M. Bycroft

发表

Estimating the contribution of engineered surface electrostatic interactions to protein stability by using double-mutant cycles.

A. Fersht, L. Serrano, A. Horovitz, 1990, Biochemistry.

Comparative binding of p53 to its promoter and DNA recognition elements.

A. Fersht, M. Bycroft, R. Weinberg, 2005, Journal of molecular biology.

Hot-spot mutants of p53 core domain evince characteristic local structural changes.

M Bycroft, A. Fersht, M. Bycroft, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Molecular mechanism of the interaction between MDM2 and p53.

A. Fersht, M. Bycroft, S. Freund, 2002, Journal of molecular biology.

Biophysical characterization of elongin C from Saccharomyces cerevisiae.

A. Fersht, M. Bycroft, M. Proctor, 2000, Biochemistry.

Aromatic-aromatic interactions and protein stability. Investigation by double-mutant cycles.

L Serrano, M Bycroft, A. Fersht, 1991, Journal of molecular biology.

Strength and co-operativity of contributions of surface salt bridges to protein stability.

A. Fersht, L. Serrano, A. Horovitz, 1990, Journal of molecular biology.

Surface electrostatic interactions contribute little of stability of barnase.

A. Fersht, M. Bycroft, D. Sali, 1991, Journal of molecular biology.

Transient folding intermediates characterized by protein engineering

Andreas Matouschek, Luis Serrano, A. Fersht, 1990, Nature.

An integrated computational approach can classify VHL missense mutations according to risk of clear cell renal carcinoma

T. Blundell, M. Bycroft, Á. Olivera-Nappa, 2014, Human molecular genetics.

The folding of an enzyme. V. H/2H exchange-nuclear magnetic resonance studies on the folding pathway of barnase: complementarity to and agreement with protein engineering studies.

A. Fersht, L. Serrano, M. Bycroft, 1992, Journal of molecular biology.

The structure of a LysM domain from E. coli membrane-bound lytic murein transglycosylase D (MltD).

M Bycroft, A. Bateman, M. Bycroft, 2000, Journal of molecular biology.

The Solution Structure of the S1 RNA Binding Domain: A Member of an Ancient Nucleic Acid–Binding Fold

Mark Proctor, T. Hubbard, A. Murzin, 1997, Cell.

The Structure of the AXH Domain of Spinocerebellar Ataxin-1*

Jan Löwe, Yu Wai Chen, M. Bycroft, 2004, Journal of Biological Chemistry.

Role of Conformational Heterogeneity in Domain Swapping and Adapter Function of the Cks Proteins*

M. Karplus, M. Bycroft, L. Itzhaki, 2005, Journal of Biological Chemistry.

Identification of the barstar binding site of barnase by NMR spectroscopy and hydrogen‐deuterium exchange

A. Fersht, M. Bycroft, Mark Bycroft, 1993, FEBS letters.

Determination of the three-dimensional solution structure of barnase using nuclear magnetic resonance spectroscopy

Alan R. Fersht, Flemming M. Poulsen, A. Fersht, 1991 .

Solution structure of a soluble fragment derived from a membrane protein by shotgun proteolysis

M. Bycroft, A. Buckle, S. Freund, 2015, Protein engineering, design & selection : PEDS.

Amperometric enzyme electrodes: Part III. A conducting salt electrode for the oxidation of four different flavoenzymes

M. Bycroft, P. Bartlett, W. J. Albery, 1987 .

The ligand-binding loops in the tunicate C-type lectin TC14 are rigid.

M. Bycroft, M. Howard, S. Freund, 2001, Biochemistry.

Characterization of phosphate binding in the active site of barnase by site-directed mutagenesis and NMR.

M Bycroft, A. Fersht, M. Bycroft, 1991, Biochemistry.

Assignment of histidine resonances in the 1H NMR (500 MHz) spectrum of subtilisin BPN' using site-directed mutagenesis.

