J. Polli

发表

Quality-by-Design III: Application of Near-Infrared Spectroscopy to Monitor Roller Compaction In-process and Product Quality Attributes of Immediate Release Tablets

R. Kona, R. Fahmy, Gregg Claycamp, 2015, AAPS PharmSciTech.

Recent advances in ligand-based drug design: relevance and utility of the conformationally sampled pharmacophore approach.

Alexander D. MacKerell, J. Polli, A. Coop, 2011, Current computer-aided drug design.

Rapid Identification of P-glycoprotein Substrates and Inhibitors

Praveen M. Bahadduri, J. Polli, S. Ekins, 2006, Drug Metabolism and Disposition.

Targeting drug transporters - combining in silico and in vitro approaches to predict in vivo.

Sean Ekins, Peter W Swaan, James E Polli, 2010, Methods in molecular biology.

Biopharmaceutics Classification System: The Scientific Basis for Biowaiver Extensions

Vinod P. Shah, Lawrence X. Yu, Ajaz S. Hussain, 2002, Pharmaceutical Research.

Metformin Disrupts Bile Acid Efflux by Repressing Bile Salt Export Pump Expression

J. Polli, S. Heyward, Shiew-Mei Huang, 2020, Pharmaceutical Research.

Characterization of Grades of HPMCAS Spray Dried Dispersions of Itraconazole Based on Supersaturation Kinetics and Molecular Interactions Impacting Formulation Performance

J. Polli, Asmita Adhikari, 2020, Pharmaceutical Research.

A substrate pharmacophore for the human organic cation/carnitine transporter identifies compounds associated with rhabdomyolysis.

Sean Ekins, James E Polli, Lei Diao, 2012, Molecular pharmaceutics.

Lipid composition effect on permeability across PAMPA.

J. Kao, J. Polli, Paul R. Seo, 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Prediction of dissolution-absorption relationships from a dissolution/Caco-2 system.

J. Polli, M. Ginski, 1999, International journal of pharmaceutics.

Multidrug and toxin extrusion proteins mediate cellular transport of cadmium

J. Polli, Hong Yang, Yan Shu, 2017, Toxicology and applied pharmacology.

A 19F magnetic resonance imaging-based diagnostic test for bile acid diarrhea

J. Polli, J. Raufman, Su Xu, 2018, Magnetic Resonance Materials in Physics, Biology and Medicine.

Diminished gallbladder filling, increased fecal bile acids, and promotion of colon epithelial cell proliferation and neoplasia in fibroblast growth factor 15-deficient mice

J. Polli, M. Zhan, C. Drachenberg, 2018, Oncotarget.

Attenuated Accumulation of Novel Fluorine (19F)-Labeled Bile Acid Analogues in Gallbladders of Fibroblast Growth Factor-15 (FGF15)-Deficient Mice.

J. Polli, J. Raufman, Su Xu, 2018, Molecular pharmaceutics.

In Vivo Performance of a Novel Fluorinated Magnetic Resonance Imaging Agent for Functional Analysis of Bile Acid Transport

J. Polli, P. Dawson, J. Raufman, 2014, Molecular pharmaceutics.

Design and evaluation of a novel trifluorinated imaging agent for assessment of bile acid transport using fluorine magnetic resonance imaging.

J. Polli, P. Dawson, J. Raufman, 2014, Journal of pharmaceutical sciences.

Equivalence and regulatory approaches of nonbiological complex drug products across the United States, the European Union, and Turkey

J. Polli, S. Michel, Z. G. Oner, 2017, Annals of the New York Academy of Sciences.

Slc10a2-null mice uncover colon cancer-promoting actions of endogenous fecal bile acids.

J. Polli, M. Zhan, P. Dawson, 2015, Carcinogenesis.

Ondansetron can enhance cisplatin-induced nephrotoxicity via inhibition of multiple toxin and extrusion proteins (MATEs).

J. Polli, Shiew-Mei Huang, Wei Zhang, 2013, Toxicology and applied pharmacology.

Evaluation of Excipient Risk in BCS Class I and III Biowaivers

J. Polli, Melissa Metry, 2022, The AAPS journal.

Identification of inhibitor concentrations to efficiently screen and measure inhibition Ki values against solute carrier transporters.

J. Polli, Xiaowan Zheng, 2010, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

A substrate pharmacophore for the human sodium taurocholate co-transporting polypeptide.

J. Polli, S. Ekins, Zhongqi Dong, 2015, International journal of pharmaceutics.

Chemical substituent effect on pyridine permeability and mechanistic insight from computational molecular descriptors.

Alexander D. MacKerell, J. Polli, D. Yin, 2006, Molecular pharmaceutics.

Transport of poly amidoamine dendrimers across Madin-Darby canine kidney cells.

