Gardar Sveinbjornsson

发表

A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma

D. Gudbjartsson, A. Sigurdsson, A. Jonasdottir, 2017, PLoS genetics.

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing

Karsten B. Sieber, Benjamin B. Sun, Audrey Y. Chu, 2019 .

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

Karsten B. Sieber, Nicholette D. Palmer, Benjamin B. Sun, 2019, Nature Communications.

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology

Tanya M. Teslovich, Jonathan H. Chung, Ellen M. Schmidt, 2018, Nature Genetics.

Genome-wide association study of 1 million people identifies 111 loci for atrial fibrillation

Tanya M. Teslovich, Jonathan H. Chung, Ellen M. Schmidt, 2018, bioRxiv.

Variants with large effects on blood lipids and the role of cholesterol and triglycerides in coronary disease

D. Gudbjartsson, A. Sigurdsson, Á. Jónasdóttir, 2016, Nature Genetics.

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

Karsten B. Sieber, M. P. Concas, Cassandra N. Spracklen, 2019, Nature Genetics.

Weighting sequence variants based on their annotation increases power of whole-genome association studies

Anders Albrechtsen, Kari Stefansson, Florian Zink, 2016, Nature Genetics.

Humoral Immune Response to SARS-CoV-2 in Iceland

A. Gylfason, D. Gudbjartsson, A. Sigurdsson, 2020, The New England journal of medicine.

The genetic architecture of age-related hearing impairment revealed by genome-wide association analysis

Hannes P. Eggertsson, Bjarni V. Halldórsson, A. Gylfason, 2021, Communications biology.

Common and rare variants associating with serum levels of creatine kinase and lactate dehydrogenase

D. Gudbjartsson, A. Jonasdottir, Á. Jónasdóttir, 2016, Nature Communications.

Mapping the human genetic architecture of COVID-19

Mattia G. Bergomi, Christopher M. DeBoever, Matthew A. Wiles, 2021, Nature.

Genetic insight into sick sinus syndrome

D. Gudbjartsson, H. Ullum, U. Thorsteinsdóttir, 2021, European heart journal.

Sequence variants with large effects on cardiac electrophysiology and disease

D. Gudbjartsson, U. Thorsteinsdóttir, K. Stefánsson, 2019, Nature Communications.

Spread of SARS-CoV-2 in the Icelandic Population

Kari Stefansson, Thorolfur Gudnason, Aslaug Jonasdottir, 2020, The New England journal of medicine.

Variants in NKX2-5 and FLNC Cause Dilated Cardiomyopathy and Sudden Cardiac Death

D. Gudbjartsson, A. Jonasdottir, Á. Jónasdóttir, 2018, Circulation. Genomic and precision medicine.

Identification of sequence variants influencing immunoglobulin levels

Bjarni V. Halldórsson, A. Gylfason, B. Halldórsson, 2017, Nature Genetics.

Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

Karsten B. Sieber, Laurent F. Thomas, Pashupati P. Mishra, 2022, Kidney international.

HLA class II sequence variants influence tuberculosis risk in populations of European ancestry

Bjarni V. Halldórsson, A. Gylfason, B. Halldórsson, 2016, Nature Genetics.

Genome-wide association meta-analysis yields 20 loci associated with gallstone disease

D. Gudbjartsson, U. Thorsteinsdóttir, K. Stefánsson, 2018, Nature Communications.

Genetic effects on the timing of parturition and links to fetal birth weight

Scott M. Williams, R. T. Lie, M. Jarvelin, 2022, Nature Genetics.

MAP1B mutations cause intellectual disability and extensive white matter deficit

H. Stefánsson, A. Ingason, S. Steinberg, 2018, Nature Communications.

A catalog of genetic loci associated with kidney function from analyses of a million individuals

Karsten B. Sieber, Nicholette D. Palmer, Cassandra N. Spracklen, 2019, Nature Genetics.

The sequences of 150,119 genomes in the UK Biobank

Hannes P. Eggertsson, Brynja D. Sigurpálsdóttir, Pall I. Olason, 2021, Nature.

