M. Wittekind

发表

Backbone and side chain dynamics of uncomplexed human adipocyte and muscle fatty acid-binding proteins.

K. Constantine, M. Friedrichs, M. Wittekind, 1998, Biochemistry.

Aliphatic 1H and 13C resonance assignments for the 26-10 antibody VL domain derived from heteronuclear multidimensional NMR spectroscopy

K. Constantine, M. Friedrichs, M. Wittekind, 1993, Journal of biomolecular NMR.

Common structural changes accompany the functional inactivation of HPr by seryl phosphorylation or by serine to aspartate substitution.

M. Wittekind, M. Saier, R. Klevit, 1989, Biochemistry.

A diversity of antibody epitopes can induce signaling through the erythropoietin receptor.

A. Lim, Randal R Ketchem, M. Wittekind, 2010, Biochemistry.

Characterization of NADP+ binding to perdeuterated MurB: backbone atom NMR assignments and chemical-shift changes.

K. Constantine, M. Friedrichs, M. Wittekind, 1997, Journal of molecular biology.

Airway Delivery of Anti-influenza Monoclonal Antibodies Results in Enhanced Antiviral Activities and Enables Broad-Coverage Combination Therapies

M. Wittekind, A. Vigil, Natalia Frias-Staheli, 2020, Journal of Virology.

Localizing the NADP+ binding site on the MurB enzyme by NMR

K. Constantine, M. Friedrichs, M. Wittekind, 1996, Nature Structural Biology.

Isolation and characterization of temperature-sensitive mutations in RPA190, the gene encoding the largest subunit of RNA polymerase I from Saccharomyces cerevisiae

J. Buhler, A. Sentenac, M. Wittekind, 1988, Molecular and cellular biology.

Interaction of the RNA‐binding domain of the hnRNP C proteins with RNA.

M. Wittekind, L. Mueller, G. Dreyfuss, 1992, The EMBO journal.

An automated procedure for the assignment of protein 1HN, 15N, 13Cα, 1Hα, 13Cβ and 1Hβ resonances

M. Friedrichs, M. Wittekind, L. Mueller, 1994 .

An automated procedure for the assignment of protein 1HN, 15N, 13C alpha, 1H alpha, 13C beta and 1H beta resonances.

M. Friedrichs, M. Wittekind, L. Mueller, 1994, Journal of biomolecular NMR.

Conditional expression of RPA190, the gene encoding the largest subunit of yeast RNA polymerase I: effects of decreased rRNA synthesis on ribosomal protein synthesis

J. Buhler, M. Wittekind, M. Nomura, 1990, Molecular and cellular biology.

SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, MINIMIZED AVERAGE STRUCTURE

M. Friedrichs, M. Wittekind, V. Goldfarb, 1997 .

Isolation and characterization of PRT1, a gene required for the initiation of protein biosynthesis in Saccharomyces cerevisiae

M. Wittekind, C. McLaughlin, S. Qin, 1986, Molecular and cellular biology.

A refocused and optimized HNCA: Increased sensitivity and resolution in large macromolecules

M. Wittekind, B. Farmer, R. Venters, 1992, Journal of biomolecular NMR.

4D NMR triple-resonance experiments for assignment of protein backbone nuclei using shared constant-time evolution periods

L. Kay, M. Friedrichs, M. Wittekind, 1992 .

Sequential 1H, 13C, and 15N NMR assignments and solution conformation of apokedarcidin.

K. Constantine, M. Friedrichs, M. Wittekind, 1994, Biochemistry.

A temperature-sensitive mutant of E. coli exhibiting slow processing of exported proteins

M. Wittekind, Koreaki Ito, H. Nashimoto, 1983, Cell.

The secY-rpmJ region of the spc ribosomal protein operon in Escherichia coli: Structural alterations affecting secY expression

M. Wittekind, Koreaki Ito, C. Ueguchi, 1989, Molecular and General Genetics MGG.

HNCACB, a High-Sensitivity 3D NMR Experiment to Correlate Amide-Proton and Nitrogen Resonances with the Alpha- and Beta-Carbon Resonances in Proteins

M. Wittekind, L. Mueller, 1993 .

Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.

