D. Vetrie

发表

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

William Stafford Noble, Nancy R. Zhang, Stephen C. J. Parker, 2007, Nature.

Requirement of bic/microRNA-155 for Normal Immune Function

Anton J. Enright, A. Enright, D. Vetrie, 2007, Science.

The ENCODE (ENCyclopedia Of DNA Elements) Project

Paul T. Groth, William Stafford Noble, Colin N. Dewey, 2004, Science.

The landscape of histone modifications across 1% of the human genome in five human cell lines.

Shane C. Dillon, E. Birney, Z. Weng, 2007, Genome research.

A 6.5-Mb yeast artificial chromosome contig incorporating 33 DNA markers on the human X chromosome at Xq22.

D. Bentley, D. Vetrie, H. Lehrach, 1994, Genomics.

The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases

D. Bentley, D. Vetrie, R. Levinsky, 1993, Nature.

DNA microarrays for comparative genomic hybridization based on DOP‐PCR amplification of BAC and PAC clones

N. Carter, H. Fiegler, D. Vetrie, 2003, Genes, chromosomes & cancer.

Complex Exon-Intron Marking by Histone Modifications Is Not Determined Solely by Nucleosome Distribution

Peter Saffrey, Ian Dunham, Cordelia Langford, 2010, PloS one.

Dual targeting of p53 and c-Myc selectively eliminates leukaemic stem cells

Karen Dunn, Andrew Pierce, Koorosh Korfi, 2016, Nature.

Epigenetic dysregulation in chronic myeloid leukaemia: A myriad of mechanisms and therapeutic options.

D. Vetrie, S. Koschmieder, 2017, Seminars in cancer biology.

Position effect on PLP1 may cause a subset of Pelizaeus-Merzbacher disease symptoms

D. Vetrie, C. Catsman-Berrevoets, G. Rappold, 2004, Journal of Medical Genetics.

Structural basis for chromosome X-linked agammaglobulinemia: a tyrosine kinase disease.

J. Sowadski, D. Vetrie, M. Vihinen, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Genomic Approaches Uncover Increasing Complexities in the Regulatory Landscape at the Human SCL (TAL1) Locus

Shane C. Dillon, C. Langford, R. Andrews, 2010, PloS one.

A complete YAC contig and cosmid interval map covering the entirety of human Xq21.33 to Xq22.3 from DXS3 to DXS287.

D. Vetrie, E. Kendall, W. Evans, 1997, Genomics.

Isolation of cDNA clones mapping around DXS178: a search for human X-linked agammaglobulinaemia gene using yeast artificial chromosomes, cosmids and direct cDNA selection.

D. Bentley, I. Dunham, D. Vetrie, 1993, Immunodeficiency.

Structural instability of human tandemly repeated DNA sequences cloned in yeast artificial chromosome vectors.

C. Tyler-Smith, D. Vetrie, A. Villasanté, 1990, Nucleic acids research.

Gene expression profiling in polycythemia vera using cDNA microarray technology.

C. Langford, D. Vetrie, J. Boultwood, 2003, Cancer research.

Tyrosine Kinase Inhibitor Independent Gene Expression Signature in CML Offers New Targets for LSPC Eradication Therapy

D. Vetrie, M. Copland, T. Holyoake, 2022, bioRxiv.

CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression.

D. Vetrie, T. Holyoake, F. Pellicanò, 2017, Blood.

Localization of the novel serine/threonine protein phosphatase 6 gene (PPP6C) to human chromosome Xq22.3.

D. Vetrie, P. Lichter, S. Joos, 1997, Genomics.

Gene Expression Profiling in Polycythemia Vera Using cDNA Microarray Technology 1

C. Langford, D. Vetrie, J. Boultwood, 2003 .

Somatic mosaicism associated with a mild Alport syndrome phenotype

D. Vetrie, P. Green, F. Flinter, 2000, Journal of medical genetics.

X inactivation patterns in females with Alport's syndrome: a means of selecting against a deleterious gene?

D. Vetrie, M. Bobrow, A. Harris, 1992, Journal of medical genetics.

Major rearrangements in the α5(IV) collagen gene in three patients with alport syndrome

D. Vetrie, M. Bobrow, A. Harris, 1991 .

Identification of Btk mutations in 20 unrelated patients with X-linked agammaglobulinaemia (XLA).

