S. Park

发表

Nrg1 Is a Transcriptional Repressor for Glucose Repression of STA1 Gene Expression inSaccharomyces cerevisiae

S. Park, S. S. Koh, J. Chun, 1999, Molecular and Cellular Biology.

Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes

S. Park, S. Nakae, T. Sumida, 2014, EMBO Molecular Medicine.

Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes

S. Park, S. Nakae, T. Sumida, 2013, EMBO molecular medicine.

Jun activation domain-binding protein 1 is required for mitotic checkpoint activation via its involvement in hyperphosphorylation of 53BP1

S. Park, H. Yoo, H. Kwak, 2005, Journal of Cancer Research and Clinical Oncology.

Smad6-specific recruitment of Smurf E3 ligases mediates TGF-β1-induced degradation of MyD88 in TLR4 signalling.

S. Park, Seong-Jin Kim, Su Myung Jung, 2011, Nature communications.

Etoposide-induced Smad6 expression is required for the G1 to S phase transition of the cell cycle in CMT-93 mouse intestinal epithelial cells

S. Park, E. K. Lee, I. Han, 2008, Experimental & Molecular Medicine.

Pellino-1, an adaptor protein of interleukin-1 receptor/toll-like receptor signaling, is sumoylated by Ubc9

S. Park, C. Choi, J. Kwon, 2011, Molecules and cells.

The Deubiquitinating Enzyme USP20 Regulates the TNFα-Induced NF-κB Signaling Pathway through Stabilization of p62

S. Park, Jaewon Lee, Dongyeob Seo, 2020, International journal of molecular sciences.

IN-1130, a novel transforming growth factor-beta type I receptor kinase (activin receptor-like kinase 5) inhibitor, promotes regression of fibrotic plaque and corrects penile curvature in a rat model of Peyronie's disease.

S. Park, Seong-Jin Kim, J. Han, 2009, The journal of sexual medicine.

Smad7 and Smad6 bind to discrete regions of Pellino-1 via their MH2 domains to mediate TGF-beta1-induced negative regulation of IL-1R/TLR signaling.

S. Park, Seong-Jin Kim, J. Kwon, 2010, Biochemical and biophysical research communications.

Genetic alterations of the TGF-beta signaling pathway in colorectal cancer cell lines: a novel mutation in Smad3 associated with the inactivation of TGF-beta-induced transcriptional activation.

S. Park, J. Ku, K. Yoon, 2007, Cancer letters.

Angiopoietin-like protein 2, a chronic inflammatory mediator, is a new target induced by TGF-β1 through a Smad3-dependent mechanism.

S. Park, R. Martinus, Jun Hwan Kim, 2013, Biochemical and biophysical research communications.

Role of increased penile expression of transforming growth factor-beta1 and activation of the Smad signaling pathway in erectile dysfunction in streptozotocin-induced diabetic rats.

S. Park, Seong-Jin Kim, S. Song, 2008, The journal of sexual medicine.

The hepatitis B virus encoded oncoprotein pX amplifies TGF- (cid:1) family signaling through direct interaction with Smad4: potential mechanism of hepatitis B virus-induced liver fibrosis

S. Park, A. Roberts, M. Caestecker, 2001 .

SMAD3 Determines Conventional versus Plasmacytoid Dendritic Cell Fates

S. Park, K. Miyazawa, S. Nakae, 2019, bioRxiv.

Inhibition of erythropoiesis by Smad6 in human cord blood hematopoietic stem cells.

S. Park, Jeong-Hwan Yoon, M. Mamura, 2012, Biochemical and biophysical research communications.

PTEN suppresses hyaluronic acid-induced matrix metalloproteinase-9 expression in U87MG glioblastoma cells through focal adhesion kinase dephosphorylation.

S. Park, C. Rhee, I. Park, 2002, Cancer research.

S1219 residue of 53BP1 is phosphorylated by ATM kinase upon DNA damage and required for proper execution of DNA damage response.

S. Park, H. Kwak, Chang-Hun Lee, 2009, Biochemical and biophysical research communications.

A Reciprocal Role of the Smad4‐Taz Axis in Osteogenesis and Adipogenesis of Mesenchymal Stem Cells

S. Park, Jaewon Lee, No-Joon Song, 2018, Stem cells.

14-3-3ɛ protein increases matrix metalloproteinase-2 gene expression via p38 MAPK signaling in NIH3T3 fibroblast cells

S. Park, C. Choi, E. K. Lee, 2009, Experimental & Molecular Medicine.

The deubiquitinating enzyme USP20 stabilizes ULK1 and promotes autophagy initiation

S. Park, C. Choi, Jungwon Choi, 2018, EMBO reports.

Fine tuning and cross-talking of TGF-beta signal by inhibitory Smads.