M. Friedrichs, M. Wittekind, V. Goldfarb, 1997, Journal of molecular biology.

Orientation of peptide fragments from Sos proteins bound to the N-terminal SH3 domain of Grb2 determined by NMR spectroscopy.

M. Wittekind, V. Goldfarb, L. Mueller, 1994, Biochemistry.

Bacteriophage Lysin CF-301, a Potent Antistaphylococcal Biofilm Agent

M. Wittekind, R. Schuch, Assaf Raz, 2017, Antimicrobial Agents and Chemotherapy.

The structure of Dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants.

M. Wittekind, J. Tokarski, K. Kish, 2006, Cancer research.

Combination Therapy With Lysin CF-301 and Antibiotic Is Superior to Antibiotic Alone for Treating Methicillin-Resistant Staphylococcus aureus–Induced Murine Bacteremia

M. Wittekind, V. Fischetti, R. Nowinski, 2013, The Journal of infectious diseases.

The structure of HPr and site-directed mutagenesis.

L. Delbaere, M. Wittekind, O. El-Kabbani, 1989, FEMS microbiology reviews.

Cell wall hydrolases and antibiotics: exploiting synergy to create efficacious new antimicrobial treatments.

M. Wittekind, R. Schuch, 2016, Current opinion in microbiology.

1H, 13C, and 15N NMR assignments and global folding pattern of the RNA-binding domain of the human hnRNP C proteins.

M. Friedrichs, M. Wittekind, L. Mueller, 1992, Biochemistry.

Solution structure of the phosphocarrier protein HPr from Bacillus subtilis by two‐dimensional NMR spectroscopy

M. Wittekind, M. Saier, R. Klevit, 1992, Protein science : a publication of the Protein Society.

Comparative studies of active site-ligand interactions among various recombinant constructs of human beta-amyloid precursor protein cleaving enzyme.

M. Wittekind, M. Witmer, J. Yanchunas, 2003, Archives of biochemistry and biophysics.

Measurements of Monoclonal Antibody Self-Association Are Correlated with Complex Biophysical Properties.

Adam Vigil, Peter M. Tessier, M. Wittekind, 2016, Molecular pharmaceutics.

Sequence-specific 1H NMR resonance assignments of Bacillus subtilis HPr: use of spectra obtained from mutants to resolve spectral overlap.

M. Wittekind, R. Klevit, J. Reizer, 1990, Biochemistry.

Enhancing Antibody Fc Heterodimer Formation through Electrostatic Steering Effects

M. Wittekind, K. Gunasekaran, M. Retter, 2010, The Journal of Biological Chemistry.

X-Ray Crystal Structures of Human Immunodeficiency Virus Type 1 Protease Mutants Complexed with Atazanavir

Steven Sheriff, Kevin Kish, Ronald E. Rose, 2007, Journal of Virology.

Native Human Monoclonal Antibodies with Potent Cross-Lineage Neutralization of Influenza B Viruses

M. Wittekind, L. Kauvar, R. Tripp, 2018, Antimicrobial Agents and Chemotherapy.

Sequential 1H and 15N NMR assignments and secondary structure of a recombinant anti-digoxin antibody VL domain.

K. Constantine, M. Wittekind, V. Goldfarb, 1992, Biochemistry.

Production of stable anti-digoxin Fv in Escherichia coli.

M. Wittekind, E. Haber, S. Ng, 1992, Molecular immunology.

Production and characterization of an antibody Fv fragment 15N-labeled in the VL domain only.

K. Constantine, M. Wittekind, V. Goldfarb, 1993, Journal of molecular biology.

Solution structure of an isolated antibody VL domain.

K. Constantine, M. Friedrichs, M. Wittekind, 1994, Journal of molecular biology.

Incorporation of 1H/13C/15N-{Ile, Leu, Val} into a Perdeuterated, 15N-Labeled Protein: Potential in Structure Determination of Large Proteins by NMR

M. Wittekind, V. Goldfarb, L. Mueller, 1996 .