enantioselective Sulfoxidation Catalyzed by Vanadium Haloperoxidases.

H. Schoemaker, H. Dekker, R. Wever, 1998, Inorganic chemistry.

Probing the scope of the sulfoxidation activity of vanadium bromoperoxidase from Ascophyllum nodosum

H. Schoemaker, R. Wever, H. Holland, 1999 .

Sulfoxidation mechanism of vanadium bromoperoxidase from Ascophyllum nodosum. Evidence for direct oxygen transfer catalysis.

H. Schoemaker, R. Wever, H. B. ten Brink, 2001, European journal of biochemistry.

Transition metal-catalyzed synthesis of novel biologically relevant tryptophan analogues

H. Schoemaker, F. Rutjes, F. L. Delft, 2004 .

Scope and limitations of the solution and solid phase synthesis of homoallylic amines via N-acyliminium ion reactions

Wim J. N. Meester, H. Schoemaker, F. Rutjes, 2004 .

Selective azetidine and tetrahydropyridine formation via Pd-catalyzed cyclizations of allene-substituted amines and amino acids.

H. Schoemaker, F. Rutjes, H. Hiemstra, 1999, Organic letters.

Diastereoselective synthesis of (2S,5R)-5-hydroxypipecolic acid and 6-substituted derivatives.

H. Schoemaker, Q. Broxterman, F. Rutjes, 2004, Organic letters.

A stereodivergent approach to substituted 4-hydroxypiperidines.

H. Schoemaker, F. Rutjes, J. Luten, 2002, The Journal of organic chemistry.

Complementary chemoenzymatic routes to both enantiomers of febrifugine.

H. Schoemaker, F. Rutjes, F. V. van Delft, 2009, Organic & biomolecular chemistry.

Amidopalladation of alkoxyallenes applied in the synthesis of an enantiopure 1-ethylquinolizidine frog alkaloid.

H. Schoemaker, F. Rutjes, J. V. van Maarseveen, 2004, Journal of the American Chemical Society.

A ring-closing metathesis-mediated route to novel enantiopure conformationally restricted cyclic amino acids †

H. Schoemaker, F. Rutjes, H. Hiemstra, 2000 .

Enantiopure Cα-tetrasubstituted α-amino acids. Chemo-enzymatic synthesis and application to turn-forming peptides

Claudio Toniolo, Floris P. J. T. Rutjes, Quirinus B. Broxterman, 2001 .

C-C Bond Formation via N-Phosphoryliminium Ions

H. Schoemaker, F. Rutjes, H. Hiemstra, 2004 .

Synthesis of optically pure .alpha.-alkylated .alpha.-amino acids and a single-step method for enantiomeric excess determination

H. Schoemaker, J. Kamphuis, R. Kellogg, 1988 .

Ring-closing metathesis of allylic O,O- and N,O-acetals.

H. Schoemaker, F. Rutjes, H. Hiemstra, 2002 .

Oxazaborolidine catalyzed enantioselective reductions of cyclic meso-imides

H. Schoemaker, B. Kaptein, R. Romagnoli, 1994 .

A Novel Transition Metal-Catalyzed Route to Functionalized Dihydropyrans and Tetrahydrooxepines

H. Schoemaker, F. Rutjes, H. Hiemstra, 1998 .

Lewis-acid-induced reactions of α-methoxyglycinamide derivatives with silyl enol ethers. Formation of 3-amino-2-pyrrolidinones and 3-amino-2-pyrrolinones

H. Schoemaker, B. Kaptein, J. Kamphuis, 1992 .

Biomimetic α-acylimmonium cyclisations of unactivated olefin

H. Schoemaker, W. N. Speckamp, J. Dijkink, 1978 .

Biomimetic heterocyclisations reactivity of rigid unsaturated systems

H. Schoemaker, W. N. Speckamp, J. Dijkink, 1975 .

New Developments in the Synthesis of Natural and Unnatural Amino Acids

H. Schoemaker, T. Sonke, J. Kamphuis, 1992, Annals of the New York Academy of Sciences.

Asymmetric reduction of ketones via whole cell bioconversions and transfer hydrogenation: complementary approaches

Ron Wever, Joost N. H. Reek, Paul C. J. Kamer, 2001 .