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

M. P. Concas, May E. Montasser, Henry J. Lin, 2019, bioRxiv.

Truncating mutations in RBM12 are associated with psychosis

H. Stefánsson, S. Steinberg, E. Sigurdsson, 2017, Nature Genetics.

Author Correction: Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology

Laurent F. Thomas, J. V. van Meurs, R. Mägi, 2022, Nature Communications.

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Nathan A. Bihlmeyer, Henry J. Lin, Blair H. Smith, 2018, Genome Biology.

Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis

D. Gudbjartsson, A. Sigurdsson, U. Thorsteinsdóttir, 2018, Nature Genetics.

A catalog of genetic loci associated with kidney function from analyses of a million individuals

Karsten B. Sieber, M. P. Concas, Nicholette D. Palmer, 2019, Nature Genetics.

Genetic variants associated with syncope implicate neural and autonomic processes.

Hannes P. Eggertsson, D. Gudbjartsson, T. Thorgeirsson, 2023, European heart journal.

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

M. Jarvelin, C. Gieger, D. Strachan, 2018, Nature Genetics.

A rare missense mutation in MYH6 confers high risk of coarctation of the aorta

D. Gudbjartsson, U. Thorsteinsdóttir, K. Stefánsson, 2017, bioRxiv.

Sequence variants associating with urinary biomarkers

Bjarni V. Halldórsson, B. Halldórsson, D. Gudbjartsson, 2018, Human molecular genetics.

GWAS of Hematuria

D. Gudbjartsson, K. Stefánsson, A. Paterson, 2022, Clinical journal of the American Society of Nephrology : CJASN.

Sequence Variants in TAAR5 and Other Loci Affect Human Odor Perception and Naming

Bjarni V. Halldórsson, H. Stefánsson, B. Halldórsson, 2020, Current Biology.

Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology

Laurent F. Thomas, J. V. van Meurs, R. Mägi, 2022, Nature communications.

Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits

Bjarni V. Halldórsson, A. Ingason, B. Halldórsson, 2018, Nature Communications.

Large-scale integration of the plasma proteome with genetics and disease

Bjarni V. Halldórsson, H. Stefánsson, B. Halldórsson, 2021, Nature Genetics.

Genetic variability in the absorption of dietary sterols affects the risk of coronary artery disease

H. Stefánsson, D. Gudbjartsson, H. Ullum, 2020, European heart journal.

Coding variants in RPL3L and MYZAP increase risk of atrial fibrillation

B. Halldórsson, D. Gudbjartsson, U. Thorsteinsdóttir, 2018, Communications Biology.

Mutations in RPL3L and MYZAP increase risk of atrial fibrillation

Bjarni V. Halldórsson, B. Halldórsson, D. Gudbjartsson, 2017, bioRxiv.

A Missense Variant in PLEC Increases Risk of Atrial Fibrillation.

D. Gudbjartsson, U. Thorsteinsdóttir, K. Stefánsson, 2017, Journal of the American College of Cardiology.

Reconstruction of a large-scale outbreak of SARS-CoV-2 infection in Iceland informs vaccination strategies

A. Gylfason, D. Gudbjartsson, A. Sigurdsson, 2021, Clinical Microbiology and Infection.

Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis

A. Gylfason, B. Halldórsson, D. Gudbjartsson, 2020, Nature Communications.

Associations of autozygosity with a broad range of human phenotypes

May E. Montasser, Annelot M. Dekker, Blair H. Smith, 2019, Nature Communications.