D. Vetrie, M. Vihinen, M. Bobrow, 1995, Human molecular genetics.

Exon array CGH: detection of copy-number changes at the resolution of individual exons in the human genome.

R. Andrews, P. Dhami, D. Vetrie, 2005, American journal of human genetics.

Mapping and characterization of the X-linked dyskeratosis congenita (DKC) gene.

D. Vetrie, S. Hassock, F. Giannelli, 1999, Genomics.

Characterization of DRP2, a novel human dystrophin homologue

Q. Bone, D. Vetrie, C. Shaw-Smith, 1996, Nature Genetics.

Expression profiling of the Leishmania life cycle: cDNA arrays identify developmentally regulated genes present but not annotated in the genome.

D. Vetrie, M. Levick, J. Blackwell, 2004, Molecular and biochemical parasitology.

Functional diversity for REST (NRSF) is defined by in vivo binding affinity hierarchies at the DNA sequence level.

Paul Flicek, Ian Dunham, Shane C. Dillon, 2009, Genome research.

Identifying gene regulatory elements by genomic microarray mapping of DNaseI hypersensitive sites.

Shane C. Dillon, P. Campbell, I. Dunham, 2006, Genome research.

Gene expression profiling in the myelodysplastic syndromes using cDNA microarray technology

C. Langford, D. Vetrie, J. Cavenagh, 2004, British journal of haematology.

Epigenetic Reprogramming Sensitizes CML Stem Cells to Combined EZH2 and Tyrosine Kinase Inhibition.

D. Vetrie, A. Hamilton, T. Holyoake, 2016, Cancer discovery.

Physical mapping shows close linkage between the α-galactosidase A gene (GLA) and the DXS178 locus

D. Bentley, D. Vetrie, M. Bobrow, 1993, Human Genetics.

Chromatin looping defines expression of TAL1, its flanking genes, and regulation in T-ALL.

D. Vetrie, Yan Zhou, A. West, 2013, Blood.

regulation in TALL , its flanking genes and TAL 1 Chromatin looping defines expression

D. Vetrie, Yan Zhou, A. West, 2013 .

Epigenetic Reprogramming and Emerging Epigenetic Therapies in CML

D. Vetrie, M. Scott, Ross Kinstrie, 2019, Front. Cell Dev. Biol..

Identification of novel deletion breakpoints bordered by segmental duplications in the NF1 locus using high resolution array-CGH

L. Bolund, D. Vetrie, A. Piotrowski, 2005, Journal of Medical Genetics.

Applications of genomic microarrays to explore human chromosome structure and function.

N. Carter, D. Vetrie, 2004, Human molecular genetics.

The leukaemia stem cell: similarities, differences and clinical prospects in CML and AML

D. Vetrie, M. Copland, G. Helgason, 2020, Nature Reviews Cancer.

The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases

D. Vetrie, D. Vetrie, 1993, Nature.

The leukaemia stem cell: similarities, differences and clinical prospects in CML and AML

D. Vetrie, M. Copland, G. Helgason, 2020, Nature Reviews Cancer.

Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays.

Jan Komorowski, Ian Dunham, Kenneth Wester, 2005, Human molecular genetics.

A novel X–linked gene, DDP, shows mutations in families with deafness (DFN–1), dystonia, mental deficiency and blindness

D. Vetrie, R. Stevenson, C. Schwartz, 1996, Nature Genetics.

Autosomal-dominant microtia linked to five tandem copies of a copy-number-variable region at chromosome 4p16.

N. Carter, H. Fiegler, D. Vetrie, 2008, American Journal of Human Genetics.

Long-range mapping of the gene for the human α5(IV) collagen chain at Xq22–q23

D. Vetrie, M. Bobrow, A. Harris, 1992 .

Pelizaeus-Merzbacher disease: identification of Xq22 proteolipid-protein duplications and characterization of breakpoints by interphase FISH.

D. Vetrie, K. Woodward, S. Malcolm, 1998, American journal of human genetics.

ULK1 inhibition promotes oxidative stress–induced differentiation and sensitizes leukemic stem cells to targeted therapy

D. Vetrie, M. Copland, M. Scott, 2021, Science Translational Medicine.

Identification of deletions in thebtk gene allows unambiguous assessment of carrier status in families with X-linked agammaglobulinaemia

D. Bentley, D. Vetrie, R. Lovering, 1994, Human Genetics.

Whole-genome microarrays of fission yeast: characteristics, accuracy, reproducibility, and processing of array data

Jürg Bähler, Gabriella Rustici, Juan Mata, 2003, BMC Genomics.