A. Fersht, M. Bycroft, 1988, Biochemistry.

Structure of the BRK domain of the SWI/SNF chromatin remodeling complex subunit BRG1 reveals a potential role in protein–protein interactions

M. Bycroft, M. Allen, G. Zinzalla, 2020, Protein science : a publication of the Protein Society.

Regulation by phosphorylation of the relative affinities of the N-terminal transactivation domains of p53 for p300 domains and Mdm2

A. Fersht, M. Bycroft, D. Teufel, 2009, Oncogene.

Mutations in Acute Myeloid Leukemia Structural Consequences of Nucleophosmin Protein Structure and Folding

M. Bycroft, Christopher M Johnson, F. Townsley, 2008 .

Structure of the Jab1/MPN domain and its implications for proteasome function.

M. Bycroft, J. Löwe, M. Allen, 2003, Biochemistry.

Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo Form of the c-MYC:MAX bHLHZip Complex Reveal a Helical Basic Region in the Absence of DNA

M. Bycroft, S. Freund, M. Allen, 2019, Biochemistry.

Recruitment of TBK1 to cytosol‐invading Salmonella induces WIPI2‐dependent antibacterial autophagy

M. Bycroft, S. Bloor, M. Allen, 2016, The EMBO journal.

The SWI/SNF Subunit INI1 Contains an N-Terminal Winged Helix DNA Binding Domain that Is a Target for Mutations in Schwannomatosis

M. Bycroft, S. Freund, M. Allen, 2015, Structure.

The UBAP1 Subunit of ESCRT-I Interacts with Ubiquitin via a SOUBA Domain

M. Bycroft, Roger L. Williams, K. Hofmann, 2012, Structure.

The Structure of the Fyr Domain of Transforming Growth Factor Beta Regulator 1 (Tbrg1)(Pna)

M. Bycroft, A. Joerger, M. Garcia-Alai, 2010 .

Refolding of barnase mutants and pro‐barnase in the presence and absence of GroEL.

A. Fersht, M. Bycroft, A. G. Day, 1993, The EMBO journal.

The structure of a tunicate C-type lectin from Polyandrocarpa misakiensis complexed with D -galactose.

M. Bycroft, Roger L. Williams, M. Proctor, 1999, Journal of molecular biology.

Equilibrium dissociation and unfolding of the dimeric human papillomavirus strain‐16 E2 DNA‐binding domain

M. Bycroft, Y. Mok, G. D. P. Gay, 1996, Protein science : a publication of the Protein Society.

Letter to Editor: Solution structure of the HPV-16 E2 DNA binding domain, a transcriptional regulator with a dimeric β-barrel fold

M. Bycroft, A. Nadra, G. de Prat-Gay, 2004 .

Structure and dynamics of barnase complexed with 3'-GMP studied by NMR spectroscopy.

A. Fersht, M. Bycroft, E. Meiering, 1993, Biochemistry.

Structural Consequences of Nucleophosmin Mutations in Acute Myeloid Leukemia*

M. Bycroft, F. Townsley, A. Warren, 2008, Journal of Biological Chemistry.

The macro domain is an ADP‐ribose binding module

M. Bycroft, M. Allen, F. Sait, 2004, The EMBO journal.

Solution Structure of the Kaposi's Sarcoma-associated Herpesvirus K3 N-terminal Domain Reveals a Novel E2-binding C4HC3-type RING Domain*

M. Bycroft, R. Read, P. Lehner, 2004, Journal of Biological Chemistry.

The Autophagy Receptor TAX1BP1 and the Molecular Motor Myosin VI Are Required for Clearance of Salmonella Typhimurium by Autophagy

M. Bycroft, M. Allen, F. Buss, 2015, PLoS pathogens.

Solution structure of the nonmethyl‐CpG‐binding CXXC domain of the leukaemia‐associated MLL histone methyltransferase

M. Bycroft, S. Freund, M. Allen, 2006, The EMBO journal.

Structure and stability of an immunoglobulin superfamily domain from twitchin, a muscle protein of the nematode Caenorhabditis elegans.