Sequence variant at 8q24.21 associates with sciatica caused by lumbar disc herniation

H. Stefánsson, D. Gudbjartsson, T. Thorgeirsson, 2017, Nature Communications.

A truncating mutation in EPOR leads to hypo-responsiveness to erythropoietin with normal haemoglobin

D. Gudbjartsson, U. Thorsteinsdóttir, K. Stefánsson, 2018, Communications Biology.

Common and Rare Sequence Variants Influencing Tumor Biomarkers in Blood

D. Gudbjartsson, T. Thorgeirsson, U. Thorsteinsdóttir, 2019, Cancer Epidemiology, Biomarkers & Prevention.

Dyslipidemia, inflammation, calcification, and adiposity in aortic stenosis: a genome-wide study

D. Gudbjartsson, U. Thorsteinsdóttir, K. Stefánsson, 2023, European heart journal.

Age and Influenza-Specific Pre-Vaccination Antibodies Strongly Affect Influenza Vaccine Responses in the Icelandic Population whereas Disease and Medication Have Small Effects

D. Gudbjartsson, Gardar Sveinbjornsson, I. Jónsdóttir, 2018, Front. Immunol..

Loss-of-Function Variants in the Tumor-Suppressor Gene PTPN14 Confer Increased Cancer Risk

Hannes P. Eggertsson, Pall I. Olason, Bjarni V. Halldórsson, 2021, Cancer Research.

Predicted loss and gain of function mutations in ACO1 are associated with erythropoiesis

D. Gudbjartsson, A. Jonasdottir, Á. Jónasdóttir, 2020, Communications Biology.

Corrigendum: Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis.

H. Stefánsson, D. Gudbjartsson, A. Sigurdsson, 2017, Nature genetics.

Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis

H. Stefánsson, D. Gudbjartsson, A. Sigurdsson, 2017, Nature Genetics.

Sequence variant at 8 q 24 . 21 associates with sciatica caused by lumbar disc herniation

H. Stefánsson, D. Gudbjartsson, T. Thorgeirsson, 2017 .

Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

Karsten B. Sieber, M. P. Concas, Nicholette D. Palmer, 2022, Communications Biology.

Genome-wide association and HLA fine mapping studies identify risk loci and genetic 1 pathways of allergic rhinitis

Manuel A. R. Ferreira, M. Jarvelin, C. Gieger, 2018 .

Rare mutations associating with serum creatinine and chronic kidney disease.

Kari Stefansson, Runolfur Palsson, Aslaug Jonasdottir, 2014, Human molecular genetics.

Physical and cognitive impact following SARS-CoV-2 infection in a large population-based case-control study

H. Stefánsson, E. Sigurdsson, D. Gudbjartsson, 2023, Communications medicine.

Multiomics study of nonalcoholic fatty liver disease

D. Gudbjartsson, U. Thorsteinsdóttir, K. Stefánsson, 2022, Nature Genetics.

Molecular benchmarks of a SARS-CoV-2 epidemic

Hannes P. Eggertsson, A. Gylfason, D. Gudbjartsson, 2021, Nature Communications.

Sequence variant affects GCSAML splicing, mast cell specific proteins, and risk of urticaria

Grimur Hjorleifsson Eldjarn, Bjarni V. Halldórsson, B. Halldórsson, 2023, Communications biology.

Distinction between the effects of parental and fetal genomes on fetal growth

D. Gudbjartsson, U. Thorsteinsdóttir, K. Stefánsson, 2021, Nature Genetics.

Early Spread of SARS-Cov-2 in the Icelandic Population

A. Gylfason, D. Gudbjartsson, A. Sigurdsson, 2020, medRxiv.

Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality

R. T. Lie, Bjarni V. Halldórsson, M. Daly, 2023, Nature communications.

Genetic architecture of band neutrophil fraction in Iceland

D. Gudbjartsson, A. Jonasdottir, Á. Jónasdóttir, 2022, Communications Biology.

Epigenetic and genetic components of height regulation

D. Gudbjartsson, U. Thorsteinsdóttir, A. Kong, 2016, Nature Communications.

A meta-analysis uncovers the first sequence variant conferring risk of Bell’s palsy

Hannes P. Eggertsson, Brynja D. Sigurpálsdóttir, Pall I. Olason, 2021, Scientific Reports.