IR spectroscopy as a high-throughput screening-technique for enantioselective hydrogen-transfer catalysts

H. Schoemaker, J. Reek, P. V. Leeuwen, 2000 .

Novel Reductive Amination of Nitriles: An Efficient Route to 5-Hydroxypiperidone-Derived N,N-Acetals

H. Schoemaker, F. Rutjes, H. Hiemstra, 2003 .

Ring-closing metathesis of allylic O,O- and N,O-acetals.

H. Schoemaker, F. Rutjes, H. Hiemstra, 2002 .

Synthesis of Enantiomerically Pure Eight- and Nine-Membered Lactones by Copper(I) Chloride/2,2’-Bipyridine-Catalyzed Cyclization

H. Schoemaker, B. Kaptein, H. Hiemstra, 1995 .

Synthesis of medium-sized lactones by copper(I) catalyzed atom transfer cyclization

H. Schoemaker, B. Kaptein, H. Hiemstra, 1992 .

Intramolecular Staudinger ligation towards biaryl-containing lactams

H. Schoemaker, H. Hiemstra, G. Masson, 2006 .

Acetylene cyclisations of α-acylimmonium ions efficient synthesis of bridgehead nitrogen bicyclic ketones

H. Schoemaker, W. Speckamp, J. Dijkink, 1977 .

Biological Relevance and Synthesis of C-substituted Morpholine derivatives

H. Schoemaker, F. Rutjes, F. L. Delft, 2004 .

Total Synthesis of (+)‐Epiquinamide.

H. Schoemaker, F. Rutjes, R. Wijtmans, 2006 .

A Biocatalytic Route to Enantiomerically Pure Unsaturated α-H-α-Amino Acids

Floris P. J. T. Rutjes, Quirinus B. Broxterman, Theo Sonke, 2001 .

Large-Scale Synthesis of New Pyranoid Building Blocks Based on Aldolase-Catalysed Carbon-Carbon Bond Formation

Daniel Mink, Marcel Wubbolts, H. Schoemaker, 2008 .

Enantioselective high-performance liquid chromatographic separation of N-methyloxycarbonyl unsaturated amino acids on macrocyclic glycopeptide stationary phases.

H. Schoemaker, H. Hiemstra, A. Duchateau, 2006, Journal of chromatography. A.

Synthesis and structural analysis of a beta-hairpin peptide containing a sugar amino acid

H. Schoemaker, H. Overkleeft, G. Siegal, 2001 .

Linear oligopeptides. Part 316. Conformational characterization of syndiotactic homo-peptides from Cα,α-disubstituted glycines

H. Schoemaker, C. Toniolo, F. Formaggio, 1994 .

Peptides from chiral Cα,α-disubstituted glycines. Synthesis and conformational analysis of homochiral (αMe) Leu / Ala model peptides

H. Schoemaker, C. Toniolo, F. Formaggio, 2010 .

Peptides from chiral Cα,α-disubstituted glycines Synthesis and characterization, conformational energy computations and solution conformational analysis of Cα-methyl, Cα-isopropylglycine [(αMe)Val] derivatives and model peptides*

H. Schoemaker, C. Toniolo, M. Crisma, 2009 .

Onset of the fully extended conformation in (αMe)Leu derivatives and short peptides

H. Schoemaker, C. Toniolo, F. Formaggio, 1994 .

Position of side-chain branching and handedness of turns and helices of homopeptides from chiral Cα-methylated amino acids. Crystal-state structural analysis of (αMe)Leu trimer and tetramer

H. Schoemaker, C. Toniolo, F. Formaggio, 1994 .

Structural versatility of peptides from Cα, α‐disubstituted glycines: Crystal‐state conformational analysis of homopeptides from Cα‐methyl, Cα‐benzylglycine [(αMe)Phe]n

H. Schoemaker, C. Toniolo, F. Formaggio, 1993 .

Reverse Relationship between α-Carbon Chirality and Helix Handedness in (αMe)Phe Peptides

H. Schoemaker, C. Toniolo, F. Formaggio, 1993 .

Chemo-enzymatic synthesis of amino acids and derivatives

H. Schoemaker, B. Kaptein, T. Sonke, 1992 .

The p-Bromobenzamido Chromophore as a Circular Dichroic Probe for the Assignment of the Screw Sense of Helical Peptides.

