B. Farmer

发表

Backbone and side chain dynamics of uncomplexed human adipocyte and muscle fatty acid-binding proteins.

K. Constantine, M. Friedrichs, M. Wittekind, 1998, Biochemistry.

Fragment-Based Drug Discovery

B. Farmer, A. Reitz, 2008 .

Refined solution structure of human profilin I

K. Constantine, M. Friedrichs, L. Mueller, 1995, Protein science : a publication of the Protein Society.

Use of 1HN-1HN NOEs to Determine Protein Global Folds in Perdeuterated Proteins

Bennett T. Farmer, Leonard D. Spicer, Luciano Mueller, 1995 .

Application of multiple-quantum filters in zero-quantum spectroscopy

B. Farmer, R. Ramachandran, L. R. Brown, 1987 .

Optimized triple resonance applied to peptides labeled only with 15N. The HN(CO)(CA) experiment

B. Farmer, 1991 .

Relay artifacts in ROESY spectra

B. Farmer, S. Macura, L. R. Brown, 1987 .

The effect of resonance offset on the cross-relaxation rate in the rotating frame

B. Farmer, L. R. Brown, 1987 .

Characterization of NADP+ binding to perdeuterated MurB: backbone atom NMR assignments and chemical-shift changes.

K. Constantine, M. Friedrichs, M. Wittekind, 1997, Journal of molecular biology.

NMR structure of a potent small molecule inhibitor bound to human keratinocyte fatty acid-binding protein.

Stephen R. Johnson, David S. Taylor, K. Constantine, 2006, Journal of medicinal chemistry.

The utilization of overlapping delays in the 3D HMQC-TOCSY experiment

B. Farmer, T. Spitzer, J. Shockcor, 1992 .

An improved method for the determination of cross-relaxation rates from NOE data

B. Farmer, L. R. Brown, S Macur, 1986 .

The effect of molecular motion on cross relaxation in the laboratory and rotating frames

B. Farmer, L. R. Brown, S. Macura, 1988 .

Localizing the NADP+ binding site on the MurB enzyme by NMR

K. Constantine, M. Friedrichs, M. Wittekind, 1996, Nature Structural Biology.

Incorporation of ω1 decoupling, uniform excitation, and diagonal suppression in a double-quantum filtered COSY experiment

B. Farmer, L. R. Brown, 1987 .

Alzheimer's Disease: No alteration in the physical state of erythrocyte membrane glycoconjugates

B. Farmer, D. Butterfield, W. Markesbery, 1985, Annals of neurology.

Simultaneous acquisition of [13C,15N]- and [15N,15N]-separated 4D gradient-enhanced NOESY spectra in proteins

L. Mueller, B. Farmer, 1994, Journal of biomolecular NMR.

INDUCED ALTERATIONS IN THE PHYSICAL STATE OF SIALIC ACID AND MEMBRANE PROTEINS IN HUMAN ERYTHROCYTE GHOSTS: IMPLICATIONS FOR THE TOPOLOGY OF THE MAJOR SIALOGLYCOPROTEIN *

B. Farmer, D. Butterfield, J. Feix, 1983, Annals of the New York Academy of Sciences.

A refocused and optimized HNCA: Increased sensitivity and resolution in large macromolecules

M. Wittekind, B. Farmer, R. Venters, 1992, Journal of biomolecular NMR.

Simultaneous [13C,15N]-HMQC, a pseudo-triple-resonance experiment

B. Farmer, 1991 .

The alteration of membrane proteins in human erythrocyte membranes induced by quinolinic acid, an endogenous neurotoxin. Correlation of effect with structure.

B. Farmer, D. Butterfield, M. M. Nicholas, 1984, Biochimica et biophysica acta.

Quinolinic acid, an endogenous metabolite with neurotoxic properties, alters the physical state of membrane proteins in human erythrocytes.

B. Farmer, D. Butterfield, 1984, Life sciences.

Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode.

C. Homon, B. Farmer, K. Qian, 2009, Journal of medicinal chemistry.

Structural Basis of Constitutive Activity and a Unique Nucleotide Binding Mode of Human Pim-1 Kinase*

Jun Li, B. Farmer, K. Qian, 2005, Journal of Biological Chemistry.

