B. Krishnamachary

发表

Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1.

G. Semenza, B. Krishnamachary, S. Berg-Dixon, 2003, Cancer research.

Noninvasive detection of lentiviral-mediated choline kinase targeting in a human breast cancer xenograft.

B. Krishnamachary, V. Raman, Z. Bhujwalla, 2009, Cancer research.

Hypoxia-induced human endonuclease G expression suppresses tumor growth in a xenograft model

B. Krishnamachary, F. Vesuna, V. Raman, 2008, Cancer Gene Therapy.

Imaging transplanted stem cells in real time using an MRI dual-contrast method

B. Krishnamachary, D. Artemov, K. Gabrielson, 2015, Scientific Reports.

OS-9 Interacts with Hypoxia-Inducible Factor 1α and Prolyl Hydroxylases to Promote Oxygen-Dependent Degradation of HIF-1α

G. Semenza, B. Krishnamachary, B. Kelly, 2005 .

Expression of DDX3 Is Directly Modulated by Hypoxia Inducible Factor-1 Alpha in Breast Epithelial Cells

B. Krishnamachary, F. Vesuna, V. Raman, 2011, PloS one.

Expression of DDX 3 Is Directly Modulated by Hypoxia Inducible Factor-1 Alpha in Breast Epithelial Cells

B. Krishnamachary, F. Vesuna, V. Raman, 2011 .

Cardiovascular , Pulmonary and Renal Pathology Hypoxia Inducible-Factor 1 Regulates the Metabolic Shift of Pulmonary Hypertensive Endothelial Cells

B. Krishnamachary, S. Erzurum, S. Comhair, 2010 .

Hypoxia inducible-factor1alpha regulates the metabolic shift of pulmonary hypertensive endothelial cells.

B. Krishnamachary, S. Erzurum, S. Comhair, 2010, The American journal of pathology.

Eliminating fibroblast activation protein-α expressing cells by photoimmunotheranostics

B. Krishnamachary, Hisataka Kobayashi, Z. Bhujwalla, 2021, bioRxiv.

Phototheranostics of CD44-positive cell populations in triple negative breast cancer

B. Krishnamachary, Hisataka Kobayashi, Z. Bhujwalla, 2016, Scientific Reports.

Applications of molecular MRI and optical imaging in cancer.

B. Krishnamachary, A. Pathak, Z. Bhujwalla, 2010, Future medicinal chemistry.

Delayed Progression of Lung Metastases Following Delivery of a Prodrug-activating Enzyme.

M. Black, B. Krishnamachary, V. Raman, 2017, Anticancer research.

Extracellular vesicle‐mediated endothelial apoptosis and EV‐associated proteins correlate with COVID‐19 disease severity

B. Krishnamachary, P. Chalise, N. Dhillon, 2021, Journal of extracellular vesicles.

The Potential Role of Extracellular Vesicles in COVID-19 Associated Endothelial injury and Pro-inflammation

B. Krishnamachary, P. Chalise, N. Dhillon, 2020, medRxiv.

Optimized acriflavine‐loaded lipid nanocapsules as a safe and effective delivery system to treat breast cancer

B. Krishnamachary, O. Feron, Z. Bhujwalla, 2018, International journal of pharmaceutics.

Expression of Vascular Endothelial Growth Factor Receptor 1 in Bone Marrow-derived Mesenchymal Cells Is Dependent on Hypoxia-inducible Factor 1*

G. Semenza, B. Krishnamachary, H. Nagasawa, 2006, Journal of Biological Chemistry.

Brain metabolites in cholinergic and glutamatergic pathways are altered by pancreatic cancer cachexia

K. Horton, B. Krishnamachary, A. Maitra, 2020, Journal of cachexia, sarcopenia and muscle.

Metabolic consequences of HIF silencing in a triple negative human breast cancer xenograft

B. Krishnamachary, Z. Bhujwalla, S. Bharti, 2018, Oncotarget.

Breast cancer cell cyclooxygenase-2 expression alters extracellular matrix structure and function and numbers of cancer associated fibroblasts

B. Krishnamachary, M. Solaiyappan, A. Pathak, 2017, Oncotarget.

Stromal Cell – Derived Factor-1 A and CXCR 4 Expression in Hemangioblastoma and Clear Cell-Renal Cell Carcinoma : von Hippel-Lindau Loss-of-Function Induces Expression of a Ligand and Its Receptor

G. Semenza, B. Krishnamachary, J. Melamed, 2005 .

a Ligand and Its Receptor von Hippel-Lindau Loss-of-Function Induces Expression of Hemangioblastoma and Clear Cell-Renal Cell Carcinoma : and CXCR 4 Expression in α Derived Factor-1 − Stromal Cell