C. Chothia, M. Bycroft, J. Clarke, 1996, Journal of molecular biology.

Molecular basis of the interactions between the p73 N terminus and p300: Effects on transactivation and modulation by phosphorylation

Sarah W. Burge, A. Fersht, M. Bycroft, 2009, Proceedings of the National Academy of Sciences.

Solution structure of the BRK domains from CHD7.

M. Bycroft, S. Freund, M. Allen, 2007, Journal of molecular biology.

Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1

Berthold Göttgens, B. Göttgens, M. Bycroft, 2010, Nature Structural &Molecular Biology.

The FtsK γ domain directs oriented DNA translocation by interacting with KOPS

M. Bycroft, D. Sherratt, J. Löwe, 2006, Nature Structural &Molecular Biology.

The structure of a PKD domain from polycystin‐1: implications for polycystic kidney disease

C. Chothia, A. Bateman, M. Bycroft, 1999, The EMBO journal.

Solution structure of the FCS zinc finger domain of the human polycomb group protein L(3)mbt‐like 2

M. Bycroft, S. Freund, T. Rutherford, 2009, Protein science : a publication of the Protein Society.

Crystal Structure of the Malignant Brain Tumor (MBT) Repeats in Sex Comb on Midleg-like 2 (SCML2)*

A. Murzin, M. Bycroft, M. Allen, 2003, Journal of Biological Chemistry.

The FtsK gamma domain directs oriented DNA translocation by interacting with KOPS.

M. Bycroft, D. Sherratt, J. Löwe, 2006, Nature structural & molecular biology.

NMR solution structure of a dsRNA binding domain from Drosophila staufen protein reveals homology to the N‐terminal domain of ribosomal protein S5.

A. Murzin, M. Bycroft, D. St Johnston, 1995, The EMBO journal.

VHL Mutations Linked to Type 2C von Hippel-Lindau Disease Cause Extensive Structural Perturbations in pVHL*

M. Bycroft, A. Buchberger, E. Cartwright, 2009, Journal of Biological Chemistry.

NMR structure of the alpha-hemoglobin stabilizing protein: insights into conformational heterogeneity and binding.

N. Watkins, M. Bycroft, T. Rutherford, 2004, The Journal of biological chemistry.

NMR Structure of the α-Hemoglobin Stabilizing Protein

N. Watkins, M. Bycroft, T. Rutherford, 2004, Journal of Biological Chemistry.

The UBX domain: a widespread ubiquitin-like module.

M Bycroft, M. Bycroft, M. Proctor, 2001, Journal of molecular biology.

The solution structure of the ZnF UBP domain of USP33/VDU1

M. Bycroft, M. Allen, Mark D. Allen, 2007, Protein science : a publication of the Protein Society.

The crystal structure of AF1521 a protein from Archaeoglobus fulgidus with homology to the non-histone domain of macroH2A.

M. Bycroft, A. Buckle, J. Löwe, 2003, Journal of molecular biology.

High-resolution NMR structures of the domains of Saccharomyces cerevisiae Tho1

M. Bycroft, S. Freund, M. Allen, 2014, Acta crystallographica. Section F, Structural biology communications.

Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53

A. Fersht, M. Bycroft, S. Freund, 2007, Proceedings of the National Academy of Sciences.

NMR structure of the N-terminal domain of Saccharomyces cerevisiae RNase HI reveals a fold with a strong resemblance to the N-terminal domain of ribosomal protein L9.

M. Bycroft, S. Evans, 1999, Journal of molecular biology.

Regulation of DNA binding of p53 by its C-terminal domain.

A. Fersht, M. Bycroft, R. Weinberg, 2004, Journal of molecular biology.

The structure of the FYR domain of transforming growth factor beta regulator 1

M. Bycroft, A. Joerger, M. Garcia-Alai, 2010, Protein science : a publication of the Protein Society.

Structural variation in PWWP domains.