S. Park, 2005, Journal of biochemistry and molecular biology.

Effect of bone morphogenetic protein‐6 on macrophages

S. Park, Seong-Jin Kim, J. Hong, 2009, Immunology.

Serum amyloid A promotes emphysema by triggering the reciprocal activation of neutrophils and ILC3s

S. Park, S. Choi, D. Chung, 2021, Clinical and translational medicine.

Inhibition of lethal inflammatory responses through the targeting of membrane-associated Toll-like receptor 4 signaling complexes with a Smad6-derived peptide

S. Park, Seong-Jin Kim, K. Jung, 2015, EMBO molecular medicine.

Human Breast Cancer Cells Type II Receptor Expression in β Transforming Growth Factor MS-275 , A Histone Deacetylase Inhibitor , Selectively Induces Updated

S. Park, Seong-Jin Kim, J. Kim, 2001 .

SOCS3 Attenuates Dexamethasone-Induced M2 Polarization by Down-Regulation of GILZ via ROS- and p38 MAPK-Dependent Pathways

S. Park, Choong-Eun Lee, B. Jung, 2022, Immune network.

Fibroblasts from chronic wounds show altered TGF‐β‐signaling and decreased TGF‐β Type II Receptor expression

S. Park, Seong-Jin Kim, Byung-Chul Kim, 2003 .

Galectin-3 Facilitates Cell Motility in Gastric Cancer by Up-Regulating Protease-Activated Receptor-1(PAR-1) and Matrix Metalloproteinase-1(MMP-1)

S. Park, I. Choi, Y. Bae, 2011, PloS one.

The deubiquitinating enzyme, ubiquitin‐specific peptidase 50, regulates inflammasome activation by targeting the ASC adaptor protein

S. Park, Dongyeob Seo, Su Myung Jung, 2017, FEBS letters.

TRIM24-RIP3 axis perturbation accelerates osteoarthritis pathogenesis

S. Park, You-Sun Kim, Seong-il Eyun, 2020, Annals of the Rheumatic Diseases.

Inactivation of the UASI of STA1 by glucose and STA10 and identification of two loci, SNS1 and MSS1, involved in STA10-dependent repression in Saccharomyces cerevisiae

S. Park, H. Kang, Jin-Hyun Ahn, 1995, Molecular and General Genetics MGG.

mechanism of hepatitis B virus-induced liver fibrosis family signaling through direct interaction with Smad 4 : potential β The hepatitis B virus encoded oncoprotein pX amplifies TGF

S. Park, A. Roberts, M. Caestecker, 2001 .

A20 promotes metastasis of aggressive basal-like breast cancers through multi-monoubiquitylation of Snail1

S. Park, A. Ooshima, Seong-Jin Kim, 2017, Nature Cell Biology.

High A20 expression negatively impacts survival in patients with breast cancer

S. Park, A. Ooshima, Seong-Jin Kim, 2019, PloS one.

Smad6 inhibits non-canonical TGF-β1 signalling by recruiting the deubiquitinase A20 to TRAF6

Jae Young Lee, Young Sun Oh, Ji-Hyung Lee, 2013, Nature Communications.

Galectin-3 germline variant at position 191 enhances nuclear accumulation and activation of β-catenin in gastric cancer

S. Park, I. Choi, Seok-Jun Kim, 2011, Clinical & Experimental Metastasis.

Co-chaperone BAG2 Determines the Pro-oncogenic Role of Cathepsin B in Triple-Negative Breast Cancer Cells.

Yuna Park, S. Park, A. Ooshima, 2017, Cell reports.

Therapeutic effects of mouse bone marrow-derived clonal mesenchymal stem cells in a mouse model of inflammatory bowel disease

S. Park, K. Hahm, K. Lee, 2015, Journal of clinical biochemistry and nutrition.

Apoptosis of mink lung epithelial cells by co-treatment of low-dose staurosporine and transforming growth factor-beta1 depends on the enhanced TGF-beta signaling and requires the decreased phosphorylation of PKB/Akt.

S. Park, Seong-Jin Kim, Kyung-Chul Choi, 2005, Biochemical and biophysical research communications.

Fibroblasts from chronic wounds show altered TGF-beta-signaling and decreased TGF-beta Type II receptor expression.

S. Park, Seong-Jin Kim, V. Falanga, 2003, Journal of cellular physiology.

Transcriptional Regulation of the Transforming Growth Factor β Type II Receptor Gene by Histone Acetyltransferase and Deacetylase Is Mediated by NF-Y in Human Breast Cancer Cells*

E. Sausville, S. Park, Seong-Jin Kim, 2002, The Journal of Biological Chemistry.

Sequence-specific enhancer binding protein is responsible for the differential expression of ERT/ESX/ELF-3/ESE-1/jen gene in human gastric cancer cell lines: Implication for the loss of TGF-β type II receptor expression

S. Park, Seong-Jin Kim, Y. Kim, 2001, Oncogene.

Expression of Caveolin-1 reduces cellular responses to TGF-beta1 through down-regulating the expression of TGF-beta type II receptor gene in NIH3T3 fibroblast cells.

S. Park, E. K. Lee, I. Han, 2007, Biochemical and biophysical research communications.

The deubiquitinating enzyme PSMD14 facilitates tumor growth and chemoresistance through stabilizing the ALK2 receptor in the initiation of BMP6 signaling pathway

S. Park, Jaewon Lee, Dongyeob Seo, 2019, EBioMedicine.

Combination treatment of T1-44, a PRMT5 inhibitor with Vactosertib, an inhibitor of TGF-β signaling, inhibits invasion and prolongs survival in a mouse model of pancreatic tumors

Joon-Oh Park, S. Park, A. Ooshima, 2023, Cell Death & Disease.