J. Polli, H. Ghandehari, M. El-Sayed, 2001, International journal of pharmaceutics.

Considerations for a Pediatric Biopharmaceutics Classification System (BCS): Application to Five Drugs

M. Khan, J. Polli, W. Rodriguez, 2014, AAPS PharmSciTech.

Quantification of Acyclovir in Human Plasma by Ultra-High-Performance Liquid Chromatography - Heated Electrospray Ionization - Tandem Mass Spectrometry for Bioequivalence Evaluation

Lawrence X. Yu, J. Polli, M. Kane, 2012 .

Quality of antiretroviral and opportunistic infection medications dispensed from developing countries and Internet pharmacies

J. Polli, S. Hoag, N. Pandit, 2015, Journal of clinical pharmacy and therapeutics.

The Role of Bile Salt Export Pump Gene Repression in Drug-Induced Cholestatic Liver Toxicity

J. Polli, Shiew-Mei Huang, Lei Zhang, 2014, Drug Metabolism and Disposition.

Short Communication: The role of bile salt export pump (BSEP) gene repression in drug-induced cholestatic liver toxicity

Hongbing, J. Polli, Shiew-Mei Huang, 2013 .

Theme: Revisiting Ivivc (in Vitro-in Vivo Correlation) Exploring Canine-human Differences in Product Performance. Part Ii: Use of Modeling and Simulation to Explore the Impact of Formulation on Ciprofloxacin in Vivo Absorption and Dissolution in Dogs

R. Kona, R. Fahmy, J. Polli, 2022 .

Apical sodium dependent bile acid transporter (ASBT, SLC10A2): a potential prodrug target.

J. Polli, Anand Balakrishnan, 2006, Molecular pharmaceutics.

Biowaiver Monograph for Immediate-Release Solid Oral Dosage Forms: Sitagliptin phosphate monohydrate.

Naseem A. Charoo, J. Polli, A. Parr, 2021, Journal of pharmaceutical sciences.

Indinavir Alters the Pharmacokinetics of Lamivudine Partially via Inhibition of Multidrug and Toxin Extrusion Protein 1 (MATE1)

Jin Huang, Hong Yang, Dong Guo, 2018, Pharmaceutical Research.

Irinotecan Alters the Disposition of Morphine Via Inhibition of Organic Cation Transporter 1 (OCT1) and 2 (OCT2)

J. Polli, Wei Zhang, Qing Li, 2018, Pharmaceutical Research.

Effect of Ondansetron on Metformin Pharmacokinetics and Response in Healthy Subjects

J. Polli, Hong Yang, Qing Li, 2016, Drug Metabolism and Disposition.

Biowaiver Monograph for Immediate-Release Solid Oral Dosage Forms: Moxifloxacin hydrochloride.

Naseem A. Charoo, J. Polli, A. Parr, 2020, Journal of pharmaceutical sciences.

Mathematical model and dimensional analysis of glycocholate binding to cholestyramine resin: implications for in vivo resin performance.

J. Polli, G. Amidon, 1995, Journal of pharmaceutical sciences.

Biowaiver monograph for immediate-release solid oral dosage forms: fluconazole.

Naseem A. Charoo, J. Polli, V. Shah, 2014, Journal of pharmaceutical sciences.

Dependence of in vitro-in vivo correlation analysis acceptability on model selections.

J. Polli, 1999, Pharmaceutical development and technology.

In vitro-in vivo relationships of several "immediate" release tablets containing a low permeability drug.

J. Polli, 1997, Advances in experimental medicine and biology.

Generic lamotrigine versus brand‐name Lamictal bioequivalence in patients with epilepsy: A field test of the FDA bioequivalence standard

Jace W. Jones, J. Polli, R. Temple, 2015, Epilepsia.

Inhibition Requirements of the Human Apical Sodium-Dependent Bile Acid Transporter (hASBT) Using Aminopiperidine Conjugates of glutamyl-Bile Acids

Alexander D. MacKerell, J. Polli, C. Acharya, 2009, Pharmaceutical Research.

J. Polli, K. Morris, Harsh S. Shah, 2020, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Authorized Generic Drugs: an Overview

J. Polli, Z. Gulsen Oner, 2018, AAPS PharmSciTech.

Workshop Report: Implementation of Biowaivers based on the Biopharmaceutics Classification System

J. Polli, V. Shah, P. Langguth, 2017 .

Meeting report: International workshop on implementation of biowaivers based on the biopharmaceutics classification system (BCS)

J. Polli, V. Shah, J. Dressman, 2015 .

Structural requirements of the ASBT by 3D-QSAR analysis using aminopyridine conjugates of chenodeoxycholic acid.

J. Polli, P. Swaan, Yongmei Pan, 2010, Bioconjugate chemistry.

Method to Screen Substrates of Apical Sodium-Dependent Bile Acid Transporter

J. Polli, R. Rais, S. Wring, 2008, The AAPS Journal.

Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Levetiracetam.

J. Polli, V. Shah, J. Dressman, 2015, Journal of pharmaceutical sciences.

Synthesis and in vitro evaluation of potential sustained release prodrugs via targeting ASBT.