G. Semenza, B. Krishnamachary, J. Melamed, 2005 .

HIF and COX-2 expression in triple negative breast cancer cells with hypoxia and 5-fluorouracil

B. Krishnamachary, Z. Bhujwalla, N. Mori, 2020, Current cancer reports.

Molecular and functional imaging insights into the role of hypoxia in cancer aggression

B. Krishnamachary, Z. Bhujwalla, S. Bharti, 2019, Cancer and Metastasis Reviews.

Combining Optical Reporter Proteins with Different Half-lives to Detect Temporal Evolution of Hypoxia and Reoxygenation in Tumors

B. Krishnamachary, Z. Bhujwalla, S. Bharti, 2015, Neoplasia.

Hypoxia-Induced Reporter Genes with Different Half-Lives.

B. Krishnamachary, Z. Bhujwalla, S. Bharti, 2018, Methods in molecular biology.

Hypoxia Patterns in Primary and Metastatic Prostate Cancer Environments1

B. Krishnamachary, Z. Bhujwalla, S. Bharti, 2019, Neoplasia.

Sugen–morphine model of pulmonary arterial hypertension

B. Krishnamachary, Ling Chen, N. Voelkel, 2020, Pulmonary circulation.

The PD-L1 metabolic interactome intersects with choline metabolism and inflammation

B. Krishnamachary, Z. Bhujwalla, Marie-France Penet, 2020, Cancer & metabolism.

PD-L1 siRNA Theranostics With a Dextran Nanoparticle Highlights the Importance of Nanoparticle Delivery for Effective Tumor PD-L1 Downregulation

B. Krishnamachary, Z. Bhujwalla, Marie-France Penet, 2021, Frontiers in Oncology.

Human Cancer Cell Membrane-Coated Biomimetic Nanoparticles Reduce Fibroblast-Mediated Invasion and Metastasis and Induce T-Cells.

B. Krishnamachary, E. Jaffee, Z. Bhujwalla, 2019, ACS applied materials & interfaces.

TGF-Î²1 in extracellular vesicles from HIV-infected plasma and macrophages linked to cardiopulmonary dysfunction

B. Krishnamachary, S. Agarwal, A. Morris, 2020, medRxiv.

Extracellular Vesicle TGF- b 1 Is Linked to Cardiopulmonary Dysfunction in Human Immunodeficiency Virus

B. Krishnamachary, S. Agarwal, P. Hsue, 2021 .

OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.

G. Semenza, B. Krishnamachary, B. Kelly, 2005, Molecular cell.

Degradable Dextran Nanopolymer as a Carrier for Choline Kinase (ChoK) siRNA Cancer Therapy

B. Krishnamachary, Z. Bhujwalla, Zhihang Chen, 2016, Nanomaterials.

VEGF Overexpression Significantly Increases Nanoparticle-Mediated siRNA Delivery and Target-Gene Downregulation

B. Krishnamachary, Z. Bhujwalla, N. Mori, 2022, Pharmaceutics.

Evaluating near‐infrared photoimmunotherapy for targeting fibroblast activation protein‐α expressing cells in vitro and in vivo

B. Krishnamachary, Hisataka Kobayashi, Z. Bhujwalla, 2022, Cancer science.

HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity.

G. Semenza, B. Krishnamachary, K. Zeller, 2007, Cancer cell.

Bhanupaka: A Green Process in the Preparation of an Indian Ayurvedic Medicine, Lauha Bhasma

B. Krishnamachary, U. Krishnan, S. Sethuraman, 2013 .

Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone

B. Krishnamachary, S. Anant, D. Subramaniam, 2019, Oncotarget.

Effect of Pantethine on Ovarian Tumor Progression and Choline Metabolism

B. Krishnamachary, Z. Bhujwalla, F. Podo, 2016, Front. Oncol..

Structure and Function of a Prostate Cancer Dissemination–Permissive Extracellular Matrix

B. Krishnamachary, M. Solaiyappan, A. Pathak, 2016, Clinical Cancer Research.

Molecular and Functional Imaging and Theranostics of the Tumor Microenvironment

B. Krishnamachary, Z. Bhujwalla, S. Bharti, 2021, Molecular Imaging.

Molecular and functional imaging insights into the role of hypoxia in cancer aggression

B. Krishnamachary, Z. Bhujwalla, S. Bharti, 2019, Cancer and Metastasis Reviews.

Molecular imaging of the tumor microenvironment for precision medicine and theranostics.