H. Schoemaker, C. Toniolo, F. Formaggio, 1994 .

The preferred solid-state conformation of (alpha Me)Trp peptides.

H. Schoemaker, C. Toniolo, F. Formaggio, 2009, International journal of peptide and protein research.

Novel reactions of xylose isomerase from Streptomyces rubiginosus

H. Schoemaker, M. Leisola, O. Pastinen, 1999 .

C-2 Epimer Formation of Tetrose, Pentose and Hexose Sugars by Xylose Isomerase

H. Schoemaker, M. Leisola, A. Vuolanto, 2002 .

Resolution of methyl cis-3-chloromethyl-2-tetrahydrofurancarboxylate via enzymatic hydrolysis

H. Schoemaker, B. Kaptein, K. Goubitz, 1993 .

Evidence for direct oxygen transfer catalysis

H. Schoemaker, R. Wever, B. Hilda, 2001 .

Oxidation reactions catalyzed by vanadium chloroperoxidase from Curvularia inaequalis.

H. Schoemaker, H. Dekker, R. Wever, 2000, Journal of inorganic biochemistry.

Sodium dependent [3H]cocaine binding associated with dopamine uptake sites in the rat striatum and human putamen decrease after dopaminergic denervation and in Parkinsons disease

H. Schoemaker, B. Scatton, F. Javoy‐Agid, 1985, Naunyn-Schmiedeberg's Archives of Pharmacology.

5--Trig vs 6--Trig α-acyliminium ion-olefin cyclisations stereoselective synthesis of 7-(1-formyloxy-pent-1-yl)-1-aza-4-oxa-spiro[4.5]decane-2-ones

H. Schoemaker, W. Speckamp, C. Kruk, 1979 .

Phanerochaete chrysosporium: characterisation of ligninolytic enzymes and metabolism of veratryl alcohol

H. Schoemaker, M. Leisola, R. Waldner, 1987 .

Differences in presynaptic α-blockade, noradrenaline uptake inhibition, and potential antidepressant activity between (+)- and (-)mianserin

H. Schoemaker, H. Berendsen, V. Nickolson, 2004, Psychopharmacology.

Differential in vitro metabolism of β-endorphin in schizophrenia

H. Schoemaker, T. Davis, 1984, Peptides.

Characterization of in vitro proteolytic processing of β-endorphin by reversed-phase HPLC

H. Schoemaker, T. Davis, A. Culling-Berglund, 1984, Peptides.

Identification of β-endorphin-(6–17) as the principal metabolite of des-tyrosine-γ-endorphin (DTγE) in vitro and assessment of its activity in neurotransmitter receptor binding assays

N. Ling, H. Schoemaker, H. Yamamura, 1982 .

Dopamine Uptake by Rat Striatal Synaptosomes: Time‐and Temperature‐Dependent Decay and Protection by Dithiothreitol and Dopamine

H. Schoemaker, V. Nickolson, 1983, Journal of neurochemistry.

beta-Endorphin and its metabolites stimulate motility of the dog small intestine.

H. Schoemaker, J. Galligan, T. Davis, 1983, The Journal of pharmacology and experimental therapeutics.

A study of the metabolism of des-tyrosine-gamma-endorphin using an improved HPLC system.

H. Schoemaker, H. Yamamura, T. Davis, 1982, Psychopharmacology bulletin.

Specific regional differences of in vitro beta-endorphin metabolism in schizophrenics.

H. Schoemaker, T. Davis, A. Culling-Berglund, 1986, Life sciences.

High performance liquid chromatography of pharmacologically active amines and peptides in biological materials.