J. Polli, Xiaowan Zheng, 2010, International journal of pharmaceutics.

Identification of novel nonsteroidal compounds as substrates or inhibitors of hASBT.

Alexander D. MacKerell, J. Polli, Vidula Kolhatkar, 2012, Journal of pharmaceutical sciences.

Transmembrane Helix 1 Contributes to Substrate Translocation and Protein Stability of Bile Acid Transporter SLC10A2*

J. Polli, P. Swaan, T. C. da Silva, 2011, The Journal of Biological Chemistry.

Synthesis and in vitro evaluation of gabapentin prodrugs that target the human apical sodium-dependent bile acid transporter (hASBT).

J. Polli, S. Fletcher, R. Rais, 2011, Journal of pharmaceutical sciences.

Differential effects of metformin‐mediated BSEP repression on pravastatin and bile acid pharmacokinetics in humans: A randomized controlled trial

J. Polli, Hongbing Wang, J. Fink, 2022, Clinical and translational science.

Impact of Impurity on Kinetic Estimates from Transport and Inhibition Studies

J. Polli, P. González, 2008, Journal of Pharmacology and Experimental Therapeutics.

Reply to "On the Effect of Common Excipients on the Oral Absorption of Class 3 Drugs".

J. Polli, S. Hoag, M. Kane, 2016, Journal of pharmaceutical sciences.

Release of levetiracetam from extended-release tablets that appear intact in patient stool

J. Polli, T. Ting, Wenlei Jiang, 2016, Seizure.

Quantitative Structure Activity Relationship for Inhibition of Human Organic Cation/Carnitine Transporter (OCTN2)

J. Polli, S. Ekins, Lei Diao, 2011 .

Summary Workshop Report: Facilitating Oral Product Development and Reducing Regulatory Burden Through Novel Approaches to Assess Bioavailability/Bioequivalence

Francis X. Muller, Amitava Mitra, Jack A. Cook, 2012, AAPS Journal.

In Vitro Studies are Sometimes Better than Conventional Human Pharmacokinetic In Vivo Studies in Assessing Bioequivalence of Immediate-Release Solid Oral Dosage Forms

J. Polli, 2008, The AAPS Journal.

Prediction of In Vitro Drug Dissolution into Fed-state Biorelevant Media: Contributions of Solubility Enhancement and Relatively Low Colloid Diffusivity.

J. Polli, Raqeeb G. Jamil, 2022, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Quantification of Lamotrigine in Patient Plasma Using a Fast Liquid Chromatography–Tandem Mass Spectrometry Method With Backflush Technology

Jace W. Jones, J. Polli, M. Kane, 2015, Therapeutic drug monitoring.

Effects of nonionic surfactants on membrane transporters in Caco-2 cell monolayers.

James E Polli, J. Kao, J. Polli, 2002, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Biowaiver monographs for immediate-release solid oral dosage forms: Zidovudine (azidothymidine).

K. C. Soares, J. Polli, V. Shah, 2013, Journal of pharmaceutical sciences.

Comparison of a single pharmaceutical surfactant versus intestinal biorelevant media for etravirine dissolution: role and impact of micelle diffusivity.

J. Polli, Ayşe Nur OKTAY, 2022, International journal of pharmaceutics.

Computational Models to Assign Biopharmaceutics Drug Disposition Classification from Molecular Structure

Sean Ekins, James E. Polli, Peter W. Swaan, 2007, Pharmaceutical Research.

Prediction of Food Effect On In Vitro Drug Dissolution into Biorelevant Media: Contributions of Solubility Enhancement and Relatively Low Colloid Diffusivity.

J. Polli, Raqeeb G. Jamil, 2022, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Methods to compare dissolution profiles and a rationale for wide dissolution specifications for metoprolol tartrate tablets.

J. Polli, V. Shah, L. Augsburger, 1997, Journal of pharmaceutical sciences.

Understanding Pharmaceutical Quality by Design

G. K. Raju, Lawrence X. Yu, Mansoor A. Khan, 2014, The AAPS Journal.

Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Ribavirin

J. Polli, V. Shah, J. Dressman, 2016, Journal of Pharmaceutical Sciences.

Novel Metrics to Compare Dissolution Profiles

J. Polli, V. Shah, Paul R. Seo, 2002, Pharmaceutical development and technology.

Methods to Compare Dissolution Profiles*

J. Polli, V. Shah, G. S. Rekhi, 1996 .

Effect of common excipients on Caco-2 transport of low-permeability drugs.

Lawrence X. Yu, J. Polli, A. Hussain, 2001, Journal of pharmaceutical sciences.

Biowaiver monographs for immediate release solid oral dosage forms: efavirenz.

J. Polli, V. Shah, J. Dressman, 2013, Journal of pharmaceutical sciences.

Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Cephalexin Monohydrate.