Zaver M Bhujwalla, B. Krishnamachary, Z. Bhujwalla, 2014, Advances in cancer research.

Breast cancer cell adhesome and degradome interact to drive metastasis

B. Krishnamachary, Z. Bhujwalla, Lu Jiang, 2015, npj Breast Cancer.

Molecular and functional imaging of invasion and metastasis: windows into the metastatic cascade.

B. Krishnamachary, Z. Bhujwalla, Marie-France Penet, 2011, Cancer biomarkers : section A of Disease markers.

Cucurbitacin B and I inhibits colon cancer growth by targeting the Notch signaling pathway

B. Krishnamachary, G. Kaushik, R. Jensen, 2020, Scientific Reports.

Targeting choline phospholipid metabolism: GDPD5 and GDPD6 silencing decrease breast cancer cell proliferation, migration, and invasion

B. Krishnamachary, T. Bathen, Z. Bhujwalla, 2016, NMR in biomedicine.

Hypoxia Regulates CD44 and Its Variant Isoforms through HIF-1α in Triple Negative Breast Cancer

G. Semenza, B. Krishnamachary, M. Solaiyappan, 2012, PloS one.

HIF-1-dependent Expression of Angiopoietin-like 4 and L1CAM Mediates Vascular Metastasis of Hypoxic Breast Cancer Cells to the Lungs

G. Semenza, B. Krishnamachary, S. Sukumar, 2011, Oncogene.

Theranostic small interfering RNA nanoparticles in cancer precision nanomedicine.

B. Krishnamachary, Z. Bhujwalla, Marie-France Penet, 2019, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.

Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B.

G. Semenza, B. Krishnamachary, D. Zagzag, 2006, Cancer research.

Hypoxia Inducible Factors Modify Collagen I Fibers in MDA-MB-231 Triple Negative Breast Cancer Xenografts12

B. Krishnamachary, Z. Bhujwalla, F. Wildes, 2017, Neoplasia.

Global metabolic profile identifies choline kinase alpha as a key regulator of glutathione-dependent antioxidant cell defense in ovarian carcinoma

B. Krishnamachary, Z. Bhujwalla, S. Canevari, 2015, Oncotarget.

Hypoxia theranostics of a human prostate cancer xenograft and the resulting effects on the tumor microenvironment

M. Black, B. Krishnamachary, Z. Bhujwalla, 2020, Neoplasia.

Spontaneous transformation of cultured mouse bone marrow-derived stromal cells.

G. Semenza, B. Krishnamachary, D. Huso, 2006, Cancer research.

Persistent circulation of soluble and extracellular vesicle‐linked Spike protein in individuals with postacute sequelae of COVID‐19

B. Krishnamachary, P. Chalise, A. Mahajan, 2023, Journal of medical virology.

Choline Metabolism Alteration: A Focus on Ovarian Cancer

B. Krishnamachary, Z. Bhujwalla, S. Canevari, 2016, Front. Oncol..

Stromal Cell–Derived Factor-1α and CXCR4 Expression in Hemangioblastoma and Clear Cell-Renal Cell Carcinoma: von Hippel-Lindau Loss-of-Function Induces Expression of a Ligand and Its Receptor

G. Semenza, B. Krishnamachary, J. Melamed, 2005 .

Metastatic breast cancer cells in lymph nodes increase nodal collagen density

B. Krishnamachary, Z. Bhujwalla, Lu Jiang, 2015, Scientific Reports.

Metabolic signatures imaged in cancer-induced cachexia.

B. Krishnamachary, M. Pomper, Z. Bhujwalla, 2011, Cancer research.

Acid-degradable Dextran as an Image Guided siRNA Carrier for COX-2 Downregulation

B. Krishnamachary, Z. Bhujwalla, Marie-France Penet, 2018, Theranostics.

COX-2 in cancer: Gordian knot or Achilles heel?

B. Krishnamachary, Z. Bhujwalla, Marie-France Penet, 2013, Front. Pharmacol..

MRI and MRS of intact perfused cancer cell metabolism, invasion, and stromal cell interactions

B. Krishnamachary, Z. Bhujwalla, S. Bharti, 2019, NMR in biomedicine.

Collagen fibers mediate MRI-detected water diffusion and anisotropy in breast cancers

Meiyappan Solaiyappan, Michael A. Jacobs, Alireza Akhbardeh, 2016, Neoplasia.

Phospholipase D1 and choline kinase-α are interactive targets in breast cancer

B. Krishnamachary, I. Gribbestad, Z. Bhujwalla, 2014, Cancer biology & therapy.

Analysis of hypoxia-inducible factor 1alpha expression and its effects on invasion and metastasis.