M. Bycroft, M. Allen, L. Slater, 2003, Journal of molecular biology.

Detection and characterization of a folding intermediate in barnase by NMR

A. Fersht, L. Serrano, M. Bycroft, 1990, Nature.

The PUB Domain Functions as a p97 Binding Module in Human Peptide N-Glycanase*

M. Bycroft, M. Allen, A. Buchberger, 2006, Journal of Biological Chemistry.

The structure of an FF domain from human HYPA/FBP11.

M. Bycroft, A. Friedler, M. Allen, 2002, Journal of molecular biology.

The General Definition of the p97/Valosin-containing Protein (VCP)-interacting Motif (VIM) Delineates a New Family of p97 Cofactors*

M. Bycroft, K. Hofmann, A. Buchberger, 2011, The Journal of Biological Chemistry.

Structural basis for Pan3 binding to Pan2 and its function in mRNA recruitment and deadenylation

M. Bycroft, J. Wolf, C. Robinson, 2014, The EMBO journal.

Assignment of the backbone 1H,15N, 13C NMR resonances and secondary structure of a double‐stranded RNA binding domain from the Drosophila protein staufen

M. Bycroft, M. Proctor, D. Johnston, 1995, FEBS letters.

Stabilization of protein structure by interaction of α-helix dipole with a charged side chain

Alan R. Fersht, A. Fersht, M. Bycroft, 1988, Nature.

Three-dimensional solution structure and 13C assignments of barstar using nuclear magnetic resonance spectroscopy.

A. Fersht, M. Bycroft, S. Freund, 1994, Biochemistry.

RNA recognition by a Staufen double‐stranded RNA‐binding domain

Gabriele Varani, Andres Ramos, Stefan Freund, 2000, The EMBO journal.

Correction: The Autophagy Receptor TAX1BP1 and the Molecular Motor Myosin VI Are Required for Clearance of Salmonella Typhimurium by Autophagy

M. Bycroft, M. Allen, F. Buss, 2016, PLoS pathogens.

A high-resolution structure of the EF-hand domain of human polycystin-2

M. Bycroft, M. Allen, R. Sandford, 2014, Protein science : a publication of the Protein Society.

Crystal Structure of a Calcium-Phospholipid Binding Domain from Cytosolic Phospholipase A2*

M. Bycroft, Roger L. Williams, O. Perisic, 1998, The Journal of Biological Chemistry.

Crystallization and preliminary crystallographic studies of a SAM domain at the C-terminus of human p73α

Yu Wai Chen, M. Bycroft, M. Proctor, 2000 .

Structural basis of p63α SAM domain mutants involved in AEC syndrome

M. Bycroft, S. Freund, M. Allen, 2011, The FEBS journal.

Sequential assignment of the 1H nuclear magnetic resonance spectrum of barnase.

A. Fersht, M. Bycroft, F. Lau, 1990, Biochemistry.

Stabilization of protein structure by interaction of alpha-helix dipole with a charged side chain.

M Bycroft, A. Fersht, M. Bycroft, 1988, Nature.

Recognition of non-methyl histone marks.

M. Bycroft, 2011, Current opinion in structural biology.

Crystallization and preliminary crystallographic analysis of an acylphosphatase from the hyperthermophilic archaeon Pyrococcus horikoshii.

M. Bycroft, M. Allen, Kam-Bo Wong, 2004, Acta crystallographica. Section D, Biological crystallography.

Solution structure and thermal stability of ribosomal protein L30e from hyperthermophilic archaeon Thermococcus celer

Yu Wai Chen, M. Bycroft, Kam-Bo Wong, 2003, Protein science : a publication of the Protein Society.

Functional analysis of the post-transcriptional regulator RsmA reveals a novel RNA-binding site.

M. Bycroft, M. Allen, S. Heeb, 2006, Journal of molecular biology.

Structure of the BRK domain of the SWI/SNF chromatin remodelling complex subunit BRG1 reveals a potential role in protein-protein interactions

M. Bycroft, M. Allen, G. Zinzalla, 2020 .

A comparison of the pH, urea, and temperature-denatured states of barnase by heteronuclear NMR: implications for the initiation of protein folding.