J. Polli, A. Parr, V. Shah, 2020, Journal of pharmaceutical sciences.

Prediction of In Vitro Drug Dissolution into Fasted-state Biorelevant Media: Contributions of Solubility Enhancement and Relatively Low Colloid Diffusivity.

J. Polli, Raqeeb G. Jamil, 2022, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Surfactant-mediated dissolution: contributions of solubility enhancement and relatively low micelle diffusivity.

Anand Balakrishnan, James E Polli, Gordon L Amidon, 2004, Journal of pharmaceutical sciences.

Structure-activity relationship for FDA approved drugs as inhibitors of the human sodium taurocholate cotransporting polypeptide (NTCP).

Sean Ekins, Zhongqi Dong, James E Polli, 2013, Molecular pharmaceutics.

Structure Activity Relationship for FDA Approved Drugs as Inhibitors of the Human Sodium Taurocholate Co-transporting Polypeptide (NTCP)

J. Polli, S. Ekins, Zhongqi Dong, 2012 .

Biowaiver monographs for immediate release solid oral dosage forms: diclofenac sodium and diclofenac potassium.

D. Barends, J. Polli, G. Amidon, 2009, Journal of pharmaceutical sciences.

Biowaiver Monographs for Immediate-Release Solid Oral Dosage Forms: Folic Acid.

J. Polli, A. Parr, V. Shah, 2017, Journal of pharmaceutical sciences.

Biowaiver monographs for immediate release solid oral dosage forms: quinidine sulfate.

D. Barends, J. Polli, H. Junginger, 2009, Journal of pharmaceutical sciences.

Synthesis and in vitro evaluation of bile acid prodrugs of floxuridine to target the liver.

J. Polli, Diana Vivian, 2014, International journal of pharmaceutics.

Selective Inhibition on Organic Cation Transporters by Carvedilol Protects Mice from Cisplatin-Induced Nephrotoxicity

J. Polli, Hong Yang, Qing Li, 2018, Pharmaceutical Research.

Bias in Estimation of Transporter Kinetic Parameters from Overexpression Systems: Interplay of Transporter Expression Level and Substrate Affinity

J. Polli, P. Swaan, M. Bermejo, 2007, Journal of Pharmacology and Experimental Therapeutics.

Gordon L. Amidon: Very Sustained Drug Absorption.

Lawrence X. Yu, J. Polli, B. Vig, 2015, Journal of pharmaceutical sciences.

Summary Workshop Report: Bioequivalence, Biopharmaceutics Classification System, and Beyond

Jack A. Cook, Vinod P. Shah, Lawrence X. Yu, 2008, The AAPS Journal.

Evaluation of Excipient Risk in BCS Class I and III Biowaivers

J. Polli, Melissa Metry, 2022, The AAPS Journal.

Fast liquid chromatography-tandem mass spectrometry method for simultaneous determination of eight antiepileptic drugs and an active metabolite in human plasma using polarity switching and timed selected reaction monitoring.

Jace W. Jones, J. Polli, M. Kane, 2019, Journal of pharmaceutical and biomedical analysis.

The solute carrier family 10 (SLC10): beyond bile acid transport.

J. Polli, P. Swaan, Tatiana Claro da Silva, 2013, Molecular aspects of medicine.

Comparison of Drug Permeabilities and BCS Classification: Three Lipid-Component PAMPA System Method versus Caco-2 Monolayers

J. Polli, Paul R. Seo, Z. Teksin, 2010, The AAPS Journal.

Biowaiver monographs for immediate release solid oral dosage forms: mefloquine hydrochloride.

D. Barends, J. Polli, H. Junginger, 2011, Journal of pharmaceutical sciences.

Phrygian Cap Appearance of a Mouse Gallbladder on Magnetic Resonance Imaging.

R. Gullapalli, J. Polli, J. Raufman, 2013, Journal of veterinary science & medical diagnosis.

In situ kinetic modelling of intestinal efflux in rats: functional characterization of segmental differences and correlation with in vitro results

J. Polli, M. Bermejo, I. González-Álvarez, 2007, Biopharmaceutics & drug disposition.

Snapshots of Iron Speciation: Tracking the Fate of Iron Nanoparticle Drugs via a Liquid Chromatography-Inductively Coupled Plasma-Mass Spectrometric Approach.

J. Polli, J. Fink, M. Kane, 2019, Molecular pharmaceutics.

Weight uniformity of split tablets required by a Veterans Affairs policy.

J. Polli, Sharon Kim, Brian R Martin, 2003, Journal of managed care pharmacy : JMCP.

Statistics on BCS Classification of Generic Drug Products Approved Between 2000 and 2011 in the USA

Lawrence X. Yu, J. Polli, M. Mehta, 2012, The AAPS Journal.