H. Schoemaker, H. Yamamura, T. Davis, 1982, Life sciences.

Effects of antidepressants on monoamine transporters

H. Schoemaker, S. Z. Langer, 1988, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Synthesis of a Naturally Occurring Diene‐Containing Amino Acid and Its Glutamyl Dipeptide via N‐Acyliminium Ion Chemistry

H. Schoemaker, T. Sonke, H. Hiemstra, 2008 .

Dopamine Uptake by Rat Striatal Synaptosomes: A Compartmental Analysis

H. Schoemaker, V. Nickolson, Hans Schoemaker, 1983, Journal of neurochemistry.

Pharmacological studies on synthetic flavonoids: comparison with diazepam

G. Perrault, D. Sanger, H. Schoemaker, 1999, Neuropharmacology.

Internal solvation, entropy, and energy effects on alternative channels for a single reaction. Methoxyl vs. methyl migration in the (M-methyl)+ ion from methoxymethyl isopropyl ether

R. Cooks, H. Schoemaker, N. Nibbering, 1975 .

New developments in the chemo-enzymatic production of amino acids.

H. Schoemaker, Q. Broxterman, J. Kamphuis, 1990, Advances in biochemical engineering/biotechnology.

Synthesis of γ,δ-unsaturated α-methyl-α-amino acids via coupling of allylsilanes with an α-methylglycine cation equivalent

H. Schoemaker, B. Kaptein, J. Kamphuis, 1992 .

Oxidative preparation of optically active n-hydroxy-α-amino acid amides

H. Schoemaker, J. Kamphuis, H. Ottenheijm, 1990 .

Catalytic N-Sulfonyliminium Ion-Mediated Cyclizations to α-Vinyl-Substituted Isoquinolines and β-Carbolines and Applications in Metathesis

H. Schoemaker, J. Maarseveen, S. S. Kinderman, 2005 .

Synthesis of .alpha.-substituted .alpha.-amino acids via cationic intermediates

H. Schoemaker, B. Kaptein, M. Brook, 1993 .

Peptides from chiral C alpha,alpha-disubstituted glycines. Crystallographic characterization of conformation of C alpha-methyl, C alpha-isopropylglycine [(alpha Me)Val] in simple derivatives and model peptides.

H. Schoemaker, C. Toniolo, M. Crisma, 2009, International journal of peptide and protein research.

N-Formylcarbamoylaspartame, a new aspartame-like sweetener. Synthesis and studies on stability and biological properties

H. Schoemaker, E. Meijer, D. Vries, 1991 .

Glutamatergic (N-Methyl-d-aspartate Receptor) Hypofrontality in Schizophrenia: Too Little Juice or a Miswired Brain?

Younglim Lee, H. Schoemaker, G. Marek, 2010, Molecular Pharmacology.

Stimulating neuroregeneration as a therapeutic drug approach for traumatic brain injury

H. Schoemaker, B. Mueller, R. Mueller, 2009, British journal of pharmacology.

[3H]8-OH-DPAT labels the serotonin transporter in the rat striatum.

H. Schoemaker, S. Z. Langer, 1986, European journal of pharmacology.

Alpha-adrenoceptor subtypes in blood vessels: physiology and pharmacology.

H. Schoemaker, H Schoemaker, S Z Langer, 1989, Clinical and experimental hypertension. Part A, Theory and practice.

Haloperidol-induced catalepsy is absent in dopamine D(2), but maintained in dopamine D(3) receptor knock-out mice.

R. Depoortère, G. Perrault, D. Sanger, 2000, European journal of pharmacology.

Conformationally restricted analogues of anti-aspartame-type sweeteners

H. Schoemaker, C. Toniolo, F. Formaggio, 1992 .

Production of natural and synthetic L- and D-amino acids by aminopeptidases and amino amidases

H. Schoemaker, B. Kaptein, Q. Broxterman, 1992 .

Use of Enzymes in the Synthesis of Amino Acids

H. Schoemaker, B. Kaptein, T. Sonke, 2010 .

On the interaction of lignin peroxidase with lignin

H. Schoemaker, K. Piontek, 1996 .

Ring‐Closing Metathesis on Solid Support: Elaboration of a Cyclization/Cleavage Strategy Towards Unsaturated α‐Ester‐Substituted N‐Heterocycles

G. M. Visser, H. Schoemaker, F. Rutjes, 1998 .

Development of disease-modifying treatment of schizophrenia.

