P. Brick

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Structure of tyrosyl-tRNA synthetase refined at 2.3 A resolution. Interaction of the enzyme with the tyrosyl adenylate intermediate.

P. Brick, T. Bhat, D. Blow, 1989, Journal of molecular biology.

Structural basis for the activation of phenylalanine in the non‐ribosomal biosynthesis of gramicidin S

P. Brick, E. Conti, T. Stachelhaus, 1997, The EMBO journal.

Hydrogen bonding and biological specificity analysed by protein engineering

A. Fersht, M. Waye, P. Brick, 1985, Nature.

Structural studies of the archaeal MCM complex in different functional states.

P. Brick, M. van Heel, T. Pape, 2006, Journal of structural biology.

Many crystal forms of human immunodeficiency virus reverse transcriptase.

P. Brick, D. Blow, N. Chayen, 1991, Journal of molecular biology.

The crystal structure of the lysyl-tRNA synthetase (LysU) from Escherichia coli.

Andrew D. Miller, P. Brick, A. Miller, 1995, Structure.

Crystal Structure of Foot-and-Mouth Disease Virus 3C Protease

P. Brick, S. Curry, R. Leatherbarrow, 2005, Journal of Biological Chemistry.

Structure of the Kunitz-type soybean trypsin inhibitor (STI): implication for the interactions between members of the STI family and tissue-plasminogen activator.

P. Brick, D. Blow, S. Onesti, 1998, Acta crystallographica. Section D, Biological crystallography.

X-ray and spectrophotometric studies of the binding of proflavin to the S1 specificity pocket of human alpha-thrombin.

P. Brick, C. Rivetti, E. Conti, 1998, FEBS letters.

Crystallization and preliminary diffraction studies of hydroxypyruvate reductase (D-glycerate dehydrogenase) from Hyphomicrobium methylovorum.

P. Brick, T. Mitsunaga, M. Shimao, 1992, Journal of molecular biology.

Crystallization and preliminary diffraction studies of Erythrina trypsin inhibitor.

P. Brick, D. Maeder, S. Onesti, 1989, Journal of molecular biology.

The crystallization of glucose isomerase from Arthrobacter B3728

P. Brick, D. Blow, P. Shaw, 1986 .

Crystals of Escherichia coli single-strand DNA-binding protein show that the tetramer has D2 symmetry.

J. W. Chase, T. Steitz, P. Brick, 1983, Journal of molecular biology.

The Role of Separate Domains and of Individual Amino-Acids in Enzyme Catalysis, Studied by Site-Directed Mutagenesis

A. Fersht, P. Brick, D. Blow, 1987 .

Active site of lysyl-tRNA synthetase: structural studies of the adenylation reaction.

P. Brick, S. Onesti, G. Desogus, 2000, Biochemistry.

Collagenase: a key enzyme in collagen turnover.

D. J. Hodges, P. Brick, T. Cawston, 1996, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Getting to the end of RNA: structural analysis of protein recognition of 5' and 3' termini.

Maria R. Conte, P. Brick, S. Curry, 2009, Biochimica et biophysica acta.

Structural basis for the activation of phenylalanine in the nonribosomal biosynthesis of gramicidin S the peptide product

P. Brick, T. Stachelhaus, M. Marahiel, 2013 .

Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapy.

P. Brick, D. Blow, R. Pauptit, 1997, Structure.

Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes.

P. Brick, N. Franks, E. Conti, 1996, Structure.

Crystal structure of a NAD-dependent D-glycerate dehydrogenase at 2.4 A resolution.

P. Brick, J. Goldberg, T. Yoshida, 1994, Journal of molecular biology.

Crystal structure of a Kunitz-type trypsin inhibitor from Erythrina caffra seeds.

P. Brick, D. Blow, S. Onesti, 1991, Journal of molecular biology.

Crystal structure of a deletion mutant of a tyrosyl-tRNA synthetase complexed with tyrosine.

P. Brick, D. Blow, David M. Blow, 1987, Journal of molecular biology.

Crystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sites

P. Brick, S. Curry, N. Franks, 1998, Nature Structural Biology.

Crystal structure of RPB5, a universal eukaryotic RNA polymerase subunit and transcription factor interaction target.

P. Brick, R. Weinzierl, S. Onesti, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structure and RNA binding of the Rpb4/Rpb7 subunits of human RNA polymerase II

Finn Werner, P. Brick, F. Werner, 2005, Nucleic acids research.