Midazolam Exhibits Characteristics of a Highly Permeable P-Glycoprotein Substrate

J. Polli, J. Polli, J. Rautio, 2003, Pharmaceutical Research.

Putative Irreversible Inhibitors of the Human Sodium-Dependent Bile Acid Transporter (hASBT; SLC10A2) Support the Role of Transmembrane Domain 7 in Substrate Binding/Translocation

Alexander D. MacKerell, J. Polli, P. Swaan, 2012, Pharmaceutical Research.

Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Proguanil Hydrochloride.

J. Polli, A. Parr, V. Shah, 2018, Journal of pharmaceutical sciences.

Biowaiver monographs for immediate-release solid oral dosage forms: primaquine phosphate.

D. Barends, J. Polli, V. Shah, 2012, Journal of pharmaceutical sciences.

Considerations for a Pediatric Biopharmaceutics Classification System (BCS): Application to Five Drugs

M. Khan, J. Polli, W. Rodriguez, 2014, AAPS PharmSciTech.

Utility of Films to Anticipate Effect of Drug Load and Polymer on Dissolution Performance from Tablets of Amorphous Itraconazole Spray-Dried Dispersions

R. G. Hollenbeck, J. Polli, S. Hoag, 2019, AAPS PharmSciTech.

Biowaiver monographs for immediate-release solid oral dosage forms: ketoprofen.

D. Barends, J. Polli, V. Shah, 2012, Journal of pharmaceutical sciences.

Lack of medication dose uniformity in commonly split tablets.

James E Polli, J. Polli, Roger L Williams, 2002, Journal of the American Pharmaceutical Association.

Optimizing Clinical Drug Product Performance: Applying Biopharmaceutics Risk Assessment Roadmap (BioRAM) and the BioRAM Scoring Grid.

Talia Flanagan, Anette Müllertz, Filippos Kesisoglou, 2016, Journal of pharmaceutical sciences.

The effects of spray drying, HPMCAS grade, and compression speed on the compaction properties of itraconazole-HPMCAS spray dried dispersions.

J. Polli, S. Hoag, A. Zidan, 2020, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The biopharmaceutics risk assessment roadmap for optimizing clinical drug product performance.

Anette Müllertz, Arzu Selen, Hans Lennernäs, 2014, Journal of pharmaceutical sciences.

The Use of BDDCS in Classifying the Permeability of Marketed Drugs

Vinod P. Shah, Lawrence X. Yu, James E. Polli, 2008, Pharmaceutical Research.

Use of Modeling and Simulation Tools for Understanding the Impact of Formulation on the Absorption of a Low Solubility Compound: Ciprofloxacin

R. Kona, R. Fahmy, J. Polli, 2016, The AAPS Journal.

Quality-by-Design III: Application of Near-Infrared Spectroscopy to Monitor Roller Compaction In-process and Product Quality Attributes of Immediate Release Tablets

R. Kona, R. Fahmy, Gregg Claycamp, 2015, AAPS PharmSciTech.

Development of a more rapid, reduced serum culture system for Caco-2 monolayers and application to the biopharmaceutics classification system.

J. Polli, J. Hayashi, K. Lentz, 2000, International journal of pharmaceutics.

Prediction of positive food effect: Bioavailability enhancement of BCS class II drugs.

J. Polli, Siddarth Raman, 2016, International journal of pharmaceutics.

Biowaiver monograph for immediate-release solid oral dosage forms: bisoprolol fumarate.

Naseem A. Charoo, J. Polli, V. Shah, 2014, Journal of pharmaceutical sciences.

Pharmacopeial Standards for the Subdivision Characteristics of Scored Tablets

J. Polli, C. Berg, G. Green, 2009 .

3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration

Benjamin S. Freedman, J. Polli, S. Heyward, 2021, Clinical and translational science.

Prescriber Perspectives on Biosimilar Adoption and Potential Role of Clinical Pharmacology: A Workshop Summary

Yow-Ming C Wang, J. Polli, G. Lyman, 2022, Clinical pharmacology and therapeutics.

Targeted drug delivery systems 6: Intracellular bioreductive activation, uptake and transport of an anticancer drug delivery system across intestinal Caco-2 cell monolayers.

J. Polli, L. Gharat, N. Weerapreeyakul, 2001, International journal of pharmaceutics.

Structural requirements of bile acid transporters: C-3 and C-7 modifications of steroidal hydroxyl groups.

J. Polli, Vidula Kolhatkar, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Structural determinants for transport across the intestinal bile acid transporter using C-24 bile acid conjugates.

Alexander D. MacKerell, Chayan Acharya, Alexander D Mackerell, 2010, Molecular pharmaceutics.

Reliability of Inhibition Models to Correctly Identify Type of Inhibition

J. Polli, Vidula Kolhatkar, 2010, Pharmaceutical Research.

Molecular switch controlling the binding of anionic bile acid conjugates to human apical sodium-dependent bile acid transporter.

Alexander D. MacKerell, Chayan Acharya, Alexander D Mackerell, 2010, Journal of medicinal chemistry.

