Dirk E. Smith

发表

A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma

D. Gudbjartsson, A. Sigurdsson, A. Jonasdottir, 2017, PLoS genetics.

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

Dirk E. Smith, A. Bowie, C. Jefferies, 2001, Nature.

A new mouse strain for the analysis of invariant NKT cell function

Dirk E. Smith, M. Kronenberg, Shilpi Chandra, 2015, Nature Immunology.

The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 action.

Dirk E. Smith, A. Farese, T. MacVittie, 2003, Immunity.

A central nervous system-restricted isoform of the interleukin-1 receptor accessory protein modulates neuronal responses to interleukin-1.

Dirk E. Smith, Randal R Ketchem, Yang-yang Huang, 2009, Immunity.

Neuron-Specific Effects of Interleukin-1β Are Mediated by a Novel Isoform of the IL-1 Receptor Accessory Protein

Dirk E. Smith, Yang-yang Huang, O. Ibáñez-Sandoval, 2011, The Journal of Neuroscience.

IL-33 mediates multi-walled carbon nanotube (MWCNT)-induced airway hyper-reactivity via the mobilization of innate helper cells in the lung

Dirk E. Smith, A. Holian, C. Migliaccio, 2012, Nanotoxicology.

Cutting Edge: The ST2 Ligand IL-33 Potently Activates and Drives Maturation of Human Mast Cells1

Dirk E. Smith, G. Delespesse, M. Comeau, 2007, The Journal of Immunology.

Increased density of intraepithelial mast cells in patients with exercise-induced bronchoconstriction regulated through epithelially derived thymic stromal lymphopoietin and IL-33.

W. Henderson, Dirk E. Smith, S. Ziegler, 2014, The Journal of allergy and clinical immunology.

Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis.

Dirk E. Smith, S. Viatte, C. Gabay, 2009, Arthritis and rheumatism.

The nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome/IL-1 receptor I axis mediates innate, but not adaptive, immune responses after exposure to particulate matter under 10 μm.

Dirk E. Smith, D. Sin, D. Knight, 2015, American journal of respiratory cell and molecular biology.

CD34+ hemopoietic progenitor cells are potent effectors of allergic inflammation.

Dirk E. Smith, J. Denburg, Yong‐jun Liu, 2009, The Journal of allergy and clinical immunology.

Increased density of intraepithelial mast cells in exercise-induced bronchoconstriction regulated via epithelial-derived TSLP and IL-33

W. Henderson, Dirk E. Smith, S. Ziegler, 2014 .

Four New Members Expand the Interleukin-1 Superfamily*

Dirk E. Smith, Randal R Ketchem, J. Sims, 2000, The Journal of Biological Chemistry.

Research in progress: Medical Research Council United Kingdom Refractory Asthma Stratification Programme (RASP-UK)

I. Pavord, A. Woodcock, Dirk E. Smith, 2015, Thorax.

IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms

Dirk E. Smith, D. Herbert, Li-Yin Hung, 2012, Proceedings of the National Academy of Sciences.

Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine–driven inflammation and fibrosis

Dirk E. Smith, T. Wynn, Robert W. Thompson, 2016, Science Translational Medicine.

Large-scale gene expression profiling reveals distinct type 2 inflammatory patterns in chronic rhinosinusitis subtypes.

Dirk E. Smith, M. Citardi, S. Assassi, 2017, The Journal of allergy and clinical immunology.

IL-33 Drives Eosinophil Infiltration and Pathogenic Type 2 Helper T-Cell Immune Responses Leading to Chronic Experimental Ileitis.

Dirk E. Smith, James J. Lee, Derek W. Abbott, 2016, The American journal of pathology.

IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK cells.

Dirk E. Smith, M. Smithgall, R. Armitage, 2008, International immunology.

Disease severity in K/BxN serum transfer-induced arthritis is not affected by IL-33 deficiency

Dirk E. Smith, C. Gabay, A. Finckh, 2013, Arthritis Research & Therapy.

Deletion of the ST2 proximal promoter disrupts fibroblast‐specific expression but does not reduce the amount of soluble ST2 in circulation

Dirk E. Smith, M. Smithgall, D. Toy, 2012, European journal of immunology.

Human Mast Cells Potently Activates and Drives Maturation of Cutting Edge : The ST 2 Ligand IL-33

Dirk E. Smith, G. Delespesse, M. Comeau, 2007 .