Crystal structure and RNA binding of the Rpb 4 / Rpb 7 subunits of human RNA polymerase II

P. Brick, F. Werner, S. Onesti, 2005 .

Structural and functional homology between the RNAP(I) subunits A14/A43 and the archaeal RNAP subunits E/F.

P. Brick, F. Werner, S. Onesti, 2003, Nucleic acids research.

Structure of an archaeal homolog of the eukaryotic RNA polymerase II RPB4/RPB7 complex.

F Werner, P. Brick, F. Werner, 2001, Molecular cell.

Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP

T. Steitz, P. Brick, R. Hamlin, 2020, Nature.

Crystal structure of cholesterol oxidase complexed with a steroid substrate: implications for flavin adenine dinucleotide dependent alcohol oxidases.

P. Brick, D. Blow, A. Vrielink, 1993, Biochemistry.

Fatty acid binding to human serum albumin: new insights from crystallographic studies.

P. Brick, S. Curry, N. Franks, 1999, Biochimica et biophysica acta.

SOYBEAN TRYPSIN INHIBITOR

P. Brick, D. Blow, S. Onesti, 1998 .

Crystallization studies on HIV-1 reverse transcriptase

P. Brick, D. Blow, L. F. Lloyd, 1992 .

Mitotic Misregulation and Human Aging

R. Schekman, T. Steitz, A. Kornberg, 2000 .

Tyrosyl-tRNA synthetase forms a mononucleotide-binding fold.

P. Brick, T. Bhat, D. Blow, 1982, Journal of molecular biology.

Structure of full-length porcine synovial collagenase reveals a C-terminal domain containing a calcium-linked, four-bladed beta-propeller.

B. Hazleman, P. Brick, B. Hazleman, 1995, Structure.

Structure and function of the serine pathway enzymes in Hyphomicrobium

P. Brick, T. Mitsunaga, Yasuhiro Tanaka, 1996 .

The Elongator subunit Elp3 contains a Fe4S4 cluster and binds S‐adenosylmethionine

P. Brick, C. Paraskevopoulou, S. Fairhurst, 2006, Molecular microbiology.

Crystallographic studies of protein-nucleic acid interaction: catabolite gene activator protein and the large fragment of DNA polymerase I.

T. Steitz, P. Brick, D. Ollis, 1983, Journal of biomolecular structure & dynamics.

Crystallization and 7 A resolution electron density map of the large fragment of Escherichia coli DNA polymerase I.

T. Steitz, P. Brick, D. Ollis, 1983, Journal of molecular biology.

Structure of a mutant of tyrosyl-tRNA synthetase with enhanced catalytic properties

P. Brick, D. Blow, K. Brown, 1987, Nature.

Structural basis for the inhibition of firefly luciferase by a general anesthetic.

P. Brick, A. Jenkins, W. R. Lieb, 1998, Biophysical journal.

Identification and characterization of a DNA primase from the hyperthermophilic archaeon Methanococcus jannaschii.

P. Brick, M. Rossi, F. Pisani, 1999, Nucleic acids research.

Structural basis of the Methanothermobacter thermautotrophicus MCM helicase activity

P. Brick, M. van Heel, T. Pape, 2006, Nucleic acids research.

X‐ray and spectrophotometric studies of the binding of proflavin to the S1 specificity pocket of human α‐thrombin

Elena Conti, P. Brick, C. Rivetti, 1998 .

Crystallization and preliminary diffraction studies of firefly luciferase from Photinus pyralis.

P. Brick, N. Franks, E. Conti, 1996, Acta crystallographica. Section D, Biological crystallography.

CRYSTAL STRUCTURE OF CHOLESTEROL OXIDASE COMPLEXED WITH A STEROID SUBSTRATE. IMPLICATIONS FOR FAD DEPENDENT ALCOHOL OXIDASES

P. Brick, D. Blow, A. Vrielink, 1993 .

Structure of the large fragment of E. coli DNA polymerase I complexed with dCMP

T. Steitz, P. Brick, R. Hamlin, 1984 .

Crystallization and preliminary diffraction studies of Escherichia coli lysyl-tRNA synthetase (LysU).

P. Brick, A. Miller, P. Plateau, 1994, Journal of Molecular Biology.

Structural studies of lysyl-tRNA synthetase: conformational changes induced by substrate binding.

P. Brick, P. Plateau, A. Brevet, 2000, Biochemistry.

Conventional X-ray diffraction approaches to the study of enzyme mechanism: serine proteinases, aminoacyl-tRNA synthetases and xylose isomerase

P. Brick, D. Blow, O. Smart, 1992, Philosophical Transactions of the Royal Society of London. Series A: Physical and Engineering Sciences.