Interaction of Native Bile Acids with Human Apical Sodium-Dependent Bile Acid Transporter (hASBT): Influence of Steroidal Hydroxylation Pattern and C-24 Conjugation

J. Polli, Anand Balakrishnan, S. Wring, 2006, Pharmaceutical Research.

Influence of charge and steric bulk in the C-24 region on the interaction of bile acids with human apical sodium-dependent bile acid transporter.

J. Polli, A. Coop, Anand Balakrishnan, 2006, Molecular pharmaceutics.

Development of Stably Transfected Monolayer Overexpressing the Human Apical Sodium-Dependent Bile Acid Transporter (hASBT)

J. Polli, Anand Balakrishnan, D. Sussman, 2005, Pharmaceutical Research.

In vitro characterization of sodium glycocholate binding to cholestyramine resin.

J. Polli, G. Amidon, 1995, Journal of pharmaceutical sciences.

Biowaiver Monographs for Immediate-Release Solid Oral Dosage Forms: Enalapril.

J. Polli, R. Löbenberg, I. Kanfer, 2017, Journal of pharmaceutical sciences.

Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Metformin Hydrochloride.

J. Polli, A. Parr, V. Shah, 2021, Journal of pharmaceutical sciences.

ICH M9 Guideline in development on Biopharmaceutics Classification System-based biowaivers: An Industrial Perspective from the IQ Consortium.

Yunhui Wu, David Lindley, Manish Gupta, 2019, Molecular pharmaceutics.

Synthesis and in vitro characterization of drug conjugates of l-carnitine as potential prodrugs that target human Octn2.

J. Polli, Lei Diao, 2011, Journal of pharmaceutical sciences.

Authorized Generic Drugs: an Overview

J. Polli, Z. Gulsen Oner, 2018, AAPS PharmSciTech.

Ischemia/Reperfusion-inducible protein modulates the function of organic cation transporter 1 and multidrug and toxin extrusion 1.

J. Polli, Qing Li, Yan Shu, 2013, Molecular pharmaceutics.

Why we should be vigilant: drug cytotoxicity observed with in vitro transporter inhibition studies.

Sean Ekins, James E Polli, Lei Diao, 2010, Biochemical pharmacology.

Uptake of pramipexole by human organic cation transporters.

J. Polli, Lei Diao, Y. Shu, 2010, Molecular pharmaceutics.

Novel Inhibitors of Human Organic Cation/Carnitine Transporter (hOCTN2) via Computational Modeling and In Vitro Testing

Sean Ekins, James E. Polli, Lei Diao, 2009, Pharmaceutical Research.

Lack of association between generic brittleness and neuropsychiatric measures in patients with epilepsy

J. Polli, T. Ting, Wenlei Jiang, 2022, Epilepsy & Behavior.

Biowaiver Monograph for Immediate-Release Solid Oral Dosage Forms: Amoxicillin Trihydrate.

J. Polli, A. Parr, V. Shah, 2017, Journal of pharmaceutical sciences.

Biowaiver Monographs for Immediate-Release Solid Oral Dosage Forms: Nifedipine.

J. Polli, V. Shah, J. Dressman, 2015, Journal of pharmaceutical sciences.

Biowaiver Monograph for Immediate-Release Solid Oral Dosage Forms: Ondansetron.

J. Polli, A. Parr, V. Shah, 2019, Journal of pharmaceutical sciences.

Lack of Association of Generic Brittle Status with Genetics and Physiologic Measures in Patients with Epilepsy

J. Polli, Yan Shu, T. Ting, 2020, Pharmaceutical Research.

Mechanistic interpretation of conventional Michaelis-Menten parameters in a transporter system.

J. Polli, Diana Vivian, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Design and Characterization of a Novel Fluorinated Magnetic Resonance Imaging Agent for Functional Analysis of Bile Acid Transporter Activity

J. Polli, J. Raufman, Su Xu, 2013, Pharmaceutical Research.

Increased acyclovir oral bioavailability via a bile acid conjugate.

J. Polli, A. Coop, D. Maeda, 2004, Molecular pharmaceutics.

Computational models for drug inhibition of the human apical sodium-dependent bile acid transporter.

Sean Ekins, James E Polli, J. Polli, 2009, Molecular pharmaceutics.

Lack of an Effect of Polysorbate 80 on Intestinal Drug Permeability in Humans

J. Polli, S. Hoag, S. Ekins, 2022, Pharmaceutical Research.

Novel nitroxide-bile acid conjugates inform substrate requirements for human bile acid transporters

J. Polli, J. Raufman, Joseph P. Y. Kao, 2022, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Computational Modeling to Accelerate the Identification of Substrates and Inhibitors for Transporters That Affect Drug Disposition

J. Polli, S. Ekins, P. Swaan, 2012, Clinical pharmacology and therapeutics.

Biowaiver Monograph for Immediate-Release Solid Oral Dosage Forms: Levocetirizine dihydrochloride.