H. Schoemaker, A. Bespalov, G. Gross, 2012, Handbook of experimental pharmacology.

SL651498, a GABAA receptor agonist with subtype-selective efficacy, as a potential treatment for generalized anxiety disorder and muscle spasms.

G. Perrault, H. Schoemaker, G. Griebel, 2003, CNS drug reviews.

SL651498: An Anxioselective Compound with Functional Selectivity for α2- and α3-Containing γ-Aminobutyric AcidA (GABAA) Receptors

G. Perrault, H. Schoemaker, G. Griebel, 2001 .

5HT-receptor antagonist properties of SCH 23390 in vascular smooth muscle and brain.

H. Schoemaker, S. Z. Langer, P. Hicks, 1984, European journal of pharmacology.

Generation and Therapeutic Efficacy of Highly Oligomer-Specific β-Amyloid Antibodies

H. Schoemaker, J. Sullivan, F. van Leuven, 2010, The Journal of Neuroscience.

Habituation Deficits Induced by Metabotropic Glutamate Receptors 2/3 Receptor Blockade in Mice: Reversal by Antipsychotic Drugs

H. Schoemaker, A. Jongen-Rêlo, A. Bespalov, 2007, Journal of Pharmacology and Experimental Therapeutics.

Amyloid β Oligomers (Aβ1–42 Globulomer) Suppress Spontaneous Synaptic Activity by Inhibition of P/Q-Type Calcium Currents

A. Draguhn, C. Bruehl, H. Schoemaker, 2008, The Journal of Neuroscience.

In vivo identification of calcium antagonist binding sites using [3H]nitrendipine.

H. Schoemaker, H. Yamamura, W. Roeske, 1983, European journal of pharmacology.

SSR181507, A Dopamine D2 Receptor Antagonist and 5-HT1A Receptor Agonist. I: Neurochemical and Electrophysiological Profile

H. Schoemaker, P. Soubrié, Y. Claustre, 2003, Neuropsychopharmacology.

New evidence that the pharmacological effects of benzodiazepine receptor ligands can be associated with activities at different BZ (ω) receptor subtypes

G. Perrault, D. Sanger, H. Schoemaker, 1999, Psychopharmacology.

Effects of Ca++ on [3H]diltiazem binding and its allosteric interaction with dihydropyridine calcium channel binding sites in the rat cortex.

H. Schoemaker, S. Z. Langer, 1989, The Journal of pharmacology and experimental therapeutics.

Stereocontrolled synthesis of functionalized 1-azaspirans

H. Schoemaker, W. N. Speckamp, 1980 .

Chemo-enzymatic synthesis of enantiomerically pure α-H and α-alkyl α-amino acids and derivatives

H. Schoemaker, J. Kamphuis, J. A. M. V. Balken, 1990 .

Stereocontrolled synthesis of functionalized 1-azaspirans : Efficient synthesis of perhydrohistrionicotoxin

H. Schoemaker, W. N. Speckamp, 1980 .

Targeting repulsive guidance molecule A to promote regeneration and neuroprotection in multiple sclerosis.

H. Schoemaker, P. Calabresi, H. Rus, 2015, Cell reports.

[3H]diltiazem binding to calcium channel antagonists recognition sites in rat cerebral cortex.

H. Schoemaker, H Schoemaker, S Z Langer, 1985, European journal of pharmacology.

Biocatalytic single-step alkene cleavage from aryl alkenes: an enzymatic equivalent to reductive ozonization.

G. Guebitz, H. Schoemaker, W. Kroutil, 2006, Angewandte Chemie.

Diltiazem enhancement of [3H]nitrendipine binding to calcium channel associated drug receptor sites in rat brain synaptosomes.