Epigenetic and genetic components of height regulation

D. Gudbjartsson, U. Thorsteinsdóttir, A. Kong, 2016, Nature Communications.

Sequence variants affecting the genome-wide rate of germline microsatellite mutations

Hannes P. Eggertsson, Pall I. Olason, Bjarni V. Halldórsson, 2023, Nature communications.

Screening for Rare Coding Variants That Associate With the QTc Interval in Iceland

D. Gudbjartsson, K. Stefánsson, P. Sulem, 2023, Journal of the American Heart Association.

Genetic insights into resting heart rate and its role in cardiovascular disease

M. P. Concas, Henry J. Lin, S. Bandinelli, 2023, Nature communications.

Associations of autozygosity with a broad range of human phenotypes

M. P. Concas, May E. Montasser, Cassandra N. Spracklen, 2019, Nature Communications.

Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis

Bjarni V. Halldórsson, A. Gylfason, B. Halldórsson, 2020, Nature Communications.

Genome-wide association meta-analysis yields 20 loci associated with gallstone disease

D. Gudbjartsson, U. Thorsteinsdóttir, K. Stefánsson, 2018, Nature Communications.

Mapping the human genetic architecture of COVID-19

Mattia G. Bergomi, Christopher M. DeBoever, Matthew A. Wiles, 2021, Nature.

MAP1B mutations cause intellectual disability and extensive white matter deficit

H. Stefánsson, A. Ingason, S. Steinberg, 2018, Nature Communications.

A rare missense mutation in MYH6 associates with non-syndromic coarctation of the aorta

D. Gudbjartsson, U. Thorsteinsdóttir, K. Stefánsson, 2018, European heart journal.

Cholesterol not particle concentration mediates the atherogenic risk conferred by apolipoprotein B particles - A Mendelian randomization analysis.

D. Gudbjartsson, U. Thorsteinsdóttir, K. Stefánsson, 2022, European journal of preventive cardiology.

Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits

Bjarni V. Halldórsson, A. Ingason, B. Halldórsson, 2018, Nature Communications.

A truncating mutation in EPOR leads to hypo-responsiveness to erythropoietin with normal haemoglobin

D. Gudbjartsson, U. Thorsteinsdóttir, K. Stefánsson, 2018, Communications Biology.

Complex effects of sequence variants on lipid levels and coronary artery disease

Bjarni V. Halldórsson, B. Halldórsson, D. Gudbjartsson, 2023, Cell.

Coding variants in RPL3L and MYZAP increase risk of atrial fibrillation

Bjarni V. Halldórsson, D. Gudbjartsson, U. Thorsteinsdóttir, 2018, Communications Biology.

Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies LifeLines Cohort

Karsten B. Sieber, Laurent F. Thomas, Pashupati P. Mishra, 2022 .

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Henry J. Lin, Blair H. Smith, M. Waldenberger, 2018, Genome Biology.

Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis

D. Gudbjartsson, A. Sigurdsson, U. Thorsteinsdóttir, 2018, Nature Genetics.

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology

Tanya M. Teslovich, Jonathan H. Chung, Ryan D. Crawford, 2018, Nature Genetics.

Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura

Jens K. Boldsen, Pall I. Olason, Bjarni V. Halldórsson, 2023, Nature Genetics.

Large-scale plasma proteomics comparisons through genetics and disease associations

Pall I. Olason, Grimur Hjorleifsson Eldjarn, Bjarni V. Halldórsson, 2023, Nature.

Large-scale comparison of immunoassay- and aptamer-based plasma proteomics through genetics and disease

Pall I. Olason, Grimur Hjorleifsson Eldjarn, Bjarni V. Halldórsson, 2022, bioRxiv.

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

Christian Gieger, David Torrents, Kari Stefansson, 2018, Nature Genetics.

Actionable Genotypes and Their Association with Life Span in Iceland.

Gudmundur A. Thorisson, Hannes P. Eggertsson, H. Stefánsson, 2023, The New England journal of medicine.

Variants at the Interleukin 1 Gene Locus and Pericarditis.

Brynja D. Sigurpálsdóttir, B. Halldórsson, A. Sigurdsson, 2023, JAMA cardiology.