Naseem A. Charoo, J. Polli, A. Parr, 2022, Journal of pharmaceutical sciences.

Ion pair-mediated transport of metoprolol across a three lipid-component PAMPA system.

J. Polli, Anand Balakrishnan, K. Hom, 2006, Journal of controlled release : official journal of the Controlled Release Society.

Biopharmaceutic Risk Assessment of Brand and Generic Lamotrigine Tablets.

J. Polli, M. Kane, T. Ting, 2015, Molecular pharmaceutics.

Selective Inhibition on Organic Cation Transporters by Carvedilol Protects Mice from Cisplatin-Induced Nephrotoxicity

J. Polli, Hong Yang, Qing Li, 2018, Pharmaceutical Research.

Regulatory utility of mechanistic modeling to support alternative bioequivalence approaches: A workshop overview

J. Polli, A. Babiskin, R. Walenga, 2023, CPT: Pharmacometrics & Systems Pharmacology.

Biomimetic Artificial Membrane Permeability Assay over Franz Cell Apparatus Using BCS Model Drugs

J. Polli, M. Bermejo, I. González-Álvarez, 2020, Pharmaceutics.

Effect of Common Excipients on the Oral Drug Absorption of Biopharmaceutics Classification System Class 3 Drugs Cimetidine and Acyclovir.

J. Polli, S. Hoag, M. Kane, 2016, Journal of pharmaceutical sciences.

Pharmacokinetics , Pharmacodynamics and Drug Transport and Metabolism Effect of Common Excipients on the Oral Drug Absorption of Biopharmaceutics Classi fi cation System Class 3 Drugs Cimetidine and Acyclovir

J. Polli, S. Hoag, M. Kane, 2016 .

Impact of Biopharmaceutics Classification System-based biowaivers.

J. Polli, B. Davit, J. Cook, 2010, Molecular pharmaceutics.

Novel approach to the analysis of in vitro-in vivo relationships.

G L Amidon, J. Polli, J. Crison, 1996, Journal of pharmaceutical sciences.

Establishing the suitability of model‐integrated evidence to demonstrate bioequivalence for long‐acting injectable and implantable drug products: Summary of workshop

J. Polli, R. Lionberger, J. Gobburu, 2023, CPT: pharmacometrics & systems pharmacology.

Regulatory utility of physiologically‐based pharmacokinetic modeling to support alternative bioequivalence approaches and risk assessment: A workshop summary report

J. Polli, Yi Zhang, B. Zolnik, 2022, CPT: pharmacometrics & systems pharmacology.

Research and Education Needs for Complex Generics

J. Polli, R. Lionberger, A. Babiskin, 2021, Pharmaceutical Research.

Influence of Charge and Steric Bulk in C-24 Region on the Interaction of Bile Acids with Human Apical Sodium Dependent Bile Acid Transporter (hASBT)

J. Polli, A. Coop, Anand Balakrishnan, 2008 .

Biowaiver monographs for immediate release solid oral dosage forms: piroxicam.

D. Barends, J. Polli, V. Shah, 2014, Journal of pharmaceutical sciences.

Advancing Product Quality: a Summary of the Second FDA/PQRI Conference

G. K. Raju, Lawrence X. Yu, Larisa C Wu, 2016, The AAPS Journal.

Summary workshop report: biopharmaceutics classification system--implementation challenges and extension opportunities.

Mei-Ling Chen, Guohua Zhang, Lawrence X. Yu, 2004, Journal of pharmaceutical sciences.

Prediction of dissolution-absorption relationships from a continuous dissolution/Caco-2 system

J. Polli, M. Ginski, R. Taneja, 1999, AAPS PharmSci.

Dissolution-Hollow Fiber Membrane (D-HFM) system to anticipate biopharmaceutics risk of tablets and capsules.

J. Polli, Asmita Adhikari, P. Seo, 2022, Journal of pharmaceutical sciences.

Relationship of antiepileptic drugs to generic brittleness in patients with epilepsy

J. Polli, T. Ting, Wenlei Jiang, 2020, Epilepsy & Behavior.

Exploring generic brittleness and the demographic factors for its susceptibility in patients with epilepsy

J. Polli, T. Ting, Wenlei Jiang, 2019, Epilepsy & Behavior.

Biowaiver Monograph for Immediate-Release Solid Oral Dosage Forms: Carbamazepine.

J. Polli, A. Parr, V. Shah, 2021, Journal of pharmaceutical sciences.

Biowaiver monographs for immediate-release solid oral dosage forms: codeine phosphate.

J. Polli, G. Amidon, V. Shah, 2014, Journal of pharmaceutical sciences.

Biowaiver monograph for immediate-release solid oral dosage forms: acetylsalicylic acid.

D. Barends, J. Polli, V. Shah, 2012, Journal of pharmaceutical sciences.

PQRI Workshop Report: Application of IVIVC in Formulation Development

Anthony J. DeStefano, Sandra Suarez-Sharp, Maziar Kakhi, 2014 .