H. Schoemaker, R. Boles, H. Yamamura, 1982, Biochemical and biophysical research communications.

Alfuzosin, a selective alpha 1-adrenoceptor antagonist in the lower urinary tract.

H. Schoemaker, P. Manoury, J. Lechaire, 1993, British journal of pharmacology.

Binding of [3H]cirazoline to an imidazoline site in rat brain and kidney membranes.

H. Schoemaker, S. Z. Langer, I. Angel, 1995, European journal of pharmacology.

Specific high-affinity binding sites for [3H]Ro 5-4864 in rat brain and kidney.

H. Schoemaker, R. Boles, H. Yamamura, 1983, The Journal of pharmacology and experimental therapeutics.

Laser capture microdissection and microarray analysis of dividing neural progenitor cells from the adult rat hippocampus

H. Schoemaker, R. Loebbert, G. Gross, 2007, The European journal of neuroscience.

Binding of [3H]ifenprodil, a novel NMDA antagonist, to a polyamine-sensitive site in the rat cerebral cortex.

H. Schoemaker, S. Z. Langer, J. Allen, 1990, European journal of pharmacology.

Litoxetine: a selective 5-HT uptake inhibitor with concomitant 5-HT3 receptor antagonist and antiemetic properties.

H. Schoemaker, S. Z. Langer, I. Angel, 1993, European journal of pharmacology.

Amphetamine decreases behavioral inhibition by stimulation of dopamine D2, but not D3, receptors

H. Schoemaker, A. Jongen-Rêlo, M. V. van Gaalen, 2009, Behavioural pharmacology.

Synaptosomal uptake studies on recombinant inbred mice; neurotransmitter interaction and behavioral correlates

J. Crabbe, H. Schoemaker, V. Nickolson, 1982, Brain Research.

l-Selective Amidase with Extremely Broad Substrate Specificity from Ochrobactrum anthropi NCIMB 40321

H. Schoemaker, M. Wubbolts, B. Kaptein, 2005, Applied and Environmental Microbiology.

Benzodiazepine receptor binding in young, mature and senescent rat brain and kidney

H. Schoemaker, M. Morelli, T. Burks, 1981, Neurobiology of Aging.

Isolation and characterization of in vitro central beta-endorphin metabolism in schizophrenia.

H. Schoemaker, H. Yamamura, T. Davis, 1983, Proceedings of the Western Pharmacology Society.

Centrally acting drugs alter in vitro β-endorphin processing in the rat

H. Schoemaker, T. Davis, A. Culling, 1984 .

Inhibitors of GlyT1 Affect Glycine Transport via Discrete Binding Sites

H. Schoemaker, W. Amberg, M. Mezler, 2008, Molecular Pharmacology.

Bioactive and model peptides characterized by the helicogenic (αMe)Phe residue

H. Schoemaker, C. Toniolo, F. Formaggio, 1993 .

New aspartame-like sweeteners containing L-(αMe)Phe

H. Schoemaker, C. Toniolo, M. Crisma, 1992 .

Lignin degradation.

H. Schoemaker, M. Leisola, 1988, Trends in biochemical sciences.

Aminoamidase-Catalyzed Preparation and Further Transformations of Enantiopure α-Hydrogen- and α,α-Disubstituted α-Amino Acids

H. Schoemaker, C. Toniolo, F. Formaggio, 2001 .

Synthesis of (Optically Active) Sulfur‐Containing Trifunctional Amino Acids by Radical Addition to (Optically Active) Unsaturated Amino Acids.

H. Schoemaker, B. Kaptein, Q. Broxterman, 1993 .

Enantioselective Epoxidation and Carbon–Carbon Bond Cleavage Catalyzed by Coprinus cinereus Peroxidase and Myeloperoxidase*

H. Schoemaker, I. Kooter, R. Wever, 2000, The Journal of Biological Chemistry.

Resolution of 2-Amino-5-thiomethyl Pentanoic Acid (Homomethionine) with Aminopeptidase from Pseudomonas putida or Chiral Phosphoric Acids.