A KDM4A-PAF1-mediated epigenomic network is essential for acute myeloid leukemia cell self-renewal and survival

D. Vetrie, Xu Huang, S. Marmiroli, 2020, Cell Death & Disease.

Identification of genetic aberrations on chromosome 22 outside the NF2 locus in schwannomatosis and neurofibromatosis type 2

L. Bolund, D. Vetrie, I. Ernberg, 2005, Human mutation.

DNA rearrangements in the α5(IV) collagen gene (COL4A5) of individuals with alport syndrome: Further refinement using pulsed-field gel electrophoresis

D. Vetrie, M. Bobrow, A. Harris, 1992 .

The Spliceosome: A New Therapeutic Target in Chronic Myeloid Leukaemia

D. Vetrie, P. Cony-Makhoul, M. Copland, 2022, Cancers.

Construction of a yeast artificial chromosome contig encompassing the human alpha 5(IV) collagen gene (COL4A5).

D. Vetrie, M. Bobrow, A. Harris, 1992, Genomics.

The chronic myeloid leukemia stem cell: stemming the tide of persistence.

D. Vetrie, T. Holyoake, 2017, Blood.

From genomes to vaccines: Leishmania as a model.

J. Vilo, D. Vetrie, M. Levick, 2002, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Cancer: Repositioned to kill stem cells

D. Vetrie, T. Holyoake, 2015, Nature.

The human family of Deafness/Dystonia peptide (DDP) related mitochondrial import proteins.

D. Vetrie, E. Kendall, T. Freeman, 1999, Genomics.

BTK, A Novel Protein Tyrosine Kinase Mutated in X-Linked Agammaglobulinemia

D. Vetrie, I. Vořechovský, C. I. Smith, 1994 .

X inactivation as a mechanism of selection against lethal alleles: further investigation of incontinentia pigmenti and X linked lymphoproliferative disease.

C. Cole, D. Vetrie, M. Bobrow, 1992, Journal of medical genetics.

lymphoproliferative disease . incontinentia pigmenti and X linked against lethal alleles : further investigation of X inactivation as a mechanism of selection

C. Cole, D. Vetrie, M. Bobrow, 2022 .

The Implications of the Cloning of the XLA Gene

D. Vetrie, M. Bobrow, F. Flinter, 1993, Journal of the Royal College of Physicians of London.

Isolation of the defective gene in X linked agammaglobulinaemia.

D. Vetrie, 1993, Journal of medical genetics.

Sequence and chromosomal location of a human homologue of LRPR1, an FSH primary response gene.

D. Vetrie, M. Bobrow, E. Kendall, 1996, Genomics.

Isolation of cosmid and cDNA clones in the region surrounding the BTK gene at Xq21.3-q22.

D. Bentley, D. Vetrie, L. Notarangelo, 1994, Genomics.

Pillars Article: The Gene Involved in X-linked Agammaglobulinaemia Is a Member of the Src Family of Protein-Tyrosine Kinases. Nature. 1993. 361: 226–233

Christine Kinnon, Frances Flinter, David R. Bentley, 2012 .

Molecular diagnosis of X-linked agammaglobulinaemia

D. Vetrie, L. Hammarström, J. Björkander, 1993, The Lancet.

Detection of mutations in COL4A5 in patients with Alport Syndrome

D. Vetrie, F. Flinter, K. Plant, 1999, Human mutation.

Notch Pathway Activation Targets Leukemic Stem Cells in Chronic-Phase Chronic Myeloid Leukemia (CP-CML)

D. Vetrie, M. Copland, T. Holyoake, 2016 .

Cancer: Repositioned to kill stem cells

D. Vetrie, T. Holyoake, 2015, Nature.

Activating p53 abolishes self-renewal of quiescent leukaemic stem cells in residual CML disease

D. Vetrie, M. Copland, M. Drotar, 2024, Nature communications.

Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche

D. Vetrie, M. Copland, L. Hopcroft, 2024, Nature communications.