Irinotecan Alters the Disposition of Morphine Via Inhibition of Organic Cation Transporter 1 (OCT1) and 2 (OCT2)

J. Polli, Wei Zhang, Qing Li, 2018, Pharmaceutical Research.

Computational model for predicting chemical substituent effects on passive drug permeability across parallel artificial membranes.

Alexander D. MacKerell, J. Polli, Chayan Acharya, 2008, Molecular pharmaceutics.

Putative Irreversible Inhibitors of the Human Sodium-Dependent Bile Acid Transporter (hASBT; SLC10A2) Support the Role of Transmembrane Domain 7 in Substrate Binding/Translocation

Alexander D. MacKerell, J. Polli, P. Swaan, 2012, Pharmaceutical Research.

In Vivo Magnetic Resonance Imaging to Detect Biliary Excretion of 19F-Labeled Drug in Mice

R. Gullapalli, J. Polli, M. Kane, 2011, Drug Metabolism and Disposition.

Short Communication In Vivo Magnetic Resonance Imaging To Detect Biliary Excretion of 19 F-Labeled Drug In Mice

R. Gullapalli, J. Polli, M. Kane, 2011 .

Human Drug Absorption Kinetics and Comparison to Caco-2 Monolayer Permeabilities

James E. Polli, J. Polli, Mark J. Ginski, 2004, Pharmaceutical Research.

Bioequivalence Requirements in the European Union: Critical Discussion

Jack A. Cook, Paul A. Dickinson, James E. Polli, 2012 .

Pig‐a gene mutation database

J. Polli, S. Dertinger, Katsuyoshi Horibata, 2019, Environmental and molecular mutagenesis.

Evaluation of Reproducibility of Pharmacokinetics and Clinical Outcome Differences with Brand and Generic Lamotrigine Switching in Epilepsy Patients (BEEP FU Study) (P2.033)

J. Polli, M. Kane, T. Ting, 2016 .

Generic versus brand-name lamotrigine bioequivalence in generic-sensitive epilepsy patients: a field test of the public bioequivalence standard (S31.003)

Jace W. Jones, J. Polli, M. Kane, 2015 .

Influence of Passive Permeability on Apparent P-glycoprotein Kinetics

James E. Polli, Stephen A. Wring, Joseph W. Polli, 2000, Pharmaceutical Research.

Synthesis and Evaluation of Bile Acid-Ribavirin Conjugates as Prodrugs to Target the Liver.

J. Polli, Qing Li, Yan Shu, 2015, Journal of pharmaceutical sciences.

Structural requirements of the human sodium-dependent bile acid transporter (hASBT): role of 3- and 7-OH moieties on binding and translocation of bile acids.

J. Polli, C. Lagos, W. Ward, 2014, Molecular pharmaceutics.

Metformin Disrupts Bile Acid Efflux by Repressing Bile Salt Export Pump Expression

J. Polli, S. Heyward, Shiew-Mei Huang, 2020, Pharmaceutical Research.

Validation of a method for itraconazole and major metabolite hydroxyitraconazole for LC-MS/MS analysis with application in a formulation clinical study.

J. Polli, Samuel A Krug, A. Coutinho, 2023, Journal of pharmaceutical and biomedical analysis.

Statistics on BCS Classification of Generic Drug Products Approved Between 2000 and 2011 in the USA

Lawrence X. Yu, J. Polli, M. Mehta, 2012, AAPS Journal.

Characterization of dexloxiglumide in vitro biopharmaceutical properties and active transport.

J. Polli, R. Kapil, S. Persiani, 2003, Journal of pharmaceutical sciences.

Quantitative NTCP pharmacophore and lack of association between DILI and NTCP Inhibition.

Sean Ekins, Zhongqi Dong, James E Polli, 2015, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

IVIVR versus IVIVC

J. Polli, 2000 .

Biowaiver monographs for immediate-release solid oral dosage forms: quinine sulfate.

D. Barends, J. Polli, V. Shah, 2012, Journal of pharmaceutical sciences.

Biowaiver monographs for immediate release solid oral dosage forms: amodiaquine hydrochloride.

D. Barends, J. Polli, V. Shah, 2012, Journal of pharmaceutical sciences.

Prescriber Perspectives on Biosimilar Adoption and Potential Role of Clinical Pharmacology: A Workshop Summary

Yow-Ming C Wang, J. Polli, G. Lyman, 2022, Clinical Pharmacology & Therapeutics.

Evaluation of the Physicochemical Properties of the Iron Nanoparticle Drug Products: Brand and Generic Sodium Ferric Gluconate.

J. Polli, M. Kane, M. Taraban, 2021, Molecular pharmaceutics.

Challenges in Permeability Assessment for Oral Drug Product Development

J. Polli, W. Weitschies, P. Augustijns, 2023, Pharmaceutics.