H. Schoemaker, H. Wynberg, E. Meijer, 1986 .

DSM Gets the Biocatalysis Bug

Q. B. Broxterman, W. H. J. Boesten, H. E. Schoemaker, 1998 .

Synthesis of Optically Pure α-Alkylated α-Amino Acids and a Single-Step Method for Enantiomeric Excess Determination.

H. Schoemaker, J. Kamphuis, E. Meijer, 1988 .

Synthesis of optically pure .alpha.-alkylated .alpha.-amino acids and a single-step method for enantiomeric excess determination [Erratum to document cited in CA108(19):166035p]

H. Schoemaker, J. Kamphuis, R. Kellogg, 1988 .

Preparation and use of enantiomerically pure Ca-tetrasubstituted a-amino acids

H. Schoemaker, C. Toniolo, F. Formaggio, 1996 .

Running wheel activity is sensitive to acute treatment with selective inhibitors for either serotonin or norepinephrine reuptake

H. Schoemaker, Martin Weber, G. Gross, 2009, Psychopharmacology.

Polyamines allosterically modulate [3H]nitrendipine binding to the voltage-sensitive calcium channel in rat brain.

H. Schoemaker, 1992, European journal of pharmacology.

Behavioral characterization of the mGlu group II/III receptor antagonist, LY-341495, in animal models of anxiety and depression.

H. Schoemaker, M. Mezler, I. Sukhotina, 2008, European journal of pharmacology.

[3H]SCH 23390 labeled D1 dopamine receptors are unchanged in schizophrenia and Parkinson's disease.

G. Reynolds, H. Schoemaker, S. Z. Langer, 1985, European journal of pharmacology.

Inhibition of Calpain Prevents N-Methyl-d-aspartate-Induced Degeneration of the Nucleus Basalis and Associated Behavioral Dysfunction

H. Schoemaker, K. Reymann, C. Nyakas, 2008, Journal of Pharmacology and Experimental Therapeutics.

Allosteric modulation by diltiazem and verapamil of [3H]nitrendipine binding to calcium channel sites in rat brain.

H. Schoemaker, R. Boles, H. Yamamura, 1983, Proceedings of the Western Pharmacology Society.

Langer et al. reply

H. Schoemaker, B. Scatton, W. Rein, 1998 .

Processing of beta-endorphin in the dog intestine: regional specificity.

H. Schoemaker, T. Burks, J. Galligan, 1983, Proceedings of the Western Pharmacology Society.

Isolation and characterization of in vitro endorphin metabolism in the brain.

H. Schoemaker, H. Yamamura, T. Davis, 1982, Proceedings of the Western Pharmacology Society.

A novel synthetic approach to perhydrohistrionicotoxin stereoselective synthesis of 1-aza-spiranes

H. Schoemaker, W. Speckamp, 1978 .

Establishment of a secondary screening assay for P/Q-type calcium channel blockers.

A. Draguhn, C. Bruehl, H. Schoemaker, 2013, Combinatorial chemistry & high throughput screening.

αMe)Val and (αMe)Phe peptides fold into turns and helices of opposite handedness

H. Schoemaker, C. Toniolo, F. Formaggio, 1993 .

Effects of a Positive Allosteric Modulator of Group II Metabotropic Glutamate Receptors, LY487379, on Cognitive Flexibility and Impulsive-Like Responding in Rats

H. Schoemaker, G. Marek, P. Popik, 2010, Journal of Pharmacology and Experimental Therapeutics.

Amisulpride: from animal pharmacology to therapeutic action

G. Perrault, D. Sanger, H. Schoemaker, 1997, International clinical psychopharmacology.

Complex allosteric modulation of the binding of the NMDA receptor antagonist [3H]CGP39653.

H. Schoemaker, A. Oblin, 1994, European journal of pharmacology.

Synthesis of Dipeptides Containing α-Substituted Amino Acids; Their Use as Chiral Ligands in Lewis Acid Catalyzed Reactions.