Assignment of aliphatic side-chain 1HN/15N resonances in perdeuterated proteins

B. Farmer, R. Venters, 1996, Journal of biomolecular NMR.

Triple resonance HNCCCH experiments for correlating exchangeable and nonexchangeable cytidine and uridine base protons in RNA

L. Mueller, B. Farmer, A. Pardi, 1995, Journal of biomolecular NMR.

Unambiguous through-bond sugar-to-base correlations for purines in 13C, 15N-labeled nucleic acids: The HsCsNb, HsCs(N)bCb, and HbNbCb experiments

B. Farmer, A. Pardi, E. Nikonowicz, 1994, Journal of biomolecular NMR.

High-level 2H/13C/15N labeling of proteins for NMR studies

B. Farmer, C. Fierke, R. Venters, 1995, Journal of biomolecular NMR.

Orientation of peptide fragments from Sos proteins bound to the N-terminal SH3 domain of Grb2 determined by NMR spectroscopy.

M. Wittekind, V. Goldfarb, L. Mueller, 1994, Biochemistry.

ESR studies of the erythrocyte membrane skeletal protein network: influence of the state of aggregation of spectrin on the physical state of membrane proteins, bilayer lipids, and cell surface carbohydrates.

B. Farmer, D. Butterfield, T. Harmon, 1985, Biochimica et biophysica acta.

Molecular basis of MAPK-activated protein kinase 2:p38 assembly

Bennett T. Farmer, B. Farmer, C. Pargellis, 2007, Proceedings of the National Academy of Sciences.

Rotating-frame nuclear Overhauser effect.

B. Farmer, L. R. Brown, 1989, Methods in enzymology.

Expression, purification, crystallization and preliminary crystallographic analysis of human Pim-1 kinase.

B. Farmer, K. Qian, K. Barringer, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Total structure of hormothamnin A, a toxic cyclic undecapeptide from the tropical marine cyanobacterium Hormothamnion enteromorphoides

B. Farmer, W. Gerwick, Zhi-Dong Jiang, 1992 .

2,2,6,6-Tetramethyl-4-Amino[d17]Piperidine-15N-1-OXYL as a Spin Label For Cell Surface Carbohydrates

B. Farmer, D. Butterfield, 1985 .

Selective spin labeling of terminal galactose and N-acetylgalactosamine residues on the membrane surface of erythrocytes.

B. Farmer, D. Butterfield, 1984, Journal of biochemical and biophysical methods.

Through-bond correlation of adenine protons in a 13C-labeled ribozyme

L. Mueller, B. Farmer, A. Pardi, 1994 .

ASSIGNMENT OF SIDE-CHAIN 13C RESONANCES IN PERDEUTERATED PROTEINS

B. Farmer, R. Venters, 1995 .

Generation of impossible cross-peaks between bulk water and biomolecules in solution NMR.

W Richter, B. Farmer, W. Richter, 1993, Science.

Structural and functional characterization of CFE88: Evidence that a conserved and essential bacterial protein is a methyltransferase

B. Dougherty, M. Doyle, K. Constantine, 2005, Protein science : a publication of the Protein Society.

Characterizing the use of perdeuteration in NMR studies of large proteins: 13C, 15N and 1H assignments of human carbonic anhydrase II.

B. Farmer, C. Fierke, R. Venters, 1996, Journal of molecular biology.

Chapter 7 – Fragment-Based Drug Discovery

Allen B. Reitz, Venkata Velvadapu, Bennett T. Farmer, 2015 .

Improving potency and selectivity of a new class of non-Zn-chelating MMP-13 inhibitors.

Zhaoming Xiong, B. Farmer, Qiang Zhang, 2009, Bioorganic & medicinal chemistry letters.

Incorporation of 1H/13C/15N-{Ile, Leu, Val} into a Perdeuterated, 15N-Labeled Protein: Potential in Structure Determination of Large Proteins by NMR

M. Wittekind, V. Goldfarb, L. Mueller, 1996 .

Minimizing the Water Resonance in Biological NMR: Characterization and Suppression of Intermolecular Dipolar Interactions by Multiple-Axis Gradients⊥

B. Farmer, A. Mueller, W. Warren, 1996 .