IL-1 family nomenclature

L. Joosten, M. Netea, Dirk E. Smith, 2010, Nature Immunology.

Presensitizing with a Toll-like receptor 3 ligand impairs CD8 T-cell effector differentiation and IL-33 responsiveness

Dirk E. Smith, A. Adler, S. Ngoi, 2012, Proceedings of the National Academy of Sciences.

Atherosclerosis severity is not affected by a deficiency in IL‐33/ST2 signaling

Dirk E. Smith, C. Gabay, B. Kwak, 2015, Immunity, inflammation and disease.

Characteristics of asthma in U-BIOPRED severe and non-severe cohorts with distinct biomarker profiles

Dirk E. Smith, A. Rowe, I. Adcock, 2015 .

IL-33 meets allergens at the gate

Dirk E. Smith, 2018, Nature Immunology.

Genomic organization of the interleukin-1 locus.

Scott L. Taylor, Dirk E. Smith, J. Sims, 2002, Genomics.

The IL-1 receptor accessory protein (AcP) is required for IL-33 signaling and soluble AcP enhances the ability of soluble ST2 to inhibit IL-33.

Dirk E. Smith, C. Gabay, M. Smithgall, 2008, Cytokine.

Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity

Ya-Jen Chang, Dirk E. Smith, D. Umetsu, 2011, Nature Immunology.

The IL-1 family: regulators of immunity

Dirk E. Smith, J. Sims, 2010, Nature Reviews Immunology.

The biological paths of IL‐1 family members IL‐18 and IL‐33

Dirk E. Smith, 2011, Journal of leukocyte biology.

Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity.

Dirk E. Smith, D. Umetsu, P. Savage, 2012, The Journal of allergy and clinical immunology.

Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection

Dirk E. Smith, F. Finkelman, T. Wang, 2012, The Journal of experimental medicine.

IL-33 promotes gastrointestinal allergy in a TSLP-independent manner

Dirk E. Smith, S. Ziegler, P. Bryce, 2017, Mucosal Immunology.

Identification and Characterization of Two Members of a Novel Class of the Interleukin-1 Receptor (IL-1R) Family

Dirk E. Smith, T. Born, J. Sims, 2000, The Journal of Biological Chemistry.

35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts.

Thomas J. Smith, B. M. Rasmussen, V. C. Phan, 1999, Diabetologia.

Innate lymphoid cells responding to IL-33 mediate airway- hyperreactivity independent of adaptive immunity

Dirk E. Smith, D. Umetsu, P. Savage, 2011 .

A Single Amino Acid Difference between Human and Monkey Interleukin (IL)-1β Dictates Effective Binding to Soluble Type II IL-1 Receptor*

Dirk E. Smith, Randal R Ketchem, D. Friend, 2002, The Journal of Biological Chemistry.

Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways

Dirk E. Smith, J. Johnston, O. Homann, 2018, bioRxiv.

A national demonstration site for acid sulfate soil remediation in the Australian tropics - an overview of the East Trinity environmental success story

Dirk E. Smith, A. McElnea, R. Bush, 2010 .

Lime-assisted tidal exchange reduces acidity of dyked acid sulfate soil at East Trinity, northern Australia

Dirk E. Smith, A. McElnea, L. Sullivan, 2008 .

IL-33 Drives Augmented Responses to Ozone in Obese Mice

Dirk E. Smith, B. Levy, D. Umetsu, 2016, Environmental health perspectives.

Geophysics of Ceres from Dawn

C. Russell, M. Zuber, Dirk E. Smith, 2015 .

Brain-specific interleukin-1 receptor accessory protein in sleep regulation.

Dirk E. Smith, J. Krueger, P. Taishi, 2012, Journal of applied physiology.

Using nuclear and organelle DNA markers to discriminate among Picea rubens, Picea mariana, and their hybrids

Dirk E. Smith, R. Eckert, D. Guenette, 1996 .

A central nervous system-restricted isoform of the interleukin-1 receptor accessory protein modulates neuronal responses to interleukin-1.

Dirk E. Smith, Randal R Ketchem, Yang-yang Huang, 2009, Immunity.

Increased density of intraepithelial mast cells in patients with exercise-induced bronchoconstriction regulated through epithelially derived thymic stromal lymphopoietin and IL-33.

W. Henderson, Dirk E. Smith, S. Ziegler, 2014, The Journal of allergy and clinical immunology.