H. Schoemaker, B. Kaptein, Q. Broxterman, 1995 .

Calpain inhibition prevents amyloid-β-induced neurodegeneration and associated behavioral dysfunction in rats

H. Schoemaker, C. Nyakas, P. Luiten, 2010, Neuropharmacology.

Backbone modified formyl-methionyl tripeptide chemoattractants

H. Schoemaker, C. Toniolo, F. Formaggio, 1993 .

Determination of the enantiomers of α-H-α-amino acids, α-alkyl-α-amino acids and the corresponding acid amides by high-performance liquid chromatography☆

H. Schoemaker, J. Kamphuis, E. Meijer, 1989 .

Nitrile hydrolysis activity of Rhodococcus erythropolis NCIMB 11540 whole cells.

H. Schoemaker, H. Schwab, F. Rutjes, 2006, Biotechnology journal.

University of Groningen Calpain inhibition prevents amyloid-beta-induced neurodegeneration and associated behavioral dysfunction in rats Granic,

H. Schoemaker, C. Nyakas, P. Luiten, 2010 .

SL 85.0324: a novel benzimidazole derivative with selective histamine H1-receptor antagonist properties

H. Schoemaker, Y. Claustre, B. Scatton, 1990 .

A β‐amyloid oligomer directly modulates P/Q‐type calcium currents in Xenopus oocytes

H. Schoemaker, M. Mezler, V. Nimmrich, 2012, British journal of pharmacology.

Pharmacological characterisation and autoradiographic distribution of polyamine-sensitive [3H]ifenprodil binding sites in the rat brain

H. Schoemaker, B. Scatton, C. Dana, 1991, Neuroscience Letters.

[3H]7-OH-DPAT labels both dopamine D3 receptors and σ sites in the bovine caudate nucleus

H. Schoemaker, 1993 .

Inhibition of calpain prevents NMDA‐induced cell death and β‐amyloid‐induced synaptic dysfunction in hippocampal slice cultures

H. Schoemaker, M. Strassburger, V. Nimmrich, 2010, British journal of pharmacology.

RESEARCH PAPER Inhibition of calpain prevents NMDA-induced cell death and b-amyloid-induced synaptic dysfunction in hippocampal slice cultures

H. Schoemaker, K. Reymann, M. Strassburger, 2010 .

Tryptamine, a Substrate for the Serotonin Transporter in Human Platelets, Modifies the Dissociation Kinetics of [3H]Imipramine Binding: Possible Allosteric Interaction

H. Schoemaker, S. Z. Langer, R. Raisman, 1985, Journal of neurochemistry.

Ifenprodil and Eliprodil: Neuroprotective NMDA Receptor Antagonists and Calcium Channel Blockers

G. Perrault, D. Sanger, H. Schoemaker, 1997 .

Glyoxylates as Versatile Building Blocks for the Synthesis of α-Amino Acid and α-Alkoxy Acid Derivatives via Cationic Intermediates

Wim J. N. Meester, H. Schoemaker, F. Rutjes, 2003 .

The effect of crown ethers on enzyme-catalysed reactions in organic solvents

D. Reinhoudt, W. Verboom, H. Schoemaker, 1989 .

Enzymatic enantioselective C-C-bond formation in microreactors.

J C M van Hest, H. Schoemaker, J. V. van Hest, 2008, Biotechnology and bioengineering.

Interaction between dopamine influx and efflux in rat striatal synaptosomes.

H. Schoemaker, V. Nickolson, 1982, Life sciences.

Short-term lithium administration to healthy volunteers produces long-lasting pronounced changes in platelet serotonin uptake but not imipramine binding

H. Schoemaker, H. Lôo, A. Galzin, 2004, Psychopharmacology.

SL651498: an anxioselective compound with functional selectivity for alpha2- and alpha3-containing gamma-aminobutyric acid(A) (GABA(A)) receptors.

G. Perrault, H. Schoemaker, G. Griebel, 2001, Journal of Pharmacology and Experimental Therapeutics.