G. Semenza, B. Krishnamachary, 2007, Methods in enzymology.

Scientific validation of the different purification steps involved in the preparation of an Indian Ayurvedic medicine, Lauha bhasma.

B. Krishnamachary, U. Krishnan, S. Sethuraman, 2012, Journal of ethnopharmacology.

ELUCIDATION OF A CORE-SHELL MODEL FOR LAUHA BHASMA THROUGH PHYSICO- CHEMICAL CHARACTERIZATION

Krishnan, B. Krishnamachary, U. Maheswari, 2012 .

Molecular causes of elevated phosphoethanolamine in breast and pancreatic cancer cells

B. Krishnamachary, Z. Bhujwalla, F. Wildes, 2018, NMR in biomedicine.

Metabolic Imaging of Pancreatic Ductal Adenocarcinoma Detects Altered Choline Metabolism

B. Krishnamachary, A. Maitra, Z. Bhujwalla, 2014, Clinical Cancer Research.

Reprogramming of VEGF-mediated extracellular matrix changes through autocrine signaling

B. Krishnamachary, Z. Bhujwalla, F. Wildes, 2023, Cancer biology & therapy.

Functional roles of FAP-α in metabolism, migration and invasion of human cancer cells

B. Krishnamachary, F. Vesuna, Z. Bhujwalla, 2023, Frontiers in Oncology.

Characterization of choline kinase in human endothelial cells

B. Krishnamachary, Z. Bhujwalla, N. Mori, 2013, NMR in biomedicine.

B. Krishnamachary, A. Faden, Junfang Wu, 2023, Research square.

Ascites Volumes and the Ovarian Cancer Microenvironment

B. Krishnamachary, Z. Bhujwalla, T. Wu, 2018, Front. Oncol..

Integrated Systems and Technologies Metabolic Signatures Imaged in Cancer-Induced Cachexia

B. Krishnamachary, M. Pomper, Z. Bhujwalla, 2011 .

HIF isoforms have divergent effects on invasion, metastasis, metabolism and formation of lipid droplets

B. Krishnamachary, Z. Bhujwalla, F. Wildes, 2015, Oncotarget.

PSMA-specific theranostic nanoplex for combination of TRAIL gene and 5-FC prodrug therapy of prostate cancer.

B. Krishnamachary, M. Pomper, Z. Bhujwalla, 2016, Biomaterials.

PD-L1 near Infrared Photoimmunotherapy of Ovarian Cancer Model

B. Krishnamachary, Hisataka Kobayashi, Z. Bhujwalla, 2022, Cancers.

PET/MRI and Bioluminescent Imaging Identify Hypoxia as a Cause of Programmed Cell Death Ligand 1 Image Heterogeneity.

B. Krishnamachary, M. Solaiyappan, M. McMahon, 2023, Radiology. Imaging cancer.

Glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) expression correlates with malignant choline phospholipid metabolite profiles in human breast cancer

P. Lønning, B. Krishnamachary, I. Gribbestad, 2012, NMR in biomedicine.

Stromal cell-derived factor-1alpha and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: von Hippel-Lindau loss-of-function induces expression of a ligand and its receptor.

G. Semenza, B. Krishnamachary, J. Melamed, 2005, Cancer research.

Silencing of the glycerophosphocholine phosphodiesterase GDPD5 alters the phospholipid metabolite profile in a breast cancer model in vivo as monitored by 31P MRS

B. Krishnamachary, D. Klomp, Z. Bhujwalla, 2014, NMR in biomedicine.

Cucurbitacin B and I inhibits colon cancer growth by targeting the Notch signaling pathway

B. Krishnamachary, G. Kaushik, R. Jensen, 2020, Scientific Reports.

Abstract 3164: Cancer cell adhesion and degradome interact to metastasize

B. Krishnamachary, Z. Bhujwalla, Lu Jiang, 2014 .

Metabolic Imaging to Assess Treatment Response to Cytotoxic and Cytostatic Agents

B. Krishnamachary, Z. Bhujwalla, S. Eckhardt, 2016, Front. Oncol..

Prostate fibroblasts and prostate cancer associated fibroblasts exhibit different metabolic, matrix degradation and PD-L1 expression responses to hypoxia

Raj Kumar Sharma, B. Krishnamachary, Z. Bhujwalla, 2024, Frontiers in Molecular Biosciences.

Acidosis-mediated increase in IFN-γ-induced PD-L1 expression on cancer cells as an immune escape mechanism in solid tumors

B. Krishnamachary, Z. Bhujwalla, D. Bomze, 2023, Molecular cancer.