Inhibition of TGF-β signalling in combination with nal-IRI plus 5-Fluorouracil/Leucovorin suppresses invasion and prolongs survival in pancreatic tumour mouse models

Joon-Oh Park, S. Park, A. Ooshima, 2020, Scientific Reports.

Fine Tuning and Cross-talking of TGF-β Signal by Inhibitory Smads

S. Park, 2005 .

TRAF6 Mediates IL-1β/LPS-Induced Suppression of TGF-β Signaling through Its Interaction with the Type III TGF-β Receptor

S. Park, Seong-Jin Kim, J. Letterio, 2012, PloS one.

Smad6 negatively regulates interleukin 1-receptor–Toll-like receptor signaling through direct interaction with the adaptor Pellino-1

S. Park, Seong-Jin Kim, Kyung-Chul Choi, 2006, Nature Immunology.

Repeated intratunical injection of adenovirus expressing transforming growth factor-beta1 in a rat induces penile curvature with tunical fibrotic plaque: a useful model for the study of Peyronie's disease.

S. Park, Seong-Jin Kim, J. Han, 2008, International journal of andrology.

Increased expression of 14-3-3ɛ protein in intrinsically aged and photoaged human skin in vivo

J. Chung, S. Park, Mi‐Sun Kim, 2005, Mechanisms of Ageing and Development.

Protein and lipid MALDI profiles classify breast cancers according to the intrinsic subtype

S. Park, H. Kang, H. Kim, 2011, BMC Cancer.

TGF-β and Inhibitory Smads in Inflammation

S. Park, Seong-Jin Kim, 2013 .

Smad7 binds to the adaptors TAB2 and TAB3 to block recruitment of the kinase TAK1 to the adaptor TRAF2

S. Park, Seong-Jin Kim, Allen Li, 2007, Nature Immunology.

749: IN-1130, A Novel Transforming Growth Factor-S Type I Receptor Kinase (ALK5) Inhibitor, Regresses Fibrotic Plaque and Corrects Penile Curvature in a Rat Model of Peyronie's Disease

S. Park, J. Han, J. Suh, 2007 .

Jab1/CSN5, a Component of the COP9 Signalosome, Regulates Transforming Growth Factor β Signaling by Binding to Smad7 and Promoting Its Degradation

S. Park, J. McNally, Seong-Jin Kim, 2004, Molecular and Cellular Biology.

Increased expression of 14-3-3varepsilon protein in intrinsically aged and photoaged human skin in vivo.

J. Chung, S. Park, Mi‐Sun Kim, 2005, Mechanisms of Ageing and Development.

Galectin-3 increases gastric cancer cell motility by up-regulating fascin-1 expression.

S. Park, R. Lotan, I. Choi, 2010, Gastroenterology.

Site-specific monoubiquitination downregulates Rab5 by disrupting effector binding and guanine nucleotide conversion

S. Park, C. Choi, Sangho Lee, 2017, eLife.

Inhibition of TGF-β signalling in combination with nal-IRI plus 5-Fluorouracil/Leucovorin suppresses invasion and prolongs survival in pancreatic tumour mouse models

Joon-Oh Park, S. Park, A. Ooshima, 2020, Scientific Reports.

Decreased expression of glutaredoxin 1 is required for transforming growth factor-beta1-mediated epithelial-mesenchymal transition of EpRas mammary epithelial cells.

S. Park, E. K. Lee, J. Kwon, 2010, Biochemical and biophysical research communications.

A novel SMAD6 variant in a patient with severely calcified bicuspid aortic valve and thoracic aortic aneurysm

S. Park, C. Ki, Jong-Won Kim, 2019, Molecular genetics & genomic medicine.

Anti-inflammatory mechanisms of suppressors of cytokine signaling target ROS via NRF-2/thioredoxin induction and inflammasome activation in macrophages

S. Park, Jae Young Lee, Choong-Eun Lee, 2020, BMB reports.

Peli3 ablation ameliorates acetaminophen-induced liver injury through inhibition of GSK3β phosphorylation and mitochondrial translocation

S. Park, S. Koo, Jaewon Lee, 2023, Experimental & molecular medicine.

Structural mechanism for regulation of Rab7 by site-specific monoubiquitination.

S. Park, C. Choi, Seungsuk Han, 2021, International journal of biological macromolecules.

Decreased expression of glutaredoxin 1 is required for transforming growth factor-beta1-mediated epithelial-mesenchymal transition of EpRas mammary epithelial cells.

S. Park, E. K. Lee, J. Kwon, 2010, Biochemical and biophysical research communications.

Raloxifene, a selective estrogen receptor modulator, inhibits lipopolysaccharide-induced nitric oxide production by inhibiting the phosphatidylinositol 3-kinase/Akt/nuclear factor-kappa B pathway in RAW264.7 macrophage cells.

S. Park, Byung‐Chul Kim, Sin‐Ae Lee, 2008, Molecules and Cells.