V L Arcus, M Bycroft, A. Fersht, 1995, Journal of molecular biology.

Toward solving the folding pathway of barnase: the complete backbone 13C, 15N, and 1H NMR assignments of its pH-denatured state.

A. Fersht, M. Bycroft, V. Arcus, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Structure of the C-terminal sterile α-motif (SAM) domain of human p73α

Yu Wai Chen, A. Fersht, M. Bycroft, 2001 .

Crystal structure of ribosomal protein L30e from the extreme thermophile Thermococcus celer: thermal stability and RNA binding.

Yu Wai Chen, M. Bycroft, Kam-Bo Wong, 2003, Biochemistry.

Local breathing and global unfolding in hydrogen exchange of barnase and its relationship to protein folding pathways.

A. Fersht, M. Bycroft, J. Clarke, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Electrostatic interactions contribute to reduced heat capacity change of unfolding in a thermophilic ribosomal protein l30e.

M. Bycroft, M. Allen, Kam-Bo Wong, 2005, Journal of molecular biology.

Pathway and stability of protein folding.

A. Fersht, L. Serrano, A. Horovitz, 1991, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

The structure of INI1/hSNF5 RPT1 and its interactions with the c‐MYC:MAX heterodimer provide insights into the interplay between MYC and the SWI/SNF chromatin remodeling complex

M. Bycroft, M. Allen, G. Zinzalla, 2018, The FEBS journal.

Characterisation of urea-denatured states of an immunoglobulin superfamily domain by heteronuclear NMR.

M. Bycroft, J. Clarke, S. Freund, 1998, Journal of molecular biology.

Determination of the three-dimensional solution structure of barnase using nuclear magnetic resonance spectroscopy.

A. Fersht, M. Bycroft, F. Poulsen, 1991, Biochemistry.

SWI/SNF subunit BAF155 N-terminus structure informs the impact of cancer-associated mutations and reveals a potential drug binding site

M. Bycroft, S. Freund, M. Allen, 2021, Communications Biology.

Solution structure of the C4 zinc finger domain of HDM2

A. Fersht, M. Bycroft, A. Andreeva, 2006, Protein science : a publication of the Protein Society.

Crystallization and preliminary crystallographic analysis of a novel orange fluorescent protein from the Cnidaria tube anemone Cerianthus sp.

M. Bycroft, M. Allen, Kam-Bo Wong, 2004, Acta crystallographica. Section D, Biological crystallography.

Crystallization and preliminary crystallographic studies of a ribosomal protein L30e from the hyperthermophilic archaeon Thermococcus celer.

M. Bycroft, M. Proctor, K. B. Wong, 2001, Acta crystallographica. Section D, Biological crystallography.

Folding of a dimeric β‐barrel: Residual structure in the urea denatured state of the human papillomavirus E2 DNA binding domain

M. Bycroft, L. Lima, L. Alonso, 2008, Protein science : a publication of the Protein Society.

The malignant brain tumor repeats of human SCML2 bind to peptides containing monomethylated lysine.

M. Bycroft, S. Freund, M. Allen, 2008, Journal of molecular biology.

The dimeric DNA binding domain of the human papillomavirus E2 protein folds through a monomeric intermediate which cannot be native-like

M. Bycroft, Y. Mok, G. Prat-Gay, 1996, Nature Structural Biology.

An integrated computational approach can classify VHL missense mutations according to risk of clear cell renal carcinoma

Douglas E. V. Pires, T. Blundell, M. Bycroft, 2014, Human molecular genetics.

Structural basis of p63α SAM domain mutants involved in AEC syndrome

M. Bycroft, S. Freund, M. Allen, 2011, The FEBS journal.

Assignment of the backbone 1H and 15N NMR resonances and secondary structure characterization of barstar

A. Fersht, M. Bycroft, David N.M. Jones, 1993, FEBS letters.